Digital Commons Network^™

Video Tracking As An Effective High Throughput Method For Mtbi Detection, Julie Mcintyre, Julie A. Semon

Miners Solving for Tomorrow Research Conference

No abstract provided.

Coupled Time-Dependent Stokes - Darcy Model With Beavers–Joseph–Saffman–Jones Interface Boundary Condition, Yafang Hei, Xiaoming He

Miners Solving for Tomorrow Research Conference

No abstract provided.

Maldi-Mass Spectrometry Imaging To Investigate Distribution Of Per- And Polyfluoroalkyl Substances In Exposed Poplar Tissues, Tonglin Zhou, Varuni Abhayarayne, Joseph Akor, Honglan Shi, Paul Ki-Souk Nam, Joel Gerard Burken, John Yang

Miners Solving for Tomorrow Research Conference

No abstract provided.

Analysis Of Chromatin Accessibility Changes In Endothelial Cells Exposed To Plastic Contaminants, Mikhail Y. Salnikov, Carly Boye, David B. Witonsky, Gabrielle Garlicki, Adnan Alazizi, Francesca Luca, Roger Pique-Regi

Medical Student Research Symposium

Degradation products from everyday plastic products are known to bioaccumulate and have also been shown to contaminate drinking water and food sources. BPA and phthalates are endocrine disrupting chemicals and plastic components that have previously been associated with endothelial cell dysfunction, atherosclerotic and other adverse cardiovascular events. However, there is a limited understanding of the mechanisms underlying these associations, such as genome-wide chromatin accessibility changes in endothelial cells exposed to these compounds. The purpose of this study is to explore genome-wide changes in chromatin accessibility associated with plastic exposure, as well as the discovery of transcription factor binding motifs dysregulated …

Characterizing Kmt2d In Endometrial Cancer, Katherine R. Davanzo

Medical Student Research Symposium

Endometrial cancer is rising in incidence in the United States, notably among premenopausal women. This increase and the trend of delayed childbearing warrant the need for further advancement in fertility-sparing treatment for endometrial cancer. A gene left widely unexplored in its possible clinical utility as a target for fertility-sparing treatment is KMT2D, a lysine-specific methyltransferase and tumor suppressor. Preliminary gene set enrichment analysis on a 12Z endometriotic epithelial cell line identified TIMP3 as a gene that is possibly regulated by KMT2D expression. TIMP3 encodes an irreversible inhibitor of matrix metalloproteinases (MMPs), a well-recognized class of proteins as contributing to the …

Skin Of Color Representation In Biologic Advertisements For Psoriasis And Psoriatic Arthritis, Grace Doakes, Sydney Martin, Melissa Baithey, Julia Riley, Kelsey Flood, Rithu Srikantha

Medical Student Research Symposium

Skin of color (SoC) patients with psoriasis experience more severe disease, lower quality of life, and increased psoriasis-related hospitalizations compared to non-SoC counterparts (1-2). SoC patients with psoriasis demonstrate decreased familiarity with biologic medications (3-4) , which could lead to undertreatment and greater disease burden. In light of previous findings indicating inadequate SoC representation in dermatologic direct-to-consumer (DTC) advertising, we compared skin tone representation in patient-facing materials for 13 biologics FDA-approved for psoriasis and psoriatic arthritis (PsA) on pharmaceutical DTC advertising websites from July 20, 2023 to August 20, 2023. Images of 331 people, excluding videos, were analyzed via Fitzpatrick …

Multi-Omics Analysis Reveals Cmtr1 Upregulation In Cancer And Roles In Ribosomal Protein Gene Expression And Tumor Growth, Ion John Campeanu, Yuanyuan Jiang, Hilda Afisllari, Sijana Dzinic, Lisa Polin, Zeng-Quan Yang

Medical Student Research Symposium

Background: CMTR1 (cap methyltransferase 1), a key nuclear mRNA cap methyltransferase, catalyzes 2'-O-methylation of the first transcribed nucleotide, a critical step in mRNA cap formation. Previous studies have implicated CMTR1 in embryonic stem cell differentiation and immune responses during viral infection; however, its role in cancer biology remains largely unexplored. This study aims to elucidate CMTR1's function in cancer progression and evaluate its potential as a novel therapeutic target across multiple cancer types.

