Digital Commons Network^™

What Are The Odds? Integrated Stem And Student Conceptual Understanding Of Genetics Dihybrid Inheritance, Jessica Cooper

Dissertations

Integrated Science Technology Engineering Math (STEM) education allows students to build conceptual understanding by connecting material to other content areas and real-world contexts. Strong conceptual understanding allows students to move beyond factual recall and instead synthesize and transfer their knowledge to new applications. In high school biology, students need to develop a strong conceptual understanding of genetic inheritance in the context of dihybrid inheritance. This qualitative case study was designed to understand the influence of an integrated STEM approach on student conceptual understanding of genetic dihybrid inheritance. The situated STEM learning and conceptual change theoretical frameworks guided the research design …

Conservation Of Sagebrush Ecosystems Through Diet Analysis Of An Obligate Species, Kari Felton, Alex G. Hardy, Michael A. Schroeder, Ashley Martwick, Gregory Donald Randolph, Stephanie J. Galla, Jennifer Sorensen Forbey, Stephanie F. Hudon

Idaho Conference on Undergraduate Research

Sage Grouse (Centrocercus urophasianus) is an obligate species that depends on sagebrush to survive and serves as an indicator species and umbrella species for the sagebrush ecosystem. The sagebrush ecosystem has been declining rapidly therefore understanding the impacts on Sage Grouse could aid researchers and land managers in best practices to protect the long-term viability of the species, the ecosystem, and 350 other species that depend on it, including humans. One way to understand these impacts is through dietary indicators, such as the availability of preferred forage plants. In the past, this has been done by direct observation, …

Defending The Security Of The Mind: A Mail Survey Of Thought-Reform Literacy In South Dakota, Dustin Rozario Steinhagen

Masters Theses & Doctoral Dissertations

Thought reform – also known as brainwashing or psychological manipulation – is a profound threat to the security of the human mind. This complex form of social engineering is associated with terrorist movements, domestic abuse, destructive cults, and many other forms of totalitarianism present in society (Stein, 2017). Thought reform can result in various harms that range in severity depending on each person’s individual experience (Lalich & Tobias, 2006; Stein, 2017). The work of security and privacy professionals inherently concerns psychological manipulation – thought reform often occurs over the internet (Hassan & Shah, 2019), most data breaches occur due to …

Computational Study Of Protein Dynamics And Allostery Through Molecular Modeling And Machine Learning, Sian Xiao

Chemistry Theses and Dissertations

This thesis studies the complexities of protein dynamics and allostery, presenting methodologies that leverage combined computational approaches, including molecular modeling and machine learning, to investigate these phenomena.

Protein dynamics bridge conformational ensembles and their corresponding functional states. It further plays a critical role in a wide range of biological processes. Therefore, studying protein dynamics is essential for understanding how proteins fulfill their biological functions. Allostery plays a pivotal role in biological processes, acting as a fundamental mechanism through which proteins transmit signals and regulate their activity. Despite its critical importance in biology, the specific allosteric mechanisms governing most proteins remain …

Growing South Dakota (Summer 2024), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Hayengas endow department head of animal science
[Page] 4 Reese named Klingbeil Endowed Educator
[Page] 5 SDSU Rodeo at Nationals
[Page] 6 Nwadike leading Department of Dairy and Food Science
[Page] 8 Hansen serving as 2024 Hobo Day Grand Pooba
[Page] 10 The scoop on the Davis Dairy Plant
[Page] 14 Research shows value in change
[Page] 16 Legacy of 'Yellow Ore, Yellow Hair, Yellow Pine'
[Page] 20 SDSU beef team grows
[Page] 22 SDSU Extension supporting local foods movement
[Page] 24 Bolstering rural child care needs
[Page] 26 Feeding kids great food
[Page] 27 Education Abroad takes …

Role Of Hospital Leadership In Pandemic Preparedness: Experience At A Tertiary Hospital In Kenya During The Covid-19 Pandemic, Lucy Wangari, William Macharia, Benjamin Wachira, Jemimah Kimeu, Boniface Mativa, Lukoye Atwoli

Emergency Medicine, East Africa

Introduction Pandemic preparedness refers to being ready for, responding to and recovering from public health crises, and is integral for health security. Hospital leadership is a critical building block of an effective healthcare system, providing policy, accountability and stewardship in a health crisis.

