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Corrigendum To “Two New Species Of Inocybe (Inocybaceae: Agaricomycetes) From Türkiye Based On Morphological Characteristics And Phylogenetic Evidence [Turkish Journal Of Botany 48 (3) 2024 145-154 ], Oğuzhan Kaygusuz, Ditte Bandini, Henning Knudsen, Meike Piepenbring

Turkish Journal of Botany

This corrigendum is to address an issue regarding the manuscript's previous publication, specifically Fig. 5.Regrettably, the authors have noticed that the Figure 5 is missing among the figures although there is an incite reference within the text. To rectify this oversight and ensure the accuracy of the published work, the Figure 5 is included for your reference.

Link to the original article: https://journals.tubitak.gov.tr/botany/vol48/iss3/3/

The Evolution Of Bipedalism In Phylogenetic And Environmental Contexts, Yeganeh Sekhavati

Arts & Sciences Graduate Student Theses and Dissertations

Bipedalism is a key human adaptation, making its evolution a central topic in biological anthropology. To meet the mechanical demands of bipedalism, the human foot evolved significantly. This research examines the evolutionary patterns and selective histories that have shaped foot evolution in hominins and great apes. Additionally, it analyzes the environmental conditions under which hominin feet evolved. The results suggest that the last common ancestor of humans and chimpanzees exhibited adaptations for terrestrial heel strike plantigrady and vertical climbing. Early hominin foot adaptations involved eversion and midfoot stability. The Paranthropus and the Australopithecus africanus + A. sediba clades revealed arboreal …

Carbonate And Organic Proxies And The Impacts Of Climate On Lake Systems: Paleoclimate Interpretations From Lake Chalco, Mexico, Aria Holmes

Earth and Planetary Sciences ETDs

This project incorporates several lines of evidence to better understand the climate at Lake Chalco. Chapter 1 utilizes oxygen isotopes from carbonates and show that the Inter Tropical Convergence Zone varies on primarily glacial and millennial timescales; precession is not observed. These data indicate glacials periods were shallower and interglacials were wetter periods at Lake Chalco. Chapter 2 studies carbon, nitrogen, C/N, and TOC proxies and finds that the lake conditions during the glacials and interglacials are primarily a mixed algal-macrophyte-terrestrial organic matter. Deviations show that the lake during the interglacials had more algal organic matter- reflecting influxes of nutrients …

Sand, Ice, And X-Rays: Developing Xct Methods For Frozen Samples And Refining Siliciclastic Facies Models For Perennially Ice-Covered Lakes, Utilizing Cores From Lake Fryxell, Mcmurdo Dry Valleys, Antarctica, Holly M. Levett

Earth and Planetary Sciences ETDs

Sedimentation in perennially ice-covered lakes (PICLs) is proposed to be bi-modal, with mud deposited by stream inflow and sand deposited on the ice cover by aeolian processes and then melting through by absorption of solar radiation. Here, we consider Lake Fryxell, a PICL in the McMurdo Dry Valleys, and several lake bed cores about 30 cm in length, to better understand PICL facies through time, using micro X-ray CT (XCT). Using XCT images along with sieve and laser granulometry data, we constrained the grain-size of PICL deposits to dominantly medium / fine sand with a coarse component. The presence of …

27-Hydroxycholesterol Acts On Estrogen Receptor Α Expressed By Pomc Neurons In The Arcuate Nucleus To Modulate Feeding Behavior, Hui Ye, Xiaohua Yang, Bing Feng, Pei Luo, Valeria C Torres Irizarry, Leslie Carrillo-Sáenz, Meng Yu, Yongjie Yang, Benjamin P Eappen, Marcos David Munoz, Nirali Patel, Sarah Schaul, Lucas Ibrahimi, Penghua Lai, Xinyue Qi, Yuliang Zhou, Maya Kota, Devin Dixit, Madeline Mun, Chong Wee Liew, Yuwei Jiang, Chunmei Wang, Yanlin He, Pingwen Xu

