Digital Commons Network^™

Leveraging The Genomic Tools To Explore The Molecular Basis Of Salinity Tolerance In Rice And Soybean, Rajat Pruthi

LSU Doctoral Dissertations

Salinity stress significantly challenges agricultural productivity, particularly affecting major crops like rice and soybean. This research investigates the genetic basis of salt tolerance in both crops through high-resolution genetic mapping, genome-wide association studies (GWAS), and RNA-Seq analysis. In rice, we examined quantitative trait loci (QTLs) associated with salt tolerance at the seedling and flowering stages using a population of advanced backcrossed introgression lines (ILs). A genetic map, constructed with 14,230 polymorphic SNP markers, identified distinct QTLs and candidate genes for salt tolerance at both stages, suggesting differential genetic controls. Notable genes such as OsHAK13 and OsCYP21-4 were upregulated under salt …

Elementary Science Teachers' Experiences: A Case Study On The Use Of Science+Cyber Curriculum, Laurie Salvail

LSU Doctoral Dissertations

The field of science education in the United States has undergone a major reform since 2015. A little more than twelve years ago, work began on constructing a framework for elementary, middle, and high school science education. This framework emphasized the shift from science being merely a memorization of facts to experiences that include science and engineering practices applied through crosscutting concepts and focused on core ideas in the field of science. With new standards teachers also have to overcome a) not having adequate time available to devote to science instruction b) lack of updated instructional materials aligned to the …

The Role Of Sexual Network Core Groups In Disease Epidemics, Jason Janeaux

LSU Doctoral Dissertations

Sexually transmitted infections (STIs) remain an economic and social burden, non-discriminately affecting sexually active individuals worldwide. The unique transmission of STIs is dependent upon host and pathogen life histories, as well as the underlying network structure of the host population. Within a population there is a group of individuals, the core group, that maintains STI presence and helps sustain ongoing transmission both within the core group and in the surrounding population. While the presence of these core groups is well documented, the criteria for inclusion into a sexual core group is not. In this dissertation, I explore common factors that …

Effect Of Air Filtration On Water Quality During Atmospheric Water Harvest In The Southwest United States, A.J. Barney

Civil Engineering ETDs

Access to sustainable drinking water is a concern across the globe. Atmospheric water harvest (AWH) offers a potential supplemental drinking water source. However, the sources and processes affecting AWH water quality are not well understood and must be thoroughly studied to consistently utilize AWH for drinking water. The objective of this research is to assess how removing particulate matter (PM) 2.5 and PM10 in the air used to produce AWH with air-filters affects the water quality of AWH. AWH samples were collected simultaneously with three identical dehumidifiers, utilizing three different air-filter configurations (no-filter, MERV8, and MERV12) in Albuquerque, NM from …

A Cultural Responsiveness Model To Support Parent's Practices In Families With Autistic Children: A Culturally Relevant Self- Compassion Program For Nigerian Mothers, Ekene Anastesia Odumegwu

Individual, Family, and Community Education ETDs

The goal of this intervention of self-compassion, mindfulness, and self-kindness focuses on training Nigerian mothers raising autistic children to enhance their psychological well-being. The intervention will assist Nigeran mothers living in Nigeria with developing their self- compassion. Building resilience for Nigerian mothers' self-compassion will help them to improve their physical and psychological health by becoming more mindful of their own pains and suffering when raising their child with Autism. Also, the proposed intervention will help Nigerian mothers to focus their attention and energy on how ways that might reduce the trauma and challenges experienced in parenting children with autism.

