Digital Commons Network^™

Vaping Insights Perceptions And Experiences On A College Campus, Willard G. Jackson

Masters Theses and Doctoral Dissertations

The purpose of this study was to determine if relationships existed between student vaping habits in proximity to a college campus and current tobacco related bans implemented by the institution. Determining these relationships provided insights that can be utilized to maximize effectiveness of campus tobacco policy. Research outcomes represented a framework for educating current and potential tobacco consumers on campus regarding harm reduction, tobacco cessation, and resources available to prevent a lifetime of nicotine addiction or other tobacco related harm to health. The study addressed research questions in a mixed-methods design. Quantitative research questions included: Does a relationship exist between …

An Investigation Of Collateral Activity Effects On Behavior Maintained By A Drl 72‑Second Schedule, Cassidy M. Graham

Masters Theses

Impulsivity is a key behavioral trait with broad implications for clinical disorders such as Attention Deficit Hyperactivity Disorder ADHD, and substance use disorders SUD, where impaired inhibitory control contributes to maladaptive outcomes. In preclinical research, animal models provide valuable tools for examining behavioral processes associated with impulsivity. The Differential Reinforcement of Low Rates (DRL) schedule, offers a precise measure of response inhibition and timing by requiring subjects to withhold responses for reinforcement. This study employed DRL72s schedule to investigate impulsive action in male and female Sprague-Dawley rats, with an emphasis on sex-based differences and the potential influence of environmental factors. …

Bridging The Gap Between Network Science And Network Systems To Identify And Mitigate Cyber Risk: Identify And Mitigate Backdoor Attacks On Graph Neural Networks And On Complex Systems, Sabah Ettahri

Electrical & Computer Engineering Projects for D. Eng. Degree

This doctoral project aims to bridge the gap between graph theory and network science to identify and mitigate cyber risk, represented as a CY-Triangular Network that connects different networks. The CY-Triangular Framework is a cybersecurity system that integrates graph theory and network science through an interoperable learning approach. The objective of this project is to bridge the gap between two domains: network science and network systems. Accordingly, it examines one representative network from each field, focuses on a complex system network, and explores Graph Neural Networks (GNNs). The connection between these domains lies in graph theory. This research demonstrates that …

Disruption Of The Placenta–Brain Axis In Transgenic Mice Lacking Serotonin Transporter (Sert) In Trophoblast Cells, David T. Ellenberger, Zhen Lyu, Rosalind T. B. Herrington, Jessica A. Kinkade, Gustavo W. Leone, Ji Ying Sze, Nathan J. Bivens, R. Frank Baker, R. Michael Roberts, Trupti Joshi, Cheryl S. Rosenfeld

Biomedical Sciences

Serotonin reuptake inhibitors (SSRIs) are commonly prescribed to pregnant women experiencing depression. Such drugs, however, might adversely affect placenta and fetal brain development. Parietal trophoblast giant cells (pTGCs) in the mouse placenta are postulated to internalize maternal serotonin (5-HT) via transport through SERT, encoded by Slc6a4, and to provide the initial source of 5-HT to the emerging brain via the placental–brain axis. Genetic deletion of Slc6a4 in pTGCs has been hypothesized to impact placental and fetal brain development. A transgenic mouse line with high-affinity SERT, encoded by Slc6a4, was selectively deleted by pairing mice with Cre recombinase linked …

G2pdeep-V2: A Web-Based Deep-Learning Framework For Phenotype Prediction And Biomarker Discovery For All Organisms Using Multi-Omics Data, Shuai Zeng, Trinath Adusumilli, Sania Zafar Awan, Manish Sridhar Immadi, Dong Xu, Trupti Joshi

Biomedical Sciences

Multi-omics data offers rich insights into complex traits across organisms, yet integrating and analyzing these datasets for phenotype prediction and marker discovery remains challenging. Researchers need accessible tools that combine deep learning, hyperparameter optimization, visualization, and downstream analysis in a unified web platform. To address this, we developed G2PDeep-v2, a web-based platform powered by deep learning for phenotype prediction and marker discovery from multi-omics data across a wide range of organisms, including humans and plants. The server provides multiple services for researchers to create deep-learning models through an interactive interface and train these models using an automated hyperparameter tuning algorithm …

