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Biochar Derived From Different Sources Ameliorates The Phytochemical And Physiological Characteristics Of Foxtail Millet (Setaria Italica) Under Water Stress, Mohammad Keshavarz, Ehsan Bijanzadeh, Hamid Reza Boostani

Turkish Journal of Botany

Organic material, such as biochar, can improve soil fertility and crop yield under water stress. A pot experiment was conducted to consider the effects of biochar on the pigment content, enzyme activity, physiological characteristics, and nutrient uptake of foxtail millet under water stress. Plants were tested under normal, mild, and severe irrigation regimes (100%, 75%, and 50% field capacity, respectively) using different biochar sources (licorice root biochar (LRB), cow manure biochar (CMB), cotton residue biochar (CRB), and municipal waste biochar (MWB)) and a control without fertilizer. Under severe water stress, the chlorophyll a content and total chlorophyll increased by 137.3% …

Enhancing Community Health Workers' Knowledge On Childhood Tuberculosis Screening In Nigeria, Rashidat A. Jolaoluwa

Biennial Convention (CONV)

Tuberculosis (TB) poses a significant global health challenge, especially in developing countries like Nigeria, where it disproportionately affects children. This Doctor of Nursing Practice (DNP) study seeks to enhance the knowledge of Community Health Workers (CHWs) and Community Health Extension Worker Students (CHEWs) in screening for childhood TB. Given the urgent need for early detection and intervention, the research focused on equipping CHWs and CHEWs with targeted educational resources. A pretest/posttest design was employed to evaluate changes in knowledge related to childhood TB screening among the participants. Statistical data analysis was conducted to assess improvements and ensure the reliability of …

Accelerating The Degradation Of Biodegradable Mulch Films In Soil And Compost Environments, Harshal Jayesh Kansara

Theses

The incomplete degradation of biodegradable mulch films (BMFs) in agricultural soils poses environmental challenges, with persistent plastic residues impacting soil health. This dissertation investigates the use of bioaugmentation with P. guariconensis to enhance BMF degradation under laboratory, raised bed, and field conditions. The research focuses on optimizing microbial delivery methods, evaluating the efficacy of drip and spray bioaugmentation techniques, and assessing mass loss as a primary metric for degradation. Laboratory experiments established proof-of-concept by demonstrating enhanced carbon mineralization, weight loss, and fragmentation of BMFs under bioaugmented conditions. These findings were translated to field-scale trials, where bioaugmentation treatments consistently outperformed untreated …

Flash Effect Is Diminished By Daily Fractionation Of Electron Rt In Mouse Skin, Aleksandra Ilina, William S. Thomas, Xu Cao, Matthew S. Reed, Kendall Jarvis, Albert Van Der Kogel, Nathaniel Van Asselt, Wesley S. Culberson, Brian W. Pogue

Dartmouth Scholarship

Objective. While FLASH radiotherapy is known to reduce skin damage in vivo from ultra-high dose rate (UHDR) irradiation relative to conventional dose rates (CDR), it is not clear whether this sparing is preserved when delivered as fractionated. This study was designed to directly assess whether three daily fractions would maintain the sparing effects in murine leg models and preserve the murine skin sparing with single fraction treatments. Approach. C57Bl/6j female mice were irradiated with 9 MeV UHDR and CDR beams from a FLASH-capable Mobetron system, in a dose escalation study with doses ranging from single dose 22–30 Gy in a …

Multimodal Cardiac Imaging Of Immune-Mediated Complications Post Heart Transplantation: A Contemporary Review, Bruno Bezerra Lima, Tam T Doan, Atilla Feher, James C Wilkinson, Marvin W Kronenberg, Chloe Carr, Malek Nayfeh, Tania Ruiz, Luke L Laws, Melissa Lou Silva, John A Wells, Leandro Slipczuk, Emily T Lippincott, John J Carr, Kaushik Amancherla, Cameron Henry, David Parra, Kelly Schlendorf, Quinn S Wells, Sean G Hughes, Jonathan Soslow

