Digital Commons Network^™

Time To Reassess: Campus Programming In The First Six Weeks And Its Impact On Belonging For First-Time Students, Joe Smith

Masters Theses

Research has shown that a student’s first six weeks of college have a strong impact on the rest of their college experience. Because of this, institutions concentrate programming efforts in the first six weeks of the academic year to increase the likelihood of positive outcomes for their first-time students. However, little research has been done on this topic in recent years. This quantitative study sought to examine first-time student event attendance in the first six weeks of the academic year and its impact on sense of belonging, which has been shown to be an important factor of the college experience. …

Enhancing Sunflower Regeneration: Molecular And Genetic Insights From Helianthus Eggertii, Owen West

Masters Theses

In vitro plant regeneration, particularly through organogenesis and somatic embryogenesis, is essential for plant transformation and crop improvement, especially in recalcitrant species like sunflower. In this study, we explore the genetic and molecular mechanisms underlying regeneration in Helianthus eggertii, a wild sunflower species with high regeneration potential. Global gene expression profiling, conducted using Oxford Nanopore sequencing across multiple time points and genotypes, identified sixty-three core differentially expressed genes (DEGs) critical to regeneration. These DEGs are associated with critical biological processes such as cell proliferation, transcriptional regulation, and photosynthesis. Among them, a sunflower WUSCHEL-related homeobox transcription factor (WOX4) showed preferential expression …

Thermal Thresholds Of The Green Sunfish Lepomis Cyanellus: Insights Into Fish Vulnerability To Changes In Environmental Temperature, Noah W. Wright

Masters Theses

As global temperatures continue to rise, understanding the physiological responses of aquatic organisms becomes increasingly important. Elevated temperatures can significantly impact behavior, metabolism, and other essential survival processes. One species of particular interest is the Green Sunfish (Lepomis cyanellus), a member of the Centrarchidae family known for its relative thermal resilience compared to other congeners across the Midwest, a region already experiencing rapid warming due to climate change. L. cyanellus are not invulnerable to thermal stress, and recent evidence suggests that both performance and thermal tolerance decline under sustained temperature increases. In this context, evaluating their response to …

Spatiotemporal Variability In Invasive Carp Spawning Activity In Two Midwestern River Basins, Braden A. Whisler

Masters Theses

Across the United States, fisheries managers and agencies continue to battle the spread of invasive bigheaded carp (Hypophthalmichthys spp.). Although previous research has identified environmental parameters such as temperature and flow to be triggers of spawning activity, many of these studies focus on larger rivers, rarely focusing on the specific thresholds or timing of when a spawning event takes place. I utilized the differing hydrology of the Illinois and Wabash Rivers and their tributaries to examine the differences in environmental parameters needed to trigger bigheaded carp reproduction. Three mainstem sites and three tributaries of both basins were sampled …

Assessing Ecological And Food Web Responses To Small-Scale Stream Restorations In Urban And Agricultural Streams, Sydney Mcandrews

Masters Theses

Urban and agricultural streams across the Midwestern United States are vulnerable to elevated pollution, eutrophication, habitat simplification, and losses of sensitive species. Instream habitat restoration is increasingly used to mitigate the impacts of rapid land-use change. This study synthesizes habitat and biological responses from a 2020 urban stream restoration in the Saline Branch (Urbana, Illinois) and evaluates food web responses from both the Saline Branch and a 2010 restoration in Kickapoo Creek (Charleston, Illinois), an agricultural stream. In the Saline Branch, four years of fish and three years of habitat and macroinvertebrate pre-restoration surveys were compared to three years of …

Chronic Administration Of A Cannabis-Derived Mixture At An Antihyperalgesic Dose Does Not Significantly Enhance Hepatotoxicity Or The Development Of Metabolic Dysfunction-Associated Steatohepatitis In Male Mice, Kim B. Pedersen, Tomislav Jelesijevic, Tamara M. Morris, Sarah M. Melton, Ashley S. Henderson, John F. Glenn, Gregory J. Davenport, Martin J.J. Ronis, Peter J. Winsauer

