Digital Commons Network^™

Advancing Drug Discovery And Disease Understanding Through Knowledge Graphs And Machine Learning Techniques, Swastika Tenkila Purushotham

Electrical and Computer Engineering ETDs

This thesis investigates knowledge graphs with particular reference to the NIH-funded Common Fund Data Ecosystem Data Distillery project. By combining data from nine Common Fund projects and other sources, this project has created a large knowledge graph using Neo4j. To find new and undiscovered drug targets, UNM’s Illuminating the Druggable Genome (IDG) Data Coordinating Center has supplied data and use cases. Condensed Knowledge Graph, a condensed version that is based on the Data Distillery Knowledge Graph, improves usability for IDG applications. Condensed Knowledge Graph research endeavors to enhance data organization through the categorization of disease terms, examination of Cerebellar Stroke …

November 5, 2024 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

The Personality Profile And Leadership Style Of U.S. Vice President And 2024 Democratic Presidential Nominee Kamala Harris, Aubrey Immelman, Anne Marie Griebie, Elise Vomacka

Psychology Faculty Publications

The paper presents the results of an indirect personality assessment of U.S. vice president Kamala Harris, Democratic presidential nominee in the 2024 U.S. presidential election, from the conceptual perspective of personologist Theodore Millon.

Psychodiagnostically relevant data about Harris were collected from biographical sources and media reports and synthesized into a personality profile using the Millon Inventory of Diagnostic Criteria (MIDC), which yields 34 normal and maladaptive personality classifications congruent with DSM-III-R, DSM-IV, and DSM-5-TR.

The personality profile yielded by the MIDC was analyzed in accordance with interpretive guidelines provided in the MIDC and Millon Index of Personality …

November 2024 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.

Environmental Drivers Of The Divergence Of Harveyi Clade Pathogens With Distinctive Virulence Gene Profiles, Andrei L. Barkovskii, Cameron Brown

Faculty and Staff Works

Fish and shellfish pathogens of the Harveyi clade of the Vibrio genus cause significant losses to aquaculture yields and profits, with some of them also causing infections in humans. The present study aimed to evaluate the presence of Harveyi clade fish and shellfish pathogens and their possible diversification in response to environmental drivers in southeastern USA waters. The presence and abundance of potential pathogens were evaluated via the detection and quantitation of six Harveyi-clade-specific virulence genes (toxR, luxR, srp, vhh, vhh, and vhp; VGs) in environmental DNA with clade-specific primers. The environmental DNA was obtained from water and sediments collected …

Characterizing The Temporal And Nearshore To Offshore Spatial Scale Of Phytoplankton Assemblages Within The Florida Keys National Marine Sanctuary, Sebastian P. Di Geronimo

USF Tampa Graduate Theses and Dissertations

This study investigates the spatial and temporal dynamics of phytoplankton communities within the Florida Keys National Marine Sanctuary (FKNMS) from 2016 to 2021. Phytoplankton biomass and community composition were analyzed across four seasons and from both Nearshore (within 2 km of shore) and Offshore (8 to 10 km from shore) locations along the Florida Keys from Miami to the Western Sambo Ecological Reserve. High-performance liquid chromatography (HPLC) quantified chlorophyll-a (tchla) as a proxy for bulk biomass, and other pigments. CHEMTAX, a chemotaxonomic identification method, was employed to estimate phytoplankton community composition. Our results revealed significant seasonal variability in bulk biomass, …

Ucc Minutes 11-5-24, Angela Brock

UCC Agendas/Minutes

No abstract provided.

