Digital Commons Network^™

Where Are The Criminologists?: The Persistent Absence Of The Field In Genocide Research, Grace Allbaugh, Susan A. Woollen, Jacqueline L. Schneider, Joanne Savage

Genocide Studies and Prevention: An International Journal

The rallying cry of “Never Again” was heard worldwide after the Nazis’ annihilation of Jews and other victims were discovered after WWII. The global community promised that the crime of genocide would be prevented and signatory parties of the United Nations Convention on the Prevention and Punishment of Genocide (December 9, 1948) would do everything in their power to prevent another Holocaust from occurring. Unfortunately the “crime of all crimes” remains an almost permanent fixture in international news while signatory parties remain reluctant to call the ongoing conditions genocide. The field of genocide studies is built upon an interdisciplinary field …

Lessons In Longevity From Blood Stem Cells Under Protein Stress, André Catic

Center on Aging Staff Publications

Blood stem cells are among the body's longest-living cells despite being highly vulnerable to proteotoxic damage, which accelerates their aging. To maintain protein homeostasis (proteostasis), hematopoietic stem cells (HSCs) employ mechanisms such as reduced translation rates, high chaperone activity, autophagy, and selective protein degradation. These strategies mitigate protein misfolding, maintain quiescence, and preserve regenerative potential. Disruptions in proteostasis can lead to the elimination of impaired HSCs through differentiation or apoptosis, ensuring the integrity of the stem cell pool. Due to the systemic impact of the blood on aging and its experimental and clinical accessibility, investigating HSC proteostasis provides insights into …

Optimization Of Formula, Stability Testing, And Antioxidant Activity Of Clay Masks As Skin Moisturizers, Naniek Widyaningrum, Agung Dwi Anggoro Bhakti, Alghafiqy Harya Evan Maulana, Amalia Safitri, Adinda Fajrah Ramadhani, Anisa Febriani, Anggit Naufal Hanafi, Thendi Abdul Arief

Pharmaceutical Sciences and Research

Clay masks are cosmetic formulations designed to adhere closely to the skin, effectively lifting contaminants, cleansing the face, and absorbing impurities. We made a clay mask containing active ingredients such as niacinamide, alpha arbutin, ceramide, and hyaluronic acid. A careful selection of ingredients is essential for ensuring safety and mitigating potential dermatological issues. This study aimed to evaluate the physical characteristics, stability, primary irritation potential, and moisturizing efficacy of this clay mask formulation. Kaolin and bentonite are the primary base materials. The research included formulation optimization and physical stability testing using a cycling test, where each cycle was conducted over …

Elevated Nr2f1 Underlies The Persistence Of Invasive Disease After Treatment Of Braf-Mutant Melanoma, Manoela Tiago, Timothy J. Purwin, Casey D. Stefanski, Renaira Oliveira Da Silva, Mitchell E. Fane, Yash Chhabra, Jelan I. Haj, Jessica L. F. Teh, Rama Kadamb, Weijia Cai, Sheera Rosenbaum, Vivian Chua, Nir Hacohen, Michael A. Davies, Jessie Villanueva, Inna Chervoneva, Ashani T. Weeraratna, Dan A. Erkes, Claudia Capparelli, Julio A. Aguirre-Ghiso, Andrew E. Aplin

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Despite the success of targeted inhibitors in cutaneous melanoma, therapeutic responses are limited by the aged tumor microenvironment and drug-tolerant residual cells. Given the similarities between drug tolerance and cellular dormancy, we studied the dormancy marker, nuclear receptor subfamily 2 group F member 1 (NR2F1), in response to BRAF-V600E inhibitors (BRAFi) plus MEK inhibitors (MEKi) in BRAF-mutant melanoma models. Transcriptomic analysis of melanoma patient samples treated with BRAFi + MEKi showed increased NR2F1. NR2F1 was highly expressed in the drug-tolerant invasive cell state of minimal residual disease in patient-derived and mouse-derived xenografts on BRAFi + MEKi. NR2F1 over-expression was sufficient …

