Digital Commons Network^™

Dissemination And Implementation Of Injury Prevention Interventions: A Scoping Review For The Female, Woman And Girl Athlete Injury Prevention (Fair) Consensus, Brooke E. Patterson, Carly D. Mckay, Meghan L. Critchley, Destiny Lutz, Sallie M. Cowan, Nicholas Kolesky, Vanda White, Allison M. Ezzat, Andrew G. Ross, William M. Adams, Eva Ageberg, Clare L. Ardern, Marelise Badenhorst, Molly Coventry, Marc Olivier Dubé, Stacey Emmonds, Libby J. Gracias, K. Alix Hayden, Hanna Lindblom, Merete Møller, Christine Holm Moseid, Nancy Harrington, Dai Sugimoto, Evert Verhagen, Kate K. Yung, Phathokuhle C. Zondi

Research outputs 2022 to 2026

Objective: To synthesise evidence related to the dissemination and implementation (D&I) of injury prevention interventions for female, woman and/or girl (female/woman/girl) athletes. Design Scoping review. Data sources MEDLINE, APA PsycInfo, Cochrane Databases for Systematic Review, Cochrane Central Register for Controlled Trials Registry, EMBASE, CINAHL, SPORTDiscus, ERIC, ProQuest Dissertation and Theses Global. Eligibility Primary research including ≥25% female/woman/girl athletes of any age or people working with them (eg, coaches), participating in sports competition and/or performance, were eligible. Papers reporting D&I outcomes (eg, coach knowledge, adoption and maintenance) related to an injury prevention intervention and/or a factor (eg, coach beliefs) associated with …

Of Scents And Cytokines: How Olfactory And Food Aversions Relate To Nausea And Immunomodulation In Early Pregnancy, Dayoon Kwon, Daniel M.T. Fessler, Delaney A. Knorr, Kyle S. Wiley, Julie Sartori, David A. Coall, Molly M. Fox

Research outputs 2022 to 2026

Background: During pregnancy, the maternal body undergoes extensive physiological adaptations to support embryonic growth, including whole-body remodeling, that may induce odor and food aversions, as well as nausea and vomiting. The biological mechanisms behind odor and food aversions, as well as nausea and vomiting in early pregnancy, remain largely unexplored. Our study investigated associations between these changes and cytokine profiles during pregnancy. Methodology: A cohort of pregnant Latina women in Southern California (n = 58) completed a structured questionnaire on pregnancy "morning sickness"-related symptoms and aversions. Maternal plasma cytokine levels were measured between 5 and 17 weeks' gestation. Results: About …

Prognostic Value Of Neutrophil-To-Lymphocyte Ratio, Platelet-To-Lymphocyte Ratio, And Lactate Dehydrogenase Level In Melanoma Patients Treated With Immune Checkpoint Inhibitors, Wynne Wijaya, Muhammad Adnan Khattak, Afaf Abed, Tarek Meniawy, Michael Millward, Elin Gray, Oliver Oey

Research outputs 2022 to 2026

Introduction: Metastatic melanoma carries a poor prognosis. Immune checkpoint inhibitors (ICIs) have improved outcomes, but responses remain variable, highlighting the need for simple prognostic biomarkers. Inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lactate dehydrogenase (LDH) reflect tumour burden and inflammation, though their clinical utility is unstandardised. Methods: We retrospectively analysed 103 metastatic melanoma patients treated with anti-PD-1 monotherapy at two centres in Western Australia (2014–2020). Baseline NLR, PLR, and LDH were assessed within 30 days pre-treatment. Outcomes included clinical benefit, progression-free survival (PFS), and overall survival (OS). Results: Poor ECOG performance status (PS ≥2) (RR 2.39, …

Risky Topics In Health Education: Enacted Content When Students With Migration Backgrounds Meet Swedish Health Education, Mikael Quennerstedt, Annica Caldeborg, Dean Barker, Valeria Varea

