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An Ex Vivo Study Of Reuterin's Root Canal Irrigation Effect On Endodontic Biofilm Gene Expression, Armelia S. Widyarman, Muhammad I. Rizal, Thalianabilla Khalisha, Denisa N. Amanda, Deandra Cn. Wiriawan

Journal of Dentomaxillofacial Science

Objective: To assess the efficacy of irrigation solution containing reuterin in inhibiting gene expression of E. faecalis, F. nucleatum, and P. gingivalis during biofilm formation in ex vivo root canal model. Material and Methods: Reuterin was isolated from an Indonesian strain of L. reuteri. Seventy-two premolar root samples were subjected to inoculation with E. faecalis, F. nucleation, and P. gingivalis for 24 hours. Subsequently, the specimens underwent irrigation with a saline solution as negative control, 25% sodium hypochlorite (NaOCl) as positive control, 25 pg/ml of reuterin derived from a L. reuteri strain indigenous to Indonesia, and …

Developing Educational Tools For Sustainable Stormwater Management, Lauren Houskeeper

All Graduate Reports and Creative Projects, Fall 2023 to Present

Rapid population growth and development in Western states are exerting strain on the region’s limited water resources. Urbanization exacerbates this issue by increasing impervious surfaces, limiting infiltration of precipitation during storm events and snowmelt, which results in changes to hydrologic conditions with higher runoff volumes and higher peak flows. Stormwater transports pollutants as it flows across impervious surfaces, discharging high volumes of runoff and elevated loads of urban contaminants into receiving waters. The amount of pollution entering waterways continually increases as urban areas expand. Utah is currently experiencing a rapid transition from undeveloped to developed landscapes, necessitating the implementation of …

A Study Of Aquatic Sedimentation In Chattanooga, Tennessee, Using Gis And Remote Sensing Technology Integrated With Hydrodynamic And Watershed Models, Connor Firat

Masters Theses and Doctoral Dissertations

Suspended sediments can have benefits and drawbacks on aquatic ecosystems depending on the concentrations. The need to quantitatively monitor water bodies and watersheds is key to reduce excessive suspended concentrations. This study aims to integrate remote sensing technology with numerical watershed and hydrodynamic models and apply them on the Tennessee River and the surrounding tributaries to better assess the fate and transport of suspended sediment concentrations (SSC) there. The obtained results indicate that using Google Earth Engine (GEE), Landsat satellite can be used to estimate historical turbidity in the Tennessee River. Using field measurements and laboratory analyses the obtained satellite …

Topology And Geometry-Based Methods For Quantifying The Complexity Of Protein Structures, Masumi Sugiyama

Masters Theses and Doctoral Dissertations

New topological and geometrical methods in knot theory provide a way to rigorously measure the entanglement of open curves in 3-space for the first time. These methods enable the topological analysis of physical systems of filaments, such as those formed by proteins. In this dissertation we employ tools from knot theory in combination with available experimental data and molecular simulations to analyze the topological complexity of tau proteins. These proteins are involved in a class of neurodegenerative diseases, called tauopathies. The methods developed in this dissertation are general and applicable to other proteins as well as any physical systems of …

Predicting Hand Grasping Orientation For Prosthetic Hand Control Using Multimodal Sensor Data (Eeg, Emg, And Imu) With Machine Learning Approach, Nafiseh Ghaffar Nia

Masters Theses and Doctoral Dissertations

Enhancing the control of prosthetic hands is a crucial challenge that directly impacts the daily functionality of individuals with limb loss. Our research delves into advanced machine learning (ML) methodologies to accurately predict hand-grasping orientations, thereby improving the precision of prosthetic control. We present a comprehensive framework that amalgamates inputs from multiple sensors. This includes electroencephalography (EEG) to discern user intentions, electromyography (EMG) to evaluate muscle activity, and inertial measurement units (IMU) to track features of hand movement. By harmoniously integrating these varied data streams, our ML model strives to provide predictions of hand orientation that are more accurate and …

High Fat Diet & Social Isolation: Interactive Effects On Pain, Cognition, & Neuroinflammation, Ian M. Campuzano

Research Psychology Theses

Prior research has established a role for both social isolation and exposure to high fat Western diets in altering a range of behaviors from reduced memory performance to increased depression-like behaviors. The present study scrutinizes the interplay among these variables during the peri-adolescent developmental phase, utilizing Long-Evans rats as the experimental model. Our overarching hypothesis is that rats exposed to either social isolation, a high-fat diet, or both will result in heightened pain sensitivity, diminished cognitive flexibility, and increased neuroinflammatory responses within brain regions implicated in sociability, cognition, memory, and pain processing. Behavioral flexibility will be assessed using a maze-based …

