Digital Commons Network^™

Let’S Be Cool About It: Anticipating Proper, Whole-Human Cryopreservation And The Necessary Oversight For Adequate Consumer Protection, Peter Lyon

Minnesota Journal of Law, Science & Technology

No abstract provided.

Emergence Of Childhood Adversities Impacting Coping Strategies Among African American Adults, Cherise Jenean Bailey

Walden Dissertations and Doctoral Studies

Adverse childhood experiences (ACEs) are traumatic events occurring before age 18 that negatively impact mental, physical, and emotional well-being. The impact of ACEs and how they influence coping strategies of African American undergraduate college students between 18 and 22 is less known. This study involved employing a nonexperimental quantitative cross-sectional research design to identify coping strategies of African American undergraduate college students between 18 and 22. Additionally, the study involved identifying factors that predict coping strategies among this population. The transactional theory of stress and coping was the theoretical framework for the study. Online survey tools were used to collect …

Barriers To Nigerian Community Members In The United States Seeking Mental Health Treatment, Chinwendu Ejekwu

Walden Dissertations and Doctoral Studies

Nigerian immigrants in the United States face significant challenges in accessing mental health care due to various cultural and systemic barriers. This generic qualitative study, guided by Vygotsky’s sociocultural theory, was conducted to explore the barriers encountered by Nigerian community members in seeking mental health treatment in the United States. Data were obtained through semistructured interviews where nine Nigerian immigrants presented their perceptions and experiences concerning barriers to Nigerian community members seeking mental health treatment in the United States. Thematic analysis followed the six-step data analysis method, leading to three themes. The themes identified are: (a) mental health is a …

Flow Dynamics Of Agricultural Waste Nanofibers: Shear, Temperature, And Oscillatory Insights, Bilge N. Altay, Burak Aksoy, James Atkinson, Christopher Lewis, Carlos Diaz-Acosta, Raymond Francis

Articles

The rheology and fiber size of corn stover (CS) and cleaned cotton gin trash (CGT) cellulose nanofibers (CNFs) were studied including behaviors at both moderate and extremely high shear rates, to simulate industrial processes ranging from mixing and pumping to high-speed coating, printing, and extrusion. Particle size analyzer showed that 99% of CS fibers measured around 226 nm, while 85% of CGT fibers were approximately 143 nm. Both CS and CGT CNFs formed gel-like suspensions, and shear flow tests revealed that all samples exhibited shear-thinning behavior, allowing easy flow under shear forces. Gels with higher solid content (1%) demonstrated extended …

Ultrasound-Triggered Release Of Vancomycin From A Novel Spinal Device: Antibiotic Release And Efficacy In Vivo, Lauren J. Delaney, Priscilla Machado, Ji-Bin Liu, Rachel Evans, Asia Winslow, Neil Zhao, Christopher K. Kepler, Rajkishen Narayanan, Teeto Ezeonu, Viren Soni, Gagan Kaushal, Rachel Hilliard, Thomas P. Schaer, Noreen J. Hickok, Flemming Forsberg

Department of Orthopaedic Surgery Faculty Papers

Post-surgical spinal infection occurs in up to 20 % of patients, despite aggressive peri-operative antibiotic treatments. To improve prophylaxis, we have designed and evaluated an ultrasound-activated prophylactic antibiotic release system to combat post-surgical bacterial survival. Polylactic acid (PLA) clips (1 cm³) were 3D-printed with an interior reservoir (0.8 cm³) for carrying drug payload, specifically vancomycin (VAN). Under IACUC approval, clips were surgically implanted into the spines of sheep (n = 9) and swine (n = 2) by removing the spinous process at several levels of the lumbar spine. In the sheep, clips were insonated and the …

Immunological Biomarkers Of Response And Resistance To Treatment With Cabozantinib And Nivolumab In Recurrent Endometrial Cancer, Vladimir Roudko, Diane Marie Del Valle, Emir Radkevich, Geoffrey Kelly, Xie Hui, Manishkumar Patel, Edgar Gonzalez-Kozlova, Kevin Tuballes, Howard Streicher, Swati Atale, Lisa Wang, Benito Czinczin, Seunghee Kim-Schulze, Ignacio I Wistuba, Cara L Haymaker, Gheath Al-Atrash, Ganiraju Manyam, Jianjun Zhang, Ryan Thompson, Mayte Suarez-Farinas, Stephanie Lheureux, Sacha Gnjatic

Faculty, Staff and Student Publications

Background: Antiangiogenics combined with immune checkpoint blockade have become standard of care for recurrent endometrial cancer after standard platinum-based chemotherapy. To dissect mechanisms and define biomarkers associated with clinical outcomes to these combinations, we applied multidimensional immune monitoring to peripheral blood specimens collected from a randomized phase 2 trial of nivolumab with or without cabozantinib in 75 evaluable patients with recurrent endometrial cancer (NCI ETCTN 10104, NCT03367741). This trial demonstrated superiority of the combination to nivolumab alone.