Epigenomic Diagnosis And Prognosis Of Acute Myeloid Leukemia., Francisco Marchi, Vivek M. Shastri, Richard J. Marrero, Nam H K Nguyen, Antonella Öttl, Ann-Kathrin Schade, Marieke Landwehr, Olga Krali, Jessica Nordlund, Matin Ghavami, Fernando Sckaff, Vikash K. Mansinghka, Xueyuan Cao, William Slayton, Petr Starostik, Christopher R. Cogle, Raul C. Ribeiro, Jeffrey E. Rubnitz, Jeffery Klco, Abdelrahman Elsayed, Alan S. Gamis, Timothy J. Triche, Rhonda Ries, E Anders Kolb, Richard Aplenc, Todd Alonzo, Stanley Pounds, Soheil Meshinchi, Jatinder K. Lamba

Manuscripts, Articles, Book Chapters and Other Papers

Despite the critical role of DNA methylation, clinical implementations harnessing its promise have not been described in acute myeloid leukemia. Utilizing DNA methylation from 3314 leukemia patient samples across 11 harmonized cohorts, we describe the Acute Leukemia Methylome Atlas, which includes robust models capable of accurately predicting AML subtypes. A genome-wide prognostic model as well as a targeted panel of 38 CpGs significantly predict five-year survival in our pediatric and adult test cohorts. To accelerate rapid clinical utility, we develop a specimen-to-result protocol that uses long-read nanopore sequencing and machine learning to characterize patients' whole genomes and epigenomes. Clinical validation …

In Silico Prediction Of Cytotoxic T-Cell Epitopes From Helicobacter Pylori Virulence Factors Using An Immunoinformatics Approach, Demy Valerie Chacon, Kiana Alika Co, Daphne Noreen Enriquez, Aubrey Love Labarda, Reanne Eden Manongsong, Edward Kevin B. Bragais

Biology Faculty Publications

Background: Helicobacter pylori infects approximately half of the global population, leading to gastric and duodenal ulcers. Despite the availability of antibiotics, challenges such as patient reluctance, high treatment costs, and antibiotic resistance limit their effectiveness, making vaccination a promising alternative. This study used immunoinformatics to identify candidate epitopes for a multiepitope vaccine construct against H. pylori.

Material and methods: The protein variability server was utilized for conservation analysis. The epitopes were screened for antigenicity, allergenicity, toxicity, cross-reactivity, and population coverage. Selected epitopes were docked with their corresponding human leukocyte antigen (HLA) alleles, and thermodynamic quantities were determined. Five virulence …

A Phase I Trial Of Evorpacept, Lenalidomide And Rituximab For Patients With B-Cell Non-Hodgkin Lymphoma, Paolo Strati, Lei Feng, Andrey Tyshevich, Darya Shavronskaya, Julia Alesse, Noel English, Elizabeth Sheehan, Nikita Syzrantsev, Alexander Nesmelov, Tony Z Zhuang, Dai Chihara, Jason R Westin, Sairah Ahmed, Luis E Fayad, Jared Henderson, Kylie Dent, Elizabeth Mcchesney, Sattva S Neelapu, Christopher R Flowers

Faculty, Staff and Student Publications

Introduction: SIRPα+ macrophages can mediate resistance to lenalidomide and rituximab (R2) in patients with B-cell non-Hodgkin lymphoma (B-NHL). Evorpacept (ALX148) is a novel CD47 blocker that abrogates interactions between lymphoma cells and SIRPα+ macrophages.

