Effects Of Dietary L-Tryptophan On Growth Performance, Feed Utilization, And Protein Metabolism In Nile Tilapia (Oreochromis Niloticus), Israt Mishu, Lindee Mason, Ahmed Mustafa

Mansoura Veterinary Medical Journal

This research examines the impact of dietary L-tryptophan supplementation on growth performance, feed efficiency, and protein metabolism in Nile tilapia (Oreochromis niloticus) under stress and non-stress settings. This experiment evaluated essential growth metrics, encompassing weight gain, length gain, specific growth rate, feed conversion ratio, and protein energy retention. Nile tilapia were categorized into four experimental groups: a control group on a commercial diet, a control group supplemented with L-tryptophan (0.33%/kg feed), a stress-induced group receiving cortisol (0.02%/kg feed), and a stress-induced group receiving both cortisol (0.02%/kg feed) and L-tryptophan supplementation (0.33%/kg feed). The findings indicated that Ltryptophan supplementation significantly enhanced …

Securing The Internet Of Wetland Things (Iowt) Using Machine And Deep Learning Methods: A Survey, Guma Ali, Wamusi Robert, Maad M. Mijwil, Malik Sallam, Jenan Ayad

Mesopotamian Journal of Computer Science

Wetlands are essential ecosystems that provide ecological, hydrological, and economic benefits. However, human activities and climate change are degrading their health and jeopardizing their long-term sustainability. To address these challenges, the Internet of Wetland Things (IoWT) has emerged as an innovative framework integrating advanced sensing, data collection, and communication technologies to monitor and manage wetland ecosystems. Despite its potential, the IoWT faces substantial security and privacy risks, compromising its effectiveness and hindering adoption. This survey explores integrating machine learning (ML) and deep learning (DL) techniques as solutions to address the security threats, vulnerabilities, and challenges inherent in IoWT ecosystems. The …

Retinal Vessel Image Segmentation Based On Guided Filter And Neural Networks, Ibrahem Al-Jadir, Jawad S. Hameed, Husam Yahya, Dalia N. Al-Oboudi

Mesopotamian Journal of Artificial Intelligence in Healthcare

Accurate segmentation of retinal blood vessels is essential for the early diagnosis and monitoring of various ophthalmic and systemic diseases. This work shows how to use a modified U-Net architecture to improve how retinal blood vessels are segmented. The method uses rolling guidance filters with two different sets of parameters to make the edges of the vessels sharper and make it easier to tell them apart. Separate U-Net models process each filtered image independently, and then the outputs are combined to make the final segmentation result. Both networks are trained at the same time using a shared loss function. Tests …

Kafka In The Plague Years: Reinterpreting Absurdity In The 2020s, Chris Lownie

Electronic Theses & Dissertations (2024 - present)

No word better encapsulates the confusion and inequality proliferating in the post-2020 global world than “absurd.” Absurdity consumes the way we interact with one another, going about life-as-usual in pocket worlds in which the individual is alienated from both oneself and others. Life is defined by a series of problems that regularly go ignored by both institution and general populace alike, but not by the human body: the effects of sustained illness and reinfection by recurrent viruses in a world that no longer acknowledges their severity nor their pervasiveness nor steps we may take towards personal safety. Daily life has …

Effects Of Formative Assessment On Students’ Regulation Of Learning: A Meta-Analysis, Ching-Yen Yu

Electronic Theses & Dissertations (2024 - present)

Does formative assessment (FA) promote self-regulated learning (SRL)? Theoretically, FA has long been believed to facilitate SRL due to their overlapping conceptual frameworks, yet empirical evidence has remained scattered and inconclusive. This study presents the first comprehensive, large-scale meta-analysis to examine whether, to what extent, for whom, and under what conditions FA enhances SRL.

Following a preregistered, PRISMA-guided protocol, we systematically searched the literature from 1998 to 2024 and synthesized 999 effect sizes from 138 studies (n = 23,293 students) using multilevel meta-analytic models that accounted for dependent effects. Across educational levels and contexts, FA, on average, demonstrated a …

Sulfur Chemistry For Protein Synthesis And Modification: From Thiolactone To Bicyclic Sulfoxide Frameworks, Yuming Wen

Electronic Theses & Dissertations (2024 - present)

This dissertation explores two intersecting themes in modern chemical biology: (1) the design of novel ligands for transition-metal catalysis, and (2) the development of thiolactone-mediated strategies for protein synthesis and modification in aqueous media. Together, these studies advance chemical methods for precise molecular transformations under mild, biocompatible conditions.