Faculty, Staff and Students Publications

Heart transplantation significantly enhances survival and quality of life for patients with end-stage heart failure. Despite advances in surgical and postoperative care, immune-mediated complications, acute graft rejection and cardiac allograft vasculopathy (CAV), remain major barriers to long-term success. Acute rejection predominantly affects early posttransplant survival, whereas CAV becomes a leading cause of mortality in later years. The gold standards for diagnosis, endomyocardial biopsy for rejection and coronary angiography for CAV, are invasive and imperfect. Noninvasive multimodality imaging is increasingly used to complement or, in selected scenarios, defer invasive testing. Echocardiography with strain detects early myocardial dysfunction when ejection fraction is …

Investigating The Neuronal Role Of The Proteasomal Atpase Subunit Gene Psmc5 In Neurodevelopmental Proteasomopathies, Sébastien Küry, Janelle E Stanton, Geeske M Van Woerden, Amélie Bosc-Rosati, Tzung-Chien Hsieh, Lise Bray, Marielle Oloudé, Cory Rosenfelt, Marie Pier Scott-Boyer, Victoria Most, Tianyun Wang, Jonas J Papendorf, Charlotte De Konink, Wallid Deb, Virginie Vignard, Maja Studencka-Turski, Thomas Besnard, Anna M Hajdukowicz, Franziska G Thiel, Sophie Wolfgramm, Laëtitia Florenceau, Silvestre Cuinat, Sylvain Marsac, Yann Verrès, Audrey Dangoumau, Léa Poirier, Ingrid M Wentzensen, Annabelle Tuttle, Cara Forster, Johanna Striesow, Richard Golnik, Damara Ortiz, Laura Jenkins, Jill A Rosenfeld, Alban Ziegler, Clara Houdayer, Dominique Bonneau, Erin Torti, Amber Begtrup, Kristin G Monaghan, Sureni V Mullegama, Catharina M L Nienke Volker-Touw, Koen L I Van Gassen, Renske Oegema, Mirjam S De Pagter, Katharina Steindl, Anita Rauch, Ivan Ivanovski, Kimberly Mcdonald, Emily Boothe, Andrew Dauber, Janice Baker, Noelle Andrea V Fabie, Raphael A Bernier, Tychele N Turner, Siddharth Srivastava, Kira A Dies, Lindsay C Swanson, Carrie Costin, Alali Abdulrazak, Rebekah K Jobling, John Pappas, Rachel Rabin, Dmitriy Niyazov, Anne Chun-Hui Tsai, Karen Kovak, David B Beck, May Christine V Malicdan, David R Adams, Lynne Wolfe, Rebecca D Ganetzky, Colleen C Muraresku, Davit Babikyan, Zdeněk Sedláček, Miroslava Hančárová, Andrew T Timberlake, Hind Al Saif, Berkley Nestler, Kayla King, M J Hajianpour, Gregory Costain, D'Arcy Prendergast, Chumei Li, David Geneviève, Antonio Vitobello, Arthur Sorlin, Christophe Philippe, Tamar Harel, Ori Toker, Ataf Sabir, Derek Lim, Mark J Hamilton, Lisa J Bryson, Elaine Cleary, Sacha Weber, Trevor L Hoffman, Anna M Cueto-González, Eduardo F Tizzano, David Gómez-Andrés, Marta Codina-Solà, Athina Ververi, Efterpi Pavlidou, Alexandros Lambropoulos, Kyriakos Garganis, Marlène Rio, Jonathan Levy, Sarah J Langas, Anne M Mcrae, Mathieu K Lessard, Maria Daniela D'Agostino, Isabelle De Bie, Meret Wegler, Rami Abou Jamra, Susanne B Kamphausen, Viktoria Bothe, Lorraine Potocki, Eric Olinger, Yves Sznajer, Elsa Wiame, Michelle L Thompson, Molly C Schroeder, Catherine Gooch, Raphael A Smith, Arti Pandya, Larissa M Busch, Uwe Völker, Elke Hammer, Kristian Wende, Benjamin Cogné, Bertrand Isidor, Jens Meiler, Clémentine Ripoll, Stéphanie Bigou, Frédéric Laumonnier, Peter W Hildebrand, Evan E Eichler, Kirsty Mcwalter, Peter M Krawitz, Florence Roux-Dalvai, Ype Elgersma, Julien Marcoux, Marie-Pierre Bousquet, Arnaud Droit, Jeremie Poschmann, Andreas M Grabrucker, Francois V Bolduc, Stéphane Bézieau, Frédéric Ebstein, Elke Krüger

