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Articles 44851 - 44880 of 818757
Full-Text Articles in Entire DC Network
Pygoscelis Penguins Prefer Different Oceanographic And Terrestrial Habitats During The Austral Summer, Katherine L. Gallagher, Rachel Herman, Katherine Walton, Michael S. Dinniman, Heather J. Lynch
Pygoscelis Penguins Prefer Different Oceanographic And Terrestrial Habitats During The Austral Summer, Katherine L. Gallagher, Rachel Herman, Katherine Walton, Michael S. Dinniman, Heather J. Lynch
OES Faculty Publications
Pygoscelis penguins interact with both terrestrial and marine environments, especially during the austral summer when they raise their chicks. Accessible ice-free ground spaces serve as locations for penguins to build colonies and successfully raise chicks while the surrounding marine environment serves as the foraging grounds for adult birds. Penguins must be able to navigate through the waters around their colonies to forage for Antarctic krill (Euphausia superba), their primary prey during the austral summer. Krill, whose distributions are driven partially by the surrounding physics and partially by their behaviors, must also be plentiful in the waters near the …
The Δ¹³C Signature Of Dissolved Organic And Inorganic Carbon Reveals Complex Carbon Transformations Within A Salt Marsh, Meagan J. Eagle, Kevin D. Kroeger, John W. Pohlman, Joseph J. Tamborski, Zhaohui Aleck Wang, T. W. Brooks, Jennifer O. Keefe Suttles, Adrian Mann
The Δ¹³C Signature Of Dissolved Organic And Inorganic Carbon Reveals Complex Carbon Transformations Within A Salt Marsh, Meagan J. Eagle, Kevin D. Kroeger, John W. Pohlman, Joseph J. Tamborski, Zhaohui Aleck Wang, T. W. Brooks, Jennifer O. Keefe Suttles, Adrian Mann
OES Faculty Publications
Coastal wetlands have high rates of atmospheric CO₂ uptake, which is subsequently respired back to the atmosphere, stored as organic matter within flooded, anoxic soils, or exported to the coastal ocean. Transformation of fixed carbon occurs through a variety of subsurface aerobic and anaerobic microbial processes, and results in a large inventory of dissolved carbon. Carbon source and the roles of aerobic respiration, sulfate reduction, and methane cycling were evaluated within salt marsh peat and the underlying sandy subterranean estuary. There is a large increase in dissolved inorganic carbon (DIC, 7,350 ± 3,900 μmol L-¹), dissolved organic carbon …
Dust Deposition To The Sargasso Sea: A Comparison Of Estimates Using Aluminum In The Surface Ocean Versus Aerosols And Rainwater, T. E. Williams, P. N. Sedwick, B. M. Sohst, K. N. Buck, S. Caprara, R. J. Johnson, D. C. Ohnemus, J. A. Resing, L. E. Sofen, A. Tagliabue, B. S. Twining
Dust Deposition To The Sargasso Sea: A Comparison Of Estimates Using Aluminum In The Surface Ocean Versus Aerosols And Rainwater, T. E. Williams, P. N. Sedwick, B. M. Sohst, K. N. Buck, S. Caprara, R. J. Johnson, D. C. Ohnemus, J. A. Resing, L. E. Sofen, A. Tagliabue, B. S. Twining
OES Faculty Publications
As a major component of mineral aerosol that partially dissolves in seawater, aluminum (Al) has been used to estimate time-averaged dust fluxes to the ocean, based on dissolved aluminum (DAl) concentrations and an assumed replacement time of DAl (tau DAl) in the surface mixed layer, along with the fractional solubility (Als) and mass abundance of Al in dust. We apply this method in the Bermuda region using seasonal water-column DAl concentrations, and compare our results with fluxes estimated from Al measured in Bermuda aerosols and rain. Inventories of DAl over the maximum mixed-layer depth of 200 m and empirically derived …
Characterization Of Microbial Biofilms On Marine Plastics: Community Development And Density Implications For Vertical Transport Dynamics, Gregory M. Joern, Rut Pedrosa-Pàmies, Xiangtao Jiang, Zhanfei Liu, Alexander B. Bochdansky