Research outputs 2022 to 2026

School health educational content often entails different subject areas and a variety of topics that students are supposed to learn, and when taught in diverse classrooms, potentially positions students as at-risk. Using vignettes in interviews with migrant students in Sweden, the study focuses on views of the content of health education in relation to different ways that health as risk is enacted. Four aspects of risk were identified: (i) risk as content in health education and risky, including topics such as nutrition, stress, smoking, and pollution; (ii) risk as content in health education but not so risky, including topics such …

The Affective Milieu Of School Market Competition: Using Affect And Governmentality To Study Market Competition, Brad Gobby, Amanda Keddie, Jill Blackmore, Katrina Macdonald

Research outputs 2022 to 2026

This paper integrates insights from affect theory into Foucault’s governmentality framework to analyse school markets. Using a Deleuzian approach to affect, we theorise school markets as an affective milieu that composes the field of competition. Drawing on interviews with staff at two rival high schools, we highlight how an affective milieu that included threat, anxiety, insecurity, resentment and confidence shaped market dynamics. Our analysis shows that affective milieus reflect and reinforce power asymmetries in local school markets and are a condition for generating competitive practices to enhance schools’ capacities to affect and be affected. Our central point is to move …

Tying The Goreum: Using Stanislavsky’S Concept Of Emotional Memory To Capture A Childhood, Susie Conte

Research outputs 2022 to 2026

Goreum/Ties was a cross-cultural, multidisciplinary theatre project that explored memory, identity, and belonging. Developed during a residency at Incheon Art Platform in collaboration with Fremantle Arts Centre, the work marked my first return to Korea in 35 years. This journey allowed me to reconnect with my ten-year-old self and reassemble the fragments of memory into performance. Blending theatre, video, sound, and fabric as transformative media, the project engaged audiences in a tapestry of cultural perspectives that shape remembrance. I drew on Stanislavski’s concept of emotional memory to filter my childhood in South Korea into poetic reflection. My experiences as a …

3d Engineered Scaffolds Of Conjugated Polymers/Metal Organic Frameworks For Biomedical Applications, Amin Hosseini Sharifabad, Roham Ghanbari, Mohammad Reza Saeb, Ehsan Nazarzadeh Zare, Filippo Rossi, Mehdi Salami-Kalajahi, Pooyan Makvandi

Research outputs 2022 to 2026

The extracellular matrix can be replicated by 3D scaffolds, providing a favorable environment for cell growth, proliferation, and differentiation. Despite their biocompatibility, biodegradability, and bioactivity, the poor mechanical strength of 3D scaffolds limits their use for heavy loads. This creates a bottleneck in the supply of scaffolds with enhanced mechanical strength and all the previously mentioned characteristics. Conjugated polymers have emerged as a promising option for 3D scaffold construction due to their electrical conductivity, adjustable surface qualities, and ability to transfer bioactive molecules. Moreover, metal-organic frameworks (MOFs) are a rapidly emerging class of nanomaterials due to their uniform porosity, excellent …

Blurred Vision: Understanding Barriers To Initiating Collaborative Market Driving, Kim Feddema, Daniel Schepis, Liudmila Tarabashkina, Sharon Purchase

Research outputs 2022 to 2026

Purpose: This paper aims to examine why many producers of origin-bound products struggle to collectively drive increases in market value, despite shared interests. The authors apply a collaborative market driving (CMD) lens to the early stages of collective efforts, to identify the key motivators, visioning processes and explore why CMD can fail to initiate. Design/methodology/approach: The authors present a qualitative case study of the Western Australian monofloral honey industry. Data includes 64 producers’ and distributors’ online content and 30 interviews with stakeholders. Leximancer was used to map marketing communications, and participant narratives were thematically analysed using terroir and authenticity frameworks. …

Enhancing Cardiovascular Risk Prediction In Hypertensive Adults: A 3pm-Based Evaluation Of Insulin Resistance And Arterial Stiffness, Yulong Lan, Zhaogui Wu, Dan Wu, Lingyu Xu, Hongfa Wei, Chutao Wu, Youren Chen, Xiaolan Li, Shouling Wu

