Digital Commons Network^™

2025-02-19 Seattle U Students Survive Another Quarter Of Midterms, Dylan Berman

The Spectator Online

No abstract provided.

February 19, 2025 (Vol. 109, No. 19), Daily Eastern News

Daily Eastern News: 2024-2025

No abstract provided.

Zno Nanowires For Biosensing Applications, G.M. Mehedi Hossain, Daniel Garza, Emilio Chavez, Ahmed Hasnain Jalal, Fahmida Alam

Electrical and Computer Engineering Faculty Publications

Zinc oxide Nanowires (ZnO-NWs) are promising biosensor materials and hold the key to overcoming challenges in the field. This chapter provides an introductory overview of biosensing technology, focusing on the fundamental principles and comparing ZnO-NWs with other nanostructures regarding the surface area, reactivity, electrical properties, charge transport behavior, optical, magnetic, and piezoelectric properties, and mechanical flexibility. Providing the synthesis and characterization methods, ZnO-NWs’ biosensing processes are also elaborated on surface modification for selectivity, integration with microfluidic systems, enhancing signal transduction, and connecting with biological elements like enzymes, antibodies, and DNA. The chapter also discusses the applications of ZnO-NWs-based biosensors in …

Therapy Combining Sorafenib And Natural Killer Cells For Hepatocellular Carcinoma: Insights From Magnetic Resonance Imaging And Histological Analyses, Zigeng Zhang, Guangbo Yu, Aydin Eresen, Qiaoming Hou, Sha Webster, Farideh Amirrad, Surya M. Nauli, Zhuoli Zhang

Pharmacy Faculty Articles and Research

Background/Objectives: Hepatocellular carcinoma (HCC) remains a significant global health issue due to its high mortality rate and resistance to standard treatments. Sorafenib, the first-line systemic therapy for unresectable HCC, shows limited effectiveness due to resistance and severe side effects. Recent studies suggest that combining sorafenib with immunotherapy, particularly natural killer (NK) cells, may improve treatment outcomes. Methods: This study examined the effectiveness of sorafenib combined with NK cells pretreated with interleukin-12 (IL-12) and interleukin-18 (IL-18) in a rat HCC model. Tumor progression and treatment outcomes were assessed using MRI and histological analysis. Results: The results show that …

Study To Understand The Effects Of Biofouling And Corrosion On Underwater Munitions: Implications For Risk Management And Resource Allocation, Center For International Stabilization And Recovery, Fenix Insight

Global CWD Repository

The project's primary objective is to understand the impacts of the underwater environment on munitions as a means to identify the residual risk these munitions pose, so people undertaking detection and clearance efforts can reliably assess operational risk and make informed decisions.

Phylogenetic Allometric Scaling Of Near Basal Breathing Frequency In Terrestrial, Semi-Aquatic And Aquatic Mammals, Andreas Fahlman, Elliot Stielstra, Ethan Wilstermann, Simon Rylaarsdam, Josefin Larsson, Guillermo J. Sanchez -Contreras, Suguru Higa, Gonçalo N. Marques, Malgosia Kaczmarska, Jason Somarelli, Stacy L. De Ruiter

University Faculty Publications and Creative Works

We measured the BASAL breathing frequency following an overnight fast in adult,non-pregnant/non-lactating, inactive mammals ranging in body mass from 15 to5520 kg. The data included results from 338 individual animals from 34 speciesthat were divided into terrestrial, semi-aquatic (Otariidae and Phocidae) and aquaticmammals. Following attempts to limit the collection of breathing frequency usinga basal definition and to correct the analysis phylogenetically, our results suggestthat there are differences in the allometric mass-exponent between terrestrial andaquatic/semi-aquatic mammals. An allometric regression model, whereby both bodymass and breathing frequency were transformed using log10 , suggested that theallometric mass exponent for terrestrial mammals (−0.303) was …