Objectives and methods We aimed to describe the leadership and governance structures put in place at the Aga Khan University Hospital, Nairobi, a private not-for-profit tertiary healthcare facility, following the COVID-19 pandemic. We reviewed over 200 hospital documents archived in the COVID-19 repository including those received from the Kenya Ministry of Health, emails, memos, bulletins, meeting minutes, …

Exploring The Functional Significance Of A Yap1 Missense Variant Of Uncertain Significance In Caenorhabditis Elegans, Nathan Jones

Theses

Polycystic ovary syndrome (PCOS) is a complex disorder with various implications, such as polycystic ovaries, visceral obesity, and increased risk of cancer. YAP1 was recently identified as a gene of interest in the development of PCOS. Researchers have established that single nucleotide variants in YAP1 are likely to play a role in PCOS development. This project aims to provide insight into the potential impact of a YAP1 variant of uncertain significance (VUS). Studies in C. elegans have established yap-1 as a nematode ortholog for human YAP1. A YAP1 VUS was identified through ClinVar, YAP1 c.1015A>G (p.Asn339Asp). Evolutionary conservation …

Effects Of Simulated Climate Change On Native Southeastern Grassland Vegetation Using Open Top Chambers, Makaila Carpenter

Theses

The southeastern United States is a critical biodiversity hotspot once covered in prairie grassland ecosystems and now facing significant threats due to urbanization, habitat destruction, over-exploitation, biological invasions, pollution, and climate change. This study analyzes the response of Alabama’s native prairie ecosystem to climate change. We used open top chambers (OTCs) to simulate climate change-induced warming. We assessed the response of ecosystem function and structure to higher temperatures (1-3^oC). The indicators of ecosystem function included phenology, leaf surface area (LSA), specific leaf area (SLA), and aboveground and below net primary productivity (ANPP and BNPP respectively). Ecosystem structure was …

Effects Of Vitis Vinifera L. Seed Extract On Short-Term Memory Of Amyloid-Beta-Mediated Neurodegeneration In Transgenic Caenorhabditis Elegans, Elise Patrick

Theses

Alzheimer's disease (AD) is a neurodegenerative condition that is a common cause of dementia and a growing concern worldwide with no effective treatment or cure. Two pathological AD hallmarks include buildup of amyloid beta (Aβ) plaques and neurofibrillary tangles in the brain. Recent attention has turned to exploring natural products and compounds for AD symptom relief and treatment. Vitis vinifera grape seed extract (GSE) contains many beneficial substances. GSE has been tested in several animal models and has shown to improve memory and is even being examined in an AD treatment human clinical trial. In this study, the aim was …

Full Issue - Spring 2024 - Volume 111, Issue 1, Colby College

Colby Magazine

05. Building on Traditional Strengths in the Sciences, Colby Plans for ‘New Ways of Knowing’
14. A Place Where Anything is Possible
38. Embracing Unmastery
60. News AI for Everyone
64. ‘A Compass for the Field’
70. Class Notes
92. In Memoriam

2024-2025 Global Feedback Report: Uni Scholarworks, University Of Northern Iowa, Rod Library

Library Documents & Reports (entire collection)

This library report was prepared by the Digital Scholarship Librarian at the University of Northern Iowa as part of assessment efforts demonstrating the reach and impact of departments and programs at the University of Northern Iowa. The global input is related to specific works found in UNI's institutional repository, UNI ScholarWorks (http://www.scholarworks.uni.edu.)

Female Foragers Sometimes Hunt, Yet Gendered Divisions Of Labor Are Real: A Comment On Anderson Et Al. (2023), The Myth Of Man The Hunter, Vivek V. Venkataraman, Jordie Hoffman, Kyle Farquharson, Helen Elizabeth Davis, Edward H. Hagen, Raymond B. Hames, Barry S. Hewlett, Luke Glowacki, Haneul Jang, Robert Kelly, Karen Kramer, Sheina Lew-Levy, Katie Starkweather, Kristen Syme, Duncan N. E. Stibbard-Hawkes

Department of Anthropology: Faculty Publications

Gendered divisions of labor are a feature of every known contemporary hunter-gatherer (forager) society. While gender roles are certainly flexible, and prominent and well-studied cases of female hunting do exist, it is more often men who hunt. A new study (Anderson et al., 2023) surveyed ethnographically known foragers and found that women hunt in 79% of foraging societies, with big-game hunting occurring in 33%. Based on this single type of labor, which is one among dozens performed in foraging societies, the authors question the existence of gendered division of labor altogether. As a diverse group of hunter-gatherer experts, we find …