School of Medicine Faculty Publications

Cannabis and cannabinoid mixtures have been linked to a variety of health benefits including pain mitigation, suppression of nausea produced by chemotherapeutic agents, anti-inflammatory effects, and effects on energy homeostasis, glucose, and lipid metabolism. The latter properties have led to the suggestion that these products could have therapeutic effects on the development of metabolic dysfunction-associated steatohepatitis (MASH) - a severe type of liver pathology in obese and diabetic patients. However, varying agonist and antagonistic properties of different cannabinoids on the endogenous cannabinoid system make prediction regarding hepatic effects and diet interactions difficult. The current study was designed to examine hepatic …

Environmentally Persistent Free Radicals Lead To Selective Inhibition Of Cyp1 Monooxygenase Activities, And Increased Production Of Reactive Oxygen Species By Reaction Uncoupling, John Patrick Connick, Amari A. Stepter, George F. Cawley, Marilyn K. Eyer, Wayne L. Backes

School of Medicine Faculty Publications

This study focuses on the effect of Environmentally Persistent Free Radicals (EPFRs) on the P450 enzymes of the CYP1 family. EPFRs are a component of particulate pollutants, that are stable in the environment, but can generate free radicals, leading to oxidative stress and subsequent toxicity of the respiratory, cardiovascular, and immune systems once they enter an organism. The results show differences in the ability of EPFRs to inhibit CYP1-dependent substrate metabolism, with CYP1B1 being inhibited to the greatest extent. There also were differences in the ability of EPFRs to disrupt the POR•CYP1 complex, with CYP1B1 being the only form where …

Allodus Podophylli: The Infection Cycle Of Mayapple Rust, W. John Hayden

Biology Faculty Publications

This article addresses the parasitic fungus, Allodus podophylli, that causes Mayapple Rust. This disease is extremely common throughout the entire geographic range of Mayap-ple, Podophyllum peltatum, the 2025 VNPS Wildflower of the Year.

Wildflower Of The Year; Mayapple (Podophyllum Peltatum), W. John Hayden

Biology Faculty Publications

Mayapples are perennial herbaceous plants with thick fibrous roots that arise from a creeping rhizome.

Early Cerebrospinal Fluid Elevations Of Ptau-217 In Severe Traumatic Brain Injury Subjects, Hamad Yadikar, Firas H Kobeissy, Claudia Robertson, Spyridoula Tsetsou, John B Williamson, Damon G Lamb, Amy K Wagner, Todd Kibaugh, Shih-Han Kao, Zhifeng Kou, Robert D Welch, Jose-Miguel Yamal, Luis Leon-Novelo, Richard Rubenstein, Kevin K W Wang

Faculty, Staff and Students Publications

Introduction: Tauopathies, including Alzheimer's disease (AD), feature abnormal accumulations of hyperphosphorylated Tau protein; however, their biomarker potential in traumatic brain injury (TBI) is not well-defined. This study investigated whether cerebrospinal fluid (CSF) phosphorylated Tau at threonine-217 (pTau-217) could serve as an early biomarker for severe TBI (sTBI).

Methods: CSF samples from 26 sTBI patients, collected between 6 and 240 h post-injury, and 19 healthy controls were analyzed using an optimized direct enzyme-linked immunosorbent assay (ELISA; sensitivity < 4.7 pg/mL) for pTau-217 detection, complemented by Western blot validation. Temporal analysis, ROC curves, and trajectory clustering were used for interpretation.

