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Role Of Progesterone Action In Inguinal Hernia Formation Via Skeletal Muscle Fibrosis And Atrophy, Tianming You, Mehrdad Zandigohar, Tanvi Potluri, Natalie Piehl, John S Coon V, Elizabeth Baker, Maya Kafali, Yang Dai, Jonah J Stulberg, David J Escobar, Richard L Lieber, Hong Zhao, Serdar E Bulun Jul 2025

Role Of Progesterone Action In Inguinal Hernia Formation Via Skeletal Muscle Fibrosis And Atrophy, Tianming You, Mehrdad Zandigohar, Tanvi Potluri, Natalie Piehl, John S Coon V, Elizabeth Baker, Maya Kafali, Yang Dai, Jonah J Stulberg, David J Escobar, Richard L Lieber, Hong Zhao, Serdar E Bulun

Faculty, Staff and Student Publications

More than 1 in 4 men will undergo surgery for inguinal hernia, which is commonly associated with fibrotic degeneration of the lower abdominal muscle (LAM) in the groin region. Utilizing a male mouse model expressing the human aromatase gene (Aromhum), previous studies showed that locally produced estradiol acting via estrogen receptor α in LAM fibroblasts leads to fibrosis, myofiber atrophy, and hernia development. Here, we found that upregulation of progesterone receptor (PGR) in a LAM fibroblast population mediates this estrogenic effect. A PGR-selective progesterone antagonist in Aromhum mice decreased LAM fibrosis and atrophy, preventing hernia formation and stopping progression of …


Conceptualizing Covid-19 As A Biosecurity Threat To The National Security Of Twelve Countries: Implications For Global Health Policy, Lydia Donkor Jul 2025

Conceptualizing Covid-19 As A Biosecurity Threat To The National Security Of Twelve Countries: Implications For Global Health Policy, Lydia Donkor

Doctoral Dissertations and Projects

Biosecurity threats, including diseases such as COVID-19, influence public health and national security policies. The COVID-19 outbreak in Wuhan, China, reveals the risks of biological agents to public health. This study investigates how varying perceptions of COVID-19 as a biosecurity threat affected public policy in 12 countries, including the United States (U.S.), the United Kingdom (U.K.), China, and Ghana, aligning with the Copenhagen School's Securitization Theory and employing causal inference methods. This research used qualitative document analysis to examine government responses to COVID-19 within a security framework among the research participants. The findings demonstrate that nations that viewed COVID-19 as …


Maintaining Elementary Student Engagement And Motivation During Stem Activities: A Phenomenology, Christopher Feiler Jul 2025

Maintaining Elementary Student Engagement And Motivation During Stem Activities: A Phenomenology, Christopher Feiler

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to describe the lived experiences of maintaining student engagement and motivation during STEM activities in elementary classrooms across the United States. For this research, I applied Bandura's self-efficacy theory as my foundational framework. The study highlights that a teacher’s perception of their efficacy affects their instructional practices and the achievement levels that students reach in STEM disciplines. As such, the primary guiding research question in this case was framed as follows: In what ways do elementary educators articulate their experiences fostering engagement and motivation in students during STEM activities? Data collection for …


The Protective Factors Of Trauma-Informed Care For Parents With Autistic Children, Carolynn J. Redd-Recksiek Jul 2025

The Protective Factors Of Trauma-Informed Care For Parents With Autistic Children, Carolynn J. Redd-Recksiek

Doctoral Dissertations and Projects

The purpose of this current phenomenological study is to understand the experience of parents with autistic children and their lack of trauma-informed care from direct care providers in Northern Utah. This study is guided by trauma-informed theory, which is a model of care delivery created by Maxine Harris and Roger D. Fallot (2001). Trauma-informed care recognizes how adverse experiences can impact a person and have a negative impact on the health and well-being of that person and how those negative experiences have a direct impact on the health and well-being of the family, which directly impacts the health and well-being …


Understanding The Willingness Of Christian Ethnic Minority Student-Athletes To Seek On-Campus Mental Health Services: A Mixed Methods Approach, Benael J. John-Rose Jul 2025

