Digital Commons Network^™

Arterial Spin-Labeling And Dsc Perfusion Metrics Improve Agreement In Neuroradiologists' Clinical Interpretations Of Posttreatment High-Grade Glioma Surveillance Mr Imaging-An Institutional Experience, Ghiam Yamin, Eric Tranvinh, Bryan A Lanzman, Elizabeth Tong, Syed S Hashmi, Chirag B Patel, Michael Iv

Faculty, Staff and Student Publications

Background and purpose: MR perfusion has shown value in the evaluation of posttreatment high-grade gliomas, but few studies have shown its impact on the consistency and confidence of neuroradiologists' interpretation in routine clinical practice. We evaluated the impact of adding MR perfusion metrics to conventional contrast-enhanced MR imaging in posttreatment high-grade glioma surveillance imaging.

Materials and methods: This retrospective study included 45 adults with high-grade gliomas who had posttreatment perfusion MR imaging. Four neuroradiologists assigned Brain Tumor Reporting and Data System scores for each examination on the basis of the interpretation of contrast-enhanced MR imaging and then after the addition …

Investigating Which Muscles Are Most Responsible For Tremor Through Both Experimental Data And Simulation, Daniel Benjamin Free

Theses and Dissertations

Tremor affects millions of people and many patients desire alternative treatment options to medication or neural surgery. Peripheral suppression techniques are gaining greater use, but are currently applied in a trial-and-error method. To optimize these techniques, the muscles most responsible for an individual patient's tremor need to be identified. In this dissertation, I explored two parallel paths that both could aid in identifying muscles responsible for tremor. The first method utilizies measured data and a technique (coherence) that quantifies the frequency dependent correlation between two signals. Using coherence to identify muscles contributing to tremor requires at least two parts: an …

The Aggregation Effect Of Offshore Mussel Farming On Pelagic Fishes, D Bridger, Mj Attrill, Se Rees, Ev Sheehan

School of Biological and Marine Sciences

The increase in hard artificial structures in the marine environment is contributing to ocean sprawl. As well as adding hard structure to the seabed, mussel aquaculture adds rope droppers and anchor lines to the water column, where such structure would otherwise be absent. This paper aims to monitor the effects of mussel headlines on the pelagic fish community over time, as well as to investigate whether there is an interaction between the age of cultivated mussels with the number of epibiota species and the abundance of pelagic fishes. Two surveys were carried out: a time series monitoring survey to assess …

Indigenizing The Right To A Healthy Environment, Elisabeth Parker, Heather Tanana

Pace Environmental Law Review

The most severe impacts resulting from environmental degradation are experienced by already-vulnerable populations, including Indigenous peoples. A growing number of countries are formally recognizing the basic human right to a healthy environment, which can help realize environmental and climate justice for these communities. On July 28, 2022, the United Nations General Assembly passed a landmark resolution formally recognizing the human right to a clean, healthy, and sustainable environment. The adoption of this resolution represents a pivotal moment in the understanding and implementation of a human rights-based approach to protecting the environment. However, it is important to recognize that historically, Indigenous …

Smokejumper Obituary: Bordelon, Mike (Fairbanks 1976), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Preliminary Analysis Of Native Bee Community Adjacent To Sorghum And Wheat Fields In Western Kansas, Katelyn Strack, Sarah Elzay

SACAD: Scholarly Activities

Agricultural practices have significant and often negative effects on native bee populations. It is imperative that we understand how current agricultural practices affect native bees. Sorghum (Sorghum bicolor) is cultivated heavily in western Kansas and is grown in rotation with winter wheat. This analysis presents preliminary results from a study conducted in summer 2023 in which pan traps were placed adjacent to two sorghum and two wheat fields in Ellis Co. Kansas. This data is part of a larger study examining the relationship between native bees and sorghum in western Kansas.