Methods and results: Using Olink proteomics, mass cytometry, tumor antigen-specific ELISA, and whole exome tumor sequencing, we identified longitudinal immune signatures specific …

Monitoring And Modeling Legacy Tree Response To Restoration Treatments In The Klamath Mountains, Oregon, Usa, Isaac Joseph Ball

Dissertations and Theses

Climate change and its disruption of historical drought and wildfire patterns pose a substantial threat to forest health in the western United States. This threat is compounded by past management practices like fire suppression. The largest, oldest, and most ecologically valuable trees are particularly vulnerable, making their conservation a key objective of climate-adaptive forest management. Restoration treatments such as mechanical thinning have been shown to enhance tree growth and drought resilience in dry conifer forests, but long-term monitoring is necessary to understand their sustained effects. This study used dendroecological tree-ring analysis to investigate the effects of thinning on the growth, …

Mapping Snorna-Target Rna Interactions In An Rna-Binding Protein-Dependent Manner With Chimeric Eclip, Zhuoyi Song, Bongmin Bae, Simon Schnabl, Fei Yuan, Thareendra De Zoysa, Maureen V Akinyi, Charlotte A Le Roux, Karine Choquet, Amanda J Whipple, Eric L Van Nostrand

Faculty, Staff and Students Publications

Background: Small nucleolar RNAs (snoRNAs) are non-coding RNAs that function in ribosome and spliceosome biogenesis, primarily by guiding modifying enzymes to specific sites on ribosomal RNA (rRNA) and spliceosomal RNA (snRNA). However, many orphan snoRNAs remain uncharacterized, with unidentified or unvalidated targets, and studies on additional snoRNA-associated proteins are limited.

Results: We adapted an enhanced chimeric eCLIP approach to comprehensively profile snoRNA-target RNA interactions using both core and accessory snoRNA-binding proteins as baits. Using core snoRNA-binding proteins, we confirmed most annotated snoRNA-rRNA and snoRNA-snRNA interactions in mouse and human cell lines and called novel, high-confidence interactions for orphan snoRNAs. While …

Conformational Flexibility Is A Critical Factor In Designing Broad-Spectrum Human Norovirus Protease Inhibitors, Son Pham, Boyang Zhao, Neetu Neetu, Banumathi Sankaran, Ketki Patil, Sasirekha Ramani, Yongcheng Song, Mary K Estes, Timothy Palzkill, B V Venkataram Prasad

Faculty, Staff and Students Publications

UNLABELLED: Human norovirus (HuNoV) is a leading cause of gastroenteritis worldwide and is associated with significant morbidity, mortality, and economic impact. There are currently no licensed antiviral drugs for the treatment of HuNoV-associated gastroenteritis. The HuNoV protease plays a critical role in the initiation of virus replication by cleaving the polyprotein. Thus, it is an ideal target for developing antiviral small-molecule inhibitors. While rupintrivir, a potent small-molecule inhibitor of several picornavirus proteases, effectively inhibits GI.1 protease, it is an order of magnitude less effective against GII protease. Other GI.1 protease inhibitors also tend to be less effective against GII proteases. …

Human Intestinal Enteroids For Evaluating The Persistence Of Infectious Human Norovirus In Raw Surface Freshwater, Malak A Esseili, Revati Narwankar, Riya Hooda, Veronica Costantini, Mary K Estes, Jan Vinjé, Issmat I Kassem

Faculty, Staff and Students Publications

Globally, human norovirus (HuNoV) is the leading cause of foodborne illnesses. Norovirus transmission to fresh produce can occur via several sources, including contaminated irrigation water. HuNoV RNA has been detected in freshwater resources, but knowledge about virus infectivity is limited due to a historical lack of a HuNoV cell culture. Recently, HuNoV was shown to replicate in human intestinal enteroids (HIE). The objective of this study was to use HIE to evaluate the persistence of infectious HuNoV in raw (i.e. biologically active) surface freshwater. The virus was spiked into freshwater microcosms sampled from three freshwater ponds and then incubated inside …