Faculty, Staff and Students Publications

Oxysterols are metabolites of cholesterol that regulate cholesterol homeostasis. Among these, the most abundant oxysterol is 27-hydroxycholesterol (27HC), which can cross the blood-brain barrier. Because 27HC functions as an endogenous selective estrogen receptor modulator, we hypothesize that 27HC binds to the estrogen receptor α (ERα) in the brain to regulate energy balance. Supporting this view, we found that delivering 27HC to the brain reduced food intake and activated proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (POMCARH) in an ERα-dependent manner. In addition, we observed that inhibiting brain ERα, deleting ERα in POMC neurons, or chemogenetic inhibition of …

Monoallelic De Novo Ajap1 Loss-Of-Function Variants Disrupt Trans-Synaptic Control Of Neurotransmitter Release, Simon Früh, Sami Boudkkazi, Peter Koppensteiner, Vita Sereikaite, Li-Yuan Chen, Diego Fernandez-Fernandez, Pascal D Rem, Daniel Ulrich, Jochen Schwenk, Ziyang Chen, Elodie Le Monnier, Thorsten Fritzius, Sabrina M Innocenti, Valérie Besseyrias, Luca Trovò, Michal Stawarski, Emanuela Argilli, Elliott H Sherr, Bregje Van Bon, Erik-Jan Kamsteeg, Maria Iascone, Alba Pilotta, Maria R Cutrì, Mahshid S Azamian, Andrés Hernández-García, Seema R Lalani, Jill A Rosenfeld, Xiaonan Zhao, Tiphanie P Vogel, Herda Ona, Daryl A Scott, Peter Scheiffele, Kristian Strømgaard, Mehdi Tafti, Martin Gassmann, Bernd Fakler, Ryuichi Shigemoto, Bernhard Bettler

Faculty, Staff and Students Publications

Adherens junction–associated protein 1 (AJAP1) has been implicated in brain diseases; however, a pathogenic mechanism has not been identified. AJAP1 is widely expressed in neurons and binds to γ-aminobutyric acid type B receptors (GBRs), which inhibit neurotransmitter release at most synapses in the brain. Here, we show that AJAP1 is selectively expressed in dendrites and trans-synaptically recruits GBRs to presynaptic sites of neurons expressing AJAP1. We have identified several monoallelic AJAP1 variants in individuals with epilepsy and/or neurodevelopmental disorders. Specifically, we show that the variant p.(W183C) lacks binding to GBRs, resulting in the inability to recruit them. Ultrastructural analysis revealed …

Novelties In Funalia And The Status Of Fomitella (Polyporaceae, Basidiomycota), Virton Rodrigo Targino De Oliveira, Paulo Roberto De Assis Alves, Nelson Correia De Lima-Júnior, Carla Santos, Nelson Lima, Leif Ryvarden, Josef Vlasák, Tatiana Baptista Gibertoni

Turkish Journal of Botany

During studies on the taxonomical delimitation of some species of Funalia, some inconsistencies were observed in the genus. Based on morphological and phylogenetic analyses, Fomitella supina was positioned within the Funalia clade, thus the synonymization of the genus and the new combination of F. supina are proposed. Funalia glabrorigens is also combinated in the genus, while Coriolopsis hainanensis is suggested as a synonym of F. floccosa and F. rigida is assumed as a distinct species from F. floccosa. A table with morphological comparison of the 10 Funalia species confirmed by molecular analyses is also presented.

Otocolobus Manul (Carnivora: Felidae), Paula Noonan, Zoe Baker, Virginia Hayssen

Biological Sciences: Faculty Publications

Otocolobus manul (Pallas, 1776) is a small, solitary, terrestrial felid commonly called the Manul and is the sole species of its genus. It occurs in Afghanistan, Armenia, Bhutan, China, India, the Islamic Republic of Iran, Kazakhstan, Kyrgyzstan, Mongolia, Nepal, Pakistan, the Russian Federation, and Turkmenistan. Otocolobus manul might still occur in Tajikistan and Uzbekistan but might be extinct in Azerbaijan. As assessed in 2020, O. manul is listed as “Least Concern” (LC) on the International Union for Conservation of Nature and Natural Resources Red List of Threatened Species, with an estimate of 58,000 adults, although the population might be decreasing.

