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Articles 162121 - 162150 of 819611

Full-Text Articles in Entire DC Network

A Large West Antarctic Ice Sheet Explains Early Neogene Sea-Level Amplitude, J. W. Marschalek, L. Zurli, F. Talarico, De Flierdt T Van, P. Vermeesch, A. Carter, F Beny, V. Bout-Roumazeilles, F. Sangiorgi, S. R. Hemming, L. F. Pérez, F. Colleoni, J. G. Prebble, Peer Te Van, M. Perotti, A. E. Shevenell, I Browne, Dk Kulhanek, R. Levy, D Harwood, N. B. Sullivan, S. R. Meyers, E. M. Griffith, C. D. Hillenbrand, E. Gasson, M. J. Siegert, B Keisling, K. J. Licht, G. Kuhn, Jp Dodd, C. Boshuis, Santis L De, Rm Mckay, Jeanine Ash, F Beny, Im Browne, Giuseppe Cortese, Santis L De, Jp Dodd, Oliver M. Esper, Jenny A. Gales, Dm Harwood, Saki Ishino, Ba Keisling, S Kim, S Kim, Dk Kulhanek, Jan Sverre Laberg, R. Mark Leckie, Rm Mckay, J Müller, Mo Patterson, Bw Romans, Oe Romero, F. Sangiorgi, O Seki, Ae Shevenell, Sm Singh, De Sousa Im Cordeiro, St Sugisaki, T Van De Flierdt, Peer Te Van, W Xiao, Z Xiong Dec 2021

A Large West Antarctic Ice Sheet Explains Early Neogene Sea-Level Amplitude, J. W. Marschalek, L. Zurli, F. Talarico, De Flierdt T Van, P. Vermeesch, A. Carter, F Beny, V. Bout-Roumazeilles, F. Sangiorgi, S. R. Hemming, L. F. Pérez, F. Colleoni, J. G. Prebble, Peer Te Van, M. Perotti, A. E. Shevenell, I Browne, Dk Kulhanek, R. Levy, D Harwood, N. B. Sullivan, S. R. Meyers, E. M. Griffith, C. D. Hillenbrand, E. Gasson, M. J. Siegert, B Keisling, K. J. Licht, G. Kuhn, Jp Dodd, C. Boshuis, Santis L De, Rm Mckay, Jeanine Ash, F Beny, Im Browne, Giuseppe Cortese, Santis L De, Jp Dodd, Oliver M. Esper, Jenny A. Gales, Dm Harwood, Saki Ishino, Ba Keisling, S Kim, S Kim, Dk Kulhanek, Jan Sverre Laberg, R. Mark Leckie, Rm Mckay, J Müller, Mo Patterson, Bw Romans, Oe Romero, F. Sangiorgi, O Seki, Ae Shevenell, Sm Singh, De Sousa Im Cordeiro, St Sugisaki, T Van De Flierdt, Peer Te Van, W Xiao, Z Xiong

School of Biological and Marine Sciences

Early to Middle Miocene sea-level oscillations of approximately 40–60 m estimated from far-field records are interpreted to reflect the loss of virtually all East Antarctic ice during peak warmth2. This contrasts with ice-sheet model experiments suggesting most terrestrial ice in East Antarctica was retained even during the warmest intervals of the Middle Miocene. Data and model outputs can be reconciled if a large West Antarctic Ice Sheet (WAIS) existed and expanded across most of the outer continental shelf during the Early Miocene, accounting for maximum ice-sheet volumes. Here we provide the earliest geological evidence proving large WAIS expansions occurred during …

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Beach Hazards: Riu Funana, Cape Verde, C Stokes, G Masselink, T Scott, L Brodie Dec 2021

Beach Hazards: Riu Funana, Cape Verde, C Stokes, G Masselink, T Scott, L Brodie

School of Biological and Marine Sciences

No abstract provided.