Methods: We conducted a comprehensive multi-omics analysis of CMTR1 across various human cancers using TCGA and CPTAC datasets. Functional studies were performed using CRISPR-mediated knockout and …

Implications Of Glyphosate-Based Herbicides On The Female Reproductive System And Reproductive Outcomes, Alexandra Stone, Olivia G. Camp Ms, David Bai Md, Awoniyi Awonuga, Husam M. Abu-Soud

Medical Student Research Symposium

Background

Glyphosate-based herbicides (GBHs) are the most widely used herbicides in the United States, accounting for 19% of estimated global use. Although the Environmental Protection Agency has reaffirmed that the active ingredient glyphosate (GLY) is safe for humans, recent studies on exposure have suggested an association with cancer, metabolic disorders, endocrine disruption and infertility, and Alzheimer’s and Parkinson’s disease. Recently, we have shown that GLY exposure deteriorates metaphase II oocyte quality through zinc deficiency, ROS accumulation, and chromosome disruption. In this work, we review the mechanisms of GLY toxicity in the female reproductive tract and discuss the potential clinical implications …

Androgen Hormones Regulate The Production On The Pain-Inducing Inflammatory Molecule Il-1Β In A Mouse Model Of Inflammatory Pain, Hariharan Ramakrishnan, Geoffroy Laumet, Jaewon Sim

Medical Student Research Symposium

Chronic pain prevalence varies between sexes with a higher incidence and duration reported in women compared to men. This disparity suggests that biological factors, such as sexual hormones, may influence pain perception and development. Among the key players in pain mechanisms, interleukin-1 beta (IL-1β), an inflammatory molecule, has been identified to activate neurons involved in pain sensation. This study explores the hypothesis that sexual hormones, particularly androgens, regulate IL-1β production in inflamed tissues, thereby influencing pain responses. To investigate this, we induced inflammatory pain in male and female mice using Complete Freund’s Adjuvant (CFA), injected into the hind paw. To …

The Role Of Age, Experience, And Physical Fitness In Technical Performance In Karate: An Observational Analysis, Rui Miguel Silva, Joaquim Ferreira, Georgian Badicu, Jarosław Muracki, Beata Pożarowszczyk-Kuczko, Adam Kawczyński

Baltic Journal of Health and Physical Activity

Background: This study aimed to investigate the relationships between age, experience, anthropometric measures, physical fitness, and the quality of technical performance in karate practitioners. We conducted an observational cross-sectional study with 53 federated karate athletes, aged 5 to 55, affiliated with the Youth Karate Association Portugal. The participants were divided into age and experience groups to assess differences in anthropometric measures (body mass, height, BMI) and physical fitness (strength, power, flexibility). The technical performance of four specific karate techniques – kizami, gyaku zuki, mawashi geri, and ura mawashi geri – was evaluated using a custom-designed technical evaluation …

Shellfish Regulation: Conservation And Discrimination, Maine Law Review

Maine Law Review

The economy of many coastal states depends heavily upon the shellfish industry. Shellfish such as lobsters and clams are an especially important marine resource for these states. In recent years, however, the supply of shellfish has experienced substantial declines. State laws that permit the harvesting of lobsters prior to sexual maturity, for example, have made the lobster industry dependent on the yearly additions to the lobster supply. The increasing demands for shellfish as well as the pollution of areas such as coastal clamflats have also contributed to the serious depletion of the shellfish resources in many areas. Despite the possible …

Boundary Delimitation In The Economic Zone: The Gulf Of Maine Dispute, Maine Law Review

Maine Law Review

In an ideal world of abundant natural resources, homogeneously distributed among nations, the issue of marine boundary delimitation would have little significance within the international community. However, the realities of randomly concentrated and limited resources, complicated by the political geography of the oceans, have made maritime boundary delimitation a crucial international issue. In a world of more than 130 coastal nations, the determination of standards for allocation of living and non-living ocean resources within the fertile offshore areas has become an issue of widespread economic importance. Nonetheless, the international community has developed few concrete and specific rules for marine boundary …

The Fishery Conservation And Management Act Of 1976: State Regulation Of Fishing Beyond The Territorial Sea, Maine Law Review

Maine Law Review

Historically, international law has recognized the sovereignty of coastal nations within the three-mile contiguous territorial sea. Although modem international practice has expanded the breadth of the territorial sea to twelve miles or more, the traditional three-mile zone retains a special significance within the scheme of domestic United States marine law. Under the federal scheme of marine resource jurisdiction, authority within the three-mile zone has been allocated to the coastal states while the federal government has exercised near-exclusive jurisdiction over marine zones seaward of the territorial sea boundary. However, this bifurcated jurisdiction scheme has failed to provide effective conservation and management …