Methods: Adult patients with B-NHL who had received at least 2 prior lines of systemic therapy were included in this single arm phase I study (NCT05025800). Evorpacept was administered intravenously (IV), in a 28-day cycle, until progression, at two dose levels (DL): 30 mg/Kg on day (D) 1 and D15 (DL1), or 60 mg/Kg on day 1 (DL2); rituximab 375 mg/m2 IV was given …

Optimizing Distributed Boundary Exchanges For Benchmarks, Solvers And Sparse Matrix Operations, Gerald Collom

Computer Science ETDs

Boundary exchanges dominate the cost of both stenciled codes and those that rely on sparse matrix operations. The performance of large boundary exchanges is limited by synchronization overheads and injection bandwidth limitations. Irregular boundary exchanges incur additional overheads due to the large number of required messages. This thesis investigates multiple methods for improving the performance and scalability of both Cartesian and irregular boundary exchanges. Since boundary exchanges are typically performed iteratively, persistent communication presents an opportunity for optimization by sharing and amortizing setup costs. Partitioned communication is also explored to increase asynchrony, reducing bottlenecks from synchronization overheads and data congestion. …

Exploring Immune System Through Computational Modeling: A Comprehensive Study Of Lymph Nodes And Immune Response Scaling, Vaccine Efficacy, And Large-Scale Extreme First Passage Time, Jannatul Ferdous

Computer Science ETDs

The adaptive immune response is a complex defense mechanism that develops over time to recognize and eliminate pathogens with remarkable precision and durability. This dissertation investigates the dynamics, scaling, and efficiency of the adaptive immune response through a synthesis of computational modeling, mathematical analysis, and agent-based simulations. First, we analyze the topology of the lymphatic network and investigate the T cell search time to find the lymph node that is containing the matching dendritic cell. Second we show how the scaling of lymph node number and volume with body mass, leads to scale-invariant search times for T cells locating antigen-bearing …

Cocoa Polyphenols Alter The Fecal Microbiome Without Mitigating Colitis In Mice Fed Healthy Or Western Basal Diets, Eliza C. Stewart, Mohammed F. Almatani, Marcus Hayden, Giovanni Rompato, Jeremy Case, Samuel Rice, Korry J. Hintze, Abby D. Benninghoff

Animal, Dairy, and Veterinary Science Student Research

Background/Objectives: Chronic inflammation and Western-style diets elevate colorectal cancer (CRC) risk, particularly in individuals with colitis, a feature of inflammatory bowel disease (IBD). Diets rich in polyphenol-containing functional foods, such as cocoa, may reduce gut inflammation and modulate the gut microbiome. This study investigated the impact of cocoa polyphenol (CP) supplementation on inflammation and microbiome composition in mice with colitis, fed either a healthy or Western diet, before, during, and after the onset of disease. We hypothesized that CPs would attenuate inflammation and promote distinct shifts in the microbiome, especially in the context of a Western diet. Methods: …

Nursing Turnover Based On Age, Race, And Gender In Community Hospitals In Michigan, Laura Lawhorn

Walden Dissertations and Doctoral Studies

Hospitals struggle to maintain nursing staff to meet patient needs for a population that requires continuous care and experiences multiple illnesses. The purpose of this quantitative study was to investigate the variations in reasons for leaving the nursing profession (dependent variable) based on age, race, and gender (independent variables) within community hospitals in Michigan. The theoretical framework for this study was the Nursing Neuman Systems Model, which posits that nursing comprises four key components: environment, individual, nursing practice, and health. A correlational research design was utilized to address the research question and analyze the relationships between the variables. The secondary …

Cell Type-Specific Purifying Selection Of Synonymous Mitochondrial Dna Variation, Caleb A Lareau, Patrick Maschmeyer, Yajie Yin, Jacob C Gutierrez, Ryan S Dhindsa, Anne-Sophie Gribling-Burrer, Sebastian Zielinski, Yu-Hsin Hsieh, Lena Nitsch, Veronika Dimitrova, Benan Nalbant, Frank A Buquicchio, Tsion Abay, Robert R Stickels, Jacob C Ulirsch, Patrick Yan, Fangyi Wang, Zhuang Miao, Katalin Sandor, Bence Daniel, Vincent Liu, Paul L Mendez, Petra Knaus, Manpreet Meyer, William J Greenleaf, Anshul Kundaje, Redmond P Smyth, Mathias Munschauer, Leif S Ludwig, Ansuman T Satpathy