Multiple Hypothesis Testing Under Dependence, Nabaneet Das

Doctoral Theses

We have examined various aspects of multiple hypothesis testing under dependence. Traditional algorithms designed to control the error arising from multiplicity become severely conservative when the hypotheses exhibit positive dependence, resulting in a loss of power. There is a paucity of literature explicating the behaviour of traditional algorithms when the hypotheses are dependent. In the realm of multiple testing, a popular multiplicity correction is the Bonferroni correction, which is perhaps the oldest classical approach for controlling the Family-Wise Error Rate (FWER) at a desired level, regardless of dependence among hypotheses. However, under the global null and equicorrelated normal model, the …

Correlation Of Gnas Mutational Status With Oncologic Outcomes In Patients With Resected Intraductal Papillary Mucinous Neoplasms, Julia S. Evans, Kylee Shivok, Hui Hsuan Chen, Eliyahu Gorgov, Wilbur Bowne, Aditi Jain, Phd, Harish Lavu, Charles J. Yeo, Avinoam Nevler

SKMC Student Presentations and Publications

Background: Intraductal papillary mucinous neoplasms (IPMNs) are pre-malignant pancreatic lesions that may progress to invasive pancreatic ductal adenocarcinoma (PDAC). IPMN-associated invasive carcinoma (iIPMN) has been associated with more favorable survival outcomes compared to non-iIPMN-derived PDAC. Here, we aim to investigate the genetic landscape of IPMNs to assess their relevance to oncologic outcomes. Methods: This retrospective study used a large single-institution prospectively maintained database. Patients who underwent curative-intent pancreatic resection between 2016 and 2022 with histologically confirmed diagnosis of IPMN were included. Demographic, pathologic, molecular, and oncologic outcome data were recorded. Kaplan–Meier survival analyses were performed. PDAC data from public genetic …

A Bibliometric Study Of Astronomy And Geoscience Doctoral Dissertations, Nora Boyle, Mary Schlembach

Faculty Journal Articles

A bibliometric analysis was conducted over the bibliographies of astronomy and geology doctoral dissertations written between 1970 and 2020 in order to review the document types that are utilized and cited. An investigation was made of various cited reference ages and how cited references in dissertations have evolved with the advent of electronic resources and preprint services. Our study examined 50 astronomy and 50 geology dissertations with 10 dissertations selected from each decade (n = 100). Results measured included 13,475 total references and the study found that references to journal articles increased, and book citations have decreased in both …

Aging Is Associated With Decreased Lactobacillus And Increased Cervicovaginal Inflammation In Canadian Women, Ha T. Dang, Laura Noel-Romas, Samantha Knodel, Kenzie Birse, Hossaena Ayele, Alicia R. Berard, Adam D. Burgener, Christina Farr Zuend

Faculty Scholarship

Problem: Aging is characterized by a general dysregulation of systemic immune responses that increases susceptibility to infections and malignancies. Immune cells in the female genital tract (FGT) are regulated by sex hormones, but little is known about the impact of aging and menopause on immunology in the FGT. Method of Study: This study conducted an age-focused sub-analysis of cervicovaginal samples collected from 47 women enrolled in the Vaginal Mucosal Systems study in Winnipeg, Canada. Paired cervicovaginal lavage and cervical cytobrush were collected and analyzed by Luminex cytokine array, mass spectrometry based metaproteomics, metabolomics, and high dimensional flow cytometry. Results: The …

Meet The Spring '25 Climate Action Clinic Cohort, Sustainability Institute

Sustainability Institute Blog

No abstract provided.

The Legal Framework Of Foster Care In Egypt: A Gender Analysis Of Alternative Families And Patrilineal Structures, Amira Fadel

Theses and Dissertations

The thesis explores women’s legal representation and agency over their non-biological children, and how the foster care system in Egypt either reinforces or deconstructs existing gender roles. Hence from a sociological perspective, it accounts for foster and alternative care laws in Egypt and the amendments thereof, to examine social relationships against the backdrop of more conventional, biological families, and kinship relations. In simple terms, studying foster and alternative care laws in Egypt is crucial to grasp how non-biological families are shaped in comparison to the more conventional bonds within biological families and traditional kinship relations, while accounting for the Christian …