This …

A Phenomenological Exploration Of Language Shift Of Ikalanga In Botswana: Implications For Language Revitalization, Annah Sephene Macha

Language, Literacy, and Sociocultural Studies ETDs

This study explores the phenomenon of language shift among the Bakalanga community in Botswana, focusing on the gradual displacement of the iKalanga language by dominant languages such as Setswana and English that hold official status for education and broader communication. iKalanga faces significant challenges, as minority languages face extinction globally, the Bakalanga’s experience reflects broader trends where dominant languages supplant indigenous ones in education and wider communication. This research employed a phenomenological approach to investigate how the Bakalanga transmit knowledge amidst this language shift. Data was collected through focus groups, life history narratives, documents, and individual interviews, and analyzed using …

Insight Into Complexity: Novel Information Theoretic Analysis Of Spatiotemporal Interactions, Humayra Tasnim

Computer Science ETDs

Complex systems are comprised of different components. Interactions and associations among these components define the functionality of the system. For example, T cells must directly interact with virally infected cells to kill them. This research characterizes the most relevant components of complex systems by analyzing interacting relationships using information theoretic measures. It emphasizes the importance of spatial and temporal dynamics, which occur when components share spatial proximities or temporal sequences. Novel information theoretic analyses are proposed for quantifying the degree of association among system components, which is key to defining the spatiotemporal dynamics. One focus of this work is the …

Kinetic Characterization And Identification Of Key Active Site Residues Of The L-Aspartate N-Hydroxylase, Cree, Sydney B. Johnson, Hannah Valentino, Pablo Sobrado

Chemistry Faculty Research & Creative Works

CreE is a flavin-dependent monooxygenase (FMO) that catalyzes three sequential nitrogen oxidation reactions of L-aspartate to produce nitrosuccinate, contributing to the biosynthesis of the antimicrobial and antiproliferative natural product, cremeomycin. This compound contains a highly reactive diazo functional group for which the reaction of CreE is essential to its formation. Nitro and diazo functional groups can serve as potent electrophiles, important in some challenging nucleophilic addition reactions. Formation of these reactive groups positions CreE as a promising candidate for biomedical and synthetic applications. Here, we present the catalytic mechanism of CreE and the identification of active site residues critical to …

Antitumor Activity Of A Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting Lgr5 In Preclinical Models Of Neuroblastoma, Jianghua Tu, Yukimatsu Toh, Adela M Aldana, Jake J Wen, Ling Wu, Joan Jacob, Li Li, Sheng Pan, Kendra S Carmon, Qingyun J Liu

Faculty, Staff and Student Publications

Neuroblastoma (NB) is a cancer of the peripheral nervous system found in children under 15 years of age. It is the most frequently diagnosed cancer during infancy, accounting for ~12% of all cancer-related deaths in children. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) is a membrane receptor that is associated with the primary tumor formation and metastasis of cancers in the gastrointestinal system. Remarkably, high levels of LGR5 are found in NB tumor cells, and high LGR5 expression is strongly correlated with poor survival. Antibody-drug conjugates (ADCs) are monoclonal antibodies that are covalently linked to cell-killing cytotoxins to deliver the payloads …

The Borders Of Embodiment: Transgression, Transformation, And Corporeality In Chicanx Speculative Fiction, Chrysta Carson Wilson

English Language and Literature ETDs

This dissertation develops a clearer vision of Chicanx Speculative Fiction (SF) as its own genre anchored to the experiences and histories of the Chicanx community, with a particular interest in the avenues through which race and gender shape the experience of embodiment. SF resists hegemonic narratives that justify racial hierarchies and reveals both the cultural and concrete pressures exerted on Chicanx bodies in the United States as a minoritized and often exploited community. Furthermore, my analysis illustrates that Chicanx writers utilize elements of SF to defamiliarize traditional notions of race, class, and nationality. Through the use of defamiliarization, Chicanx SF …

An Investigation Of The Sub-Lethal Impacts To Pollinators From Pesticides, Emily Beahm

Theses

In order to feed a growing global population, agricultural practices must utilize pesticides to maintain high yields. Responsible use of pesticides should be based on literature confirming their efficacy and safety. When pesticides are not adequately investigated prior to their release, there can be severe consequences. Many highly effective pesticides, such as the class neonicotinoids, were allowed to be used commercially prior to thorough assessment of their environmental risks, resulting in consequences that largely have fallen to the exposed pollinator populations. To avoid similar outcomes, I tested the popular biopesticide Botanigard which contains Beauveria bassiana, an entomopathogenic fungus previously exposed …

The Early Proclamation Of The Resurrection As A Compelling Evidence For The Historicity Of The Resurrection: A Historical Inquiry Of The Resurrection Miracle, Marina Gordo Lyle

