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Ellipticity-Controlled Exceptional Points From Nanoscale Metasurfaces, Benjamin Goldberg Dec 2024

Ellipticity-Controlled Exceptional Points From Nanoscale Metasurfaces, Benjamin Goldberg

McKelvey School of Engineering Graduate Student Theses & Dissertations

Precise control over light polarization is critical for advancing technologies in telecommunica- tions, quantum computing, and image sensing. However, existing methods for manipulating polarization around exceptional points in non-Hermitian systems, have exclusively focused on circular polarization and work with reflected light. To address this limitation, we de- velop a novel metasurface platform with high-Q resonators that enables tunable control of polarization exceptional points across arbitrary ellipticity for transmitted light. Our design uses orthogonally polarized guided mode resonators in a two-layer silicon metasurface, where careful tuning of the dipolar guided mode resonances (DGMRs) and layer spacing allows us to control the …


The Impact Of Food Law Policies On Local Community Empowerment In Indonesia’S Sustainable Food Garden Program, Tiyas Vika Widyastuti, Achmad Irwan Hamzani, Anis Masdurohatun Dec 2024

The Impact Of Food Law Policies On Local Community Empowerment In Indonesia’S Sustainable Food Garden Program, Tiyas Vika Widyastuti, Achmad Irwan Hamzani, Anis Masdurohatun

Indonesia Law Review

This research examines the impact of food law politics on community empowerment and sustainable agriculture in Indonesia, focusing on the Sustainable Food Garden Program (P2L). Utilizing a normative juridical analysis, it explores how legal frameworks can support or obstruct community-led agricultural initiatives. The study highlights the empowering effect of laws aligned with community goals and the challenges arising from legislation favoring industrial agriculture. It proposes legal reforms to address ambiguities and barriers, such as clarifying land tenure rights and simplifying organic certification processes. Recommendations aim to foster a legal environment conducive to sustainable, community-driven agriculture, enhancing food security and environmental …


Engineering Faculty Perceptions On Student-Use Of Generative Artificial Intelligence (Gai) In Course Completion, Michaela Harper Dec 2024

Engineering Faculty Perceptions On Student-Use Of Generative Artificial Intelligence (Gai) In Course Completion, Michaela Harper

All Graduate Theses and Dissertations, Fall 2023 to Present

Computer science and engineering faculty often argue whether students should be allowed to use GAI tools, such as ChatGPT, or banned from using them for fear of decreasing learning and workforce quality. This research gathers and reports engineering and computer science faculty members’ perceptions, opinions, and recommendations for GAI use in higher education. Faculty members agree that these technologies are here to stay and must be understood to address GAI in college and university courses. However, their willingness to implement GAI into their courses varied based on prior experience in industry and with the technology itself. Those with very limited …


Agriculture In The Urbanizing Chesapeake Bay Watershed: Views On Water Quality, Agricultural-Related Conflicts, And The Adoption Of Nutrient Management Plans, Edem Avemegah Dec 2024

Agriculture In The Urbanizing Chesapeake Bay Watershed: Views On Water Quality, Agricultural-Related Conflicts, And The Adoption Of Nutrient Management Plans, Edem Avemegah

All Graduate Theses and Dissertations, Fall 2023 to Present

This dissertation analyzes Chesapeake Bay Watershed (CBW) agriculture by exploring residents' views on water quality issues, agriculture-related conflict, and farmers' adoption of nutrient management plans. The following questions were asked: What is the level of concern among non-agricultural and agricultural residents about water quality issues in local streams and waterways and the CBW, and to whom do the two groups attribute water quality problems? What are nonfarming residents' and farmers' levels of support for various interventions outlined in previous research on water quality issues in local streams and waterways and the CBW? What is the level of nonfarming residents' and …


Ecological Interactions Of Cougars, Deer, And Wild Pigs In The Central Coast Range, California, Mitchell A. Parsons Dec 2024

Ecological Interactions Of Cougars, Deer, And Wild Pigs In The Central Coast Range, California, Mitchell A. Parsons