Essays On Health, Labor, And Development Economics, Md Mohsan Khudri

Electronic Theses and Dissertations Archive

In the first essay, using data from the Panel Study of Income Dynamics, I estimate the impact of breastfeeding initiation and duration on multiple cognitive, health, and behavioral outcomes spanning early childhood through adolescence. To mitigate the potential bias, I employ a doubly robust (DR) estimation method, addressing misspecification in either the treatment or outcome models while adjusting for selection effects. My novel approach is to use and evaluate a battery of supervised machine learning (ML) algorithms to improve propensity score (PS) estimates. I demonstrate that the gradient boosting machine algorithm removes bias more effectively and minimizes other prediction errors …

Onesamp 3.0: Estimation Of Effective Population Size Via Snp Data From One Population, Aaron Hong, Rebecca Cheek, Suhashi Nihara De Silva, Kingshuk Mukherjee, Isha Yooseph, Mark Heim, David Tallmon, Christina Boucher

Faculty, Staff, and Students

The genetic effective size (Ne) is arguably one of the most important characteristics of a population as it impacts the rate of loss of genetic diversity. Methods that estimate Ne are important in population and conservation genetic studies as they quantify the risk of a population being inbred or lacking genetic diversity. Yet there are very few methods that can estimate the Ne from data from a single population and without extensive information about the genetics of the population, such as a linkage map, or a reference genome of the species of interest. We present ONeSAMP 3.0, an algorithm for …

Mattiastrum Pulumurense (Cynoglossinae, Boraginaceae), A New Endemic Species From Türkiye, Asli Doğru Koca, Mustafa Gökmen, Gülderen Yilmaz, Mehmet Yavuz Paksoy

Turkish Journal of Botany

A new species, Mattiastrum pulumurense, has been described from Tunceli in eastern Turkey. It is generally distinguished from other species (except M. racemosum var. scabridum) by a sparsely hairy or glabrescent above-ground part. It is most similar morphologically to M. longipes, M. calycinum and Paracaryum hedgei (P. hedgei is potential a member of the genus Mattiastrum). However, it differs from M. longipes and M. calycinum by its 3-3.5 mm long and linear lanceolate scales, 2.5-4.5 mm long anthers, and 10-15 mm long styles; it differs from Paracaryum hedgei by its 3-3.5 mm long scales, 2.5-4.5 mm long anthers. In addition, …

Impact Of Containment And Elevation On Created Marsh Plant Community And Ecosystem Dynamics, Kevin R. Stoner

LSU Master's Theses

Coastal marsh restoration is increasing globally, as marshes are impacted by anthropogenic impacts. Billions of dollars are allocated to marsh restoration in the Mississippi River delta where wetland loss rates are extremely high. The recovery of structural and functional attributes of created marshes varies by attribute measured and project. Here, two marshes created in 2018 and one natural marsh were used to examine how variations in hydrologic connectivity and marsh elevation influence subsurface hydrology and salinity, vegetation community structure, soil properties, accretion, and denitrification. I established a comparative field study in a created marsh contained within a higher elevation containment …

Revisiting Fr13a For Submergence Tolerance: Beyond The Sub1a Gene, Waseem Hussain, Mahender Anumalla, Abdelbagi M. Ismail, Harkamal Walia, Vistas Kumar Singh, Ajay Kohli, Sankalp Bhosale, Hans Bhardwaj

Department of Agronomy and Horticulture: Faculty Publications

Rice landrace FR13A is the original donor of the SUB1A gene. FR13A harbors hidden genetic variation that surpasses the submergence tolerance level of SUB1A. Here, we provide an overview of the unique features of FR13A associated with exceptional recovery ability that have been overlooked since the significant discovery of the SUB1 locus. We present a detailed overview of how to underpin the new genes associated with the recovery ability seen in FR13A. Finally, we propose a unique approach to develop rice cultivars that surpass submergence tolerance beyond the SUB1 locus from FR13A.

