Digital Commons Network^™

Induced Systemic Resistance Against Nematodes By Plant Growth-Promoting Microbes In Potatoes, Cole Grannan

Master's Theses

Biofertilizers consist of plant growth-promoting microorganisms that establish symbiotic relationships with plant roots and stems. These beneficial microbes play a crucial role in enhancing plant defenses against various threats including insects, nematodes, and microbial pathogens. The purpose of this study was to investigate the effectiveness of two fungal biofertilizers (an endophytic strain of Beauveria bassiana (BA) and a mixture of arbuscular mycorrhizal (AM) fungi), specifically their ability to induce systemic resistance against plant- parasitic nematodes (PPNs) in potatoes (Solanum tuberosum cv. Masquerade) under controlled greenhouse conditions. The study utilized soil collected from Colorado State University’s San Luis Valley (SLV) Research …

Rape Beyond Fantasy: Exploring The Influence Of Booktok's Erotica And Dark Romance Literature On Young Adult Perceptions Of Consent And Boundaries, Teagan Bailey Fortune

Master's Theses

Advances in technology and media, particularly TikTok, have had a significant impact on the younger generation. BookTok, a community that emerged from TikTok, is a platform where users can promote, share, and discuss book recommendations, using “spice level” or chili emojis to indicate the rating of explicit content. While recommendations often focus on erotica and dark romance fiction, concerns arise when such content glamorizes and normalizes rape culture, especially for young adults (YA). The normalization of toxic relationships can potentially influence YA perceptions of consent and boundaries. This study explores how YA perceive rape culture and consent in erotica and …

Leading Biologics In Pharmacy Practice: The Role Of Pharmacists, Amerah Elshayeb, Emily Austin, Lipika Chablani

Doctoral External Publications

Evaluate the current approaches to handling biologics, identify challenges associated with their storage and preparation, and emphasize the critical role of pharmacy education in ensuring safe and effective management of biologics.

Bad Plants, Heather I. Sullivan

Modern Languages and Literatures Faculty Research

“Bad plants” represent the seemingly unexpected and startling forms of plant power overlooked by many modern, industrialized societies that treat vegetal beings as mere resources instead of animate, world-shaping forces. Since science fiction and fairy tales often explore more openly animistic visions of non-human life, such texts provide ample possibilities for reconsideration by critical plant studies of our human-plant relations both cultural and ecological. For example, both Jack McDevitt’s 2001 science fiction novel, Deepsix, and Ludwig Tieck’s 1799 fairy tale, “Faithful Eckart and Tannhäuser”, feature “bad plants” that bring human beings violently back into the plant cycles they assume they …

Magnetic Resonance Imaging Trackable Pathology-Triggered Polymersomes Toward Enzyme Replacement Theranostics For Gm1 Gangliosidosis, Dorian Foster

All Dissertations

This dissertation investigates the development and optimization of pathology-responsive polymersomes for simultaneous enhanced magnetic resonance imaging (MRI) and enzyme replacement therapy (ERT) in the treatment of GM1 gangliosidosis (GM1). While therapeutic strategies exist for similar, non-neuropathic lysosomal storage disorders, implementation towards GM1 faces significant challenges due to the blood-brain barrier.

Herein, we developed and characterized a range of low molecular weight hyaluronic acid-b-polylactic acid (HA-PLA) polymersomes (PSs) capable of encapsulating therapeutic enzymes in their hydrophilic core. These polymersomes exhibit pathophysiology-triggered responsiveness, degrading in the presence of acidic conditions, which is characteristic of lysosomes, and enzymes such as hexosaminidase A, which …

Soil Data From Spring Run Conservation Area, Dayton, Ohio, Madelaine Gregory, Valerie N. Thurston, Michaela J. Woods, Ryan W. Mcewan

Data Files: Ecosystem Restoration Following Industrial Agriculture

This spreadsheet contains soil data from an experiment in the Spring Run Conservation Area in Dayton, Ohio, USA (39° 46 '42.2"N, 84° 20' 52.5"W). Details of the data collection can be found in the master's thesis "The State of Soil Streamlines Secondary Succession: Remediating Degraded Soils in a Post-Agricultural Field."

The Price Of Precision: Significant Figures And The Student Experience, Ryan Michael Britt

Dissertations

For students pursuing careers in medicine and science, general chemistry is often viewed as a gatekeeper course. Students struggle with general chemistry for a variety of reasons, one of the most common being mathematical difficulties. Compared to other lower division STEM courses, mathematical computation in general chemistry represents a unique challenge for the student due to the special emphasis placed on reporting answers to the proper degree of precision using significant figure (SF) rules. Although these rules feature in nearly every undergraduate chemistry course, their impact on the student experience of learning chemistry has never before been studied.