All Graduate Theses and Dissertations, Fall 2023 to Present

Wild pigs are an introduced species in the Americas that negatively affect ecosystems in many ways. Previous research has documented their negative effects on water quality and vegetation and their potential to spread disease among wildlife, domestic animals, and humans. However, how wild pigs affect predator-prey interactions between native wildlife has received little attention. This research explores multiple interactions between wild pigs, a native predator (cougars), and a native prey (black-tailed deer). First, I studies cougar diet to understand how frequently pigs are used as prey. During this project, I also placed wildlife cameras at cougar killed prey to monitor …


Designing Technology-Enriched Learning Environments: The Effects Of An Agent-Based Computer Model On Biology Students' Understanding Of The Covid-19 Pandemic And The Nature Of Models In Science, April Sullivan Dec 2024

Designing Technology-Enriched Learning Environments: The Effects Of An Agent-Based Computer Model On Biology Students' Understanding Of The Covid-19 Pandemic And The Nature Of Models In Science, April Sullivan

All Graduate Theses and Dissertations, Fall 2023 to Present

Science education researchers have called for increased attention to the science practice of modeling to engage students in authentic scientific inquiry. A major challenge to integrating the modeling practice into science instruction is that students tend to conceptualize models as static end-products of research rather than generative tools for theory-building. Engaging students in using computer models, specifically agent-based computer models (ABMs), to explain and predict scientific phenomena could improve students' understanding of models in science. In this design-based research project I investigate the effects of an ABM-supported learning environment on high-school biology students' understanding of the COVID-19 pandemic and the …


Molecular Pathways Of Odontogenic Keratocysts: A Systematic Review, Paolo Boffano, Francesca Neirotti, Matteo Brucoli, Muhammad Ruslin Dec 2024

Molecular Pathways Of Odontogenic Keratocysts: A Systematic Review, Paolo Boffano, Francesca Neirotti, Matteo Brucoli, Muhammad Ruslin

Journal of Dentomaxillofacial Science

The odontogenic keratocyst (OKC) stands out as one of the most prevalent odontogenic tumors. Since its initial description, numerous studies have delved into various aspects of this lesion, aiming to unravel its distinctive biological behavior.

Recent investigations have specifically focused on the molecular aspects of OKC, shedding light on its biological characteristics. Substantial differences at the molecular level between OKC and other odontogenic cystic lesions indicate a distinct biological origin. Genetic and molecular research in the realm of odontogenic tumors, particularly OKC, has contributed significantly to the growing knowledge and understanding of their physiopathological pathways. The molecular findings may open …


Effectiveness Of Cabbage (Brassica Oleracea Var. Capitata L.) Against Streptococcus Mutans, Staphylococcus Aureus And Porphyromonas Gingivalis Bacteria, Irene E. Rieuwpassa, Nurlindah Hamrun, Maria Tanumihardja, Juni J. Nugroho, Risfah Yulianty, Sherlie Diana, Yogie M. Arief, Nur F. Said, Rezky A. Putri, Boy M. Bachtiar, Heni Susilowati, Retno I. Roestamadji Dec 2024

Effectiveness Of Cabbage (Brassica Oleracea Var. Capitata L.) Against Streptococcus Mutans, Staphylococcus Aureus And Porphyromonas Gingivalis Bacteria, Irene E. Rieuwpassa, Nurlindah Hamrun, Maria Tanumihardja, Juni J. Nugroho, Risfah Yulianty, Sherlie Diana, Yogie M. Arief, Nur F. Said, Rezky A. Putri, Boy M. Bachtiar, Heni Susilowati, Retno I. Roestamadji

Journal of Dentomaxillofacial Science

Objective: Therefore, this study was aimed at examining the inhibition of green cabbage and purple cabbage against oral pathogenic bacteria and knowing the nitrate content and the theoretical benefits of nitrate in cabbage as a prebiotic material that supports oral and dental health including systemic body health by lowering blood pressure.