In the first chapter, a geometrically constrained bicyclic [3.3.1] sulfoxide framework was developed as a new class of bissulfoxide ligands for palladium-catalyzed C–H functionalization. The ligand was synthesized concisely from thiophenol through a three-step sequence and shown to promote allylic C–H amination and alkylation reactions with high efficiency. The catalytic system tolerated …

A Study Of Glyphosate, Pesticide Mixtures, And Metabolic Health Outcomes: Integrating Epidemiologic, Mechanistic, And Ecological Evidence On Environmental Drivers Of Metabolic Health, Sarah Otaru

Electronic Theses & Dissertations (2024 - present)

Glyphosate, the most extensively used herbicide worldwide, has become a ubiquitous environmental contaminant. Although initially considered safe due to its specific biochemical target in plants, emerging evidence suggests that chronic, low-level human exposure may disrupt metabolic processes. Simultaneously, the global rise in metabolic disorders such as metabolic syndrome (MetS), obesity, and type 2 diabetes, has created a pressing need to identify novel, potentially modifiable environmental contributors. This dissertation investigates the relationship between glyphosate and metabolic health through a triangulated framework that integrates individual-level epidemiological analysis, systematic synthesis of mechanistic evidence, and ecological evaluation of pesticide mixtures.

The first study employed …

Diversity, Genomics And Antimicrobial Resistance Of Coagulase-Negative Staphylococcus: A Literature Review, Kathleen Okeefe

Electronic Theses & Dissertations (2024 - present)

Members of the gram-positive bacterial genus Staphylococcus have historically been classified into coagulase-positive Staphylococcus (CoPS) and coagulase-negative Staphylococcus (CoNS). This classification is based on the ability of clotting of plasma by the coagulase enzyme, which converts fibrinogen to fibrin. CoNS species are ubiquitous commensals that frequently colonize the skin and mucosal surfaces. They are also opportunistic pathogens implicated in many human and animal infections. The evolutionary history of CoNS has generally been overlooked because of the historical lack of recognition for their clinical importance and poor taxonomic sampling. They are often perceived as being less or non-pathogenic, especially compared to …

Technological Development Of In-Cell Nmr: Microfluidic, Metabolomic, And Fluxomic Approaches, Nicholas Sciolino

Electronic Theses & Dissertations (2024 - present)

In the fields of structural biology, metabolomics, and fluxomics, there is a driving, technique-based concern when it comes to high-resolution spectrometry and its marriage to biological and physiological relevance. Sample preparation often involves cellular perturbation, lysate separation schemes, combinations with non-biological reagents, and timeline slack. Conceptually, the farther we get from the cell, the greater the potential disparity between what exists in vivo and our in vitro manipulations. This is particularly true when seeking to collect data on transfected targets of interest, and on sensitive metabolic equilibria that occur on the order of minutes. The question remains: if we are …

A Theoretical And Empirical Adaptation Of Signaling Theory For Digital Communication: Examining Organizational Brand Identity And Credibility, Victoria Barbeisch

Electronic Theses & Dissertations (2024 - present)

This dissertation adapts signaling theory for digital communication and tests its relevance in strategic communication, specifically concerning unobservable organizational traits like brand identity values. Signaling theory explains how parties with unequal information (senders/signalers and receivers) use signals to bridge knowledge gaps and influence decision-making. While rooted in biology and economics, its application in computer-mediated communication (CMC) remains limited. This research addresses this gap through two primary aims. Aim 1 presents the first comprehensive theoretical adaptation of signaling theory for digital communication, consolidating fragmented research across multiple disciplines. Aim 2 investigates the theory's relevance in strategic communication related to unobservable brand …

Assessing Antiretroviral Therapy Prescribing Practices In New York State For Pregnant People Living With Hiv, Beverly Amofah

Electronic Theses & Dissertations (2024 - present)

ABSTRACT

Objective: The Panel on Treatment of HIV During Pregnancy and Prevention of Perinatal Transmission advises patient counseling to facilitate informed decision-making when evaluating changes in antiretroviral therapy (ART) during pregnancy and for patients to stay on suppressive regimens regardless of drug class. The purpose of this study was to investigate racial and ethnic disparities in the prescription of ‘preferred’ HIV drug regimens for pregnant people living with diagnosed HIV in New York State (NYS). This research also assessed whether prescribing practices for pregnant people on ART were consistent with Department of Health and Human Services (DHHS) guidelines.