Faculty, Staff and Students Publications

Neurodevelopmental proteasomopathies are a group of disorders caused by variants in proteasome subunit genes, that disrupt protein homeostasis and brain development through poorly characterized mechanisms. Here, we report 26 distinct variants in PSMC5, encoding the AAA⁺ ATPase subunit PSMC5/RPT6, in individuals with syndromic neurodevelopmental conditions. Combining genetic, multi-omics and biochemical approaches across cellular models and Drosophila, we unveil the essential role of proteasomes in sustaining key cellular processes. Loss of PSMC5/RPT6 function impairs proteasome activity, leading to protein aggregation, disruption of mitochondrial homeostasis, and dysregulation of lipid metabolism and immune signaling. It also compromises synaptic balance, neuritogenesis, and neural progenitor …

Transcription-Replication Collisions Trigger High-Fidelity Replication Reset, Matthew B Cooke, Kobie T Welch, Laura Deus Ramirez, Katelin M Hagstrom, Alice X Wen, Jennifer A Halliday, Susan M Rosenberg, Christophe Herman

Faculty, Staff and Students Publications

Double-stranded DNA ends arise from external agents or cellular processes like transcription-replication collisions (TRCs), threatening genome stability. Here, we performed genomic CRISPRi screens to uncover DNA end formation factors in Escherichia coli. We discovered that translation-transcription decoupling causes DNA end formation through a TRC-dependent pathway, which is lethal when DNA end processing by RecBCD is disrupted, but not when recombination is disrupted. We find that TRCs cause replisome stalling followed by "rear-ending" from trailing replisomes which generates free DNA ends, rather than strand breaks. Surprisingly, these DNA ends are resolved through a process we call "replication reset", where the stalled …

Dna Extrusion Size Determines Pathway Choice During Cag Repeat Expansion, Mayuri Bhatia, Ashutosh S. Phadte, Anna Lakhina, Anthony R. Monte Carloi Iii, Sarah Barndt, Anna Pluciennik

Department of Biochemistry and Molecular Biology Faculty Papers

DNA triplet repeat expansion causes several primarly neurological disorders like Huntington's disease, myotonic dystrophy type 1, and fragile-X related disorders. There is general consensus that recognition of extrahelical extrusions or hairpin-loop structures (formed by strand slippage) by the DNA mismatch repair protein MutSβ leads to repeat expansion by a mutagenic process. By contrast, the FAN1 nuclease attenuates triplet repeat expansion, the molecular basis of which was explained by our recent finding that FAN1 nuclease cleaves and initiates removal of extrahelical extrusions. Here we show that extrusions containing two or more triplet repeats are subject to recognition and processing by either …

Cover And Conents

Turkish Journal of Botany

No abstract provided.

Comparative Cytogenetics Study Via Fluorescent Chromosome Banding Of Three Solanum L. Species, Mona Abd Elgawad, Rim Hamdy, Ibrahim El Garf, Amany Sallam Abdo

Turkish Journal of Botany

Solanum L. subg. Solanum sect. Solanum has a wide distribution in Egypt with multiple overlapping morphological features, rendering the taxonomy of the Solanum nigrum complex difficult at the species level. This study focused on the S. nigrum complex, which consists of S. nigrum L., S. sinaicum Boiss., and S. villosum Mill. Cytogenetic characterization can provide additional taxonomic data and can be used to evaluate genetic diversity at the species level. We performed karyotype analysis of 3 Egyptian species for the first time by studying fluorescence banding patterns via 4’6-diamidino-2-phenylindole (DAPI) and chromomycin A3 (CMA). The three species vary noticeably in …

Prior Incarceration And Dental Insurance Trajectories Throughout Older Adulthood, A Testa, L Mijares, D B Jackson, V Maroufy, R Samper-Ternent, A C Neumann, R Mungia, K T Ganson, J M Nagata, T Oates

Faculty, Staff and Student Publications

Objectives: This study examines the relationship between prior incarceration and dental insurance trajectories throughout older adulthood.