The Role Of Sociability In Mental Health In Mid To Late Life During Covid-19, Katherine L. Fiori, Amy Rauer, Christina M. Marini, Amna Khan, Christine So

Journal of Social, Behavioral, and Health Sciences

Some adults in mid and late life may have been particularly sensitive to the negative effects of social disruptions due to COVID-19 restrictions. The current study explored whether sociability moderated links between disrupted contact with friends and family and multiple indicators of mental health. We collected quantitative data via an online survey from a community sample of 136 adults in mid to late life (M age = 67.77, range 50–91; 69.3% females; 92.7% White). We conducted a series of hierarchical linear regressions to test for moderation. Controlling for age, gender, and marital status, sociability moderated the associations between disruptions …

Kratom: A Narrative Review Of The Possible Clinical Uses And Dangers Of This Opioid-Like Plant, Amber N. Edinoff, Sarah E. Kaufman, Taylor C. Mahoney, William C. Upshaw, Jay Gong, Elyse M. Cornett, Kevin S. Murnane, Adam M. Kaye, Giustino Varrassi, Sahar Shekoohi, Alan D. Kaye

School of Medicine Faculty Publications

The term "kratom" refers to a plant species formally known as Mitragyna speciosa. Kratom is composed of over 40 alkaloids, a type of organic compound that contains nitrogen. These compounds work primarily via binding to opioid receptors expressed on neurons, where they stimulate signal transduction mechanisms involving the activation of G proteins. Kratom has been shown to cause both a stimulant-like effect and a sedative effect in humans. These studies have shown that use is highest among European-American, middle-class men living in suburban areas. Additionally, individuals who have a history of opioid misuse are also more likely to take kratom. …

Diversity And Evenness Of Birds During Seasonal Paddy Farming Practice In Southwestern Sarawak, Ivana Berlinda Bilang, Mohamad Fizl Sidq Ramji, Siti Nurlydia Sazali, Andrew Alek Tuen, Wan Nurainie Wan Ismail

Turkish Journal of Zoology

The influence of seasonal paddy farming activities on the paddy field environment and its composition of birds could be visually observed but has yet to be systematically studied and is still relatively understudied in Malaysian Borneo. Earlier research relied solely on point counts and not using line transects or mist nets for data collection could have resulted in missing and biased findings. Thus, this study aims to evaluate and compare species diversity and evenness of birds in different paddy stages in southwestern Sarawak with previous studies conducted in the region. We reported a higher species richness than previous reports from …

Community-Led Workshops To Engage Action For Food System Change (Foodsequal), Clare Pettinger, Louise Hunt, Hannah Gardiner, Lisa Howard, Carol Wagstaff

School of Health Professions

Background: The UK food system is distorted by inequalities of access for socially and economically disadvantaged communities. There is a need for novel approaches whereby communities can lead food system change. Research Objective: This study aimed to explore creative methods (delivered by community members) to support dietary benchmarking activities as part of a UK consortium food system transformation research project (FoodSEqual, 2021). Methods: Several ‘shopping basket’ workshops were run to ‘sense check’ national dietary datasets against local community lived experience, seeking aspirational views on dietary change. Informed by UK data synthesis (Methven et al 2022), workshops were co-designed by community …

Engaging Secondary Schools In Food Activities – Curriculum Enrichment (Foodsequal), Clare Pettinger

School of Health Professions

Background: Secondary schools in disadvantaged communities are vulnerable to poor food provision. Food literacy in children builds skills and confidence to support lifelong healthy (sustainable) eating habits (Carroll et al 2021). Research Objective: The aim of this study was to co-design a food-themed curriculum enrichment week for secondary school children to explore food literacy and school food culture (FoodSEqual, 2021) Methods: A series of taster sessions (cooking; filming; games; discussions) were run to introduce ideas. This informed co-design of food-themed curriculum enrichment week activities. Food literacy focus groups were run with students; interviews with school teachers (school food culture); observations …

Failure To Rescue Black And Brown Maternity Patients, Dorothy Marie Glisson

Walden Dissertations and Doctoral Studies

Reducing maternal mortality rates is one of the leading health indicators in the nation. Pregnant and postpartum Black mothers make up a disproportionate number of maternal deaths. Many result from failure to rescue (FTR), defined as the inability to prevent a death from a disease, illness, or complication. Over 700 women die daily from preventable causes related to pregnancy. Black patients are attributable to almost 40% of maternity mortality rates and represent over 50% of pregnancy-related deaths due to complications. Black women are more likely to die during pregnancy or after pregnancy, with heart disease causing almost half of pregnancy-related …

Counselors’ Experience With Male Opioid Abuse Clients With Anxiety And Depression During The Covid-19 Pandemic, Sheila J. Stauffer