Research outputs 2022 to 2026

Objective: Hypertension management remains challenging due to coexisting insulin resistance (IR) and arterial stiffness—two silent yet synergistic drivers of atherosclerotic cardiovascular disease (ASCVD). This study aimed to evaluate their joint impact on ASCVD risk and assess their utility in predictive, preventive, and personalized strategies. Methods: In this prospective cohort study of 30,094 adults with hypertension, IR was assessed using the triglyceride-glucose (TyG) index (calculated as ln [TG (mg/dL) × FBG (mg/dL)/2]) and arterial stiffness via brachial-ankle pulse wave velocity (baPWV). Time-to-event analyses examined their individual and combined associations with ASCVD incidence. Results: Over a median 5.6-year follow-up, 1655 ASCVD cases …

Intake Of Total, Classes, And Subclasses Of (Poly)Phenols And Risk Of Lymphoid Neoplasms: A Prospective Analysis In The Epic Cohort, Enrique Almanza-Aguilera, David Guananga-Álvarez, Yolanda Benavente, Alexandra Nieters, Caroline Besson, Fatemeh Saberi Hosnijeh, Cecilie Kyrø, Nicola P. Bondonno, Christina C. Dahm, Elisabete Weiderpass, Therese Truong, Mariem Louati-Hajji, Xuan Ren, Verena Katzke, Matthias B. Schulze, Fabrizio Pasanisi, Claudia Vener, Giovanna Masala, Maria Teresa Giraudo, Rosario Tumino, Amaia Aizpurua, Maria Jose Sánchez, José María Huerta, Marcela Guevara, Cristina Lasheras, Paolo Vineis

Research outputs 2022 to 2026

Background: Existing epidemiological evidence regarding the potential role of (poly)phenol intake in lymphoma development is limited. Methods: We investigated the associations between the intake of total and individual classes and subclasses of (poly)phenols and the risk of lymphoma, including main frequent subtypes in the EPIC cohort using multivariable-adjusted Cox proportional hazards models. Results: During a mean 14-year follow-up (time frame: from 1990–1994 to 2008–2013), 2394 incident lymphoma cases were diagnosed from a total of 367,463 individuals. No significant associations were observed between total intakes of (poly)phenols, flavonoids, and phenolic acids and overall lymphoma risk. Total (poly)phenols, phenolic acid and hydroxycinnamic …

Evaluating Communication And Clinical Skills In Objective Structured Clinical Examination (Osce) Using A Low-Cost Neck-Mounted Device, Insights From A First-Person Perspective, Chao-An Chen, Yu Ching Liu, I-Ching Liao, Ching-Yi Wu, Chung-Han Ho, Chih-Hao Lu, Kuan-Liang Chen

Journal of Dental Sciences

Abstract Background/purpose This study used a neck-mounted mobile phone from a first-person perspective to record the performance of dental interns in an objective structured clinical examination (OSCE) to evaluate the effectiveness of video feedback and to assess medical communication and clinical skills. Materials and methods Standardized patients wore neck-mounted mobile phones to record the examination process from a first-person perspective (FPP). Pre- and post-test questionnaires measuring anxiety, impacts on communication skills and performance, distraction, technical challenges, feedback received from video, and educational value of the neck-mounted phones were completed by dental interns. The questionnaires were scored on a four-point scale …

Methyl-Cpg-Binding Domain As A Protein Interaction Partner In Promoter Regulation And Neurodevelopment Through Evolutionary Expanded Entanglement, Stephanie M. Bilinovich, Surya B. Chhetri, Jackson T. Mitchell, Gage O. Leighton, Vladislav Jdanov, Jacob K. Zieba, Taylor W. Cook, Krysta L. Engel, Robert M. Vaughan, Humza Bhatti, Sadie L. Heeringa, Amy M. Wilstermann, Sophie Vanderweele, Akansha S. Das, Emily C. Sherry, Stephen A. Duncan, Katie L. Uhl, David C. Hinds, Mark Mackiewicz, Sarah K. Meadows, Kimberly M. Newberry, E. Christopher Partridge, Sara G. Cline, C. Joy Shepard, D. Casey Smith, Antonio Bradley, Daniel Vogt, Daniel B. Campbell, Lucas Pozzo-Miller, Caleb P. Bupp, Austin J. Goodyke, Surender Rajasekaran, Rebecca C. Knickmeyer, Benjie Blair