Characterization Of Microbial Biofilms On Marine Plastics: Community Development And Density Implications For Vertical Transport Dynamics, Gregory M. Joern, Rut Pedrosa-Pàmies, Xiangtao Jiang, Zhanfei Liu, Alexander B. Bochdansky
OES Faculty Publications
Marine plastic pollution poses a significant and escalating threat to ocean ecosystems, with microbial colonization on plastics playing a critical role in determining their environmental fate. Despite the recognized importance of microbial biofilms, their composition, dynamics, and functional contributions on buoyant plastics remain poorly understood. In this study, we leveraged a novel integrative approach by simultaneously employing 16S, 18S, and ITS sequencing alongside microscopy, lipidomics, pigment analysis, adenosine triphosphate and biogenic silica quantification. This comprehensive methodology allowed for a thorough characterization of microbial growth and community dynamics on plastic debris in a mid-latitude, tidal sub-estuary. Our analyses consistently identified diatoms, …
Traction Force Microscopy Using An Epifluorescence Microscope: Experimental Considerations And Caveats, Zaria Booth, Mazen Mezher, Rudra Patel, Venkat Maruthamuthu
Traction Force Microscopy Using An Epifluorescence Microscope: Experimental Considerations And Caveats, Zaria Booth, Mazen Mezher, Rudra Patel, Venkat Maruthamuthu
Mechanical & Aerospace Engineering Faculty Publications
Forces exerted by cells due to their internal contractility play fundamental roles in a host of processes, including adhesion, migration, survival and differentiation. Traction force microscopy (TFM) enables the determination of forces exerted by cells or cell collectives on their environment, which is typically taken to be an extra-cellular matrix (ECM)-coated substrate. Sample preparation for TFM involves the plating of cells onto an environment embedded with fiducial markers. The imaging of these fiducial markers in the presence and absence of the cells then enables calculation of the displacement of localized regions of the environment, and, consequently, the spatial distribution of …
Existence And Stability Of A Mathematical Model Solution Of Classical Brain Metabolite Variations In The Circadian Rhythm, Eman A. A. Ziada
Existence And Stability Of A Mathematical Model Solution Of Classical Brain Metabolite Variations In The Circadian Rhythm, Eman A. A. Ziada
Mansoura Engineering Journal
This research aims to study an important model in view of its applications to brain metabolite variations in the circadian rhythm. We will discuss the solution existence and stability of the general form of this model and give its solution by using numerical and analytical methods. The numerical method is the proposed numerical method (El- Sayed method), and two analytical methods, the Adomian decomposition method (ADM) and the Picard method (PM). The uniqueness of the solution will be proved, the convergence of the series solution will be discussed, and an error analysis will be given. The numerical solution of the …
Comparative Analysis Of Real-Time Fluorescence-Based Spectroscopic Instruments: Bioaerosol Detection In The Urban Environment Of Dublin City, Ireland, Jerry Hourihane Clancy, Emma Markey, Moisés Martínez-Bracero, Jose María Maya Manzano, Eoin Mcgillicuddy, Gavin Sewell, Roland Sarda-Estève, Dominique Baisnée, Andrés M. Vélez-Pereira, Gemma Davis, David J. O’Connor
Comparative Analysis Of Real-Time Fluorescence-Based Spectroscopic Instruments: Bioaerosol Detection In The Urban Environment Of Dublin City, Ireland, Jerry Hourihane Clancy, Emma Markey, Moisés Martínez-Bracero, Jose María Maya Manzano, Eoin Mcgillicuddy, Gavin Sewell, Roland Sarda-Estève, Dominique Baisnée, Andrés M. Vélez-Pereira, Gemma Davis, David J. O’Connor
Research Outputs: 2025-Present
No abstract provided.