The Metaphysics Of Time Within Physics, Mohamed Ahmed

Theses and Dissertations

The starting point of this thesis is to shed some light on the metaphysical nature of time by reflecting on the physics of time. The aim of this approach is not to [dis]prove or defend a metaphysical position but rather to elucidate the metaphysical position that underlies [or is compatible with] our best scientific theories. This task will be demanding, not only because our best theories may carry different interpretations of their underlying temporal structure but also because there seems to be a conceptual conflict/incompatibility between the notion of time in relativity and quantum mechanics, which are the two major …

The Role Of Non-Coding Rnas As An Innovative Therapeutic Tool For Hepatocellular Carcinoma, Nabila Mohamed Hosni El Kramani

Theses and Dissertations

Hepatocellular carcinoma (HCC) is the second lethal cancer worldwide, with over 60 million new patients added annually. Hepatitis B infection and toxins, e.g., aflatoxin, contribute to the incidence of HCC. Egypt and China show the highest prevalence of viral hepatitis and HCC in the world.

Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts larger than 200 nucleotides. These transcripts work at the transcriptional, post-transcriptional, and epigenetic levels to regulate gene expression by interacting with various biomolecules, such as RNA, DNA, and proteins. They serve essential functions in chromatin remodeling and cell survival, differentiation, and proliferation. The role and biological interactions of …

Predicting The Indirect Cost Of Construction Projects In Egypt: An Artificial Neural Network Approach, Aya Effat

Theses and Dissertations

Cost estimation is one of the vital processes in construction management that needs to be done early in any project in order to determine the project's budget. The accuracy of the cost estimate is a key factor in the success of construction projects since it enables project managers to successfully control the project’s expenses. Construction costs mainly consist of direct cost and indirect cost. Generally, indirect costs can be categorized into two types: site overheads and general overheads. In a construction project, overheads, particularly site overhead costs, make up a considerable portion of a contractor's budget. Accordingly, accurately estimating the …

Identification Of Novel Genetic Biomarkers Linked To The Prodromal Stage Of Parkinson’S Disease (Pd) Patients, Marwa Tawfik Badawy

Theses and Dissertations

Background and Objective: The early diagnosis of neurodegenerative diseases, such as Parkinson's disease (PD), is particularly challenging because symptoms appear only after significant neuronal damage has already occurred. This study is utilizing variant call format (VCF) analysis to identify genetic variants and novel genes that could serve as early prognostic markers for prodromal PD. Materials and Methods: Data were sourced from the Parkinson's Progression Markers Initiative (PPMI), focusing on prodromal patients with gVCF data from the 2021 cohort. The study included 304 participants, comprising 100 healthy controls, 146 individuals with prodromal genetic indicators, 21 individuals with prodromal hyposmia, and 37 …

Integrating Planetary Health Into Public Health Education For Sustainable Healthcare Practices, Eman Aboualy

Theses and Dissertations

Introduction: Integrating planetary health in public health education became an urgent global call for action since the WHO announced that the climate change and environmental degradation are the most threat facing the humanity in the recent decades (1). According to that, many countries are developing strategies for counteracting and mitigating the impact of climate change and restore the planetary health. These strategies are including policy drafting and preparing their public health professionals to recognize and address the health effects of environmental change, promote practices for sustainable healthcare. Although Egypt is formulating different policies to cope with and respond to the …

Factors In Teacher Turnover Within A Nonpublic Special Education Setting, Sarah Wilson

Walden Dissertations and Doctoral Studies

The persistent turnover among special educators poses significant challenges to the quality of education provided to students with disabilities. The problem addressed in this study was the significant rate of turnover of special education teachers in a nonpublic special needs school on the east coast of the United States. Guided by Maslow’s theory of motivation and hierarchy of needs, the purpose of this basic qualitative study was to investigate the experiences of special education teachers and factors that influenced their decision to remain within the classroom environment. Eight special educators participated in semistructured interviews sharing the experiences they perceived as …

Identification Of Novel Argonaute Proteins Using A Metagenomic Mining Approach, Lobna Abdallah Ghonaim

Theses and Dissertations

Gene editing is one of the most promising tools in science. It enables precise modifications of an organism's genetic material. Metagenomics is considered a powerful tool that unlocks the broad genetic potential found in uncultured microbial communities. Exploring the genetic diversity of uncultured microbial communities helps identify novel functional proteins with unique properties and make the best use of these diverse microbial ecosystems.

