Digital Commons Network^™

Global Access Needs Innovations For Producing Affordable Monoclonal Antibodies And Cell Culture-Based Vaccines With Easy To Use Delivery Technologies, Vijay Yabannavar

Cell Culture Engineering XIX

Please click Additional Files below to see the full abstract

Unlocking Productivity In An Upstream Continuous Process By Combining Media Concentrates And Multi-Phase Feeding, Nuno Carinhas, Mengyao Li, David Garcia, Diana Lupea, Adriano Del Priore, Werner Nelson, Sylvius Willerich

Cell Culture Engineering XIX

Please click Additional Files below to see the full abstract

Ai-Assisted Model-Guided Image Reconstruction Methods For Photoacoustic And Ultrasound Computed Tomography, Luke Joseph Lozenski

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoacoustic computed tomography (PACT) and ultrasound computed tomography (USCT) are two emerging medical modalities that hold great promise for both pre-clinical and clinical imaging applications, including cancer diagnosis and management. PACT is a hybrid imaging modality that combines benefits from both optical and acoustic imaging to provide high contrast images of biological absorbers. USCT is an ultrasound imaging modality that provides high-resolution quantitative images of acoustic properties utilizing accurate physics models. Both PACT and USCT can be applied for monitoring or diagnosis of cancer and are non-invasive and radiation free. However, both imaging modalities are in the early stages of …

Beyond The Label: Unveiling Greenwashing Impacts On Consumer Purchasing In Sunscreen Packaging, Kailee Ransom

Honors Projects

The purpose of this research project is to unveil how the use of greenwashing tactics in marketing can influence a consumer’s actions and purchasing behavior in regard to sunscreen product packaging. It aims to uncover whether environmentally charged language or imagery (or both) on a product has an impact on a consumer’s willingness to purchase the product and their perceptions of the product’s health for their body and the environment. Additionally, are certain demographic profiles - considering a consumer’s age, income level or education level - more inclined to have a positive perception of “environmentally-friendly” sunscreen products?

To answer these …

Intouch Week Of April 28, 2025, New York Medical College

InTouch

• School of Medicine Class of 2027 Takes Pivotal Step from Classroom to Clinic
• NYMC Takes Hard Hat Tour of Ellis Island
• NYMC Hosts 11th Annual Drs. Gabor and Harriette Kaley Endowed Lecture
• Students Celebrate Earth Day
• Holocaust Survivor and Former Sunshine Cottage TB Resident Visits NYMC
• NYMC Chapter of Building Next Generation of Academic Physicians Recognized with Chapter of the Year Award
• Student Spotlight: Rewan and Sewar Alrabadi Aspire to Make Double the Impact in Physical Therapy

Bedtime Or Game Time: The Impact Of Chronotype Matching On Spectators Moods, Callie Hart

Honors College Theses

Chronotypes have been shown to affect various aspects of life including health and day to day activities such as eating and exercising (Pacheco & Rehman, 2022). Research also indicates that chronotypes can have a direct impact on a person’s mood (Kim et al., 2021). The purpose of the current study was to examine the relationship between peoples’ chronotype and their mood at a sporting event. It was hypothesized that participants who attend the game at their preferred chronotype time will report being in a better mood and have higher levels of energy than if they attend a game that starts …

From Clusters To Frameworks: Synthesis, Engineering, And Application Of Sub-2-Nanometer Nanoclusters And Microporous Covalent Organic Frameworks, Melika E Kenari

Chemistry Theses and Dissertations

In this dissertation, we have investigated the complex interplay of atomic composition, structural modifications in covalent organic frameworks (COFs), and atomic-level designs in bimetallic chiral nanoclusters (NCs). By synthesizing COFs and bimetallic NCs, we elucidated how these elements govern their exceptional catalytic, optical, and electronic properties. Our work demonstrates that precise atomic adjustments, tailored pore engineering in COFs, and the strategic use of chiral ligands in NCs enable fine-tuned reactivity and stability. These advancements were applied to enhance photocatalytic performance, optimize iodine adsorption, and facilitate asymmetric A3 coupling reactions, laying a robust foundation for practical applications and future innovations in …

