Digital Commons Network^™

Phylogenetic Relationships Of Genera In The Caddisfly Family Limnephilidae Using Anchored Hybrid Enrichment-Based Phylogenomic Analysis (Insecta:Trichoptera), Kyle Charles Rawlinson

Theses and Dissertations

Limnephilidae is a large family within Trichoptera, consisting of 4 subfamilies (Dicosmoecinae, Ecclisomyiinae, Limnephilinae, and Philocascinae), 98 genera, and 1178 species. It is among the most diverse families within Trichoptera. It is also ecologically diverse, occupying more habitats than any other family in the order. There are currently no published generic phylogenies of Limnephilidae based on molecular data. Here we used anchored hybrid enrichment to capture and sequence 922 loci for 57 species taken from what have been considered the full range of genera in the family. We expanded the taxon sampling by adding supplementary species with DNA barcodes, 28S …

Edtech Culturation: Integrating A Culturally Relevant Pedagogy Into Educational Technology, Jenny Eppard, Amir Kaviani, Michael Bowles, Jason Johnson

All Works

In recent years, the use of technology in educational contexts including e-learning has become increasing ubiquitous. While it is commonly believed that technology use can facilitate the process of teaching and learning, it is of paramount importance to adopt a Culturally Relevant Pedagogy (CRP) to address the needs of students who might experience difficulty because of cultural, linguistic and technological obstacles that might be inherent in the use of educational technology. With this consideration in mind, the present paper reports on the findings of a qualitative research involving three case studies based on structured interviews with three university professors who …

Enhancing Cancer Care Of Rural Dwellers Through Telehealth And Engagement (Encore): Protocol To Evaluate Effectiveness Of A Multi-Level Telehealth-Based Intervention To Improve Rural Cancer Care Delivery, Tuya Pal, Pamela C. Hull, Tatsuki Koyama, Phillip Lammers, Denise Martinez, Jacob Mcarthy, Emma Schremp, Ann Tezak, Anne Washburn, Jennifer G. Whisenant, Debra L. Friedman

Markey Cancer Center Faculty Publications

BACKGROUND: Despite lower cancer incidence rates, cancer mortality is higher among rural compared to urban dwellers. Patient, provider, and institutional level factors contribute to these disparities. The overarching objective of this study is to leverage the multidisciplinary, multispecialty oncology team from an academic cancer center in order to provide comprehensive cancer care at both the patient and provider levels in rural healthcare centers. Our specific aims are to: 1) evaluate the clinical effectiveness of a multi-level telehealth-based intervention consisting of provider access to molecular tumor board expertise along with patient access to a supportive care intervention to improve cancer care …

High-Fructose, High-Fat Diet Alters Muscle Composition And Fuel Utilization In A Juvenile Iberian Pig Model Of Non-Alcoholic Fatty Liver Disease, Heather C Spooner, Stefani A Derrick, Magdalena Maj, Rodrigo Manjarín, Gabriella V Hernandez, Deepali S Tailor, Parisa S Bastani, Rob K Fanter, Marta L Fiorotto, Douglas G Burrin, Michael R La Frano, Angelos K Sikalidis, Jason M Blank

Children’s Nutrition Research Center Staff Publications

Non-alcoholic fatty liver disease (NAFLD) is a serious metabolic condition affecting millions of people worldwide. A “Western-style diet” has been shown to induce pediatric NAFLD with the potential disruption of skeletal muscle composition and metabolism. To determine the in vivo effect of a “Western-style diet” on pediatric skeletal muscle fiber type and fuel utilization, 28 juvenile Iberian pigs were fed either a control diet (CON) or a high-fructose, high-fat diet (HFF), with or without probiotic supplementation, for 10 weeks. The HFF diets increased the total triacylglycerol content of muscle tissue but decreased intramyocellular lipid (IMCL) content and the number of …