Theoretical And Experimental Investigation Of Slanted Volume Transmission Gratings For Holographic Gas Sensing, Graceson Antony, Dervil Cody, Svetlana Mintova, Izabela Naydenova
Theoretical And Experimental Investigation Of Slanted Volume Transmission Gratings For Holographic Gas Sensing, Graceson Antony, Dervil Cody, Svetlana Mintova, Izabela Naydenova
Articles
Slanted photopolymer-based diffraction gratings can undergo instant and quantifiable analyte-induced changes in both grating diffraction efficiency and peak reconstruction wavelength. This makes them an attractive option for gas sensing applications. The underlying mechanism for the sensor response is, however, poorly understood due to its complexity; the gaseous analytes produce simultaneous changes in multiple grating parameters (refractive index, thickness, refractive index modulation, and slant angle). Here, a novel and robust approach to the experimental characterization and theoretical analysis of holographic gas sensors based on slanted volume transmission gratings is presented. Slanted transmission gratings were fabricated in both undoped and MFI nanozeolite-doped …
Transient Transmembrane-Electrostatically Localized Protons And Transmembrane Potential In A Laser Flashed Bacteriorhodopsin Purple Membrane Open Flat Sheet - Summary, James Weifu Lee
Chemistry & Biochemistry Faculty Publications
The transmembrane-electrostatically localized protons/cations charges (TELCs, also known as TELPs) model may serve as a unified framework to explain a wide range of bioenergetic phenomena. Transient transmembrane-electrostatically localized protons (TELPs) and transmembrane potential in a laser flash-energized bacteriorhodopsin (bR) purple membrane (PM) open flat sheet are now better analyzed. Under the Heberle et al. (1994) experimental conditions, the number of bR molecules is now calculated to be 8200 per PM open flat sheet with a diameter of 600 nm. With a single-turnover laser flash intensity of 3 mJ/cm² to photoexcite 10% of the bR molecules, the laser flash-induced peak TELCs …
Are There Predictable Shifts In Fish Communities Following Instream Habitat Restoration? A Multistream Analysis., Ryan A. Skowronski
Are There Predictable Shifts In Fish Communities Following Instream Habitat Restoration? A Multistream Analysis., Ryan A. Skowronski
Masters Theses
In the past two centuries, anthropogenic stressors have degraded the structure and function of streams by accelerating bank erosion, decreasing riparian buffer zones, and altering the natural flow regime. Habitat restoration has become a common mitigation strategy in response to stream degradation, though empirical research evaluating its effectiveness is lacking in the United States. This study investigated responses in fish community following habitat restoration in five restored, Illinois streams. We assigned fish species to habitat, trophic, and reproductive guilds based on their habitat preferences, feeding habits, and life history. Streams were separated into enhancement and removal groups for analysis. Shifts …
Parasite Communities Of Bluntnose Minnow (Pimephales Notatus) From Several Creeks In East Central Illinois, Md Rowshan Alam
Parasite Communities Of Bluntnose Minnow (Pimephales Notatus) From Several Creeks In East Central Illinois, Md Rowshan Alam
Masters Theses
Parasites of freshwater fish play a vital functional role in aquatic ecosystems, but the spatial and ecological determinants of their prevalence and characteristics are still poorly understood. The current study quantified the diversity, prevalence, and environmental determinants of whole parasite burdens in bluntnose minnows across multiple creeks in central Illinois. Fish sampling and the collection of stream habitat data were conducted during the summers of 2023 and 2024. Fish were examined for parasites using necropsy and histology. A total of 20,817 parasites, predominantly trematodes (Posthodiplostomum spp.), cestodes (Proteocephalus spp), and protozoans, were identified. The most prevalent and abundant …
Assessing The Role Of Daily Thermal Fluctuations In The Performance Of Mitochondrial Energy Transduction Of The Centrarchid, Lepomis Cyanellus, Grayson Hofmann
Assessing The Role Of Daily Thermal Fluctuations In The Performance Of Mitochondrial Energy Transduction Of The Centrarchid, Lepomis Cyanellus, Grayson Hofmann
Masters Theses
Freshwater systems are affected by current climate extremes, forcing species found in these systems to withstand drastic changes in temperature. Temperature changes affect these organisms by altering their metabolic rate and energy balance. Increases in temperature can lead to an increase in oxygen consumption, which ultimately increases the need for more energy production. Mitochondrial energy transduction of green sunfish (Lepomis cyanellus) and many other fish species after a thermal insult, has hardly been explored. This study complements the limited research available on mitochondrial function in similar species, as they ignore the possibility of consecutive thermal events, which are …