Research, Publications & Creative Work

There is increasing evidence that the methyl-binding domain (MBD) is a protein-protein interaction motif that can function independently of methylated DNA binding. The MBD proteins found throughout plants and invertebrates duplicated into multiple vertebrate DNA and non-DNA-binding members (MBD1, MBD2, MBD3, MBD4, MBD5, MBD6, MECP2, BAZ2A, BAZ2B, SETDB1, andSETDB2). Although many invertebrate species possess MBD proteins that can bind and recognize DNA methylation, the DNA-binding function has been independently lost multiple times, with only minor alterations to the protein interaction residues. The nucleosome remodeling and deacetylase (NuRD) complex, which interacts with MBD2/3 and is colocalized with MBD1/4 ChIP-Seq, is maintained …

Delayed Tooth Eruption As An Early Clinical Indicator Of Genetical Tooth Agenesis: A Family-Based Study Of Cases With Whole-Exome Sequencing, Yu-Chen Jeng, I-Ting Chen, Hui-Ching Cheng, Hsin-Yu Huang, Chao-Kai Hsu, Yu-Fen Yen

Journal of Dental Sciences

Delayed tooth eruption is frequently considered a benign developmental variation but may represent an early sign of genetically driven tooth agenesis. We evaluated a 22-month-old female presenting with markedly delayed eruption (only eight primary teeth) and a positive family history of ectodermal features. Given the inconclusive early radiographic findings, whole-exome sequencing (WES) was utilized. WES revealed the proband carried a heterozygous EDARADD variant (NM_080738:c.328G>T; p.Asp110Tyr). Subsequent familial segregation analysis identified an additional heterozygous WNT10A variant (NM_025216:c.637G>A; p.Gly213Ser) within the broader family. The EDARADD variant alone was associated with varying presentations from normal dentition to delayed eruption. Furthermore, the …

The Lived Experiences Of African American Women In Predominantly White Higher Education Institutions In Texas And Their Journey To Advancement To Tenure, Wanda Yvonne Carter-Dyer

Electronic Theses and Dissertations

Abstract

African American women are underrepresented in predominantly White higher education institutions in Texas. Inconsistent treatment and policies have contributed to the disparate numbers of African American women in predominately White institutions. African American women are subjected to discrimination based on race, sex, and color. The problem investigated in this study was the barriers to African American tenure-seeking women in predominately White institutions. Barriers discussed in those interviews were discrimination, equity, inclusion, lack of support systems, organizational culture and relationships, and mentors. Six African American women in PWIs in Texas were interviewed to give a voice to the barriers experienced …

Urban Heat Island Effects On Arthropod Populations And Communities In Jacksonville, Fl, Eleanor G. Cronin

UNF Graduate Theses and Dissertations

The urban heat island (UHI) effect makes urban areas hotter than rural areas. Urban areas, and the extreme heat that comes with them, are becoming more common worldwide. If UHIs lead to changes in arthropod community diversity, then ecosystem structure and services could be disrupted. Previous UHI studies have investigated heat impacts on arthropod ecology, but many focus on one species while studies that consider thermal diversity within a single urban area have been limited. In Jacksonville, Florida, areas that are 12°C hotter than the coolest areas are considered local UHIs. The goal of this research is to investigate how …

Diversity Makes Me Uncomfortable: Effects Of Diversity Language On University Student Belonging, Ziena Baker

UNF Graduate Theses and Dissertations

Diversity statements and experiences form the first impressions students have of their prospective universities and employers, setting the stage for perceived feelings of belonging, otherness, and comfort within new environments (Baleria, 2021; O’Keeffe, 2013; Starck et al., 2021). Diversity statements can signal feelings of comfort and belonging or feelings of stress depending on the way in which diversity is framed (Chaney, 2022; Trawalter et al., 2016). This is especially true for students, who are more often affected mentally and physically by changes in university diversity perspectives (Sladek et al., 2021) The current study thus uses a novel blood pressure measure …