Methods: A …

Adaptive Evolution Shapes The Transmissibility Of West Nile Virus In New York State, Sean M. Bialosuknia

Electronic Theses & Dissertations (2024 - present)

Arthropod-borne viruses (arboviruses), which are maintained in nature in complex transmission cycles involving hematophagic invertebrates and their vertebrate hosts, are the cause of a significant and expanding global health burden. Defining arbovirus-host interactions is necessary if we are to understand the adaptive and epidemiological potential of arboviruses. The results presented with West Nile virus (WNV Flaviviridae: Orthoflavivirus), are a compilation of such studies. WNV is the most prevalent arboviral pathogen in the U.S. and the most geographically distributed arbovirus in the world. Despite the evolutionary potential of these RNA viruses, WNV and other arboviruses have experienced only limited …

Diversity Within Species: Mechanisms, Evolution And Implications In Bacterial Disease, Kathryn R. Piper

Electronic Theses & Dissertations (2024 - present)

The Gram-positive bacterium Staphylococcus aureus and the Gram-negative bacterium Escherichia coli are ubiquitous commensal and opportunistic pathogens. In humans, S. aureus is commonly found on the skin and mucus membranes, and is known to cause infections in the skin, bloodstream and brain. E. coli is a normal part of the gut microbiota in humans and can cause intestinal and extraintestinal infections alike. S. aureus and E. coli pose global threats to public health, due to the high morbidity and mortality of invasive strains. The wide range of infections they cause in humans and other animals are exacerbated by the presence …

Light-Driven Chemistry: Photoswitch In Rna Activity Control And Development Of Photoredox Catalysis, Juncheng Li

Electronic Theses & Dissertations (2024 - present)

This dissertation is structured into two principal segments. The initial segment elucidates a series of synthetic works involving artificial molecules, specifically featuring the photosensitive azobenzene. These molecules facilitate remote control over the structure and functionality of biomolecules, with subsequent applications in regulating biological processes. The latter segment concentrates on the design and enhancement of organic photocatalysts, utilizing traditional acridine ions as a foundation. This section details the development of diverse organic photocatalyst-promoted processes, including photo Lewis acid catalysis, photo Brønsted acid catalysis, and photoredox reactions.

Grandparenthood And Psychological Well-Being Of Middle-Aged And Older Adults: Multigenerational Family Relationships In China, Dandan Zhao

Electronic Theses & Dissertations (2024 - present)

This dissertation examines whether and how experiences of grandparenthood—including becoming a grandparent, providing grandchild care, living with grandchildren, and exchanging intergenerational support—affect the well-being of middle-aged and older adults in China. Drawing on data from the China Health and Retirement Longitudinal Study (CHARLS, 2011–2018), a nationally representative survey of Chinese adults aged 45 and older, the study employs Ordinary Least Squares (OLS) regression and random effects models to investigate the associations between multigenerational family relationships and depressive symptoms among this population.

There is limited evidence that the transition to grandparenthood itself has a significant impact on psychological well-being. However, patterns …

The Rights Of Nature Meaning-Making Experiments In Ecuador: A Pragmatist Inquiry, Lourdes Aguas Gonzalez

Electronic Theses & Dissertations (2024 - present)

Ecuador is the first and only country in the world to recognize nature as a subject of rights in its national Constitution, with the most court cases to date, and with a vibrant moral imagination regarding the more-than-human world. Building on the pragmatist tradition, my research examines three questions: What are the rights of nature in Ecuador? How is nature politically represented in Ecuadorian legal forums? And how can collective problem-solving experiments around the rights of nature in Ecuador inform moral inquiry? To answer these questions, I bring sociology in conversation with philosophy. My theoretical and methodological tools as a …

Nat10 Stabilizes Immune Response Factors Aiding With Cellular Immune Response To Zika Virus Infection, Shawn Gianola

Electronic Theses & Dissertations (2024 - present)

Zika virus (ZIKV) remains a significant public health concern due to major gaps in our understanding of its infection mechanisms and immune evasion strategies. Despite its link to severe complications such as microcephaly and Guillain-Barré Syndrome (GBS), no vaccine or targeted antiviral therapies exist. Compounding this concern is the expanding habitat of ZIKV-carrying mosquito vectors, driven by climate change, which increases the risk of future outbreaks in previously unaffected regions.

