Digital Commons Network^™

Cooperative Role Of Distinctive Tp53 And Pten Combined Loss In The Peripheral T Cell Lymphoma-Gata3 Molecular Subgroup, Waseem G. Lone, Jiayu Yu, Xuxiang Liu, Dylan T. Jochum, Alyssa Bouska, Kunal Shetty, Tyler Herek, Sunandini Sharma, Chengfeng Bi, Rauf Shah, Zaina W. Nasser, Catalina Amador, Aiza Arif, Abdul Rouf Mir, Yuping Li, Tayla B. Heavican-Foral, Jacob Robinson, R. Katherine Hyde, Mamiko Sakata-Yanagimoto, Satyanarayana Rachagani, Timothy W. Mckeithan, David W. Scott, Louis M. Staudt, Giorgio Inghirami, Andrew Feldman, Timothy Greiner, Julie M. Vose, Lisa Rimsza, Joseph Khoury, Wing C. Chan, Javeed Iqbal, Lymphoma/Leukemia Molecular Profiling Project (Llmpp)

Journal Articles: Oncology and Hematology

Peripheral T cell lymphoma (PTCL) is a heterogeneous group of postthymic T cell neoplasms, with ~40% classified as PTCL-not otherwise specified (PTCL-NOS). PTCL-GATA3, a molecularly defined subtype, associated with T helper 2 (T_H2)-like differentiation and poor prognosis, has frequent co-occurrence of TP53 loss/mutation and heterozygous PTEN loss. CD4+ T cell conditional mouse models with Trp53 mutation/deletion and Pten loss demonstrated mature T cell lymphomas (mTCLs) with T_H2-like transcriptomic and immunophenotypic profiles. Molecular studies revealed that codeletion of Trp53/Pten induced T cell receptor and Janus kinase-signal transducer and activator of transcription signaling, promoting T_H2 differentiation …

English Textbooks In The Modern World : Cultural Representation In An Efl Textbook From Vietnam, Khoi Tan Minh Vuong, Wannapa Trakulkasemsuk

PASAA

No abstract provided.

How To Elevate Your Note-Taking Skills, Alexander Cho

ENGS 15.11: Design and Education

One of the most crucial skills a student can have is effective and efficient note-taking abilities. Therefore, this interactive lesson transforms note-taking from a passive recording activity into an active learning strategy. Through discussions, activities, and reflections, students will understand the importance of note-taking, then learn techniques to take better notes before, during, and after class. Afterwards, we will dive into 4 different note-taking methods and students will be able to adapt these techniques to different content types, and develop personalized systems for review.

Osteophone To Detect Fracture In The Field, Noah Dunleavy, Micah Green, Hannah Chipman, Gabe Landi, Kai Etheridge

ENGS 89/90 Reports

When assessing long bone fractures, X-ray is the state-of-the-art solution. However, its inaccessibility due to cost and distance poses a barrier to nearly half of the global population, and this lack of access inhibits prehospital triage and assessment. Currently, there are no affordable, portable options that can not only rule out— but also detect the presence of— fracture. We are developing a device that implements the principles of sound wave attenuation that underlie other state-of-the-art alternatives to X-ray, such as the clinician administered tuning fork and stethoscope method, but with improved accuracy and objectivity. This approach uses a microcontroller to …

A Closer Look At 4c Skills Integration In English For Nursing Textbooks : A Content Analysis Approach, Fitri Handayani, M. Zaim, Havid Ardi

PASAA

No abstract provided.

The Effects Of Differentiated Pronunciation Instruction Via A Virtual Learning Environment On Primary-School Thai Efl Teachers, Sumanee Pinweha

PASAA

No abstract provided.

Establishing English Science Textbook Word Lists (Estwls) For Thai Efl Secondary Students : A Corpus-Based Approach, Thana Kruawong, Supakorn Phoocharoensil

PASAA

No abstract provided.

2025 Georgia Southern University Football Roster, Georgia Southern University

Men's Football Records

No abstract provided.