Interpreting Topic Models In Byte-Pair Encoding Space, Jia Peng Lim, Hady Wirawan Lauw

Research Collection School Of Computing and Information Systems

Byte-pair encoding (BPE) is pivotal for processing text into chunksize tokens, particularly in Large Language Model (LLM). From a topic modeling perspective, as these chunksize tokens might be mere parts of valid words, evaluating and interpreting these tokens for coherence is challenging. Most, if not all, of coherence evaluation measures are incompatible as they benchmark using valid words. We propose to interpret the recovery of valid words from these tokens as a ranking problem and present a model-agnostic and training-free recovery approach from the topic-token distribution onto a selected vocabulary space, following which we could apply existing evaluation measures. Results …

How Can Tailored Entrepreneurship Training Effectively Support The Emancipation Of People With Disabilities In Ireland?, Ahsan Habib

Doctoral

This thesis investigates the impact of tailored entrepreneurship training on the perceived emancipation of aspiring entrepreneurs with disabilities in Ireland. This community is significantly underrepresented in the labour market, yet it is hindered in accessing self-employment opportunities due to a lack of specific training and limited access to necessary resources. Furthermore, there is a dearth of knowledge in academic literature addressing the influence of tailored entrepreneurship programmes targeted at people with disabilities. To address this knowledge gap, this study gathered data from in-depth interviews with 21 key informants (including nine participants from TU Dublin’s entrepreneurship training programme, five representatives from …

Adversarial Generative Flow Network For Solving Vehicle Routing Problems, Ni Zhang, Jingfeng Yang, Zhiguang Cao, Xu Chi

Research Collection School Of Computing and Information Systems

Recent research into solving vehicle routing problems (VRPs) has gained significant traction, particularly through the application of deep (reinforcement) learning for end-to-end solution construction. However, many current construction-based neural solvers predominantly utilize Transformer architectures, which can face scalability challenges and struggle to produce diverse solutions. To address these limitations, we introduce a novel framework beyond Transformer-based approaches, i.e., Adversarial Generative Flow Networks (AGFN). This framework integrates the generative flow network (GFlowNet)-a probabilistic model inherently adept at generating diverse solutions (routes)-with a complementary model for discriminating (or evaluating) the solutions. These models are trained alternately in an adversarial manner to improve …

Sex Differences In Prognostic Factors And Genomic Variations In Oral Squamous Cell Carcinoma: A 5-Year Retrospective Study, Shih-Jung Cheng, Hui-Hsin Ko, Fang-Yu Wu, Ya-Syan Chen, Wender Lin, Chun-Kai Fang, Chyi-Huey Bai, Hung-Ying Lin, Hsiang-Fong Kao

Journal of Dental Sciences

Abstract Background/purpose This study examined the prognostic factors and genomic variations in oral squamous cell carcinoma (OSCC) among male and female patients, focusing on the rising incidence of OSCC in women. Materials and methods Using data from 98 OSCC cases treated at National Taiwan University Hospital between 2013 and 2018, the study analyzed the patient cohort, clinical characteristics, and genomic profiles. Results The Female patients had a higher incidence of tongue cancer, while the male patients were prone to have buccal cancer. Key prognostic factors included age over 55 years, tongue cancer, alcohol use in female patients as well as …

Mechanical And Biological Properties Of Cellulose Nanofibers As A Dental Biomaterial, Guang Hong, Junduo Chen, Aobo Ma, Yiding Zhang, Lu Sun, Kunhua Yang, Juan Ramón Vanegas Sáenz