Understanding The Willingness Of Christian Ethnic Minority Student-Athletes To Seek On-Campus Mental Health Services: A Mixed Methods Approach, Benael J. John-Rose

Doctoral Dissertations and Projects

Romans 12:1 tells Christians that their unique physical abilities are gifts from God that should be used to honor Him (New International Version Bible, 1978/2011). Christian racial/ethnic minority student-athletes (CMSAs) often navigate complex intersections of spirituality, identity, and stigma in relation to mental health. Despite growing research in biopsychosocial-spiritual (BPSS) models, CMSAs remain underrepresented in mental health literature. This mixed-methods study explored the willingness of CMSAs to seek on-campus mental health services at a public university in the Southwestern United States. Data was collected through a web-based survey (N = 20) and semi-structured interviews with a subset of participants (N …


Predicting School Culture From Teacher Experience And Funding: A Predictive Correlational Study, Bailey D. Keller Jul 2025

Predicting School Culture From Teacher Experience And Funding: A Predictive Correlational Study, Bailey D. Keller

Doctoral Dissertations and Projects

The purpose of this quantitative, predictive correlational study is to understand how accurately the perception of school climate can be predicted from a linear combination of special education teachers’ years of teaching experience and supplemental state and federal funding allocated to teachers in the special education setting. The participants were drawn from a convenience sample of public school special education teachers located in a large school district in a southern state of the United States during the 2024-2025 school year. The setting for this research is a collection of campuses representing the work environments of the participants sampled. The My …


Unpacking Entrepreneurial Ecosystem Elements: Insights Into Drivers Of Entrepreneurial Activity, Mohamed Yacine Haddoud, Samah Souleh, Omaima Munawar Albadry, Saeyeon Roh, Adah Kole Emmanuel Onjewu Jul 2025

Unpacking Entrepreneurial Ecosystem Elements: Insights Into Drivers Of Entrepreneurial Activity, Mohamed Yacine Haddoud, Samah Souleh, Omaima Munawar Albadry, Saeyeon Roh, Adah Kole Emmanuel Onjewu

Plymouth Business School

Thriving entrepreneurial ecosystems (EEs) are instrumental in new enterprise creation and growth, as they provide vital support for entrepreneurial activity. However, as this support may be context-specific, the existing literature has yet to capture the contextual factors that shape the contributions of EEs. To address this inertia, a fuzzy analytical hierarchy process (FAHP) is employed, which examines the influence of ecosystem factors on new venture development in two key MENA countries, namely Algeria and Saudi Arabia. The findings indicate that physical, commercial, and legal infrastructure are important factors for EEs in both countries. Nevertheless, there are intriguing differences in the …


Greenhouse Evaluation Of Great Plains Native Grasses And Forbs Tolerance To Postemergence Herbicides Used For Roadside Weed Control, Rachel C. Woody-Pumford, Matthew B. Bertucci, Mike D. Richardson, Dirk Philipp, Hannah E. Wright-Smith Jul 2025

Greenhouse Evaluation Of Great Plains Native Grasses And Forbs Tolerance To Postemergence Herbicides Used For Roadside Weed Control, Rachel C. Woody-Pumford, Matthew B. Bertucci, Mike D. Richardson, Dirk Philipp, Hannah E. Wright-Smith

Horticulture Faculty Publications and Presentations

To combat the decline in North American grasslands and prairies, innovative strategies to establish new native grass and forb plantings must be considered. Integrated vegetation management entails the use of many practices to cultivate desirable vegetation along roadsides, including mowing, applying herbicides, burning, and replanting. Currently, only a limited selection of postemergence herbicides are available to improve native plant establishment along roadsides. A greenhouse herbicide screen that included four postemergence herbicides registered for use on Conservation Reserve Program (CRP) acres and rights-of-way was conducted to test their safety for use on four native grasses (big bluestem, buffalograss, sideoats grama, and …