Functional And Structural Analysis Of The Neimann-Pick Disease Type C Pathway To Include Caveolin-1, Anthony Michael Seat

Chemistry and Chemical Biology ETDs

Human disease is often thought of as an all or nothing prospect, either one has the disease or one does not. This does not bear out in clinical or personal experiences, instead demonstrating that disease occurs within a spectrum ranging from presumed unaffected to demonstrably and detrimentally affected.Neimann-Pick disease is one example of this spectrum look into diseased states, with multiple named versions of a phenotypically similar disease. We focus on Neimann-Picktype C (NPC), which is the result of a disruption in the efflux of cholesterol and sphingolipids from the endocytic pathway. NPC demonstrates this concept of a spectrum of …

Chemical And Physical Properties Of Fine Fractions From A Village Proximate To A Uranium Mine: Insights About Soil Health, Mary P. Haley

Nanoscience and Microsystems ETDs

Thousands of abandoned uranium mines (AUM) in Native American tribal lands have not been fully remediated, leaving uranium mine wastes exposed and accessible for potential erosion and transport by wind. Analyzing the metal and organic content of the fine-grained fractions in soils could uncover the impact of mine legacy on the soil health in communities that live in proximity to AUM. This study investigates the physical and chemical properties of the fine-grained fraction (μm) of soils to quantify the effect of heavy metal-bearing particulates on the soil health in the village of Paguate and within the Jackpile-Paguate AUM located on …

Dansyl Fluorophore Functionalized Hierarchically Structured Mesoporous Silica Nanoparticles As Novel Latent Fingerprint Development Agents, Lais F A M Oliveira, Lais V A T Da Silva, Artur F Sonsin, Meclycia S Alves, Cristiane V Costa, Jeane C S Melo, Nicholas Ross, Paul T Wady, Thomas Zinn, Ticiano G Do Nascimento, Eduardo J S Fonseca, Alexandro M L De Assis, A Robert Hillman, Adriana S Ribeiro

Faculty, Staff and Student Publications

A nanostructured hybrid material based on mesoporous silica nanoparticles (MCM-41) functionalized with chitosan and a fluorescent dye (dansylglycine), designated MCM-41@Ch@DnsGly, was synthesized and characterized with a view to its application for the visualization of latent fingerprints. These nanoparticles were applied as latent fingerprint developers for marks on surfaces of diverse chemical composition, topography, optical characteristics, and spatially variant nature, typical of forensically challenging evidence. For quality assessment of the enhanced fingermarks, the developed images were analyzed holistically using the UK Home Office scale, forensic protocols and, in terms of their constituent features (minutiae), using forensic software. Across a substantive collection …

Multiparametric Mri-Based Radiomic Models For Early Prediction Of Response To Neoadjuvant Systemic Therapy In Triple-Negative Breast Cancer, Rania M Mohamed, Bikash Panthi, Beatriz E Adrada, Medine Boge, Rosalind P Candelaria, Huiqin Chen, Mary S Guirguis, Kelly K Hunt, Lei Huo, Ken-Pin Hwang, Anil Korkut, Jennifer K Litton, Tanya W Moseley, Sanaz Pashapoor, Miral M Patel, Brandy Reed, Marion E Scoggins, Jong Bum Son, Alastair Thompson, Debu Tripathy, Vicente Valero, Peng Wei, Jason White, Gary J Whitman, Zhan Xu, Wei Yang, Clinton Yam, Jingfei Ma, Gaiane M Rauch

Faculty, Staff and Student Publications

Triple-negative breast cancer (TNBC) is often treated with neoadjuvant systemic therapy (NAST). We investigated if radiomic models based on multiparametric Magnetic Resonance Imaging (MRI) obtained early during NAST predict pathologic complete response (pCR). We included 163 patients with stage I-III TNBC with multiparametric MRI at baseline and after 2 (C2) and 4 cycles of NAST. Seventy-eight patients (48%) had pCR, and 85 (52%) had non-pCR. Thirty-six multivariate models combining radiomic features from dynamic contrast-enhanced MRI and diffusion-weighted imaging had an area under the receiver operating characteristics curve (AUC) > 0.7. The top-performing model combined 35 radiomic features of relative difference between …

