Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 75811 - 75840 of 819547

Full-Text Articles in Entire DC Network

Optimization Of Coral Restoration Along The Florida Reef Tract, Raymond Barry Banister May 2024

Optimization Of Coral Restoration Along The Florida Reef Tract, Raymond Barry Banister

Theses and Dissertations

Historically, the reefs of Florida were dominated by two framework-building corals, Acropora cervicornis and A. palmata. However, these two populations have declined by 95% since the 1970s. The predominant contributors to the coral decline have been ocean warming and disease. In response to the decline, restoration organizations were established to improve survival, growth, and reproduction. Yet, there are gaps in current restoration practices and our knowledge of effective restoration techniques. This study uses large datasets to develop models that predict the most optimal locations for coral restoration in Florida and examines the relationships between the occurrence of wild acroporids …


Improving Static Cold Storage Life Of The Human Heart Before Transplant, Juan Sebastian Rodriguez Paez May 2024

Improving Static Cold Storage Life Of The Human Heart Before Transplant, Juan Sebastian Rodriguez Paez

Theses and Dissertations

Organ storage and transportation are critical steps for the success of organ transplantation. Static cold storage (SCS) of hearts for heart transplantation (HTx) remains the standard approach. However, SCS may involve damage to the tissue resulting from extended hypothermic preservation, potentially affecting organ viability. More over, the temperature distribution on and within the heart is unknown during heart transplantation. Therefore, there is an interest to study different stages of the heart transplantation process towards determining the 3D temperature distribution on and within the heart. There could be a possibility of having a hypothermic injury in different parts of the heart …


Modelling Terrestrial And Potential Extraterrestrial Photopigments Via Density Functional Theory, Dorothea Illner May 2024

Modelling Terrestrial And Potential Extraterrestrial Photopigments Via Density Functional Theory, Dorothea Illner

Theses and Dissertations

In the search for extraterrestrial life, biosignatures play a crucial role in identifying its putative traces. A commonly known and robust biosignature is the Vegetation Red Edge (VRE), which can be described as a sharp increase of reflectance observed from a planet and stems from the light absorption of photopigments in specific regions in the electromagnetic spectrum. For Earth, this VRE is known to occur around 700 nm, however, if the photopigments absorb light in different regions and have different structures the VRE could experience a wavelenght shift.

In this work, Chlorophyll a and a potential photopigment precursor called Phot0 …


Microwave Imaging Technique For Breast Cancer Detection, Nure Alam Chowdhury May 2024

Microwave Imaging Technique For Breast Cancer Detection, Nure Alam Chowdhury

Theses and Dissertations

Breast cancer is a global problem, and it is inevitable to detect cancerous cells at early stages. In recent years, microwave imaging technology has been widely applied in biomedical applications for its non-ionizing radiation. In this study, we design a micro-strip patch antenna with an inverted T-type notch in the partial ground to detect tumor cells inside the human breast. The size of the current antenna is small enough (18 mm × 21 mm × 1.6 mm) to distribute around the breast phantom. The operating frequency has been observed from 6–14 GHz with a minimum return loss of −61.18 dB …


Denoising Diffusion Probabilistic Models Based Accelerated Mri, Alexander Francis Bugielski May 2024

Denoising Diffusion Probabilistic Models Based Accelerated Mri, Alexander Francis Bugielski

Theses and Dissertations

Magnetic Resonance Imaging (MRI) is a cornerstone in obtaining intricate visualizations of anatomy and physiological processes within the human body. However, its extensive scan duration not only causes patient discomfort but also increases the likelihood of motion-induced artifacts in the images. To address such a challenge, this study investigates deep neural network models for reconstructing high-resolution MRI images from noisy and significantly undersampled data in a supervised learning manner. Specifically, it compares three models: a conventional U-Net, a self-attentive U-Net, and an innovative probabilistic diffusion model that builds upon the self-attentive U-Net architecture. These models are evaluated on their ability …


Investigating Endothelial Damage During Ischemic Stroke Treatment Using In Vitro And Computational Models, Zackary Lorton May 2024

Investigating Endothelial Damage During Ischemic Stroke Treatment Using In Vitro And Computational Models, Zackary Lorton