We developed and employed a metagenomic-based approach to mine more than 1000 metagenomes for prokaryotic argonaute proteins (pAgos), a potential gene editing machinery encoded in bacterial and archaeal genomes. Our workflow involved strict quality control, sequence assembly, …

Using Ai-Generated Scenarios To Enhance Learning Of The Emergency Assessment Process, D Cobble, L Schroeder, J Vaughn, S Ford

Clinical Practice in Athletic Training

Introduction: Rigorous accreditation standards require students to demonstrate competency in various clinical proficiencies through clinical practice or simulation-based educational activities. Therefore, simulation has become an integral component of athletic training education, as scenarios can provide realistic and reproducible experiences for all students. To that end, our study had two primary objectives: investigate the ability of artificial intelligence (AI) to generate accurate and realistic athletic training simulation scenarios and evaluate AI's effectiveness in teaching and reinforcing the emergency assessment process through student-created scenarios. Methods: Phase one, AI developed three different scenarios for patients experiencing (1) an ovarian cyst, (2) a hypoglycemic …

Prevalence, Perceptions, And Attitudes Of Accommodation For Students With Disabilities In Athletic Training Education Programs, T J. Babcock, L E. Eberman

Clinical Practice in Athletic Training

Introduction: Disability accommodation has been widely researched in healthcare education programs, including medical doctor (MD), doctor of osteopathy (DO), and physical therapy (PT). However, little research has been conducted on classroom and clinical education accommodation in athletic training education. The purpose of this study was to explore these settings and gain an understanding of student experiences with accommodation in athletic training education programs. This project was deemed exempt by Indiana State University’s Institutional Review Board. Methods: A cross-sectional 24-question survey was developed and adapted from prior qualitative research on accommodation in physical therapy education. Emails containing a link to the …

Effect Of Multispecies Swards On The Fat Composition And Oxidative Stability Of Milk From Dairy Cows In Mid-Late Lactation, Samuel Rapisarda, Kate M. Mccarthy, Tommy M. Boland, Helen Sheridan, Frank J. Monahan, Finbar J. Mulligan, Graham O'Neill, Nissreen Abu-Ghannam

Articles

Multispecies swards have been recognized as more sustainable than traditional ryegrass systems, in addition to providing a range of phytochemicals to the ruminant diet. In this regard, polyphenols may be linked to higher levels of bioactive fatty acids in milk and enhanced nutraceutical properties in dairy products. This study compares the fat composition and oxidative stability of milk produced by cows fed on multispecies swards (MULTI) with milk from two conventional swards [a perennial ryegrass monoculture (PRG) and a mixture of perennial ryegrass and white clover (PRG + WC)] during the Irish summer. Milk from cows fed on MULTI had …

Clinat: In Service To Athletic Training Scholarship, Lindsey Eberman, Matthew J. Rivera

Clinical Practice in Athletic Training

To be of service to others means to help others without expecting anything in return. The ClinAT, or Clinical Practice in Athletic Training journal, is an online, open-access outlet for the dissemination of practice-based research in health care, and a donation of time, effort, and energy to the profession of athletic training. In 2018, when Indiana State University created its first issue of ClinAT, we were a faculty of 3 with 5 PhD students supporting the journal, one of whom was wholly dedicated to the effort. As the higher education landscape has changed, and the roles and responsibilities of our …

Barriers To The Implementation Of The Amsterdam 2022 Statement In The Secondary School Setting, L Torres, J L. Baldari, F A. Gardin, A M. Price

Clinical Practice in Athletic Training

Introduction: The Amsterdam 2022 International Consensus Statement on Concussion in Sport provides a summary of contemporary best practice recommendations for healthcare providers who are involved in the care of athletes at risk of sport-related concussion (SRC). Given that athletic trainers (ATs) have a professional responsibility to continually educate themselves on topics of great importance to the population that they care for, such as SRC management, it is reasonable to expect them to evolve their concussion management protocols to better align themselves with the recommendations found this statement. The purpose of this study was to identify the barriers associated with the …