The purpose …

Azacitidine As Epigenetic Priming For Chemotherapy Is Safe And Well-Tolerated In Infants With Newly Diagnosed Kmt2a-Rearranged Acute Lymphoblastic Leukemia: Children's Oncology Group Trial Aall15p1, Erin M. Guest, John A Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown

Manuscripts, Articles, Book Chapters and Other Papers

Infants less than 1 year old diagnosed with KMT2A-rearranged (KMT2A-r) acute lymphoblastic leukemia (ALL) are at high risk of failure to achieve remission, relapse, and death due to leukemia, despite intensive therapies. Infant KMT2A-r ALL blasts are characterized by DNA hypermethylation. Epigenetic priming with DNA methyltransferase inhibitors increases the cytotoxicity of chemotherapy in preclinical studies. The Children's Oncology Group trial AALL15P1 tested the safety and tolerability of 5 days of azacitidine treatment immediately prior to the start of chemotherapy on day 6, in four post-induction chemotherapy courses for infants with newly diagnosed KMT2A-r ALL. The treatment was well-tolerated, with only …

Metaverse-Powered Basic Sciences Medical Education: Bridging The Gaps For Lower Middle-Income Countries., Syeda Samnita Batool Zaidi, Umer Adnan, Kadriye O. Lewis, Syeda Sadia Fatima

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Traditional medical education often lacks contextual experience, hindering students' ability to effectively apply theoretical knowledge in real-world scenarios. The integration of the metaverse into medical education holds great enormous promise for addressing educational disparities, particularly in lower-middle-income countries (LMICs) accompanied by rapid technological advancements. This commentary paper aimed to address the potential of the metaverse in enhancing basic sciences education within the constraints faced by universities in LMICs. We also addressed learning design challenges by proposing fundamental design elements and a suggested conceptual framework for developing metaverse-based teaching methods.The goal is to assist educators and medical practitioners in comprehensivley …

Oh, My Quad: A Clinical Commentary And Evidence-Based Framework For The Rehabilitation Of Quadriceps Size And Strength After Anterior Cruciate Ligament Reconstruction, Braidy Solie, Mitchell Carlson, Christopher Doney, Michael Kiely, Robert Laprade

Physical Therapy Faculty Research and Publications

Quadriceps weakness after anterior cruciate ligament reconstruction (ACLR) is a well-known phenomenon, with more persistent quadriceps weakness observed after ACLR with a bone-patellar tendon-bone or quadriceps tendon autograft than with a hamstring tendon autograft. Longstanding quadriceps weakness after ACLR has been associated with suboptimal postoperative outcomes and the progression of radiographic knee osteoarthritis, making the recovery of quadriceps size and strength a key component of ACLR rehabilitation. However, few articles have been written for the specific purpose of optimizing quadriceps size and strength after ACLR. Therefore, the purpose of this review article is to integrate the existing quadriceps muscle basic …

“Don’T Bring Your Feminism Here!”: The African Hair Braiding Salon As A Rhetorically Charged Space For Feminist Activism, Efe Plange

Open Access Theses & Dissertations

This project extends scholarship on Black beauty and hair care spaces in the US as rhetorically charged for various forms of activism. It specifically explores the nature of work, conversations and feminist ways of being among a group of braiders working together in an African hair braiding salon to legitimize the African hair braiding salon as a site with unique contributions to this body of work. Grounded in Feminist Geo-criticism and Conversational Rhetoric, the study seeks to make contributions that are relevant to the field of Rhetoric and more specifically the sub-field of feminist rhetorics, African and non-Western feminist rhetorics, …

Advocating For More Personalized And Evidence-Based Approaches In Dental Practice, Integrating Advanced Diagnostic Tools And Innovative Treatments To Enhance Patient Care, Hasanuddin, Acing H. Mude, Muhammad Ikbal, Erni Marlina, Muhammad Ruslin

Journal of Dentomaxillofacial Science

This editorial review highlights a series of studies emphasizing evident discoveries in the diagnosis and treatment of oral diseases. The first report addresses a rare case of unicystic ameloblastoma located in the maxillary sinus, highlighting the need of histological analysis for precise identification despite deceptive radiographic characteristics. A different example examines dentigerous cysts, highlighting diagnostic problems stemming from unusual appearances, finally clarified by histological assessment. The effectiveness of sclerotherapy with hypertonic saline for treating parotid sialocele is examined, indicating it as a safe and efficacious therapeutic alternative. The influence of anemia on pediatric drug-induced erythema multiforme is examined, highlighting the …