Duncan NRI Faculty and Staff Publications

While somatic variants are well-characterized drivers of tumor evolution, their influence on cellular fitness in nonmalignant contexts remains understudied. We identified a mosaic synonymous variant (m.7076A > G) in the mitochondrial DNA (mtDNA)-encoded cytochrome c-oxidase subunit 1 (MT-CO1, p.Gly391=), present at homoplasmy in 47% of immune cells from a healthy donor. Single-cell multiomics revealed strong, lineage-specific selection against the m.7076G allele in CD8+ effector memory T cells, but not other T cell subsets, mirroring patterns of purifying selection of pathogenic mtDNA alleles. The limited anticodon diversity of mitochondrial tRNAs forces m.7076G translation to rely on wobble pairing, unlike the Watson-Crick-Franklin pairing …

Sleep Drive, Not Total Sleep Amount, Increases Seizure Risk, Vishnu Anand Cuddapah, Cynthia T Hsu, Fernanda Valle Sirias, Yongjun Li, Hrishit M Shah, Christopher Saul, Samantha Killiany, Camilo Guevara, Joy Shon, Zhifeng Yue, Gabrielle L Gionet, Mary E Putt, Amita Sehgal

Duncan NRI Faculty and Staff Publications

Sleep loss has been associated with increased seizure risk since antiquity. Using automated video detection of spontaneous seizures in Drosophila epilepsy models, we show that seizures worsen only when sleep restriction raises homeostatic "sleep drive," not simply when total sleep amount falls. This is supported by the paradoxical finding that acute activation of sleep-promoting circuits worsens seizures, because it increases sleep drive without changing sleep amount. Sleep-promoting circuits become hyperactive after sleep loss and are associated with increased whole-brain activity. During sleep restriction, optogenetic inhibition of sleep-promoting circuits to reduce sleep drive protects against seizures. Downregulation of the 5HT1A serotonin …

Cd45 And Cd148 Are Critically Involved In Neutrophil Recruitment And Function During Inflammatory Arthritis In Mice, Jan-Niklas Heming, Andreas Margraf, Karolina Najder, Giulia Germena, Mathis Richter, Anika Cappenberg, Katharina Henke, Bernadette Bardel, Lena Schemmelmann, Marina Oguama, Pia Lindental, Wida Amini, Jacqueline Sobocik, Georg Schett, Gerhard Krönke, Helena Block, Jan Rossaint, Oliver Soehnlein, Alexander Zarbock

Faculty, Staff and Student Publications

Neutrophils play a key role in autoimmune diseases like rheumatoid arthritis, contributing to tissue damage through rapid recruitment and activation. In this study, we investigated the regulatory properties of two receptor-like tyrosine phosphatases (RPTPs), CD45 and CD148, in inflammatory arthritis. Using an in vivo mouse model of K/BxN serum transfer-induced arthritis, we found that CD45 and CD148 feature distinct regulatory properties during inflammatory arthritis. CD45 is required for neutrophil infiltration, cytokine release, and reactive oxygen species production, whereas CD148 deficiency leads to a delayed onset of arthritis but unaltered overall neutrophil infiltration and reduced ROS production. Furthermore, we could demonstrate …

Glucose Metabolism And Its Direct Action In Cancer And Immune Regulation: Opportunities And Challenges For Metabolic Targeting, Bo-Syong Pan, Che-Chia Hsu, Hsin-En Wu, Yuan-Ru Chen, Xiaobo Zhou, Shu-Chi Wang, Chia-Yang Li, Hui-Kuan Lin