Flux Crystal Growth Of A Series Of Calcium Rare Earth Silicate Chlorides Calnsio4Cl (Ln = Pr, Nd, Sm, Eu, Gd, And Tb): Mixed Anion Materials With A Spodiosite-Type Structure, Maria Goncalves, Mark D. Smith, Hans Conrad Zur Loye

Faculty Publications

A series of calcium rare earth silicate chlorides, CaLnSiO4Cl (Ln = Pr, Nd, Sm, Eu, Gd, and Tb), was obtained as single crystals from flux crystal growth. The structures were determined by single crystal X-ray diffraction and were found to be related to the spodiosite/Wagnerite mineral structure, Ca2PO4F. The obtained compositions are variations of the spodiosite structure that result from two simultaneous elemental substitutions. Replacing one calcium for one rare earth element and the simultaneous replacement of one VO4³⁻ or PO4³⁻ with one SiO4⁴⁻. CaEuSiO4Cl was found to luminesce, and its photoluminescence spectrum is reported.

Water Circulation Beneath A Hovering Suas For Water Quality Monitoring Applications, Erin E. Hackett, Boone Fleenor, Jensine C. Coggin, Duvall Dickerson-Evans, Nikolaos Vitzilaios, Whitney E. Schuler, Paige K. Williams, Michael L. Myrick

Faculty Publications

Water quality has traditionally been measured via in situ sensors and satellites. The latter has limited applicability for smaller inland water bodies, while the former requires significant logistics, labor, and expense for routine sampling, and reactive/spurious sampling is often not feasible as a result (e.g., sampling pre-/post-storm). Consequently, small uncrewed aircraft system-based (sUAS-based) sampling has emerged as a potential solution to bridge these sampling gaps and challenges. But sampling from an sUAS is complicated by the need to pump water from depth, rather than suspending a sensor from the sUAS, due to concern over sampling sUAS-impacted waters. Here, we measure …

Thermodynamic Assessment Of The Li, Na, K, Cs | F, I Reciprocal Salt For Msr Applications, Clara M. Dixon, Mina Aziziha, Amir Mofrad, Jorge Paz Soldan Palma, Ronald E. Booth, Aiswarya Padinhare Manissery, Jack A. Wilson, Hans Conrad Zur Loye, Hunter B. Tisdale, Juliano Schorne-Pinto, Theodore M. Besmann

Faculty Publications

Gibbs energy models necessary to describe the thermochemical behavior of cesium and iodine in molten FLiNaK (46.5LiF-11.5NaF-42KF mol%), a proposed molten salt reactor coolant and fuel solvent, have been developed as they are of concern due to their high radiotoxicity and volatility. The six constituent pseudo-binary systems LiI-CsI, LiI-KI, LiI-NaI, NaI-KI, KI-CsI and NaI-CsI were evaluated using available phase equilibria and mixing enthalpy measurements. The models for the ternary reciprocal salt systems Li,Cs|F,I, Li,K|F,I, Li,Na|F,I, Na,K|F,I, Na,Cs|F,I and K,Cs|F,I were obtained by interpolation of the optimized pseudo-binary systems and parameters fit as necessary based on observed behavior. The additive (common …

2025-12-01 Caudill Connection, Morehead State University. Caudill College Of Arts, Humanities And Social Sciences.

Caudill Connection

Caudill Connection newsletter for December of 2025.

