Digital Commons Network^™

Assessing The Use Of Smartphones In Agriculture, Katherine Mary Carpenter

Theses

Smartphones are an as yet untapped resource available to agriculture. They are ubiquitous across the globe yet have not previously been tested as a resource available to farmers. Imaging methods such as unmanned aerial vehicles (UAV) and satellite imaging have been well-explored and employed in various aspects of agriculture; however, such methods can be cost-prohibitive and at the mercy of another company or agency. If smartphones could be shown to capture color in such a way that relates in a quantifiable way to data measured by laboratory-grade equipment they could prove to be extremely valuable to farmers. Cutting out expensive …

Does Bedtime Music Listening Improve Subjective Sleep Quality And Next-Morning Well-Being In Young Adults? A Randomized Cross-Over Trial, Nadyana M. Majeed, Verity Y. Q. Lua, Jun Sen Chong, Zoey Lew, Andree Hartanto

Research Collection School of Social Sciences

Previous research has found that young adults exhibit patterns of poor sleep and that poor sleep is associated with a host of negative psychological consequences. One potential intervention to improve sleep quality is listening to music at bedtime. Although there exist previous works investigating the efficacy of listening to music as a form of sleep aid, these works have been hindered by statistically weak designs, a lack of systematic investigation of critical characteristics of music that may affect its efficacy, and limited generalizability. In light of the limitations in the existing literature, a 15-day randomized cross-over trial was carried out …

Effect Of 3 Days Of Oral Azithromycin On Young Children With Acute Diarrhea In Low-Resource Settings: A Randomized Clinical Trial, Antibiotics For Children With Diarrhea (Abcd) Study Group, Tahmeed Ahmed, Farah Naz Qamar, Mohammad Tahir Yousafzai, Shahida Qureshi, Sadia Shakoor, Rozina Thobani, Aneeta Hotwani, Furqan Kabir, Jan Mohammed

Department of Paediatrics and Child Health

Importance: World Health Organization (WHO) guidelines do not recommend routine antibiotic use for children with acute watery diarrhea. However, recent studies suggest that a significant proportion of such episodes have a bacterial cause and are associated with mortality and growth impairment, especially among children at high risk of diarrhea-associated mortality. Expanding antibiotic use among dehydrated or undernourished children may reduce diarrhea-associated mortality and improve growth.
Objective: To determine whether the addition of azithromycin to standard case management of acute nonbloody watery diarrhea for children aged 2 to 23 months who are dehydrated or undernourished could reduce mortality and improve linear …

Mitochondrial Aberrations During The Progression Of Disuse Atrophy Differentially Affect Male And Female Mice, Megan E. Rosa-Caldwell, Seongkyun Lim, Wesley S. Haynie, Jacob L. Brown, David E. Lee, Kirsten R. Dunlap, Lisa T. Jansen, Tyrone A. Washington, Michael P. Wiggs, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Background

Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse-induced muscle atrophy. Little data exist on early mechanisms contributing to onset of these pathologies, nor is it known how they differ between sexes. The purpose of this study was to examine differential and conserved responses to mitochondrial quality control in male and female mice during the development and progression of disuse-induced atrophy.

Methods

One hundred C57BL/6J mice (50 male and 50 female) were hindlimb unloaded to induce disuse atrophy for 0 (con), 24, 48, 72, or 168 h. …

A Proposed Mechanism For Financial Reporting On Sustainable Investment And Its Role In Achieving Value Added - Applied In The Iraqi Midland Refineries Company-, Mohammed Ataallah Ali, Salman Hussin Abdullah

Journal of Economics and Administrative Sciences

The research aims to develop a proposed mechanism for financial reporting on sustainable investment that takes the specificity of these investments. To achieve this goal, the researcher used (what if scenario) where the future financial statements were prepared for the year 2026, after completion of the sustainable project and operation, as the project requires four years to be completed. The researcher relied on the results of the researchers collected from various modern sources relevant to the research topic and published on the internet, and the financial data and information obtained to assess the reality of the company's activity and its …

Sigesn Light-Emitting Devices: From Optical To Electrical Injection, Yiyin Zhou

Graduate Theses and Dissertations

Si photonics is a fast-developing technology that impacts many applications such as data centers, 5G, Lidar, and biological/chemical sensing. One of the merits of Si photonics is to integrate electronic and photonic components on a single chip to form a complex functional system that features compact, low-cost, high-performance, and reliability. Among all building blocks, the monolithic integration of lasers on Si encountered substantial challenges. Si and Ge, conventional epitaxial material on Si, are incompetent for light emission due to the indirect bandgap. The current solution compromises the hybrid integration of III-V lasers, which requires growing on separate smaller size substrates …

Sleeping With The Enemy: Examining The Relationship Between Sleep And Pain In Post-9/11 Veterans, John L. Schwartz Jr.