Preliminary Analysis of Native Bee Community Adjacent …

2023-2024 Lindenwood University Honors Convocation, Lindenwood University

Honors Convocation Programs

2023-2024 Lindenwood University Honors Convocation

Interdisciplinary Collaboration In Head And Neck Cancer Care: Optimizing Oral Health Management For Patients Undergoing Radiation Therapy, Tugce Kutuk, Alessandro Villa, Noah Kalman, Adeel Kaiser

All Publications

Radiation therapy (RT) plays a crucial role in the treatment of head and neck cancers (HNCs). This paper emphasizes the importance of effective communication and collaboration between radiation oncologists and dental specialists in the HNC care pathway. It also provides an overview of the role of RT in HNC treatment and illustrates the interdisciplinary collaboration between these teams to optimize patient care, expedite treatment, and prevent post-treatment oral complications. The methods utilized include a thorough analysis of existing research articles, case reports, and clinical guidelines, with terms such as 'dental management', 'oral oncology', 'head and neck cancer', and 'radiotherapy' included …

Interdisciplinary Collaboration In Head And Neck Cancer Care: Optimizing Oral Health Management For Patients Undergoing Radiation Therapy, Tugce Kutuk, Alessandro Villa, Noah Kalman

All Publications

Radiation therapy (RT) plays a crucial role in the treatment of head and neck cancers (HNCs). This paper emphasizes the importance of effective communication and collaboration between radiation oncologists and dental specialists in the HNC care pathway. It also provides an overview of the role of RT in HNC treatment and illustrates the interdisciplinary collaboration between these teams to optimize patient care, expedite treatment, and prevent post-treatment oral complications. The methods utilized include a thorough analysis of existing research articles, case reports, and clinical guidelines, with terms such as 'dental management', 'oral oncology', 'head and neck cancer', and 'radiotherapy' included …

Meso-Scale Seabed Quantification With Geoacoustic Inversion, Tim Sonnemann, Jan Dettmer, Charles W. Holland, Stan E. Dosso

Electrical and Computer Engineering Faculty Publications and Presentations

Abstract Knowledge of sub-seabed geoacoustic properties, for example depth dependent sound speed and porosity, is of importance for a variety of applications. Here, we present a semi-automated geoacoustic inversion method for autonomous underwater vehicle data that objectively adapts model inference to seabed structure. Through parallelized trans-dimensional Bayesian inference, we infer seabed properties along a 12 km survey track on the scale of about 10 cm and 50 m in the vertical and horizontal, respectively. The inferred seabed properties include sound speed, attenuation, density, and porosity as a function of depth from acoustic reflection coefficient data. Parameter uncertainties are quantified, and …

Continuous Mowing Differentially Affects Floral Defenses In The Noxious And Invasive Weed Solanum Elaeagnifolium In Its Native Range, Alejandro Vasquez, Alexa Alaniz, Robert K. Dearth, Rupesh R. Kariyat

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

In weeds, disturbance has been found to affect life history traits and mediate trophic interactions. In urban landscapes, mowing is an important disturbance, and we previously showed that continuous mowing leads to enhanced fitness and defense traits in Solanum elaeagnifolium, Silverleaf Nightshade (SLN). However, most studies have been focused on foliar defenses, ignoring floral defenses. In this study we examined whether continuous mowing affected floral defenses in SLN using mowed and unmowed populations in South Texas, their native range. We found flowers of mowed SLN plants larger but lighter than unmowed plants. Additionally, flowers on plants that were mowed …

Improving Pharmacokinetics Of Peptides Using Phage Display, Mallika Asar, Jessica Newton-Northup, Mette Soendergaard

Student Publications

Phage display is a versatile method often used in the discovery of peptides that targets disease-related biomarkers. A major advantage of this technology is the ease and cost efficiency of affinity selection, also known as biopanning, to identify novel peptides. While it is relatively straightforward to identify peptides with optimal binding affinity, the pharmacokinetics of the selected peptides often prove to be suboptimal. Therefore, careful consideration of the experimental conditions, including the choice of using in vitro, in situ, or in vivo affinity selections, is essential in generating peptides with high affinity and specificity that also demonstrate desirable pharmacokinetics. Specifically, …

Molecular Nano-Motors (Mnms): A Novel Delivery Modality For Oligonucleotides, Hamutal Ben Dov, Hagit Grimberg

Delivery Of Nucleic Acid Therapeutics II: Biology, Engineering And Development

Please click Additional Files below to see the full abstract.