Safety Study Of Polyunsaturated Fatty Acids Extracted From New Zealand Green Lipped Mussel And Krill On Hematology And Blood Chemistry Profiles Of Healthy Dogs And Cats, Uttra Jamikorn, Panumas Kongpanna

The Thai Journal of Veterinary Medicine

New Zealand green-lipped mussel (Perna canaliculus) is a shellfish with a green shell containing many types of fatty acids, especially polyunsaturated fatty acids (PUFAs). The aim of the present study was to investigate the safety of dietary PUFAs supplementation on blood hematology, chemistry and coagulogram pancreatic enzymes in dogs and cats. Twelve healthy beagle dogs and healthy mature cats were used in these studies. Complete randomized block and triplicate 4×4 Latin square designs were used for these dog and cat safety studies, respectively. Experimental diets composed of sham control (0X) and 3 treatment groups, including 1X, 3X, and …

The Importance Of Motivation And Self-Concept For Predicting Performance In Service Mathematics Modules: Replicating And Extending Previous Findings, Catherine Palmer, Maryna Lishchynska, Declan O’Connor, Seán Lacey

Department of Mathematics Publications

Students’ difficulties and lower-than-desired mathematics performance in higher education have been the focus of educational research and practice for a period of time. In a recent study by Lishchynska et al. (2023), learners’ motivation, dispositions towards mathematics and learning strategies were examined as factors potentially affecting performance in service mathematics modules. The main objectives of this study were to replicate the findings of Lishchynska et al. (2023) with a new student cohort; determine if self-concept is a significant contributortomathematicsperformance;andexploreifmathematicalbackgroundremainsan important predictor of mathematics performance for students as they migrate from first year to final year of study. A survey of …

Challenges Of Digital World Based On Ulsi And Tft Technologies Involving New Neuromorphic Approaches, Olivier Bonnaud

2025 International Conference on Semiconductor Technology for Ultra Large-Scale Integrated Circuits and Thin Film Transistors (ULSIC VS TFT 9)

Please click Additional Files below to see the full abstract

April 2025 General Education Council Minutes, University Of Nebraska At Kearney General Education Council

General Education Council

No abstract provided.

Atlantic Sharpnose Shark (Rhizoprionodon Terraenovae) Neurocranium, Michelle Bassali, David Kerstetter, Ema Nagel

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Preparation , Characterization And Stability Of Chitosan/Gum Arabic Nano-Emulsion, Kang Yuzhao, Tao Shuotong, Deng Sihui, Zhong Saiyi, Li Rui

Food and Machinery

［Objective］ To investigate the stability of nano -emulsion at different pH levels and its storage stability,and to explore their use in curcumin encapsulation.［Methods］ Nano -emulsion was prepared using the ion complexation method.The amounts of chitosan (CS) and gum Arabic (GA) were optimized based on particle size and Zeta potential.Fourier transform infrared spectroscopy (FTIR ) was used to analyze intermolecular interactions,while scanning electron microscopy (SEM ) was employed to observe the micro -morphology of CS/GA nano -emulsion.The encapsulation efficiency of curcumin was determined by spectrophotometry.［Results］ When the mass concentrations of CS and GA were 2.5 mg/mL and 1.5 mg/mL,respectively,the prepared nano …

Rapid Determination Of Dimethyl Fumarate In Beverages By Dispersed Liquid-Liquid Microextraction With Ultrasound-Assisted And High Performance Liquid Chromatography, Jiang Fangjun, Liang Feng, Feng Yalong, Li Qiuyi, Ding Fanglin, Zhang Zhaohui

Food and Machinery

［Objective］ To establish a rapid detecting method for the determination of dimethyl fumarate in beverages by ultrasound -assisted dispersive liquid -liquid micro -extraction coupled with high performance liquid chromatography.［Methods］ The beverage samples were spiked with extractant and dispersant,extracted by ultrasonic extraction,centrifuged and determined by high performance liquid chromatography.［Results］ The optimal microextraction conditions were 100 μL of chloroform as extractant,300 μL of acetone as dispersant,and a sonication time of 4 min.Under the optimal extraction conditions,dimethyl fumarate had a linear range of 0.1~100.0 μg/mL with a detection limit of 0.02 μg/L.The relative standard deviation (RSD ) of the method was less than …

Preparation , Structural Characterization And Antioxidant Activity Of Selenium Nanoparticles Decorated By Atrina Pectinata Polysaccharides, Zhang Yin, Nan Zhiguang, Lu Congfei, Wu Yuxin

