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Proceedings Of The 81st Annual Meeting, Midwestern Association Of Graduate Schools

Midwestern Association of Graduate Schools

Table of Contents: 2025 MAGS Annual Meeting

Indianapolis, Indiana | April 2–4, 2025 Theme: Restart Your Engines to Renew, Refresh, and Reimagine Graduate Education!

Wednesday, April 2, 2025

Preconference: New Graduate Administrators Workshop Plenary I – Issues and Opportunities for Graduate Education: What Is and What Can Be

• Fostering Diversity and Inclusion in Graduate Programs: Supporting Holmes Scholars in Rural Universities
• My Graduation Checklist: Using Canvas to Improve Graduate Students’ Final Experiences at the University of Kansas
• Empowering Successful Mentoring Relationships: Success Stories from the Indiana University, Indianapolis Graduate Mentoring Center
• Moving Past Information Overload: Reimagining a Student-Centered Graduate Orientation …

Flaws In The Preemption Defense To Liability Claims Against Generic Drug Manufacturers, Lars Noah

University of Miami Law Review

More than a dozen years have passed since the U.S. Supreme Court decided that federal preemption protects manufacturers of generic (but not brand-name) drugs from most types of products liability claims. This seemingly arbitrary distinction sprang from a peculiarity in the regulations of the U.S. Food and Drug Administration (FDA). That agency soon thereafter proposed to modify its rules in order to eliminate this asymmetry in how the implied preemption defense worked to bar inadequate warning claims, but its effort ultimately failed, while lower courts have confronted some creative efforts to circumvent the special protection enjoyed by generic drug manufacturers. …

He Said, She Said: Deconstructing Gender In Our Own World Through Our Own Languages, William K. Coulthard

SPARK Symposium Presentations

Both language and gender are social constructs which we humans have created to produce an order to the world, and this essay illustrates the ways in which language influences both our perceptions of gender and the world of people who subvert so-called natural gender norms. Because gender, unlike sex, is a social construct to which we ascribe particular images and words, language can affect not only the identity of the person in question but also their relationships, careers, and societal attitudes toward gender. Ursula Le Guin, in her 1969 science fiction novel The Left Hand of Darkness, deconstructs our earthly …

Experts Focus On Democracy, Psychedelics For Brain Awareness Week, Marvis Herring

University of Mississippi News

OXFORD, Miss. – Two renowned researchers will discuss the brain's role in making political decisions and the reduction of negative perceptions concerning the use of therapeutic psychedelics during the University of Mississippi's Brain Awareness Week, April 8-11.

Enhancing Eye Anatomy Education: Integrating 3d Models In Open Educational Resources, Hayley Nickels Yancey

Instructional Psychology and Technology Graduate Student Projects

This project explores how interactive 3D models can enhance eye anatomy education within the framework of open educational resources (OER). Recognizing that students in anatomy and physiology courses often struggle to recognize anatomical structures from multiple perspectives—and frequently lack access to high-quality, low-cost study tools—this project addressed these gaps by designing and developing a custom, interactive 3D model of the human eye. Created using Blender and embedded into a web interface via Verge3D, the model allows users to rotate, zoom, highlight, and isolate structures of the eye, including both external and internal components. The tool was designed specifically for students …

The Bg News April 2, 2025, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. April 02, 2025. Volume 104-Issue 23.

Animating The Mechanism Of Action Of The Novel Glioblastoma Vaccine Survaxm, Sheila Figel

Theses

Glioblastoma (GBM) is a deadly type of malignant brain tumor affecting over 11,000 people in the United States each year. Treatment options for GBM are limited, with the majority of patients receiving surgery and chemoradiation, and surviving around 15 months. New therapies are desperately needed. A novel peptide vaccine, SurVaxM, has shown promise in phase I and II clinical trials, and is currently under investigation in a Phase IIb trial (the “SURVIVE” trial) for newly diagnosed GBM. As SurVaxM moves closer to FDA approval, there is a need for education about the agent and how it works. In order to …

