Digital Commons Network^™

Potential Ethanol Extracts Of Super Red Dragon Fruit Peel And Flesh For Detecting Dental Plaque, Euis R. Yuslianti, Dewi Li. Nasution, Nadya S. Pramita

Journal of Dentomaxillofacial Science

Objective: Dental plaque is a collection of microorganisms that adhere to surface of tooth and can cause various health problems in oral cavity. To detect plaque on surface of teeth, a coloring agent such as a disclosing solution is needed. As an alternative ingredient that does not harm, this study used super red dragon fruit peel and flesh (Hylocereus costaricensis) which is high levels of anthocyanins and natural coloring agents that can be used as alternative materials for detecting plaque on surface of tooth.

Material and Methods: The research methode were quasi-experimental design research with a post-test control …

Sedimentary Characteristics Of Flood Deposits In Coastal And Fluvial Environments: Examples From Washover Fans (North Carolina, Usa) And Floodplain Deposits (Mississippi, Usa), Shara Gremillion

Dissertations

Extreme flooding from severe and prolonged meteorological events and / or overbanking rivers are some of the most deadly and expensive disasters globally, impacting millions of lives, the environment, and property. People living in vulnerable areas, such as near coasts and rivers, are the first to be impacted with effects of these flood hazards. Scientific studies and their results can aid communities and officials in planning and preparing for those flood impacts. In this three-part study, flood impacts from coastal storms in North Carolina, and flooding along the Mississippi River (MSR) in the state of Mississippi, USA are assessed from …

Apoa2 Increases Cholesterol Efflux Capacity To Plasma Hdl By Displacing The C-Terminus Of Resident Apoa1, Snigdha Sarkar, Jamie Morris, Youngki You, Hannah Sexmith, Scott E. Street, Stephanie M. Thibert, Isaac K. Attah, Chelsea M. Hutchinson Bunch, Irina V. Novikova, James E. Evans, Amy S. Shah, Scott M. Gordon, Jere P. Segrest, Karin E. Bornfeldt, Tomas Vaisar, Jay W. Heinecke, W. Sean Davidson, John T. Melchior

Saha Cardiovascular Research Center Faculty Publications

Abstract The ability of high-density lipoprotein (HDL) to promote cellular cholesterol efflux is a more robust predictor of cardiovascular disease protection than HDL-cholesterol levels in plasma. Previously, we found that lipidated HDL containing both apolipoprotein A-I (APOA1) and A-II (APOA2) promotes cholesterol efflux via the ATP-binding cassette transporter (ABCA1). In the current study, we directly added purified, lipid-free APOA2 to human plasma and found a dose-dependent increase in whole plasma cholesterol efflux capacity. APOA2 likewise increased the cholesterol efflux capacity of isolated HDL with the maximum effect occurring when equal masses of APOA1 and APOA2 coexisted on the particles. Follow-up …

Untargeted Lipidomics Reveals Novel Hdl Metabotypes And Lipid-Clinical Correlates, Peer W. F. Karmaus, Scott M. Gordon, Marcus Y. Chen, Alison A. Motsinger-Reif, Rodney W. Snyder, Timothy R. Fennell, Suramya Waidyanatha, Reshan A. Fernando, Alan T. Remaley, Michael B. Fessler

Saha Cardiovascular Research Center Faculty Publications

Plasma high-density lipoprotein (HDL), originally studied for its role in lipid transport, is now appreciated to have wide-ranging biological functions that become defective during disease. While >200 lipids have collectively been detected in HDL, published HDL lipidomic analyses in different diseases have commonly been targeted to prespecified subsets of lipids. Here, we report the results of untargeted lipidomic analysis of HDL isolated from 101 subjects referred for computed tomographic coronary imaging for whom multiple additional clinical and lipoprotein metadata were measured. Unsupervised clustering of the total HDL lipidome revealed that the subjects fell into one of two discrete groups, herein …

Differentiating Mycosis Fungoides Lesions From Their Mimickers Clinically And Histologically: A Single Tertiary Center Retrospective Analysis In Saudi Arabia, Fatimah M. Budair, Ahmed A. Alsayyah, Omar M. Alakloby

Saudi Medical Journal

Objectives: To identify the clinical and histological features of MF that can assist in distinguishing MF from MF-mimicking cases. Although mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma, clinicopathological correlations are required to establish an accurate diagnosis, which are currently lacking. Methods: This retrospective observational study evaluated the clinical presentations, characteristics, and histological features of 56 patients with suspected MF who presented to our clinic between January 2018 and August 2022. Immunohistochemistry was performed, and the loss of CD5 and CD7 T-cells and T-cell receptor rearrangement was evaluated. Results: Overall, 34 patients were diagnosed with MF, …