Clostridioides Difficile Colonization Is Not Mediated By Bile Salts And Utilizes Stickland Fermentation Of Proline In An In Vitro Model, Xiaoyun Huang, April E Johnson, Joshua N Brehm, Thi Van Thanh Do, Thomas A Auchtung, Hugh C Mccullough, Armando I Lerma, Sigmund J Haidacher, Kathleen M Hoch, Thomas D Horvath, Joseph A Sorg, Anthony M Haag, Jennifer M Auchtung

Faculty, Staff and Students Publications

Treatment with antibiotics is a major risk factor for Clostridioides difficile infection, likely due to depletion of the gastrointestinal microbiota. Two microbiota-mediated mechanisms thought to limit C. difficile colonization include the conversion of conjugated primary bile salts into secondary bile salts toxic to C. difficile growth and competition between the microbiota and C. difficile for limiting nutrients. Using a continuous flow model that simulates the nutrient conditions of the distal colon, we investigated how treatment with 6 clinically used antibiotics influenced susceptibility to C. difficile infection in 12 different microbial communities cultivated from healthy individuals. Antibiotic treatment reduced microbial richness; …

Associations Of Long-Term Exposure To Temperature With Coronary Artery Calcification Risk Among Middle-Aged Adults: The Coronary Artery Risk Development In Young Adults (Cardia) Study, Dandan Zhao, Jie Yao, Yuanfei Li, David R Jacobs, Yinan Zheng, Chunyu Liu, Yingbin Fu, Margaret M Deangelis, Donald Lloyd-Jones, Lifang Hou, Kai Zhang

Faculty, Staff and Students Publications

BACKGROUND: The impact of ambient temperature on population health has drawn increasing attention as climate change drives more extreme temperatures globally. However, little research has investigated its connection to subclinical cardiovascular diseases. This study aims to examine the impact of long-term exposure to temperature on coronary artery calcification (CAC) among middle-aged Black and White adults in four U.S. areas with varying climate and weather conditions.

METHODS: This study compiled long-term environmental temperature data and individual coronary artery Agatston score (0 vs. >0) from the Coronary Artery Risk Development in Young Adults study. It employed logistic regression and examined the influences …

Atp-Sensitive Potassium Channels Alter Glycolytic Flux To Modulate Cortical Activity And Sleep, Nicholas J Constantino, Caitlin M Carroll, Holden C Williams, Hemendra J Vekaria, Carla M Yuede, Kai Saito, Patrick W Sheehan, J Andy Snipes, Marcus E Raichle, Erik S Musiek, Patrick G Sullivan, Josh M Morganti, Lance A Johnson, Shannon L Macauley

2020-Current year OA Pubs

Metabolism plays a key role in the maintenance of sleep/wake states. Brain lactate fluctuations are a biomarker of sleep/wake transitions, where increased interstitial fluid (ISF) lactate levels are associated with wakefulness and decreased ISF lactate is required for sleep. ATP-sensitive potassium (K

Epidemiology And Genetic Determination Of Measures Of Peripheral Vascular Health In The Long Life Family Study, Deidra R Fricke, Ryan K Cvejkus, Emma Barinas-Mitchell, Mary F Feitosa, Joanne M Murabito, Sandeep Acharya, Michael R Brent, E Warwick Daw, Ryan L Minster, Joseph M Zmuda, Allison L Kuipers

2020-Current year OA Pubs

Peripheral artery disease (PAD) is a major contributor to morbidity in older adults. We aimed to determine genetic and non-genetic determinants of PAD and ankle-brachial index (ABI) in the Long Life Family Study (LLFS). 3006 individuals had ABI assessment, including 1090 probands (mean age 89), 1554 offspring (mean age 60) and 362 spousal controls (mean age 61). Outcomes include minimum of right and left ABIs and PAD (ABI <0.9). Stepwise regression determined independent significant non-genetic correlates of ABI and PAD. Genomewide association and linkage analyses were adjusted for age, sex, study center, significant principal components, and independent predictors. All analyses accounted for familial relatedness. Median ABI was 1.16 and 7.4% had PAD (18.2% probands, 1.0% offspring, 1.9% controls). Correlates of PAD and lower ABI included age, SBP, and creatinine (ABI only); BMI (ABI only), HDL (ABI only) and DBP (PAD only); and antihypertensive use, current smoking, female sex (ABI only), and high school noncompletion (ABI only). Genomewide linkage identified 1 region (15q12-q13) and association identified 3 single nucleotide polymorphisms (rs780213, rs12512857, rs79644420) of interest. In these families, PAD prevalence was low compared to other studies of older adults. We identified four genomic sites that may harbor variants associated with protection from PAD.