New Labor Curves Of Dilation And Station To Improve The Accuracy Of Predicting Labor Progress., Emily F Hamilton, Tilekbek Zhoroev, Philip A Warrick, Adi L Tarca, Thomas J Garite, Aaron B Caughey, Jason Melillo, Mona Prasad, Duncan Neilson, Peter Singson, Kimberlee Mckay, Roberto Romero

Women’s Health Articles

BACKGROUND: The diagnosis of failure to progress, the most common indication for intrapartum cesarean delivery, is based on the assessment of cervical dilation and station over time. Labor curves serve as references for expected changes in dilation and fetal descent. The labor curves of Friedman, Zhang et al, and others are based on time alone and derived from mothers with spontaneous labor onset. However, labor induction is now common, and clinicians also consider other factors when assessing labor progress. Labor curves that consider the use of labor induction and other factors that influence labor progress have the potential to be …

Call Me Dr Ishmael: Trends In Electronic Health Record Notes Available At Emergency Department Visits And Admissions, Brian W Patterson, Daniel J Hekman, Frank J Liao, Azita G Hamedani, Manish N Shah, Majid Afshar

Faculty, Staff and Student Publications

OBJECTIVES: Numerous studies have identified information overload as a key issue for electronic health records (EHRs). This study describes the amount of text data across all notes available to emergency physicians in the EHR, trended over the time since EHR establishment.

MATERIALS AND METHODS: We conducted a retrospective analysis of EHR data from a large healthcare system, examining the number of notes and a corresponding number of total words and total tokens across all notes available to physicians during patient encounters in the emergency department (ED). We assessed the change in these metrics over a 17-year period between 2006 and …

A C-Terminal Motif Containing A Pkc Phosphorylation Site Regulates Γ-Protocadherin-Mediated Dendrite Arborization In The Cerebral Cortex In Vivo., Camille M Hanes, Kar Men Mah, David M Steffen, Cathy M Mcleod, Charles G Marcucci, Leah C Fuller, Robert W. Burgess, Andrew M Garrett, Joshua A Weiner

Faculty Research 2024

The Pcdhg gene cluster encodes 22 γ-Protocadherin (γ-Pcdh) cell adhesion molecules that critically regulate multiple aspects of neural development, including neuronal survival, dendritic and axonal arborization, and synapse formation and maturation. Each γ-Pcdh isoform has unique protein domains—a homophilically interact- ing extracellular domain and a juxtamembrane cytoplasmic domain—as well as a C-terminal cytoplasmic domain shared by all isoforms. The extent to which isoform-specific versus shared domains regulate distinct γ-Pcdh functions remains incompletely understood. Our previous in vitro studies identified protein kinase C (PKC) phosphorylation of a serine residue within a shared C-terminal motif as a mechanism through which γ-Pcdh promotion …

Determinants Of Women’S Fertility Rates In The U.S., Kelle Bormann

Proceedings of the Jepson Undergraduate Conference on International Economics

Fertility rates have long been a subject of extensive research. In our constantly evolving world, economists have examined these rates across different times and regions to understand how cultural and economic factors influence women’s fertility. This paper analyzes historically significant factors to determine if their impact has changed over time, aiming to inform policies addressing the declining fertility trend. Data from the IPUMS USA 2021 census was used, estimated through a logit odds ratio regression with robust standard errors, and analyzed at the ten, five, and one percent significance levels. The findings indicate that the age of the youngest child …

Relative Numerosity Is Constructed From Size And Density Information: Evidence From Adaptation, Frank H. Durgin, Zahara Martinez , '23

Psychology Faculty Works

To dissociate aftereffects of size and density in the perception of relative numerosity, large or small adapter sizes were crossed with high or low adapter densities. A total of 48 participants were included in this preregistered design. To adapt the same retinotopic region as the large adapters, the small adapters were flashed in a sequence so as to “paint” the adapting density across the large region. Perceived numerosities and sizes in the adapted region were then compared to those in an unadapted region in separate blocks of trials, so that changes in density could be inferred. These density changes were …

Barley Grass And Its Management In Crops, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Barley grass is a common name for Hordeum glaucum and H. leporinum. Barley grass is a major crop weeds species because the seed is readily dispersed, it is renowned for rapidly germinating in autumn, and post-emergent herbicide control options are limited. It can also act as an alternate host for cereal diseases and can develop resistance to herbicides.