Factors Impacting Treatment Decisions In Caregivers Of Autistic Children, Tiffany Harris

Dissertations

Caregivers of autistic children are not only tasked with deciding upon various treatment options for their children’s symptoms but must also navigate the initial crisis that is experienced after receiving a diagnosis of ASD for their children (Blancher, 1984; Ellis, 1989). Leventhal’s Common Sense Model of Self-Regulation (the CSM; Leventhal et al., 1980) is a theoretical framework developed to understand the self-regulatory processes involved in adapting to and managing health threats and posits that cognitive and emotional illness perceptions influence illness outcomes through coping behaviors. This is the first study to examine all major components of the CSM (i.e., cognitive …

Examining The Association Between Parental Attachment, Fictive Kin Bonds, Psychological Needs Satisfaction, Emotional Distress, And Subjective Well-Being Among Black Americans, Roxanne Watts

Dissertations

Secure attachment with parents predicts less emotional distress and greater subjective well-being across the lifespan. One mechanism by which parental attachment supports mental health outcomes is through psychological needs satisfaction (PNS). In addition to the attachment to parents, relationships with fictive kin caregivers are prevalent and important among Black families. The present study investigated the association between parental attachment, fictive kin bonds, psychological needs satisfaction and mental health outcomes (i.e., emotional distress and subjective well-being) in a sample of Black American adults. Two hundred twenty-three (N = 223) participants completed measures of parental attachment, fictive-kin bonds, psychological needs satisfaction …

Understanding The Relations Between Parental Psychological Distress And Child Emotional And Behavioral Problems: A Path Analysis, Lauren S. Erp

Dissertations

Maternal psychological distress has consistently been linked to emotional and behavioral problems in school-aged children. Given the high prevalence and negative outcomes of child emotional and behavioral problems, parenting variables have been examined as mechanisms underlying this relation. Research has demonstrated that mothers who endorse high psychological distress report high parenting stress, which contributes to the use of more negative parenting practices. Moreover, parenting stress has been shown to relate to negative parenting practices through parenting inflexibility. Yet, no known study has examined parenting stress, negative parenting practices, and parenting inflexibility as pathways through which parental psychological distress relates to …

Adverse Childhood Experiences And Career Decision Making In College Students: Investigating The Moderating Effects Of Perceived Covid-19 Impact And Ambiguity Tolerance, Kendall Klumpp

Dissertations

College students face many difficult decisions as they navigate adulthood, including making a decision about their career. Although much research has already been conducted to explore these difficulties, little has explored the potential impact of adverse childhood experiences (ACEs) on one’s career-related cognitions. Further, the COVID-19 pandemic has provided a new context in which difficulties with career-related decisions may be exacerbated. Through the lens of psychological stress, the current study examined the responses of 231 undergraduate students using a university-based online participant recruiting site, SONA. It was predicted that level of ACEs would be positively related with levels of negative …

Patterns Of The Use And Perception Of Cannabis Among College Students In Tennessee, Jayla Ruffus-Milner

Electronic Theses and Dissertations

Cannabis has been historically difficult to research due to its federal scheduling. However, as legalization of cannabis medically, recreationally, or both in states across the country has increased, so has the need to address the research gaps that persist. The purpose of this study was to explore the patterns of cannabis use and perceptions of college students in Tennessee, which encompass a demographic of mainly young adults who are typically associated with high usage patterns. The study uses quantitative data collected from an online survey sent to a university in East Tennessee to evaluate associations between students’ age, gender, race/ethnicity, …

University Of Central Florida Undergraduate Catalog, 2024 - 2025, University Of Central Florida

UCF Catalogs

No abstract provided.