Exploring Biblical Foundations In Biology, Keith Snyder Phd Jul 2025

Exploring Biblical Foundations In Biology, Keith Snyder Phd

The Journal of Biblical Foundations of Faith and Learning

Biologists have one of the most challenging areas of study due to the breadth of topics. Biology literally encompasses all life. Since life is based on chemical principles, which in turn are based on physical laws, we need to understand this panorama of science. Because academia in the US has pigeon-holed so much of our education, students are often unable to see the true integration of all aspects of life, resulting in a warped understanding of the interrelated complexity of our God’s creation. It is our duty to show how this intertwining of science and faith more fully represents God’s …


Scorpions Of The Horn Of Africa (Arachnida: Scorpiones). Part Xli. Pandinops Sahil Sp. N. From Somaliland (Scorpionidae), František Kovařík Jul 2025

Scorpions Of The Horn Of Africa (Arachnida: Scorpiones). Part Xli. Pandinops Sahil Sp. N. From Somaliland (Scorpionidae), František Kovařík

Euscorpius

Pandinops sahil sp. n. from Somaliland is described and compared with other species of the genus, fully complemented with color photos of specimens of both sexes of the new species, as well as of their habitat. Pandinops bambii Rossi, 2017 is synonymyzed with Pandinops turieli Kovařík, 2016, syn. n. A key for the species of Pandinops and a map of the distribution of the genus are provided.


Securing Ai-Generated Code, Andreas E. Nelson Jul 2025

Securing Ai-Generated Code, Andreas E. Nelson

Scholarly Horizons: University of Minnesota, Morris Undergraduate Journal

The increasing use of AI for code generation presents significant security challenges, as these tools often lack inherent security awareness and can produce vulnerable code. This paper investigates these security risks, outlining common types of vulnerabilities (such as injection flaws and improper resource handling) found in AI-generated code. It further explores and evaluates mitigation techniques aimed at im-proving code security, including model fine-tuning and adversarial strategies like Security Verifier Enhanced Neural Steering (SVEN). Findings indicate that while current methods offer promising ways to reduce vulnerabilities, ongoing research and development are crucial for the secure and responsible deployment of AI in …


La Lutte Pour Les Droits Des Femmes Africaines: Le Womanisme Dans Taafe Fanga, Elizabeth Davis Jul 2025

La Lutte Pour Les Droits Des Femmes Africaines: Le Womanisme Dans Taafe Fanga, Elizabeth Davis

Scholarly Horizons: University of Minnesota, Morris Undergraduate Journal

Dans cette thèse, j'analyserai le film Taafe Fanga (Pouvoir de Pagne en français), un film de 1997 du Mali, réalisé par Adama Drabo. Le film suit l'histoire du village de Yanda où des femmes, avec l'aide d'un masque qui invoque la peur dans des hommes, changent des rôles de genre, leur permettent de prendre le rôle masculin et dominant et mettent des hommes dans les rôles que les femmes tenaient avant. J'examinerai ce film d'un angle womaniste. J’affirme que, bien que les femmes dans le film d'Adama Drabo qui s'appelle Taafe Fanga luttent pour les droits des femmes, ce n'est …


Inappropriate Attire: Fashion, Nationality, And Shame In Quicksand And Pachinko, Minyoung Park Jul 2025

Inappropriate Attire: Fashion, Nationality, And Shame In Quicksand And Pachinko, Minyoung Park

CLCWeb: Comparative Literature and Culture

In her article, Minyoung Park examines how fashion in Quicksand by Nella Larsen and Pachinko by Min Jin Lee functions not simply as a visual strategy for passing but as a site where the wearers’ conflicting feelings—shame, desire, and defiance—emerge and persist. Rather than evaluating the success or failure of passing, the article shifts focus to the process of dressing—selecting, maintaining, and reflecting on clothing—through which identity is negotiated and feelings are embodied. The protagonists, Helga and Sunja, often dismissed as failures, are reconsidered as figures whose attention to their inappropriate or excessive fashion reveals their emotional labor and strenuous …


Spartanburg County School Integration Project: Bob Coleman And John Keith Interview, Bob Coleman, John Keith, Clayton Whisnant, Dallas Green, Wade Toth Jul 2025