Psychology Theses & Dissertations

United States veterans are a diverse group of individuals, yet as a result of their service, they share a unique set of customs, traditions, and values. Post-9/11 veterans are more likely to experience elevated levels of pain and poor sleep quality compared to their civilian counterparts; however, little is known about how beliefs related to veterans’ pain impact their sleep and how levels of pain acceptance influence the sleep-pain association. This study examined relationships between sleep and pain in a sample of 102 post-9/11 veterans. Results support associations between pain and sleep identified in other populations. Positive correlations were found …

Emotion Regulation Variability And Relationship Functioning In Emerging Adulthood, Laura B. Kenneally

Psychology Theses & Dissertations

Emotion regulation is a transdiagnostic factor that functions as a crucial contributor to individual well-being and social functioning. Research seeking to identify adaptive or maladaptive strategies of emotion regulation has often focused on individual strategies, though emerging evidence suggests that what constitutes “adaptive” regulation is often context-dependent. Having a large repertoire of emotion regulation strategies that one is willing to use at different rates has been termed “emotion regulation variability,” and has been linked to positive individual outcomes. While the benefits of emotion regulation variability have been demonstrated on an individual level, the impact on romantic relationships has yet to …

Hydrothermal Processes For Extraction And Conversion Of Biomass To Produce Biofuels And Value-Added Products, Anuj Hemant Thakkar

Civil & Environmental Engineering Theses & Dissertations

An integrated biorefinery approach based on subcritical hydrothermal processes was developed to maximize utilization of biomass components by producing multiple products. Biomass from various sources like agricultural waste (lignocellulose), food waste (spent yeast), and dedicated cultivation (micro-algae) was used in this research.

Corn stover (agricultural waste) was hydrothermally pretreated to remove lignin and xylan while preserving most of the glucan. The pretreated corn stover was utilized to produce levulinic acid (thermochemically) and fermentable sugars (biochemically). The solid residue generated during levulinic acid production was utilized to produce biocarbon electrode material. The results generated from the experiments were used for designing …

Shipboard Lidar As A Tool For Remotely Measuring The Distribution And Bulk Characteristics Of Marine Particles, Brian Leigh Collister

OES Theses and Dissertations

Light detection and ranging (lidar) can provide remote estimates of the vertical distribution of optical properties in the ocean, potentially revolutionizing our ability to characterize the spatial structure of upper ocean ecosystems. However, challenges associated with quantifying the relationship between lidar measurements and biogeochemical properties of interest have prevented its adoption for routinely mapping the vertical structure of marine ecosystems. To address this, we developed a shipboard oceanographic lidar that measures attenuation (α) and linear depolarization (δ) at scales identical to those of in-water optical and biogeochemical measurements. The instrument’s ability to resolve the distribution of optical and biogeochemical properties …

Design, Synthesis And Characterization Of Carbohydrate Based Macrocycles, Photo Responsive Derivatives, And Glycoconjugates Based Low Molecular Weight Gelators, Surya Bahadur Adhikari

Chemistry & Biochemistry Theses & Dissertations

Functional glycoconjugates are important classes of compounds with many applications in different research fields. Our lab has been studying the synthesis and applications of different classes of glycoconjugates ranging from macrocycles to sugar heterocycle derivatives. Due to the importance of these compounds, our research is based on development of synthetic methods for various carbohydrate derivatives. This dissertation includes introduction and overview of projects, followed by the synthesis and studies of several different series of glycomacrolactones. The second project focuses on two classes of photoresponsive molecules, the coumarins and diarylethenes. The third project involves the synthesis and self-assembling properties of isoxazole-based …

Phytoplankton Community Response To Upwelling Events: Distribution And Abundance Investigated Using Genomic Methods, Sveinn V. Einarsson

OES Theses and Dissertations

Upwelling events are known to support blooms of phytoplankton, important primary producers at the base of the oceanic food web. Phytoplankton community structure changes in response to upwelling support higher trophic level growth and increased efficiency of carbon export from the euphotic zone. While these events occur globally, this study examined upwelling in coastal regions, where alongshore winds can drive Ekman transport and upwelling of deeper waters. The two upwelling regimes examined were the California Current System and the Alaskan Beaufort Sea. In the California Current System, the relative diatom community composition was examined using 18S sequencing to determine how …

The Effects Of Depression, Anxiety, And Stress On College Students: Examining The Role Of Mental Health Self-Efficacy On Willingness To Engage In Mental Health Services, Leeanna L. Golembiewski

