Digital Commons Network^™

Begin Again: Blooming, Samantha Hope Boulgarides

University Honors Theses

Begin Again: blooming is a poetry thesis that explores the complexities of trauma, recovery, and identity through a feminist lens. Drawing from the lyric tradition, each poem serves as an emotional excavation, using voice, fragmentation, and address to create intimacy while resisting linear narrative and traditional poetic conventions.

The collection examines how pain imprints itself on the body and memory, with pieces like "Dear Dad," "Clean," and "My Baby" demonstrating the tension between tenderness and pain. Visually experimental and emotionally charged, these poems refuse erasure, reclaiming agency through raw articulation and form. Rather than seeking resolution, the speaker circles truth, …

The Impact Of Nicu Death On Bereaved Mothers, Jennie Terranova

University Honors Theses

Infant loss in the United States occurs 5.6 per 1,000 live births. This paper examines risk factors that contribute to neonatal death. Prematurity is a risk factor for NICU admission. A portion of premature babies receiving care in the NICU will die. The stressful nature of the NICU has been studied widely in journals. The impact of NICU death on hospital staff and bereaved parents has been studied less. Mortality studies suggest that bereaved mothers are at a high risk of dying within the first 5 years after their child has died. Despite the frequency of maternal death post-child loss, …

More Than Hormones: Psychological Consequences Of The Medicalized Menopausal Experience, Haley Derrickson

University Honors Theses

Menopause, a transitional period that roughly half the population may experience, has a high degree of variability in onset and intensity of symptoms, one of which is depression. It is also a period in which the lives of those transitioning are highly medicalized. This literature review investigates how medicalization has increased since the term was created, and how it impacts perimenopause, menopause, and mental health.

American Consumer Culture And Social Media Polarization: Analyzing Twentieth Century Trends And Their Effects On Twenty First Century Politics, Max Lally

University Honors Theses

The emergence of social media as a mainstream communication technology during the early twenty first century has had an outsized impact on the United States' political system. By analyzing trends in American culture and economics beginning in the decades following the end of World War Two, the circumstances that shaped social media during its development can be tied to long term historical changes. Shifts away from traditional models of community and towards rising individualism reshaped communication with both political allies and opponents. Generational shifts in political attitudes have heightened these divisions as well, as younger and liberal perspectives challenge traditional, …

Kinetic Analysis Reveals T6a-Protein Specificity For T6a And Hn6a Trna Modifications, Cassandra Mae Harker

University Honors Theses

Transfer RNA (tRNA) is essential for accurate translation of genetic information and plays a role in cellular processes such as lipid aminoacylation and bacterial conjugation. Base modifications help tRNA fold correctly and function properly. An important base modification, N6-threonylcarbamoyladenosine (t6A) occurs at position A37 in the anticodon-stem-loop of tRNA. This modification is crucial for decoding ANN codons. Interestingly, an Archeal organism, Methanocaldococcus jannaschii, can have either t6A and hydroxynorvalylcarbamoyl-6- adenosine (hn6A) modification at the same position on tRNAs. As Tsa proteins catalyze the formation of both t6A and hn6A modifications, this raises the question of whether discrimination between these …

Gianjara's Ribs: The Ecosystem, Body, Animalia, And Politic, Linus Gomez Ellis

University Honors Theses

This work is a series of four six foot tall full-body portraits of people, which are displayed alongside an actual, physical item or garment present in the associated painting. The purpose of this is to blur the line between the fiction of the individuals depicted and the viewer. By creating "portals" through which to view them as equals in stature, Linus Gomez Ellis is taking something that can be seen in the ecosystem of this fiction and making it into an objective reality. The most enduring, well preserved, and eternal pieces of history and anthropology are tall tales. This ecosystem, …

Green Weave: A Textile Guide To The Future Of Fashion, Simon Braunschweig

University Honors Theses

Fashion and technology are inextricably linked. The more advanced our technology becomes, so too does fashion and our understanding of it. Fashion is also one of the top contributors to climate change. However, modern technology has the potential to change the way fashion impacts our planet, working harmoniously with nature instead of against it. This thesis investigates the connection between technology and fashion, resulting in a handbook for fashion designers who want to implement more sustainable practices into their work with the help of modern technology.