The Relationships Of Anxiety Sensitivity, Intolerance Of Uncertainty, And Alexithymia On University Students’ Experiences Of Depression, Anxiety, And Stress, Vanessa Watterson
The Relationships Of Anxiety Sensitivity, Intolerance Of Uncertainty, And Alexithymia On University Students’ Experiences Of Depression, Anxiety, And Stress, Vanessa Watterson
Masters Theses
Undergraduates’ mental health has seen a significant decline over the past several decades. Past research has identified significant correlations between specific cognitive vulnerabilities and experiences of psychological distress. The current study reviewed the literature on relationships between three cognitive vulnerabilities (anxiety sensitivity, intolerance of uncertainty, and alexithymia) and individuals’ experiences of depression, anxiety, and stress. Further, this study utilized a hierarchical regression model to examine the predictive abilities of anxiety sensitivity, intolerance of uncertainty, and alexithymia on depression, anxiety, and stress, respectively. The findings indicated that all three cognitive vulnerabilities had significant and unique contributions to depression, anxiety, and stress …
Experiences Of Qpoc College Students: The Complexities Of Navigating Multiple Minoritized Identities, Attainea S. Toulon
Experiences Of Qpoc College Students: The Complexities Of Navigating Multiple Minoritized Identities, Attainea S. Toulon
Masters Theses
Queer People of Color (QPOC) experience unique challenges within higher education as they navigate the intersections of race, sexuality, and gender at predominantly White institutions (PWIs). This qualitative narrative study explored the lived experiences of three QPOC college students at a mid-sized public university in the Midwest. Through semi-structured interviews, participants shared how their intersecting identities shaped their sense of belonging, access to support systems, and overall university experiences. Findings revealed that while participants found affirmation through cultural organizations, staff mentors, and chosen family, they also encountered racialized exclusion within LGBTQ+ spaces and heteronormative expectations within racialized spaces.The narratives illustrated …
Disease Diagnosis Using Natural Language Processing And Deep Learning, Manas Kumar Sherla
Disease Diagnosis Using Natural Language Processing And Deep Learning, Manas Kumar Sherla
Masters Theses
This research presents an automated disease diagnosis framework that leverages natural language processing and deep learning to predict diagnosis codes from unstructured electronic health record (EHR) clinical notes. Using the MIMIC-III critical care dataset, clinical narratives such as discharge summaries and physician notes are extracted, validated, and preprocessed to construct a labeled corpus aligned with ICD-9 diagnoses. The study implements a pipeline comprising text cleaning, feature extraction, and supervised learning, and compares traditional models such as Logistic Regression and Bi-LSTM with transformer-based architectures built on BERT. Models are trained and evaluated with categorical cross-entropy loss and standard multi-class metrics, including …
The Impact Of Artificial Intelligence On College Sport Communications, Will Barnhart
The Impact Of Artificial Intelligence On College Sport Communications, Will Barnhart
Masters Theses
As Artificial Intelligence technology (AI) becomes increasingly accessible, the importance of understanding its impact on peoples’ work lives is also increasing. One field that has received very little attention in relation to this subject is college sport communications. Prior research has focused on AI within the closely related fields of journalism and public relations, but no previous studies have been conducted on AI and college sport communicators specifically. To address that knowledge gap, this study surveyed members of the College Sport Communicators (CSC) on their attitudes toward AI and their usage of such technology. The data analysis showed that while …
Childhood Maltreatment And Social Anxiety In College Students: Examining The Role Of Distress Tolerance, Alexa N. Matthies
Childhood Maltreatment And Social Anxiety In College Students: Examining The Role Of Distress Tolerance, Alexa N. Matthies
Masters Theses