Methods: A nationally representative sample of adults aged 55 y and older who participated in the 2012-2020 Health and Retirement Survey was analyzed (n = 6,383). Group-based trajectory modeling was used to identify distinct patterns of dental insurance coverage across the 8 survey waves. Multinomial logistic regression was used to assess the association between prior incarceration and dental insurance trajectory group membership.

Results: Four dental insurance trajectories were identified: persistent dental insurance (30.0%), intermittent high insurance (16.4%), intermittent low insurance (20.4%), and no …

Predicting The Response Of Triple Negative Breast Cancer To Neoadjuvant Systemic Therapy Via Biology-Based Modeling And Habitat Analysis, Casey E Stowers, Chengyue Wu, Clinton Yam, Jingfei Ma, Gaiane M Rauch, Thomas E Yankeelov

Faculty, Staff and Student Publications

Despite being the standard-of-care treatment, neoadjuvant therapy (NAT) attains a complete response only in approximately half of the patients with triple negative breast cancer. Thus, methods to predict and optimize patient response to NAT are needed. Previously, we employed patient-specific MRI data to calibrate a biology-based mathematical model that describes cell movement, proliferation, and death due to drug at the tumor level and cell proliferation at an image voxel level. We now extend our approach by using MRI data to group voxels into "habitats" whereby tumor cells of a habitat share the same proliferation. With this approach, we now calibrate …

Loss Of Idh1 And Idh2 Mutations During The Evolution Of Metastatic Chondrosarcoma, William Cross, Iben Lyskjær, Christopher Davies, Abigail Bunkum, Ana Maia Rocha, Tom Lesluyes, Fernanda Amary, Roberto Tirabosco, Cristina Naceur-Lombardelli, Mariam Jamal-Hanjani, Charles Swanton, Nischalan Pillay, Simone Zaccaria, Adrienne M Flanagan, Peter Van Loo

Faculty, Staff and Student Publications

Driver mutations in IDH1 and IDH2 are initiating events in the evolution of chondrosarcoma and several other cancer types. Here, we present evidence that mutant IDH1 is recurrently lost in metastatic central chondrosarcoma. This may reflect either relaxed positive selection for the mutant IDH1 locus, or negative selection for the hypermethylation phenotype later in tumor evolution. This finding highlights the challenge for therapeutic intervention by mutant IDH1 inhibitors in chondrosarcoma.

Maternal Obesogenic Diet Exposure Regulates The Offspring Gut Liver Axis And Fibroinflammatory Liver Disease, Naresh Naik Ramavath, Oğuz Özler, Holly Hinrichs, Francisco R Victorino, Vung Lian, Monica Young, Tarin M Bigley, Michael D Thompson

2020-Current year OA Pubs

Maternal obesogenic diet exposure (MODE) promotes fibroinflammatory liver disease in offspring via vertical transfer of an altered microbiome. The mechanism for how an altered offspring microbiome increases susceptibility to liver disease is not clear. A critical early life event termed the 'weaning reaction' is dependent on the early microbiome and when altered, results in worse pathologic inflammation. MODE attenuates the weaning reaction promoting worse liver disease in mice in an early microbiome-dependent manner. Using our MODE model and cross-fostering approaches we assessed the effect of MODE on neonatal gut-liver axis development. MODE shifts the bile acid (BA) profile, expression of …

Electrical Spinal Imaging: A Noninvasive, High-Resolution Approach That Enables Electrophysiological Mapping Of The Human Spinal Cord, Giulio Gabrieli, Richard Somervail, André Mouraux, Massimo Leandri, Patrick Haggard, Gian Domenico Iannetti

Research Outputs: 2025-Present

The spinal cord is the key bridge between the brain and the body. However, scientific understanding of spinal cord function has historically been limited because noninvasive measures of its neural activity have proven exceptionally challenging. In this work, we describe an enhanced recording and analysis approach, Electrical Spinal Imaging (ESI), to obtain noninvasive, high-resolution images of the electrical activity of the human spinal cord. ESI is analytically simple, easy to implement, and data-driven: it does not involve template-based strategies prone to produce spurious signals. Using this approach, we provide a detailed description and physiological characterization of the spatiotemporal dynamics of …

