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Articles 35851 - 35880 of 830593
Full-Text Articles in Entire DC Network
Commencement: Conferral Of Baccalaureate Degrees May 21, 2025, New Jersey Institute Of Technology
Commencement: Conferral Of Baccalaureate Degrees May 21, 2025, New Jersey Institute Of Technology
Commencement Programs
Program for the commencement conferral of Baccalaureate degrees. The ceremony took place on Wednesday, May 21, 2025.
Characterization Of Immunogenicity Of Hiv Mrna Vaccine In Humanized Mice, Omoyeni Precious Adejare
Characterization Of Immunogenicity Of Hiv Mrna Vaccine In Humanized Mice, Omoyeni Precious Adejare
Biotechnology Theses
Human Immunodeficiency Virus (HIV) remains a leading global cause of mortality. Despite decades of research, a definitive cure or an effective vaccine for HIV infection has yet to be discovered. The major target for HIV vaccine development is the envelope (Env) trimeric protein that is responsible for host cell attachment and fusion. This comprises gp120 and the transmembrane gp41. Gp140, a truncated form of gp160(full envelope trimer) lacks the transmembrane and cytoplasmic domains of gp41, closely mimics the native HIV envelope has been shown to enhance the induction of broadly neutralizing antibodies (BnAbs) when used as protein vaccine in previous …
Exploring Gender Differences And Psychosocial Mechanisms In Heterosexist And Cisgenderist Attitudes Across The U.S. And India, Benjamin Gronich
Exploring Gender Differences And Psychosocial Mechanisms In Heterosexist And Cisgenderist Attitudes Across The U.S. And India, Benjamin Gronich
ETD Collection
No abstract provided.
Correlates Of Internalized Weight Bias In An Ethnically Diverse College Sample, Amanda Cipolla
Correlates Of Internalized Weight Bias In An Ethnically Diverse College Sample, Amanda Cipolla
Psychology ETDs
Understanding factors related to internalized weight bias (IWB), particularly among diverse populations, is an important avenue of research to inform interventions aimed at reducing IWB. This study surveyed college students (n = 319) about their body image, social media use, and culture. ANOVA, multiple regression, and hierarchical regressions were used to analyze data. Overall, body image flexibility emerged as a strongly negatively related to IWB, indicating potentially protective qualities. Physical appearance comparison, objectified body consciousness, and BMI emerged as maladaptive correlates. Findings related to social media were more complicated, with appearance related social media consciousness as an important negative correlate, …
Influence Of Acid-Catalyzed Dehydration And Pressure On Woody Biomass Carbonization: Exploring Carbon Yield, Heteroatom Functionalities, And Biochar Atomistic Structure, Valentina Sierra, Robert J. Macias, Jonathan P. Mathews, Vincent Carré, Sébastien L Eclerc, Alice Budai, Farid Chejne, Jimena Castro-Gutierrez, Vanessa Fierro, Manuel Garcia-Perez
Influence Of Acid-Catalyzed Dehydration And Pressure On Woody Biomass Carbonization: Exploring Carbon Yield, Heteroatom Functionalities, And Biochar Atomistic Structure, Valentina Sierra, Robert J. Macias, Jonathan P. Mathews, Vincent Carré, Sébastien L Eclerc, Alice Budai, Farid Chejne, Jimena Castro-Gutierrez, Vanessa Fierro, Manuel Garcia-Perez
Bio-Char IV
Please click Additional Files below to see the full abstract
Biochar As Biofertilizer For The Cultivation Of Strawberries, Silvia Fiore, Ilaria Orlandella, Marco Piras, Elena Belcore, Kyra Nancie Smith, Franco Berruti
Biochar As Biofertilizer For The Cultivation Of Strawberries, Silvia Fiore, Ilaria Orlandella, Marco Piras, Elena Belcore, Kyra Nancie Smith, Franco Berruti
Bio-Char IV
Please click Additional Files below to see the full abstract
The Future Of The Us Marine Seafloor And Subseafloor Sampling Capabilities, Future 2024 Pi-Team, Olga Libman‐Roshal