Food and Machinery

［Objective］ This study aimed to optimize the preparation process of selenium nanoparticles stabilized by Atrina pectinata polysaccharides (APPS -SeNPs ),evaluate their antioxidant activity,and explore their potential as a functional food additive.［Methods］ Selenium nanoparticles were prepared using the sodium selenite reduction method with A.pectinata polysaccharides as stabilizer.The preparation process was optimized using single -factor experiments and response surface methodology (RSM ).The particle size,zeta potential and selenium content were measured,and the nanoscale structure was analyzed.Antioxidant activity was evaluated by assessing the scavenging effects on DPPH and hydroxyl (OH) radicals.Four factors influencing particle size -molar ratio of vitamin C to sodium selenite,reaction temperature,reaction …

Effects Of Pulsed Light Treatment On Storage Quality Of Semidry Noodles In Bubble Green, Ye Ruxiao, Jiang Lei, Lu Qingyun, Jiang Xiujun, Liu Yadong

Food and Machinery

［Objective］ This study aimed to improve the on the storage quality of bubble green semidry noodles.［Methods］ By adjusting the treatment pulse energy,pulse distance,and storage time of bubble green semidry noodles,the effects of these factors on the storage quality of bubble green semidry noodles were comprehensively analyzed.By comparing indicators such as microbial content,color difference,chlorophyll content,texture characteristics,moisture distribution,and protein secondary structure,the optimal parameters for pulsed light treatment of bubble green semidry noodles were determined.［Results］ The optimal parameters for pulsed light treatment of bubble green semidry noodles were as followed:pulse energy of 900 J,pulse frequency of 20 times,and pulse distance of 5 cm.Under …

Optimization Of Chitosan-Soy Protein Isolate Composite Film Fabrication And Its Preservation Effect On Mangoes, Guo Peifeng, Wu Yuwei, Xie Xingchan, Xu Ying, Wang Rui, Zeng Xin ’An

Food and Machinery

［Objective］ To optimize the fabrication process of chitosan (CS) and soy protein isolate (SPI) composite films,enhance their comprehensive performance,and evaluate their impact on the preservation of mangoes.［Methods］ CS and SPI were used as the film -forming substrates.The tensile strength,elongation at break,water vapor transmission rate,oxygen permeability,carbon dioxide permeability,and light transmittance of the composite film were used as evaluation indexes.The K-value of the composite film's comprehensive performance was calculated using fuzzy comprehensive evaluation.Response surface analysis was applied to optimize the formulation of the CS -SPI composite film,with the K-value as the response variable.［Results］ The optimal preparation conditions for the CS-SPI composite film …

Egg Appearance Detection Based On Improved Cnn And Hierarchical Svm, Yao Wanpeng, Zhang Lingxiao, Zhao Xiaofeng, Wang Feicheng

Food and Machinery

［Objective］ To achieve fine classification of eggs and improve the accuracy of egg appearance detection.［Methods］ An egg appearance detection scheme based on improved convolutional neural network (CNN ) and hierarchical support vector machine (SVM ) was proposed.① Egg images with different orientations and appearances were captured using an egg machine vision image acquisition device,and image enhancement techniques were applied to expand the egg image database.② An improved Coati optimization algorithm (COA ) and fuzzy C -means (FCM ) clustering algorithm were designed,based on which the structure and hyperparameters of the CNN model were optimized to enhance its generalization ability.The optimized …

Composition , Structure And Comparison Of In Vitro Hypoglycaemic And Hypolipidemic Activities Of Two Polysaccharides Extracted From Noni Fruit, Li Honghang, Wu Xiaoyong, Liang Jian, Wang Zhijiang

Food and Machinery

［Objective］ This paper aims to characterize the composition and structure of two polysaccharides extracted from Noni fruit and compare their in vitro hypoglycaemic and hypolipidemic activities.［Methods］ Two polysaccharides,NFP -30 and NFP -80,were extracted and isolated from Noni fruit by water extraction and ethanol precipitation method.They were then characterized by means of physicochemical analyses,spectral analyses,and scanning electron microscopy observations,and their in vitro hypoglycaemic and hypolipidemic activities were evaluated by the determination of the inhibition rates of α-glucosidase and pancreatic lipase.［Results］ The neutral sugar contents of NFP -30 and NFP -80 were (50.73±1.32)% and (42.30±1.11)%,respectively,and the glucuronic acid contents were (61.48±0.40)% and …

Preparation Technology And Antioxidant Activity Of Exopolysaccharide From Sulfated Porphyridium Aerugineum, Duan Dongjie, Zhang Wei, Sui Chengbo, Zhang Hao, Zhang Guodong