An Analysis Of Fish Assemblages And Flow Regimes Upstream And Downstream Of Falcon Reservoir, Christopher J. Austin

Theses and Dissertations

The lower Rio Grande is regulated by Falcon and Amistad dams. Native fish species rely on the natural flow regime for habitat and spawning. I analyzed streamflow discharge and fish assemblages above and below Falcon Reservoir to assess potential impacts of dam impoundment. Fish collections were conducted by seine, and river discharge data was provided by the International Boundaries and Water Commission. I found significant differences in fish assemblages above vs below Falcon Reservoir, and the flow regime was significantly more altered downstream of Falcon Reservoir. I also identified two Species of Greatest Concern for Texas above Falcon Reservoir (Notropis …

Documenting The Spatial And Temporal Dynamics Of Pair-Rule Genes In The Early Tribolium Embryo, Hasan Mahmud

Theses and Dissertations

Although Insects and vertebrates have different anatomical structures, they possess similar mechanisms for segmenting during embryogenesis. Clock and wavefront model exhibit a similar pattern of division as observed in Drosophila, like vertebrates, which emphasizes fundamental principles in the field of developmental biology. In contrast to Drosophila, the insect Tribolium castaneum exhibits posterior segmentation originating from the growth zone. The pair-rule genes’ expression is characterized by oscillatory patterns, which are controlled by a segmentation clock. Researchers found that the speed regulation model combines oscillatory and sequential gene activities to shape both elongating and non-elongating embryonic tissues. The adaptability of this model …

Synthesis And Characterization Of Medicinally Privileged Aza Heterocycles, Nneoma James

Theses and Dissertations

Four-membered cyclic amides, commonly known as β-lactams, have played a crucial role in drug discovery research since its discovery by Alexander Fleming in 1928 from Penicillium notatum. The β-lactam antibiotics are broadly effective against several bacterial infections through acylating the transpeptidase involved in cross-linking peptides to form peptidoglycan or periplasmic murein, which is a fundamental constituent of the bacterial cell wall for both the gram-positive (ten or more layers) and gram-negative (one or two layers) bacteria. Although for more than eight decades, β-lactams have been recognized as antibiotics, later, other medicinal activities of β-lactam derivatives have been reported, including lowering …

Chemical Investigation Of The Ethanol Extract Of Tillandsia Usneoides (Spanish Moss), Jakir Hossain

Theses and Dissertations

Tillandsia usneoides in epiphytic bromeliads takes up water through absorptive trichomes on the shoot surface under extreme environmental conditions. Although previous studies revealed the way by which T. usneoides absorbs water and prevents water loss, its water transport remains unclear. Uses of T. usneoides L. have been documented going back to pre-Columbian and late archaic societies. Between the 1800s and 1900s. T. usneoides was utilized in fruit packing and polish, among other industrial goods. In terms of medicine, tillandsia is well-known for treating leucorrhea, rheumatism, ulcers, hemorrhoids, and as an anti-diabetic, emetic, analgesic, purgative, antispasmodic, and diuretic. The chemical composition …

Label-Free Laser-Induced Graphene-Based Electrochemical Biosensor Modified With Graphene-Conductive Polymer Ink Coating For Detection Of Alpha-Fetoprotein And 17Β – Estradiol, Ridma Tabassum

Theses and Dissertations

In this study, a novel electrochemical biosensor was proposed based on inducing graphene formation on polyimide substrate via laser engraving. Graphene polyaniline (G-PANI) conductive ink was synthesized by planetary mixing and applied to the working zone of the developed sensor to effectively enhance the electrical signals. The laser-induced graphene (LIG) sensor was used to detect alpha-fetoprotein (AFP) and 17β-Estradiol in the phosphate buffer saline (PBS) buffer and human serum. The electrochemical performance of the biosensor in determining these biomarkers was investigated by differential pulse voltammetry (DPV) and chronoamperometry (CA). In a buffer environment, alpha-fetoprotein (AFP) and 17β-Estradiol detection range were …

Unveiling Eureka Math: A Critical Peek Behind The Curricular Curtain, Jennifer L. Goldin-Weeks

Theses and Dissertations

While contemporary mathematics education literature argues that curricular resources, such as textbooks, play a significant role guiding mathematics teachers in what and how they teach, it also shows that these resources often do not do what they say they will do, nor adhere to the standards they claim to further. When it comes to the most utilized mathematics curricular resource in the United States, Eureka Math, there is a lack of scholarly literature investigating these types of claims made by the publisher. This study aimed to explore how the Eureka Math curricular resources are positioned within the context of the …

Validation, Optimization, And Experimentation Of Electro-Centrifugal Spinning, Carlos Alberto Delgado

Theses and Dissertations

The aim of this study is to understand the behavior of polymeric solutions, when exposed to both electric fields and centrifugal forces through the electro-centrifugal fiber creation method, observing both effects of various parameter variations on the resulting nanofibers. The elemental deposition on electrospun fibers through in-situ processes is studied and optimized. The morphology, crystallinity, thermal properties, and elemental composition of the nanofibers were characterized. The purpose of these nanofibers is for future applications such as energy harvesting, filtration, and biomedical applications.