The Future Of The Us Marine Seafloor And Subseafloor Sampling Capabilities, Future 2024 Pi-Team, Olga Libman‐Roshal
Department of Earth and Environmental Studies Faculty Scholarship and Creative Works
Recent changes in US oceanographic assets are impacting scientists' ability to access seafloor and sub-seafloor materials and thus constraining progress on science critical for societal needs. Here we identify national infrastructure needs to address critical science questions. This commentary reports on community-driven discussions that took place during the 3-day FUTURE of US Seafloor Sampling Capabilities 2024 Workshop, which used an “all-hands-on-deck” approach to assess seafloor and sub-seafloor sampling requirements of a broad range of scientific objectives, focusing on capabilities that could be supported through the US Academic Research Fleet (US-ARF) now or in the near future. Cross-cutting issues identified …
Development Of Stem-Based Virtual Microscope Module In Fundamental Geology Course, Bigharta Bekti Susetyo, Dipo Caesario, Yulia Hanoselina, Helfia Edial, Intan Lestari Mulyaning Tyas, Ahmad Syauqi Hidayatillah, Alfyananda Kurnia Putra, Salem Amer Sayma
Development Of Stem-Based Virtual Microscope Module In Fundamental Geology Course, Bigharta Bekti Susetyo, Dipo Caesario, Yulia Hanoselina, Helfia Edial, Intan Lestari Mulyaning Tyas, Ahmad Syauqi Hidayatillah, Alfyananda Kurnia Putra, Salem Amer Sayma
Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi
This research aims to develop a STEM-based virtual microscope module. It follows a 4D development model, comprising define, design, develop, and disseminate stages. Interview were employed as the primary data collection techniques. The data analysis techniques utilized both descriptive and quantitative methods. The feasibility of developed module validated by expert validators in material content, language, and learning design. Field testing was conducted with Geography Education Study Program students from Class of 2023 in the Fundamental Geology Course. The STEM-based virtual microscope module was deemed suitable for learning activities, receiving validation scores in the "good" category with minor revisions required. Student …
Explaining The Satisfaction Of The Religious Tourist: The Case Of Maimonides In The City Of Cordoba, César Mora Márquez, Angelo Puccia
Explaining The Satisfaction Of The Religious Tourist: The Case Of Maimonides In The City Of Cordoba, César Mora Márquez, Angelo Puccia
International Journal of Religious Tourism and Pilgrimage
Tourism was one of the most severely affected sectors by the Covid-19 pandemic. Even religious tourism, traditionally less susceptible to market fluctuations, is now compelled to adopt innovative strategies in response to these effects. This article analyses the satisfaction of religious tourism, specifically its relationship with the figure of Maimonides, who is considered to be an important religious thinker and is included within the Pantheon database of the Massachusetts Institute of Technology (MIT). A questionnaire was distributed and completed by 720 tourists in the city of Cordoba, Spain, which has close links to Maimonides. The findings indicated that the spirituality …
Miracles Have Subjective Meaning For Religious Travellers, Even If They Are Not Supernatural, Stephen F. Haller
Miracles Have Subjective Meaning For Religious Travellers, Even If They Are Not Supernatural, Stephen F. Haller
International Journal of Religious Tourism and Pilgrimage
Miracles still play a role in religious tourism even though it is impossible to distinguish them as divinely inspired, rather than derived from ‘mere’ psychological causes. One might ask whether it matters to a religious tourist or pilgrim that the adoption of a religious attitude to the mysteries of miracles is not grounded in religious belief in the supernatural. Are religious tourists and pilgrims not just inventing comforting illusions in wilful ignorance?