This study examines the relationship between childhood emotional maltreatment and social anxiety, with a focus on the mediating role of distress tolerance. Emotional maltreatment has been linked to numerous adverse psychological outcomes, yet its specific contribution to social anxiety symptoms requires further exploration. Using a sample of 94 participants aged 18 to 24, this research employs validated instruments, including the Childhood Trauma Questionnaire and Liebowitz Social Anxiety Scale, to assess the prevalence and impacts of emotional abuse and neglect. Findings reveal significant correlations between emotional abuse, neglect, and elevated social anxiety symptoms. Distress tolerance emerged as a key mediator, partially …
Habitat Use And Selection Of Silver Carp In The Lower Wabash River System, Coy B. Blair
Habitat Use And Selection Of Silver Carp In The Lower Wabash River System, Coy B. Blair
Masters Theses
The spatial ecology of non-native species in invaded systems remains relatively poorly understood despite the importance of suitable habitat in the success of invasion. Silver Carp Hypophthalmichthys molitrix are a highly invasive non-native species with established populations throughout the Midwestern United States. Much research has focused on habitat use of bigheaded carp in large river systems, though invasion risk remains high in smaller systems, such as tributaries of the Great Lakes and the Ohio River. The Wabash River, a unique system in the Midwest, remains largely un-impounded and is comparable to many of the smaller riverine systems at risk of …
Domestic Student Engagement With International Peers: Local Insights, Global Connections, Alissa Sutton
Domestic Student Engagement With International Peers: Local Insights, Global Connections, Alissa Sutton
Masters Theses
As competition to recruit international students grows, institutions must prioritize fostering a sense of belonging that supports their retention and success. Central to this is the quality of interactions between international and domestic students, which shape both groups’ social and academic experiences. This study examines the barriers and facilitators influencing domestic students’ engagement with international peers and the role of institutional support in promoting meaningful cross-cultural connections. Findings reveal that domestic students recognize the importance of engaging with international peers but they often encounter challenges such as lack of awareness, uncertainty about how to connect, and limited institutional opportunities. Support …
Women Spinning On The Edge: Finding And Redefining The “Spinster” In The Witches Of Discworld, Kathryn Ann Fitzmaurice
Women Spinning On The Edge: Finding And Redefining The “Spinster” In The Witches Of Discworld, Kathryn Ann Fitzmaurice
Masters Theses
The word “spinster” has undergone a series of evolutions over the past seven hundred years, first coined to describe the occupation of women engaged in the spinning of plant and animal fibers into thread and yarn in the Middle Ages and later a legal marital status designation used until the 21st century. The connotation associated in social contexts became pejorative. This project’s tracing of the word spinster is used to set up the broader scope looking at how the spinster can be viewed as an archetype, what we can learn through the lenses of gender and feminist theory, and …
The Influence Of Family-School Communication On Junior High School Students’ Academic Success, Stephen Junior Amoah
The Influence Of Family-School Communication On Junior High School Students’ Academic Success, Stephen Junior Amoah
Masters Theses
This study examines the influence of family-school communication on students' academic success in the context of Ghana, with a particular focus on Junior High School (JHS) students. While existing research emphasizes the importance of family involvement in educational outcomes, limited studies explore how family-school communication directly affects academic success in Ghana. By using a mixed-methods approach, the study combines quantitative and qualitative data collection. The quantitative component includes an online survey distributed to JHS graduates, assessing the frequency, impact, methods, and barriers of communication between families and schools, as well as their perceived effect on academic performance. The survey includes …
Chronic Sleep Fragmentation Differentially Affects Alzheimer’S Disease Pathology In Male And Female AppSaa Knock-In Mice, Margaret R. Hawkins, Haleigh R. Whitlock, Carrie E. Johnson, Teresa Macheda, Ma Kayla F. Cox, Madison G. Lapid, Kelly N. Roberts, Heather M. Hash, Esther G. Drinkard, Sridhar Sunderam, Bruce F. O’Hara, Michael P. Murphy, Marilyn J. Duncan, Adam D. Bachstetter
Chronic Sleep Fragmentation Differentially Affects Alzheimer’S Disease Pathology In Male And Female AppSaa Knock-In Mice, Margaret R. Hawkins, Haleigh R. Whitlock, Carrie E. Johnson, Teresa Macheda, Ma Kayla F. Cox, Madison G. Lapid, Kelly N. Roberts, Heather M. Hash, Esther G. Drinkard, Sridhar Sunderam, Bruce F. O’Hara, Michael P. Murphy, Marilyn J. Duncan, Adam D. Bachstetter
Biology Faculty Publications