Agouti And Bmp Signaling Drive A Naturally Occurring Fate Conversion Of Melanophores To Leucophores In Zebrafish, Delai Huang, Emaan H. Kapadia, Yipeng Liang, Leah P. Shriver, Shengkun Dai, Gary J. Patti, Bruno M. Humbel, Vincent Laudet, David M. Parichy

2020-Current year OA Pubs

No abstract provided.

Tifab Modulates Metabolic Pathways In Kmt2a::Mllt3-Induced Aml Through Hnf4a, Yang Wang, Yan Xiu, Qianze Dong, Jinming Zhao, Kelao Neumbo, Masaru Miyagi, Nicholas Borcherding, Lin Fu, Havana De Celis, Nicolas Pintozzi, Daniel T Starczynowski, Chen Zhao

2020-Current year OA Pubs

Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein with forkhead-associated domain B (TIFAB), an inhibitor of NF-κB signaling, plays critical roles in hematopoiesis, myelodysplastic neoplasms, and leukemia. We previously demonstrated that Tifab enhances KMT2A::MLLT3-driven acute myeloid leukemia (AML) by either upregulating Hoxa9 or through ubiquitin-specific peptidase 15-mediated downregulation of p53 signaling. In this study, we show that Tifab deletion in KMT2A::MLLT3-induced AML impairs leukemia stem/progenitor cell (LSPC) engraftment, glucose uptake, and mitochondrial function. Gene set enrichment analysis reveals that Tifab deletion downregulates MYC, HOXA9/MEIS1, mTORC1 signaling, and genes involved in glycolysis and oxidative phosphorylation. By comparing genes upregulated in TIFAB-overexpressing …

2′-Fucosyllactose Inhibits Human Norovirus Replication In Human Intestinal Enteroids, Ketki Patil, B Vijayalakshmi Ayyar, Nicole M Hayes, Frederick H Neill, Lars Bode, Mary K Estes, Robert L Atmar, Sasirekha Ramani

Faculty, Staff and Students Publications

Human noroviruses (HuNoVs) are the leading cause of acute gastroenteritis worldwide. Currently, there are no targeted antivirals for the treatment of HuNoV infection. Histo-blood group antigens (HBGAs) on the intestinal epithelium are cellular attachment factors for HuNoVs; molecules that block the binding of HuNoVs to HBGAs thus have the potential to be developed as antivirals. Human milk oligosaccharides (HMOs) are glycans in human milk with structures analogous to HBGAs. HMOs have been shown to act as decoy receptors to prevent the attachment of multiple enteric pathogens to host cells. Previous X-ray crystallography studies have demonstrated the binding of HMO 2′-fucosyllactose …

Pskh1 Kinase Activity Is Differentially Modulated Via Allosteric Binding Of Ca2+ Sensor Proteins, Christopher R Horne, Toby A Dite, Samuel N Young, Lucy J Mather, Laura F Dagley, Jared L Johnson, Tomer M Yaron-Barir, Emily M Huntsman, Leonard A Daly, Dominic P Byrne, Antonia L Cadell, Boaz H Ng, Jumana Yousef, Dylan H Multari, Lianju Shen, Luke M Mcaloon, Gerard Manning, Mark A Febbraio, Anthony R Means, Lewis C Cantley, Maria C Tanzer, David R Croucher, Claire E Eyers, Patrick A Eyers, John W Scott, James M Murphy

Children’s Nutrition Research Center Staff Publications

Protein Serine Kinase H1 (PSKH1) was recently identified as a crucial factor in kidney development and is overexpressed in prostate, lung, and kidney cancers. However, little is known about PSKH1 regulatory mechanisms, leading to its classification as a “dark” kinase. Here, we used biochemistry and mass spectrometry to define PSKH1’s consensus substrate motif, protein interactors, and how interactors, including Ca2+ sensor proteins, promote or suppress activity. Intriguingly, despite the absence of a canonical Calmodulin binding motif, Ca2+-Calmodulin activated PSKH1 while, in contrast, the ER-resident Ca2+ sensor of the Cab45, Reticulocalbin, Erc55, Calumenin (CREC) family, Reticulocalbin-3, suppressed PSKH1 catalytic activity. In …