Theses and Dissertations

Large vessel occlusion during acute ischemic strokes requires mechanical thrombectomy (MT) procedures using stent retrievers (SR). However, complete clot removal typically takes several attempts, which can amplify endothelial cell injury (EI). This project aims to characterize the extent of EI during MT using an in vitro vascular platform and a finite-element model (FEM). Impact of SR diameter and characterization of SR mechanical forces are assessed and correlated with human umbilical vein endothelial cell (HUVEC) response. HUVECs were seeded on fibronectin (4 µg/cm2) coated true-scale PDMS arterial phantoms with 2.5 mm luminal diameter. Test groups (n=6) either …


High Intraspecific Diversity Of Pocillopora Damicornis In Southeast Asia Reflects Adaptive Potential To Climate Change, Maria Lucille Carr May 2024

High Intraspecific Diversity Of Pocillopora Damicornis In Southeast Asia Reflects Adaptive Potential To Climate Change, Maria Lucille Carr

Theses and Dissertations

Marine heatwaves are increasing in intensity and frequency because of increased emissions of greenhouse gases. On coral reefs, warmer temperatures cause coral bleaching, mortality, and shifts in benthic composition. However, coral bleaching responses and survival vary geographically. Several hypotheses may explain such geographical differences in thermal tolerance, including the possibility that some localities may support higher intraspecific diversity than other localities, increasing the likelihood of survival of some individuals through heatwaves. Here we assessed geographic patterns of intraspecific genetic diversity in the ubiquitous coral Pocillopora damicornis. Intraspecific genetic diversity was assessed for 428 sequences across 44 sites in the Pacific …


Controlled Delivery Of Peptide And Gasotransmitter For Promoting Vascular Endothelialization, Shirin Changizi May 2024

Controlled Delivery Of Peptide And Gasotransmitter For Promoting Vascular Endothelialization, Shirin Changizi

Theses and Dissertations

Endothelial cells (ECs) are vital for maintaining proper vascular function and regulating processes such as hemostasis and inflammation. Disruption of endothelial cells integrity can lead to several pathological conditions, including coronary artery disease, vascular cognitive impairment, and dementia (VCID). Alterations in ECs distribution may lead to compromised blood-brain barrier (BBB) function, facilitating the passage of blood components and contributing to conditions such as Alzheimer's disease. Additionally, disruptions in ECs function can lead to early-stage thrombosis and intimal hyperplasia, resulting in graft failure in small-diameter (

This study aimed to develop innovative approaches for drug delivery to the BBB and TEVGs …


Unraveling The Clcc1 Interactome: Impact Of The Asp25glu Variant And Its Interaction With Sigmar1 At The Mitochondrial-Associated Er Membrane (Mam), Ilaria D'Atri, Emily Rose Martin, Liming Yang, Elizabeth Sears, Emma Baple, Andrew H. Crosby, John K. Chilton, Asami Oguro-Ando May 2024

Unraveling The Clcc1 Interactome: Impact Of The Asp25glu Variant And Its Interaction With Sigmar1 At The Mitochondrial-Associated Er Membrane (Mam), Ilaria D'Atri, Emily Rose Martin, Liming Yang, Elizabeth Sears, Emma Baple, Andrew H. Crosby, John K. Chilton, Asami Oguro-Ando

Peninsula Medical School

The endoplasmic reticulum (ER) plays an indispensable role in cellular processes, including maintenance of calcium homeostasis, and protein folding, synthesized and processing. Disruptions in these processes leading to ER stress and the accumulation of misfolded proteins can instigate the unfolded protein response (UPR), culminating in either restoration of balanced proteostasis or apoptosis. A key player in this intricate balance is CLCC1, an ER-resident chloride channel, whose essential role extends to retinal development, regulation of ER stress, and UPR. The importance of CLCC1 is further underscored by its interaction with proteins localized to mitochondria-associated endoplasmic reticulum membranes (MAMs), where it participates …


Vaid: Indexing View Designs In Visual Analytics System, Lu Ying, Aoyu Wu, Haotian Li, Zikun Deng, Ji Lan, Jiang Wu, Yong Wang, Huamin Qu, Dazhen Deng, Yingcai Wu May 2024

Vaid: Indexing View Designs In Visual Analytics System, Lu Ying, Aoyu Wu, Haotian Li, Zikun Deng, Ji Lan, Jiang Wu, Yong Wang, Huamin Qu, Dazhen Deng, Yingcai Wu