Material and Methods: The type of research to be used is laboratory experimental with the post test only control group. Preparation of green cabbage and purple cabbage extracts with maceration technique. Dilution was carried out so that the concentration of green cabbage and purple cabbage extracts was …


Potential Ethanol Extracts Of Super Red Dragon Fruit Peel And Flesh For Detecting Dental Plaque, Euis R. Yuslianti, Dewi Li. Nasution, Nadya S. Pramita Dec 2024

Potential Ethanol Extracts Of Super Red Dragon Fruit Peel And Flesh For Detecting Dental Plaque, Euis R. Yuslianti, Dewi Li. Nasution, Nadya S. Pramita

Journal of Dentomaxillofacial Science

Objective: Dental plaque is a collection of microorganisms that adhere to surface of tooth and can cause various health problems in oral cavity. To detect plaque on surface of teeth, a coloring agent such as a disclosing solution is needed. As an alternative ingredient that does not harm, this study used super red dragon fruit peel and flesh (Hylocereus costaricensis) which is high levels of anthocyanins and natural coloring agents that can be used as alternative materials for detecting plaque on surface of tooth.

Material and Methods: The research methode were quasi-experimental design research with a post-test control …


Chitosan Black Soldier Fly (Hermetia Illucens) Pupae Can Improve Macrophages And Fibroblast Post-Extraction Teeth, Renie K. Dewi, Sri Oktawati, Asdar Gani, Eko Suhartono, Zakiah H. Noor, Nurlindah Hamrun, Shahida M. Said, Beta W. Oktiani Dec 2024

Chitosan Black Soldier Fly (Hermetia Illucens) Pupae Can Improve Macrophages And Fibroblast Post-Extraction Teeth, Renie K. Dewi, Sri Oktawati, Asdar Gani, Eko Suhartono, Zakiah H. Noor, Nurlindah Hamrun, Shahida M. Said, Beta W. Oktiani

Journal of Dentomaxillofacial Science

Objective. The objective of this study was to quantify the number of macrophages and fibroblasts involved in the post dental extraction socket healing.

Material and Methods. Chitosan BSF pupae was made into a gel preparation. Eighteen Male Cavia cobaya were divided into two groups (n = 9), control and treatment groups. BSF pupae chitosan gel was applied to the post-extraction tooth socket in the treatment group, while none was applied to the control group. The samples were decapitated on the 2nd, 3rd, and 5th days by cutting the mandibular bone for histopathological examination, which was …


Mental Index, Antegonial Index, And Mandibular Cortical Index For Assessment Of Bone Quality Using Panoramic Radiograph, Supriyadi, Swasthi Prastyarini, Lusi Hidayati, Agus Sumono, Yohana M. Penga, Susi W. Asih Dec 2024

Mental Index, Antegonial Index, And Mandibular Cortical Index For Assessment Of Bone Quality Using Panoramic Radiograph, Supriyadi, Swasthi Prastyarini, Lusi Hidayati, Agus Sumono, Yohana M. Penga, Susi W. Asih

Journal of Dentomaxillofacial Science

Background: Several indices for measuring the thickness of the mandibular cortex using a panoramic radiograph have been developed. Indices enable measurements to assess bone quality (bone mineral density/BMD). This study aims to identify bone quality through mental index (MI), antegonial index (AI), and mandibular cortical index (MCI) measurements using a panoramic radiograph. 

Materials and method: The observational study used a cross-sectional research design. The population was panoramic radiographs of patients in the Radiology installation of the University of Jember Dental Hospital. The samples consisted of 87 panoramic radiographs that met the criteria inclusion: Region of Interest (ROI), i.e., …


Impact Of Irrigation Systems On Water Use And Water Productivity: A Case Study Using Aquacrop In Khartoum, Sudan, Abdalhakam Almagzoop Dec 2024

Impact Of Irrigation Systems On Water Use And Water Productivity: A Case Study Using Aquacrop In Khartoum, Sudan, Abdalhakam Almagzoop

Department of Agricultural and Biological Systems Engineering: Masters Project Reports