Results: CSF pTau-217 levels were significantly elevated in sTBI patients at 6, 12, 18, 24, and 48 h post-injury compared to controls (p …

Egalitarianism Is Not Equality: Moving From Outcome To Process In The Study Of Human Political Organisation, Duncan Stibbard-Hawkes, Christopher Von Rueden

Jepson School of Leadership Studies articles, book chapters and other publications

Many traditional subsistence groups have been described as ‘egalitarian societies’. Definitions of ‘egalitarianism’, especially beyond anthropology, have often emphasised equality in resource access, prestige or rank, alongside generalised preferences for fairness and equality. However, there are no human societies where equality is genuinely realised in all areas of life. Here we demonstrate, empirically, that nominally egalitarian societies are often unequal across seven important interconnected domains: embodied capital, social capital, leadership, gender, age/knowledge, material capital/land tenure, and reproduction. We also highlight evidence that individuals in nominally egalitarian societies do not unfailingly adhere to strong equality preferences. We propose a new operational …

Nanoparticle Contrast-Enhanced Computed Tomography Of Sporadic Aortic Aneurysm And Dissection: Effect Of Nanoparticle Size And Contrast Agent Dose, Laxman Devkota, Chen Zhang, Deborah Vela, Poonam Sarkar, Prajwal Bhandari, Zbigniew Starosolski, Renuka Menon, Dianna M Milewicz, Ying H Shen, Scott A Lemaire, Ketan B Ghaghada

Faculty, Staff and Students Publications

Background: Aortopathies, such as aortic aneurysm and dissection (AAD), are associated with enhanced aortic wall permeability and endothelial dysfunction. We previously demonstrated that nanoparticle contrast-enhanced computed tomography (nCECT), which detects enhanced aortic wall permeability, could enable non-invasive detection of early AAD before its progresses to fatal aortic rupture. This study investigated the effect of nanoparticle contrast agent (NPCA) size and dose on detection of aortopathy by nCECT.

Methods: In vivo studies were performed in a mouse model of sporadic AAD induced by challenging animals with high fat diet (5 weeks) and angiotensin II infusion (last one week). The effects …

Contributions Of Pathobiological And Translational Science To Understanding And Managing Ischemic Heart Disease: Progress, Impediments, And Future Directions, L Maximilian Buja

The Texas Heart Institute Journal

Key pathobiological components of ischemic heart disease have been identified as follows: (1) In 1970 to 1973, myocardial infarct size was found to be the primary determinant of prognosis after acute myocardial infarction (AMI); (2) in 1973 to 1989, vulnerable coronary artery plaques were found to predispose individuals to coronary plaque disruption and thrombosis, causing major AMI; (3) in 1972, timely coronary reperfusion was demonstrated to limit the size of evolving AMI but with risk of reperfusion injury; and (4) in 1986, myocardial conditioning was found to be a clinically significant modulator capable of delaying AMI progression. Promising cardioprotective strategies …

Age-Related Variations In Hba1c Improvemecnts: Insights From A Telehealth-Supported Community-Based Intervention, Laura Porterfield, Xiaoying Yu, Amber B Amspoker, Craig A Johnston, Aanand D Naik, Salim S Virani, Christie M Ballantyne, Ashok Balasubramanyam, Elizabeth M Vaughan

Faculty, Staff and Students Publications

Background and objectives: We previously demonstrated that a telehealth-supported community health worker (CHW) intervention significantly improved clinical outcomes in diabetes care. However, the extent to which these benefits vary across different age groups remains unclear. This study evaluated the effectiveness of a CHW-led multidimensional diabetes intervention in reducing HbA1c across age groups.

Research design and methods: We conducted a retrospective analysis of 10 studies (n = 301) that focused on low-income Hispanic adults with or at risk for type 2 diabetes. The intervention included CHW-participant coaching via mobile Health (mHealth), monthly CHW-led group education, and bidirectional mHealth feedback among …

Leading Organizational Learning Through Stories In U.S. “Big Technology” Companies, Stephanie R. Voss

Theses and Dissertations

Storytelling is becoming increasingly influential across various domains, particularly in executive education and leadership development, where it plays a crucial role in the concept of leadership as performance (Gonzalez & Chakraborty, 2012). Storytelling in the classroom setting provides an opportunity for learners to embed elements of narrative and identity in classroom pedagogy (Edwards et al., 2013). In the professional context, employees construct meaning in their workplace by hearing and/or participating in stories (Echeverria et al., 2017).