Development Of Peptidomimetics Based On Γ-Aapeptide Molecular Scaffolds To Modulate Amyloid Peptide Aggregation, Heng Liu

USF Tampa Graduate Theses and Dissertations

Many proteins contain fragments that become structured upon binding to specific targets or through self-association. Notable examples of such disorder-to-order transitions include amyloidogenic proteins like amyloid-β peptide (Aβ) and tau peptide in Alzheimer's disease, α-Synuclein in Parkinson's disease, and hIAPP in type 2 diabetes, and so on. These regions can aggregate into amyloid fibrils through β -sheet stacking, contributing to amyloidosis and related diseases. Although direct link between amyloid formation and neurodegenerative disease development is not fully understood, developing effective inhibitors of these amyloid peptides remains promising both for fundamental research and therapeutical advance.

We have developed a new class …

Lymphoid Tissues Contribute To Plasma Viral Clonotypes Early After Antiretroviral Therapy Interruption In Siv-Infected Rhesus Macaques, Antonio Solis-Leal, Nongthombam Boby, Suvadip Mallick, Yilun Cheng, Fei Wu, Grey De La Torre, Jason Dufour, Xavier Alvarez, Vinay Shivanna, Yaozhong Liu, Christine M. Fennessey, Jeffrey D. Lifson, Qingsheng Li, Brandon F. Keele, Binhua Ling

School of Biological Sciences: Faculty Publications

The rebound-competent viral reservoir, composed of a virus that is able to persist during antiretroviral therapy (ART) and mediate reactivation of systemic viral replication and rebound viremia after ART interruption (ATI), remains the biggest obstacle to treating HIV infection. A better understanding of the cellular and tissue origins and the dynamics of viral populations that initiate rebound upon ATI could help develop therapeutic strategies for reducing the rebound-competent viral reservoir. In this study, barcoded simian immunodeficiency virus (SIV), SIVmac239M, was used to infect rhesus macaques to enable monitoring of viral barcode clonotypes contributing to virus detectable in plasma after ATI. …

Cover And Contents

Turkish Journal of Botany

No abstract provided.

Role Of Sds-22/Pp1 Phosphatase In Polarizing The Germplasm Of Caenorhabditis Elegans Embryo, Aparna Nurni Ravi

Dartmouth College Ph.D Dissertations

During asymmetric cell division, cell polarity and cell cycle are tightly coupled to ensure robust segregation of cell fate determinants and generation of cellular diversity. In the one-cell C. elegans embryo, multiple cell cycle kinases regulate cell polarization and posterior segregation of germline fate determinants (germplasm). For example, PLK-1 kinase inhibits the retention of its germplasm substrate POS-1 in the anterior, driving POS-1 segregation to the posterior (Han et al., 2018). Additionally, MBK-2 kinase disassembles P granules in the anterior through phosphorylation of the P granule scaffold MEG-3, helping to drive P granule segregation to the posterior (Wang et al., …

Patient-Reported Quality Of Life At Diagnosis In Adolescent And Young Adults With Cancer, Goldy C George, Clark Andersen, Xiaohui Tang, Elizabeth Rodriguez, Midhat Jafry, Maria C Swartz, Sairah Ahmed, Carlos H Barcenas, J Andrew Livingston, Michael E Roth, Michelle A T Hildebrandt

Faculty, Staff and Student Publications

Background: The overall landscape of health-related quality of life (HRQoL) has not been thoroughly investigated in adolescents and young adults (AYAs) with cancer. Data are also lacking on how well HRQoL at the time of cancer diagnosis can prognosticate long-term survival in AYA survivors.

Patients and methods: We included 3,497 survivors of AYA cancer (age 15-39 years at diagnosis) who completed the Short-Form 12 Health Survey (SF-12) HRQoL questionnaire at diagnosis. Physical component summary (PCS) and mental component summary (MCS) scores were generated, with scores < 50 representing poor HRQoL. Differences in HRQoL by patient characteristics and tumor type were investigated using violin plots and t tests/analysis of variance. The effect of HRQoL on overall survival was assessed using Kaplan-Meier plots and Cox proportional hazards models.