Designing Thermostable Hermes Lipopolyplex Nanoparticles For Mrna And Synthetic Hpdna Delivery, Amy Walker, Gözde Tezcan, Hassan Idris, Matthew Walker, Ashish Dhir

Delivery Of Nucleic Acid Therapeutics II: Biology, Engineering And Development

Please click Additional Files below to see the full abstract.

Timing Along The Cardiac Cycle Modulates Neural Signals Of Reward-Based Learning, Elsa F. Fouragnan, Billy Hosking, Yin Cheung, Brooke Prakash, Matthew Rushworth, Alejandra Sel

School of Psychology

Natural fluctuations in cardiac activity modulate brain activity associated with sensory stimuli, as well as perceptual decisions about low magnitude, near-threshold stimuli. However, little is known about the relationship between fluctuations in heart activity and other internal representations. Here we investigate whether the cardiac cycle relates to learning-related internal representations – absolute and signed prediction errors. We combined machine learning techniques with electroencephalography with both simple, direct indices of task performance and computational model-derived indices of learning. Our results demonstrate that just as people are more sensitive to low magnitude, near-threshold sensory stimuli in certain cardiac phases, so are they …

The Feigned Annoyance And Frustration Test To Activate The Sympathoadrenal Medullary System, Ted W. Gehrig Iii, Lee S. Berk, Robert I. Dudley, Jo A. Smith, Lida Gharibvand, Everett B. Lohman Iii

Physical Therapy Faculty Articles and Research

When perceived as threatening, social interactions have been shown to trigger the sympathoadrenal medullary system as well as the hypothalamic-pituitary-adrenal axis resulting in a physiologic stress response. The allostatic load placed on human health and physiology in the context of acute and chronic stress can have profound health consequences. The purpose of this study was to develop a protocol for a lab-based stress stimulus using social-evaluative threat. While several valid, stress-stimulating protocols exist, we sought to develop one that triggered a physiologic response, did not require significant lab resources, and could be completed in around 10 min. We included 53 …

Enhanced Plant-Derived Vesicles For Nucleotide Delivery For Cancer Therapy, Sara Corvigno, Yuan Liu, Emine Bayraktar, Elaine Stur, Nazende Nur Bayram, Adrian Lankenau Ahumada, Supriya Nagaraju, Cristian Rodriguez-Aguayo, Hu Chen, Thanh Chung Vu, Yunfei Wen, Han Liang, Li Zhao, Sanghoon Lee, Gabriel Lopez-Berestein, Anil K Sood

Faculty, Staff and Student Publications

Small RNAs (microRNAs [miRNAs] or small interfering RNAs [siRNAs]) are effective tools for cancer therapy, but many of the existing carriers for their delivery are limited by low bioavailability, insufficient loading, impaired transport across biological barriers, and low delivery into the tumor microenvironment. Extracellular vesicle (EV)-based communication in mammalian and plant systems is important for many physiological and pathological processes, and EVs show promise as carriers for RNA interference molecules. However, some fundamental issues limit their use, such as insufficient cargo loading and low potential for scaling production. Plant-derived vesicles (PDVs) are membrane-coated vesicles released in the apoplastic fluid of …

Effect Of Chemical Enhancers On Transdermal Delivery Of Amiloride For Management Of Resistant Hypertension, Leshaodo O. Tabitha, Ashana Puri, Akeemat O Tijani, Devangi Patel, Delaram Hajiabadi,

Appalachian Student Research Forum

Resistant hypertension is a condition in which blood pressure remains above the ideal value (120/80 mmHg), despite concurrent use of three antihypertensive agents of different classes taken at maximally tolerated doses. Amiloride has been clinically proven to manage resistant hypertension in patients with multiple treatment regimens including a diuretic. Currently, it is available as an oral tablet, which is administered once daily with an oral bioavailability of 50%, which gets reduced to 30% when administered with food. In addition, gastrointestinal side effects are also reported. Patient adherence to the multi-drug treatment regimen has been found to be low in patients …

The Wolfenden Report: The Key To The English Gay Rights Movement, Ryan Hollister

The Thetean: A Student Journal for Scholarly Historical Writing

The history of homosexuality in Great Britain is long and complicated, extending all the way back to the Roman conquest. Romans had a tradition of homosexuality, but when Rome fell, churches became the authority on homosexuality, leading to numerous movements to fight against it. King Henry the 8th of England outlawed buggery, a term for anal intercourse, in 1533, and there are suspicions chat King James had homosexual relationships, but the scope of English history cannot be fully summarized in a paper of this length. Instead, this paper will focus on the British decriminalization of homosexual practices in the 1950s …