Psychology Theses & Dissertations

Relative to younger ages, mental health problems are more prevalent among college students (Pedrelli et al., 2015) and nearly 20% of U.S college students are diagnosed each year with a mental health problem (Blanco et al., 2008). College students’ self-efficacy may influence mental health outcomes by impacting an individual’s decision to change their behavior and execute a course of action (Bresó et al., 2011). Mental health may also be influenced by the degree of willingness that an individual possesses, such that those who are more willing to seek mental health treatment are also more likely to follow through and seek …

Assessment Of The Hydrograv® Adapt Variable Height Secondary Clarifier Inlet At Hrsd Nansemond Treatment Plant, Matthew Poe

Civil & Environmental Engineering Theses & Dissertations

The Hampton Roads Sanitation District (HRSD) recently completed the first North American and center driven installation of the Hydrograv® Adapt Variable Height Secondary Clarifier Inlet (Adapt) at HRSD’s Nansemond Treatment Plant. This is a variable height inlet structure designed to decrease clarifier effluent turbidity and maintain low turbidity during high flow events. Low turbidity is achieved by feeding the secondary clarifier influent within the solids blanket during dry weather conditions and lifting the inlet structure during wet weather conditions to avoid disrupting the blanket. The Adapt clarifier was monitored alongside an identical fixed inlet clarifier to assess performance. Both clarifiers …

A Copula Model Approach To Identify The Differential Gene Expression, Prasansha Liyanaarachchi

Mathematics & Statistics Theses & Dissertations

Deoxyribonucleic acid, more commonly known as DNA, is a complex double helix-shaped molecule present in all living organisms and hosts thousands of genes. However, only a few genes exhibit differential expression and play a vital role in a particular disease such as breast cancer. Microarray technology is one of the modern technologies developed to study these gene expressions. There are two major microarray technologies available for expression analysis: Spotted cDNA array and oligonucleotide array. The focus of our research is the statistical analysis of data that arises from the spotted cDNA microarray. Numerous models have been proposed in the literature …

The Investigations Of Nps Modulated Immunity And Immunometabolism, Brittney Leigh Ruedlinger

Biomedical Sciences Theses & Dissertations

Cancers remain in the top noncommunicable diseases responsible for premature mortality. The heterogeneity among cancers and within tumors makes treating them ever more challenging. Our misfortune for developing cures is mocked by cancer, with the lowest probability of success (PoS) through clinical trials and FDA approval. At the basic level, there are generally two broad gaps impeding cancer eradication: the unidentified shared mechanism(s) exploited by all cancers and the therapeutic approach to intervene. Nanosecond pulse stimulation (NPS) offers a unique approach since its broad impacts intersect those often hijacked by oncogenesis. Metabolic pathways, known for dysfunctions among cancers, share a …

Synthesis And Characterization Of 4,6-Protected Glucosamine Derivatives And Branched Glycoconjugates, Jonathan Bietsch

Chemistry & Biochemistry Theses & Dissertations

Low molecular weight gelators (LMWGs) are small molecules that self-assemble in appropriate solvents to form three dimensional networks that immobilize the solvent, creating a supramolecular gel. The self-assembly of LMWGs occurs through non-covalent interactions such as hydrogen bonding, aromatic interactions, donor-acceptor interactions, Van der Waals interactions, hydrophobic forces, halogen bonding, etc. Due to self-assembly occurring through reversible non-covalent interactions, supramolecular gels can undergo a gel to solution transformation. Because of this, these materials can be sensitive to external stimuli such as temperature changes, pH changes, and other stimuli that effect non-covalent interactions. This makes the synthesis of LMWG’s an appealing …

Effects Of Static And Dynamic Visuals On The Learning Of Science Concepts In The Secondary-School Classroom, Theodore Johnson

Doctoral Dissertations

The current study is grounded in the cognitive theory of multimedia learning. The investigator considered how embedding science text with visuals could affect secondary-school students' ability to retain the information they learn (rote learning) and transfer the new knowledge to an unfamiliar problem (meaningful learning). Furthermore, this study explored how the type of visuals (static versus vs. dynamic visual) and text (audio vs. print) affect science learning. The data generated was sourced from student participants in a secondary-school biology classroom. The purpose of this study was to investigate how prior knowledge and the integration of information modalities (i.e., text, audio, …

Understanding The African American Male Student Experience Of Being Diagnosed With Emotional Disturbance Through The Use Of Counter-Storytelling, Sara Ordaz

Doctoral Dissertations

In the U.S. educational system, it is too common to see African American males overrepresented in special education classrooms, including segregated special education settings. African American males continuously experience disproportionate representation and placement in special education, especially under the label of ED (Harry & Anderson, 1994). Twice as many African American students in the United States are receiving services for Emotional Disturbance than their White counterparts.