This philosophical paper will relate a few examples of miracles; and explain how the experience of miracles is a subjective experience, and not an objective belief in a …
The Unicorn And Christ – Metamorphosis And Symbology, Luis Mendonça De Carvalho, Francisca Maria Fernandes, Maria Fátima Nunes, Ana Maria Costa, Paula Nozes, Ana Paula Figueira
The Unicorn And Christ – Metamorphosis And Symbology, Luis Mendonça De Carvalho, Francisca Maria Fernandes, Maria Fátima Nunes, Ana Maria Costa, Paula Nozes, Ana Paula Figueira
International Journal of Religious Tourism and Pilgrimage
The unicorn is a legendary chimaera that, for centuries, has been present in the mindset of Euro-Mediterranean cultures. Although its morphological description changed, tradition identifies it as an animal like a horse, albeit smaller and with a spiralling horn on its head pointing forward. The unicorn has been known since Antiquity, with references by authors such as Ctesias and Pliny. However, its relevance for medieval Europeans began with the Biblical references to this animal in several Old Testament verses. These verses gave legitimacy to the unicorn, and it was accepted as a tangible animal. During the Middle Ages and early …
School-Based Mental Health Practice: The Impact Of Physical Activity On Depression, Nafees Alam, Joy Krug
School-Based Mental Health Practice: The Impact Of Physical Activity On Depression, Nafees Alam, Joy Krug
Social Work Faculty Publications
The relationship between physical and mental health has long been theorized to be profoundly important in understanding human behavior and development. This article aims specifically to highlight the state of existing research about the relationship between physical activity and the state of depression. Studies across the nation, summarized here, have found that healthy physical activity levels generally correlate with health within the mental and emotional arenas. Despite the abundance of existing literature on this topic, research remains scarce on the longitudinal effects of physical activity beginning with pre-puberty children into adulthood. Physical activity is a relatively cheap and non-harmful lifestyle …
Optimizing Warfarin Management In Cardiovascular Care, Tessa A. Martinez
Optimizing Warfarin Management In Cardiovascular Care, Tessa A. Martinez
Doctor of Nursing Practice Final Manuscripts
Background: Maintaining a therapeutic International Normalized Ratio (INR) is essential to reduce bleeding and thromboembolic risks in patients on warfarin therapy. In a rural outpatient cardiac clinic serving a predominantly underserved population, many patients face financial and access barriers that preclude the use of newer non-vitamin K antagonist oral anticoagulants (NOACs). Patients with atrial fibrillation (AF) or mechanical valve replacements who rely on warfarin require consistent monitoring and management, which can be challenging in settings with limited resources and staffing.
Purpose: The purpose of this evidence-based pilot project was to improve therapeutic INR outcomes through the implementation of a standardized …
Reducing Surgery For Pediatric Posttonsillectomy Hemorrhage Using Tranexamic Acid: A Quality Improvement Initiative, Laura A. Petrauskas, Janavi Sethurathnam, Ansley J. Kunnath, Rahul K. Sharma, John Ceremsak, Ryan H. Belcher, James D. Phillips, Jay A. Werkhaven, Amy S. Whigham, Lyndy J. Wilcox, Christopher T. Wootten, Frank W. Virgin, Jason S. Park
Reducing Surgery For Pediatric Posttonsillectomy Hemorrhage Using Tranexamic Acid: A Quality Improvement Initiative, Laura A. Petrauskas, Janavi Sethurathnam, Ansley J. Kunnath, Rahul K. Sharma, John Ceremsak, Ryan H. Belcher, James D. Phillips, Jay A. Werkhaven, Amy S. Whigham, Lyndy J. Wilcox, Christopher T. Wootten, Frank W. Virgin, Jason S. Park
School of Medicine Faculty Publications
Objective: Evaluate the use of tranexamic acid (TXA) and observation as a management option for pediatric patients presenting with posttonsillectomy hemorrhage (PTH). Study Design: Retrospective analysis of a prospectively implemented quality improvement initiative with a historical control comparison group. Setting: Tertiary children's hospital. Methods: Patients < 18 years of age who underwent adenotonsillectomy (AT) and returned to the Emergency Department for PTH were included. Patients who were stable without large volume or active bleeding were given intravenous TXA and admitted for overnight observation. Data were compared in a before-and-after analysis: preprotocol (April 2022 to March 2023) versus postprotocol (April 2023 to March 2024). For cost-effectiveness analysis, we analyzed aggregated claims data from a commercial claims database. Results: Preprotocol 1800 adenotonsillectomies were performed, and 40 procedures were performed for control of hemorrhage (2.2 per 100 AT). Postprotocol 2356 adenotonsillectomies were performed, and 30 procedures were performed to control hemorrhage (1.3 per 100 AT) showing a significant reduction in return to the operating room (relative risk [RR] = 0.59, 95% confidence interval [CI] [0.358, 0.916], P-value.020). There were no reported adverse events attributable to TXA. An estimated 21 surgeries were avoided, and 26 additional patients were observed in the hospital during the postprotocol period, for an estimated net cost savings of $174,970. Conclusion: The implementation of a standardized TXA protocol significantly reduced the need for return to the operating room for PTH in pediatric patients, without complications and with net cost savings to the health care system.