Research Collection School Of Computing and Information Systems

Visual analytics (VA) systems have been widely used in various application domains. However, VA systems are complex in design, which imposes a serious problem: although the academic community constantly designs and implements new designs, the designs are difficult to query, understand, and refer to by subsequent designers. To mark a major step forward in tackling this problem, we index VA designs in an expressive and accessible way, transforming the designs into a structured format. We first conducted a workshop study with VA designers to learn user requirements for understanding and retrieving professional designs in VA systems. Thereafter, we came up …


Automatic Grading Of Short Answers Using Large Language Models In Software Engineering Courses, Nguyen Binh Duong Ta, Yi Meng Chai May 2024

Automatic Grading Of Short Answers Using Large Language Models In Software Engineering Courses, Nguyen Binh Duong Ta, Yi Meng Chai

Research Collection School Of Computing and Information Systems

Short-answer based questions have been used widely due to their effectiveness in assessing whether the desired learning outcomes have been attained by students. However, due to their open-ended nature, many different answers could be considered entirely or partially correct for the same question. In the context of computer science and software engineering courses where the enrolment has been increasing recently, manual grading of short-answer questions is a time-consuming and tedious process for instructors. In software engineering courses, assessments concern not just coding but many other aspects of software development such as system analysis, architecture design, software processes and operation methodologies …


Unraveling The ‘Anomaly’ In Time Series Anomaly Detection: A Self-Supervised Tri-Domain Solution, Yuting Sun, Guansong Pang, Guanhua Ye, Tong Chen, Xia Hu, Hongzhi Yin May 2024

Unraveling The ‘Anomaly’ In Time Series Anomaly Detection: A Self-Supervised Tri-Domain Solution, Yuting Sun, Guansong Pang, Guanhua Ye, Tong Chen, Xia Hu, Hongzhi Yin

Research Collection School Of Computing and Information Systems

The ongoing challenges in time series anomaly detection (TSAD), including the scarcity of anomaly labels and the variability in anomaly lengths and shapes, have led to the need for a more robust and efficient solution. As limited anomaly labels hinder traditional supervised models in anomaly detection, various state-of-the-art (SOTA) deep learning (DL) techniques (e.g., self-supervised learning) are introduced to tackle this issue. However, they encounter difficulties handling variations in anomaly lengths and shapes, limiting their adaptability to diverse anomalies. Additionally, many benchmark datasets suffer from the problem of having explicit anomalies that even random functions can detect. This problem is …


Anomalyclip: Object-Agnostic Prompt Learning For Zero-Shot Anomaly Detection, Qihang Zhou, Guansong Pang, Yu Tian, Shibo He, Jiming Chen May 2024

Anomalyclip: Object-Agnostic Prompt Learning For Zero-Shot Anomaly Detection, Qihang Zhou, Guansong Pang, Yu Tian, Shibo He, Jiming Chen

Research Collection School Of Computing and Information Systems

Zero-shot anomaly detection (ZSAD) requires detection models trained using auxiliary data to detect anomalies without any training sample in a target dataset. It is a crucial task when training data is not accessible due to various concerns, e.g., data privacy, yet it is challenging since the models need to generalize to anomalies across different domains where the appearance of foreground objects, abnormal regions, and background features, such as defects/tumors on different products/ organs, can vary significantly. Recently large pre-trained vision-language models (VLMs), such as CLIP, have demonstrated strong zero-shot recognition ability in various vision tasks, including anomaly detection. However, their …


Ublade: Efficient Batch Processing For Uncertainty Graph Queries, Siyuan Yao, Yuchen Li, Shixuan Sun, Jiaxin Jiang, Bingsheng He May 2024

Ublade: Efficient Batch Processing For Uncertainty Graph Queries, Siyuan Yao, Yuchen Li, Shixuan Sun, Jiaxin Jiang, Bingsheng He

Research Collection School Of Computing and Information Systems

The study of uncertain graphs is crucial in diverse fields, including but not limited to protein interaction analysis, viral marketing, and network reliability. Processing queries on uncertain graphs presents formidable challenges due to the vast probabilistic space they encapsulate. While existing systems employ batch processing to address these challenges, their performance is often compromised by the suboptimal selection of parallel graph traversal methods, the excessive costs in random number generation, and additional sampling-loads intrinsic to batch processing. In this paper, we introduce uBlade, an efficient batch-processing framework for uncertain graph queries on multi-core CPUs. uBlade utilizes the work-efficient graph traversal, …