Chitosan Black Soldier Fly (Hermetia Illucens) Pupae Can Improve Macrophages And Fibroblast Post-Extraction Teeth, Renie K. Dewi, Sri Oktawati, Asdar Gani, Eko Suhartono, Zakiah H. Noor, Nurlindah Hamrun, Shahida M. Said, Beta W. Oktiani

Journal of Dentomaxillofacial Science

Objective. The objective of this study was to quantify the number of macrophages and fibroblasts involved in the post dental extraction socket healing.

Material and Methods. Chitosan BSF pupae was made into a gel preparation. Eighteen Male Cavia cobaya were divided into two groups (n = 9), control and treatment groups. BSF pupae chitosan gel was applied to the post-extraction tooth socket in the treatment group, while none was applied to the control group. The samples were decapitated on the 2^nd, 3^rd, and 5^th days by cutting the mandibular bone for histopathological examination, which was …

Costly Signaling Theory, Hui Ying Ivy Koh, Norman P. Li

Research Collection School of Social Sciences

Costly signaling theory is the idea that the high costs incurred by an individual to convey information about underlying qualities keeps this signal reliable, as only individuals who truly possess the quality signaled can afford to send the signal.

Precision And Efficacy Of Rna-Guided Dna Integration In High-Expressing Muscle Loci, Made Harumi Padmaswari, Gabrielle Bulliard, Shilpi Agrawal, Mary S. Jia, Sabin Khadgi, Kevin A. Murach, Christopher E. Nelson

Biomedical Engineering Faculty Publications and Presentations

Gene replacement therapies primarily rely on adeno-associated virus (AAV) vectors for transgene expression. However, episomal expression can decline over time due to vector loss or epigenetic silencing. CRISPR-based integration methods offer promise for long-term transgene insertion. While the development of transgene integration methods has made substantial progress, identifying optimal insertion loci remains challenging. Skeletal muscle is a promising tissue for gene replacement owing to low invasiveness of intramuscular injections, relative proportion of body mass, the multinucleated nature of muscle, and the potential for reduced adverse effects. Leveraging endogenous promoters in skeletal muscle, we evaluated two highly expressing loci using homology-independent …

Time Series Decomposition Of Land Surface Temperature For Long-Term Trend Forecasting And Impact On Nesting Sea Turtle Habitats In The Arabian Gulf, Sachi Perera, Rommel H. Maneja, Mohamed Allali, Cyril Rakovski, Erik Linstead, Daniele Struppa, Ali Qasem, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Improving land surface temperature (LST) modeling is vital for mitigating climate change effects on various ecosystems and marine habitats such as important sea turtle habitats. Over the past decade, extreme temperatures have likely significantly affected nesting sea turtle habitats in the Arabian Gulf, with predominantly female hatchlings creating an imbalance in the sex ratio. Such shifts have profound implications for these habitats’ long-term survival and conservation management. This study leverages statistical machine learning models to measure ongoing temporal variations in LST. We break down the LST time series into trend, seasonal, and noise components using classical decomposition methods like X11, …

Characterizing The Usda-Npgs Germplasm Collection Of Tartary Buckwheat (Fagopyrum Tataricum), Noah Joseph Abasciano

Master's Theses and Capstones

AbstractTartary buckwheat (Fagopyrum tataricum) is a promising underutilized crop in the context of New England’s rapidly changing environment (USDA NH State Profile, 2022). Despite substantive prior work on the genetics and nutrition of Tartary buckwheat (Zhang et al., 2017b), many practical questions pertaining to its potential cultivation in New England remain unanswered. This thesis presents the first systematic genotypic and phenotypic screening of the USDA National Plant Germplasm System's (NPGS) Tartary buckwheat germplasm collection in an effort to lay the foundations for future crop improvement efforts. The genotypic assessment of the NPGS Tartary buckwheat germplasm was completed by first bottlenecking …

Modeling Snow Surface Properties From Lidar And Imaging Spectroscopy, Brenton A. Wilder

Boise State University Theses and Dissertations

Seasonal snow surface plays an important role in altering terrestrial hydrology and global climate patterns. Snow reflects a majority of incoming shortwave radiation thereby reducing the net shortwave radiation received into snowpack throughout the season. This property is commonly referred to as snow albedo and impacts water cycles and air temperatures by modulating the timing and magnitude of melt. This reflectivity of snow is difficult to measure accurately in mountain environments and at a large enough scale to be meaningful for water resource managers and climate scientists. The work presented herein aims to improve methodologies to measure snow reflectivity from …