Examining Long-Term Care For Ncaa Student-Athletes: Improving Concussion Protocols And Healthcare, Sydney Watson

University Honors Theses

Sports-related concussions (SRC) are a significant issue in collegiate athletics, particularly in high-impact sports. While the National Collegiate Athletic Association (NCAA) has protocols for immediate injury management, they don't fully address the long-term effects retired athletes experience. This paper examines whether former NCAA athletes who suffered from SRC should receive more comprehensive concussion-related healthcare. Findings reveal that current NCAA measures, such as baseline assessments and return-to-play protocols, fall short in addressing the lasting physical, cognitive, and emotional challenges of student-athletes who suffered multiple SRC. Protocols and procedures set by professional leagues like the NFL and NHL highlight the NCAA's gaps …

Exploring Vaccine Efficacy And Safety For Ms Patients On Immunosuppressant Treatment In Light Of The Covid-19 Pandemic, Rain Pross

University Honors Theses

Multiple sclerosis (MS) is a chronic neurodegenerative autoimmune disorder affecting approximately 2.8 million people worldwide. Despite decades of research to understand the molecular mechanisms of MS pathology, little is known about why the neurodegeneration caused by this illness occurs. For this reason, current treatments for MS target two broader aspects of the disease: relapse management and prevention via disease-modifying therapies. These treatments often involve immunosuppressive mechanisms, creating vulnerability to infectious diseases that became particularly concerning during the COVID-19 pandemic. This literature review examines the safety and efficacy of vaccination for MS patients on immunosuppressant therapies, highlighting the novel mRNA vaccines …

Surveying Management Strategies For Pediatric Autoimmune Hepatitis, Lillie Baca

University Honors Theses

Pediatric autoimmune hepatitis (PAIH) is a long-term condition that requires ongoing treatment and regular monitoring. It is characterized by its elevation of liver enzymes, interface hepatitis, and the specific presence of circulating autoantibodies. There is a general lack of consensus on appropriate measures of diagnostic criteria, treatment medication, and beneficial practices for monitoring the disease. The existing literature contains several subtle discrepancies that challenge a practitioner's judgement for care management of children with autoimmune hepatitis. This study is a retrospective chart review aimed at understanding the current diagnostics, treatment, and long-term management strategies of PAIH at a single center. Also, …

Controlling Corsets: Commerce, Dress Reform, Medicine, And Misogyny In Nineteenth-Century Women's Dress, Emily Klesch

University Honors Theses

In the nineteenth century, women's dress depended on the usage of the corset. Without it, a woman's outfit was uncomfortable to wear and largely impractical. Because of how necessary the garment was to women's clothing, it became the focus of criticism from many different angels, including but not limited to the medical field, dress reform, and businesses which manufactured and sold corsets to consumers. These criticisms, although directed at the corset, were often thinly veiled insults to the female sex, and reflected larger societal fears about women's places in society as women's liberation movements began to gain more traction. It …

Messy Kitchens, Clean Hands, Emily Camp

University Honors Theses

Contemporary industrial food systems are well-tuned towards their primary goal: the efficient production of cheap food to generate high profits. Perhaps nowhere is this more acute than in the production of industrial meat. Here, workers, consumers and animals are trapped in a system that ignores their interests in order to achieve maximum profit for shareholders. But how does modern industrial meat production remain mostly hidden from view?