Vavanga, Vavalo, And Fakakaukau With Vā-Tā, Siosiua F.P. Lafitani

Pacific Studies

This article addresses the profound cognitive and cultural significance of vavanga (contemplation) and vavalo (contemplation), which are contempla- tive frameworks deeply rooted in the concept of vā (space) within Tongan language and culture. These frameworks serve as gateways to expansive cogni- tive exploration, stretching the boundaries of imagination and contemplation. Fakakaukau (thinking), double or dual actor (named because it bridges the realms of cognition and practicality), uses instrumental concepts such as fifili (inquisitiveness) and fekeli (meticulous exploration) to navigate the landscapes of inquiry. Throughout this exploration, a critical distinction emerges between tā as tempo and the cognitive concepts of contemplation …

Modeling Instrument Design Risks In Medical Device Reprocessing, Manuel Andres Gutierrez

All Dissertations

Medical device reprocessing is an essential practice in healthcare delivery. While FDA regulations require device manufacturers to develop and validate reprocessing procedures, the increasing complexity of medical device designs and their use environments can increase the risks of inadequate reprocessing and associated device malfunctions and potential patient injury. While some design features present known difficulties for reprocessing, critical information needed to define relative risks or feature-specific parameters that increase or decrease risks of inadequate reprocessing is lacking. There is an urgent need for tools to quantify and predict reprocessing risks associated with design features used in surgical instruments.

The broad …

Prevalence Of Autism Spectrum Characteristics In Students Taking Undergraduate Computing Courses, Rachel Michaela Mettenbrink

School of Computing: Dissertations, Theses, and Student Research

The incidence rate of autism spectrum condition (ASC) has increased significantly in recent decades, as awareness of the condition and its impacts increases amongst clinicians, parents, and the general population. Medical literature has proposed that there may be a relationship between ASC and participation in the computing field. This study tests for the prevalence of autism spectrum condition traits measured by delivering the Autism Spectrum Quotient (AQ) to a population of undergraduate computer science students. We examine the relationships between AQ scores and students taking undergraduate computer science classes, sex, socioeconomic status, and parents in the computing industry. Additionally, we …

Fragments Of Fire: Essays On Womanhood, Family, And Environment, Valerie Rose Palacios

LSU New Orleans Theses and Dissertations

Fragments of Fire is a collection of non-fiction, memoir, and opinion essays that navigate themes of gender and societal issues, coming-of-age, generational dynamics, death, and the natural environment. Through an intricate blend of introspection, keen observation, and literary analysis, these essays offer insight into the transformative journey from girlhood to womanhood as experienced by a young Latina. This collection provides a resonant voice that bridges personal narrative with broader cultural and existential questions.

Predicting Different Psychological Profiles Amongst Substance Users., Zach J. Gray

Graduate Theses and Dissertations

Substance use disorders (SUDs) are some of the most prevalent issues facing society. As SUDs are highly individualized in how they manifest, recent work has attempted to classify distinct profiles of drug users to better understand what factors put someone at risk for shifting from casual substance use to developing a substance use disorder (SUD). Common risk factors for SUD development include stressor exposure, difficulties with emotion regulation, personality, and risky decision-making. As many of the behaviors that constitute SUDs are exhibited prior to potential diagnosis, developing “profiles” that combine these traits and experiences could eventually predict SUDs. The current …

Encapsulation Of Probiotics By Cellulose Nanocrystal-Alginate Composite Beads For Ph Stimuli-Responsive Delivery, Akrip Jati

Graduate Theses and Dissertations

Microencapsulation has garnered significant interest, with oral probiotics delivery systems showing enormous potential to help restore the gut microbiome. This method holds vast potential to protect and release specific microbial strains to the desired target site (i.e., colon) within the gastrointestinal tract (GIT). However, current encapsulation methodologies, utilizing either synthetic or biological materials as carriers, encounter challenges such as suboptimal encapsulation efficiency, premature probiotic release, and inadequate control over release kinetics. In this work, hydrogel microsphere (HM) composites of different cellulose nanocrystal (CNC) forms (i.e., colloidal (c), and crosslinked (x)) and alginate (ALG) were used as advanced controlled release systems …

(R2098) Dynamic Analysis Of Stochastic Leslie-Gower Biological Predator-Prey Model With Prey Cannibalism, Sada Nand Prasad, Itendra Kumar Universiry Of Delhi, India, Pawan Kumar