A Delphi Study Exploring Scope And Sequence Of Trauma Education In Counselor Education Master Level Council Of Accreditation Of Counseling Related Education Programs, Alexis A. Hauck

Dissertations

The growing awareness of trauma and its impacts on the social, emotional, and overall wellness of individuals, couples, and families underscores the need for counselor educators to prepare counselors to address trauma symptoms effectively. To bridge this gap, counselor education programs can benefit from expert guidance on the content scope and course sequencing of trauma education in master’s programs.

This research aimed to articulate trauma education scope and sequencing by gathering expert recommendations on best practices for trauma knowledge, awareness, and skill development through clinical experiences in counselor education programs. The grand research question explored expert opinions and beliefs about …

Ephemeral Legacy, Allison Hall

Master's Theses

Recently, my thoughts have centered on the problem of legacy. How do we forge bonds with other humans? What happens on an interpersonal level when these humans pass away, or when we pass, and they continue in life? How do queer spaces consistently offer deeper phenomena of interpersonal legacies; how does death operate as generational catalyst? I am particularly interested in putting these questions in the context of queer spaces. In queer culture, kinship is formed in ways that break from typical western notions of kinship. Despite being incoherent to western notions of family, queer bonds are extremely strong (Bradway …

Investigation Of Magnesium-Potassium Phosphates As Potential Nuclear Waste Form For The Immobilization Of Minor Actinides, Hans Conrad Zur Loye, Petr Vecernik, Monika Kiselova, Vlastislav Kašpar, Hana Korenkova, Vlastimil Miller, Petr Bezdicka, Jan Šubrt, Natalija Murafa, Volodymyr Shkuropatenko, Sergey Sayenko

Faculty Publications

Several recent studies have evaluated technologies of spent nuclear fuel processing specifically for solidifying transuranic (TRU) waste as a by-product of fission. Of the TRU group, plutonium and the minor actinides will be responsible for the bulk of the radiotoxicity and heat generation of spent nuclear fuel in the long term (300 to 20,000 years). In this study, we investigated magnesium potassium phosphate (MKP)-based compounds as host waste forms for the encapsulation of inactive trivalent Nd and Sm as analogues of the minor trivalent actinides, Am and Cm. Waste forms were fabricated under ambient atmospheric conditions by adding 5 wt.% …

Development, Characterization, And Application Of Nanomaterials For Target Detection And Therapeutic Study, Yingfen Wu

Theses and Dissertations

Nanomaterials have emerged as a pivotal area of research in chemistry, driven by their unique properties that make them suitable for both industrial and biomedical applications. Among nanomaterials, nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with the catalytic reactions of natural enzymes, conferring significant potential for their use in various biomedical applications. Herein, we describe three types of nanomaterials products with distinct properties and applications: 1) Fe³⁺-doped graphene quantum dots (GQDs) for sensitive H₂O₂ detection; 2) ratiometric fluorescent nanoprobes based on near-infrared (NIR) semiconducting polymer dots for label-free detection of dopamine; and 3) Multifunctional near …

Deep Learning Approach For Dental Anomalies X-Ray Imaging Using Yolov8, Amelia Ritahani Ismail, Md Salim Sadman Taseen

Knowledge Engineering and Data Science

Dental X-ray imaging is a critical diagnostic tool for identifying various dental anomalies. However, manual interpretation is time-consuming, prone to human error, and requires specialized expertise. Deep learning models, particularly object detection frameworks like YOLO, have demonstrated promising results in automating medical image analysis. This study aims to develop and evaluate a YOLOv8-based deep learning model for automated detection and classification of 14 dental anomaly categories, including Caries, Crowns, Fillings, Implants, and Periapical lesions. The proposed approach addresses limitations in previous YOLO versions by leveraging anchor-free detection and enhanced feature extraction for improved accuracy. The model was trained on a …

Occupational Performance With Formstack: Academic Fieldwork Coordinator's Perceptions And Experiences, Sara Clark

Dissertations

This multiple descriptive case-study explored the perceptions and experiences of eight occupational therapy program academic fieldwork coordinators (AFWCs), regarding their usage of Formstack, as an online fieldwork data collection system. Previous survey research revealed that AFWCs had positive feelings about the new AOTA Fieldwork Performance Evaluation (AOTA, 2020) housed within Formstack (Sanders & Carpenter, 2024), but the AOTA AFWC national list-serve suggests frustration with the online platform itself. Past research by Sanders and Carpenter (2024) also recommended further investigation into the usability of Formstack. To this end, this inquiry focused on two research questions: (a) How do AFWCs at multiple …