This qualitative exploratory study investigates the influence of storytelling in driving organizational learning. The research focuses on the U.S. Big Technology (Tech) sector, home …

Assessment And Treatment Outcomes Of Women Experiencing Miscarriage And Pregnancy Loss: A Systematic Review Of The Literature, Hanieh Fakhrai

Theses and Dissertations

This systematic review examined the assessment tools, mental health outcomes, supportive resources, and intervention strategies related to women experiencing miscarriage and pregnancy loss. Despite affecting 10-20% of recognized pregnancies, the psychological impact of miscarriage is often overlooked in healthcare settings. Following PRISMA guidelines, 18 studies published between 2010-2021 from diverse international contexts were systematically analyzed. Findings revealed significant mental health consequences, including depression (prevalence 31-48.8%), anxiety (2.4-61%), and PTSD symptoms (14.7-43.9%). Risk factors for adverse outcomes included previous mental health conditions, history of infertility, multiple pregnancy losses, and difficulty finding meaning. Women identified helpful, supportive resources, including internet forums, sensitive …

Current Trends In Assessment Training At Clinical Psychology Doctoral Programs, Darcy Perrin Darrell

Theses and Dissertations

Psychological assessment is a fundamental competency in clinical psychology doctoral training, yet inconsistencies persist in the content and structure of assessment education across programs. This study aimed to evaluate current trends in psychological assessment training at American Psychological Association (APA) accredited clinical psychology doctoral programs, with particular attention to the implementation of the APA Guidelines for Education and Training in Psychological Assessment in Health Service Psychology. Utilizing a nonexperimental, descriptive design, the study analyzed 85 syllabi submitted by 58 programs, as well as publicly available curricular information. A rubric was developed to assess the extent to which course syllabi reflected …

Best Educational Practices For Supporting English Learners During Remote Learning, Dimitrina S. Gotzeva

Theses and Dissertations

Remote learning (RL) has gained significant momentum in recent years, particularly following the COVID-19 pandemic lockdown, underscoring the need for technology to facilitate remote education. Despite its increased prominence, RL has been a long-standing educational tool, enabling students to access quality education even when physically distant from prestigious institutions. However, the effectiveness of RL has been a topic of ongoing debate, with no clear consensus in the literature on the optimal strategies to enhance its outcomes. Focusing on English language learning, this study aimed to investigate the challenges and barriers associated with RL and identify effective strategies to improve its …

The Effects Of Exposure To War & Attachment Disruption On Children Of War Leading To Negative Mental Health Outcomes, Chantal Daley

Theses and Dissertations

Children of war tend to endure abuse, witness deaths, killings, and sexual violence, and are also often coerced into committing violent acts. They are subjected to exposure to war-related traumas and as a result often become displaced from their primary caregiver and attachment figure and this relationship is disrupted. The primary aim of this systematic review was to explore the negative mental health outcomes in children of war into adulthood following attachment disruption and exposure to war. It also aimed to examine what protective factors mitigated these negative mental health outcomes and whether outcomes and protective factors varied according to …

Remove The Invisibility Cloak - Let's Get Women Promoted!, Nina Echeverría Brown

Theses and Dissertations

This two-study research project uses a mixed-methods exploratory sequential research design to investigate the career journey of women in Corporate America and assess how they navigate the tensions that may impede Career Growth. Study 1 employs qualitative interviews to gather insights from 20 diverse women at varying managerial levels. Thematic analysis reveals five primary Pathways to Career Growth—Foundational Development, Social Augmentation, Adaptive Knowledge Expansion, Forward Focus, and Visibility—each associated with specific strategies that women employ to navigate tensions related to Cultural, Organizational, and Domestic spheres. Study 2 builds upon these findings and utilizes quantitative cross-sectional survey data from 385 corporate …