The Effects Of Various Alcohols On Hexane Production In The Pretreatment Of Lignocellulose, Noah Blevins

Dr. Jay W. Boland Undergraduate Research Symposium [2023-2024]

To meet the growing demand for biofuel, it is imperative to find more efficient methods to process nonedible biomass. Previous studies have shown low temperature alcohol pretreatment to be a viable method to extract hexane from cellulose, as would be available in lignocellulosic biomass. The purpose of this study was to fill gaps in this research, determining the optimal hydrogen bronze and alcohol to maximize the hexane output, to verify glucose was produced from the procedure, and to ensure that peaks believed to represent hexane were accurate. The results of trials performed at 195°C in sealed hydrothermal vessels with various …

Effect Of Lowered Light Quality (R:Fr Ratio) At Targeted Organs On Branching Of Trifolium Repens, M J.M Hay, Ch Robin, P C.D Newton, A Cresswell, J Tilbrook

IGC Proceedings (1977-2023)

This report examined results from four similarly conducted experiments using Trifolium repens in which the R:FR ratio but not the photosynthetically active radiation (PAR) of incident light was altered at specific organ(s) of several successive phytomers or just at a single phytomer. Results indicate the local response to lowered R:FR light treatment was similar irrespective of the number of phytomers treated. This response pattern provides the means whereby plants can initiate strong localised responses to a heterogeneous light environment.

Theoretical And Observed Relationships Between Defoliation And Partitioning In Grasses, C P.D. Birch, B Thornton

IGC Proceedings (1977-2023)

A model is presented that analyses the potential effect of vertebrate grazing on the partitioning of grasses. Its conclusions are: 1) When grazing is sufficiently frequent and severe, grasses can increase their net increase in biomass by partitioning growth to reserves. 2) Partitioning growth to reserves greatly reduces leaf growth between defoliations. After repeated clipping, dryland browntop (Agrostis castellana) and red fescue (Festuca rubra) allocated a smaller proportion of growth between defoliations to leaves than ryegrass (Lolium perenne) or rough meadow-grass (Poa trivialis). Browntop and fescue achieved less leaf growth than ryegrass …

Effects Of Light Intensity And Defoliation On The Receptiveness For Primary Induction In Festuca Pratensis Huds, Lars T. Havstad

IGC Proceedings (1977-2023)

Seedlings of Festuca pratensis Huds. (cv. Salten) were raised at three different light intensities (141, 85 or 28 (mol m-2s-1 ) for 7 weeks after emergence and then either left uncut or defoliated 40 or 80% of total leaf area, before transfer to primary induction (6°C, natural short days) for 12, 15 or 18 weeks. Percentage of heading plants was more affected by the duration of primary induction than by light intensity and defoliation prior to induction. The results lend no support to the existence of a juvenile stage in seedlings of Festuca pratensis. Defoliation had less influence on …

Water Use Efficiency In Chilean And Argentine Humid Temperate Grass-Legume Pastures, H G. Landi, M H. Wade, V Garcia De Cortazar, D E. Dalla Valle

IGC Proceedings (1977-2023)

At two sites in Argentina and Chile five levels of water input were applied to four sown pastures of varying ages during spring and summer. The pastures consisted principally of C3 grasses and legumes, some of which were sown such as Lolium perenne, Trifolium repens, Dactylis glomerata. Dry matter (DM) production was measured and related to the estimated total evapotranspiration (ET): responses were both highly linear. Both responses to ET and absolute yields were higher at the Argentinian than at the Chilean site: respectively 10.7 and 15.2 kg DM/mm water evapotranspired. Nevertheless the calculated indices of sensitivity (Ky) of Doorenbos …

Effects Of Accelerate Ageing And Low Temperatures On Germination Of Range Grasses, C Cabeza, R E. Brevedan, M G. Klich, M A. Varillas

IGC Proceedings (1977-2023)

Accelerated ageing and cold tests were used to determine the seed vigour of different valuable forage grasses from the temperate semiarid region of Argentina (Piptochaetium napostaense, Poa ligularis, Stipa longiglumis, Stipa tenuis, Digitaria californica, Pappophorum subbulbosum, Setaria leiantha, Sorghastrum pellitum, Trichloris crinita). In general, warm season species showed greater vigour than cool season species.