Evaluating Zinc Deficiency As A Contributing Factor To Poor Glycemic Control In Type 2 Diabetes Iraqi Patients: A Case-Control Study", Noor Mohammed Obaid, Mustafa Mohammed Albassam, Yasser Kadhim Hashem Al-Zwaini

Maaen Journal for Medical Sciences

Background: Type 2 diabetes mellitus (T2DM) is a common metabolic disorder, characterized by chronic hyperglycemia resulting from insulin resistance and beta-cell dysfunction. One nutrient deficiency specifically associated with the progression of diabetes is that of micronutrients, especially zinc. This paper reviews the role of zinc in insulin synthesis, secretion, and action, whilst reviewing the potential interaction with oral antidiabetic drugs.

Objective: This study aimed to investigate serum zinc concentrations in T2DM patients and examine their correlation with fasting blood glucose (FBG) levels in individuals using oral antidiabetic medications.

Methods:A case-control study was conducted from March 2023 to September 2023 …

Extraterritorial Act Versus The Indigenous People Protection: An Analysis Of The European Union Deforestation-Free Regulation, Aartje Tehupeiory, Putu George Matthew Simbolon

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

At first glance, indigenous people and international trade appear to be two separate issues. However, this perception does not apply in the case of European Regulation 2023/1115. This study aims to provide an understanding of how Indonesia should respond to the EU DFR, which has affected Indonesia’s national interests in protecting indigenous people. This study applied a normative method through doctrinal and conceptual approaches to achieve the objective. The study covers two main discussions. The first explains how due diligence under the EU DFR has indirectly pushed Indonesia to become an EU trading partner and provide more excellent protection for …

Questioning Food Security In Green Constitution Conception: Realizing Sustainable Development Goals (Sdgs) In Indonesia, Rahayu Subekti, Tsabbita Ahmilul Husna, Putri Balqis Salsabila

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Research on the constitution, food security, and sustainable development have become widely explored. However, issues related to the legal framework in the context of a green constitution remain unresolved. This is particularly evident in Indonesia’s efforts to address the food crisis, which has led to substantial deforestation. Therefore, this research aims to analyze the implementation of food security efforts in line with a green constitution in Indonesia. Despite the potential for adopting sustainability for future generations, there is hesitance in implementing articles related to a green constitution in food security activities. This legal issue is examined as normative research using …

The Inadequacy Of Legal Provisions On Workplace Sexual Harassment In Nigeria And Ghana: The Way Forward, Emuobo Emudainohwo

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Sexual harassment has been a persistent problem in workplaces in Nigeria and Ghana. The legal provisions in both jurisdictions generally focus on the definition of “sexual harassment” without remedies for the harassment, sanctions, enforcement procedures, anti-sexual harassment policies, complaint procedures, etc., that can control sexual harassment in the workplace. The article examines the scantiness and inadequacy of legal provisions on workplace sexual harassment in Nigeria and Ghana, suggesting a way forward. The doctrinal research method has been deployed, focusing on relevant Nigerian and Ghanaian legal provisions. The article considers the organization theory of sexual harassment, using it as a framework, …

A Discourse Of The Indigenous Peoples' Rights And Their Contributions To The Indonesian Development: Lessons Learned From New Zealand, Mohamad Jamin, Sapto Hermawan, Mulyanto Mulyanto

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The struggles of indigenous peoples in both New Zealand and Indonesia to gain legal recognition remain ongoing. This study focuses on two central aspects. Firstly, it examines the historical-legal journey of indigenous peoples in their quest for legal acknowledgment. Secondly, it makes a comparative analysis with New Zealand, highlighting the potential contributions that indigenous peoples can provide to their respective countries. The study follows a legal research methodology, linking existing issues with authoritative sources and real-world situations. The findings reveal that in New Zealand, indigenous peoples possess a legal standing, albeit not entirely comprehensive. Conversely, Indonesian regulations do not provide …

The Opportunities For Surrogacy Legalization Between The Right To Have Children And A Loophole Of Trafficking, Wawan Edi Prastiyo, Gde Made Swardhana

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The phenomenon of producing surrogate mother facilities has been recognized in some countries, although Indonesia indirectly prohibits the practice. The practice is also feared to be a new form of human trafficking. Therefore, this study aims to evaluate the opportunities for surrogacy legalization regarding its perspectives between human rights and the loophole of trafficking. In this study, three problems were formulated: (1) the legal status of children born from a surrogate mother; (2) the legality of a surrogate mother in Indonesian law; and (3) the opportunities for surrogacy legalization in legal reform. This study is a normative juridical study that …