Effects Of Rehabilitative Device On Parkinsonian Gait, Brooke N. Ray, Ksenia I. Ustinova, Joseph E. Langenderfer

International Journal of Exercise Science

International Journal of Exercise Science 18(7): 1422-1440, 2025. https://doi.org/10.70252/TGOI6101 Parkinson’s disease (PD) is second in occurrence among neurodegenerative disorders after Alzheimer’s disease and significantly impacts gait and mobility. This research tested the effect of the NewGait rehabilitative device in PD impaired individuals. Twenty individuals with PD participated in this study. Walking gait for three conditions were analyzed: Normal, wearing NewGait and Post-NewGait. Standard spatial and temporal analysis measures as well as nonlinear measures from recurrence quantification were compared to determine any effects of the device on walking gait. NewGait was perceived to be both comfortable to wear as well as …

Post-Translational Modifications Of Psd-95 In Glutamatergic Synapses, Sai Kanuru, Het T. Gor, Lauren Kohlsaat, Daniel Bichao Paiva Parada,, Xela Bui, Jary Delgado

Undergraduate Research and Engagement Symposium

PSD-95 is a pivotal postsynaptic scaffolding protein that regulates synaptic maturation, receptor localization, and signaling proteins, including mediating NMDA receptor clustering and function in synaptic plasticity. NMDA receptor-dependent LTD is dependent on multiple post-translational modifications. One of these modifications, phosphorylation of PSD-95, destabilizes the protein which can prompt the exit of associated AMPARs from postsynaptic spines. Our investigations highlight a potential factor in PSD-95 destabilization, isomerization of phospho-T19 by Pin1. We hypothesize that Pin1 mediated phosphorylation of PSD-95 may either protect or target PSD-95 for ubiquitination, playing a critical role in NMDAR-LTD.

Recent Advances In The Synthesis And Pharmacological Profiling Of Pyrazolo[1,5-A]Pyrimidine Derivatives, Wesam S. Shehab, Seham Abdel-Shafi, Mostafa I. Abdelglil, Sabry Shehata

Al-Farahidi Biomedical Journal

An important class of fused heterocyclic compounds, pyrazolo[1,5-a] pyrimidines have a variety of biological activities, such as anticancer, antimicrobial (antibacterial, antifungal, and antiviral), and enzyme-inhibitory effects. Additionally, it improves the body’s antioxidants and lowers the risk of diabetes. The synthesis and reactivity of distinct pyrazolopyrimidine derivatives using various cyclization and condensation techniques are the main topics of this study. To comprehend these compounds’ function in biological activity, their structural characteristics were thoroughly examined. The chemical pathways, reaction circumstances, and structural alterations that affect their pharmacological potential were highlighted. Pyrazolo[1,5-a] pyrimidines and their derivatives have potential uses in medicinal chemistry—particularly in …

Examining The Impact Of Decreased Snowpack On The Rare Frosted Elfin Butterfly’S Host Plant, Christopher Walsh

Biology Student Scholarship

In response to climate change, Earth’s increased global temperature has caused less snowfall and earlier snowmelt in spring. These changes can alter an organism’s phenology, or timing of life history events. Such shifts in phenology may lead to mismatches between interacting species, which are correlated with a decline in the populations of host plant specialists and at-risk species. The rare frosted elfin butterfly (Callophrys irus) is listed as impaired in 5 states, and critically imperiled in 14. These host plant specialists only lay eggs on small yellow wild indigo (Baptisia tinctoria) and wild lupine (Lupinus perennis). If neither plant emerges …

Faculty Senate Agenda December 1, 2025, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• 3:00 Call to Order
• Approval of Minutes - November 3, 2025
• 3:05 University Business
• 3:20 Faculty Senate Business
• 3:30 Information
• EPC Report - November 6, 2025
• 3:45 Report
• Honors Program Annual Report
• USUSA Annual Report
• Faculty Evaluation Committee
• Academic Freedom and Tenure
• 4:10 Old Business
• 4:15 New Business
• Faculty Forum
• Adjourn: 4:30 pm

Intersectional Life Course Inequalities In Cardiovascular Health In Post-Apartheid South Africa, Winfred A. Avogo