Leaf Anatomy And Ultrastructure Of Poa Ligularis After Defoliation And Water Stress, M G. Klich, R E. Brevedan, S C. Villamil

IGC Proceedings (1977-2023)

The objective of this study was to determine the effect of defoliation and water stress on leaf anatomy and the mesophyll cell ultrastructure of Poa ligularis. Anatomical differences were detected mainly at epidermal level. Under water stress, leaf roughness was enhanced since the epidermal-cell surface contours became conspicuous. Under defoliation the microscopic roughness decreased as a result of fewer epicuticular wax crystals being formed. Defoliation produced an enhancement of the interlamellar spaces in the irrigated plantís chloroplast. Under no defoliation conditions, chloroplast structure was not affected by water stress. When subjected to water stress, lightly defoliated plants presented chloroplasts …

Effects Of Water Stress On Germination And Seedling Growth Of Lovegrass Species, R E. Brevedan, M G. Klich, E E. Sanchez

IGC Proceedings (1977-2023)

Seeds of seven cultivars of lovegrass species Ermelo, Morpa and Tanganyika weeping lovegrass (Eragrostis curvula var. curvula, Don Eduardo INTA (E. curvula var. robusta), Cochise lovegrass (E. lehmanniana x E. trichophera), A-68 Lehmann lovegrass (E. lehmanniana Nees) and Catalina boer lovegrass (E. curvula var. conferta) were germinated at different water potentials. Total germination percentage differed within cultivars according to water availability, although there were no great differences between the germination of the cultivars within any given water potential. The only exception was Don Eduardo INTA which had lower germination values. A marked …

Leaf Growth And Anatomy During Winter Droughting Of Tetrachne Dregei Plants, M G. Klich, R E. Brevedan, H Laborde

IGC Proceedings (1977-2023)

The purpose of this work was to study the leaf growth and anatomy of Tetrachne dregei plants when they were subjected to a winter drought period. Plants were grown in semicontrolled conditions under two soil moisture regimes: irrigated and non-irrigated. Anatomical characterization was made using optical and scanning electron microscopy. No differences were found in stomatal index, stomatal length and epidermal cell size, between irrigated and non-irrigated plants. The adaxial epidermis of water stressed plants was more pubescent. Leaf abaxial epidermis of non-irrigated plants showed more intercostal plates of crystallized epicuticular wax than that of the irrigated ones. Leaf tissue …

The Interaction Between Root Distribution And Pasture Growth During Water Deficit, D J. Barker, N Dymock

IGC Proceedings (1977-2023)

Quantification of water-limited pasture growth is of interest in agriculture since it allows prediction of impaired animal production during drought, and is the basis for scheduling irrigation. Experimental work on two dairy pastures 25 km south-west of Palmerston North, New Zealand found 50% of root mass was in the top 2.3 cm of soil. Soil moisture was, similarly, not uniformly distributed down the soil profile and dried most rapidly in the top 20†cm of soil. Leaf appearance rate was more strongly correlated with water status nearer the soil surface (r = 0.52 & 0.63 for 0-5 & 10-15 cm depth, …

Effects Of Phytohormone On Lateral Bud Elongation And Acidinvertase Activity During The Regrowth Of Sorghum Bicolor M., H Nojima, Y Takasaki, A Isoda

IGC Proceedings (1977-2023)

The relationships of phytohormone and sucrose metabolism in the stem ofoesorghum after cutting were studied using the stem disks treated with various plantoegrowth regulators The release of buds after incubating was accelerated by 6-benzyladenoprine riboside (6- BAR) treatment. But, on abcisic acid (ABA) andoeindole acetic acid (IAA ) treatment the release of buds was retarded. The length ofoeelongated buds on all hormonal treatments was shorter than the non-treated at the end of incubated period tested. Invertase activities were stimulated on all hormonal treatments. On 6-BAR treatment, invertase activities were the highest. But there were no relationships between invertase activities and …