Water scarcity significantly challenges agricultural productivity in arid regions like Khartoum, Sudan. This study evaluates the impact of three irrigation systems—furrow, sprinkler, and surface drip—on the water use and productivity of sorghum (Sorghum bicolor L.) under different climatic conditions using the AquaCrop model. Simulations were conducted for three representative years: a wet year (2022), a normal year (2015), and a dry year (2018). The results demonstrate that irrigation substantially improved water use efficiency and crop yield compared to non-irrigated (rainfed) conditions. Rainfed crops resulted in lower biomass, harvest index, and yield, particularly in the dry year, highlighting the importance …


Enhancing Water Sustainability In North Africa: Literature Review And Synthesis Of Current Knowledge Gaps In Sudan, Osman M. A. Adam Dec 2024

Enhancing Water Sustainability In North Africa: Literature Review And Synthesis Of Current Knowledge Gaps In Sudan, Osman M. A. Adam

Department of Agricultural and Biological Systems Engineering: Masters Project Reports

This study delves into the critical role of groundwater in addressing global water challenges, with a focus on the Nubian Sandstone Aquifer System (NSAS) in north Africa. Groundwater constitutes a source of potable water, irrigation, and industrial use, especially in arid regions where surface water is limited. We analyzed the status of water quantity, withdrawals, recharge, and geological characteristics in the NSAS, specifically in Sudan, Egypt, and Libya. Though the NSAS is largely an untapped resource, water withdrawals from the NSAS in Egypt, Sudan, and Libya are projected to increase substantially from 2000 to 2100 due to population growth, with …


Leveraging Geo-Ai To Evaluate Conservation Land Conditions In Nebraska, Usa, Fnu Jahangeer Dec 2024

Leveraging Geo-Ai To Evaluate Conservation Land Conditions In Nebraska, Usa, Fnu Jahangeer

Community and Regional Planning Program: Theses

Wetlands are among the most vital natural resources, offering extensive ecosystem services that benefit human societies. However, human activities and disturbances have led to widespread wetland degradation and loss worldwide. Key factors contributing to this degradation include pollution, exploitation of biological resources, modifications to natural systems, and agricultural and aquacultural practices. This study examines wetland conservation efforts in Nebraska, focusing on three main areas: (1) AI-Driven Applications in Google Earth Engine for Surface Water Monitoring, Assessment, and Management; (2) Assessing Wetland Hydrological Performance under Three Conservation Programs in Nebraska through AI-Driven Google Earth Engine Analysis; and (3) Identifying Potential Wetland …


Artificial Intelligence And Cracks In The Foundation Of Intellectual Property, Robin Feldman Dec 2024

Artificial Intelligence And Cracks In The Foundation Of Intellectual Property, Robin Feldman

UC Law Journal

Our implicit image of progress and the standards we use to calibrate human contribution to progress are quietly at risk from the onslaught of artificial intelligence (AI). AI has the potential to significantly shrink the pool of creative work that is protectable by intellectual property (IP) law and the range of information that is protectable, as well as shrinking the value proposition of IP regimes themselves.

As society faces this changing landscape, we must tread carefully to distinguish fears about AI from the task of defining the boundaries of intellectual property, whose theoretic concepts aren’t designed to bear such weighty …


The Influence Of Trauma History On Opiate Use Disorder In An Urban Treatment Facility In Pennsylvania, Roxanne Jeffries-Baxter, Christopher J. Burant, Joachim G. Voss Dec 2024

The Influence Of Trauma History On Opiate Use Disorder In An Urban Treatment Facility In Pennsylvania, Roxanne Jeffries-Baxter, Christopher J. Burant, Joachim G. Voss

Student Scholarship

Background: Opioid use disorder is one of the most severe forms of substance use disorder and is associated with high morbidity and mortality. Opiate overdose deaths in the US are increasing every year, claiming over 100,000 lives in 2022. Psychological trauma exposure and post-traumatic stress disorder are major health problems in the United States and may contribute to the development of an opiate use disorder. The purpose of this study was to examine the association of psychological trauma exposure and post-traumatic stress disorder with opiate use disorder. Methods: This study used a retrospective design with a convenience sample size of …


Lgbtq+ College Students’ Willingness To Access Campus Health Services At A Midsized, Urban Christian University: A Study On Disparities, Samual J. Piatt, Christian Williams, Frecia Gonzalez Dec 2024