Quantifying And Characterizing Microplastics In The Greater Philadelphia Region, Emily Lybashev

Biology Honors Papers

Plastic is one of the world's most useful and versatile materials, so it is no wonder that 400 million tons are produced yearly. When exposed to weathering, heat, water, and organisms, plastic degrades and produces microplastics. These microplastics have managed to leach into our oceans, local waterways, bodies, and even our atmosphere. The negative implications of microplastic contamination in our environment are slowly being uncovered with concerns of toxin buildup. Additionally, the amount of microplastics we are exposed to through local waterways is rarely quantified. Though microplastic research is picking up pace, the Schuylkill River which spans the Greater Philadelphia …

Task Demands Influence Search Strategy Selection In Otoconia-Deficient Mice, Ryan M. Yoder, Lucas C. Carstensen, Keshav Jagannathan

Psychology

Introduction: The vestibular system plays a crucial role in visual and non-visual navigation. Our recent study found that signals from the otolith organs are necessary for mice’s use of distal visual cues to guide navigation to an invisible goal. Somewhat surprisingly, however, performance was not significantly impaired on some spatial tasks (e.g., Barnes maze reference memory task), questioning the role of otolith signals in visual navigation.

Methods: We report the results of several additional tests of reference memory performance and search strategy use on two versions of the Barnes maze, in an attempt to establish further understanding of the otolithic …

The Role And Expression Of Pros-1 In The C. Elegans Gonad, Brandon W. Thomas, Mary B. Kroetz, Roberta Challener

Undergraduate Theses

The nematode, formally known as Caenorhabditis elegans, has served as an excellent model organism in understanding fundamental biological processes, including those governed by conserved genes like pros-1. pros-1 is partially responsible for the formation of tubular structures within the organism. Glial cells and excretory canals are both examples of tubular structures governed by pros-1. pros-1 orchestrates the embryonic development of these cell types by modulating cell proliferation and differentiation, thus ensuring proper morphogenesis and organogenesis. Its regulatory influence likely extends beyond embryogenesis, potentially affecting reproductive processes as well. Furthermore, the evolutionary conservation of pros-1 underscores its significance …

Quality Improvement Project Empowering Outpatient Providers: A Training Initiative On Social Determinants Of Health, Shannon Wrenn

Doctor of Nursing Practice Projects

Healthcare providers play a critical role in assessing social determinants of health (SDOH), yet many lack the knowledge and confidence to effectively address these factors during patient encounters. Research indicates that SDOH contribute to approximately 80% of health outcomes, yet only 41% of providers feel confident in discussing them with patients. This quality improvement project aimed to improve provider knowledge and confidence about SDOH as measured by pre- and post-education assessments. The SDOH targeted training took place at an outpatient interventional nephrology practice in Memphis, Tennessee. A quasi-experimental, one-group pretest-posttest design was used. Ten clinical staff members participated in an …

Integrating Human-Centered Design Into Undergraduate Stem Capstone Courses: A Food Product Development Case Study, Saadeddine Shehab, Dawn Bohn, Lucas O'Bryan, Luettamae Lawrence, Mike Tissenbaum

Instructional Technology and Learning Sciences Faculty Publications

This study examines the integration of human-centered design (HCD) in a Food Science capstone course and explores its impact on students’ learning outcomes and skill development. This case study investigated how 42 undergraduate students engaged with HCD processes—including understanding, synthesizing, ideating, prototyping, and implementing—to develop innovative food products. Through pre- and post-surveys, interaction analysis, and performance assessments, the findings revealed that HCD activities significantly enhanced students’ knowledge, collaboration, creativity, and metacognitive skills. Additionally, students demonstrated improved food science competencies, such as product formulation and sensory evaluation. This study highlights the benefits of embedding HCD within STEM curricula to foster authentic, …

Protective And Risk-Related Factors Associated With College Student Burnout, Dominic X. Chavez