Masters Theses

The resurrection's historicity has been mainly defended through Jesus's empty tomb and postmortem appearances, which testify more to the resurrection belief of the first Christians than to the resurrection as a historical fact. The early proclamation of the resurrection is a minimal fact often overlooked when defending the resurrection's historicity. Nevertheless, it forms a compelling case for the resurrection as a historical fact through a type of proclamation that emerged at Pentecost, with immediate effects best explained by Jesus's resurrection. Indeed, Pentecost's effects in time include the church's birth and rapid expansion through miracles that only took place once the …

Emerging Trends And Challenges Of Metadata In 21st Century Nigerian Academic Libraries, Rose Ezeibe Dr., Daniel Aniekan Aloysius Dr., Godwin M. Nna-Etuk Dr.

Library Philosophy and Practice (e-journal)

This paper examined emerging trends and challenges of metadata in 21^st century Nigerian academic libraries. It gave the historical development of metadata and types of library metadata. The functions of metadata in academic libraries were accentuated. Bibliographic Framework (BibFrame) 2.0, Resource Description and Access, Functional Requirements for Bibliographic Records (FRBR) and Functional Requirement for Authority Data (FRAD) were identified as emerging trends of metadata in Nigerian academic libraries. The different online union catalogue and integrated library systems were analyzed. The various challenges and ways of addressing the application of metadata in Nigerian academic libraries were identified. The paper concluded …

Using Duckweed As A Green Manure, Nicholas Gosling

UNH Today Archive

No abstract provided.

Physical Activity, Sleep, And Depressive Symptoms Among Cognitively Impaired Older Adults Without Dementia, Debbie Chung

ETD Collection

Depressive symptoms are commonly experienced by older adults experiencing cognitive decline or dementia symptoms. Research is sparse in understanding modifiable drivers of depression among older adults with or without dementia. The current study examines the interplay between insomnia, physical activity, and depressive symptoms among cognitively impaired individuals without dementia. We performed a hierarchical regression analysis to investigate these relationships using the Health and Retirement Study (n=1208). Depressive symptoms and insomnia are based on the self-report, and a negative binomial model to evaluate these relationships with incidence rate ratios (IRRs) and 95% confidence intervals examined this interaction. Holding everything else constant, …

An Alcohol-Related Liver Disease Multi-Stakeholder Hub (Arms-Hub) To Enhance Research Activity In Underserved Communities In The Uk, Ashwin Dhanda, Victoria Allgar, Neeraj Bhala, Lynne Callaghan, Joana Castro, Shilpa Chokshi, Amanda Clements, Wendy Clyne, Colin Drummond, Ewan Forrest, Lesley Manning, Richard Parker, Debbie Shawcross, Jennifer Towey

Peninsula Medical School

Background: Alcohol use is the third leading risk factor of death and disability in the UK and costs the NHS £3.5 billion per year. Despite the high prevalence and healthcare burden of Alcohol-related Liver Disease (ArLD), there has been minimal research addressing prevention, morbidity and mortality. Reasons for this include stigma and lack of interest from public, charitable and commercial funding bodies. The objectives of this project were to identify and develop interdisciplinary partnerships, to explore stigma in ArLD, to develop a representative Patient and Public Involvement and Engagement (PPIE) group, to build research capacity, and to develop interdisciplinary research …

Psychological Profile Of Brazilian Jiu-Jitsu Athletes, Leandro De Lorenco-Lima

Doctoral Dissertations and Projects

Martial arts and combat sports have been shown to influence several desirable psychological factors positively. This quantitative study aimed to explore the differences in mental strength, resilience, grit, self-efficacy, self-control, aggression, life satisfaction, and mental health between belt ranks in Brazilian Jiu-Jitsu (BJJ) athletes. A sample of 410 BJJ participants (323 males and 87 females) from 18 to 60 years of age was included in this study. Data was collected anonymously via Google Form and included the Mental Strength Scale, Brief Resilience Scale, Grit Scale, General Self-Efficacy Scale, Brief Self-Control Scale, Brief Aggression Questionnaire, Satisfaction with Life Scale, Mental Health …