Building Design - Bsc App Tools For Structural Systems, Jens G. Pohl

Architecture

Relationship to Building Science (BSc) App: In the domain of Building Science (BSc), this paper focuses on building design principles related to building loads and the conceptual analysis and approximate sizing of structural members and structural systems. It provides direct access to a BSc App that offers more than 420 calculation and information functions in the entire range of building science areas, comprising daylighting, artificial lighting, noise control, room acoustics, climate and thermal comfort, solar energy, and structural systems (https://research.chobugroup.com/buildingscience/analyzer/).

Information Content: The paper briefly explains the structural concepts and principles that underlie the selection and approximate sizing of structural …

Understanding Bosnian Komšiluk: A Study Of Neighbourhood Dynamics And Violence, Sandra Grudić

Student Publications [Scholarly]

The 1990s war in Bosnia and Herzegovina was a top-down political project aimed at dividing the multiethnic state and it was characterized by neighbourhood violence. Following the war, scholars focused on understanding the meaning and significance of komšiluk (neighbourliness) in Bosnian culture, particularly in relation to how friendly neighbourly relations turned violent during the ethnic conflict. These scholarly debates have contributed to a better understanding of komšiluk, although it has typically been presented as a stable institution, often negotiated along an interethnic axis, and viewed as a concept that persisted unchanged over time, with near-universal characteristics throughout Bosnia. This paper …

Development Of Software For Genetic Distances, Genotyping, And Phylogenetics Using Rna-Seq Data, Andrew C. Tapia

Theses and Dissertations--Computer Science

This dissertation concerns a new application of RNA-seq data—computation of pairwise genetic distance matrices. RNA-seq captures sequences of RNA molecules in some cells or tissues of interest. RNA-seq provides data are well-suited to studies examining gene expression, and its use for this purpose is currently widespread. A pairwise genetic distance matrix, the main topic of this dissertation, quantifies differences in the genomes of every pair of samples (e.g., individuals) in a given set. Genetic distance matrices are versatile; they can be used for various kinds of downstream analyses, including genotyping, phylogenetics, and genetic diversity measurement. Although DNA sequence data are …

A Finite Volume-Based Approach For Modeling Hyperbaric Oxygen Therapy For Healing Chronic Wounds, Cade M. Layser

College of Graduate Studies: Theses & Dissertations

The current number of people in America with diabetes is approximately 38.4 million, that population is expected to rise to 54.9 million by 2030. Chronic wounds, which are characterized by impaired or stalled healing, are commonly associated with diabetes. These wounds if not treated properly can cause significant complications such as sepsis, infection, and gangrene which can lead to limb amputation or death of the patient. Limb amputations can be a large financial burden and significantly reduce the patient’s quality of life. The timely and efficient treatment of chronic wounds is essential to prevent adverse patient outcomes. Hyperbaric Oxygen therapy …

Long-Term Ichthyoplankton Monitoring Of The Moon River (Savannah, Ga) With A Focus On Climate Change, Bradley Cayson

College of Graduate Studies: Theses & Dissertations

The presence of healthy fish populations is a cornerstone of many important ecological mechanisms. These populations are supported by the recruitment of ichthyoplankton, or the egg and larval stages of fishes, as the primary determinant of population growth. Increases in average global water temperatures can alter the composition of fish communities and thus the offspring found in planktonic stages. I compared a large data set of ichthyoplankton surveys completed from 2009-2011 to a replicated six-month sampling period from May – November of 2024. Collection was conducted weekly to biweekly during night flood tides using a fixed suspension ichthyoplankton net (1mm …

Incarcerated Youth Returning To Society As Adults: An Examination Of Their Lived Experiences And Challenges, Kimberly R. Lawrance

Theses and Dissertations

When children have been incarcerated, they face collateral consequences that make it nearly impossible to recover from when they return home. Collateral consequences are the adverse effects experienced by incarcerated people and their families often causing restrictions or missed opportunities after interaction with the criminal justice system (Moise, Simonsen, & Kearl, 2023). Collateral consequences can be related to housing, employment, and education, to name a few. These lost opportunities are concerning for youth because most have never held a job or finished high school. Collateral consequences often set them up for failure leading to the revolving doors of jails and …