Honors Theses

Burnout is an occupational phenomenon commonly defined by the exhaustion, cynicism, and lack of efficacy a person experiences with regard to their role (i.e., educator, healthcare worker, student, etc.). Despite the prevalence of burnout in academia, very few research studies have attempted to examine the variables associated with burnout’s severity in the case of American college and university students. Thus, the current study sought to analyze the protective and risk-related factors previously determined to be associated with academic burnout within a college population. Specifically, burnout self-ratings were compared to perceived burnout stigma, resilience, perceived social support, help-seeking attitudes, and perceived …

Ultrasonography As A Method For Identifying Biological Sex In Captive Hellbenders (Cryptobranchus Alleganiensis), Logan N. Collom

Honors Theses

The hellbender (Cryptobranchus alleganiensis) is the United States’ largest aquatic salamander and is mainly found across the eastern U.S. There are two subspecies of hellbenders, one of which is listed as endangered by the US Fish and Wildlife Service and the other considered a species of conservation concern and a candidate for listing under the Endangered Species Act. There have been several captive breeding programs established at zoos and universities across the U.S., which require a dependable method for sexing their individuals. Ultrasound imaging has previously been used to identify the sex of other amphibian species and track …

Quantifying The Rates Of Coastal Change Along Smith Island, Maryland, Sarah Lacy, Ravi Sankar

Longwood Senior Thesis Proposal

As increased climate variability continues to alter the environment, coastal landscapes are becoming increasingly vulnerable to geomorphic change. Coastal erosion, driven by rising sea levels, land subsidence, more intense storm events and human-induced activities poses a serious threat to the sustainability and resilience of island environments like Smith Island, a small marsh island located in the Chesapeake Bay. This study investigates the impacts of recent shoreline change along selected alongshore segments of the island’s coast. Using a combination of aerial imagery, field surveying techniques, and novel geospatial analyses, the project aims to identify areas at highest risk of erosion and …

Heavy Metals In Spices From Lancaster, Pa: Arsenic, Cadmium, And Lead Exposure Risks And The Need For Regulation, Andrew Huff, Hoi Lam, Anuj Ghimirey, Jay Goldring, Michelle Pimentel, Harriet Okatch

College of Population Health Faculty Papers

Heavy metal exposure is associated with adverse health effects in children including impaired cognitive functioning. Studies have identified spices as a potential source of heavy metals. However, in Lancaster, PA no such studies have been conducted. Hence the aim of this study was to quantify arsenic (As), cadmium (Cd) and lead (Pb) in spices from Lancaster, PA. Spices were either purchased from stores in Lancaster or obtained as donations from families in Lancaster. As, Cd, and Pb were quantified using inductively coupled plasma-mass spectrometry. The Wilcoxon rank sum test was used to compare the median heavy metal concentrations in store-purchased …

Cliona Delitrix Population Demographics And Ecological Succession On San Andrés Reefs, Colombia, Maya Clarke

Harriet L Wilkes Honors College Theses

As climate change decimates coral populations, excavating sponges are becoming prominent in some reefs as critical bioeroders. This thesis aims to assess ecological succession patterns and population demographics of the excavating sponge Cliona delitrix on San Andrés, Colombia reefs over 20 years. Population growth was quantified. Growth was constant, with recruits replacing dead mature sponges at an equal rate. A frequency analysis was run to assess the successor prevalence per substratum. On live corals, succession after C. delitrix death is dominated by a diverse community of organisms, including macroalgae, turf algae, sponges, calcareous algae, and others. Understanding reefs as dynamic …

Her Bun + My Oven = Our Child: Protecting The Legal Parentage Of Lgbtq+ Mothers And Their Children Conceived Via Reciprocal In Vitro Fertilization In Ohio, Courtney Hutchinson

Cleveland State Law Review

This Note discusses legal parentage in Ohio for two-women couples who expand their families via reciprocal in vitro fertilization or egg-sharing, where one woman is the genetic parent and the other is the gestational parent. Currently, the gestational mother is guaranteed legal parentage at the time of the child’s birth, while the genetic mother must petition the court for a formal adoption to protect her legal rights. A thorough review of court precedent regarding same-sex marriage makes clear that the public policy of Ohio permits two women to share in the legal rights of parentage. Furthermore, Ohio courts have regularly …