Aberrant Crosstalk Between Insulin Signaling And Mtor In Young Down Syndrome Individuals Revealed By Neuronal-Derived Extracellular Vesicles, Marzia Perluigi, Anna Picca, Elita Montanari, Riccardo Calvani, Federico Marini, Roberto Matassa, Antonella Tramutola, Alberto Villani, Giuseppe Familiari, Fabio Di Domenico, D. Allan Butterfield, Kenneth J. Oh, Emanuele Marzetti, Diletta Valentini, Eugenio Barone

Chemistry Faculty Publications

INTRODUCTION: Intellectual disability, accelerated aging, and early-onset Alzheimer-like neurodegeneration are key brain pathological features of Down syndrome (DS). Although growing research aims at the identification of molecular pathways underlying the aging trajectory of DS population, data on infants and adolescents with DS are missing.

METHODS: Neuronal-derived extracellular vesicles (nEVs) were isolated form healthy donors (HDs, n = 17) and DS children (n = 18) from 2 to 17 years of age and nEV content was interrogated for markers of insulin/mTOR pathways.

RESULTS: nEVs isolated from DS children were characterized by a significant increase in pIRS1^Ser636, a marker of …

To Engage Or Disengage: The Impact Of Coping Strategies, Sex, And Stress History On Cortisol Reactivity Among Urban Adolescents, Madeline Curzon

College of Science and Health Theses and Dissertations

Stress affects people daily and can prove maladaptive to mental health if chronic or acute. Effective coping responses may mitigate the negative effects of intense or prolonged stress through physiological processes such as HPA axis activity. Previous research has found one specific coping dimension, engagement/disengagement, to be predictive of cortisol reactivity in response to lab-induced stressors. Sex and stress history also contribute to the relationship between coping and cortisol reactivity. However, these processes are not as well understood in adolescent populations and have not been explored across different types of stressors. The present study explored the relationship between coping and …

The Effects Of Triaminopyrimidine Analogs And Gold(I) Chloride Compounds On Cell Proliferation And Apoptosis In Mda-Mb-231 Human Breast Cancer Cells, Robin Redline

College of Science and Health Theses and Dissertations

Breast cancer is a common disease that affects both women and men all over the world. Triple negative breast cancer is an aggressive subtype of breast cancer with poor survival statistics and few available treatment options. Uncontrolled cell proliferation and the ability to avoid programmed cell death, apoptosis, are two shared hallmarks of cancers. Previous research has shown a group of heterocyclic molecules called triaminopyrimidines, not tested in this study, may be effective antiproliferative agents. Previous research has also shown that some gold(I) complexes not tested in this study, may be promising anticancer agents. In this study, a few chemicals …

Identification Of Disease-Linked Hyperactivating Mutations In Ube3a Through Large-Scale Functional Variant Analysis, Kellan P Weston, Xiaoyi Gao, Jinghan Zhao, Kwang-Soo Kim, Susan E Maloney, Jill Gotoff, Sumit Parikh, Yen-Chen Leu, Kuen-Phon Wu, Marwan Shinawi, Joshua P Steimel, Joseph S Harrison, Jason J Yi

Open Access Publications

The mechanisms that underlie the extensive phenotypic diversity in genetic disorders are poorly understood. Here, we develop a large-scale assay to characterize the functional valence (gain or loss-of-function) of missense variants identified in UBE3A, the gene whose loss-of-function causes the neurodevelopmental disorder Angelman syndrome. We identify numerous gain-of-function variants including a hyperactivating Q588E mutation that strikingly increases UBE3A activity above wild-type UBE3A levels. Mice carrying the Q588E mutation exhibit aberrant early-life motor and communication deficits, and individuals possessing hyperactivating UBE3A variants exhibit affected phenotypes that are distinguishable from Angelman syndrome. Additional structure-function analysis reveals that Q588 forms a regulatory site …

Putting Nature Centre Stage? The Challenges Of ‘Mainstreaming’ Biodiversity In The Planning Process, Olivia Wilson

School of Geography, Earth and Environmental Sciences

No abstract provided.