Let’S Talk Mental Health: An Assessment Of Oregon Agricultural Stakeholders Discussing Mental Health, Whitney Stone, Lauren Chase, Taylor Foerster

Journal of Human Sciences and Extension

Working in agriculture presents some unique mental health stressors, including financial difficulties, climate variability, and isolation. Currently, Extension offers mental health literacy programming addressing mental health and suicide in agricultural communities; however, some of the programming is underattended, and resources are underutilized. We sought to find out how communicating about mental health resources was perceived by agricultural stakeholders who work closely with farmers and ranchers, including agribusiness employees, leaders in the community, and pre-service agriculture teachers. Through this mixed-method study using focus groups and a survey, we wanted to find out the perceptions of mental health resources to help inform …

Rural Mental Health Challenges: Addressing Community-Specific Needs Of Rural Mississippians, Mary Marshall Waller, Mary Nelson Robertson, Holli H. Seitz, Michael R. Nadorff, David R. Buys

Journal of Human Sciences and Extension

America’s mental health crisis uniquely impacts rural areas. Challenges surrounding intention and accessibility to engage in mental health-fostering behaviors exacerbate disparities in rural mental healthcare. In this study, Cooperative Extension personnel assess rural Mississippians’ intention to engage in mental health-fostering behaviors, accessibility to mental health-fostering behaviors, and helpfulness of increased access to resources for mental health challenges to determine if relationships exist between these variables. Rural Mississippi adults were recruited via an online survey panel to complete a 147-item web-based questionnaire (n = 274). Findings suggest rural adults’ intention to engage in mental health-fostering behaviors favored connecting with family and …

Full Issue, Volume 13, Number 3, Donna J. Peterson Dr., Scott Cummings, Elizabeth Gregory North

Journal of Human Sciences and Extension

No abstract provided.

Burden Of Neurodevelopmental Disorders In Kenyan Children, Symon Kariuki, Patricia Kipkemoi, Martha Kombe, Mary Bitta, Jacqueline Phillips Owen, Amina Abubakar, Charles Newton

Institute for Human Development, East Africa

Importance: Neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD), attention-deficit/hyperactivity disorder (ADHD), and intellectual disability contribute to one-tenth of the global burden of mental and neurologic disorders. The burden of NDDs is not well documented in Africa.

Objective:To assess the prevalence, risk factors, and comorbidities of NDDs in young Kenyan children.

Design, setting and participants: This cross-sectional study was conducted among children aged 6 to 9 years residing in the Kilifi Health and Demographic Surveillance System in Kenya. In stage I of the study, children were screened for NDDs from March 16, 2015, to September 14, 2016; those …

Anxiety, Depression And Associated Medical Symptoms In Kenyan Hiv+ Women: Rural Vs. Urban Context, Laura L. Van Auker, Miriam Wagoro, Janet Meda, Mariana Javeza Omenda

Biennial Convention (CONV)

Background: Advances in HIV therapeutics for women living with HIV (WLWH) in sub-Saharan Africa have shifted focus from deadly AIDS to chronic disease management. This shift underscores the need for integrated mental health and HIV care in low-resource settings, particularly addressing medical comorbidities and antiretroviral (ARV) side effects that exacerbate anxiety and depression. Conditions such as anemia, diabetes, hypertension, and malaria, alongside ARV-related side effects like chronic pain, fatigue, and neuropathy, contribute to overlapping physical and mental health symptoms and challenges. Integrating mental health screening into primary care facilitates identifying primary and secondary symptom etiologies, optimizing outcomes. Urban and rural …

Construction And Validation Of A Colorectal Cancer Diagnostic Model Based On Ferroptosis-Related Genes, Juan Wang, Qiuyue Zhang

Saudi Medical Journal

ABSTRACT Objectives: To establish a ferroptosis-related colorectal cancer (CRC) diagnostic model by integrating machine learning and gene expression analysis. Tumorigenesis is strongly linked to ferroptosis, an iron-mediated kind of cell death. The dismal prognosis of CRC, a severely malignant gastrointestinal cancer, accentuates the demand for effective diagnostic biomarkers. Methods: The study was performed between January 2024 and 2025. The GEO database provided 2 openly searchable gene expression profiles (GSE9348 and GSE21510) from CRC as well as non-tumor tissues. Genes that were expressed differently in tumor and healthy tissues were found using the GSE9348 dataset. Distinct genetic biological functions were identified …