Exploring The Vitality Of Athletic Training: Insights Into Professional Identity, Commitment, And Retention, L E. Eberman, M J. Rivera, K E. Games, M J. Drescher, J P. Young, J Clifton-Gaw, K Condrey, H Mccarn, N Mondelli, X Yuan

Clinical Practice in Athletic Training

Introduction: The confluence of fluctuating retention, fewer students entering professional programs, and the profession’s identity crisis (conflict between being a sports profession or a health profession) has created a serious question about the vitality of the athletic profession. However, research on the vitality of the profession has often focused on singular variables influencing professional identity, burnout, and commitment. The purpose of this project was to explore multiple factors influencing the vitality of the profession across professional identity and commitment in athletic training. Methods: We used a convergent parallel mixed-methods design, including surveys and interviews with athletic training students and athletic …

Escape From Diabetes, J E. Jochum, J Carmack, J Toon

Clinical Practice in Athletic Training

Introduction: In the past decade, interprofessional education (IPE) to promote interprofessional collaborative practice has become an integral component of pre-licensure education in the health professions. Research shows that IPE activities involving problem-solving in patient care that requires cooperation and communication among the professions is most effective. An effective activity to meet interprofessional competencies is the use of escape rooms. Escape rooms are team-based games where groups of individuals solve puzzles to accomplish a specific goal, typically in a limited amount of time. There are many benefits to using escape rooms in education, including promoting problem-solving, teamwork, and creativity, improving focus …

Athletic Trainer Compensation Characteristics, J P. Young, K Ef Mair, L E. Eberman

Clinical Practice in Athletic Training

Introduction: Athletic trainers (ATs) are integral to healthcare yet face ongoing challenges that affect job satisfaction and retention. Factors such as long work hours, low pay, and work-family conflict contribute to dissatisfaction and a desire to leave the profession. Salary disparities and lack of administrative support are key factors impacting professional fulfillment and career longevity. Identifying how compensation influences job satisfaction is essential for improving retention and advancing the profession. Our study aimed to examine the compensation characteristics of ATs and determine the key factors that predict gross income. Methods: A cross-sectional, web-based survey was conducted. The survey was validated …

Preceptor Development: Identifying The Best Modality For Building Clinical Educators, G W. Cohen, R M. Lopez, A J. Tritsch

Clinical Practice in Athletic Training

Introduction: Preceptor training and development are not standardized within the athletic training profession. The Commission on Accreditation of Athletic Training Education (CAATE) requires that Athletic Training Programs provide an ongoing education plan for preceptors to promote a constructive learning environment for students. However, with the rapid expansion of clinical education opportunities outside of institutions' immediate area, programs must identify how to reach all their preceptors and uphold their programmatic expectations for clinical educators. Methods: The investigators conducted a cohort pre-test-post-test design study. A preceptor development program (PDP) was created and grounded in the theory of gamified learning and adult learning …

The Financial Stresses That Affect Athletic Training Students: A Qualitative Investigation, C Kuehner-Boyer, E León Zaragoza

Clinical Practice in Athletic Training

Introduction: A recent survey examining barriers that affect athletic training students found that financial-related barriers created significant stress for students in professional athletic training programs. The need to work while attending a professional athletic training program was the highest reported barrier with 54.82% of respondents indicating that this was a barrier for them during their program. Beyond the overall reporting rate, the need to work while completing a professional athletic training program was indicated by athletic training students to be the barrier that they encountered the most frequently with respondents reporting that this was a stress for them between monthly …

Musculoskeletal Tumors Disguised As Orthopedic Injuries: A Case Report, A Summers

Clinical Practice in Athletic Training

Background: Musculoskeletal tumors are relatively rare, accounting for only 0.2 to 0.5% of all malignancies across all age groups. More specifically, Pigmented Villonodular Synovitis, a type of musculoskeletal tumor, has an incidence rate of 1.8 cases per one million people in a population. This benign, proliferative disease is a type of tenosynovial giant cell tumor that can affect the soft tissue lining of joints, bursae, and tendon sheaths. These joint-related tumors often present with an insidious onset and non-specific physical exam findings. Therefore, they are often mistaken for other, more common orthopedic injuries, making them difficult to diagnose. Patient Information: …