Interspecies Variation In Hominid Gut Microbiota Controls Host Gene Regulation, Amanda L. Muehlbauer, Allison L. Richards, Adnan Alazizi, Michael B. Burns, Andres Gomez, Jonathan B. Clayton, Klara Petrzelkova, Camilla Cascardo, Justyna Resztak, Xiaoquan Wen, Roger Pique-Regi, Francesca Luca, Ran Blekhman

Biology: Faculty Publications and Other Works

The gut microbiome exhibits extreme compositional variation between hominid hosts. However, it is unclear how this variation impacts host physiology across species and whether this effect can be mediated through microbial regulation of host gene expression in interacting epithelial cells. Here, we characterize the transcriptional response of human colonic epithelial cells in vitro to live microbial communities extracted from humans, chimpanzees, gorillas, and orangutans. We find that most host genes exhibit a conserved response, whereby they respond similarly to the four hominid microbiomes. However, hundreds of host genes exhibit a divergent response, whereby they respond only to microbiomes from specific …

Silver Bow Creek Butte Area Npl Site 2022 Draft Butte Priority Soils Operable Unit Interim Site-Wide Groundwater Monitoring Qapp. Consent Decree- Civil Action No. Cv 89-039-Bu-She, Josh Bryson

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Are Sustainable Drainage Systems (Suds) Effective At Retaining Dissolved Trace Elements?, Jasmine Humphrey, Chris Rowett, Jonathan Tyers, Mark Gregson, Sean Comber

School of Geography, Earth and Environmental Sciences

No abstract provided.

Designing Environmentally Responsible And Highly Effective Bioorthogonally Functionalized Chiral Mri Contrast Agents, Karley Breann Maier

Dissertations and Theses

Magnetic resonance imaging (MRI) revolutionized diagnostic imaging and modernized the characterization of numerous diseases. The clinical success of MRI is in large part due to the employment of gadolinium-based contrast agents (GBCAs). Due to sensitivity limitations, GBCAs are indicated at markedly high dosages (~1 g Gd³⁺ per exam). The routine use of such large quantities of gadolinium poses significant health and environmental risks. There are growing concerns over the effects of dechelation of the metal in vivo and the possible effect of resulting gadolinium deposition. Concurrently, there is a rising awareness of gadolinium anomalies borne by GBCAs which undergo …

A Biocultural Analysis Of The Impacts Of Interactions Between West Africans And Europeans During The Trans-Atlantic Trade At Elmina, Ghana, Heidi Ellen Miller

USF Tampa Graduate Theses and Dissertations

This project utilizes a biocultural approach to assess the demographics and health of the West African population from Elmina, Ghana. Elmina, selected by the Portuguese in 1482 as the site of the first European trade fort in sub-Saharan Africa, grew from a small coastal fishing village to a large settlement over the course of more than 400 years of trade and cultural entanglement. Taken over by the Dutch and then ceded to the British, the people of Elmina navigated significant cultural changes, changes and experiences that can be detected in their skeletal remains. Bioarchaeological research concerned with the effects of …

Supplmentary Feeding And Management Strategies To Overcome Drought Situations On Three High Producing New Zealand Seasonal Dairy Farms, S. H. Benson, P. N. P. Matthews

IGC Proceedings (1977-2023)

This paper investigates the outcomes of the management strategies to overcome dry summer conditions on three New Zealand seasonal supply dairy farms where the summer management philosophy is towards production rather than survival aimed at giving the farmer control rather than accepting the unreliable production outcomes often achieved. Actual data collected from the case farms as part of a large on-farm monitoring programme was used to model the dry 1998/99 season. This was compared with simulated models for an average season to estimate milksolids responses (g milksolids (MS)/kg DM) and net returns (cents/kg DM) to the additional feeds used. In …

A Simulation Model To Evaluate Supplementation Of Tropical Forage Diets For Dairy Cows, A. G. Assis, O. F. Campos, J. Dijkstra, J. France