Spartanburg County School Integration Project: Bob Coleman And John Keith Interview, Bob Coleman, John Keith, Clayton Whisnant, Dallas Green, Wade Toth

Oral History Interviews

Spartanburg County School Integration Project

Narrators: Bob Coleman (BC) and John Keith (JK)

Interviewers: Dr. Clayton Whisnant (CW)

Dallas Green (DG) and Wade Toth (WT)

at Wofford College

July 21, 2025


Insights Into Marine Biological Responses To Icelandic Glacial Outburst Floods From Remote Sensing Data, Cornelius Kaspar Jul 2025

Insights Into Marine Biological Responses To Icelandic Glacial Outburst Floods From Remote Sensing Data, Cornelius Kaspar

School of Geography, Earth and Environmental Sciences Theses

Cryospheric change has altered discharge patterns of the subglacial Skaftá cauldrons and Grímsvötn volcano beneath the Vatnajökull ice cap, SE Iceland (64.4220° N, 16.7902° W) at least since 1940. Jökulhlaup (glacial outburst floods) frequency has increased but their magnitude has decreased. This study examines jökulhlaup effects on the marine environment at the Gígjukvísl, Skaftá, and Kúðafljót estuaries. Remote sensing data integrated in situ, observational, and modelled data to analyse sea surface salinity (1/8° resolution), temperature (0.05° resolution), and observational chlorophyll-a data (1 km² resolution). Covering 11 jökulhlaups in Gígjukvísl/Skaftá and seven in Kúðafljót, a systematic response emerged in residual data. …


A Simple Action Reduces High-Fat Diet Intake And Obesity In Mice, M. R. Barrett, Y. Pan, C. L. Murrell, E. O. Karolczak, J. Wang, L. Z. Fang, J. M. Thompson, Y.-H. Chuang, E. Casey, J. E. Czarny, W. L. So, A. Reichenbach, R. Stark, H. Taghipourbibalan, S. R. Penna, K. B. Mccullough, S. R. Westbrook, G. C. Basu, B. Matikainen-Ankney, V. A. Cazares, K. Delevich, Wambura C. Fobbs, S. E. Maloney, A. S. Hickey, J. E. Mccutcheon, Z. B. Andrews, M. C. Creed, M. J. Krashes, A. V. Kravitz Jul 2025

A Simple Action Reduces High-Fat Diet Intake And Obesity In Mice, M. R. Barrett, Y. Pan, C. L. Murrell, E. O. Karolczak, J. Wang, L. Z. Fang, J. M. Thompson, Y.-H. Chuang, E. Casey, J. E. Czarny, W. L. So, A. Reichenbach, R. Stark, H. Taghipourbibalan, S. R. Penna, K. B. Mccullough, S. R. Westbrook, G. C. Basu, B. Matikainen-Ankney, V. A. Cazares, K. Delevich, Wambura C. Fobbs, S. E. Maloney, A. S. Hickey, J. E. Mccutcheon, Z. B. Andrews, M. C. Creed, M. J. Krashes, A. V. Kravitz

Psychology Faculty Works

Diets that are high in fat cause overeating and weight gain in multiple species of animals, suggesting that high dietary fat is sufficient to cause obesity. However, high-fat diets are typically provided freely to animals in obesity experiments, so it remains unclear whether high-fat diets would still cause obesity if these diets required more effort to obtain. We hypothesized that unrestricted access to high-fat diets is important for these diets to induce overeating and that requiring mice to perform small amounts of work to obtain a high-fat diet would reduce calorie intake and associated weight gain. To test this hypothesis, …


Thrombocytopenia In Patients With Plasmodium Vivax In Colombia Is Associated With Anti-Phosphatidylserine Autoantibodies And Il-6, Ifnγ, Il-10 And Tgf-Β, María Camila Velasco-Pareja, Catalina Tovar-Acero, Miriam E. Cantero Guevara, Ana Rodriguez, Juan Rivera-Correa, María Fernanda Yasnot-Acosta Jul 2025