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, we study the dynamical analysis of a stochastic Leslie–Gower biological predator– prey model. Earlier, the Leslie–Gower model was studied in the context of biological systems, including cases involving cannibalism. In our model, we investigate the dynamic properties of a stochastic Leslie–Gower predator–prey ecological system using the stability of invariant measures on invariant sets, where the invariant measures are shown to be ergodic. We also conduct a threshold analysis to study the stochastic persistence and extinction of species. Stochastic bifurcation is also examined. The theoretical results are supported by numerical simulations and examples. Intra-species competition is considered and …

Exploring The Therapeutic Benefits Of Dance In The Academic Schedule: The Effects On Stress Among High School Students, Amanda Polanowski

Master's Theses

The purpose of this study was to gain insight into the minds of dance students about the stress they experienced as a result of their academic schedules and extracurriculars. The following research questions informed this study:

Q1 Does incorporating dance into the academic schedule lower stress in high school students?

Q2 In what mental state are students before and after taking dance class?

Q3 Does dance provide mental health benefits for high school students?

Student stress was evaluated before the study using a questionnaire as well as before and after each dance class through surveys. Eighteen students participated in a …

Assessing Impact Risk To Tropical Marine Ecosystems From Human Activities With A Southeast Asian Example, Fiona Culhane, Melanie C. Austen, Matthew Ashley, Jonson Javier, Sui Hyang Kuit, Nguyen Phuc Hung, Hau Duc Tran, Radisti A. Praptiwi, Sainal Sainal, Eva Justine, Prawesti Wulandari, Stefanie Broszeit, Jean Beth Jontila, Sofia Johari, Lota Creencia, Amy Yee Hui Then, Lea Janine Gajardo, Carya Maharja, Hong Ching Goh, Wan Mohd Syazwan, Yang Amri Affendi, Lê Ngọc Thảo, Jito Sugardjito, Tom Mullier, Olivia Langmead

School of Biological and Marine Sciences

Society relies on intact marine ecosystems for ecosystem services such as nutrition, livelihoods, health and well-being. Yet, to obtain these benefits, we carry out activities, introducing pressures to ecosystems, damaging and degrading habitats and reducing their capacity to optimally provide ecosystem services. Biodiversity and ecosystem services are consequently being lost globally but impact chains from these activities are poorly understood, especially in tropical marine ecosystems. We identified for the first time impact chains linking activities with pressures they introduce in five tropical coastal and marine habitats, specifically through application in four Southeast Asian case study sites. Using expert elicitation based …

Incorporating The Pcl-5 Self Assessment Tool In The Treatment Of Post Traumatic Stress Disorder Using Virtual Reality Therapy, Janette Sanchez

Doctor of Nursing Practice

Background. Post-traumatic stress disorder occurs when individuals experience a traumatic event causing symptoms of depression, anxiety, and cognitive difficulties (Sadock et al., 2017). Failure to assess changes in post-traumatic stress disorder symptoms can result in ineffective treatments (Department of Veterans Affairs & Department of Defense, 2023). Purpose. Implement the Post Traumatic Stress Disorder Checklist for DSM-5 screening tool as part of an outpatient clinic’s virtual reality exposure therapy protocol evaluating patients’ perceived effectiveness of virtual reality exposure therapy in post-traumatic stress disorder management. Methods. All staff and providers were educated on the use of the PCL-5 screening tool. Patients were …

Reframing A Data Sharing Mechanism For The Riparian Nations Of Helmand River Basin: Theory Of Planned Behavior Is Revisited, Najibullah Loodin, Gabriel Eckstein, Vijay P. Singh, Rosario Sanchez

Faculty Scholarship

Data and information exchange plays a crucial role in fostering water cooperation between the riparian nations of a shared watercourse. Taking an integrated approach combining Discourse Analysis and Document Analysis, this research aims at elucidating the challenges and the potential opportunities of data and information exchange on the Helmand River, a drought-stricken river basin shared between upstream Afghanistan and downstream Iran. Drawing on the Theory of Planned Behavior (TPB), we offer nuanced perspectives on the data exchange model developed by Wehn. We argue that there are other underlying and essential elements that hinder the meaningful engagement of the riparian nations …

Racial Disparities In Domestic Violence: Analyzing The Intersection Of Race And Gender, Nia Grace Sharp