Woodchip-Based Permeable Reactive Barriers For Groundwater Nitrogen Removal: Design Optimization To Minimize Greenhouse Gas Release Informed By Experimental Studies And Reaction-Transport Modeling, Jing-An Lin Phd
Electronic Dissertations and Theses, 2010-current
Submarine groundwater discharge of legacy nitrogen can significantly contribute to coastal eutrophication. Permeable reactive barriers (PRBs) that intercept contaminated groundwater and provide a carbon source for microbially mediated denitrification are increasingly considered to remove nitrate before it reaches coastal surface waters. While woodchips have been shown to efficiently remove nitrate, open questions remain regarding the nitrogen removal performance of PRBs with different woodchip arrangements (trench-type vs column arrays), woodchip types (hardwoods vs softwoods) and the potential formation, release and fate of secondary byproducts, specifically greenhouse gases and dissolved iron. This dissertation aimed to address these knowledge gaps through a combination …
Lack Of Sleep Linked To Negative Body Image In Teens, Clara Turnage
Lack Of Sleep Linked To Negative Body Image In Teens, Clara Turnage
University of Mississippi News
OXFORD, Miss. – Poor sleep quality is often tied to mental health conditions such as anxiety and depression, but new research from the University of Mississippi suggests it may also be related to how teens feel about their appearance.
Utilization Of Flow Cytometry, Metabolomic Analyses And A Feline Infectious Peritonitis Case Study To Evaluate The Physiological Impact Of Polyprenyl Immunostimulant, Irene Lee, Amar Desai, Akshay Patil, Yan Xu, Kelley Pozza-Adams, Anthony J. Berdis
Utilization Of Flow Cytometry, Metabolomic Analyses And A Feline Infectious Peritonitis Case Study To Evaluate The Physiological Impact Of Polyprenyl Immunostimulant, Irene Lee, Amar Desai, Akshay Patil, Yan Xu, Kelley Pozza-Adams, Anthony J. Berdis
Chemistry Faculty Publications
Measles, hepatitis C, and COVID-19 are significant human diseases caused by RNA viruses. While vaccines exist to prevent infections, there are a small number of currently available therapeutic agents that can effectively treat these diseases after infection occurs. This study explores a new therapeutic strategy using a small molecule designated polyprenyl immunostimulant (PI) to increase innate immune responses and combat viral infections. Using a multi-disciplinary approach, this study quantifies the effects of PI in mice and THP-1 cells using flow cytometry to identify immune phenotypic markers and mass spectroscopy to monitor the metabolomic profiles of immune cells perturbed by PI …
Multi-Level Collaborative Governance Framework For Designing Accountable Ai Systems For Emergency Management, Yu-Che Chen, Chun-Hua Tsai, Edouardo Zendejas
Multi-Level Collaborative Governance Framework For Designing Accountable Ai Systems For Emergency Management, Yu-Che Chen, Chun-Hua Tsai, Edouardo Zendejas
Information Systems and Quantitative Analysis Faculty Publications
This paper addresses a gap in the AI governance literature in understanding collaboration between national governments and tribal nations in governing AI systems for emergency management. This conceptual work develops and presents a governance design framework for accountable AI systems to fill the knowledge gap by drawing from the fields of public administration, information systems, indigenous studies, and emergency management. This framework situates the governance framework in a cross-sovereignty historical, legal, and policy contexts. It captures the multi-level features and embeddedness of governance structures, including the levels of collaborative governance structure, software system governance rules, and technical software system design. …
Comparing Performance Of Aquaponics Systems Using Different Designs And Fish Feeds, Cody G. Willmore
Comparing Performance Of Aquaponics Systems Using Different Designs And Fish Feeds, Cody G. Willmore
Biology Theses, Dissertations, and Student Creative Activity