Navigating The New Normal: A Grounded Theory Study Of Lessons Learned About Leadership Practices Since The Pandemic In Multimodal Workplace Settings And The Future Of Work, Jessica Arriaza

Theses and Dissertations

The global pandemic has profoundly transformed leadership and the work landscape across multimodal workplace environments (onsite, virtual, and hybrid). As organizations navigated unprecedented disruption, leaders had to respond with agility, empathy, and innovation. This qualitative, grounded theory study explored the transformative impact of post-pandemic changes on leadership practices within the evolving workplace landscape and future work trends. The overarching research question guiding this study was to what extent, if at all, leadership practices have evolved since the global pandemic across onsite, virtual, and hybrid workplace settings, and what skills, strategies, and practices will future leaders need to navigate the future …

Educating Outdoors: A Qualitative Case Study On School Readiness Development In A Nature-Based Preschool, Lauren Lefevre

Theses and Dissertations

Play is widely considered one of the most crucial activities for healthy early childhood development, yet many current early childhood education (ECE) programs prioritize academics at the expense of this critical activity. Despite this focus on math and literacy skills, a significant number of children arrive at kindergarten unable to demonstrate proper school readiness. Nature-based early childhood education (NbECE) is a growing alternative education option that prioritizes risky play, loose parts play, and nature play, potentially providing children with countless opportunities for school-readiness development through play. Guided by the biophilia hypothesis (Wilson, 1984), which suggests that humans are innately drawn …

Ai: A Path Forward In Education - Teachers’ Insights On Implementation, Challenges, And Future Innovations, Mercedes Cordoba Meeks

Theses and Dissertations

Artificial intelligence (AI) is a global phenomenon permeating the fabric of society and transforming the course of culture and commerce (Kishor et al., 2023; Moore, 2024). A review of the extant literature indicates that while many industries have seen significant innovations due to the infusion of AI, the field of education has witnessed a technological evolution inspired by AI-based tools and strategies (Bessen, 2018; W. M. Lim et al., 2023). Artificial Intelligence in Education (AIED) has a history that parallels the development of AI. AIED has shown steady growth and influence in educational programs around the world, with the growth …

Computational Modeling Of The Heat Treatment Of White Oak Bound For Spirit Maturation, Kate E. Mclarney-Popham

Theses and Dissertations--Chemical and Materials Engineering

Maturation of distilled spirits in white oak barrels is a long standing practice known to have great impact on spirit character. Much of this impact can be controlled by the thermal modification of the barrel, since thermal degradation of the wood determines what wood compounds are available to interact with the spirit during maturation. In this work, a computational model for the thermal degradation of wood was developed and, with flavor compound data from literature, was used to investigate the effect of heat treatment on lignin-derived flavor compounds. The computational model in this work accounted for three solid species, three …

Microstructural Characterization Of Complex Metal Alloy Systems With A Focus On Electron Microscopy, Alexandra Allamon

Theses and Dissertations--Chemical and Materials Engineering

Multi-principal element alloys (MPEAs)/high-entropy alloys (HEAs) are a class of materials that provide novel and superior combinations of properties, with promise for use in challenging application areas that many of the current established materials cannot fit. With a higher number of constituent elements, many of the newly created alloys are compositionally complex in nature, known to contain combinations of relatively soft FCC phases, hard BCC phases, and, in some cases, even harder intermetallic phases. Microstructural study of these new materials is essential to understanding the enhanced properties they may possess, but their complexity can make this study much more challenging …

Ion Hydration In Bulk And Nanoconfined Water: Insights From Machine Learning Force Fields, Zachary D. Baker