This interdisciplinary art and cultural history thesis explores this question by looking to the kitchen, and more specifically, to its decor. These decorative objects both reflect and enable a complex ideological transformation. I …

Large-Scale Plasma Proteomic Profiling Unveils Diagnostic Biomarkers And Pathways For Alzheimer’S Disease, Gyujin Heo, Ying Xu, Erming Wang, Muhammad Ali, Hamilton Se-Hwee Oh, Patricia Moran-Losada, Federica Anastasi, Armand González Escalante, Raquel Puerta, Soomin Song, Jigyasha Timsina, Menghan Liu, Daniel Western, Katherine Gong, Yike Chen, Pat Kohlfeld, Allison Flynn, Alvin G Thomas, Joseph Lowery, John C Morris, David M Holtzman, Joel S Perlmutter, Suzanne E Schindler, Natalia Vilor-Tejedor, Marc Suárez-Calvet, Pablo García-González, Marta Marquié, Maria Victoria Fernández, Mercè Boada, Amanda Cano, Agustín Ruiz, Bin Zhang, David A Bennett, Tammie Benzinger, Tony Wyss-Coray, Laura Ibanez, Yun Ju Sung, Carlos Cruchaga

Faculty, Staff and Student Publications

Proteomic studies have been instrumental in identifying brain, cerebrospinal fluid and plasma proteins associated with Alzheimer's disease (AD). Here, we comprehensively examined 6,905 aptamers corresponding to 6,106 unique proteins in plasma in more than 3,300 well-characterized individuals to identify new proteins, pathways and predictive models for AD. We identified 416 proteins (294 new) associated with clinical AD status and validated the findings in two external datasets representing more than 7,000 samples. AD-related proteins reflected blood-brain barrier disruption and other processes implicated in AD, such as lipid dysregulation or immune responses. A machine learning model was used to identify a set …

Exploring Natural Competence Of Escherichia Coli Through Biofilm Formation, Thulni Liyanaarachchi

University Honors Theses

Escherichia coli is a species not known for natural competence; however, specific growth conditions can induce the process in this bacterium due to the presence of homologous competence genes. These conditions could be met with biofilm formation through an active growth phase in the two-layer architecture. Therefore, my thesis examined whether natural competence is exhibited in E. coli during biofilm formation as determined by the genetic transfer of ampicillin and chloramphenicol-resistance genes between two separate strains. The experiments were broken into three aims to determine the morphology of the biofilm in inter-strain co-cultures and cell-DNA mixes, the effect of …

"It Had To Stop": Content Analysis Of Fox News Library Censorship Discourse, Lex Faller

University Honors Theses

Library censorship poses a threat to inclusive communities by foreclosing the possibility of finding diverse representations through media. Certain demographics are more dependent on libraries for media access than others. Censorship is therefore especially concerning for those who cannot purchase media or afford subscriptions themselves. The most vocal proponents of contemporary library censorship are ideologically conservative; therefore, conservative media ecosystems play a key role in library censorship discourse. Fox News television is the most watched television news channel by a wide margin in the U.S. and therefore has an outsized influence on U.S. adults. This research involved a qualitative content …

A Comprehensive Literature Review Of Gender Differences In Perception And Response To Stress, Zoe M. Shankland

University Honors Theses

It is well established that psychological stress, whether acute, chronic, or recurring, creates an imbalance in the body’s ability to regulate itself, leading to the potential for long-term disease. This paper looks at the possibility that women (anyone who identifies as a woman) experience more general mental stress than men (anyone who identifies as a man) due to women experiencing unique stressors under a patriarchal society. Men and women live different lives in modern society due to differing societal expectations and biological processes for women (menstruation, pregnancy, menopause). These extra feelings of stress may be tied to traditional gender roles …

Investigating A Link Between Dna Repair And Dna Replication In Escherichia Coli Using A Bacterial Two-Hybrid System, Lo Cooper

University Honors Theses

Cells rely on nucleotide excision repair (NER) to remove bulky DNA lesions, such as those caused by UV light. In Escherichia coli, NER involves the UvrABC complex, and includes two main pathways, global genomic repair and transcription-coupled repair (TCR). While TCR, which preferentially removes lesions that block RNA polymerase on the transcribed strand of active genes, is well studied, less is known about whether a similar coupling between repair proteins and replisomes blocked by damaged DNA exists. Such a process has been suggested by a high throughput interactome study, using the replisome subunit HolC as bait and the damage …