Methylome-Wide Association Analyses Of Lipids And Modifying Effects Of Behavioral Factors In Diverse Race And Ethnicity Participants, Yao Hu, Jeff Haessler, Jessica I Lundin, Burcu F Darst, Eric A Whitsel, Megan Grove, Weihua Guan, Rui Xia, Mindy Szeto, Laura M Raffield, Scott Ratliff, Yuxuan Wang, Xuzhi Wang, Alison E Fohner, Megan T Lynch, Yesha M Patel, S Lani Park, Huichun Xu, Braxton D Mitchell, Joshua C Bis, Nona Sotoodehnia, Jennifer A Brody, Bruce M Psaty, Gina M Peloso, Michael Y Tsai, Stephen S Rich, Jerome I Rotter, Jennifer A Smith, Sharon L R Kardia, Alex P Reiner, Leslie Lange, Myriam Fornage, James S Pankow, Mariaelisa Graff, Kari E North, Charles Kooperberg, Ulrike Peters

Faculty, Staff and Student Publications

Circulating lipid concentrations are clinically associated with cardiometabolic diseases. The phenotypic variance explained by identified genetic variants remains limited, highlighting the importance of searching for additional factors beyond genetic sequence variants. DNA methylation has been linked to lipid concentrations in previous studies, although most of the studies harbored moderate sample sizes and exhibited underrepresentation of non-European ancestry populations. In addition, knowledge of nongenetic factors on lipid profiles is extremely limited. In the Population Architecture Using Genomics and Epidemiology (PAGE) Study, we performed methylome-wide association analysis on 9,561 participants from diverse race and ethnicity backgrounds for HDL-c, LDL-c, TC, and TG …

Integrating Standards For Infrastructure Improvement And Resilience In University Curricula, Lisa Greenwood, Jennifer Schneider, Sumita Mishra, Yewande S. Abraham, Shriram Karpoora Sundara Pandian

Articles

In today’s ever-changing world, we are increasingly vulnerable to shocks and stresses that disrupt industry and society. Persistent threats from natural and manmade hazards require our communities and infrastructure to be resilient despite possible disruption. Creating robust infrastructures is founded on operational and physical standards to withstand and respond to threats such as environmental exposures, climate change, and informational security breaches. The significant U.S. investment in infrastructure projects through the Infrastructure Investment and Jobs Act has amplified the need for professionals in engineering and related fields who – in addition to technical knowledge - possess the necessary knowledge and skill …

Reframing Information Seeking In The Age Of Generative Ai: A Critical And Humanistic Approach, Joseph Kevin Sebastian

Library Faculty Research

Information-seeking has long been the subject of theoretical modeling, often drawing from cognitive, behavioral, computational, and even evolutionary perspectives to explain how individuals navigate, filter, and utilize information. Several dominant frameworks—Carol Kuhlthau’s Information Search Process, Marcia Bates’ Berrypicking Model, Peter Pirolli & Stuart Card’s Information Foraging Theory, Kiyohiko Nakamura’s Information Criteria framework, and Ian Ruthven’s Information Shaping Theory —have provided structured ways of understanding how people interact with information environments. However, while these frameworks offer valuable insights, they often operate within mechanistic or efficiency-driven paradigms, which risk overlooking the complex, embodied, and socioculturally situated nature of human information behaviors. These …

Dataset: Compositional Analysis And Hydrothermal Liquefaction Of A High-Ash Microalgae Biofilm, Jacob Watkins, Hamza Abdellaoui, Elise Barton, Clayton Lords, Ronald C. Sims

Biological Engineering Student Research

This dataset contains biochemical composition data and hydrothermal liquefaction (HTL) yield results for a high-ash microalgae biofilm which was cultivated in effluent from a mesophilic anaerobic digester using polyethylene rotating algae biofilm reactors (RABRs). These data were originally collected for use in a techno-economic analysis of biocrude, biodiesel, and bioplastic production from algae that was cultivated using RABRs for municipal wastewater reclamation.