Theses and Dissertations--Chemical and Materials Engineering

Understanding ionic hydration remains a central challenge in physical chemistry and materials science, as the interactions between ions and water molecules govern diverse phenomena ranging from electrolyte transport to selective ion separation. While experimental techniques have provided invaluable insights into solvation energetics and coordination numbers, they often lack atomistic resolution, particularly under nanoscale confinement where direct measurement becomes infeasible. Molecular dynamics (MD) simulations can bridge this gap; however, conventional classical force fields are limited by their simplified, fixed functional forms and empirical parameterization, whereas ab initio molecular dynamics (AIMD) achieves higher accuracy at the expense of severe computational cost and …

Arthroscopic Rotator Cuff Repair With Or Without Acromioplasty, Mohamed Aboelnour Badran, Ahmed M. Barakat, Osama Samir Gaarour, Roshdy Mostafa El-Sallab

Mansoura Medical Journal

Background: Rotator cuff tears are a major cause of shoulder disability, particularly among individuals over 60 years of age. While subacromial decompression, including acromioplasty, has been traditionally performed during rotator cuff repair (RCR) to alleviate impingement and prevent re-tears, recent studies have questioned its necessity. This study aims to compare outcomes of RCR with and without acromioplasty. Objective: To evaluate the functional, radiological, and complication-related outcomes of rotator cuff repair with subacromial decompression versus rotator cuff repair alone in adult patients with rotator cuff tears. Methods: This retrospective comparative study was conducted at Mansoura University Hospitals between 2021 and 2024, …

Impacts Of Age And Androgen Level On Albino Rat Meibomian Gland: Light & Electron Microscopic Study, Amira A. Hamid, Nawal A. Hasanin, Hanaa A. Khalaf, Walaa H. E. Hamed

Mansoura Medical Journal

Background: Histological changes in albino rats meibomian glands in relation to age and androgen level. Aim of the work: The current research attempted to assess the impact of age and androgen level on histological structure of meibomian gland . Material and methods: Three groups of adult male albino rats were used ,each group comprised ten rats, group I: six months, group II: one year and group III : two years, Each animal at proper age was weighed , anaesthetized and blood samples were collected for estimation of dehydro-epiandrosterone (DHEA) hormone . The eyelids of each rat were dissected and prepared …

Role Of Magnetic Resonance Diffusion Tensor Imaging In Differentiating Osteomyelitis From Osteoarthropathy In Diabetic Foot, Mona Mohamed Hamid Ibrahim Barakat, Saher Ebrahim Taman, Samer Abdelhamid Regal, Ahmed Galal Sadek

Mansoura Medical Journal

Background: Diabetic foot ulcer (DFU) represents a major cause of preventable morbidity among adults with diabetes mellitus (DM). Diabetic foot osteomyelitis (DFO) frequently arises through contiguous spread of soft tissue infection to the underlying bone. Diffusion tensor imaging (DTI) is an advanced magnetic resonance imaging (MRI) technique that enables quantitative evaluation of tissue microstructure. Aim: To assess the diagnostic value of magnetic resonance DTI in differentiating osteomyelitis from acute osteoarthropathy in patients with diabetic foot complications. Methods: This prospective study included 28 diabetic patients presenting with clinically suspected foot complications. According to the final diagnosis, patients were classified into two …

Medical Students’ Disaster-Specific Self-Efficacy And Willingness To Respond Following An Introductory Preparedness Training, Brooke Wagner, Libby Washburn, Joseph D Visker, Carol Cox

Health Professions Education

Purpose.

The purpose of this cross-sectional study was to examine medical students’ disaster self-efficacy and willingness to respond to disasters before and after attending an introductory disaster preparedness training program during fall 2023.

Method.

Medical students (eight Year 1 and 18 Year 2) attending a one-day introductory disaster preparedness program that focused on an all-hazard approach and used lecture and applied scenario practice instruction were surveyed pre-post program using a written, four-section questionnaire on their disaster-specific self-efficacy and willingness to respond to disasters. Statistical analyses were conducted using IBM SPSS Statistics (v29) and primarily consisted of descriptive statistics (frequencies and …