Predicting Loyalty & Leadership: Personalities Prone To Leadership, Length Of Service, & How Religiosity Plays A Part, Michael Joseph Camire

Doctoral Dissertations and Projects

This quantitative study was designed to examine whether relationships exist between personality type and religiosity, with leadership and organizational commitment. The connection between these variables has not been previously explored. The purpose of researching these variables was to enhance the field's knowledge surrounding the employee selection process as well as human resources development practices for organizations of all types and in all cultures. Study participants provided information on personality, religiosity, and employment and the data was evaluated to see if a statistically significant relationship existed. The study found statistically significant evidence to support that individuals with religion in their lives …

Recovering Christian Women Self-Care And Mentorship: A Qualitative Study, Clara Graves Hopkins

Doctoral Dissertations and Projects

The purpose of this qualitative study was to describe Christian women in recovery's experiences serving as a mentor to other addicts in Florida. This heuristic phenomenological qualitative research study aimed to understand the phenomenon of recovering Christian women how they function in their various roles as ministers, leaders, and mentors, and what they do for psychological and physical self-care when faced with challenges and barriers in society, why they are employed as ministers, counselors, and therapists who promote positive wellbeing and provide support in the success of recovery from addiction, trauma, and psychological issues, and how they maintain mental, emotional, …

A Phenomenological Study Of Dialectical Behavior Therapy In Special Education Classrooms, Ashley Deluccia

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to describe experiences of dialectical behavior therapy for special education teachers at a large, suburban school district in the Southeast United States. The theory guiding this study was Bandura's social cognitive theory (SCT), as it explains how new behaviors are learned and acquired. The central research question was: What are special education teachers' experiences of dialectical behavior therapy at a suburban school district in the Southeast United States? This qualitative design utilizes a phenomenological method. The sample included 12 special education teachers in behavior classrooms receiving dialectical behavior therapy. The setting was …

A Phenomenological Study Of The Experiences Of College Graduates With Chronic Illnesses Who Faced Health Threats And Interruptions In Their Daily Activities, Paula J. Uzuka

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to examine the experiences of individuals with chronic illnesses who graduated from college while facing health threats that often interrupted their daily activities. The theory that guided this study was Bandura's self-efficacy theory. Bandura defined self-efficacy as what a person understands about their ability to accomplish specific goals. In addition, Leventhal's construct, the common-sense model of self-regulation, provided the substructure of Bandura's theory, illustrating that with the right guidance, individuals can make decisions and manage their own health. An individual can use the theory and model to determine the necessary actions to …

Identifying Delirium In Hospitalized Patients Using Nursing Delirium Screening Scale, Christina S. Arockiam

Dissertations

Delirium is a sudden brain dysfunction that can affect the mental status of hospitalized adult patients. At the project site, there was no consistent screening tool for delirium, so an evidence-based solution was sought. The purpose of this quality improvement project was to determine if the translation of Heinrich et al.'s research regarding Gaudreau et al.'s Nursing Delirium Screening Scale (Nu-DESC) would impact the identification of delirium and subsequent provider notification within 30 minutes among adult patients in an acute care hospital in urban California over eight weeks. Virginia Henderson's need theory and the Iowa Model Revised: Evidence-based practice to …

To Resist Or Persist? An Examination Of Interpersonal Relationships Formed In Prison, Kamecia S. Blake

Walden Dissertations and Doctoral Studies

Prison is an important component of the criminal justice system. The structure and functionality of prison is tailored towards incapacitation, rehabilitation, and deterrence, which are goals of punishment. However, prison can have unintended consequences which increase the criminogenic risk of offenders causing inmates to become career criminals. This study examined the role of prison socialization, particularly the influence of interpersonal relationships formed while incarcerated on recidivistic behavior. It is important to investigate interpersonal relationships formed while incarcerated so that prison administrators can better realize its goal to rehabilitate offenders and prepare them for reintegration into society. The study was grounded …

How Sarcoidosis Mental Health Stories Could Affect Legislation, Dorothy Michelle Kemp