Biochemical data for the microalgae biomass includes bulk protein, measured both using the Bradford protein assay and by multiplying total N; carbohydrate content, measured using a 3-methyl-2-benzothiazolinone hydrazone / dithiothreitol (MBTH/DTT) assay; total lipid content, measured using a …

Assessment Of Cognitive Domains In Major Depressive Disorders Using The Cambridge Neuropsychological Test Automated Battery (Cantab): Systematic Review And Meta-Analysis Of Cross-Sectional And Longitudinal Studies, Danilo Arnone, Reshma Ramaraj, Linda Östlundh, Teresa Arora, Syed Javaid, Romona Devi Govender, Emmanuel Stip, Allan H. Young

All Works

Cognitive difficulties are known to persist after remission of symptoms and to affect psychosocial functioning and quality of life. Cognitive function, measured with the Cambridge Neuro-psychological Test Automated Battery (CANTAB), is a reliable approach to measure cognitive function in major depression. This systematic review and meta-analysis appraise cross-sectional and longitudinal studies that used specific CANTAB tests to measure cognitive function in major depression and the effect of treatment (PROSPERO ID: CRD42022355903). 1212 studies were identified and 41 were included, 1793 patients and 1445 healthy controls. Deficits in executive functions were detected with the Stocking Of Cambridge (SOC) ‘number of problems …

The Microbiome-Restorative Potential Of Ibezapolstat For The Treatment Of Clostridioides Difficile Infection Is Predicted Through Variant Polc-Type Dna Polymerase Iii In Lachnospiraceae And Oscillospiraceae, Jacob K Mcpherson, Julian G Hurdle, Matthew L Baker, Tahir Hussain, Ashok Kumar, Kevin W Garey

Faculty, Staff and Student Publications

Ibezapolstat (IBZ), a first-in-class antibiotic targeting the PolC-type DNA polymerase III alpha-subunit (PolC) in low G + C bacteria, is in clinical development for the treatment of Clostridioides difficile infection (CDI). In the phase 2 trials, IBZ had potent activity against C. difficile while sparing or causing regrowth of Lachnospiraceae, Oscillospiraceae, and Erysipelotrichales, common commensal low G + C bacteria. The purpose of this study was to utilize in silico approaches to better interpret the narrower than expected IBZ spectrum of activity. IBZ susceptibility to human commensal microbiota was predicted using genomic analysis and PolC phylogenetic tree construction in relation …

Chronic Viral Mimicry Induction Following P53 Loss Promotes Immune Evasion, Charles A Ishak, Sajid A Marhon, Naïri Tchrakian, Anjelica Hodgson, Helen Loo Yau, Isabela M Gonzaga, Melanie Peralta, Ilinca M Lungu, Stephanie Gomez, Sheng-Ben Liang, Shu Yi Shen, Raymond Chen, Jocelyn Chen, Biji Chatterjee, Kevin N Wanniarachchi, Junwoo Lee, Nicholas Zehrbach, Amir Hosseini, Parinaz Mehdipour, Siyu Sun, Alexander Solovyov, Ilias Ettayebi, Kyle E Francis, Aobo He, Taiyi Wu, Shengrui Feng, Tiago Da Silva Medina, Felipe Campos De Almeida, Jane Bayani, Jason Li, Spencer Macdonald, Yadong Wang, Sarah S Garcia, Elisa Arthofer, Noor Diab, Aneil Srivastava, Paul Tran Austin, Peter J B Sabatini, Benjamin D Greenbaum, Catherine A O'Brien, Trevor G Shepherd, Ming Sound Tsao, Katherine B Chiappinelli, Amit M Oza, Blaise A Clarke, Robert Rottapel, Stephanie Lheureux, Daniel D De Carvalho

Faculty, Staff and Student Publications

Epigenetic therapies facilitate transcription of immunogenic repetitive elements that cull cancer cells through ‘viral mimicry’ responses. Paradoxically, cancer-initiating events also facilitate transcription of repetitive elements. Contributions of repetitive element transcription towards cancer initiation, and the mechanisms by which cancer cells evade lethal viral mimicry responses during tumor initiation remain poorly understood. In this report, we characterize premalignant lesions of the fallopian tube along with syngeneic epithelial ovarian cancer models to explore the earliest events of tumorigenesis following loss of the p53 tumor suppressor protein. We report that p53 loss permits transcription of immunogenic repetitive elements and chronic viral mimicry activation …

Computational Sensitivity Evaluation Of Ultrasound Neuromodulation Resolution To Brain Tissue Sound Speed With Robust Beamforming, Boqiang Fan, Wayne Goodman, Sameer A Sheth, Richard R Bouchard, Behnaam Aazhang