Lgbtq+ College Students’ Willingness To Access Campus Health Services At A Midsized, Urban Christian University: A Study On Disparities, Samual J. Piatt, Christian Williams, Frecia Gonzalez

SPARK Symposium Presentations

Introduction

LGBTQ+ college students face inequitable health outcomes in both mental health and physical health versus non-LGBTQ+ counterparts (The Trevor Project, 2023), (Brittain et Dinger, 2015). LGBTQ+ students experience higher unwillingness and disparities in care access due to negative perceptions of and experiences with UHS providers (Hood et al, 2019). Research indicates that better provider LGBTQ+ cultural awareness contributes to a more affirming space which in turn benefits LGBTQ+ healthcare (Parmenter et al, 2020), (Prasad et al, 2023).

Methods

A 2024 cross-sectional study assessed the comfort levels of LGBTQ+ college students in accessing student health services, explore how affirming healthcare …


Polymeric Sumo-2/3 Chain Signals Are Antagonistically Regulated By The Sumo-Targeted Ubiquitin E3 Ligase Rnf4 And The Sumo-Specific Isopeptidase Senp6, Shaniah A. Irving M.A., Xiang-Dong Zhang Ph.D. Dec 2024

Polymeric Sumo-2/3 Chain Signals Are Antagonistically Regulated By The Sumo-Targeted Ubiquitin E3 Ligase Rnf4 And The Sumo-Specific Isopeptidase Senp6, Shaniah A. Irving M.A., Xiang-Dong Zhang Ph.D.

Biology Theses

Polymeric SUMO-2/3 chain modification is critical for chromosome segregation, DNA damage repair, genome stability, stress responses, and protein degradation. However, how these signals are regulated remains poorly understood. Both the SUMO-targeted ubiquitin E3 ligase (STUbL) RNF4 and the SUMO-specific isopeptidase SENP6 recognize poly-SUMO-2/3 chains through multiple SUMO-interacting motifs (SIMs). RNF4 contains four tandem SIMs within a short (~80 amino acids) region, whereas SENP6 possesses eight SIMs spanning a much larger (~500 amino acids) domain.

Our preliminary results show that overexpressing an RNF4 N-terminal fragment containing four tandem SIMs (wild type, WT), but not an inactive SIMs mutant (Mut), increases levels …


Soybean Seed Yield Distribution Within The Canopy As Affected By Nitrogen Supply, Lucia Bonfanti Dec 2024

Soybean Seed Yield Distribution Within The Canopy As Affected By Nitrogen Supply, Lucia Bonfanti

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

Soybean [Glycine max (L.) Merr.] seed yield is influenced by the seasonal availability of resources (i.e., nutrients, light, and water). While nitrogen (N) supply is becoming a soybean yield-limiting factor, the N-induced effect in seed yield components is still unclear. The objective of this research was to assess the effect of N supply on soybean yield components distribution within the canopy. A Full-N treatment, which provided the crop with ample N supply, was compared against a Zero-N treatment in which the crop relied on soil N and biological N fixation at nine high-yielding irrigated soybean environments in Nebraska, with …


Leveraging Within-Field Spatial Variability To Optimize Soybean Yield, Seed Quality, And Profitability, Marina Marly Dalla Betta Dec 2024

Leveraging Within-Field Spatial Variability To Optimize Soybean Yield, Seed Quality, And Profitability, Marina Marly Dalla Betta

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

Optimizing yield and seed quality in soybean production is critical for both profitability and meeting market demands. However, within-field variability in soil properties poses a challenge in determining optimal management strategies to maximize soybean yield, seed quality, and profitability. This work aimed to evaluate the spatial variability of soybean fields to optimize soybean seeding rates, seed quality, and profitability. Two case studies were used to carry over this research. The first study looked at the optimal economical site-specific soybean seeding rates using 11 on-farm precision experiments across Nebraska. The second study looked at the protein and oil variability within 22 …


Case Brief: In Re R.A.F.–Beware Of The "Haunting Specter", Sam W. Scheipers Dec 2024

Case Brief: In Re R.A.F.–Beware Of The "Haunting Specter", Sam W. Scheipers

North Carolina Law Review

No abstract provided.