Walden Dissertations and Doctoral Studies

The problem this general qualitative study with narrative techniques addressed was the lack of empirical research about sarcoidosis mental health based on depression, anxiousness, and feeling lonely. Sarcoidosis legislation was also compared to current mental health legislation, which proposed mental health measures. This study aimed to gather secondary data of firsthand descriptions based on the impacts of sarcoidosis mental health aspects and review sarcoidosis legislation. Accumulated secondary data for this study were a collection of stories from doctors, diagnosed patients, and caregivers based on their narrative of the disease from a mental health perspective. In utilizing the advocacy coalition framework, …

High School Teachers’ Perceptions Of The Use Of Achieve3000 As A Literacy Proficiency Intervention, Cameron Ashley Gaines

Walden Dissertations and Doctoral Studies

The problem that was addressed through this study was that inconsistency in using a literacy development initiative resulted in no improvement of low literacy scores in April of 2022, as a total of 80.85% of high school students in one learning zone within a Georgia school district scored below literacy proficiency on the Georgia Milestones Assessment System. The purpose of this qualitative study was to examine high school teachers’ perceptions of the use of Achieve3000 as a literacy intervention using the conceptual framework of disciplinary literacy. This study's two research questions focused on high school teachers’ perceptions of using Achieve3000 …

Nrg Oncology And Particle Therapy Co-Operative Group Patterns Of Practice Survey And Consensus Recommendations On Pencil-Beam Scanning Proton Stereotactic Body Radiation Therapy And Hypofractionated Radiation Therapy For Thoracic Malignancies, Wei Liu, Hongying Feng, Paige A Taylor, Minglei Kang, Jiajian Shen, Jatinder Saini, Jun Zhou, Huan B Giap, Nathan Y Yu, Terence S Sio, Pranshu Mohindra, Joe Y Chang, Jeffrey D Bradley, Ying Xiao, Charles B Simone, Liyong Lin

Faculty, Staff and Student Publications

Stereotactic body radiation therapy (SBRT) and hypofractionation using pencil-beam scanning (PBS) proton therapy (PBSPT) is an attractive option for thoracic malignancies. Combining the advantages of target coverage conformity and critical organ sparing from both PBSPT and SBRT, this new delivery technique has great potential to improve the therapeutic ratio, particularly for tumors near critical organs. Safe and effective implementation of PBSPT SBRT/hypofractionation to treat thoracic malignancies is more challenging than the conventionally fractionated PBSPT because of concerns of amplified uncertainties at the larger dose per fraction. The NRG Oncology and Particle Therapy Cooperative Group Thoracic Subcommittee surveyed proton centers in …

Specific Patterns Of Endogenous Functional Connectivity Are Associated With Harm Avoidance In Obsessive-Compulsive Disorder, Merage Ghane, Lucas Trambaiolli, Michele A Bertocci, Freddyson J Martinez-Rivera, Henry W Chase, Tyler Brady, Alex Skeba, Simona Graur, Lisa Bonar, Satish Iyengar, Gregory J Quirk, Steven A Rasmussen, Suzanne N Haber, Mary L Phillips

Faculty, Staff and Student Publications

Background: Individuals with obsessive-compulsive disorder (OCD) show persistent avoidance behaviors, often in the absence of actual threat. Quality-of-life costs and heterogeneity support the need for novel brain-behavior intervention targets. Informed by mechanistic and anatomical studies of persistent avoidance in rodents and nonhuman primates, our goal was to test whether connections within a hypothesized persistent avoidance-related network predicted OCD-related harm avoidance (HA), a trait measure of persistent avoidance. We hypothesized that 1) HA, not an OCD diagnosis, would be associated with altered endogenous connectivity in at least one connection in the network; 2) HA-specific findings would be robust to comorbid symptoms; …

Variations Of Inflammatory Markers Levels (Esr And Crp) In The Perioperative Period Of Total Knee Arthroplasty, Khalil Ibrahim Sadiq, Mohamedbakir Abbas Abdulzahra, Rafid Mousa Jaffar