The Chemistry Of Decomposition: The Mechanisms To Decay The Human Body, Lydia J. Buxa

Senior Honors Theses

Taphonomic analysis separates decomposition into four major stages: fresh, early decomposition, advanced decomposition, and skeletonization. It is easy to demarcate the observable changes to the body, but it is far more difficult to know what underlying biochemical processes are occurring. Fresh decomposition begins with algor mortis, livor mortis, and rigor mortis, which sets the stage for the major workforces of decomposition: autolysis and putrefaction. The external signs of decomposition appear in early decomposition, which can be attributed to the breakdown of proteins, lipids, carbohydrates, and nucleic acids. This also leads to major changes in the moisture levels during advanced decomposition, …

Focus, 2025, Winter, Andrews University

Focus

FOCUS (ISSN 1077-9345) is published quarterly, free of charge, for alumni and friends of Andrews University, an institution owned and operated by the Seventh-day Adventist Church.

Determining The Bioaccumulation Of Minor Cannabinoids In Zebrafish Larvae, Kamdyn A. Holt

Honors Theses

Due to the increasing prevalence of cannabis product availability and usage in the modern United States, particularly among pregnant individuals, evaluating the bioaccumulation of minor cannabinoids to further understand the adverse effects of cannabinoids during early development is critical. This study quantitated the uptake of eight minor cannabinoids ((∆8-tetrahydrocannabinol (∆8-THC), ∆9-THC, ∆10-THC, cannabidiol (CBD), cannabigerol (CBG), cannabinol (CBN), tetrahydrocannabivarin (THCV), and hexahydrocannabinol (HHC)) in zebrafish larvae following water-borne 2 µM exposures from 6 to 96 hours post fertilization (hpf). Larvae were homogenized at 96 hpf and analyzed using a gas chromatography- mass spectrometry (GC-MS) method developed in this study. Bioconcentration …

Effect Of Asphalt Content On Low-Field Nuclear Magnetic Resonance Spectrum And Aging Evaluation Of Asphalt Mixtures, Chenyue Mei, Wei Wang, Junan Shen, Jinkun Sun, Yilin Xu, Jia Che

Civil Engineering & Construction: Faculty Publications

The aging of asphalt mixtures has a significant impact on the service life of asphalt pavements. Currently, the commonly employed method for assessing aging involves the extraction of asphalt from asphalt mixtures using the Abson method. However, this method is known to be detrimental to the extracted asphalt samples, time-consuming, and environmentally unfriendly. This study explored a novel non-destructive method for assessing asphalt aging, known as low-field nuclear magnetic resonance (LF-NMR). It primarily investigated the influence of asphalt content in asphalt mixtures on the patterns of LF-NMR spectra. Specifically, it examined the effect of asphalt content on LF-NMR spectra in …

Study Group Environments And Their Connection To Study Plans And Strategies, Tatyanna Caputo

Harriet L Wilkes Honors College Theses

Students have a mental image of how they intend to study but may fail to anticipate possible distractions or unexpected obstacles. A potential solution is for students to collaborate in study groups. If students fear disappointing their fellow peers, they may be more likely to fulfill their intended plans. In addition, studying in groups may encourage the use of active study strategies. In this study, college students reported their upcoming study plans, which were then analyzed to see if students planned to work with others and use stronger study strategies. We correlated their plans with the students’ later self-reports on …

Prediction Of Diabetes Using Machine Learning, Walid Abdulla Abdulrahim

Theses

This research seeks to compare the overall health of diabetic patients with that of their healthy counterparts based on various heath indicators obtained from a large dataset comprising of pregnancies, glucose levels, blood pressure, skin thickness, insulin, BMI, diabetes pedigree function and age. Relative to the healthy group, increased average glucose level, higher BMI, and older age are identified in the diabetic participants. Most importantly, the results show that obesity is a significant risk factor for diabetes, and many diabetics have BMIs that are elevated above healthy levels. The data also points towards the fact that insulin resistance and prevalence …