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On The Variability Of Flocculated Particle Characteristics In A Shallow Estuary, G Egan, G Chang, Aj Manning, Sg Monismith, Ob Fringer Dec 2021

On The Variability Of Flocculated Particle Characteristics In A Shallow Estuary, G Egan, G Chang, Aj Manning, Sg Monismith, Ob Fringer

School of Biological and Marine Sciences

No abstract provided.

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Lrg1 Is An Adipokine That Mediates Obesity-Induced Hepatosteatosis And Insulin Resistance, Sijia He, Jiyoon Ryu, Juanhong Liu, Hairong Luo, Ying Lv, Paul R. Langlais, Jie Wen, Feng Dong, Zhe Sun, Ravindranath Duggirala Dec 2021

Lrg1 Is An Adipokine That Mediates Obesity-Induced Hepatosteatosis And Insulin Resistance, Sijia He, Jiyoon Ryu, Juanhong Liu, Hairong Luo, Ying Lv, Paul R. Langlais, Jie Wen, Feng Dong, Zhe Sun, Ravindranath Duggirala

School of Medicine Publications

Dysregulation in adipokine biosynthesis and function contributes to obesity-induced metabolic diseases. However, the identities and functions of many of the obesity-induced secretory molecules remain unknown. Here, we report the identification of leucine-rich alpha-2-glycoprotein 1 (LRG1) as an obesity-associated adipokine that exacerbates high fat diet–induced hepatosteatosis and insulin resistance. Serum levels of LRG1 were markedly elevated in obese humans and mice compared with their respective controls. LRG1 deficiency in mice greatly alleviated diet-induced hepatosteatosis, obesity, and insulin resistance. Mechanistically, LRG1 bound with high selectivity to the liver and promoted hepatosteatosis by increasing de novo lipogenesis and suppressing fatty acid β-oxidation. LRG1 …

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Structural Stability Of Short Latency Alfalfa-Based Pastures In The Humid Pampa, Argentina, R. O. Refi, B. Martín Dec 2021

Structural Stability Of Short Latency Alfalfa-Based Pastures In The Humid Pampa, Argentina, R. O. Refi, B. Martín

IGC Proceedings (1977-2023)

The aim of this study was to search the effects of grazing intensity and nitrogen fertilization on the structural stability of a mixed pasture composed by alfalfa (latency group 9), brome grass, tall fescue and white clover, sown in April 1997. Rotational grazing was carried out with dairy cattle with high intensity (HI: up to 3-4 cm) or moderate intensity (LI: up to 8-10 cm), whenever the alfalfa showed basal regrowth. According to a split-plot design, grazing intensities were subdivided to assign three levels of nitrogen fertilization: N0, without fertilization; N1 with 50 kg N/ha per year; and N2 with …

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Late Winter Dietary Overlap Among Greater Rheas And Domestic Herbivores On The Argentinean Flooding Pampa, G. Vacarezza, M. S. Cid, F. Milano Dec 2021

Late Winter Dietary Overlap Among Greater Rheas And Domestic Herbivores On The Argentinean Flooding Pampa, G. Vacarezza, M. S. Cid, F. Milano

IGC Proceedings (1977-2023)

This study evaluates the dietary overlap among greater rheas (Rhea americana L.) sheep and cattle in the Flooding Pampa, Buenos Aires, Argentina during late winter, when is observed the lowest forage availability. The work was carried out with the following forage classes (FC): warm and cool season grasses and forbs (legumes and no-legumes). Diet botanical composition was estimated by microanalysis of faeces. Principal Component Analysis and Kulcyznsky´s index of similarity were used for data analysis. Rhea populations selected diets with higher forb percentages. On the contrary, vegetation structure and their own morpho-physiology conditioned cattle to diets almost exclusively gramineous. …

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Beef Calf Production Using Year-Round Grazing On Tropical Grass Pasture In Summer Combined With Cool Temperate Grass Pasture In Winter, Y. Nakanishi, K. Shindou, S. Watanabe, K. Yamamoto, K. Hagino Dec 2021