Faculty Publications – Sociology and Anthropology

Background Health inequalities research typically employs single measurement modalities, which limit our understanding of how historical structural violence affects different dimensions of health experience across intersectional social positions over the life course. Methods Using longitudinal data from South Africa’s National Income Dynamics Study (2008–2017), we employed dual measurement approaches and intersectional life course analysis to examine cardiovascular health trajectories among 36,814 individuals (92,702 person-years of observation). Random-effects logistic regression modeled measured hypertension, while zero-inflated Poisson regression examined self-reported CVD comorbidity across birth cohorts defined by differential apartheid exposure, testing race × gender interactions explicitly. Results Pronounced birth cohort gradients emerged …

The Influence Of Muskrats On The Biodiversity Of Wetlands, Emma Thornton

Biology Student Scholarship

Wetlands are one of the most productive ecosystems in the world and are home to various plant and animal species. The relationships between the species living in the wetlands keep the ecosystem functional as well as increasing biodiversity. Increased biodiversity of wetlands creates more resilient plant communities. Muskrats are ecosystem engineers, meaning that they alter their surroundings to change the quality and quantity of the available resources through behaviors related to their eating habits and their burrow construction. Muskrats are herbivores and consume large amounts of vegetation, which creates opportunities for more plant species by creating new ecological niches. In …

Metabolomic And Lipidomic Atlas Of Human Hair Across Its Length., Maria Van De Lavoir, Yuanye Chi, Ting Zeng, Rani Robeyns, Maria Del Mar Delgado Povedano, Leen Jacobs, Celine Gys, Hugo Neels, Shuzhao Li, Alexander L N Van Nuijs, Adrian Covaci

Faculty Research 2025

The stable structure and growth cycle of human hair enables the accumulation of both endogenous and exogenous compounds, making hair an ideal matrix for long-term profiling. However, its exact molecular composition, shaped by root-to-tip variations, remains poorly understood. Here, we present a metabolome and lipidome atlas of human hair originating from a healthy cohort. The Human Hair Atlas maps over 1200 unique molecular species and highlights compounds prone to significant longitudinal variations. Metabolite and lipid levels vary by up to 50% along the length of the hair, underscoring the importance of accounting for segmental differences. We categorized 122 molecules as …

Deep Learning Reveals How Cells Pull, Buckle, And Navigate Fibrous Environments, Abinash Padhi, Arka Daw, Atharva Agashe, Medha Sawhney, Maahi M Talukder, Mehran M H Pour, Mohammad Jafari, Guy M Genin, Farid Alisafaei, Sohan Kale, Anuj Karpatne, Amrinder S Nain

2020-Current year OA Pubs

Cells in tissues navigate fibrous environments fundamentally differently than they do on flat substrates, but the establishment of cell forces in physiological fibrous settings remains poorly understood. Although factors such as the stiffness of the extracellular matrix (ECM) are known to drive behaviors, including cell motility on flat nonfibrous substrates, the interplay between fiber architecture and stiffness in fibrous ECM is not known. Here, we find that in fibrous environments, the directionality of mechanical forces overrides ECM stiffness as the primary regulator of contractility in migrating cells. Using an approach combining phase microscopy with deep learning to map forces in …

Conulariids From The Late Serpukhovian (Late Mississippian) Carbonate Deposits Of Ne Europe, Andrey Vladimirovich Zhuravlev, Andrey Vladimirovich Erofeevsky, Yadviga Alfredovna Vevel

Turkish Journal of Earth Sciences

The Late Mississippian (late Serpukhovian) conulariids are described from the deep carbonate platform facies of the northern Cis-Urals. The fossil assemblage also includes brachiopods, foraminifers, ostracods, conodonts, Sphenothallus (?), crinoids, and rare bryozoan and fish remains. Conulariid remains are represented by isolated rods and articulated thecae of Paraconularia aff. subulata (Hall). A carbon isotope study suggests that the conulariids were low-level consumers, likely feeding on seston.