Future food production requires sustainable approaches that used both land and water resources efficiently, while remaining economically viable. One approach is aquaponics, the practice which combines hydroponics and aquaculture, as a sustainable food producing system. Aquaponic systems are unique, as the system can be designed to reuse and repurpose locally sourced materials and resources to meet individual needs. However, productivity of these systems can be inefficient or inconsistent, impacting the viability of aquaponics. The first objective of my study was to compare how system design between a do-it yourself reclaimed-materials aquaponic system and a prefabricated aquaponic setup affects water quality …
An End-To-End Concatenated Cnn Attention Model For The Classification Of Lung Cancer With Xai Techniques, Fariha Haque, Mohammad Asif Hasan, Md. Abu Ismali Siddique, Tonmoy Roy, Tonmoy Kanti Shaha, Yamina Islam, Avijit Paul, Muhammad E. H. Chowdhury
An End-To-End Concatenated Cnn Attention Model For The Classification Of Lung Cancer With Xai Techniques, Fariha Haque, Mohammad Asif Hasan, Md. Abu Ismali Siddique, Tonmoy Roy, Tonmoy Kanti Shaha, Yamina Islam, Avijit Paul, Muhammad E. H. Chowdhury
Instructional Technology and Learning Sciences Faculty Publications
In the field of medical imaging, deep learning (DL) techniques have made significant contributions to the detection and classification of various cancers. Identifying the precise regions in medical images containing cancerous cells plays a crucial role in the diagnostic process. Early and accurate cancer detection is essential for effective treatment and improved patient outcomes. However, manual diagnosis is labor-intensive, requiring the specialized expertise of radiologists, and the increasing number of cancer cases presents challenges in processing large volumes of image data efficiently. To address these challenges, an end-to-end concatenated Convolutional Neural Network (CNN) attention model has been proposed for automatic …
Identification Of Surrogate Biomarkers For Mucopolysaccharidosis Type Iva, Yasuhiko Ago, Shaukat Khan, Kimberly Klipner, Allison Bradford, Shunji Tomatsu
Identification Of Surrogate Biomarkers For Mucopolysaccharidosis Type Iva, Yasuhiko Ago, Shaukat Khan, Kimberly Klipner, Allison Bradford, Shunji Tomatsu
Department of Pediatrics Faculty Papers
Mucopolysaccharidosis type IVA (MPS IVA, Morquio A syndrome) is a rare inherited disorder characterized by skeletal dysplasia due to deficient N-acetylgalactosamine-6-sulfate sulfatase activity, resulting in glycosaminoglycan (GAG) accumulation. Identifying accurate biomarkers reflecting clinical severity and therapeutic response remains challenging. This study evaluated potential surrogate biomarkers, including N-terminal pro-C-type natriuretic peptide (NT-proCNP), collagen types I and II, mono-sulfated keratan sulfate (KS), di-sulfated KS, and chondroitin-6-sulfate (C6S), in blood and urine samples from 60 patients ranging from 1 to 62 years of age. NT-proCNP levels were significantly elevated in patients of all ages and negatively correlated with growth impairment, especially after 8 …
A Complete Transfer Learning-Based Pipeline For Discriminating Between Select Pathogenic Yeasts From Microscopy Photographs, Ryan A. Parker, Danielle S. Hannagan, Jan H. Strydom, Christopher J. Boon, Jessica Fussell, Chelbie A. Mitchell, Katie L. Moerschel, Aura G. Valter-Franco, Christopher Cornelison
A Complete Transfer Learning-Based Pipeline For Discriminating Between Select Pathogenic Yeasts From Microscopy Photographs, Ryan A. Parker, Danielle S. Hannagan, Jan H. Strydom, Christopher J. Boon, Jessica Fussell, Chelbie A. Mitchell, Katie L. Moerschel, Aura G. Valter-Franco, Christopher Cornelison
Faculty Articles
Pathogenic yeasts are an increasing concern in healthcare, with species like Candida auris often displaying drug resistance and causing high mortality in immunocompromised patients. The need for rapid and accessible diagnostic methods for accurate yeast identification is critical, especially in resource-limited settings. This study presents a convolutional neural network (CNN)-based approach for classifying pathogenic yeast species from microscopy images. Using transfer learning, we trained the model to identify six yeast species from simple micrographs, achieving high classification accuracy (93.91% at the patch level, 99.09% at the whole image level) and low misclassification rates across species, with the best performing model. …
Re-Envisioning Nuclear Deterrence, Raul (Pete) Pedrozo