One promising area of investigation involves post-transcriptional modifications (PTMs) chemical alterations to RNA that influence its stability, translation, and function. Although over 170 PTMs have been identified, their roles remain …

A Multi-Variate Rotating Machinery Fault Optimization And Recognition Framework, Ahmed M. Abdelrahman, Amira Y. Haikal, Mahmoud M. Saafan

Mansoura Engineering Journal

Accurate diagnosis, prognosis, and forecasting of a machine's time-to-failure are crucial through the massive, profound monitoring parameters and expeditiously is essential to assist in the preservation of reliability and life remaining for the machine increase by recommending an appropriate decision to diminish the occurrence of ruinous malfunction and substantial financial losses proactively. Artificial intelligence is considered significantly crucial to specialists in diagnosing various faults. But all research, although have great accuracy, still till now have a lack on the number of considering parameters to achieve the diagnosis or prognosis.in addition to, it depends on repeat the processing for sensor reading …

Optimal Design Of An Off-Grid Hybrid Renewable Systems With Battery Storage For Rural Electrification Of Academic Community In Ibogun Campus, Nigeria, Ayodeji Akinsoji Okubanjo, Alexander Okandeji, Ignatius Kema Okakwu, Benjamin Akinloye, Abisola Olayiwola

Mansoura Engineering Journal

In an era where the debate on climate action has evolved from mere awareness to urgent implementation, energy-efficient management strategies are crucial. The energy mix, combined with optimal design of hybrid renewable energy systems, is a potential option to limit the increase in demand for fossil fuels and the climate issue. As a result, this study proposes an optimal design of hybrid renewable systems using technoeconomic criteria to meet load demand in the Department of Electrical and Electronics Engineering at Olabisi Onabanjo University. The model combines an off-grid energy alternative with a battery storage system. The primary goal is to …

Relative Seat Height Effects On Knee Joint Kinematics In Older Adults, Sadie N. Zimmerman

Research Papers

No abstract provided.

Sustainable Hospitals Lighting Design Optimization To Enhance Patient Well-Being, Merna R. Ashac, Rania F. Ismail, Nasreen Fathy Abdelsalam

Mansoura Engineering Journal

This research investigates the critical role of lighting design in hospitals environments, focusing on its impact on patient outcomes and environmental sustainability. By integrating energy-efficient LEDs and natural light, the study aims to enhance patient well-being and staff performance. To achieve this, the research explores aligning artificial lighting with circadian rhythms to improve both patient outcomes and staff performance. Using mixed-methods approach, the research includes a literature review, case studies, and analysis using DIALux simulation software. The literature review achieves a framework for sustainable, human-centric lighting, while case studies provide practical insights into effective designs in patient rooms. DIALux simulations …

Eros And The Sublime: Tools For Reaching Toward An Altered Ecological Consciousness, Aineka Carlson

Graduate Student Theses, Dissertations, & Professional Papers

This thesis explores connections between the Kantian sublime and Anne Carson’s ideas regarding “eros.” Since Kant’s Critique of Judgement was published in 1790, the Kantian sublime has grown in popularity and been utilized by theorists and creative writers alike. While the Kantian sublime is often associated with nature in popular culture, there are certain egocentric and phallocentric elements of this mode of thinking that might inhibit a biocentric mindset. Through a character study of Oryx from Margaret Atwood’s novel Oryx and Crake, this thesis draws relations between the subjugation of women, nature, and the ways in which the popularized …

The Filament, Elena Skibicki

Graduate Student Theses, Dissertations, & Professional Papers

The Filament weaves together the results of a neurodivergent person exploring their universe, in all its harrowing beauty and familiar tragedy. The speaker traverses oceans and thunderstorms, wades through the swampy shallows of their high school, participates in a pharmaceutical supply chain and its subsequent ransacking, floats through altered mental states, and retells legends, spanning many styles while still using the lyric “I”. Scrying into a nebulous future, the speaker returns with stories of the planet and its people, and the kind of world they want to build.

The speaker exposes their ghosts throughout the collection, hoping that the adage, …

Perceived Ostracism And Fathers’ Experiences Of Grief And Trauma After Miscarriage, Eric D. Wesselmann, Jordan A. Arellanes, Leandra Parris

Faculty Publications – Psychology

Miscarriage can be a traumatic experience with serious mental health implications for parents. However, fathers’ experiences and outcomes post-miscarriage are understudied compared to those of mothers. Previous research focused on mothers’ experiences found that perceived ostracism correlated with grief intensity and posttraumatic stress symptoms, predicting unique variance in symptoms beyond grief intensity factors. We replicate several of these research findings in a sample of fathers and demonstrate that their perceived ostracism correlated positively with posttraumatic stress symptoms and negatively with grief reality (i.e. the pregnancy did not feel real to them). Perceived ostracism also explained additional variance in posttraumatic stress …

Autism Is Black Too! Intersectional Experiences With Service Provision For Black Autistic Individuals And Their Families, Brea M. Banks, Tyra Jackson, Randi Goodwin, Raven Moore