Morphological Variability And Systematics Of Ponto-Caspian Cladocerans Of The Genus Cercopagis Sars, 1897 (Branchiopoda: Onychopoda: Cercopagidae), Larisa F. Litvinchuk, Spartak N. Litvinchuk

Turkish Journal of Zoology

In recent decades, significant changes have occurred in the composition of zooplankton, especially in the Ponto-Caspian Basin. An important component of zooplankton in this region is cladocerans of the genus Cercopagis. However, the introduction of invasive species means that many species of this genus have probably become extinct. Because their disappearance molecular study of these organisms is no longer possible. Therefore, a comparative analysis of morphological variability has become more important. We studied the morphological variability of all 12 currently known species of the genus. Samples from the Caspian, Azov, Black, and Baltic Seas were analyzed. The number of species …

Assessing The Validity Of The Mental Health–Related Survey In Collegiate Student-Athletes, Lindsey Keenan, Zachary K. Winkelmann, Luis Torres, Yvette Ingram, Rachel Daltry

Department of Kinesiology Scholarship and Creative Works

Context

Mental health screenings are recommended during preparticipation physical examinations. The Mental Health–Related Survey (MHRS), a 9-item questionnaire adapted from the 18-item Mental Health Screening Form-III, is suggested in 3 consensus and/or position statements. However, there is no evidence on the effectiveness of the MHRS.

Objective

To assess the validity of the MHRS for mental health screening in collegiate student-athletes.

Design

Cross-sectional study.

Setting

University athletic program.

Patients or Other Participants

Five hundred fifteen National Collegiate Athletic Association Division II student-athletes (age = 20 ± 1 years).

Main Outcome Measure(s)

Participants completed the MHRS, the Patient Health Questionnaire for depression …

Justice Ketanji Brown Jackson Inspires Ole Miss Students During Stop, Staff Report

University of Mississippi News

OXFORD, Miss. – Drawing on stories from her memoir, U.S. Supreme Court Justice Ketanji Brown Jackson told University of Mississippi students on Sunday (Nov. 16) that perseverance and strong mentors helped guide her path to the bench.

Variation In Corneal Biomechanical Properties Following Continuous Cross-Linking Treatment, Daniela Oehring, Chenhao Zhao, Xinyu Yao, Yewei Zhao, Fangjun Bao, Ahmed Elsheikh, Hongjiang Wu, Jiahui Zon, Xuanya Tong, Lan Yang, Xiaofei Zhou, Ying Li, Yanjie Shen, Yufeng Ye, Shihao Chen, Jia Qu, Qinmei Wang

School of Health Professions

BackgroundThis retrospective study aimed to evaluate the ecacy of transepithelial accelerated corneal cross-linking when applied separately (transEpi ACXL) or combined with phototherapeutic keratectomy (transPTK ACXL) in keratoconic eyes using biomechanical parameters.MethodsThe study included eyes with progressive keratoconus treated with either continuous transEpi ACXL or transPTK ACXL with 6 months of follow-up. The following parameters were assessed preoperatively and 6 months postoperatively: biomechanically corrected intraocular pressure (bIOP), maximum and mean keratometry (Kmax and Km), minimum and central corneal thickness (MCT and CCT), corneal coma, best-corrected visual acuity (BCVA), deformation amplitude ratio at the apex and 2 mm nasal/temporal (DAR2), integrated inverse …

Single-Cell Transcriptomic Analysis Of Peripheral Blood Mononuclear Cells Reveals Key Immune Responses In St-Segment Elevation Myocardial Infarction, Zheng Zhang, Shengfang Wang, Yahui Liu, Gaohan Li, Qianqian Cheng, Wei Yang, Gan-Xin Yan, Chuanyu Gao

Department of Medicine Faculty Papers

BACKGROUND: Inflammation plays a crucial role in the pathogenesis of ST-segment elevation myocardial infarction (STEMI). However, the precise immunological mechanisms remain incompletely understood. Single-cell RNA sequencing (scRNA-seq) provides a powerful approach to dissect immune cell heterogeneity and dynamic changes at single-cell resolution.

METHODS: Peripheral blood mononuclear cells (PBMCs) were collected from 7 STEMI patients (within 6h after primary percutaneous coronary intervention) and 3 healthy controls. Single-cell suspensions were prepared and subjected to scRNA-seq using the 10x Genomics Chromium platform and Illumina NovaSeq 6000. Data were processed using Cell Ranger and analyzed with Seurat for quality control, clustering, and annotation. Differentially …