Students who are labeled with ED have the lowest educational outcomes as well as lower success rates in life than any other disability classification (Merrrell & Walker, 2004). The consequences of the ED label …

The Influence Of Emotion Regulation And Neural Cognitive Control On Distress Tolerance, Alicia L. Milam

Psychology Theses & Dissertations

Tolerance of negative emotions has been associated with transdiagnostic negative mental health outcomes. Theory and research implicate emotion regulation and cognitive control as factors in tolerance of negative emotions. But their unique contributions to tolerance of negative emotions and interdependency have been unclear due to methodological limitations. This study aimed to explicate cognitive and emotional factors affecting distress tolerance in a non-clinical sample of emerging adults. Undergraduate psychology students completed self-report measures of emotion regulation ability and tolerance of negative emotions. The N2 ERP component elicited by a Go-NoGo task was also used as a neurophysiological marker of cognitive control …

Covid-19, Technology, And The Math Classroom: Changes, Obstacles, And Victories Integrating Digitally, Lauren Fifield Bellamy

Teaching & Learning Theses & Dissertations

Secondary math teachers faced new experiences and struggles this past virtual school year due to the global COVID-19 pandemic. Nine secondary math teachers from a school division in southeastern Virginia participated in this qualitative single case study. Data collection included individual semi-structured interviews and technology integration artifacts. Through a three round coding process, ten themes emerged to answer the following three research questions: 1) In terms of curriculum, teaching methods, and assessments, how did teachers describe their pedagogical change in virtual learning? 2) How do teachers perceive student performance has changed within the virtual learning space? 3) From teachers’ perspectives, …

Intention-Behavior Discrepancies For Alcohol Consumption Among College Students, Emily Kaye Junkin

Psychology Theses & Dissertations

Unplanned drinkers may experience elevated risk for drinking-related harm. Research examining unplanned drinking focuses on the unplanned nature of a drinking episode (i.e., did the student drink when no drinking was planned), yet this does not capture the importance of the unintended quantity consumed. For instance, a discrepancy between drinking intentions and actual consumption has the potential to differentially impact alcohol-related outcomes beyond what is accounted for by unplanned drinking episodes. Further, research has not investigated how college students’ unintended drinking is associated with alcohol-related consequences. Moreover, utilization of protective behavioral strategies (PBS) has been shown to decrease negative outcomes …

Estimating The Risk Of Future Plastic Marine Debris Resulting From The Urban Coastal Built Environment, Kelly C. Jones

OES Theses and Dissertations

The growing urban built environment in the coastal zone poses an unknown risk to the marine biosphere as a source of marine debris. Plastic, since its introduction in the mid- 1900s, is now used in nearly all aspects of human life. Growth in human population and urbanization in coastal zones has resulted in the accumulation of large stocks of plastic in the coastal built environment, and these stocks are still growing exponentially. The coastal zone is exposed to a number of hazards including storms, tsunamis, and sea level rise, and most of these hazards are expected to change in the …

Integrated Processing Of Municipal Solid Waste For Maximizing Waste Reduction, Carbon Recovery And Fuel Production, Kameron J. King

Civil & Environmental Engineering Theses & Dissertations

Nationally and internationally, waste generation is increasing and along with it negative environmental impacts. Many people think waste ends at disposal; however, environmental impacts have already begun. Unfortunately, 50% of waste ends up in a landfill which is the third largest source of human related methane emissions and a leading cause of global climate change. This study investigated a novel waste management strategy in hopes of mitigating negative environmental effects caused by conventional waste management practices. The novelty of the study lies in the development of an integrated method of hydrothermal carbonization and an anaerobic digestion (HTC + AD) process …

Genetically Engineered Thermosynechococcus Elongatus Bp1: Assessment Of Potential Biorisks And Biofuel Production, Thu Ho Anh Nguyen-Jones

Chemistry & Biochemistry Theses & Dissertations

According to the International Energy Outlook 2019, released by the U.S. Energy Information Administration, it is projected that the energy consumption will increase up to 50% between 2018 and 2050 worldwide. As fossil fuel being a finite source of energy with the risk of depletion, many countries are now facing an energy security crisis. Therefore, it is important to develop other renewable and sustainable energy sources that will allow countries to shift away from depending on fossil fuels. Among several types of renewable energy, biofuel production using genetically engineered cyanobacteria is capturing much interest due to its many advantages. Different …