Walden Dissertations and Doctoral Studies

There has been a spike in overdoses in the United States resulting in approximately 100,306 deaths since the COVID-19 pandemic began with overdose results from men in opioid and fentanyl abuse with a shortage of resources for substance use disorders and mental health. Families across the U.S. have been affected with the social problem of substance abuse disorders for many years due to environmental and biological constructs due to loss of jobs, housing, limited childcare, and exposure to drugs and alcohol at an early age. The present phenomenology qualitative study explored counselors’ experience working with male clients who abuse opioids …

Failure To Rescue Black And Brown Maternity Patients, Dorothy Marie Glisson

Walden Dissertations and Doctoral Studies

Reducing maternal mortality rates is one of the leading health indicators in the nation. Pregnant and postpartum Black mothers make up a disproportionate number of maternal deaths. Many result from failure to rescue (FTR), defined as the inability to prevent a death from a disease, illness, or complication. Over 700 women die daily from preventable causes related to pregnancy. Black patients are attributable to almost 40% of maternity mortality rates and represent over 50% of pregnancy-related deaths due to complications. Black women are more likely to die during pregnancy or after pregnancy, with heart disease causing almost half of pregnancy-related …

Satellite-Based Mapping Of Seagrass Habitats And Coastal Wetlands In The Us Gulf Of Mexico And Florida: A Remote Sensing Approach For Environmental Conservation And Management, Luis Lizcano-Sandoval

USF Tampa Graduate Theses and Dissertations

Coastal wetlands and seagrass meadows provide multiple services to nature and human society, but their spatial and temporal changes are often not well characterized. They are habitats that are threatened by natural and human causes such as changes in water quality, urban development, pollution, and climate change, among others. Coastal ecosystems rely on water quality and sea level variability for survival, and changes in those variables and their potential effects are of concern to many coastal communities. Satellite remote sensing is a powerful tool that has been used for mapping ecosystem distribution on land and in the ocean. Satellite sensors …

Targeting Tumor Microenvironmental Factors In Bladder Cancer To Enhance Responses With Immunotherapy, Sarah Bazargan

USF Tampa Graduate Theses and Dissertations

Bladder cancer is the tenth most common cancer in the world and has one of the highest recurrence rates. Despite the local delivery options and mutational status of bladder tumors, responses with immunotherapies have been limited with low durability. The bladder tumor microenvironment is enriched with highly immunosuppressive populations and harsh conditions that restrict anti-tumor immunity and subsequently attenuate immunotherapy response. We predict that targeting two of these immunosuppressive components, namely acidity and myeloid derived suppressor cells (MDSCs), will bolster T cell responses and enhance outcomes with immunotherapy. In Chapter 2, we characterized the effects of acidity on T cell …

Understanding The Welfare Of Aquarium Fish, Paul Rose

Animal Sentience

Bony fishes (Osteichthyes) are prevalent in public and domestic aquaria, yet evidence-based welfare practices exist for only a limited number of species. Oldfield & Bonano’s (O&B’s) target article highlights critical questions about the wellbeing and sociality of Osteichthyes. Advancing research on their biology, physiology, psychology, and behavior is essential to develop and validate welfare measures, ensuring guidelines for welfare-focused housing and husbandry.

Counselors’ Experience With Male Opioid Abuse Clients With Anxiety And Depression During The Covid-19 Pandemic, Sheila J. Stauffer

Walden Dissertations and Doctoral Studies

There has been a spike in overdoses in the United States resulting in approximately 100,306 deaths since the COVID-19 pandemic began with overdose results from men in opioid and fentanyl abuse with a shortage of resources for substance use disorders and mental health. Families across the U.S. have been affected with the social problem of substance abuse disorders for many years due to environmental and biological constructs due to loss of jobs, housing, limited childcare, and exposure to drugs and alcohol at an early age. The present phenomenology qualitative study explored counselors’ experience working with male clients who abuse opioids …

Counselors’ Experience With Male Opioid Abuse Clients With Anxiety And Depression During The Covid-19 Pandemic, Sheila J. Stauffer