Faculty, Staff and Student Publications

Glucose metabolism is a pivotal hub for cellular energy production and the generation of building blocks that support cell growth, survival, and differentiation. Cancer cells undergo metabolic reprogramming to sustain rapid proliferation, survive in harsh microenvironments, and resist therapies. Beyond producing energy and building blocks to meet cancer cell demands, glucose metabolism generates numerous metabolites that serve as signaling molecules, orchestrating signaling pathways and epigenetic modifications that regulate cancer cell phenotypes and immunity. In this review, we discuss how glucose, through its metabolism and direct actions, influences diverse biological processes driving cancer progression and therapeutic resistance, while also exploring metabolic …

Treatment With Allogenic Mesenchymal Stromal Cells For Moderate To Severe Acute Respiratory Distress Syndrome: A Double-Blind, Placebo-Controlled, Multi-Center, Phase 2b Clinical Trial (Stat), Michael A Matthay, Hanjing Zhou, Aartik Sarma, Narges Alipanah-Lechner, Carolyn Hendrickson, Lucy Z Kornblith, Martin Schreiber, David Zonies, Akram Khan, Bryce Robinson, Nicholas J Johnson, Lorraine B Ware, Oscar Guillamondegui, Jonathan Casey, Laura Moore, Bela Patel, Lillian Kao, Charles E Wade, Erin Fox, Charles Cox, Farrakh Khawanja, Robier Aguillon Prada, Sami Hossri, Rachael Callcut, Timothy Albertson, Kevin L Delucchi, Melanie Mcmillan, Charles R Langelier, Shibani Pati, David H Mckenna, Carolyn Leroux, Carolyn S Calfee, Kathleen D Liu

Faculty, Staff and Student Publications

Background: Prior clinical trials established the safety, but not the efficacy of bone marrow-derived mesenchymal stromal cells (MSCs) in the acute respiratory distress syndrome (ARDS).

Methods: We conducted a prospective, double-blind, multi-center randomized phase 2b clinical trial of one dose of intravenous MSCs (10 x 106/kg predicted body weight) versus placebo in 120 ventilated patients with ARDS (PaO2/FiO2 < 250 mmHg). The primary endpoint was change in oxygenation index (OI) over 36 hours from baseline.

Findings: Enrollment began in January 2020. Due to the Coronavirus 2019 (COVID-19) pandemic, the majority of subjects (101/120, 84%) developed ARDS from COVID-19. There were no significant baseline differences in severity of illness between patients treated with MSCs and those who received …

2023-04-25 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Loss And Early Recovery Of Biomass And Soil Organic Carbon In Restored Mangroves After Paspalum Vaginatum Invasion In West Africa, Julio César Chávez Barrera, Juan Fernando Gallardo Lancho, Robert Puschendorf, Claudia Maricusa Agraz Hernández

School of Biological and Marine Sciences

Invasive plant species pose an increasing threat to mangroves globally. This study assessed the impact of Paspalum vaginatum invasion on carbon loss and early recovery following four years of restoration in a mangrove forest with Rhizophora racemosa in Benin. Organic carbon was quantified in the total biomass, including both aboveground and belowground components, as well as in the soil to a depth of −50 cm. In addition, soil gas fluxes of CO ₂, CH ₄, and N ₂O were measured. Three sites were evaluated: a conserved mangrove, a site degraded by P. vaginatum, and the same site …

Targeted Delivery Of Rapamycin Via Epidermal Growth Factor Receptors In Pancreatic Cancer Cells Inhibits Cell Proliferation And Induces Apoptosis, Adeolu S. Oluremi, Christofer Baldwin, Nickolas L. Gustavision, Mujeebat Bashiru, Adeniyi Nsiah Oyebade, Noureen Siraj, Raj Raghavendra Rao, N. Ali