Thrombocytopenia In Patients With Plasmodium Vivax In Colombia Is Associated With Anti-Phosphatidylserine Autoantibodies And Il-6, Ifnγ, Il-10 And Tgf-Β, María Camila Velasco-Pareja, Catalina Tovar-Acero, Miriam E. Cantero Guevara, Ana Rodriguez, Juan Rivera-Correa, María Fernanda Yasnot-Acosta

Publications and Research

Plasmodium vivax is the most widely distributed human protozoan in the world. It is a causative agent of malaria, with thrombocytopenia being a frequent complication. This study aimed to evaluate the effect of P. vivax infection on plasma cytokine/chemokine levels and anti-phosphatidylserine (anti-PS) autoantibodies, to explore their potential role in thrombocytopenia during P. vivax malaria in Córdoba, Colombia. We included patients with P. vivax malaria and thrombocytopenia (MT); patients with malaria without thrombocytopenia (M) and healthy controls (HC). Plasma cytokines/chemokines (IL-2, IL-4, IL-1β, TNF-α, IL-17A, IL-6, IL-10, IFNγ, IL-12p70, TGF-β1/IP-10, MCP-1, IL-8) were quantified. Evaluation of autoantibodies was performed by …


Ethical Implications Of Being A Holobiont, Scott F. Gilbert Jul 2025

Ethical Implications Of Being A Holobiont, Scott F. Gilbert

Biology Faculty Works

Developmental plasticity and holobiont theory have undermined the normative concepts of biological individuality. However, such traditional ideas of biological individuality have helped define and support Western ethical views into the 21st century. Guided by some of the ethical formulae of Simone Weil, Hans Jonas, and Alastair MacIntyre, this essay attempts to outline some possible trajectories for an ethics that is bounded by these new biological paradigms of environmental agency. Specifically, the ecological developmental biology concepts of plasticity and holobiont theory permit the “ethics of attention” to focus on the partnerships of living beings. Highlighting environmentally integrated life cycles and their …


Algorithmic Optimization Of Filter Bank: Harnessing Rapid Convergence And Its Applications, Keerthana B Ms Jul 2025

Algorithmic Optimization Of Filter Bank: Harnessing Rapid Convergence And Its Applications, Keerthana B Ms

Theses and Dissertations

A novel optimization framework is proposed for the design of both uniform and non-uniform filter banks, aimed at improving the accuracy and computational efficiency of biomedical signal classification tasks, with a particular emphasis on the detection of sleep disorders and Alzheimer’s disease.The proposed algorithm is grounded in multirate signal processing theory and aims to achieve Near Perfect Reconstruction (NPR) with minimal computational overhead. The process begins with the optimization of a uniform cosine-modulated filter bank (CMFB), achieved through iterative frequency-domain analysis and parameter tuning. This is followed by the derivation of a non-uniform filter bank via selective merging of bandpass …


Polylactic Acid (Pla)-Based Multifunctional And Biodegradable Nanocomposites And Their Applications, Md Shariful Islam, G. M. Fazley Elahee, Xiong (Bill) Yu, Rigoberto Castillo Advincula, Changyong (Chase) Cao Jul 2025

Polylactic Acid (Pla)-Based Multifunctional And Biodegradable Nanocomposites And Their Applications, Md Shariful Islam, G. M. Fazley Elahee, Xiong (Bill) Yu, Rigoberto Castillo Advincula, Changyong (Chase) Cao

Faculty Scholarship

Polylactic acid (PLA)-based nanocomposites are emerging as multifunctional, biodegradable materials, offering sustainable alternatives to petroleum-based plastics. This review examines recent advancements in PLA nanocomposites, focusing on enhanced mechanical strength, thermal stability, and biodegradability achieved through nanofillers like metallic particles, carbon-based materials, and ceramics. Techniques such as in situ polymerization, melt mixing, and electrospinning enable application-specific improvements. PLA's limitations, including brittleness and low barrier properties, are addressed to support diverse applications: in packaging (e.g., extended shelf life), biomedicine (e.g., degradable implants), and electronics (e.g., flexible devices). Despite challenges with filler dispersion and thermal resistance, continued innovations expand PLA's potential across multiple …