Journal of Dental Sciences

Abstract Background/purpose Plant-derived cellulose nanofibers (CNF) have emerged as a promising material for biomedical applications due to their diverse and exceptional properties but application in dental research remains limited. This study aimed to use CNF as barrier membranes or scaffold materials applied in guided bone regeneration (GBR) and guided tissue regeneration (GTR). Materials and methods Two different thicknesses of CNF were detected by surface morphology, roughness, hydrophilicity, mechanical properties, and degradability test, and compared with GC Membrane and Ti (titanium). Additionally, the cell compatibility and cell morphology of MC3T3-E1 and HGF-1 in different groups were also studied. The alkaline phosphatase …

Multiple Implant Placements With Simultaneous Soft Tissue Augmentation Using A Volume-Stable Collagen Matrix Compared To Autogenous Connective Tissue Graft: A Clinical And Histological Pilot Study, Jamil Boulos, Abdel-Rahman Kassir, Gabriel Menassa, Nada Naaman

International Arab Journal of Dentistry

Introduction: The use of soft tissue grafts has been a key component in periodontal and implant surgeries for the past five decades, aiming to increase the width of keratinized tissue and soft tissue volume.

Objectives: This study evaluates the efficacy of a three-dimensional volume-stable collagen matrix (VCMX) compared to subepithelial connective tissue grafts (SCTG) in increasing soft tissue thickness and volume during multiple implant placements.

Methods: A randomized controlled clinical trial was conducted with four patients and eight implants. Patients were allocated to the SCTG or VCMX group, with soft tissue augmentation performed simultaneously with implant placement. …

Continuous Monitoring Of Sterility: Bacterial Contamination And Disinfectant Performance In Dental Clinics, Nathaly Alsalloum, Tarek Aboajwa, Shuaib Alahmad, Nermin Almouhammad

International Arab Journal of Dentistry

Objectives: This study aimed to (1) evaluate contamination levels across three clinics (endodontic, extraction and surgery, and fixed prosthodontics), (2) identify the types and prevalence of bacteria, (3) estimate the effectiveness of a commercial disinfectant, and (4) determine the bacterial species most responsive to the disinfectant.

Methods: Equal surfaces (17.98 cm²) were swabbed, cultured on nutrient agar for the total aerobic microbial count before and after disinfection, and analyzed using settle plates. Bacterial identification was conducted through colony characteristics, Gram staining, and biochemical tests. Data were processed using SPSS version 26.

Results: The endodontic clinic exhibited …

Evaluation Of Microtensile Bond Strength Of Composite Under Three Aging Conditions: A Comparative In Vitro Study, Fadi Hammoud, Louis Hardan, Maryse Nassif, Tala El Ghoul, Georges Najjar, Cynthia Kassis

International Arab Journal of Dentistry

Objectives: To investigate the effects of different in-vitro artificial aging protocols on the micro tensile bond strength (µTBS) of composite restorations applied to dentin.

Methods: A total of 88 teeth were prepared on dentin and divided into three distinct aging conditions and a control group : G1) Control group with no aging (n=22); G2) Thermal Cycling (Thermocycling) involving 10,000 cycles between 5°C and 55°C, with a dwell time of 20 seconds (n=22); G3) Mechanical Loading (Cyclic loading) with a 50 N load, a frequency of 1.5 Hz, and 10,000 cycles (n=22); G4) Combined Thermo-mechanical cyclic loading (TMCL) using …

Oral Lesion As The Initial Presentation In The Diagnosis Of Histiocytosis X: A Case Report With 16-Month Follow-Up, Wassim Al Manhal, Georgio Saad, Charbel Anka, Valerie Aftimos, Michael Daccache, Sophie Abi Raad, Georges Boujaoude

International Arab Journal of Dentistry

Introduction: Langerhans Cell Histiocytosis (LCH) is a rare neoplastic disease that comes from the abnormal proliferation of Langerhans cells (LCs). It presents with a broad clinical spectrum, varying from involvement of a single organ system to multisystem disease, and frequently affects children, although cases in adults have been reported. Oral manifestations of LCH are non-specific and may mimic common periodontal conditions, posing a diagnostic challenge for dental practitioners.