Food and Machinery

［Objective］ To improve the biological activity and application range of Porphyridium aerugineum exopolysaccharide (EPS).［Methods］ EPS was modified using the concentrated sulfuric acid method,with the degree of sulfation as the indicator.The preparation process of sulfated P.aerugineum exopolysaccharide (S-EPS) was optimized using response surface methodology.The physicochemical properties of S -EPS were also determined.［Results］ The optimal conditions were a reaction time of 6 h,a reaction temperature of 26 ℃,and a mass ratio of ammonium sulfate to EPS of 4∶5.Under these conditions,the degree of substitution was 0.807 5±0.008 7.Infrared analysis confirmed that EPS was successfully sulfated.Thermogravimetric analysis showed that the thermal stability of S …

Anti-Fatigue Effect Of Food-Derived Compound Ginseng Aqueous Extracts, Xiong Wuqing, Ma Xiuping, Guo Jiangtao, Bai Zhiwen, Luo Shixi

Food and Machinery

［Objective］ To investigate the anti -fatigue effect of compound aqueous extracts of Ginseng Radix et Rhizoma,Polygonati Rhizoma,Polygonati Odorati Rhizoma,and Citri Reticulatae Pericarpium in mice.［Methods］ The experiment included a blank control group,a positive control group (Rhodiola rosea capsules,0.70 g/kg ),and low,medium,and high dose groups of compound ginseng aqueous extracts (1.56,3.30,and 6.60 g/kg,respectively ),which were administered by gavage for 30 days.The anti -fatigue effect was evaluated using the weight -bearing exhaustion swimming test and by measuring biochemical markers,including hepatic glycogen,blood lactate,and blood urea nitrogen.［Results］ Compared with the blank control group,the compound ginseng aqueous extracts had no significant effect on the normal weight …

Optimization Of Browning Control Process In Chestnut Processing And Analysis Of Its Indicators, Gao Chunhui, Su Yu, Liu Shiyu, Xu Zhixiang

Food and Machinery

［Objective］ To address the browning issue during chestnut processing.［Methods］ Taishan chestnuts were used as the raw materials.The color protection process conditions were determined through a single -factor experiment.Three factors -melatonin concentration,malic acid mass fraction,and citric acid mass fraction -were selected for a response surface optimization experiment to determine the optimal concentrations of the color protection agents.The effects of different treatments on the physicochemical properties of the chestnuts were assessed by measuring the total phenol content,reducing sugar content,ascorbic acid content,malondialdehyde content,DPPH and ABTS free radical scavenging rates,and water content.［Results］ The optimal color protection process conditions were determined as follows:soaking in the …

Research Progress On Immunoassay Technology Based On Nanoenzyme Labeling In Detection Of Food Safety, Liu Ziyang, Hu Gaoshuang, Hao Jianxiong, Wang Chenyu, Shi Yingying, Yu Qingxiu

Food and Machinery

Food safety has become a hot topic of widespread concern across society,and efficient,sensitive detection technologies are essential tools for ensuring food safety.Immunoassay is the gold standard for high -sensitivity detection of biochemical targets,providing an excellent platform for the detection of food contaminants.In recent years,it has gradually been applied to various food safety detection methods.Nanoenzymes,as synthetic analogs of natural enzymes,offer advantages such as good stability and high sensitivity,meeting the demands of rapid detection methods under increasingly stringent detection limits.This article reviews the detection principles and advantages of immunoassay technology based on nanoenzyme labeling,discussing its applications in different areas of food safety …

Advances In Research On Application Mechanisms Of Small-Molecule Emulsifiers In Ice Cream, Chen Ling, Li Lijun, Xu Haijun, Jin Huajin, Zhong Fang, Xia Yixun, Kang Jingran, Wu Juan, Wang Caiyun

Food and Machinery

Ice cream,a complex whipped and aerated colloidal system,requires an appropriate degree of fat globule destabilization during its production to form a specific structure.Small -molecule emulsifiers can regulate the degree of fat destabilization by adsorbing onto the fat globule surface,reducing surface tension,and competing with proteins for positions at the oil -water interface.At the same time,they can promote the dispersion of fat particles or form a protective film at the oil -water interface,thereby influencing fat crystallization.Moreover,small -molecule emulsifiers can act as template molecules,guiding the assembly of fats into various specific shapes,such as spherical,rod-like,and lamellar forms,and adjusting the size and morphology of fat …