Exploring The Role Of Transcription Factor Nrf1 In Autophagy And Inhibiting The Nrf1 Bounce-Back Response, Madison A. Ward

Theses and Dissertations

Cells exposed to proteotoxic stress invoke adaptive responses aimed at restoring proteostasis. Our previous studies have established a firm role for the transcription factor Nuclear factor-erythroid derived-2-related factor-1 (Nrf1) in responding to proteotoxic stress elicited by inhibition of cellular proteasome. Following proteasome inhibition, Nrf1 mediates the synthesis of new proteasomes, thus enabling cells to mitigate proteotoxic stress. Here, we report that under similar circumstances, multiple components of the autophagy-lysosomal pathway (ALP) were transcriptionally upregulated in an Nrf1-dependent fashion, thus providing the cells with an additional route to cope with proteasome insufficiency. In response to proteasome inhibitors, Nrf1-deficient cells exhibited profound …

Folic Acid-Decorated Lipidic Nanocapsules Co-Loaded With Atorvastatin And Curcumin To Enhance Glioma Targeting In Mice, Mahitab Bayoumi, John Youshia, Osama Abdelkawy, Sara Abdelgaber, Mona Arafa, Maha Nasr, Omaima Sammour

Pharmacy

Background: Glioma remains an intractable and highly aggressive brain tumor, mainly due to the daunting obstacle presented by the blood-brain barrier (BBB). To overcome this challenge and enhance therapeutic efficacy, a dual-drug delivery system was engineered. This system co-encapsulated curcumin, a nutraceutical with multitargeted anticancer potential, with atorvastatin calcium, a repurposed anticancer agent, within lipidic nanocapsules (LNCs). Methods: LNCs were prepared via the phase inversion temperature method and optimized using a Box–Behnken design. The optimized LNCs were subsequently functionalized with folic acid (FA) to enable active targeting. FA-LNCs were characterized using, XPS, TEM, in vitro release, and MTT cytotoxicity …

Communities Of Stone Toolmakers Along The Lower Cumberland And Tennessee Rivers, Vanessa N. Hanvey

Theses and Dissertations--Anthropology

Concurrently occupied between circa 8,600-8,200 cal B.P., the Canton (15Tr1), Lawrence (15Tr33), Morrisroe (15Lv156), and Whalen (15Ly48) sites have similar stone tool assemblages. Though the sites are situated close to one another within the lower Tennessee and Cumberland River watersheds, the connection between the people who occupied each site remains unclear. Extensive lithic deposits representing all stages of tool manufacture were identified at both the Canton and Lawrence sites, and previous lithic analyses show that similar raw materials were being accessed by stone toolmakers at all four sites. To investigate the relationship between the people who occupied these sites, this …

Improving The Mechanical Performance Of 45s5 3d Scaffolds Through The Particles Of Barium Titanate Ceramics, Surirat Yotthuan, Usanee Pantulap, Nuttawan Sawangboon, Ornuma Tungsanguan, Ekarat Meechoowas, Kansiree Kaewmorakot, Nathaporn Uthaichai, Theerachai Bongkarn

Journal of Metals, Materials and Minerals

Bioglass® 45S5 is widely used in bone tissue engineering due to its excellent bioactivity. However, its low mechanical strength remains a major limitation. In this study, 25 wt% barium titanate (BaTiO3; BT) was incorporated into 45S5 scaffolds to improve mechanical performance and modulate bioactivity. The 3D scaffolds were fabricated using the foam replication method and exhibited interconnected porosity, with average pore sizes of 471 ± 94 μm (45S5) and 598 ± 58 μm (45S5/BT25), closely resembling human bone. The addition of BT increased the density and compressive strength of the scaffolds to 2.89 ± 0.18 g∙cm‒3 and 2.0 ± 0.2 …

Antibacterial, Self-Adhesive Guar Gum/Polyvinyl Alcohol/Tannic Acid Conductive Hydrogels For Flexible Strain Sensors, Noppanan Putdon, Somnuk Theerakulpistut, Rawit Jittham, Pornnapa Kasemsiri