The rapid germination of the species after rainfall gives barley grass the potential to act as a green bridge for cereal root rot diseases

Wild Oat And Its Management In Crops, Department Of Primary Industries And Regional Development, Western Australia

Grains and other field crops factsheets

Wild oats (Avena fatua and A. ludoviciana) represent a large cost to cropping; they are highly competitive and when left uncontrolled, can reduce wheat yields by up to 80%.

The greatest yield loss occurs when wild oat plants emerge at the same time as the crop.

Managing Flystrike In Sheep, Department Of Primary Industries And Regional Development, Western Australia

Animal production and livestock factsheets

Flystrike is a significant health and welfare risk to Australian sheep and costs $280 million annually. Flystrike should be actively monitored and managed to prevent productivity losses and ensure good animal welfare.

Mixed-Methods Assessment Of Farmworkers’ Perceptions Of Workplace Compliance With Worker Protection Standards And Implications For Risk Perceptions And Protective Behaviors, Carly Hyland, Lisa Meierotto, Rebecca L. Som Castellano, Cynthia L. Curl

Public and Population Health Faculty Publications and Presentations

Introduction: The Environmental Protection Agency (EPA)’s Worker Protection Standards is the primary set of legislation aimed at protecting farmworkers from occupational pesticide exposure in the United States. Previous studies suggest that worker adoption of Pesticide Protective Behaviors (PPBs) promoted by WPS is associated with lower urinary pesticide concentrations. However, adoption of PPBs is often outside of the control of individual farmworkers and dependent on workplace factors such as employer provisioning of Personal Protective Equipment (PPE) and access to trainings/resources.

Methods: We conducted a mixed-method study including urinary pesticide biomonitoring, surveys, and interviews with 62 Latinx farmworkers in southwestern Idaho from …

Psychosocial And Mental Health Challenges Facing Perinatally Hiv-Infected Adolescents Along The Kenyan Coast: A Qualitative Inquiry Using The Socioecological Model, Stanley W. Wanjala, Moses Nyongesa, Stanley Luchters, Amina Abubakar

Institute for Human Development, East Africa

Background: The advent of antiretroviral therapy has led perinatally HIV-infected (PHI) adolescents to live long, fulfilling lives through lifelong treatment. However, there is limited knowledge about the lived experiences and psychosocial and mental health challenges faced by PHI adolescents in sub-Saharan Africa, where 80% of PHI adolescents reside. To address this gap, we adapted the socioecological model to investigate the challenges and lived experiences of PHI adolescents in rural coastal Kenya.

Methods: Between October and November 2018, a sample of 40 participants (20 PHI adolescents and their 20 primary caregivers) participated in a qualitative study using an H-assessment data collection …

Un-Barre-D: Decreasing Barriers To Participation For Individuals With Parkinson’S Using Ballet, Lauren Jew

Occupational Therapy Student Capstones

No abstract provided.

Open Educational Resources In Higher Education, Teisha Robertson

Alabama Libraries

Open Educational Resources (OERs) are materials such as books, articles, videos of lectures, and other resources provided to students free of charge. The increase in textbook costs has caused students to depend upon OERs. OERs are excellent teaching resources for students and instructors because they are free or low-cost and easy to adapt to instructor curricula. Furthermore, they can help students from low-income families save money. This paper will discuss the importance, challenges, and benefits of open educational resources in higher education institutions.

Multi-Omic Single-Cell Integration For Understanding T Cell Responses In Acute Myeloid Leukemia, Poonam Desai

Dissertations and Theses (Open Access)

In recent years, translational initiatives have gained significant traction within the medical community. Clinical parameters alone have been insufficient to fully understand the intricate mechanisms governing patient responses to disease and therapy. Additionally, single-cell technologies have rapidly advanced to a point where generation of large patient-based datasets is financially and logistically feasible. The integration of clinical information with multi-omic single-cell technologies enables the formation of data-driven hypotheses pertaining to the mechanisms of disease progression and therapeutic resistance. Acute Myeloid Leukemia (AML) is a rapidly-progressing cancer of the bone marrow with poor prognoses and dismal outcomes. Of the adult patients that …

In Situ Synthesis, Characterization And Photocatalytic Efficacy Of Silver-Enhanced Mxene And Graphene Nanocomposites, Kishore Chand, M. Mustafa Azeem, Muhammad Nazim Lakhan, Mukhtiar Ahmed, Muhammad Jehanzaib Aslam, Ahmer Hussain Shah