Honors Theses

This research explores the intersection of race, gender, and the litigation of domestic violence cases in Memphis, Tennessee. This is explored through qualitative research that combines a theoretical framework with structured interviews of criminal defense attorneys. Utilizing a sample of 5 attorneys with recent exposure to domestic violence cases, this study aims to reveal whether or not intimate partner violence is litigated differently across racial lines. This is done through analysis of the treatment of victims depending on race, sentencing rates, and perceptions of credibility within the justice system. The methodology involves five key steps: conducting a literature review to …

Parental Guidance Necessary: A Qualitative Study On The Impacts Of Parenting Styles, Mackenzie Longmire

Honors Theses

This thesis examines the long-term effects of parenting styles and attachment experiences on adult psychological well-being, relational competence, academic aspirations, and self-concept. Through qualitative analysis of semi-structured interviews with three participants from the Chattanooga, Tennessee area, the study investigates how family dynamics—framed by Baumrind’s parenting models and Bowlby’s attachment theory—shape developmental trajectories across the lifespan. Findings indicate that authoritative parenting fosters resilience, empathy, and secure attachments, while authoritarian and avoidant parenting styles often lead to relational hesitancy and diminished self-worth. Emphasizing the value of responsive, balanced parenting, this study underscores its role in promoting emotional security and adaptive coping, with …

Evaluation Of The Etiology Of Recurrent Pregnancy Loss (Rpl): An Explanatory Mixed Methods Study Exploring Obstetrician Gynecologist Clinical Provider Behaviors And Factors Contributing To Incomplete Evaluations, Emelia Grant

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: More than 50% of patients with recurrent pregnancy loss (RPL) are left without explanations for their losses. However, current research suggests that up to 90% of these individuals could receive explanations through evidence-based laboratory testing. Professional guidelines vary in their recommendations for laboratory testing and RPL evaluation, which can contribute to delayed or fragmented care and untreated maternal disease. Inequities in access to genetic testing further complicate the diagnostic landscape of RPL since payor policies often determine which tests are covered, leaving many patients without access due to financial constraints.

Objective: This study aimed to evaluate current practices of …

Teaching Learning Newsletter Vol 4 Issue 2, Sastra Deemed To Be University

TLC Newsletter

No abstract provided.

U-Glide Program Fall 2024, Unf Office Of Undergraduate Research, Unf Graduate School

Undergraduate – Graduate Learning, Inquiry, and Distinctive Experimentation (U-GLIDE) Symposium Programs

No abstract provided.

Young Adults’ Perceptions Of Adverse Childhood Experiences As Context And Causes Of Mental Health Conditions: Observations From The United States, Kathryn Sabella, Ian A. Lane, Murron O'Neill, Natalie Tincknell

Faculty Publications (Peer-Reviewed)

Background

Objective

Participants and setting

Methods …

Spatial-Textural Study Of Siliciclastics In A Navajo Sandstone Carbonate Lens, Christopher L. Rupe

Loma Linda University Electronic Theses, Dissertations & Projects

Flat-lying carbonate deposits in the Lower Jurassic Navajo Sandstone have long been interpreted as interdune lacustrine deposits. This dissertation critically assesses such inference through the study of an exceptionally well-preserved carbonate deposit in the Trough Canyon area, northwest of Moab, Utah. Thickness measurements along multiple cross-sectional exposures were used to construct an isopach map, approximating the original size and lenticular geometry of the deposit. Dip directions were recorded from foreset strata in cross-bed sets stratigraphically overlying the deposit to infer the approximately coeval direction of siliciclastic transport across the carbonate basin. These data sets yielded a contextual framework for studying …

Microplastic Degradation Compared Among Dated Salton Sea Strandlines, Maria Alejandra Roman Medrano

Loma Linda University Electronic Theses, Dissertations & Projects

This thesis investigates the environmental degradation of plastic materials, with a focus on polyethylene terephthalate (PET), through a multi-phase study conducted at the Salton Sea, a closed-basin lake in a semi-arid region of California. The research addresses three core objectives: (1) developing a microplastic (MP) extraction method tailored for clay-rich sediments, (2) characterizing surface degradation of various plastic types, including PET, BoPET, HDPE, LDPE, and EPS, using advanced microscopy and spectroscopy, and (3) examining the long-term weathering of PET through samples collected from dated lake strandlines.