Local Existence Of Solutions To A Nonlinear Autonomous Pde Model For Population Dynamics With Nonlocal Transport And Competition, Michael R. Lindstrom May 2024

Local Existence Of Solutions To A Nonlinear Autonomous Pde Model For Population Dynamics With Nonlocal Transport And Competition, Michael R. Lindstrom

School of Mathematical & Statistical Sciences Faculty Publications

Highlights

  • Partial differential equation models are ubiquitous in applied sciences.

  • A partial differential equation based in ecology is studied for solution existence.

  • Energy methods and convergence analysis lead to local classical solutions.

Abstract

In this paper, we prove that a particular nondegenerate, nonlinear, autonomous parabolic partial differential equation with nonlocal mass transfer admits the local existence of classical solutions. The equation was developed to qualitatively describe temporal changes in population densities over space through accounting for location desirability and fast, long-range travel. Beginning with sufficiently regular initial conditions, through smoothing the PDE and employing energy arguments, we obtain a sequence …


May 2024 News Releases, University Of Montana--Missoula. Office Of University Relations May 2024

May 2024 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.


The Effects Of Amphibole- And Sulfide-Producing Melts On Crustal Strength In Gabbros Of Lower Oceanic Crust In Oceanic Core Complexes, Mid-Atlantic And Southwest Indian Ridges, Trevor Hoffmann May 2024

The Effects Of Amphibole- And Sulfide-Producing Melts On Crustal Strength In Gabbros Of Lower Oceanic Crust In Oceanic Core Complexes, Mid-Atlantic And Southwest Indian Ridges, Trevor Hoffmann

Master's Theses

This study investigates gabbro-cored oceanic core complexes in the slow-spreading Mid-Atlantic Ridge (MAR) and the ultraslow spreading Southwest Indian Ridge (SWIR). Dikelets are a texture found in thin section samples from these systems that form as a result of crystal-plastic deformation. Thin section samples from the Atlantis Massif, MARK Area, and 13˚-15˚ North of the MAR and the Atlantis Bank of the SWIR were observed with petrography to find these dikelets and identify what type of dikelet is present. SEM-EDS is used to identify the mineral assemblages present in the dikelets. LA-ICP-MS is used on amphibole to determine if its …


Salinity Tolerance Of Flowering Rush, Butomus Umbellatus, Andrew Coomes May 2024

Salinity Tolerance Of Flowering Rush, Butomus Umbellatus, Andrew Coomes

Master's Theses

Flowering rush is an invasive aquatic plant in North America that causes deleterious effects to native ecosystems. There are two cytotypes, a triploid and diploid, and multiple genotypes contained within the diploid cytotype currently established in the U.S. Despite its presence in river drainages connected to estuarine areas, documentation on the salinity tolerance of flowering rush is scarce. Currently, information is limited to anecdotal reports suggesting intolerance to saline conditions. A better understanding of the osmotic tolerance of this species is essential to providing insight into its’ invasive range and better inform management efforts. These studies investigated vegetative propagule germination …


Molecular Characterization Of Stress Response In Western Honey Bee (Apis Mellifera), Faizan Tahir May 2024

Molecular Characterization Of Stress Response In Western Honey Bee (Apis Mellifera), Faizan Tahir

Master's Theses

Honey bees are incredibly important for the reproduction of flowering plants and the sustainability of agricultural ecosystems. However, they face various stressors such as pesticides, pathogens, habitat loss, and climate change. Extensive research has been conducted to understand how bees respond to these stressors. Scientists have discovered that honey bees exhibit complex physiological and behavioral responses to stress at individual and colony levels. Stress can have a significant impact on their immune function, foraging behavior, and reproductive success (Decourtye et al., 2010). Understanding bee responses to stress is crucial for several reasons. Firstly, honey bees are vital for the pollination …


The Assessment Of Autonomic Function In Young Adults With An Elevated Risk Of Metabolic Syndrome, Ta'quoris Newsome May 2024

The Assessment Of Autonomic Function In Young Adults With An Elevated Risk Of Metabolic Syndrome, Ta'quoris Newsome