Beef Calf Production Using Year-Round Grazing On Tropical Grass Pasture In Summer Combined With Cool Temperate Grass Pasture In Winter, Y. Nakanishi, K. Shindou, S. Watanabe, K. Yamamoto, K. Hagino

IGC Proceedings (1977-2023)

Bahiagrass (Paspalum notatum Fluegge) showed a poor quality with low crude protein in summer but blood biochemical levels of grazing beef cows were similar to drylot feeding cows except of concentration of urea nitrogen. Italian ryegrass (Lolium multiflorum Lam) showed very good quality with high crude protein (about 20 percentage) in winter. And so, suckler cows gained live weight in winter and suckling calves were showed very high growth rate (daily gain was about 1.0 kg). Total live weight gains of grazing cows were higher than those of drylot feeding cows. Postpartum reproductive performances of grazing cows were …

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Winter Grazing And Feeding Systems In Western Canada, Duane H. Mccartney, V. Baron, J. Basarab, E. Okine, G. Lastiwka, A. Depalme, D. Young Dec 2021

Winter Grazing And Feeding Systems In Western Canada, Duane H. Mccartney, V. Baron, J. Basarab, E. Okine, G. Lastiwka, A. Depalme, D. Young

IGC Proceedings (1977-2023)

Beef cow calf producers in Western Canada are looking for methods of extending the grazing season into the winter in order to lower winter feed costs. Dry beef cows were early or late weaned and grazed during the early months of winter on late seeded barley swaths (Hardlum vulgare L.) and compared to cows fed barley silage and free choice barley straw in a feeding yard. The swath grazed barley was late seeded in June and swathed in the silage stage in mid September. Cows successfully swath grazed for three winters from mid November until mid to late February …

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Forage Management For Extending The Grazing Season, David W. Koch, C. M. Lux, J. W. Flake Dec 2021

Forage Management For Extending The Grazing Season, David W. Koch, C. M. Lux, J. W. Flake

IGC Proceedings (1977-2023)

Studies were conducted to determine ways to extend grazing season with forages adequate to meet the needs of grazing animals and to reduce the cost of livestock production. Perennial grasses were swathed, windrowed and left in the field until they were winter-grazed with bred heifers. Corn (Zea mays L.) was stockpiled for winter grazing with lambs and ewes. Windrowed grasses increased in acid detergent fiber (ADF) and neutral detergent fiber (NDF) compared with stored hay, but crude protein content, heifer weight gain and body condition change was similar for both forages. An economic value of $218 ha-1 from …

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Molecular Cartography Of Residue Pesticides On Grape Surface In 3d By Ambient Ionization Tandem Mass Spectrometry, Hung Su, Tiao-Lai Huang, Cheng-Ting Chi, Yi-Tzu Cho, Chi-Wei Lee, Jingyueh Jeng, Jentaie Shiea Dec 2021

Molecular Cartography Of Residue Pesticides On Grape Surface In 3d By Ambient Ionization Tandem Mass Spectrometry, Hung Su, Tiao-Lai Huang, Cheng-Ting Chi, Yi-Tzu Cho, Chi-Wei Lee, Jingyueh Jeng, Jentaie Shiea

Journal of Food and Drug Analysis

Thermal desorption-electrospray ionization tandem mass spectrometry (TD-ESI/MS/MS) was used to characterize the residual pesticides that were collected from the surface of a grape with metallic sampling probes. Fungicides, insecticides, and miticides were detected, where results were validated by simple solvent extraction followed by gas chromatography tandem mass spectrometry and liquid chromatography tandem mass spectrometry analyses. To explore the distribution of pesticide residues on grape surfaces, 149 locations of a grape surface were collected and followed by TD-ESI/MS/MS analysis. The molecular cartography was then generated from analysis of residual pesticides on the grape surface in 3D.