Advancements In Aerial Vehicle Platforms: A Guide For Design, Validation, And Implementation Of 3d Printed Drones, Alan Salvador Urteaga

Theses and Dissertations

Additive manufacturing methods have revolutionized the way products are designed and developed through a product's entire design life cycle. This is in part correlated with the nature of additive manufacturing methods that differentiate them from traditional methods. Some of the benefits of additive manufacturing methods include customizability, rapid prototyping, the production of complex design geometry, and embedded assembly manufacturing. Unmanned aerial vehicles have been on the rise for various military, commercial, or personal applications. The focus of this study is to provide detailed instructions on how to engineer a viable drone design that is impact-resistant, modular, and customizable. This study …

Synthesis Of Silicon Carbide, Titanium Nitride, And Titanium Carbide Nanofibers: Exploring Novel Approaches With Unique Precursors, Jahaziel Eduardo Cavazos

Theses and Dissertations

Ceramics such as β-silicon carbide (β-SiC), titanium nitride (TiN), and titanium carbide (TiC) are profoundly studied in high-temperature and harsh environments given the properties each ceramic exhibit, including high mechanical strength and toughness, excellent thermal shock resistance, and chemical inertness. The development of nanofibers has evolved from electrospinning to Forcespinning®—the latest proving potential for high yield production in industrial applications. This thesis presents the work conducted on the synthesis-structure-property relationships of TiN and TiC nanofiber systems. The nanofibers were synthesized utilizing Ti precursors and subjecting the solutions to the Forcespinning® method. Developed nanofiber systems were subjected to post processing heat …

Development Of The Structure And Control System Of A Stewart Platform Robot For Human Balance Recovery Interventions, Rhobenn R. Alvarez Zambrano

Theses and Dissertations

In this thesis, the process to design a Stewart platform parallel robot for balance recovery with given assembly constraints and mobility requirements is described. A Model Based Design (MBD) approach in MATLAB was used as a tool to model and optimize the design of the platform through quick and repeatable workspace and movements simulations. An algorithm based on Inverse Kinematics was used to find the most adequate Stewart platform configuration which yields a workspace that fulfills the design goals best. Solidworks was used as a 3D CAD Modeling tool to elaborate machining blueprints while ensuring that each piece fits accurately …

Application Of Functionalized Organosilicas In Adsorption Of Nitrates, Stephen Amoako

Electronic Theses and Dissertations

This study addresses the critical environmental issue of elevated nitrate levels in water bodies, primarily due to excessive use of nitrogenous fertilizers and improper waste disposal. It focuses on reducing nitrate concentrations in polluted water to permissible levels through the effectiveness of hybrid materials in nitrate adsorption. We synthesized nine amino-functionalized adsorbents using grafting and sol-gel techniques. Batch adsorption tests confirmed the high nitrate adsorption capacities of these adsorbents, with sol-gel materials showing the highest efficiency due to their abundant amino group contents. Among these, the surfactant-free, sol-gel adsorbent was the most effective, combining ease of synthesis with cost-efficiency. Our …

Exploring The Diagnostic Potential Of Radiomics-Based Pet Image Analysis For T-Stage Tumor Diagnosis, Victor Aderanti

Electronic Theses and Dissertations

Cancer is a leading cause of death globally, and early detection is crucial for better

outcomes. This research aims to improve Region Of Interest (ROI) segmentation

and feature extraction in medical image analysis using Radiomics techniques

with 3D Slicer, Pyradiomics, and Python. Dimension reduction methods, including

PCA, K-means, t-SNE, ISOMAP, and Hierarchical Clustering, were applied to highdimensional features to enhance interpretability and efficiency. The study assessed the ability of the reduced feature set to predict T-staging, an essential component of the TNM system for cancer diagnosis. Multinomial logistic regression models were developed and evaluated using MSE, AIC, BIC, and Deviance …

The Effects Of Grading Equity Practices On Students: Do Student Perceptions Of And Teachers’ Exposure To Grading Equity Practices Matter?, Sarah Ruth Morris