Algorithmic Optimization Of Filter Bank: Harnessing Rapid Convergence And Its Applications, Keerthana B Jul 2025

Algorithmic Optimization Of Filter Bank: Harnessing Rapid Convergence And Its Applications, Keerthana B

Theses and Dissertations

A novel optimization framework is proposed for the design of both uniform and non-uniform filter banks, aimed at improving the accuracy and computational efficiency of biomedical signal classification tasks, with a particular emphasis on the detection of sleep disorders and Alzheimer’s disease. The proposed algorithm is grounded in multirate signal processing theory and aims to achieve Near Perfect Reconstruction (NPR) with minimal computational overhead. The process begins with the optimization of a uniform cosine-modulated filter bank (CMFB), achieved through iterative frequency-domain analysis and parameter tuning.

This is followed by the derivation of a non-uniform filter bank via selective merging of …


A Comprehensive Deep Learning System With Mgrf Modeling For Predicting Breast Cancer Response To Neoadjuvant Chemotherapy, Ahmed Sharafeldeen, Fatma Taher, Norah Saleh Alghamdi, Eman Alnaghy, Reham Alghandour, Khadiga M. Ali, Sameh Shamaa, Abdelrahman Gamal, Mohammed Ghazal, Sohail Contractor, Ayman El-Baz Jul 2025

A Comprehensive Deep Learning System With Mgrf Modeling For Predicting Breast Cancer Response To Neoadjuvant Chemotherapy, Ahmed Sharafeldeen, Fatma Taher, Norah Saleh Alghamdi, Eman Alnaghy, Reham Alghandour, Khadiga M. Ali, Sameh Shamaa, Abdelrahman Gamal, Mohammed Ghazal, Sohail Contractor, Ayman El-Baz

All Works

Accurate prediction of breast cancer (BC) response to neoadjuvant chemotherapy (NAC) is critical for tailoring treatment strategies and improving patient outcomes. This study introduces a novel deep learning-based framework that integrates multi-parametric magnetic resonance imaging (MRI) (i.e., T1, T2, STIR, and DWI), along with clinical and molecular subtype markers, to classify tumor response into pathological complete response (pCR), partial response (PR), and stable disease (SD). First, tumor regions are delineated across MRI modalities and then modeled using a translation-invariant Markov-Gibbs random field (MGRF) with analytical parameter estimation to capture modality-specific spatial appearance patterns correlated with NAC response. Subsequently, diffusion-weighted MRI …


Tlr4 Asp299gly Snp (Rs4986790) Protects From Periodontal Inflammatory Destruction By Altering Tlr4 Susceptibility To Lps Stimulation, Franco Cavalla, Cláudia Cristina Biguetti, Ariadne Letra, Renato Silva, Alexandre R. Vieira, Franz J. Strauss, Gustavo P. Garlet Jul 2025

Tlr4 Asp299gly Snp (Rs4986790) Protects From Periodontal Inflammatory Destruction By Altering Tlr4 Susceptibility To Lps Stimulation, Franco Cavalla, Cláudia Cristina Biguetti, Ariadne Letra, Renato Silva, Alexandre R. Vieira, Franz J. Strauss, Gustavo P. Garlet

School of Podiatric Medicine Publications

Simple Summary

Periodontitis is a common disease that affects the gums and the bone supporting the teeth, often leading to tooth loss. It results from a complex interaction between bacteria and the body’s immune response. Some people are more susceptible than others, and genetics may play a role. In this study, we focused on a genetic variation (called a polymorphism) in a gene known as TLR4, which helps the immune system recognize harmful bacteria. We examined over 1400 individuals from different populations and found that people carrying this specific variation, known as Asp299Gly, were less likely to develop severe periodontal …