Master's Theses

Metabolic syndrome (MetS) is a complex medical condition defined by the co-occurrence of multiple cardiometabolic risk factors. Despite the well-defined profile of autonomic function in individuals with MetS, autonomic function in those with an elevated risk of developing MetS remains unclear. Our study aimed to shed light on the progression of cardiometabolic disease and its impact on autonomic function. To investigate, twenty participants, ten of whom were classified as having an elevated risk of developing MetS based on identification of risk factors using NCEP ATP III criteria, completed a two-visit study protocol. In the second visit, spontaneous cardiovagal baroreflex sensitivity …


The Impact Of Target Sex Typicality On Participant's Willingness To Engage In Prosocial Behaviors, Olajuwon Olagbegi May 2024

The Impact Of Target Sex Typicality On Participant's Willingness To Engage In Prosocial Behaviors, Olajuwon Olagbegi

Master's Theses

One’s decision to engage in prosocial behavior relies on various pieces of social information. The physical attractiveness of a social target could inform a perceiver’s subsequent intentions. In identifying which aspect of physical attractiveness could inform these decisions, it could be possible that prosocial decisions are heightened among those with sex-typical facial structures. This study explored the extent to which sex-typical facial structures informed perceivers’ interest in the context of social activism. Participants imagined themselves as responding to a request from a social target, deciding how behavior with high-cost and low-cost options. The male or female social target was manipulated …


Indoor Tent Management For Extending Honey Bee Research Season: Benefits And Caveats, Trevor Bawden, Adam G. Dolezal, Chelsea N. Cook May 2024

Indoor Tent Management For Extending Honey Bee Research Season: Benefits And Caveats, Trevor Bawden, Adam G. Dolezal, Chelsea N. Cook

Biological Sciences Faculty Research and Publications

Honey bees are important organisms for research in many fields, including physiology, behavior, and ecology. Honey bee colonies are relatively easy and affordable to procure, manage, and replace. However, some difficulties still exist in honey bee research, specifically that honey bee colonies have a distinct seasonality, especially in temperate regions. Honey bee colonies transition from a large society in which workers have a strict temporal division of labor in the summer, to a group of behaviorally flexible workers who manage the colony over winter. Furthermore, opening colonies or collecting bees when they are outside has the potential to harm the …


Influence Of The Atlantic Inflow On Trace Metal Enrichments In Sediments And Particulate Matter Of The Nw Alboran Sea (Sw Mediterranean), Albert Palanques, Pere Puig, Pere Masqué, Enrique Isla May 2024

Influence Of The Atlantic Inflow On Trace Metal Enrichments In Sediments And Particulate Matter Of The Nw Alboran Sea (Sw Mediterranean), Albert Palanques, Pere Puig, Pere Masqué, Enrique Isla

Research outputs 2022 to 2026

Trace metal contents and fluxes in downward particulate matter and dated sediment cores of the NW Alboran Sea are analysed in this study with the aim of assessing the role of the Atlantic inflow on their transport. Increases in Zn, Cu and Pb were detected in downward particulate matter collected by sediment traps after river flooding events and after the Aznalcollar mining spill. Their arrival coincided within the recently estimated time range for river particles discharged into the Gulf of Cádiz to reach the Alboran Sea, indicating that their transfer is enhanced during events of increased river inputs of contaminated …


A Photocrosslinkable And Hemostatic Bilayer Wound Dressing Based On Gelatin Methacrylate Hydrogel And Polyvinyl Alcohol Foam For Skin Regeneration, Asghar Eskandarinia, Mohammad H. Morowvat, Seyyed V. Niknezhad, Moloud Amini Baghbadorani, Martin Michálek, Si Chen, Mohammad M. Nemati, Manica Negahdaripour, Reza Heidari, Amir Azadi, Younes Ghasemi May 2024

A Photocrosslinkable And Hemostatic Bilayer Wound Dressing Based On Gelatin Methacrylate Hydrogel And Polyvinyl Alcohol Foam For Skin Regeneration, Asghar Eskandarinia, Mohammad H. Morowvat, Seyyed V. Niknezhad, Moloud Amini Baghbadorani, Martin Michálek, Si Chen, Mohammad M. Nemati, Manica Negahdaripour, Reza Heidari, Amir Azadi, Younes Ghasemi