Graduate Theses and Dissertations

This dissertation critically examines grading practices within schools, tracing the evolution from traditional to modern approaches and highlighting the social dimensions and debates surrounding grading. Through a mixed-methods study spanning three empirical chapters, it explores students' and teachers' perceptions of grading practices, the impact of professional development (PD) on teachers' approaches to grading equity, and the resultant effects on student outcomes. Chapter Two reveals students' preferences for practices that recognize effort and support academic growth, alongside a tension between Pre-AP students' resistance and the support from students under high stress. Chapter Three finds that while PD can shift teachers' views …

Distribution Dynamics Of Swamp Rabbits (Sylvilagus Aquaticus) In Missouri, Kylie Bosch

Theses

Swamp rabbits (Sylvilagus aquaticus) are a bottomland hardwood forest specialist undergoing contraction at the northern extent of their range. This decline is often attributed to the loss of bottomland hardwood forest and frequent, intense flooding. To mitigate this decline and inform decisions regarding the swamp rabbit’s conservation status, there is a pressing need for long-term monitoring efforts. Although currently listed as imperiled (S2) in Missouri, shifts in occupancy trends may warrant a reassessment of the swamp rabbit’s state rank. The Missouri Department of Conservation has conducted decadal surveys for swamp rabbits since 1991, and the work presented here describes the …

Ecological Drivers Of Size And Predictors Of Potential Competition In Soricidae, Wesley B. Holland

Theses

The family Soricidae, encompassing shrews, represents a diverse group of small (head-body length 30-178 mm) omnivorous or carnivorous mammals distinguished by unique morphological and physiological traits. Ecologically, shrews are dominant small predators, significantly impacting invertebrate populations. Their foraging strategies are diverse, with species adapted to fossorial, psammophilic, scansorial, semiaquatic, semifossorial, and terrestrial guilds. High metabolic rates necessitate nearly constant food intake, influencing their prey selection and feeding behaviors. Physiologically, shrews exhibit adaptations for thermoregulation, with Soricinae generally having higher mass-specific metabolic rates compared to Crocidurinae, who can enter torpor to conserve energy. These metabolic differences are crucial for their ecological …

An Exploration Of Factors Driving Patterns Of Hybridization In Triodanis, Keegan Sean Mcconnell

Theses

Elucidating and preserving biodiversity is an essential component of biological research, yet many natural processes impede our ability to define basic patterns of biodiversity. Hybridization is a common process in flowering plants, with a range of outcomes that influence our understanding of species ecology and evolution. In many systems, factors that facilitate or prevent successful hybridization are poorly understood. In this study, I investigate various potential mechanisms driving patterns of hybridization between Triodanis biflora and T. perfoliata. Previous research in this system has documented extensive hybridization, but some work has also alluded to the potential role of the breeding system …

The Expression Of Genes Tlr2 And Tlr10 In The Gastric Tissue Of Patients With Gastroduodenal Disorders Caused By Helicobacter Pylori, Samara Kadhim Mohammed, Marrib N. Rasheed, Basim Ahmed ِAsker

Baghdad Science Journal

The bacterium Helicobacter pylori (H. pylori) is the key etiological agent in gastritis, peptic ulcer, and gastric cancer disease. Toll-like receptors (TLRs) contribute to the innate immune response through pathogen-associated molecular patterns (PAMPs) derived from H. pylori and other microorganisms as well as damage-associated molecular patterns (DAMPs) derived from host cells, such as tumour cells, dead or dying cells, or products released from cells in response to signals such as hypoxia. The study involved gastric biopsies taken from 88 gastroduodenal disorder patients and 21 healthy individuals. The clinical diagnoses of these groups after endoscopy examination included gastritis, peptic ulcers, and …

Evaluation Of The Potential Protective Role Of Galangin Associated With Gold Nanoparticles In The Histological And Functional Structure Of Testes Of Adult Male Albino Mice Administrated With Carbon Tetrachloride, Bassem Sultan Abeed, Hanady Salim Al-Shmgani

Baghdad Science Journal

Galangin (Gal) is a natural flavonoid sourced from the roots of the plant Albina Kalanga. It possesses a variety of pharmacological activities, such as antioxidant, anticancer, and anti-inflammatory. The current study aims to enhance the efficacy of galangin through the use of gold nanoparticles as a drug delivery system against CCl4-induced toxicity in the testicular tissue of male albino mice. Forty-two albino mice were divided into seven groups (6 mice/group), treatment with carbon tetrachloride solution for two weeks by intraperitoneal injection, (1 ml/kg) once a week for all groups except the control group, after which a group was injected with …