Biomedical Engineering Faculty Publications and Presentations

Pancreatic cancer (PC) is aggressive and deadly; most PC cells overexpress an epidermal growth factor receptor (EGFR). EGFR-targeting peptide (GE11) was conjugated to gold nanoparticles (AuNPs) for delivering rapamycin (Rap), an mTOR inhibitor that reduces proliferation and induces apoptosis. Biophysical techniques confirmed the conjugation. Rap loading efficiency was 41.5%, with sustained release at a lower pH. Conjugates showed higher uptake in PANC-1 cells than unmodified AuNPs. It also inhibited proliferation and induced apoptosis via pathways involving reactive oxygen species, mitochondrial damage, and caspase activation. This approach represents a promising nanoparticle-based therapeutic strategy targeting PC cells, utilizing GE11-EGFR interactions to minimize …

Structural Variants: Mechanisms, Mapping, And Interpretation In Human Genetics, Shruti Pande, Moez Dawood, Christopher M Grochowski

Faculty, Staff and Students Publications

Structural variations (SVs) represent genomic variations that involve breakage and rejoining of DNA segments. SVs can alter normal gene dosage, lead to rearrangements of genes and regulatory elements within a topologically associated domain, and potentially contribute to physical traits, genomic disorders, or complex traits. Recent advances in sequencing technologies and bioinformatics have greatly improved SV detection and interpretation at unprecedented resolution and scale. Despite these advances, the functional impact of SVs, the underlying SV mechanism(s) contributing to complex traits, and the technical challenges associated with SV detection and annotation remain active areas of research. This review aims to provide an …

Effects Of The Gut Microbiota On Placental Angiogenesis And Intrauterine Growth In Gnotobiotic Mice, Reyan Coskun, Zenan L Chang, Athziri Marcial Rodríguez, Haoxin Liu, Jiye Cheng, Yael Alippe, Michael S Diamond, Jeffrey I Gordon

2020-Current year OA Pubs

Environmental causes of intrauterine growth restriction (IUGR) remain poorly characterized. Here, we compare germ-free (GF) and conventionally raised (CONV-R) mice to assess the effects of the gut microbiota on placental/fetal development at embryonic day (E)11.5 (end of placentation) and E17.5 (near term). Pregnancy- and microbiota-associated changes in gene expression occur along the gut, including those related to angiogenesis, while bacterial composition and fermentation activity remain stable. Placental weights at E11.5 and fetal weights at E17.5 are significantly reduced in GF animals. Compared to CONV-R dams, the GF maternal decidua exhibits similar vascular histomorphometric features at E11.5 and E17.5, and numbers …

Die Deutung Des Mimischen Ausdrucks, F. J. J. Buytendijk, Helmuth Plessner

Hannah Arendt Marginalia - All

Bonn : Cohen, 1925

Call #: BF511 .B89 1925

Contains marginalia, underlining, marginal lining and inscription

PDF information: 10 pages – 929 KB

Predictors Of Sleep Duration In Undergraduate Students Attending A Health Sciences University In Japan, Aaron M. Eakman, Yuki Kawakatsu, Miki Takahata, Daisuke Kudo, Shinji Satake, Toshiaki Sato

Internet Journal of Allied Health Sciences and Practice

Background: Inadequate sleep is a pressing public health concern contributing to absenteeism and poor school performance, especially in health sciences students. In this study we investigated the sleep quality and duration of undergraduate students in a prefectural university of health sciences program and explored factors explaining sleep duration (i.e., < 6 hours per night vs > 6 hours) using multiple variable logistic regression.

Method: This cross-sectional survey study included 369 nursing, occupational therapy and physical therapy students who completed Japanese versions of the Pittsburg Sleep Quality Index, in addition to well validated sleep-related and mental health-related assessments.