The Role Of Community Libraries In Repackaging Scientifically Researched Information For Rural Farming Communities: A Review, Jackline Estomihi Kiwelu, Patrick Ngulube

Libraries

Objective

Scientifically researched information is often found in journal articles, book chapters, and conference papers, which can be technical and challenging for those without training. Repackaging information into a simpler and preferred language can make it easier for undereducated rural communities to access. This narrative review investigates the strategies community libraries can adopt to repackage scientifically researched information for easier access by rural farming communities. This study contributes to the literature gap on research-based information repackaging by community libraries for rural development.

Methods

The literature search for this narrative review was conducted across several databases, evidence Based Library and Information …

Functional Characterization Of The Hssb1 K94q Mutation, Isaiah Singleton

All Theses

Genome stability depends on precise DNA repair pathways such as homologous recombination (HR), where human single-stranded DNA-binding protein 1 (hSSB1) stabilizes single-stranded DNA (ssDNA) intermediates and recruits repair complexes. Post-translational modifications, including acetylation, are known to regulate hSSB1 activity, but their molecular effects remain poorly defined. This study examined the role of lysine 94 (K94) acetylation using a glutamine substitution mutant (K94Q) that mimics the acetylated state. Recombinant hSSB1 wild type (WT) and hSSB1_K94Q were expressed in Escherichia coli and purified using Ni–NTA affinity chromatography. Biochemical analyses, including electrophoretic mobility shift assays (EMSA), single-strand annealing assays, and displacement loop …

Comparison Of The Recent Icrp Occupational Intakes Of Rradionuclides Series To Annual Limits On Intake (Ali) In The United States For Select Radionuclides, Aidan B. Barker

All Theses

Dose coefficients (DCs) and secondary limit values (such as the annual limit on intake [ALI] and derived air concentration [DAC]) are useful and convenient quantities in radiation protection (RP) for estimation of radiological dose and the practical application of dose limits. DCs link radioactivity intake to dose while secondary limit values express a dose limit in terms of the type and extent of exposure. The International Commission on Radiological Protection (ICRP), an international organization which provides guidance and recommendations for RP, calculates, tabulates, and updates DCs following new findings and updated knowledge relevant to dose determination (e.g. improved human biokinetics, …

Optimizing Endothelial Cell Specific Polymersome-Based Atheroprotective Therapies, Ally C. Brawner

All Theses

Atherosclerotic cardiovascular disease is the number one cause of death in the United States and the world. Every year, billions of dollars are spent in the US alone for direct treatments of this disease, especially on prescription medicines like statins. However, these medications have been unable to curtail global mortality rates, partially because they do not target the entirety of atherosclerotic pathophysiology. A key area of this pathophysiology is that atheroprone arteries typically include pro-inflammatory endothelial cells that exhibit decreased levels of apoAI-mediated cholesterol efflux and an increased release of adhesion molecules, such as VCAM-1. The objective of my project …

The Psychological Impacts Of Higher Education Educators During The Covid-19 Pandemic, Ashlee Morgan Kemp

Dissertations

The purpose of this study was to examine the impact of the COVID-19 pandemic on the psychological well-being of higher education educators—specifically stress, anxiety, depression, alienation, and burnout—and to identify the coping strategies they employed while adapting to emergency hybrid instruction. This study was guided by the following research questions: What were the primary psychological impacts on higher education instructors’ well-being during the COVID-19 pandemic? How did the pandemic influence instructors’ experiences of stress, anxiety, depression, alienation, and burnout? Additionally, in what ways did educators cope with the instructional and professional challenges that emerged during this period? Guided by a …

Lgbtq+ Adolescents With Disabilities’ Experiences Of School Connectedness And Identity Navigation, Lyndsay Loretta Mccabe