Examination Of The Relationship Between Algal And Mussel Populations In Streams, Haarika Hebbur Dec 2024

Examination Of The Relationship Between Algal And Mussel Populations In Streams, Haarika Hebbur

Honors Projects

Due to the ecological importance of both mussel and algal populations, understanding their interactions is critical for further studies in the field. This literature review will explore the functions of both organisms within stream ecosystems, followed by an observational study. The study is designed to evaluate the potential interactions between algal biomass and mussel populations using chlorophyll a concentration as a tool for algal abundance measurement.


Teachers’ Life Experience Of Trauma And Its Impact In The Classroom, Casey Voelz Dec 2024

Teachers’ Life Experience Of Trauma And Its Impact In The Classroom, Casey Voelz

All-Inclusive List of Electronic Theses and Dissertations

The purpose of this qualitative study was to determine if teachers’ lived experiences of trauma impact practices, relationships, and responses to student behaviors in the classroom. The common themes could allow colleges, school districts, and school leaders to reflect, develop, or improve access to therapeutic interventions and teacher self-discovery in the areas of self-awareness, self-regulation, and emotional intelligence. This qualitative study involved obtaining data from the Indiana Department of Education. The Indiana Department of Education provided email addresses for superintendents for public schools in Indiana. Superintendents received an email requesting teacher participation. If approved, teachers received the ACE survey. From …


Evaluation Of Pierce’S Disease-Resistant Grapevine Cultivars In Upstate South Carolina, Annie Bruno Dec 2024

Evaluation Of Pierce’S Disease-Resistant Grapevine Cultivars In Upstate South Carolina, Annie Bruno

All Theses

Interest in wine grape production is increasing in South Carolina, but Pierce’s Disease (PD) caused by the xylem-limited bacteria Xylella fastidiosa (Xf) is a major limiting factor. Xf is spread by sap-sucking insect vectors in the Cicadellidae family such as sharpshooters. In the United States, Xf has become endemic to the southeast as global temperatures rise, causing winter temperatures to increase, which allows the bacteria to survive year-round. However, PD-resistant grapevine hybrid cultivars have become available through breeding V. vinifera genes with native American Vitis species that are resistant to Xf. In this study, the PD-resistant grapevine …


Evaluating The Roles Of Pollinators In Shaping The Floral Color Variation Of Phacelia Dubia, Katherine Riddle Dec 2024

Evaluating The Roles Of Pollinators In Shaping The Floral Color Variation Of Phacelia Dubia, Katherine Riddle

All Theses

Floral color variation within a species is a common occurrence and its maintenance has been a long-standing question in evolutionary biology. Differences in flower color between populations can be shaped by pollinator-mediated selection. Pollinators can exhibit innate and learned preferences for color that may influence floral color variation. These preferences may be molded by the visual environment in which pollinators forage. Most current understanding of how pollinators shape floral color variation involves dramatic differences in dominant pollinators between populations (e.g., hawkmoth vs. bee) and most behavioral work utilized model pollinators like honeybee and bumble bee. However, less is known about …


Informing Management Of American Shad (Alosa Sapidissima) In The Carolinas: Evaluating Novel Fish Passage Approaches And Acoustic Tracking Methods, Margaret Gaither Dec 2024

Informing Management Of American Shad (Alosa Sapidissima) In The Carolinas: Evaluating Novel Fish Passage Approaches And Acoustic Tracking Methods, Margaret Gaither

All Theses

Acoustic telemetry is a valuable tool for fisheries scientists to study the movements and migratory behaviors of aquatic organisms. A critical assumption of this method is that tagged fish exhibit similar behaviors and survival rates as their untagged counterparts. To investigate this, we conducted a 12-week laboratory study on adult American Shad (Alosa sapidissima) using gastroesophageal insertion of acoustic transmitters. We implanted 80 fish with dummy transmitters and monitored tag retention and survival. Our analysis, employing a mixed effects Cox’s proportional hazards model, revealed no significant differences in survival between tagged and control fish, regardless of sex. Additionally, …