Human Genetic Engineering: Should Indonesia Regulate It?, Hari Sutra Disemadi

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Human genetic engineering raises pros and cons. Despite the potential to contribute to the health sector, it can cause several problems. While, in theory, it goes against nature and against other conservative beliefs, human genetic engineering gains important support from Transhumanism—a philosophy promoting the scientific evolution of the human race. This study determines the relevancy regulation of human genetic engineering on a global scope and how it affects the prospects of regulating human genetic engineering in Indonesia. The study aims to provide consideration for Indonesia in determining the legality status of human genetic engineering, through analyses of legal constructions surrounding …

The Existence Of Indonesian National Research And Innovation Agency: The Academic Freedom’S Perspective, Muhamad Dzadit Taqwa, M. Irfan Dwi Putra, Muhamad Ali Muharam

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Recently, Indonesia has taken a policy to merge all the research institutions, which were classified as non-ministerial institutions, into the National Research and Innovation Agency (BRIN –Badan Riset dan Inovasi Nasional). The BRIN is expected to (1) reduce the research costs for the research institutions; and (2) integrate and harmonize these institutions. On the other hand, the policy has drawn constitutional law scholars' attention. Many of them who concern that BRIN intervenes academic freedom in Indonesia. The main factor that causes the concern is the subordinate relationship between the President and the BRIN that restrain researchers from their …

Children Involvement In Terrorism Activities: Perpetrator Or A Victim? (A Study In The Circle Of Violence), Wawan Edi Prastiyo, I Ketut Rai Setiabudhi

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Terrorism is an extraordinary crime since it violates human rights. However, it will be different if children commit it. The legal approach is not necessarily taken against children who become terrorists. The problem of children's involvement in terrorist activities does not end there. Another important issue that must also be considered is children of terrorist parents. They must be rescued from a violent social environment. In this study, we will discuss the position of children as victims in the cycle of violence of terrorism and criminal policies in overcoming the involvement of children in terrorism activities. This research is normative …

The Judicial Pardon Arrangement As A Method Of Court Decision In The Reform Of Indonesian Criminal Law Procedure, Mufatikhatul Farikhah

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Judicial Pardon is a new concept formulated in the 2019 Draft of the Criminal Code. The concept refers to the judges’ new powers to forgive defendants who are convicted guilty. However, the formulation of the concept has not been adjusted to the formulation of decision types in the draft of the Criminal Law Procedure. There has to be a harmonization between the Draft of the Criminal Code and the Draft of the Criminal Law Procedure. This article is based on a legal study on the importance of regulating judicial pardon as a form of the court decision. It reveals that …

An Endless Struggle Of Fighting Discrimination In The Name Of Human Rights Protection, Hernadi Affandi, Tarsisius Murwadji

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

The Incident of George Floyd’s death reminds people of the peril of discrimination that still exists within the American society. The incident has triggered worldwide reactions from people who feel sympathy for the victim and reject racism. To eliminate racial discrimination, every modern society needs to remove any negative paradigm towards intergroup relation. In the context of the United States, the American Government has the responsibility to protect the rights of citizens from any forms of discrimination. That includes racial discrimination. In addition, people have to be reminiscent of the danger of racial discrimination in the modern era. The danger …

Diskursus Perumusan Ideologi Sebagai Perbuatan Pidana Dalam Rancangan Kitab Undang-Undang Hukum Pidana 2015, Rocky Marbun

Padjadjaran Jurnal Ilmu Hukum (Journal of Law)

Reformasi Hukum Pidana pasca kemerdekaan Indonesia telah dimulai sejak 1963 terhadap Kitab Undang-Undang Hukum Pidana sebagai warisan dari kolonial Belanda. Semangat kemerdekaan menginginkan adanya reformasi, bukan hanya terhadap produk hukum yang masih bernuansa kolonialisme, namun juga pada cara pandang atau pola pikir dalam memandang permasalahan hukum. Salah satu pola pikir yang mendapat pengaruh warisan kolonialisme dalam mempertahankan rust en orde (menjaga keamanan dan ketertiban) adalah dengan memasukkan instrumen hukum guna mempertahankan kestabilan politik. Sehingga negara masih memandang urgenitas dari tindakan isolasir terhadap ideologi negara dengan melakukan pelarangan terhadap penyebaran ideologi Komunisme/Marxisme/Leninisme. Faktor terbesar dari perumusan pelarangan tersebut adalah pengalaman hitam …