Results: Overall mean PCS and MCS scores in this racially/ethnically diverse cohort (64% White, 19% …

Faculty’S Role In Creating A (Remote) Sense Of Community Among Faculty And Facilitating Contexts Of Care For Students, Jesus R. Nunez, Jesus Cisneros, Isela Pena

Higher Learning Research Communications

Objectives: This qualitative study employed a sensemaking approach to understand faculty members’ sensemaking of their roles during the COVID-19 pandemic and the emergency transition to remote teaching and learning.

Methods: An email invitation to participate in the study was sent to faculty who taught in an MBA program during both the 2019–2020 and 2020–2021 academic school years. Data were collected through in-depth, semi-structured interviews with 14 faculty members who self-selected to participate in the study.

Results: Two salient themes emerged from the research: creating a (remote) sense of community among faculty and facilitating contexts of care for students. These …

Learning To Express Reward Prediction Error-Like Dopaminergic Activity Requires Plastic Representations Of Time, Ian Cone, Claudia Clopath, Harel Z Shouval

Faculty, Staff and Student Publications

The dominant theoretical framework to account for reinforcement learning in the brain is temporal difference learning (TD) learning, whereby certain units signal reward prediction errors (RPE). The TD algorithm has been traditionally mapped onto the dopaminergic system, as firing properties of dopamine neurons can resemble RPEs. However, certain predictions of TD learning are inconsistent with experimental results, and previous implementations of the algorithm have made unscalable assumptions regarding stimulus-specific fixed temporal bases. We propose an alternate framework to describe dopamine signaling in the brain, FLEX (Flexibly Learned Errors in Expected Reward). In FLEX, dopamine release is similar, but not identical …

A Hybrid Epithelial/Mesenchymal State In Head And Neck Cancer: A Biomarker For Survival With Differential Prognosis By Self-Reported Race, Angela L Mazul, Thomas F Barrett, Graham Colditz, Anuraag S Parikh, Salma Ramadan, Jose P Zevallos, Jason T Rich, R Alex Harbison, Ryan S Jackson, Patrik Pipkorn, Paul Zolkind, Itay Tirosh, Sidharth V Puram

2020-Current year OA Pubs

BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the 6

METHODS: Given the overlap in gene expression between hybrid E/M malignant cells and cancer-associated fibroblasts, we utilized deconvolution of bulk RNA sequencing data from oral cavity and laryngeal squamous cell carcinoma tumors from The Cancer Genome Atlas. We utilized our previously collected single-cell profiles to generate inferred malignant profiles and then scored these for hybrid E/M. We then conducted a survival analysis on overall and disease-free survival among self-reported Black and White Americans.

FINDINGS: The hybrid E/M state was differentially associated with head and neck cancer survival by self-reported …

Pulmonary Osteoclast-Like Cells In Silica Induced Pulmonary Fibrosis, Yoshihiro Hasegawa, Steven L Teitelbaum, Et Al.

2020-Current year OA Pubs

The pathophysiology of silicosis is poorly understood, limiting development of therapies for those who have been exposed to the respirable particle. We explored mechanisms of silica-induced pulmonary fibrosis in human lung samples collected from patients with occupational exposure to silica and in a longitudinal mouse model of silicosis using multiple modalities including whole-lung single-cell RNA sequencing and histological, biochemical, and physiologic assessments. In addition to pulmonary inflammation and fibrosis, intratracheal silica challenge induced osteoclast-like differentiation of alveolar macrophages and recruited monocytes, driven by induction of the osteoclastogenic cytokine, receptor activator of nuclear factor κΒ ligand (RANKL) in pulmonary lymphocytes, and …

Thermodynamic Coupling Of The Tandem Rrm Domains Of Hnrnp A1 Underlie Its Pleiotropic Rna Binding Functions, Jeffrey D Levengood, Davit Potoyan, Srinivasa Penumutchu, Abhishek Kumar, Qianzi Zhou, Yiqing Wang, Alexandar L Hansen, Sebla Kutluay, Julien Roche, Blanton S Tolbert