Introduction: Sleep fragmentation often precedes Alzheimer’s disease (AD) diagnosis and represents a potential modifiable risk factor, especially among women who have higher prevalence of both sleep disorders and AD. Methods: This study investigated how chronic sleep fragmentation affects neuroinflammation and amyloid-beta (Aβ) accumulation in male and female APPSAA knock-in mice, a physiologically relevant AD model expressing APP at normal levels. APPSAA mice of both sexes (N=8/sex/strain, 8 months old) underwent either 5 weeks of chronic sleep fragmentation administered during the light phase using an automated sweeper system or undisturbed sleep. Sleep-wake patterns and circadian rhythms were monitored using …
Simpson's Tachytely Or Bradytely? The Importance Of Quantifying Rate Uncertainty, Rosana Zenil-Ferguson, Lee Hsiang Liow
Simpson's Tachytely Or Bradytely? The Importance Of Quantifying Rate Uncertainty, Rosana Zenil-Ferguson, Lee Hsiang Liow
Biology Faculty Publications
The spectacular variation in species forms and richness across space and time can be explored using sophisticated and powerful tools recently developed by evolutionary modellers. In this contribution, we ask if the classic ‘Simpsonian’ view of tachytelic (fast), horotelic (standard) and bradytelic (slow) diversification rates can be distinguished with currently available tools and data. A neglected topic here is the role that the uncertainty of diversification rate estimates plays, where the lack of in-depth uncertainty measures could hinder our ability to confidently suggest differences in speciation or extinction rates in any given comparison. We propose quantifying the relative uncertainty of …
“I Just Don’T Find It Interesting”, Jennifer L. Osterhage, Utku Caybas, Jaeyun Han, Ellen L. Usher
“I Just Don’T Find It Interesting”, Jennifer L. Osterhage, Utku Caybas, Jaeyun Han, Ellen L. Usher
Biology Faculty Publications
Situated expectancy-value theory (SEVT) posits that students’ expectancies for success, task values, and perceived costs affect their performance in STEM courses. Less is known about how students’ majors and timing of course completion affect motivational processes. Using the SEVT framework, this study utilised a convergent mixed methods approach to investigate academic motivation among students (N = 646) who enrolled in introductory biology at a large public university. Survey data revealed that students majoring in Biology were more motivated than students from other majors, although academic major was not directly associated with final grade. Upper-level students reported significantly lower competence-related beliefs …
Seasonal Divergence In Reproductive Timing On The Verge Of Spring, Devraj Singh, Adam M. Fudickar, Ellen D. Ketterson
Seasonal Divergence In Reproductive Timing On The Verge Of Spring, Devraj Singh, Adam M. Fudickar, Ellen D. Ketterson
Biology Faculty Publications
Every year as spring approaches and day length increases, many birds begin to reproduce, an annual expression of seasonal phenology that requires physiological preparation. In species distributed over a broad geographic range, populations that breed at higher latitudes are often migratory and delay reproduction until later in the year as compared to those breeding at lower latitudes. Dark-eyed Juncos serve as an excellent model for understanding the timing mechanisms regulating population-level variation in seasonal reproductive responses. We compared two seasonally sympatric dark-eyed junco populations in early spring. One migrates (Junco hyemalis hyemalis) and breeds in Alaska and Canada, while the …
Chromatin Remodeling Protein Bptf Mediates Chromatin Accessibility At Gene Promoters In Planarian Stem Cells, Prince Verma, John M. Allen, Alejandro Sánchez Alvarado, Elizabeth M. Duncan
Chromatin Remodeling Protein Bptf Mediates Chromatin Accessibility At Gene Promoters In Planarian Stem Cells, Prince Verma, John M. Allen, Alejandro Sánchez Alvarado, Elizabeth M. Duncan
Biology Faculty Publications
Background The regulation of chromatin accessibility is essential in eukaryotic cells as one of several mechanisms that ensure gene activation occurs at appropriate times and in appropriate cell types. Accordingly, mutations in chromatin remodeling proteins are linked to many different developmental disorders and cancers. One example of a chromatin protein that has been linked to both developmental abnormalities and cancer is BPTF/NURF301, the largest subunit of the Nucleosome Remodeling Factor (NuRF) complex. The BPTF subunit is not only important for the formation of NuRF but also helps direct its activity to particular regions of chromatin by preferentially binding histone H3 …
Unraveling Silence, Precious Gyekye
Unraveling Silence, Precious Gyekye
School of Art Graduate Exhibitions, Portfolios, and Theses
No abstract provided.