Walden Dissertations and Doctoral Studies

There has been a spike in overdoses in the United States resulting in approximately 100,306 deaths since the COVID-19 pandemic began with overdose results from men in opioid and fentanyl abuse with a shortage of resources for substance use disorders and mental health. Families across the U.S. have been affected with the social problem of substance abuse disorders for many years due to environmental and biological constructs due to loss of jobs, housing, limited childcare, and exposure to drugs and alcohol at an early age. The present phenomenology qualitative study explored counselors’ experience working with male clients who abuse opioids …

Failure To Rescue Black And Brown Maternity Patients, Dorothy Marie Glisson

Walden Dissertations and Doctoral Studies

Reducing maternal mortality rates is one of the leading health indicators in the nation. Pregnant and postpartum Black mothers make up a disproportionate number of maternal deaths. Many result from failure to rescue (FTR), defined as the inability to prevent a death from a disease, illness, or complication. Over 700 women die daily from preventable causes related to pregnancy. Black patients are attributable to almost 40% of maternity mortality rates and represent over 50% of pregnancy-related deaths due to complications. Black women are more likely to die during pregnancy or after pregnancy, with heart disease causing almost half of pregnancy-related …

Nkp46+ Ilc3s Promote Early Neutrophil Defense Against Clostridioides Difficile Infection Through Gm-Csf Secretion, José L Fachi, Sarah De Oliveira, Susan Gilfillan, Alina Ulezko Antonova, Jinchao Hou, Marco A R Vinolo, Marco Colonna

2020-Current year OA Pubs

No abstract provided.

Cover And Contents

Turkish Journal of Zoology

No abstract provided.

An Important Species For Black Sea Biodiversity: Some Population Characteristics Ofinvasive Sea Vase (Ciona Intestinalis Linnaeus, 1767) Distributed On The Sinop Shores, Zeki̇ye Bi̇ri̇nci̇ Özdemir, Eylem Aydemi̇r Çi̇l, Süleyman Özdemi̇r, Hünkar Avni̇ Duyar

Turkish Journal of Zoology

This study aims to provide a comprehensive summary of the fundamental biological and certain population characteristics of Ciona intestinalis found along the Black Sea coasts of Turkey. The research was conducted between September 2022 and April 15, 2023, off the Sinop coast of the Black Sea, utilizing samples collected by commercial fishing vessels in the region. A total of 103 specimens of Ciona intestinalis were examined during the study. The average total length, width, and weight of Ciona intestinalis were determined to be 3.614 ± 0.089 cm, 1.967 ± 0.054 cm, and 2.004 ± 0.067 g, respectively. The length-weight relationship …

A New Pycnogonid Species From Türkiye: Anoplodactylus Gullukensis N. Sp. (Pycnogonida, Phoxichilidiidae), With An Identification Key To The Turkish Species Of The Genus, Cengi̇z Koçak

Turkish Journal of Zoology

A new species of pycnogonid collected from the shallow waters in Güllük Bay (Aegean Sea), Anoplodactylus gullukensis n. sp., is described and illustrated. Description of taxonomic characters of this species are given and differences from related species are indicated. An identification key for Anoplodactylus species known from Türkiye is provided.

On The Occurrence Of Two Lessepsian Fishes In The Southern Tyrrhenian Sea: Filefish Stephanolepis Diaspros And Goatfish Upeneus Pori, Carlo Pipitone, Fabio Badalamenti, Giovanni D'Anna, Giuseppe Di Stefano, Arturo Zenone

Turkish Journal of Zoology

The reticulated leatherjacket Stephanolepis diaspros and the Por’s goatfish Upeneus pori occur as lessepsian migrants in the eastern and central Mediterranean Sea. This article reports about the findings of one reticulated leatherjacket and two Por’s goatfishes in the Gulf of Castellammare, southern Tyrrhenian Sea, which suggest a possible westbound expansion of the Mediterranean distribution for the latter species. The specimens were three adults collected by professional fishermen on inshore sandy bottoms with a trammel net. The main meristic characters of both species, the identification issues in S. diaspros and the potential impact of U. pori on the native biota and …