Results: We found just 11.7% of the …

14-Year Retrospective Review Of Audiology Graduate Admission Data: Comparative Analysis With Other First Professional Health Programs, Alyssa R. Needleman, Patricia A. Gaffney, Erica B. Friedland, Josiah Alamu

Internet Journal of Allied Health Sciences and Practice

Purpose: Demographic and cognitive data on students entering audiology programs is incomplete, and there is a lack of comparison among audiology students and those entering other first professional health (FPH) programs. This paper is the first of a multi-part series to provide evidence into the characteristics of the typical audiology student and their graduate outcomes. This is valuable for improving recruiting, admissions, retention, and success rates of audiology programs. A comprehensive descriptive analysis of admission criteria was performed for students who entered the NSU Doctor of Audiology (AuD) program over the last 14 years. Additionally, NSU admissions data was compared …

The Effect Of A Therapy Dog On Pressure Pain Threshold In Healthy Individuals, Lydia L. Haak, Rhonda L. Verdegan

Internet Journal of Allied Health Sciences and Practice

Purpose: Pain is the most common reason for healthcare consultation in the United States. Pain affects every area of life; biologically, psychologically, and socially. These three constructs make up every individual and thus contribute to their perceived quality of life. The use of therapy dogs (TD) has been widely researched as a source of non-pharmacological pain management. Studies have proven that a dog can reduce perceived pain in people with a variety of comorbidities. The purpose of this study was to prove that pain is modulated biologically by dogs and not just by human perception. Methods: This was …

Enjoyment, Motivation, And Self-Efficacy Towards Physical Activity Among Physical Therapy Students, Lauren Butler, Amanda Thomas, Teresa Munecas, Erasmo Alvarez, David Capote, Alexa Almonte, Madeline Dawson, Jordan Hale, Mikayla Kerekes, Kaitlyn Mitchell, Mark D. Rossi

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was to determine physical therapy (PT) students’ participation in and attitudes toward physical activity (PA).

Methods An electronic survey assessed demographic, academic, and sports history. Student’s PA level was assessed with the Godin Leisure-Time Exercise Questionnaire (Godin); PA enjoyment was assessed using the Physical Activity Enjoyment Scale (PACES); motivation was assessed using 4 items from the Modified Behavioral Regulation in Exercise (BREQ 3); and self-efficacy towards PA was assessed with the Exercise Self-Efficacy Scale (ESES). Descriptive statistics, Pearson correlations, and independent t-tests with 95% Confidence Interval (95% CI) were used.

Results In total, 228 …

Understanding The Relationship Between Occupation And Cognitive Abilities: A Preliminary Study, Deepak Puttanna, Srinidhi Konda, Mohammed Al Harbi

Internet Journal of Allied Health Sciences and Practice

Purpose: Understanding the cognitive abilities across various occupational backgrounds is deemed crucial, owing to the fact that the cognitive load imposed in each of the roles varies, thus there may be different levels of cognitive skills used in daily day-to-day activities. Also, it paves the way for the researchers to understand how an intellectually stimulating environment aids in better cognitive reserve or hinders cognitive decline. Method: A total of 60 participants aged between 30 to 50 years participated in the study. These participants were further divided into two broad groups, professional/technical workers and structural work occupations. These occupations were …

La Pensee Et Le Mouvant, Henri Bergson

Hannah Arendt Marginalia - All

Paris, Presses universitaires de France, 1950

Call #: B2430.B4 P36 1950

Contains marginalia, underlining and marginal lining.

PDF Information: 28 pages – 32.3mb

The Two Sources Of Morality And Religion, Henri Bergson

Hannah Arendt Marginalia - All

Garden City, N.Y. : Doubleday Anchor, 1935

Call #: B2430.B4 D42 1954

Contains marginalia, underlining, margin lining and endpaper notes.

PDF Information: 16 pages – 5.3mb

Duns Scotus: The Basic Principles Of His Philosophy, Efrem Bettoni

Hannah Arendt Marginalia - All

Washington, Catholic University of America Press, 1961

Call #: B765.D74 B43

Contains underling, marginal lining and endpaper notes

PDF Information: 27 pages – 12 MB