Faculty, Staff and Student Publications

Low-intensity focused ultrasound (LIFU) neuromodulation requires precise targeting and high resolution enabled by phased array transducers and beamforming. However, focusing optimization usually relies on phantom measurements or simulations with inaccurate acoustic properties to degrade neuromodulation resolution. Therefore, this work analyzes the sensitivity of neuromodulation resolution, measured by off-target activation area (OTAA), to brain tissue sound speed. A Robust Optimal Resolution (ROR) beamforming method is proposed to minimize the worst-case OTAA with restricted sound speed inaccuracy and propagation information estimated with deviated sound speed. The propagation estimation model utilizes equivalent source method (ESM) to map sound field between different acoustic parameter …

Identifiability And Model Selection Frameworks For Models Of High-Grade Glioma Response To Chemoradiation, Khushi C Hiremath, Kenan Atakishi, Ernesto A B F Lima, Maguy Farhat, Bikash Panthi, Holly Langshaw, Mihir D Shanker, Wasif Talpur, Sara Thrower, Jodi Goldman, Caroline Chung, Thomas E Yankeelov, David A Hormuth Ii

Faculty, Staff and Student Publications

We have developed a family of biology-based mathematical models of high-grade glioma (HGG), capturing the key features of tumour growth and response to chemoradiation. We now seek to quantify the accuracy of parameter estimation and determine, when given a virtual patient cohort, which model was used to generate the tumours. In this way, we systematically test both the parameter and model identifiability. Virtual patients are generated from unique growth parameters whose growth dynamics are determined by the model family. We then assessed the ability to recover model parameters and select the model used to generate the tumour. We then evaluated …

Not Just A Health Kick: Time To Re-Evaluate The Role Of Smoothies In Glycaemic Response And Healthy Eating, Kathy M. Redfern, Thomas H. Walter, Gail A. Rees, Nathaniel J. Clark

School of Biomedical Sciences

In recent years, there has been a rise in popularity and subsequent consumption of both commercial and home-prepared smoothies due to the perceived health benefits of increasing fruit and vegetable intake in this way [1]. Under current public health guidance in the UK and Europe, smoothies are considered as fruit juices and should be limited to <150 ml/day and can only count towards one portion of fruit and vegetables. The current advice is largely based on the perceived ability of juiced fruits to increase the bioaccessibility of free sugars in the gut, resulting in faster uptake into the blood compared to whole foods and causing an elevated post prandial glycaemic response. However, there is a key difference between juiced fruits, such as orange juice, where the pulp of the fruit is removed, and smoothies, where the whole fruit is blended and consumed. The logic here is that by ingesting whole fruit, the digestive processes to break this down and release the equivalent free sugars is slower and results in a smaller glycaemic response. The issue is that recurrent elevated glycaemic response is a key risk factor for declining metabolic health, leading to conditions such as type 2 diabetes [2]. However, recent studies have suggested that consuming fruits in their blended form, such as smoothies, may not be detrimental for glycaemic control, and in some cases, may improve it by up to 57% [3, 4]. As adults in the UK do not currently eat enough fruit and vegetables, with only 33% of adults meeting the 5 a day recommendation [5], the potential for smoothies to increase fruit consumption whilst not adversely affecting metabolic health will require a change in public health advice.

Predicting The Distribution Of Mesophotic Coral Ecosystems In The Chagos Archipelago, Clara Diaz, Kerry L. Howell, Kyran P. Graves, Adam Bolton, Phil Hosegood, Edward Robinson, Nicola L. Foster

School of Biological and Marine Sciences

To support conservation efforts, accurate mapping of marine organism community’ distribution has become more critical than ever before. While previous mapping endeavours have primarily focused on easily accessible shallow-water habitats, there remains limited knowledge about the ecosystems lying beyond SCUBA diving depths, such as mesophotic coral ecosystems (MCEs, ~30–150 m). MCEs are important habitats from an ecological and conservation perspective, yet little is known about the environmental factors that shape these ecosystems and their distribution, particularly in the Indian Ocean region. The goals of this study are to (1) predict the spatial distribution and extent of distinct benthic communities and …

Unraveling The Complexities Of Myeloid-Derived Suppressor Cells In Inflammatory Bowel Disease, Yangzhuangzhuang Zhu, Siyan Cao