Dissertations

In the United States, LGBTQ+ students have recently faced a barrage of school-based anti-LGBTQ+ legislation and policies (American Civil Liberties Union, 2025). Little is known about the effects of such policies and the overall sociopolitical climate on school connectedness and identity navigation for LGBTQ+ adolescents with disabilities. School connectedness, or the degree to which students feel that they belong at their school, is associated with numerous academic, behavioral, and social-emotional benefits (K. Allen et al., 2018; Centers for Disease Control and Prevention [CDC], 2022b). Students who are at the intersection of multiple marginalized identities, such as LGBTQ+ adolescents with disabilities, …

Effects Of Exercise Timing On Circadian Rhythm And Functional Outcomes In Cancer Patients Undergoing Treatment, Buck Williams Covington Ii

Dissertations

Poor sleep quality and circadian rhythm disruption are commonly reported among cancer survivors and may contribute to worsened health outcomes, including increased fatigue, psychological distress, and reduced quality of life. While some recent studies suggest that exercise can improve sleep and circadian regulation in cancer survivors, limited research exists on how the timing of this exercise affects these outcomes in cancer survivors. The purpose of this study was to examine the effects of a 12-week supervised exercise intervention, performed either in the morning (AX) or evening (PX), on functional capacity, subjective and objective sleep quality, and peripheral markers of circadian …

Stayin’ Alive: Examining The Moderating Effect Of Suicide Resilience On The Relationship Between Sexual Minority Stress And Subjective Well-Being, Natalie A. Sachs

Dissertations

Suicidality among sexual minorities is concerning and results from increased social stress, societal stigma, and experiences of discrimination. The effects of sexual minority stress (SMS) lead to negative outcomes for sexual minority college students. The purpose of the current study was to better understand the role of suicide resilience in moderating the adverse effects of SMS among sexual minority college students. The following research questions and hypotheses guided this study: Q1 Does SMS have any effect on subjective well-being among college-student sexual minority individuals (SMIs)? Q2 Does SMS have any effect on suicide resilience among college student SMIs? Q3 To …

Evaluating The Effectiveness Of An Air Purification System In Reducing Bacterial Chondronecrosis With Osteomyelitis Lameness In Broiler Chickens, Abdulaziz Ali Alqahtani

Graduate Theses and Dissertations

Bacterial chondronecrosis with osteomyelitis (BCO) is the primary cause of lameness in commercial broiler production and has a profound impact on animal welfare and cost-effectiveness. The purpose of this experiment was to examine the effect of an air purification system on mitigating BCO lameness in broiler chickens. One thousand eight hundred broiler chicks were reared in two side-by-side research barns. Eight air filtration units were installed in one building, and none in the other. Treatment groups in both houses included positive control birds on wire flooring to induce BCO, as well as negative control, feed additive, vaccination, and a combination …

Advancement Of Wearable Hardware & Possible Cross-Sector Applications, Yassine Chahid, Patrick Slattery

Publications and Research

This study examines recent advances in wearable technologies including smart glasses, watches, rings, and related devices. It evaluates their applications across healthcare, manufacturing, education, and logistics. As real-time data collection, hands-free interaction, and continuous health monitoring become more prevalent, wearables are emerging as pivotal tools for both personal and professional contexts. The methodology combines a comparative analysis of current-generation devices, a review of technical specifications from manufacturer documentation, and case studies of specialized deployments, particularly in medical diagnostics, remote monitoring, and workplace efficiency. Project findings will indicate the rate at which wearable devices are moving beyond consumer fitness tracking and …

Advancing Effective Connectivity Analysis: Robust And Sparse Group Dynamic Causal Modeling Via Extended Parametric Empirical Bayes, Godfred Arhin