Re-Envisioning Nuclear Deterrence, Raul (Pete) Pedrozo
International Law Studies
This article examines whether the U.S. nuclear umbrella provided to allies is currently viable and whether it is time for the United States to share nuclear weapons technology with its allies in the Asia-Pacific to counter the growing nuclear threat posed by China, North Korea, and Russia. The article discusses the current capabilities and nuclear doctrine of States possessing nuclear weapons, as well as Iran’s nascent nuclear weapons program. It then discusses the current international law and regulatory regime applicable to nuclear weapons. It analyzes the threats posed by China’s and Russia’s nuclear capabilities, and how they affect U.S. nuclear …
The Association Between Neighborhood Environment, Social Relations, And The Prevalence Of Irritable Bowel Syndrome, Negin Iranfar
The Association Between Neighborhood Environment, Social Relations, And The Prevalence Of Irritable Bowel Syndrome, Negin Iranfar
Walden Dissertations and Doctoral Studies
Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction influenced by biological, psychological, and social factors. Stress and socioeconomic influences on IBS have been studied, however few studies have explored the impact of neighborhood and social environments across racial and ethnic groups and sex at birth. The biopsychosocial framework was used to examine whether built environment and social context contribute to IBS prevalence. A cross-sectional analysis of 80,874 participants from the All of Us Research Program was conducted to assess the associations between IBS and six neighborhood and social factors: safety, structure, cohesion, supportive relationships, social relationships, and perceived …
Creating A Positive Social-Emotional Learning Environment For Transgender Students: A Post-Pandemic Participatory Action Research, Mark Christopher Maranto
Creating A Positive Social-Emotional Learning Environment For Transgender Students: A Post-Pandemic Participatory Action Research, Mark Christopher Maranto
Dissertations
This qualitative research employing participatory action protocols (PAR) engages a limited number of gender minority adolescents (current transgender, nonbinary, and gender-fluid secondary students) and allied staff members at one large Midwestern public high school district. The principal purpose is to improve transgender secondary student schooling experiences. This study extends the current educational discourse on SEL (social-emotional learning) in post-pandemic high schools as far as the commitment to improving students' sense of belonging, growth mindset, resilience, and well-being should be a top priority for all educators. The primary researcher positions all participants as co-researchers to explore ways that could improve the …
A Multi-Level Gene-Diet Interaction Analysis Of Fish Oil And 14 Polyunsaturated Fatty Acid Traits Identifies The Fads And Gpr12 Loci, Han Chen
Faculty, Staff and Student Publications
Fish oil supplements (FOS) are known to alter circulating levels of polyunsaturated fatty acids (PUFAs) but in a heterogeneous manner across individuals. These varied responses may result from unidentified gene-FOS interactions. To identify genetic factors that interact with FOS to alter the circulating levels of PUFAs, we performed a multi-level genome-wide interaction study (GWIS) of FOS on 14 plasma measurements in 200,060 unrelated European-ancestry individuals from the UK Biobank. From our single-variant tests, we identified genome-wide significant interacting SNPs (p < 5 × 10-8) in the FADS1-FADS2 gene cluster for total omega-3, omega-3%, docosapentaenoic acid (DHA), DHA%, and the omega-6 to omega-3 ratio. Among the interaction signals for omega-3%, the lead SNP, rs35473591 (C>CT, CT allele frequency = 0.34), had a lower association effect size in the FOS-taking group (β = 0.35 for …
Strengthening Occupational Health And Safety (Ohs) In Schools To Minimize Risks For Students, Teachers, And Visitors: Policy Recommendation, Wiwik Eko Pertiwi, Hanifa Maher Denny, Yuliani Setyaningsih, Agung Dwi Laksono
Strengthening Occupational Health And Safety (Ohs) In Schools To Minimize Risks For Students, Teachers, And Visitors: Policy Recommendation, Wiwik Eko Pertiwi, Hanifa Maher Denny, Yuliani Setyaningsih, Agung Dwi Laksono