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

The emergence of 2D materials has significantly expanded the wide range of nanomaterials with diverse applications. Notably, their high conductivity, catalytic efficiency, and hydrophobicity have fueled heightened research interests for water treatment applications. This research aimed to investigate the synthesis and characterization of MXene and reduced graphene oxide (rGO) nanocomposites with silver nanoparticles (Ag) for enhanced catalytic activity in the decomposition of Direct Blue-24 dye. In this study, we employed well-established methods, previously documented in the literature, to prepare two distinct nanocomposites. Novel nanocomposites, namely reduced graphene oxide–silver nanoparticles (rGO–Ag) and MXene–silver nanoparticles (MXene–Ag), were synthesized using the hydrothermal and …

Five Side Populations Isolated From Rat Bone Marrow‑Derived Mesenchymal Stem Cells, Dalia Al Saied Moustafa Ahmed, Mahmoud Elhussiny Salama, Ahmed Abdou Emam, Sara Mohamed Farrag, Basma Hamed Othman, Shaimaa Hassan Haiba, Mohamed Mosaad Salama

Faculty Journal Articles

Over the past decade, there has been marked enthusiasm surrounding the potential application of mesenchymal stem cells (MSCs) as universally compatible donor cells in the field of regenerative medicine. Due to their distinctive immune-tolerant characteristics, these entities hold promise for potential applications in cell replacement, gene therapy and immunomodulatory therapy. MSCs have been defined and characterized based on adhesion properties and different surface markers that are negative for hematopoietic stem cells and positive for MSCs, and their capacity for differentiation into osteocyte, chondrocyte and adipocyte is observed under suitable circumstances. However, this protocol is costly and time-consuming and cannot confirm …

A Landscape Evaluation Of Caffeine Citrate Availability And Use In Newborn Care Across Five Low- And Middle-Income Countries, Osayame Ekhaguere, Olufunke Bolaji, Helen Nabwera, Andrew Storey, Nicholas Embleton, Stephen Allen, Zelalem Demeke, Olufunke Fasawe, Betty Wariari, Mansharan Seth

Centre of Excellence in Women and Child Health

Apnoea of prematurity (AOP) is a common complication among preterm infants (< 37 weeks gestation), globally. However, access to caffeine citrate (CC) that is a proven safe and effective treatment in high-income countries is largely unavailable in low- and-middle income countries, where most preterm infants are born. Therefore, the overall aim of this study was to describe the demand, policies, and supply factors affecting the availability and clinical use of CC in LMICs. A mixed methods approach was used to collect data from diverse settings in LMICs including Ethiopia, Kenya, Nigeria, South Africa, and India. Qualitative semi-structured interviews and focus group discussions were conducted with 107 different health care providers, and 21 policymakers and other stakeholders from industry. Additional data was collected using standard questionnaires. A thematic framework approach was used to analyze the qualitative data and descriptive statistics were used to summarize the quantitative data. The findings indicate that there is variation in in-country policies on the use of CC in the prevention and treatment of AOP and its availability across the LMICs. As a result, the knowledge and experience of using CC also varied with clinicians in Ethiopia having no experience of using it while those in India have greater knowledge and experience of using it. This, in turn, influenced the demand, and our findings show that only 29% of eligible preterm infants are receiving CC in these countries. There is an urgent need to address the multilevel barriers to accessing CC for managing AOP in Africa. These include cost, lack of national policies, and, therefore, lack of demand stemming from its clinical equivalency with aminophylline. Practical ways to reduce the cost of CC in LMICs could potentially increase its availability and use.

Removing Methane Via Atmospheric Oxidation Enhancement: The Legal Framework, Romany M. Webb, Martin Lockman, Korey Silverman-Roati

Sabin Center for Climate Change Law

To achieve the Paris Agreement’s goal of limiting the increase in global average temperatures to “well below 2 degrees Celsius,” and ideally 1.5 degrees Celsius, above pre-industrial levels, global greenhouse gas (“GHG”) emissions must reach net zero in the second half of the century. The global community is not currently on track to achieve net zero emissions. In fact, with the exception of a slight dip during the Covid-19 pandemic, emissions have risen steadily in recent years. This, together with the increasingly visible impacts of climate change, has prompted growing interest in the possibility of removing GHGs directly from the …

The Youth Tax In Parole Hearings, David M. N. Garavito, Amelia Hritz, John H. Blume

South Carolina Law Review

No abstract provided.