Open Access Theses & Dissertations

Dynamic Causal Modeling (DCM) provides a principled framework for estimating effective connectivity in neuroimaging data, with Parametric Empirical Bayes (PEB) enabling hierarchical inference across sessions and subjects. However, standard PEB assumes Gaussian distributions at all hierarchical levels and employs conventional shrinkage priors that do not enforce true sparsity, limiting robustness to outlying subjects and reducing sensitivity to parsimonious connectivity structures. This thesis introduces a robust, sparsity-inducing hierarchical extension to DCM-PEB that addresses these limitations through two key innovations. First, a Student-t group-level likelihood replaces the conventional Gaussian likelihood, automatically downweighting outlying subject-level parameters using adaptive precision weights while retaining computational …

Gpu-Based Electromagnetic Microwave Tomography For Brain Imaging And Stroke Detection, Pablo Sotelo Torres

Open Access Theses & Dissertations

Each year, an estimated 795,000 people in the U.S. suffer a stroke, with approximately 610,000 being first-time cases. Of these, 87% are ischemic strokes, while the remaining 13% are hemorrhagic. Current imaging methods, such as Computed Tomography (CT), Positron Emission Tomography (PET), and Magnetic Resonance Imaging (MRI), provide useful information into brain tissue properties; while each technique has its advantages, they remain expensive, non-portable, and often too slow for emergency bedside or in-ambulance use. Electromagnetic Microwave Tomography (EMT) offers a promising alternative: an affordable, portable, rapid, and safe method for stroke detection. By contrasting dielectric properties between healthy and affected …

Antioxidant Enzymes And Osmolyte Accumulation In Okra Cultivars Under Drought Stress, Jawad Ali, Ibadullah Jan, Hidayat Ullah, Muhammad Adnan, Shah Fahad, Hassan Alsberi, Khulud Albalawi, Hakki Akdeniz, Manzoor Ahmmad, Beena Saeed, Noor Us Sabah, Mian Sayed Khan, Abdul Basir, Muhammad Romman, Ayman El Sabagh

The Philippine Agricultural Scientist

Drought stress brought about by worsening environmental conditions due to climate change has increasingly damaging effects on crop production systems. To mitigate these effects, several physiological and biochemical aspects of plants could be used as markers in breeding for the selection of drought-resistant cultivars. Therefore, this study aimed to evaluate the performance of 8 okra cultivars (Arka Anamika, Punjab Selection, Posaswami, Tulsi, Subz Pari, Super Green, Local Multani, and Green Star) under well-watered (control), mild drought stress, and severe drought stress conditions by irrigating plants at an interval of 3, 6, and 9 d after 30 d of planting. Results …

Gastropod Assemblage And Biofilm Abundance On Rocky Shores Of Southern Antique, Panay, Philippines, Mia Jane D. Geneblaza, Karen A. Villarta-Lane

The Philippine Agricultural Scientist

The gastropod assemblage and biofilm abundance, measured as chlorophyll a levels, were examined at 3 rocky shore sites in southern Antique, Panay, Philippines, in February 2024 to address significant gaps in current knowledge and help better understand the ecological dynamics of rocky intertidal zones. A total of 14 families comprising 22 genera and 31 species were identified from the area. The family Littorinidae was the most speciesrich, comprising 9 species. Among these, the scabra periwinkle Littoraria scabra (Philippi 1846) was the most abundant, comprising on average 50.17% of the total abundance across sites. Other identified gastropod families included Muricidae (5 …

Comparative Effects Of Organic-Based Seed Treatments On Seed Viability And Vigor Of Rice (Oryza Sativa L.) Varieties, Cielo Luz C. Mondejar

The Philippine Agricultural Scientist

Access to high-quality rice seeds remains limited for small and marginal farmers due to high costs, while traditional rice varieties favored by many farmers often suffer from poor seed viability. Seed treatment presents a practical and low-cost approach to enhance seed performance. This study conducted 2 independent experiments to evaluate the effectiveness of 3 organic-based seed treatments: vermitea, a Trichoderma solution, and a water hyacinth decoction. In the first experiment, seeds from 4 traditional rice varieties (Redrice, Dinorado, Calatrava, and Arabon) were treated with distilled water (control) and 75% dilute solutions of each treatment. The second experiment involved different seed …