The extraction protocol successfully isolates MPs without oxidation, using ZnCl₂ and extended soaking to …

Characterizing Tropical Forest Structure Using Semivariance And Crown Delineation, Brittani Joy Evon Chapman

Master's Theses and Capstones

The study of terrestrial carbon stocks is essential to understand global carbon cycles and the magnitude of anthropogenic carbon emissions. Forests are significant terrestrial carbon stores, with the above ground biomass of the Brazilian rainforest alone conservatively estimated to contain ten percent of the terrestrial carbon stock (Asner et al., 2001; Drake et al., 2002; Keller et al., 2004; Lloyd et al., 2007; Truehaft et al., 2014; Cushman et al., 2021). The Amazon Basin primarily consists of closed-canopy tropical forest, covering 5.8 x 106 km2 interspersed with substantial portions of cerrado surrounding the Amazon River and its tributaries in the …

Behavioral And Physiological Effects Of Ocean Acidification On Juvenile American Lobsters (Homarus Americanus), Todd Edward Stelling

Master's Theses and Capstones

Increased absorption of anthropogenic carbon dioxide (CO2) into the world’s oceans has resulted in ocean acidification (OA). Acidification induces physiological and behavioral responses from marine invertebrates that vary by taxa. Resilience to OA has been noted in crustaceans, though negative impacts are still reported. It has been shown that the American lobster (Homarus americanus) can be physiologically impacted by acidified conditions. We explored the effects of acidification on the hemolymph chemistry and the foraging behavior of juvenile American lobsters (carapace length, CL, 29 - 52 mm, 42 +/- 1.3 mm). We exposed 28 juvenile lobsters to individual pH values ranging …

Synthesis And Testing Of Peptide Iron Probes In Cell Studies, Fran Gomez

Master's Theses and Capstones

The study of iron within cells has advanced significantly since the Fenton reaction was proposed as a mechanism for ferroptosis. Various chemical probes have been developed for examining iron and reactive oxygen species (ROS), both of which are involved in the Fenton reaction. Iron, the most abundant transition metal in the human body, primarily exists as Fe(II) and Fe(III) in the cellular environment. The labile iron pool (LIP) is suspected to predominantly exist as Fe(II) due to endogenous reductants. Under ferroptotic conditions, Fe(III) produced in the Fenton reaction can be reduced back to Fe(II), even when chelated, re-inducing hydroxyl radical …

Identification Of Lncrnas Involved In The Host Response To Venezuelan Equine Encephalitis Virus Infection, Mahgol Behnia

Biomedical Sciences ETDs

Venezuelan equine encephalitis virus (VEEV) is an enveloped positive-sense RNA virus in the alphavirus genus of the Togaviridea family, that causes encephalitis in humans and equids. Currently no FDA-approved vaccine or treatment is available for human use, emphasizing the importance of studying host-VEEV interaction. lncRNAs are regulatory RNAs involved in modulation of antiviral pathways during viral infections. Here we report differential lncRNAs expression in primary mouse astrocytes and neurons during non-pathogenic (TC-83) but not pathogenic (TrD) VEEV infection. We further demonstrated that suppression of four lncRNAs increased TC-83 replication, with lncRNA small nucleolar RNA host gene 15 (Snhg15) increasing TC-83 …

Timigp: A Computational Framework To Determine The Tumor Immune Microenvironment Associated With Prognosis And Immunotherapy Response, Chenyang Li

Dissertations and Theses (Open Access)

Accumulating evidence has suggested that the tumor immune microenvironment (TIME) drastically impacts cancer patients’ clinical outcomes, including prognosis and immunotherapy response. However, understanding TIME remains challenging due to its complexity and heterogeneity. In this dissertation, we introduce TimiGP (Tumor Immune Microenvironment Illustration based on Gene Pairs), a computational framework designed to address this challenge. Leveraging single-cell RNA-seq (scRNA-seq) and bulk gene expression data alongside clinical information, TimiGP constructs a cell-cell interaction network that elucidates the relationship between immune cell function and relevant clinical outcomes, such as prognosis and treatment response. With immunological insights, these cell-cell interactions also facilitate the development …

The Role Of Wt1 In Müllerian Duct Development, Jace Aloway

Dissertations and Theses (Open Access)

WT1 is a zinc finger transcription factor widely expressed in the urogenital system. Human mutations of WT1 lead to pediatric nephroblastoma as well as frequent differences of sex development (DSDs). Previous studies have suggested that WT1 acts as an activator for Amhr2, a necessary component of typical male differentiation. We used the mouse as a model to investigate the role of WT1 in sex development, where we deleted Wt1 in the Müllerian duct (MD) mesenchyme using a novel conditional null reporter allele, Wt1 flox-RFP. This allele utilizes the Cre-lox system to delete exons 8 and 9 of Wt1 …