Iraqi National Journal of Medicine

Background: The preferred method of treatment for severe osteoarthritis of the knee is total knee arthroplasty (TKA). TKA has been linked to a significant increase in inflammatory markers such as erythrocyte sedimentation rate (ESR)—a test that measures how quickly red blood cells settle to the bottom of a test tube—and C-reactive protein (CRP)—a protein made by the liver that increases when there’s inflammation in the body. Aim: Assessment of the typical time trend and physiological kinetics of CRP and ESR during the early postoperative period over 4 weeks Methods: The study was conducted in the Basrah arthroplasty center, from June …

Comparative Analyses Of Immune Marker Levels In Seronegative And Seropositive Iraqi Rheumatoid Arthritis Patients, Ahmed Aledany, Eman Tariq Ali Altaee, Ali Nazar Mohammed, Falah Hassan Shari Alsukainy

Iraqi National Journal of Medicine

Background: Rheumatoid arthritis (RA) comprises an inflammation-based condition with a clinical phenotype that is mainly reliant on the occurrence of rheumatoid factor and anti-citrullinated protein antibodies. Literature indicates that seronegativity might be accompanied by higher severity of clinical symptoms, while higher disease activity, based on the recent classification criteria should also be associated with seronegativity. Aim: This investigation targets the identification of more efficient immune markers of RA seropositivity as well as examining the possibility that the latter is associated with lower severity. Methods: Serum samples from 128 RA patients, 106 seropositive and 22 seronegative, were analyzed using ELISA to …

Brain-Age Prediction: Systematic Evaluation Of Site Effects, And Sample Age Range And Size, Yuetong Yu, Hao-Qi Cui, Shalaila S Haas, Faye New, Nicole Sanford, Kevin Yu, Denghuang Zhan, Guoyuan Yang, Jia-Hong Gao, Dongtao Wei, Jiang Qiu, Nerisa Banaj, Dorret I Boomsma, Alan Breier, Henry Brodaty, Randy L Buckner, Jan K Buitelaar, Dara M Cannon, Xavier Caseras, Vincent P Clark, Patricia J Conrod, Fabrice Crivello, Eveline A Crone, Udo Dannlowski, Christopher G Davey, Lieuwe De Haan, Greig I De Zubicaray, Annabella Di Giorgio, Lukas Fisch, Simon E Fisher, Barbara Franke, David C Glahn, Dominik Grotegerd, Oliver Gruber, Raquel E Gur, Ruben C Gur, Tim Hahn, Ben J Harrison, Sean Hatton, Ian B Hickie, Hilleke E Hulshoff Pol, Alec J Jamieson, Terry L Jernigan, Jiyang Jiang, Andrew J Kalnin, Sim Kang, Nicole A Kochan, Anna Kraus, Jim Lagopoulos, Luisa Lazaro, Brenna C Mcdonald, Colm Mcdonald, Katie L Mcmahon, Benson Mwangi, Fabrizio Piras, Raul Rodriguez-Cruces, Jessica Royer, Perminder S Sachdev, Theodore D Satterthwaite, Andrew J Saykin, Gunter Schumann, Pierluigi Sevaggi, Jordan W Smoller, Jair C Soares, Gianfranco Spalletta, Christian K Tamnes, Julian N Trollor, Dennis Van't Ent, Daniela Vecchio, Henrik Walter, Yang Wang, Bernd Weber, Wei Wen, Lara M Wierenga, Steven C R Williams, Mon-Ju Wu, Giovana B Zunta-Soares, Boris Bernhardt, Paul Thompson, Sophia Frangou, Ruiyang Ge, Enigma‐Lifespan Working Group

Faculty, Staff and Student Publications

Structural neuroimaging data have been used to compute an estimate of the biological age of the brain (brain‐age) which has been associated with other biologically and behaviorally meaningful measures of brain development and aging. The ongoing research interest in brain‐age has highlighted the need for robust and publicly available brain‐age models pre‐trained on data from large samples of healthy individuals. To address this need we have previously released a developmental brain‐age model. Here we expand this work to develop, empirically validate, and disseminate a pre‐trained brain‐age model to cover most of the human lifespan. To achieve this, we selected the …