2020-Current year OA Pubs

The functional properties of RNA binding proteins (RBPs) require allosteric regulation through interdomain communication. Despite the importance of allostery to biological regulation, only a few studies have been conducted to describe the biophysical nature by which interdomain communication manifests in RBPs. Here, we show for hnRNP A1 that interdomain communication is vital for the unique stability of its amino-terminal domain, which consists of two RNA recognition motifs (RRMs). These RRMs exhibit drastically different stability under pressure. RRM2 unfolds as an individual domain but remains stable when appended to RRM1. Variants that disrupt interdomain communication between the tandem RRMs show a …

Genetic And Multi-Omic Resources For Alzheimer Disease And Related Dementia From The Knight Alzheimer Disease Research Center, Maria Victoria Fernandez, Menghan Liu, Aleksandra Beric, Matt Johnson, Arda Cetin, Maulik Patel, John Budde, Pat Kohlfeld, Kristy Bergmann, Joseph Lowery, Allison Flynn, William Brock, Brenda Sanchez Montejo, Jen Gentsch, Nicholas Sykora, Joanne Norton, Jen Gentsch, Olga Valdez, Priyanka Gorijala, Jessie Sanford, Yichen Sun, Ciyang Wang, Dan Western, Jigyasha Timsina, Tassia Mangetti Goncalves, Anh N Do, Yun Ju Sung, Guoyan Zhao, John C Morris, Krista Moulder, David M Holtzman, Randall J Bateman, Celeste Karch, Jason Hassenstab, Chengjie Xiong, Suzanne E Schindler, Joyce Joy Balls-Berry, Tammie L S Benzinger, Richard J Perrin, Andrea Denny, B Joy Snider, Susan L Stark, Laura Ibanez, Carlos Cruchaga

2020-Current year OA Pubs

The Knight-Alzheimer Disease Research Center (Knight-ADRC) at Washington University in St. Louis has pioneered and led worldwide seminal studies that have expanded our clinical, social, pathological, and molecular understanding of Alzheimer Disease. Over more than 40 years, research volunteers have been recruited to participate in cognitive, neuropsychologic, imaging, fluid biomarkers, genomic and multi-omic studies. Tissue and longitudinal data collected to foster, facilitate, and support research on dementia and aging. The Genetics and high throughput -omics core (GHTO) have collected of more than 26,000 biological samples from 6,625 Knight-ADRC participants. Samples available include longitudinal DNA, RNA, non-fasted plasma, cerebrospinal fluid pellets, …

Giardiasis: A Review Study In Iraq, Sarah Kamal Naser

Al-Ameed Journal for Medical Research and Health Sciences

Background: Giardia lamblia is the parasite that causes giardiasis, small intestine infection can result in severe issues and persistent symptoms, especially in children, giardiasis is a common diarrheal disease that can affect anyone everywhere in the world. It may not show any signs at all or it may result in symptoms like intermittent flatulence or persistent malabsorption, Giardia antigen  test,  molecular test for the presence of parasite DNA in feces, and identification of the organism in fresh stool or duodenal contents are all methods of diagnosis.

Aims: Finding the prevalence of giardiasis among cities is the purpose of this review …

A Rehabilitation Of The Body As Home: Reconstructing Young’S Feminist Phenomenology, Amanda Nicole C. Collantes

Budhi: A Journal of Ideas and Culture

This essay investigates Iris Marion Young’s account of female bodily experience and reconstructs her feminist phenomenology with the aim of reinterpreting and enriching the tradition of embodiment using feminist critique. It offers a clearer, more cohesive reconstruction of Young’s phenomenology by referencing three essays where she considers a particular aspect of women’s lived bodily experiences. It considers three recurring themes that appear in and are developed in the three main essays by Young referred to throughout the study. It presents personal, lived experience as political, thus encouraging social cooperation and women’s solidarity through collective meaning-making and a recovery of our …