Journal of Metals, Materials and Minerals

In this research, a multifunctional strain sensor with antibacterial properties and self-adhesion capabilities was developed using guar gum (GG), polyvinyl alcohol (PVA), and tannic acid (TA). The incorporation of TA into GG-PVA hydrogel-based strain sensors was investigated to evaluate its effects on mechanical and electrical properties, self-adhesion, and antibacterial activities. The anti-bacterial activities against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) were enhanced with the increasing content of TA. The adhesive strength was observed in the range of 1.20 ± 0.10 kPa to 5.05 ± 0.23 kPa, and the values tended to increase as TA content increased. The …

Mechanochemical Synthesis Of Ni(Ii)-Tptz Complexes With Co-Ligands: Spectroscopy, Dft, And Biological Studies, Deepak Senapati, Anulipsa Priyadarshini, Debadutta Samal, P. Ramesh Babu, Satyanarayan Sahoo, Narayan Chandra Bera, Raghabendra Samantaray, Jagannath Panda, Rojalin Sahu

Journal of Metals, Materials and Minerals

New mixed-ligand Ni(II) complexes [Ni(tptz)(1,10-phen)] (1), [Ni(tptz)(2-Mimd)2] (2), and [Ni(tptz)Imd)2] (3) were synthesized via a green, solvent-free mechanochemical approach using ball milling. The primary ligand used was 2,4,6-tris(2-pyridyl)-1,3,5-triazine (tptz), with secondary ligands being 1,10-phenanthroline, 2-methyl imidazole, and imidazole, respectively. Structural characterization by IR, UV-Visible, photoluminescence spectroscopy, and powder X-ray diffraction, supported by DFT calculations, revealed a distorted square planar geometry for complex 1 and distorted tetrahedral geometries for complex-2 and complex-3. Notably, bathochromic shifts in the UV-Vis spectra confirm metal-ligand charge transfer transitions and extended π-delocalization. Powder XRD analysis determined average crystallite sizes of 17.86 nm (1), 25 nm (2), …

Social Murder And The Antisocial Contract, Marissa Jackson Sow

Law Faculty Publications

Social murder is widely understood as the reckless and calculated killing by the State of people who are considered surplus and thus made redundant by the State. It is not merely an outcome, however; social murder, is an antidemocratic process, and—certainly as it is manifesting in the United States under the second Trump Administration—is also an anti-constitutionalist project aimed at destroying society, eliminating social goods, and renegotiating an American social contract that is, definitionally, antisocial. Social murder is as much about the elimination of social life as it is about the interruption of physical life. And it is fueled by …

Operationalizing A Pedagogy Of Antiracism In Legal Education, Doron Samuel-Siegel

Law Faculty Publications

To reckon with structural racism in legal education, legal educators collectively must do much more than we have done thus far. A true reckoning will occur only once we provide an education that ensures racially minoritized students can learn free of the harms of traditional legal education, and that all students are equipped to contribute to the dismantlement of structural racism in the law and legal profession. A pedagogy that centers these two goals counteracts the effects of structural racism while also creating conditions for its dismantlement, making it a pedagogy of antiracism.

This article is about moving toward the …

Coral Crisis: Palytoxin-Induced Keratoconjunctivitis In Marine Experts, Nikolas Foresteire, Luis Cabrera, Cory Howard, Alexandra Craen, Ori Gat

West Florida Division GME Research Day 2025

No abstract provided.

Inflammation Without Borders: A Rare Case Of Takayasu Arteritis In A Young Adult, Alexander Yaylayan, Walaa Abualhuda, Yash Dara, Joshini Simon, Jeffrey Steinhoff, Mark Starnes, Robert Digiovanni

West Florida Division GME Research Day 2025

No abstract provided.

Communiqué: College Of Humanities, Arts & Sciences Alumni Magazine, Volume 11, 2025, University Of Northern Iowa. College Of Humanities, Arts, And Sciences.