Research outputs 2022 to 2026

The enormous potential of multifunctional bilayer wound dressings in various medical interventions for wound healing has led to decades of exploration into this field of medicine. However, it is usually difficult to synthesize a single hydrogel with all the required capabilities simultaneously. This paper proposes a bilayer model with an outer layer intended for hydrogel wound treatment. By adding gelatin methacrylate (GelMA) and tannic acid (TA) to the hydrogel composition and using polyvinyl alcohol-carboxymethyl chitosan (PVA-CMCs) foam layer as supports, a photocrosslinkable hydrogel with an optimal formulation was created. The hydrogels were then examined using a range of analytical procedures, …


A Computational Investigation Into Thermo-Kinetic Parameters Governing The Decomposition Of Bio-Oil Model Compounds, Ali Huseein Aljefri May 2024

A Computational Investigation Into Thermo-Kinetic Parameters Governing The Decomposition Of Bio-Oil Model Compounds, Ali Huseein Aljefri

Theses

Among notable products from thermal degradation of biomass are simple oxygen-containing aromatics. These compounds typically appear in high loads in collected bio-oil derived from biomass. As such, it is important to comprehend the decomposition chemistry of this category of compounds. This thesis takes on board a general approach to report thermo-kinetic parameters that govern decomposition of a selected set of bio-oil model compounds in two distinct systems: firstly radical-derived pathways in the gas phase and secondly thermal degradation in their condensed media. The first is attained through accurate density functional calculations while the second is accomplished through the use of …


Abnormal Cleavage Up To Day 3 Does Not Compromise Live Birth And Neonatal Outcomes Of Embryos That Have Achieved Full Blastulation: A Retrospective Cohort Study, Tammy Lee, Kelli Peirce, Jay Natalwala, Vincent Chapple, Peter J. Mark, Katherine Sanders, Yanhe Liu May 2024

Abnormal Cleavage Up To Day 3 Does Not Compromise Live Birth And Neonatal Outcomes Of Embryos That Have Achieved Full Blastulation: A Retrospective Cohort Study, Tammy Lee, Kelli Peirce, Jay Natalwala, Vincent Chapple, Peter J. Mark, Katherine Sanders, Yanhe Liu

Research outputs 2022 to 2026

STUDY QUESTION: Do embryos displaying abnormal cleavage (ABNCL) up to Day 3 have compromised live birth rates and neonatal outcomes if full blastulation has been achieved prior to transfer? SUMMARY ANSWER: ABNCL is associated with reduced full blastulation rates but does not impact live birth rates and neonatal outcomes once full blastulation has been achieved. WHAT IS KNOWN ALREADY?: It is widely accepted that ABNCL is associated with reduced implantation rates of embryos when transferred at the cleavage stage. However, evidence is scarce in the literature reporting birth outcomes from blastocysts arising from ABNCL embryos, likely because they are ranked …


Association Of Body Iron Stores And Anemia In A Ghanaian Type-2 Diabetes Mellitus Population: A Multicentered Cross-Sectional Study, Wina I.O. Boadu, William K.B.A. Owiredu, Emmanuel Timmy Donkoh, Kwame O. Boadu, Afia A. Kwayie, Joseph Frimpong, Enoch O. Anto, Christian Obirikorang, Emmanuel E. Korsah, Ezekiel Ansah, Michael Nyantakyi, Stephen Opoku, Ebenezer Senu, Elizabeth Aboagye May 2024

Association Of Body Iron Stores And Anemia In A Ghanaian Type-2 Diabetes Mellitus Population: A Multicentered Cross-Sectional Study, Wina I.O. Boadu, William K.B.A. Owiredu, Emmanuel Timmy Donkoh, Kwame O. Boadu, Afia A. Kwayie, Joseph Frimpong, Enoch O. Anto, Christian Obirikorang, Emmanuel E. Korsah, Ezekiel Ansah, Michael Nyantakyi, Stephen Opoku, Ebenezer Senu, Elizabeth Aboagye