2020-Current year OA Pubs

Myeloid-derived suppressor cells (MDSCs) regulate immune responses in many pathological conditions, one of which is inflammatory bowel disease (IBD), an incurable chronic disorder of the digestive tract and beyond. The pathophysiology of IBD remains unclear, likely involving aberrant innate and adaptive immunity. Studies have reported altered population of MDSCs in patients with IBD. However, their distribution varies among patients and different preclinical models of IBD. The expansion and activation of MDSCs are likely driven by various stimuli during intestinal inflammation, but the in-depth mechanisms remain poorly understood. The role of MDSCs in the pathogenesis of IBD appears to be paradoxical. …

Metabolic Transitions In Embryos Of Artemia Franciscana: Regulation And Consequences For Oxidative Stress, Daniel Anthony Arabie

LSU Doctoral Dissertations

Embryos of Artemia franciscana survive harsh conditions in diapause and anoxia-induced quiescence for years by undergoing deep metabolic transitions. I investigated the relationship between phosphorylation of pyruvate dehydrogenase (PDH) and carbon flux to the tricarboxylic acid (TCA) cycle during metabolic depression. The difference in catalytic activity of the PDH complex (PDC) in maximally phosphorylated and dephosphorylated samples was 16.5-fold. Western blot analysis confirmed the changes in phosphorylation of PDH. Analysis of PDH expression in diapause and post-diapause embryos via phospho-PDH showed no significant differences. Investigation of post-diapause embryos under anoxia showed that phosphorylation of PDH decreased and activated the enzyme. …

Bone-Induced Her2 Promotes Secondary Metastasis In Hr+/Her2- Breast Cancer, Rahat Alam, Anna Reva, David G Edwards, Bree M Lege, Laura S Munoz-Arcos, Carolina Reduzzi, Swarnima Singh, Xiaoxin Hao, Yi-Hsuan Wu, Zeru Tian, Laura M Natalee, Gargi Damle, Deniz Demircioglu, Yixian Wang, Ling Wu, Elisabetta Molteni, Dan Hasson, Bora Lim, Zbigniew Gugala, Jerry E Chipuk, Julie E Lang, Joseph A Sparano, Chonghui Cheng, Massimo Cristofanilli, Han Xiao, Xiang H-F Zhang, Igor L Bado

Faculty, Staff and Students Publications

Bone metastases can disseminate to secondary sites and promote breast cancer progression creating additional clinical challenges. The mechanisms contributing to secondary metastasis are barely understood. Here, we evaluate the prediction power of Her2-expressing (Her2E) circulating tumor cells (CTCs) after analyzing over 13,000 CTCs from a cohort of 137 metastatic breast cancer (MBC) patients with initial HR+/Her2− status and employ preclinical models of bone metastasis (BM) to validate the role of Her2E CTCs in multi-organ metastases. While Her2 expression was higher in patients with bone metastasis, experimental analyses revealed that Her2E CTCs derived from bone lesions were more dependent on Her2 …

The First Record Of Alpiscorpius Idaeus (Yağmur & Tropea, 2017), Comb. N. From The Lesvos Island, Greece (Scorpiones: Euscorpiidae), Ersen A. Yağmur, Özgün Sipahioğlu

Euscorpius

The scorpion species Euscorpius idaeus Yağmur & Tropea, 2017, previously known from Mount Kazdağı in the Balıkesir and Çanakkale Provinces of Turkey, is reported for the first time from the Lesvos Island, Greece. In this study, it is transferred to the genus Alpiscorpius Gantenbein et al., 1999. Detailed illustrations of Alpiscorpius idaeus (Yağmur & Tropea, 2017), comb. n. from the Lesvos Island population are provided.