Global Incidence Of Female Birdsong Is Predicted By Territoriality And Biparental Care In Songbirds, Karan J. Odom, Marcelo Araya-Salas, Lauryn Benedict, Kristi Lim, James Dale, Wesley H. Webb, Catherine Sheard, Joseph A. Tobias, Gregory F. Ball, Michelle L. Hall, Naomi E. Langmore, Michael S. Webster, Katharina Riebel Jul 2025

Global Incidence Of Female Birdsong Is Predicted By Territoriality And Biparental Care In Songbirds, Karan J. Odom, Marcelo Araya-Salas, Lauryn Benedict, Kristi Lim, James Dale, Wesley H. Webb, Catherine Sheard, Joseph A. Tobias, Gregory F. Ball, Michelle L. Hall, Naomi E. Langmore, Michael S. Webster, Katharina Riebel

Pacific Faculty Work

Pronounced sexual dimorphism is generally assumed to evolve through sexual selection for elaborate male traits. However, there is increasing evidence that sexual dimorphism in traits such as birdsong may also evolve through loss of elaboration in females, but the evolutionary drivers underlying this process are obscure. Here we analyse ecological and natural history traits for over 1300 songbird species and show that increased female song incidence and elaboration are most directly associated with year-round territoriality, biparental care, and large body size. Phylogenetic path analysis indicates that mating system and breeding latitude primarily have indirect effects on female song evolution. Stable, …


Parents’ Experiences With Their Child’S Psychotherapy And Mental Illness, Valerie Marsman Jul 2025

Parents’ Experiences With Their Child’S Psychotherapy And Mental Illness, Valerie Marsman

Walden Dissertations and Doctoral Studies

Low parental engagement—especially among fathers and ethnic minority groups like Latinx parents—in child psychotherapy increases the risk of treatment dropout, behavioral issues, and poorer outcomes, contributing to persistent disparities. More research was needed on perceptual barriers and facilitators to parental engagement such as attitudes, beliefs, and expectations. The purpose of this study was to gain an in-depth understanding of parents’ experiences with their child’s psychotherapy and mental illness to facilitate parental engagement in services that support the child. An interpretative phenomenological approach and multiperspectival focus group design were used to illuminate each participant’s voice and explore overarching themes. Hill’s theory …


Bold New Bioweapons: Part 1 — The Burdens Of Detection And Attribution, James Giordano Jul 2025

Bold New Bioweapons: Part 1 — The Burdens Of Detection And Attribution, James Giordano

Strategic Insights

This commentary, Pt. 1 of the Bold New Bioweapons series, examines how advances in gene editing, synthetic biology, and artificial intelligence are reshaping the biological weapons threat landscape and challenging the effectiveness of the Biological Weapons Convention (BWC). Dr. Giordano argues that decentralized research ecosystems, AI-enabled pathogen design, and dual-use biotechnology complicate detection, attribution, and deterrence. Emerging techniques can produce synthetic or modified biological agents that evade traditional surveillance systems and blur distinctions between legitimate research and weaponization. The absence of clear adjudication mechanisms within the BWC creates governance gaps exploitable by state and non-state actors. The article emphasizes that …


The Effect Of Tranexamic Acid On Blood Coagulation In Primary Total Hip Arthroplasty Using Rotational Thromboelastometry: A Randomized Controlled Trial, Uzung Yoon, David Beausang, Elia Elia, Marc Torjman, Jeffrey Mojica, James J. Purtill, David Nazarian, P. Maxwell Courtney, Yoogoo Kang Jul 2025

The Effect Of Tranexamic Acid On Blood Coagulation In Primary Total Hip Arthroplasty Using Rotational Thromboelastometry: A Randomized Controlled Trial, Uzung Yoon, David Beausang, Elia Elia, Marc Torjman, Jeffrey Mojica, James J. Purtill, David Nazarian, P. Maxwell Courtney, Yoogoo Kang

Department of Anesthesiology Faculty Papers

BACKGROUND: Tranexamic acid (TXA), is commonly administered prophylactically to reduce blood loss in patients undergoing total hip arthroplasty (THA). However, its effect has never been studied. We hypothesized that no difference exists in the degree of fibrinolysis and blood loss between patients receiving prophylactic TXA and placebo.