IGC Proceedings (1977-2023)

A dynamic model of digestion kinetics has been built to evaluate dairy cattle diets based on tropical feeds and to estimate the potential of tropical forages for milk production associated with available supplements. Results of simulation were very consistent showing that grazed elephant grass alone can supply nutrients for cow maintenance and yield of 7.10 kg milk/day. Nevertheless, to produce 25 kg/day on grazed elephant grass, a dairy cow would need to be supplemented with 5.85 kg/day of a mixture of cottonseed meal (50%) plus ground maize (50%), while on maize silage it would be necessary 4.15 kg of the …

Performance Of Beef Heifers Of Various Genetic Groups, Supplemented Or Not, In Coastcross Pastures, Armando De A. Rodrigues, Geraldo M. Da Cruz, Rogério T. Barbosa, Maurício M. De Alencar, Luciano De A. Corrêa, Gilson P. De Oliveira

IGC Proceedings (1977-2023)

The objective of this study was to determine whether the performance of beef heifers of different genetic groups was affected by breed x nutritional environment interactions. Sixty four weaned heifers, 16 per genetic group: ½ Angus + ½ Nellore (AN), ½ Canchim + ½ Nellore (CN), ½ Simmental + ½ Nellore (SN) and pure Nellore (NE), were used with or without 3.0 kg of concentrate.animal^-1 .day^-1 in a fertilized coastcross pasture under rotational grazing system. There were effects of genetic group and supplementation (P< 0.05) on the weight and age at first estrus, but there was no interaction between them. In a rotational grazing system with 4000 kg of available dry matter per hectare with 13% of crude protein, the crossbred AN, supplemented or not, was more precocious (111 days) than Nellore heifers, showing the first estrus at 356 days of age and 324 kg of live weight.

Animal Performance On Brachiaria Brizantha Alone Or Supplemented With Concentrate Or Protein Bank Of Leucaena Leucocephala, Antonio João Lourenço, Paulo Roberto Leme, Marcelo De Queiroz Manella

IGC Proceedings (1977-2023)

The experiment was carried out at the Instituto Zootecnia, Nova Odessa, SP, Brasil, from June/1998 to March/2000 (634 days), and the liveweight gains of Nelore steers was evaluated, per animal and per area, on Brachiaria brizantha alone (T₁), B. brizantha + Leucaena leucocephala (T₂), B. brizantha + supplemental feeding during the dry season (T₃) and B. brizantha + supplemental feeding during the dry and rainy season (T₄). The experimental design was a randomized block, with four replications each one composed by three paddocks rotationally grazed by Nelore steers. Mean weight gain per …

Hydrolysis Of Rice Straw For Production Of Soluble Sugars, Mahmoud El-Wany

Archived Theses and Dissertations

No abstract provided.

A Statistical-Mining Techniques’ Collaboration For Minimizing Dimensionality In Ovarian Cancer Data, Mohamed Attia, Maha Farghaly, Mohamed Hamada, Amira M. Idrees Ami

Future Computing and Informatics Journal

A feature is a single measurable criterion to an observation of a process. While knowledge discovery techniques successfully contribute in many fields, however, the extensive required data processing could hinder the performance of these techniques. One of the main issues in processing data is the dimensionality of the data. Therefore, focusing on reducing the data dimensionality through eliminating the insignificant attributes could be considered one of the successful steps for raising the applied techniques’ performance. On the other hand, focusing on the applied field, ovarian cancer patients continuously suffer from the extensive analysis requirements for detecting the disease as well …

Josue Villalobos: Taylor Shaped Me, Taylor University

2021 Website News Stories

No abstract provided.

Early Land Plants Have Unique Lipid Profile, Deepshila Gautam

3 Minute Thesis Competition

No abstract provided.

Folic Acid-Carbon Dots-Doxorubicin Nanoparticles As Cancer Theranostics, Michael Tetteh

3 Minute Thesis Competition

No abstract provided.