On Humans, Hogs, And Habitat: How Landscape Features And Vegetation Influence Wild Hog (Sus Scrofa) Detection On Private Lands And Using Existing Wild Hog Outreach Websites To Create An Effective Website For South Carolina, Andrew Jamison Dec 2024

On Humans, Hogs, And Habitat: How Landscape Features And Vegetation Influence Wild Hog (Sus Scrofa) Detection On Private Lands And Using Existing Wild Hog Outreach Websites To Create An Effective Website For South Carolina, Andrew Jamison

All Theses

Invasive species are a source of human conflict with wildlife on a global scale and exist to the detriment of native wildlife species. Invasive species often possess the ability to respond rapidly to change and they often exist alongside humans. Wild hogs (Sus scrofa) are perhaps one of the most infamous examples of an invasive species. The spread of wild hogs necessitates effective communication with the public being impacted by them, as well as a continuation of research to learn more about wild hog behavior to promote effective management. Chapter 1 focuses on how we created a website …


Investigation Of Chondrogenesis, Myogenesis, And Osteogenesis After 2,4-Dtbp, 2-Bp, 4-Bp, 3,5-Dtbc Exposure In Zebrafish, Haley Brashears Dec 2024

Investigation Of Chondrogenesis, Myogenesis, And Osteogenesis After 2,4-Dtbp, 2-Bp, 4-Bp, 3,5-Dtbc Exposure In Zebrafish, Haley Brashears

All Theses

Synthetic phenolic antioxidants (SPAs) are used in personal care products, food packaging, and water pipes, common SPAs include 2,4-di-tert-butylphenol (2,4-DTBP), 2-tert-butyl phenol (2-BP), and 4-tert-butyl phenol (4-BP). These compounds are detected in the environment and in human biological samples. 2,4-DTBP has been detected in cord plasma, placenta, and breast milk samples. This drives the concern regarding developmental toxicity. In human iPS cells 2,4-DTBP impairs differentiation into somites and osteoblasts. Other SPAs, like 2,6-di-tert-butyl-hydroxytoluene caused increased rates of malformations including yolk and pericardial edema, and spinal curvature in 5-day post fertilization (dpf) zebrafish. …


A Drosophila Model Of Mucopolysacchridosis Iiia, Rebecca Bishop Dec 2024

A Drosophila Model Of Mucopolysacchridosis Iiia, Rebecca Bishop

All Theses

Mucopolysaccharidosis IIIA (MPS IIIA) is a rare lysosomal storage disorder that arises from inability to break down heparan sulfate (HS) because of mutations in the N-sulfoglucosamine sulfohydrolase (SGSH) gene. We used a deletion mutant of the Drosophila melanogaster Sgsh gene along with three point mutations analogous to mutations observed in patients (S64W, L89P, S301P) to show an increase in the average percent of area with lysosomal puncta in the fly brains of our mutants using Lysotracker. RNA sequencing of brains of mutant and control flies showed 441 (Knockout), 337 (S64W), 155 (L89P), and 96 (S301P) differentially expressed …


Influence Of Hygrothermal Conditions Of The Bistability Of Asymmetric Carbon Fiber Laminate Composites, Celia Hill Dec 2024

Influence Of Hygrothermal Conditions Of The Bistability Of Asymmetric Carbon Fiber Laminate Composites, Celia Hill

All Theses

Carbon fiber-reinforced polymer (CFRP) laminates have widespread use in many industries because of their exceptional strength-to-weight ratio. Carbon fiber laminates following an asymmetric layup orientation can exhibit bistability meaning the laminate can exist at two stable geometric configurations. The morphing characteristics of bistable CRFP has a growing level of interest because of its potential in various applications including space aircraft structures for easy repair, automotive structures for energy dissipation and ergonomics, robotics for flexible motion and energy harvesting. Existing research shows that both moisture and temperature affect the material properties and behavior of CFRP laminates, however, the influence of moisture …