Digesting The Details: How Cooking Shapes The Microbiome And Influences Obesity, Tracy Lieu

University Honors Theses

Obesity is a growing global health concern linked to chronic diseases and changes in the gut microbiome. While diet is known to affect gut microbes, less attention has been given to how food processing methods, such as heating, fermentation, and cold processing, change food in ways that influence the gut microbiome and health. This thesis reviews research on how different cooking and preparation techniques affect the availability of nutrients for microbial fermentation and the resulting effects on microbial diversity and metabolism. The findings show that fermentation and cold processing are the most supportive of gut health. These methods help preserve …

Quantitative Analysis Using Mri Of Patients That Are High Risk For Pancreatic Cancer, Aqsa Tarik

University Honors Theses

Pancreatic ductal adenocarcinoma (PDAC) is a cancer that is detected in its later stages, causing its five-year survival rate of 2-9% (3). The majority of patients who develop PDAC unfortunately deal with a low survival rate due to the progression of the tumor in the body. Magnetic resonance imaging (MRI) can assess the structure of the tissue within organs in the body. These scans can also be used in order to detect and diagnose tumors, allowing them to be a generator of cancer biomarkers. PDAC isn’t distinguishable on conventional images, as the pancreas will appear normal, allowing the tumor progress …

Creating Possibilities: The Ethelind Pope Brown Collection: An Overview Of Who May Have Illustrated America's Oldest Naturalist Paintings, Maksym Dedenko

University Honors Theses

This thesis investigates the Ethelind Pope Brown Collection at the University of South Carolina, a rare assembly of hand-illustrated naturalist artworks depicting an assortment of flora and fauna from the eighteenth century. Despite its artistic and educational value, the creator of the collection remains unidentified. Through close textual and visual analysis, archival research, and comparative stylistic study, this project explores several potential authorship theories while providing background to the necessity of evolving science that facilitated its creation.

The Necessity Of Improved Pica Assessment Tools And Screening Practices For Harm Reduction, Deborah Arakelian

University Honors Theses

Pica disorder refers to the consumption of non-food items, and has historically been understudied. Dangerous medical complications often arise as result of this behavior, making this a critical area of continued research. This paper reviews literature on the prevalence of pica disorder, as well as its etiologies and risk factors with the intention to identify at-risk groups who would benefit from increased screening. The current assessment tool used for screenings and research is vague and insufficient, and the development of a more comprehensive tool is critical to reduce harm. This paper discusses what should be included in an improved questionnaire, …

Integrating Methods To Investigate Phytoplankton Dynamics Along Gradients Of A Major Urban River, Nicholas Sheldon

University Honors Theses

Waterways that support human society and life on Earth host superabundant microorganisms which support all ecosystems and food webs: phytoplankton. This study aimed to identify and quantify phytoplankton in the Willamette River in order to understand the dynamics between different phyla. Building on previous studies, which showed that communities of phytoplankton change with the river environment, this work determined how eukaryotic and prokaryotic phytoplankton vary with one another while inhabiting the same river conditions. The approach involved sampling the Willamette river over a weekly time series and combined analytical techniques of qPCR, flow cytometry, and image cytometry to assess population …

Access To Healthcare For Rural Transgender Adults In The United States, Devon Smith

University Honors Theses

Urban and rural healthcare differ significantly in the amount of facilities, providers and kinds of specialty care that are offered in each environment. The United States is split into urban and rural counties in any given region, and based on those population sizes, are the allocation of healthcare resources for residents. In rural areas in the U.S., transgender adults lack access to gender-affirming care and encounter a lack of gender-affirming care providers due to workforce shortages, discrimination, and a lack of cultural competency. To determine if these residents lacked access to care compared with their urban counterparts, I performed a …

Filling The Sackett Gap: The Private Governance Option, Michael P. Vandenbergh, Elodie O. Currier Stoffel, Steph Tai