Communiqué: College of Humanities, Arts & Sciences Alumni Magazine

Contents:

EVERY ISSUE
Message from the Dean --- 4
Donor Feature --- 5
CHAS Briefs --- 36
Class Notes --- 38

FEATURES
Engineering Advances --- 6
Japan Water Quality Trip --- 10
Theatre Outreach --- 14
A Future in Physics --- 18
International Teaching --- 24

STORIES
SLP Community Partnership --- 22
Professional Readiness --- 28
Syndaver Lab --- 30
Art Teaching Sisters --- 32
Math Alum Now NBA Coach --- 34

Radiobiological And Dosimetric Comparison Of Imrt And Sbrt For Prostate Cancer Treatment Planning, Najmun Naher

Electronic Theses and Dissertations

Radiation therapy is one of the most effective and widely utilized methods for treating prostate cancer, employing high energy rays or particles to eradicate cancer cells. Among the available techniques, intensity-modulated radiation therapy (IMRT) and stereotactic body radiation therapy (SBRT) are commonly used approaches that enable the delivery of a conformal radiation dose to the target tumor while minimizing exposure to surrounding healthy tissues. This study presents a comparative analysis of these two treatment plans for prostate cancer based on radiobiological and dosimetric parameters. IMRT treatment plans for prostate cancer patients were collected, and corresponding SBRT plans were developed using …

Statistical Investigation Of Gypsum Crystallization Kinetics, Azmain A. Akash

LSU Master's Theses

Gypsum, a naturally occurring mineral salt, is frequently encountered in industrial processes such as seawater desalination and power plant cooling. Over the years, significant effort has been devoted to controlling the crystallization of gypsum through various chemical approaches, including acidification, chelating agents, and antiscalant polymers. Nevertheless, the cost associated with chemical treatments may be reduced by incorporating physical operational strategies to complement chemical methods in regulating gypsum crystallization.

This study systematically examines the comparative roles of chemical and physical entropy in the gypsum crystallization process to elucidate their respective influences on gypsum growth kinetics. Chemical entropy is manipulated by adjusting …

The Nesting Ecology Of Southern Two-Lined Salamanders (Eurycea Cirrigera) In Urban Streams, Leah T. Rittenburg, Emma G. Downing, Todd Pierson

Faculty Articles

Urbanization alters many aspects of stream ecosystems, and its effects upon wildlife will likely increase as more watersheds become developed. This may be particularly true for species with complex life histories, which could be vulnerable in different life stages. Eurycea cirrigera (Green) (Southern Two-lined Salamanders) are common members of many stream communities in the southeastern United States, and they prefer to nest in cobble with little sedimentation—a microhabitat that is threatened by stream degradation. We collected data on the nesting ecology of this amphibian species in urban streams in Atlanta, Georgia, to evaluate microhabitat availability, nest-site selection, and the influence …

Cross-Facility Reliable Deep Learning Based Beef Marbling Assessment Via Unsupervised Domain Adaptation Regression, Samuel Vinson, Dongyi Wang

2025 Research Poster Competition

Beef is one of the most important sources of animal protein and plays a crucial role in daily diets to support muscle growth, energy production and overall health. Historically, each beef carcass was evaluated by 3-5 skilled United States Department of Agriculture (USDA) meat graders, which are still considered as the gold standard for grading. Since 2009, electronic imaging grading systems have been approved by the USDA and have been gradually adopted in the grading facilities. Accurate and consistent beef grading plays a critical role in maintaining the quality, market value, and consumer trust in U.S. beef products. The USDA …

From Portraits To Bathwater: Desire, Imitation, And Violence In The Picture Of Dorian Gray And Saltburn, Kylie Marie Golden

All ETDs from UAB

This thesis examines the cycle of imitation within queer male desire in The Picture of Dorian Gray and Saltburn, arguing that both texts depict an unsustainable pattern in which protagonists mold themselves after an idealized other, leading to obsession, violence, and self-destruction. While Oscar Wilde’s novel encodes queerness within aestheticism and moral decay, Emerald Fennell’s film reconfigures these themes through class ambition and performative sexuality. I explore how both texts present imitation as a dangerous mechanism through which male characters construct their identities, only to find that their self-fashioning is ultimately untenable. This study positions Saltburn as a contemporary rewriting …