Determination Of Spermatogenesis Activity Using Lectin Histochemistry In Water Monitorlizards (Varanus Salvator) Harvested From The Wild, Andhika Yudha Prawira, Ni Luh Putu Rischa Phadmacanty, Gono Semiadi, Hellen Kurniati, Wahyu Trilaksono, Nurhidayat Nurhidayat, Savitri Novelina

Turkish Journal of Zoology

Lectin is often used to investigate the differentiation and maturation of spermatogenic cells in the testes of several wild animals, facilitating the screening of mature individuals. Therefore, this study aimed to determine spermatogenesis activity using lectin histochemistry in water monitor lizards harvested from the wild. Testes of 43 comprehensively examined water monitor lizards (Varanus salvator) were collected from slaughterhouses in Palembang (Sumatra) and Banten (West Java), Indonesia, with Snout-Vent Length (SVL) ranging from 39 to 96 cm. Additionally, histologic, histomorphometric, Periodic Acid-Schiff (PAS) staining, and lectin histochemistry (Con A, RCA, WGA, PNA, VVA, DBA, UAE-I) observations were performed. The results …

Length-Weight Relationships And Condition Factor Of 30 Species From The Upper Syr Darya Drainage, Uzbekistan, Obboskhon Azamov, Sharofiddin Khalimov, Sultonbek Gulomov, Dildorakhon Komilova, Yorkinoy Kayumova, Murodjon Rakhmonov, Shahnoza Abdulatipova, Ominakhon Gafurova, Kholidakhon Komilova, Mushtariy Asrolova, Dilafruz Urmonova, Bakhtiyor Sheraliev

Turkish Journal of Zoology

Length-weight relationships (LWR) were estimated for 30 fish species i.e. Abbottina rivularis, Alburnus chalcoides, A. oblongus, A. taeniatus, Carassius gibelio, Channa argus, Cottus spinulosus, Cyprinus carpio, Gambusia holbrooki, Glyptosternon oschanini, Gobio lepidolaemus, Hemiculter leucisculus, Hypophthalmichthys nobilis, Iskandaria kuschakewitschi, Luciobarbus conocephalus, Micropercops cinctus, Opsariichthys bidens, Pelecus cultratus, Petroleuciscus squaliusculus, Pseudorasbora parva, Rhinogobius cf. lindbergi, Rhodeus ocellatus, Sabanejewia aralensis, Salmo oxianus, Schizothorax eurystomus, Triplophysa daryoae, T. elegans, T. ferganaensis, T. labiata, and T. strauchii from the Upper Syr Darya drainage, Uzbekistan. The LWR parameters were determined using a linear logarithmic regression model of weight against length in which values for the slope …

Not Just Any Tree: The Influence Of Leaf Characteristics On The Nest Site Selection Ofasian Weaver Ants, Amira Aqilah Muhammad, Noorhidayah Mamat, Kien-Thai Yong, Nurul Ashikin Abdullah

Turkish Journal of Zoology

The connection between plant species and nest site preference for the Asian weaver ant Oecophylla smaragdina remainspoorly understood despite their common occurrence in the urban areas of tropical regions. We predicted that plant species with specificleaf characteristics influence the nesting preference of Asian weaver ants, given that plant foliage is the main component of their neststructure. We studied the leaf characteristics of the tree species in which their nests were detected, including leaf shape, leaf apex shape,and leaf arrangement. Of the 206 total trees among the 20 tree species sampled, 185 trees from 18 tree species had at least one …

Gene Discovery From Microbial Gene Libraries I: Protection Against Reactive Oxygen Species-Driven Dna Damage, John C Taylor, Carmen Gu Liu, James D Chang, Brianna E Thompson, Anthony W Maresso

Faculty, Staff and Students Publications

Reactive oxygen species (ROS) pose a lethal risk for all life forms by causing damage to cell processes, genome-wide DNA damage-driving mutation, replicative instability, and death. Thus, the development of mechanisms to resist or repair ROS-induced DNA damage is critical for the reliable replication of nucleic acids. DNA repair and protection mechanisms have been discovered in all forms of life. However, the vast array of microbes that may harbor novel repair or protection mechanisms, especially bacterial viruses, have not been adequately assessed. Here, we screened a microbial gene library composed primarily of phage open reading frames (ORFs) to uncover elements …