Boosting Brain Waves Improves Memory, Richard J. Addante, Mairy Yousif, Rosemarie Valencia, Constance Greenwood, Raechel Marino

Psychology Student Publications

Have you ever wanted to improve your memory? Or have you struggled to remember what you studied? Memory uses special patterns of activity in the brain. This experiment tested a new way to create brain wave patterns that help with memory. We wanted to see if we could improve memory by using lights and sounds that teach the brain waves to be in sync. People wore special goggles that made flashes of light and headphones that made beeping noises. This trained the brain through a process called entrainment. The entrainment put the brain in sync at a specific brain wave …

The Utah Statesman, November 22, 2021, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Relationship Between Number Of Instructional Minutes And Science And Mathematics Achievement In Elementary Schools, Gwendolyn Randolph

Dissertations

ABSTRACT

The Next Generation Science Standards and the Common Core Mathematics Standards were created to assist U.S.A. school districts in providing the rigorous instruction needed to equip all students for college and career readiness and citizenship. Many minority students in the U.S.A. specifically, those in disadvantaged communities are still showing deficits in mathematics and science. The relationship between the number of instructional minutes and science and mathematics achievement of fourth grade students on the Northwest Education Association (NWEA) assessment was explored. Research questions addressed the degree of mathematics and science integration in school programming, number of minutes allocated to science …

Gamma Oscillatory Deficits In Schizophrenia And Its Modeling In Rodents As A Biomarker For Drug Development, Ummear Raza

3 Minute Thesis Competition

No abstract provided.

Rapid-Onset Anti-Stress Effects Of A Kappa-Opioid Receptor Antagonist, Ly2795050, Against Immobility In An Open Space Swim Paradigm In Male And Female Mice, Caroline Baynard, Thomas E. Prisinzano, Eduardo R. Butelman

Pharmaceutical Sciences Faculty Publications

The kappa-opioid receptor (KOR) / dynorphin system is implicated with behavioral and neurobiological effects of stress exposure (including heavy exposure to drugs of abuse) in translational animal models. Thus some KOR-antagonists can decrease the aversive, depressant-like and anxiety-like effects caused by stress exposure. The first generation of selective KOR-antagonists have slow onsets (hours) and extremely long durations of action (days-weeks), in vivo. A new generation of KOR antagonists with rapid onset and shorter duration of action can potentially decrease the effects of stress exposure in translational models, and may be of interest for medication development. This study examined the …

Blood Donation Fear, Perceived Rewards, Self-Efficacy, And Intention To Return Among Whole Blood Donors In China: A Social Cognitive Perspective, Zhong Li, Shuge Lei, Xiamoing Li Ph.D., Yilun Zhao, Yudong Dai, Shengxuan Jin, Qiang Fu, Xubing Cai, Zhenping Lin, Xiaoming Tu

Faculty Publications

With the increasing demand from aging population and seasonal blood shortage, recruiting and retaining blood donors has become an urgent issue for the blood collection centers in China. This study aims to understand intention to donate again from a social cognitive perspective among whole blood donors in China through investigating the association between the blood donation fear, perceived rewards, self-efficacy, and intention to return. A cross-sectional survey was conducted in six cities, which are geographically and socioeconomically distinct areas in Jiangsu, China. Respondents completed a self-administrated questionnaire interviewed by two well-trained medical students. A total of 191 blood donors were …

Boosting Brain Waves Improves Memory, Richard J. Addante, Mairy Yousif, Rosemarie Valencia, Constance Greenwood, Raechel Marino

Psychology Faculty Publications

Have you ever wanted to improve your memory? Or have you struggled to remember what you studied? Memory uses special patterns of activity in the brain. This experiment tested a new way to create brain wave patterns that help with memory. We wanted to see if we could improve memory by using lights and sounds that teach the brain waves to be in sync. People wore special goggles that made flashes of light and headphones that made beeping noises. This trained the brain through a process called entrainment. The entrainment put the brain in sync at a specific brain wave …