Journal of Indonesian Health Policy and Administration
Vocational schools equip students with practical skills and expose them to industry-related hazards, making Occupational Health and Safety (OHS) a crucial aspect of the school environment. This study aims to identify key factors behind the weak implementation of OHS in vocational schools. A literature review used articles published between 2017–2024 from national and international journals. The review found poor OHS implementation stems from lack of awareness, inadequate policies, insufficient infrastructure, weak safety culture, and negligence in accident prevention. To address these issues, the study recommends OHS education and training, improvement of school infrastructure, curriculum integration, formation of safety teams, and …
In Vivo Crispr Activation Screen Identifies Acyl-Coa-Binding Protein As A Driver Of Bone Metastasis, Hongqi Teng, Qinglei Hang, Caishang Zheng, Yuelong Yan, Shaomin Liu, Yang Zhao, Yalan Deng, Litong Nie, Weiche Wu, Marisela Sheldon, Zachary Yu, Wei Shi, Jianxuan Gao, Chenling Meng, Consuelo Martinez, Jie Zhang, Fan Yao, Yutong Sun, Di Zhao, Boyi Gan, Tong Meng, Li Ma
In Vivo Crispr Activation Screen Identifies Acyl-Coa-Binding Protein As A Driver Of Bone Metastasis, Hongqi Teng, Qinglei Hang, Caishang Zheng, Yuelong Yan, Shaomin Liu, Yang Zhao, Yalan Deng, Litong Nie, Weiche Wu, Marisela Sheldon, Zachary Yu, Wei Shi, Jianxuan Gao, Chenling Meng, Consuelo Martinez, Jie Zhang, Fan Yao, Yutong Sun, Di Zhao, Boyi Gan, Tong Meng, Li Ma
Faculty, Staff and Student Publications
One of the most common sites of cancer metastasis is to the bone. Bone metastasis is associated with substantial morbidity and mortality, and current therapeutic interventions remain largely palliative. Metastasizing tumor cells need to reprogram their metabolic states to adapt to the nutrient environment of distant organs; however, the role and translational relevance of lipid metabolism in bone metastasis remain unclear. Here, we used an in vivo CRISPR activation screening system coupled with positive selection to identify acyl-coenzyme A (CoA) binding protein (ACBP) as a bone metastasis driver. In nonmetastatic and weakly metastatic cancer cells, overexpression of wild-type ACBP, but …
Genome-Wide Association Study For Ashy Stem Blight Resistance In Usda Common Bean Germplasm, Ainong Shi, Deigo M. Viteri, Angela M. Linares-Ramirez, Haizheng Xiong, Senyu Chen
Genome-Wide Association Study For Ashy Stem Blight Resistance In Usda Common Bean Germplasm, Ainong Shi, Deigo M. Viteri, Angela M. Linares-Ramirez, Haizheng Xiong, Senyu Chen
Horticulture Faculty Publications and Presentations
Ashy stem blight (ASB), caused by the fungus Macrophomina phaseolina (Tassi) Goidanich, poses a significant threat to common bean (Phaseolus vulgaris L.) cultivation worldwide. Due to the limited effectiveness of fungicides against ASB, the development of genetically resistant cultivars offers an eco-friendly and sustainable management strategy. This study aimed to accelerate genetic improvement in common bean by integrating molecular breeding tools with conventional breeding approaches to enhance ASB resistance. A total of 335 common bean germplasm accessions from the United States Department of Agriculture (USDA) Germplasm Resources Information Network (GRIN) collection were evaluated for their response to the PRI21 M. …
Protein Stability Retention Under Harsh Conditions, Kaylen Su
Protein Stability Retention Under Harsh Conditions, Kaylen Su
Student Theses and Dissertations
Plastic waste is a growing environmental concern due to its resistance to natural degradation, leading to long-term accumulation in landfills and oceans. One potential solution is enzymatic degradation, where specific enzymes break down plastic into smaller, biodegradable components. However, enzymes often lose their effectiveness under the extreme conditions plastics experience during manufacturing, such as high temperatures, mechanical stress, and dehydration. This study explores whether small molecules, known as ligands, can help stabilize enzymes and improve their ability to break down plastics.
Using molecular dynamics simulations, we tested four ligands—poly(ethylene glycol) (PEG), 6-hydroxyhexanoic acid (HHA), benzalkonium chloride (BC), and 6-aminohexanoic acid …