METHODS: This double-blinded randomized-controlled trial included 50 patients undergoing primary THA in 2021-2023. Clinicaltrials.gov (NCT03897621). Rotational-thromboelastometry (ROTEM) were performed to test blood coagulability using non citrated whole blood (NATEM) and blood treated with TXA (T-APTEM). The intervention group received TXA intravenously. The placebo group received 0.9% sodium chloride solution. The primary outcome measure …


Injury And Illness: An Analysis Of Team Usa Athletes At The 2024 Winter Youth Olympic Games, Ashley N. Triplett, Eric G. Post, Travis Anderson, Olivia Samson, Alexis D. Gidley, Francisco Silva, Lea Thomann, Amber T. Donaldson, Jonathan T. Finnoff, Eric L. Dugan, Jeffrey S. Shilt, William M. Adams Jul 2025

Injury And Illness: An Analysis Of Team Usa Athletes At The 2024 Winter Youth Olympic Games, Ashley N. Triplett, Eric G. Post, Travis Anderson, Olivia Samson, Alexis D. Gidley, Francisco Silva, Lea Thomann, Amber T. Donaldson, Jonathan T. Finnoff, Eric L. Dugan, Jeffrey S. Shilt, William M. Adams

Department of Pediatrics Faculty Papers

BACKGROUND: Injury and illness surveillance is essential for understanding the relative risks of sports participation to develop effective strategies to optimize athlete health, wellness, and performance. Epidemiological studies examining injuries and illnesses among Team USA youth athletes are limited, particularly among athletes competing in Winter sports. The purpose of this study was to characterize the injury and illness incidence rate among Team USA athletes participating in the 2024 Winter Youth Olympic Games (YOG).

METHODS: Injuries and illnesses among 101 Team USA youth athletes (40.6% female; age, 17 ± 1 years) were prospectively documented. Injury and illness prevalence, and incidence rate …


School Counselors’ Perceptions On Providing Mental Health Services In Schools, Kimberly Davis Jul 2025

School Counselors’ Perceptions On Providing Mental Health Services In Schools, Kimberly Davis

Walden Dissertations and Doctoral Studies

The increasing prevalence of mental health concerns among students in the United States has amplified the demand for comprehensive school-based mental health services. School counselors are often positioned as frontline providers of this support, yet research suggests they face numerous systemic and role-related challenges. This qualitative phenomenological study was conducted to explore school counselors’ perceptions of their roles in providing mental health services, the barriers they encounter, and the ways in which self-efficacy is shaped by these experiences. Ten school counselors from diverse school settings participated in semistructured interviews. Thematic analysis revealed five central themes: (a) roles and responsibilities, (b) …


Investigating The Necessity Of Adaptive Radiotherapy In Tomotherapy Of Head And Neck Cancer Patients, Ali Chaparian, Mahsa Kianinia, Mahnaz Roayaei, Nadia Najafizade, Abolfazl Kanani, Leili Mahani, Hamidreza Nourzadeh Jul 2025

Investigating The Necessity Of Adaptive Radiotherapy In Tomotherapy Of Head And Neck Cancer Patients, Ali Chaparian, Mahsa Kianinia, Mahnaz Roayaei, Nadia Najafizade, Abolfazl Kanani, Leili Mahani, Hamidreza Nourzadeh

Department of Radiation Oncology Faculty Papers

BACKGROUND: Anatomical variations that occur during radiation therapy in head and neck cancer (HNC) patients can lead to significant dosimetric changes. The purpose of this study is to evaluate dosimetric and volume changes in key anatomical structures for different treatment sites in HNC patients, and to determine the percentage of patients who need adaptive radiotherapy (ART) per treatment site.

METHODS: A total of 1,740 megavoltage computed tomography (MVCT) images from 58 HNC patients treated with helical tomotherapy (HT) were exported to the PreciseART™ (Accuray) software. Volume changes in the planning target volume (PTV) and the organs at risk (OARs) in …