Mechanisms Of Stress Survival In Gram Positive Bacterial Pathogens, Asia Poudel

Chemistry & Biochemistry Theses & Dissertations

Anaerobic Gram-positive bacteria are not a well-characterized group but include many human pathogens that are resilient against stresses caused by the human immune system or by antibiotic treatment. This dissertation investigated the survival mechanisms of two clinically relevant Gram-positive organisms, Clostridioides difficile and Cutibacterium acnes under extracellular stresses. The response of the opportunistic skin pathogen Cutibacterium acnes to nanosecond electric pulses is characterized and found that growth in a biofilm, which usually protects bacteria from stress, renders this species more killable by this treatment. In addition, the stringent response (SR), a conserved bacterial stress survival mechanism, is studied in the …

Tunable Compressive Mechanical Behavior Of Ice-Templated Materials, Sashanka Akurati

Mechanical & Aerospace Engineering Theses & Dissertations

The inherent hierarchical microstructural organization in natural materials is responsible for their excellent mechanical properties beyond that predicted by the simple rule-of-mixtures. Further exhibit synergy between strength and toughness, otherwise mutually exclusive in brittle materials. Conventional processing methods are unable to replicate hierarchical microstructures in engineering ceramics akin to that observed in natural materials. Ice-templating has emerged as a potential technique to fabricate bioinspired hierarchical materials. This process involves simultaneous unidirectional solidification and phase segregation of aqueous suspensions. Ice-templated porous ceramic materials have received significant attention for overcoming several limitations of conventional ceramic foams currently used in numerous engineering applications. …

Deletion Of Type Viii Collagen Reduces Blood Pressure, Increases Carotid Artery Functional Distensibility And Promotes Elastin Deposition, Amanda L Mohabeer, Jeffrey T Kroetsch, Meghan Mcfadden, Negin Khosraviani, Thomas J Broekelmann, Guangpei Hou, Hangjun Zhang, Yu-Qing Zhou, Minyao Wang, Anthony O Gramolini, Robert P Mecham, Scott P Heximer, Steffen-Sebastian Bolz, Michelle P Bendeck

2020-Current year OA Pubs

Arterial stiffening is a significant predictor of cardiovascular disease development and mortality. In elastic arteries, stiffening refers to the loss and fragmentation of elastic fibers, with a progressive increase in collagen fibers. Type VIII collagen (Col-8) is highly expressed developmentally, and then once again dramatically upregulated in aged and diseased vessels characterized by arterial stiffening. Yet its biophysical impact on the vessel wall remains unknown. The purpose of this study was to test the hypothesis that Col-8 functions as a matrix scaffold to maintain vessel integrity during extracellular matrix (ECM) development. These changes are predicted to persist into the adult …

Unmasc: Tumor-Only Variant Calling With Unmatched Normal Controls, Paul Little, Heejoon Jo, Alan Hoyle, Angela Mazul, Xiaobei Zhao, Ashley H Salazar, Douglas Farquhar, Siddharth Sheth, Maheer Masood, Michele C Hayward, Joel S Parker, Katherine A Hoadley, Jose Zevallos, D Neil Hayes

2020-Current year OA Pubs

Despite years of progress, mutation detection in cancer samples continues to require significant manual review as a final step. Expert review is particularly challenging in cases where tumors are sequenced without matched normal control DNA. Attempts have been made to call somatic point mutations without a matched normal sample by removing well-known germline variants, utilizing unmatched normal controls, and constructing decision rules to classify sequencing errors and private germline variants. With budgetary constraints related to computational and sequencing costs, finding the appropriate number of controls is a crucial step to identifying somatic variants. Our approach utilizes public databases for canonical …

Genetic Liability To Cannabis Use Disorder And Covid-19 Hospitalization, Alexander S Hatoum, Claire L Morrison, Sarah M C Colbert, Evan A Winiger, Emma C Johnson, Arpana Agrawal, Ryan Bogdan

2020-Current year OA Pubs

BACKGROUND: Vulnerability to COVID-19 hospitalization has been linked to behavioral risk factors, including combustible psychoactive substance use (e.g., tobacco smoking). Paralleling the COVID-19 pandemic crisis have been increasingly permissive laws for recreational cannabis use. Cannabis use disorder (CUD) is a psychiatric disorder that is heritable and genetically correlated with respiratory disease, independent of tobacco smoking. We examined the genetic relationship between CUD and COVID-19 hospitalization.

METHODS: We estimated the genetic correlation between CUD (case:

RESULTS: Genetic vulnerability to COVID-19 was correlated with genetic liability to CUD (

CONCLUSIONS: Problematic cannabis use and vulnerability to serious COVID-19 complications share genetic underpinnings …