Research outputs 2022 to 2026

Background and Aims: Anemia has been a common comorbidity in most chronic diseases, but has not been well monitored in type 2 diabetes mellitus (T2DM) patients. In this study, we investigated the prevalence of anemia and its nexus with iron stores among T2DM patients in health facilities in the Ashanti Region of Ghana. Methods: This multicenter cross-sectional study recruited 213 T2DM out-patients attending the diabetic clinics at the Kumasi South Hospital and St. Michaels Hospital, Jachie Pramso, Ghana, for routine check-ups. Self-reported questionnaires were used to collect sociodemographic, lifestyle, and clinical data from study participants. Blood samples were collected to …


Defining The Phylogenetics And Resistome Of The Major Clostridioides Difficile Ribotypes Circulating In Australia, Keeley O’Grady, Stacey Hong, Papanin Putsathit, Narelle George, Christine Hemphill, Peter G. Huntington, Tony M. Korman, Despina Kotsanas, Monica Lahra, Rodney Mcdougall, Andrew Mcglinchey, Avram Levy, Casey V. Moore, Graeme Nimmo, Louise Prendergast, Jennifer Robson, David J. Speers, Lynette Waring, Michael C. Wehrhahn, Gerhard F. Weldhagen, Richard M. Wilson, Thomas V. Riley, Daniel R. Knight May 2024

Defining The Phylogenetics And Resistome Of The Major Clostridioides Difficile Ribotypes Circulating In Australia, Keeley O’Grady, Stacey Hong, Papanin Putsathit, Narelle George, Christine Hemphill, Peter G. Huntington, Tony M. Korman, Despina Kotsanas, Monica Lahra, Rodney Mcdougall, Andrew Mcglinchey, Avram Levy, Casey V. Moore, Graeme Nimmo, Louise Prendergast, Jennifer Robson, David J. Speers, Lynette Waring, Michael C. Wehrhahn, Gerhard F. Weldhagen, Richard M. Wilson, Thomas V. Riley, Daniel R. Knight

Research outputs 2022 to 2026

Clostridioides difficile infection (CDI) remains a significant public health threat globally. New interventions to treat CDI rely on an understanding of the evolution and epidemiology of circulating strains. Here we provide longitudinal genomic data on strain diversity, transmission dynamics and antimicrobial resistance (AMR) of C. difficile ribotypes (RTs) 014/020 (n=169), 002 (n=77) and 056 (n=36), the three most prominent C. difficile strains causing CDI in Australia. Genome scrutiny showed that AMR was uncommon in these lineages, with resistance-conferring alleles present in only 15/169 RT014/020 strains (8.9 %), 1/36 RT056 strains (2.78 %) and none of 77 RT002 strains. Notably, ~90 …


Vascular Brain Digital Twins For Medical Training And Education In Metaverse, Shamma Khaled Alghafri May 2024

Vascular Brain Digital Twins For Medical Training And Education In Metaverse, Shamma Khaled Alghafri

Theses

This study addresses the need for innovative educational tools in the field of anatomy, specifically focusing on brain anatomy. The objective is to develop a virtual reality application and a 3D visualization that offer immersive and interactive learning experiences for students. The VR application, developed using Unity and designed for the Oculus Quest 2 headset, creates an immersive virtual laboratory environment. This environment includes interactive elements such as a table with buttons for displaying brain models and a whiteboard for user interaction. Users can manipulate and explore different brain structures, enhancing their understanding of complex anatomical features. Additionally, we integrated …


Exopolysaccharides Of Lactic Acid Bacteria Isolated From Labneh: Characterization, Bioactivities, And Effects On Gut Microbiome And Fermented Milk Rheology, Mohammed Tarique May 2024

Exopolysaccharides Of Lactic Acid Bacteria Isolated From Labneh: Characterization, Bioactivities, And Effects On Gut Microbiome And Fermented Milk Rheology, Mohammed Tarique

Dissertations

Exopolysaccharides (EPS), produced by Lactic Acid Bacteria (LAB), are carbohydrate polymers with unique physicochemical properties and various biological activities widely used in food and pharmaceutical industries. This dissertation is aimed to (1) screen 42 new isolates from traditional yogurt-like products (Labneh) for their probiotic nature and identify the LAB strains using 16S rDNA sequencing; (2) optimize the conditions like pH, temperature, time, and quantity of sucrose for the growth of EPS produced by four selected LAB isolates; (3) purify and characterize EPS for the contents and investigate the bioactivities of the partially purified EPS; (4) study the effects of the …