Faculty Publications – Psychology

We aimed to address a gap in the literature surrounding the experiences of Black autistic individuals and their families, specific to their engagement in the diagnostic process and service provision broadly. Our study was theoretically oriented in critical theories, as we aimed to push back against the dominant narrative about autism. We used qualitative methods and conducted interviews with Black autistic people (n = 2) and parents of Black autistic people (n = 9) to learn about their experiences. We employed an inductive approach to interpretation of data and used MAXQDA to engage in analysis. Results demonstrated that …

A Holistic Approach To Treatment Of Rosacea During Pregnancy: A Systematic Review, Emily Garelick, Margaret Hurley, Lauren Noto-Bell, Stefanie Cubelli

PCOM Scholarly Works

Background: Rosacea is a chronic inflammatory skin condition that is commonly exacerbated during pregnancy. Many patients suffer from emotional distress as a result of their rosacea, but the standard treatment options can cause harm to a developing fetus.

Methods: A systematic review was conducted on PubMed and EMBASE using the keywords “rosacea,” “pregnancy,” “treatment,” “holistic,” “edema, and “osteopathic manipulative treatment” (OMT). 113 papers were extracted and screened to determine eligibility based on inclusion criteria: primary sources, rosacea diagnosis, and documented treatment. Those that did not meet criteria were excluded and 20 papers remained for this review.

Results: The 20 included …

Multiple Myeloma Inhibitory Effects Of Natural Compounds: Enhancement Through Nanoparticle Carriers., Erica Wong, Anna Staskiewicz, Joshua Pruner, Jean Lee, Michael Tucker, Barkley Smith, Lanerica Rogers, Ganiat Asuni, Xinyu Wang

PCOM Scholarly Works

Natural compounds have emerged as promising therapeutic agents for treating cancers such as multiple myeloma (MM). However, poor bioavailability, low stability, and suboptimal targeting often limit their clinical efficacy. Recent advances in nanotechnology have addressed these limitations by utilizing nanoparticle (NP) carriers to enhance the therapeutic potential of natural compounds through improved solubility, stability, and selective delivery to cancer cells. This review explores the inhibitory effects of key natural compounds on MM cells, including 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) and its derivatives, caffeic acid phenethyl ester (CAPE) and its derivatives, xanthohumol (XN) and its derivatives, resveratrol (RSV) and its derivatives, curcumin (CUR), …

Detection Of Radiosensitive Subpopulations Ex-Vivo With Raman Microspectroscopy, Aidan D. Meade, Adrian Maguire, Jane Bryant, Daniel Cullen, Dinesh Medipally, Lisa White, John Armstrong, Mary Dunne, Emma Noone, Shirley Bradshaw, Marie Finn, Aoife M. Shannon, Orla L. Howe, Fiona M. Lyng

Articles

Although significant advances in understanding the molecular drivers of acquired and inherited radiosensitivity have occurred in recent decades, a single analytical method which can detect and classify radiosensitivity remains elusive. Raman microspectroscopy has demonstrated capabilities in the objective classification of various diseases, and more recently in the detection and modelling of radiobiological effect. In this study, Raman spectroscopy is presented as a potential tool for the detection of radiosensitivity subpopulations represented by four lymphoblastoid cell lines derived from individuals with ataxia telangiectasia (2 lines), non-Hodgkins lymphoma, and Turner's syndrome. These are classified with respect to a population with mixed radiosensitivity, …

Mineralization, Characterization And Selective Degradation Of Lignocellulosic Biocomposite Materials, Steven A. Soini

Electronic Theses and Dissertations

Developing novel functional materials, chemicals and biofuels from renewable plant sources has become a main area of focus within material science. The biosphere contains naturally occurring polymers that can be harvested to this end. Lignocellulosic materials are an important class of plant biomass consisting of three main components, cellulose, hemicellulose, and lignin. Wood has an inherent 3D hierarchical structure ranging from the nano- to bulk levels of organization, thereby achieving excellent mechanical properties while maintaining high porosity and low specific density. It carries significant promise for the production of chemicals, refinement of biofuels, and the development of novel functional materials. …

Predicting Early Hospital Readmissions For Diabetic Patients Using Machine Learning, Amanda Ferraz, Leonardo Oliveira

ICT

This project applies machine learning to predict whether diabetic patients will be readmitted to a hospital within 30 days of discharge. Early readmissions are a costly and critical issue in healthcare, often signalling gaps in post-discharge care and risk management. Diabetic patients face unfair high readmission rates compared to the general population. According to the CDC Diabetes Report Card 37.3 million people in the U.S. or 11.3% of the population had diabetes as of 2019 (CDC, 2021). Our goal here is to develop a binary classification model capable of flagging high risk patient (< 30-day readmission) based on their clinical, demographic, and administrative data. This lets healthcare institutions to take measures,