Integrated Transcriptomics And Proteomics Study Of Starvation Selected Drosophila Melanogaster, Aavash Adhikari

UNLV Theses, Dissertations, Professional Papers, and Capstones

Drosophila melanogaster, selected for starvation resistance exhibits phenotypic traits such as increased body size, slower development, reduced fecundity and obesity like characteristics including higher lipid reserves and cardiac dysfunction. While prior studies have explored the metabolic and biochemical changes in these flies, the underlying genetic and molecular mechanisms remain unclear. This study aims to investigate the gene expression and protein abundance in starvation-selected Drosophila through RNAseq, proteomics, and integrating both datasets using the MixOmics package in R. I found differential gene expression in the fat body at the third instar larval stage, particularly in pathways related to lipid metabolism, calcium …

Biological Reduction Of Mixed Oxyanions In Wastewater Brine, Katherine J. Earp

UNLV Theses, Dissertations, Professional Papers, and Capstones

Treatment of contaminated brine water is an area of active research spurred by the use of advanced treatment technologies, such as membrane separation, reverse osmosis, ion exchange, etc. for water reuse and recycling, which has become critical due to the impact of climate change on water resources throughout the globe. Biological reduction of harmful organic and inorganic pollutants in water has been demonstrated as an effective method for water and wastewater treatment and would be a potential technology for brine treatment. However, biodegradation of contaminants in high salinity waters is challenging because most microbial communities cannot survive brine environments. The …

Understanding Levels Of Perceived Racism And Discrimination When Utilizing Perinatal Care, Alexandria S. Evans

UNLV Theses, Dissertations, Professional Papers, and Capstones

Social and structural determinants of health, grounded in historical racism and discrimination, significantly influence maternal health outcomes. Because of this, communities of color experience a higher burden of maternal health disparities. In the last several decades, there has been an increased awareness of the need to integrate critical race theory into public health research to address maternal health disparities in the context of perinatal care delivery, policy, and funding decisions.

This three-manuscript dissertation utilized mixed methods to examine the ways in which systemic racism and discrimination are perceived and how it impacts the utilization of perinatal care services in historically …

Uptake Of Contaminants Of Emerging Concerns (Cecs) By Plants Irrigated With Recycled Waters, Abid Hussain

UNLV Theses, Dissertations, Professional Papers, and Capstones

The increasing demand for water in arid and semi-arid regions necessitates the use of recycled water (RW) for irrigation. RW is a viable alternative to conventional irrigation water at most locations, but it can be a major route for contaminants of emerging concerns (CECs) to be taken up by the tissues of food crops, thereby leading to their subsequent entry into the food chain. CECs include pharmaceuticals, personal care products, and industrial chemicals that are generally present at low concentrations in environmental waters, hence their common designation as trace organic compounds (TOrCs), and CECs also include microbiological constituents such as …

Physiology And Genomics At The Bottom Of The World: Genome To Phenome, Amy Christine Klink

UNLV Theses, Dissertations, Professional Papers, and Capstones

Mammals are exposed to a suite of physiological challenges based on the environment in which they inhabit. Animal individuals can overcome challenges associated with the dynamic nature of their habitat through variation in phenotypic traits. The plasticity of a phenotype relies on an individual’s genome and the transcription factors that act on regulatory elements. Species living in Antarctica display physiological specializations to withstand harsh conditions, such as severe cold temperatures, shifts in available ice habitat, and annual fluctuations in daylight. To explore the connections between an individual’s genome and its phenotype, we investigated two physiologies of the Antarctic Weddell seal …

Using Neighborhood Information To Improve Fiber Direction Estimation From Neuroimaging Data, Anjan Mandal

UNLV Theses, Dissertations, Professional Papers, and Capstones

Accurately estimating neuronal fiber directions is crucial in neuroimaging analysis. The Ball-and-Stick Model (BSM), introduced by Behrens et al. (2003), and widely used in software tools like FSL, remains one of the most popular models for this purpose. BSM analyzes each voxel individually, based solely on its signal information.In this dissertation, we propose modifications to BSM, that incorporate signal information from neighboring voxels in the estimation process, potentially improving the accuracy of the estimates. Additionally, within the estimation process, we introduce two novel proposal distributions to enhance the efficiency of the Markov chain Monte Carlo sampling procedure on the simplex …