How Biophilic Design Impacts Office Spaces, Addison Carter

Honors Projects

Many working individuals experience burnout and dissatisfaction in their jobs. Although is this a result of individual mental strain, or are there other environmental factors contributing to the problem? This study investigates the impact of design on well-being and examines how biophilic design can serve as a solution to the negative effects certain architectural features may have on occupants. A literature review was conducted; it analyzed existing research on topics such as office design, biophilic design, and the influence of architecture on comfort and wellness. To explore how biophilic design can be applied in all settings, not just new construction, …

Chimes: April 28, 2025, Calvin University

Chimes

New native meadow breaks ground on Earth Day by Ian Tjoelker

Film students prepare for media showcase by Stella Stachowiak

Students premier original compositions at New Music at Calvin Concert by Graham Kort

Calvin responds to a national wave of visa revocations by Grace Buller

A dive into the world of the The Weather Belt by Ethan Meyers

Women's lacrosse falls to Hope in regular season finale, looks ahead to MIAA tournament by Zach Kern

Students unsure of effects of Calvin's Synod report by Clare Rybicki, McKenna Wilkinson & Sarah Sparling

Top of the Class: Beast Games meets Survivor at …

Electrocatalytic Nitric Oxide Reduction To Yield Ammonia Over Fe3C Nanocrystals, Sen Lin, Lang Zhang, Tong Hou, Jun-Yang Ding, Zi-Mo Peng, Yi-Fan Liu, Xi-Jun Liu

Journal of Electrochemistry

Nitric oxide (NO), which generally originates from vehicle exhaust and industrial flue gases, is one of the most serious air pollutants. In this case, the electrochemical NO reduction reaction (NORR) not only removes the atmospheric pollutant NO but also produces valuable NH₃. Hence, through the synthesis and modification of Fe₃C nanocrystal catalysts, the as-obtained optimal sample of Fe₃C/C-900 was adopted as NORR catalyst at ambient conditions. As a result, the Fe₃C/C-900 catalyst showed an NH₃ Faraday efficiency of 76.5% and an NH₃ yield rate of 177.5 μmol·h^–1·cm^{–2 …}

Digital Discourse On Alzheimer’S Disease: A Text Analysis Of Crosscultural Sentiments In Online Communities, Maryam Imran

Harriet L Wilkes Honors College Theses

Alzheimer’s disease is a neurological condition characterized by a significant decline in cognitive function. Due to its severe effects and the absence of a cure, early diagnosis and treatment are crucial for slowing its progression. My project examines how cultural perceptions of Alzheimer’s disease are reflected in digital discourse. Using Voyant, a text analysis tool, and the NRC Emotion Lexicon, I analyzed Reddit discussions from South Asian, East Asian, and North American individuals, categorizing their posts into three themes: diagnosis perceptions, treatment decisions, and family/social dynamics and classifying sentiments as negative, positive, or neutral to gain a deeper understanding of …

How Effective Are Machine Learning Algorithms In Enhancing Marketing Strategies?, Kassidy Dunn

Harriet L Wilkes Honors College Theses

In recent years, machine learning algorithms have become a vital tool in marketing, yet their impact remains underexplored. This study investigates the mechanisms and applications of machine learning algorithms in marketing strategies, assessing whether they benefit or restrict the effectiveness of marketing strategies. Through relevant research and case studies, we argue that while machine learning-driven marketing offers measurable benefits in personalization and return on investment, its implementation must be balanced with ethical considerations to avoid biased outcomes.

Humans Are Animals: A Review Of Animals Are People, Matthew R. Jamnik

The International Journal of Ecopsychology (IJE)

The Animals are People (AAP) story reflects a philosophical inquiry into the nature of sentience, what it means to cultivate community, and the ethical and moral considerations behind “sanctuary.”It gifts a heartwarming journey about growing up, rooting down, and falling in love with life. “We save the animals, then the animals save us,” and so the story goes.