Vanderbilt Law School Faculty Publications

The Supreme Court's decision in Sackett v. EPA reversed fifty years of federal Clean Water Act wetlands protections and removed federal oversight from roughly half of the wetlands in the United States. This Article proposes a viable new conceptual model and tools to close the Sackett Gap-the gap between the wetlands protected before and after Sackett. Scholars have argued for federal measures to fill the Sackett Gap, but these actions face substantial challenges. Congress is unlikely to adopt new wetlands legislation, agencies are constrained by Sackett's expansive language, the end of Chevron deference, and the 2024 presidential election, and lower …

Data Driven Analysis Of Samara Seed Kinematics And Dynamics, Shashwat Sparsh

Master's Theses

Samara Seeds are a class of fruit most famously belonging to the Acer species and are characterized by their single-bladed geometry and their auto-rotation response during descent. This steady-state auto-rotation response is the subject of aerodynamic analysis which aim to quantify the performance. The period prior to the beginning of steady-state auto-rotation is classified as the transition regime and has not been the subject of intense scrutiny.

This thesis employs a data-driven approach to analyzing the kinematic and dynamic response of these seeds during both the transition and auto-rotation stages of flight to quantify the performance with respect to the …

Spatial And Functional Metrics For Analyzing Seedling Roots, Irina Ivchenko

Master's Theses

To study the complicated structure of a maestro pea seedling root, we investigate three spatial metrics and one functional metric. The spatial metrics are fractal dimension which measures the complexity, convex hull area which measures the occupied space, and Euler characteristic which topologically describes the shape of the root. We discuss the successes of various metrics and the possible limitations they bring to analysis. As a functional metric, we study the rhizosphere: the volume radially around the root branches from which the plant accesses nutrients and water. We investigate the relationship of the rhizosphere to the root, and propose how …

Chatgpt On Chatgpt: An Exploratory Analysis Of Its Performance In The Public Sector Workplace, Jieshu Wang, Elif Kiran, S. R. Aurora, Michael Simeone, Jose Lobo

Management Faculty Publications

This study explores the impact of Generative Artificial Intelligence (GenAI), in particular, ChatGPT, on the public sector workforce in the United States, focusing on task replacement, assistance potential, and the evolving landscape of skills. Utilizing GPT-4 to evaluate 1,022 core tasks across 51 public sector occupations, we provide an exploratory analysis of the roles susceptible to ChatGPT automation and those in which ChatGPT can augment human efforts. Our findings reveal that while 63% of tasks are resistant to ChatGPT replacement, primarily due to their requirement for physical presence, emotional intelligence, and complex decision-making, tasks that are routine, rule-based, and involving …

Mae Enewsbrief Oct-Dec 2024, Department Of Mechanical And Aerospace Engineering, Michigan Technological University

Department of Mechanical and Aerospace Engineering eNewsBrief

No abstract provided.

Protecting The Future Of Medical Innovation: Balancing Fiscal Responsibility With The Need For National Institutes Of Health And Federal Health Funding, Irina Petrache, Raed A. Dweik, Michelle Ng Gong, Jesse Roman, M. Patricia Rivera, Karen J. Collishaw

Division of Pulmonary, Allergy, and Critical Care Medicine Faculty Papers

No abstract provided.

Non-Tariff Measures On Indonesian Tea Products: Do Sps And Tbt Impede Or Promote The Export?, Fikri Aldi Dwi Putro, Widyastutik Widyastutik, Nia Kurniawati Hidayat

Economics and Finance in Indonesia

Previous studies highlight the heterogeneous effects of Non-Tariff Measures (NTMs) on international trade. This study identifies the enforcement of NTMs and examines the effects on the export performance of Indonesian tea products. This study employed an inventory (coverage ratio) approach and panel regression with the Poisson-Pseudo Maximum Likelihood (PPML) method. The results indicate that 31 out of 36 analyzed destination countries enforce NTMs, with Vietnam imposing the most prevalent ones. Furthermore, SPS measures substantially promote the export of Indonesian tea products, whereas TBT measures show no significant effect. Therefore, the government needs to provide incentives and harmonize the national Voluntary …