Case Presentation: A 63-year-old female patient presented with complaints of periodontal problems. She was initially diagnosed with periodontitis, but symptoms persisted despite treatment, prompting a referral for further evaluation. Histopathological …

The Association Of Hyperhomocysteinemia (Hhcy) With Cancer Risk: An Updated Systematic Review And Meta-Analysis Of Case-Control Studies (2013-2024), Hajar Heidari

Electronic Theses & Dissertations (2024 - present)

Abstract:

Cancer continues to be one of the leading causes of morbidity and mortality globally, influenced by a complex interplay of genetic, environmental, and nutritional factors. Among these, the metabolism of homocysteine (HCY), a sulfur-containing amino acid derived from dietary methionine, has attracted growing attention due to its involvement in one-carbon metabolism and its potential link to cancer. Elevated HCY levels, a condition known as hyperhomocysteinemia (HHCY), have been shown to disrupt crucial cellular processes such as DNA methylation and promote oxidative stress (OS)—both of which contribute to genomic instability and cancer progression. Disruptions in the folate and methionine cycles, …

Diversity, Genomics And Antimicrobial Resistance Of Coagulase-Negative Staphylococcus: A Literature Review, Kathleen Okeefe

Electronic Theses & Dissertations (2024 - present)

Members of the gram-positive bacterial genus Staphylococcus have historically been classified into coagulase-positive Staphylococcus (CoPS) and coagulase-negative Staphylococcus (CoNS). This classification is based on the ability of clotting of plasma by the coagulase enzyme, which converts fibrinogen to fibrin. CoNS species are ubiquitous commensals that frequently colonize the skin and mucosal surfaces. They are also opportunistic pathogens implicated in many human and animal infections. The evolutionary history of CoNS has generally been overlooked because of the historical lack of recognition for their clinical importance and poor taxonomic sampling. They are often perceived as being less or non-pathogenic, especially compared to …

Resources To Study The Isoforms Of The P53 Family Of Transcription Factors, Dana L. Woodstock

Electronic Theses & Dissertations (2024 - present)

The p53 family of transcription factors regulates diverse gene regulatory networks such as those involved in DNA damage repair, epidermal commitment, and neuronal development. As a result, dysfunction in these pathways lead to numerous human health conditions, including multiple types of cancer and craniofacial developmental disorders. Each family member regulates a distinct gene network leading to varied cellular and organismal phenotypes, but all are capable of regulating programmed cell death, likely due to considerable similarity between protein structure and binding sites in DNA. Analysis of these shared and distinct functions is complicated by each p53 family member gene (TP53, TP63, …

The Dynamics Of Mystical Experiences: Interaction Effects And Distinct Contributions Of Meq-30 Factors, Genevieve Falabella

Electronic Theses & Dissertations (2024 - present)

Many participants in clinical trials of psychedelic-assisted therapy (PAT) report mystical experiences. Researchers often use the 30-item Mystical Experience Questionnaire (MEQ-30) to measure mystical experiences. Several studies have validated a four-factor structure of the MEQ-30, but only as a subset of items within broader versions of the scale (e.g., MEQ-43). As such, the factor structure of the standalone MEQ-30 remains unvalidated in English. Additionally, some data suggest that certain factors might be more strongly associated with psychedelic-associated outcomes than others, which could provide insight to enhance the therapeutic potential of PAT. The aim of this study was to examine the …

A Theoretical And Empirical Adaptation Of Signaling Theory For Digital Communication: Examining Organizational Brand Identity And Credibility, Victoria Barbeisch

Electronic Theses & Dissertations (2024 - present)

This dissertation adapts signaling theory for digital communication and tests its relevance in strategic communication, specifically concerning unobservable organizational traits like brand identity values. Signaling theory explains how parties with unequal information (senders/signalers and receivers) use signals to bridge knowledge gaps and influence decision-making. While rooted in biology and economics, its application in computer-mediated communication (CMC) remains limited. This research addresses this gap through two primary aims. Aim 1 presents the first comprehensive theoretical adaptation of signaling theory for digital communication, consolidating fragmented research across multiple disciplines. Aim 2 investigates the theory's relevance in strategic communication related to unobservable brand …