On The Motivations Of German Infantry During The World Wars, Charles J. Calcaterra

Grand Valley Journal of History

This article analyzes the experiences of standard German infantry between the First and Second World Wars. Particularly, it compares and contrasts the motivations of ordinary German civilians who entered into the German Army as well as their justifications, or means, for enduring such strenuous fighting. Notably, a sense of nationalistic duty toward the protection of Germany and adherence to the nation's cultural standards for masculinity urged many young men to join the military in both 1914 and 1939. This article also addresses how the devastating effects of the First World War led to a desensitization towards excessive violence in later …

Decolonizing National And Imperial Memories: From Postcolonial To Decolonial And Beyond, Jarula M.I. Wegner

Kritika Kultura

This article describes a discursive shift at the beginning of the twenty-first century in academic and public debates from postcolonial to decolonial critiques and asks what this means for the study of national and imperial memories. While some critics, like Robert J. C. Young, see this shift within postcolonial discourse, others, like Sylvia Wynter, believe that postcolonial theory itself needs to be decolonized. Regardless of whether one believes the shift is taking place within postcolonial studies or caused from outside, in any case it presents at least twelve complex transformations. While many of the characteristics hark back to a longer …

Transversal Symbiogenesis: Mapping A Nonlinear Postcolonial Future, Chun-Mei Chuang

Kritika Kultura

Gaia’s symbiotic imagery and the Anthropocene crisis characterize the early twenty-firstvcentury, shaping a historical consciousness where we are becoming Isabelle Stengers’sv“cosmopolitical idiots.” In this context, we practice “slowing down” and regeneration, always with historical specificities and intricate networks of relations. This paper reevaluates Aimé Césaire and Frantz Fanon’s vivid transcorporeal language, charged with the violent energy of resistance, through the lenses of symbiogenesis, metamorphosis, and hybridogenesis. I propose a nuanced understanding of postcoloniality that challenges normative notions of identity and violence, advocating for a nonlinear trans-species future. I emphasize the urgent need for a planetary postcolonial turn that embraces hybridity, …

Inactivation Of E. Faecium Nrrl B-2354 In Whole Black Pepper By Fluidization With Hydrogen Peroxide Vapor, Daniela Segura

Department of Food Science and Technology: Master of Science with Project Option

This study evaluated Enterococcus faecium NRRL B-2354 as a surrogate for Salmonella inactivation in black peppercorns treated with hydrogen peroxide (HP) vapor via fluidization. The selected parameter for dwell temperature was 60ºC for 60 minutes. The reduction of both Salmonella and E. faecium, along with changes in water activity, color, and residual hydrogen peroxide, were measured before, immediately after treatment and at 24 and 48 hours post-treatment. Results showed that E. faecium exhibited a significantly greater reduction (4.63 ± 0.55 log CFU/g) compared to Salmonella (2.94 ± 0.16 log CFU/g) (p < 0.05), making E. faecium unsuitable as …

Cal Poly Humboldt Library Digest, April 2025, Cal Poly Humboldt Library

Library Publications

No abstract provided.

Ceker: A Generalizable Llm Framework For Literature Analysis With A Case Study In Unikernel Security, Alex Wollman, John Hastings

Research & Publications

Literature reviews are a critical component of formulating and justifying new research, but are a manual and often time-consuming process. This research introduces a novel, generalizable approach to literature analysis called CEKER which uses a three-step process to streamline the collection of literature, the extraction of key insights, and the summarized analysis of key trends and gaps. Leveraging Large Language Models (LLMs), this methodology represents a significant shift from traditional manual literature reviews, offering a scalable, flexible, and repeatable approach that can be applied across diverse research domains. A case study on unikernel security illustrates CEKER's ability to generate novel …

Texas Institute For The Preservation Of History And Culture Newsletter - April 2025, Texas Institute For The Preservation Of History And Culture

Newsletter Collections

No abstract provided.

Association Of Dmd Gene Variant Classes With Motor Outcomes In A Drug Registration Clinical Trial Setting, Yuan Fang, Utkarsh J. Dang, Katherine I. Illei, Paula Clemens, Eric P. Hoffman, Cinrg, Vision Dmd Investigators

Pharmacy Faculty Scholarship

Background and Objectives: Duchenne muscular dystrophy (DMD) is caused by pathogenic variants of the DMD gene, leading to the loss of dystrophin. Clinical variability in DMD can complicate interpretation of interventional data in clinical trials. One source of clinical variability is allelic heterogeneity (different pathogenic variants with different effects on dystrophin protein expression). We sought to determine whether gene variant classes in clinical trial participants potentially affect clinical trial data interpretation. Methods: We analyzed 186 vamorolone trial participants with DMD (VBP15-002/003; VBP15-004) who were 4 to steroid-naïve at baseline. We stratified participants into gene variant classes by either variant location …