Assessing Electronic Nicotine Delivery System Abuse Liability Among People Who Smoke Cigarettes: Impact Of Device Characteristics, Nicotine Flux, And Flavor, Elizabeth Oluwapelumi Ogunleye
Assessing Electronic Nicotine Delivery System Abuse Liability Among People Who Smoke Cigarettes: Impact Of Device Characteristics, Nicotine Flux, And Flavor, Elizabeth Oluwapelumi Ogunleye
Theses and Dissertations
This clinical laboratory study utilizes subjective and behavioral economic measures to assess the abuse liability of own-brand cigarettes and six currently authorized ENDS products, examining how device characteristics, nicotine flux, and liquid flavor influence outcomes among adults who smoke cigarettes. Using a Latin-square-ordered, within-subject design, adults who smoke cigarettes (N = 30; N = 20 preferred menthol cigarettes) attended four clinical sessions: one to evaluate their own-brand cigarette and three to assess six NJOY ENDS products: 2.4% nicotine pods (~58 µg/s; tobacco and menthol flavor), 6% nicotine disposable products (~61-65 µg/s; tobacco and menthol flavor), and 5% nicotine pods (~118-123 …
Acute Effects Of Electronic Nicotine Delivery System Liquid Nicotine Form And Sweetener Among People Who Use Inhaled Tobacco Products, Mary A. Carrico
Acute Effects Of Electronic Nicotine Delivery System Liquid Nicotine Form And Sweetener Among People Who Use Inhaled Tobacco Products, Mary A. Carrico
Theses and Dissertations
Research on tobacco product standards to limit the abuse liability of electronic nicotine delivery systems (ENDS) has primarily focused on nicotine concentration and flavor. Other liquid characteristics, such as protonated nicotine ratio and sweetener additives, are less understood but may serve as regulatory targets. This clinical laboratory study examined the effects of ENDS protonated nicotine ratio and sweetener presence on nicotine delivery, use behavior, and subjective effects.
Thirteen participants completed four sessions that varied by protonated nicotine ratio (0:100 vs. 40:60 freebase to monoprotonated nicotine) and sweetener status (sweetened with 3 mg/mL ethyl maltol vs. unsweetened). Each session included a …
Doves And Symbiotic Bacteria: Whole-Genome Assembly And Phylogenomic Inference, Mariam Topchyan
Doves And Symbiotic Bacteria: Whole-Genome Assembly And Phylogenomic Inference, Mariam Topchyan
Theses and Dissertations
Part 1
I examined a potential source of variation in phylogenetic inference, investigating whether handling single-nucleotide polymorphisms (SNPs) through different methods during reference-guided genome assembly of pigeon and dove species impacts phylogenetic reconstruction and inference. Specifically, I created a custom consensus base calling tool that handles allelic variation through two different approaches, either ignoring heterozygous sites by denoting them as an ambiguous character “N,” or using a pseudo-random choice between supported base variants. Through reference-guided assembly of 108 dove species, I generated two datasets of alignments using both consensus calling methods, created two trees from both datasets via supermatrix and …