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Variations In Bovine Milk Oligosaccharides After Calving Using P-Aminobenzoic Ethyl Ester Closed-Ring Labeling And Negative Ion Electrospray Lc/Ms/Ms, Han-Ju Chien, Yi-Chun Ma, Yi-Feng Zheng, Cheng-Yu Kuo, Wei-Chen Wang, Guor-Rong Her, Chien-Chen Lai Dec 2021

Variations In Bovine Milk Oligosaccharides After Calving Using P-Aminobenzoic Ethyl Ester Closed-Ring Labeling And Negative Ion Electrospray Lc/Ms/Ms, Han-Ju Chien, Yi-Chun Ma, Yi-Feng Zheng, Cheng-Yu Kuo, Wei-Chen Wang, Guor-Rong Her, Chien-Chen Lai

Journal of Food and Drug Analysis

A strategy was proposed to analyze bovine milk oligosaccharides using p-aminobenzoic ethyl ester (ABEE) closed-ring labeling and C18 capillary liquid chromatography negative ion electrospray tandem mass spectrometry. Linkage specific fragment ions were used to identify oligosaccharide isomers. By constructing the mass chromatograms using linkage specific fragment ions, isomers were differentiated based on m/z values as well as temporal separation provided by liquid chromatography. In addition to disialyllactose and the single isomer lacto-N-neohexaose, four pairs of linkage isomers including 3’/6’-sialyllactose (3’/6’-SL), 3’/6’-sialyllactosamine (3’/6’-SLN), 3’/6’-sialylgalactosyl-lactose (3’/6’-SGL), and lacto-N-tetraose/lacto-N-neotetraose (LNT/LNnT) in bovine milk were investigated. Variations of bovine milk oligosaccharides in a …

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Determination Of Quetiapine And Its Metabolites In Plasma By Field-Enhanced Sample Stacking, Tai-Ling Liu, Li-Shan Fang, Jing-Ru Liou, Jia-Shan Dai, Yen-Ling Chen Dec 2021

Determination Of Quetiapine And Its Metabolites In Plasma By Field-Enhanced Sample Stacking, Tai-Ling Liu, Li-Shan Fang, Jing-Ru Liou, Jia-Shan Dai, Yen-Ling Chen

Journal of Food and Drug Analysis

Quetiapine is an atypical antipsychotic drug that can be used to treat mental disorders, including schizophrenia, bipolar disorder and Alzheimer's disease. Quetiapine is mainly converted into the active metabolites of norquetiapine and 7-hydroxyquetiapine by the liver enzymes CYP3A4 and CYP2D6. In this study, liquid-liquid extraction (LLE) was used as a sample pretreatment method to eliminate interferences in plasma. tert-Butyl methyl ether was chosen as the extraction solvent. Field-enhanced sample injection (FESS), an online preconcentration technique, was used to analyze quetiapine and its metabolites norquetiapine and 7-hydroxyquetiapine in plasma. The optimal separation condition was 120 mM phosphate (pH 4.0) containing …

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Diagnostic Ions Guided 2d-Locating Strategy For Characterization Of Chemical Analogues In Complex Herbal Medicines Using Liquid Chromatography-Ion Mobility-Mass Spectrometry, Meng-Ning Li, Zi-Xuan Zhang, Hui-Ying Wang, Wen Gao, Ping Li, Hua Yang Dec 2021

Diagnostic Ions Guided 2d-Locating Strategy For Characterization Of Chemical Analogues In Complex Herbal Medicines Using Liquid Chromatography-Ion Mobility-Mass Spectrometry, Meng-Ning Li, Zi-Xuan Zhang, Hui-Ying Wang, Wen Gao, Ping Li, Hua Yang

Journal of Food and Drug Analysis

Rapid characterization of chemical analogues in potentially toxic complex matrix was essential for prevention of accidental poisoning. On the basis of the fragment ions possessed not only the same retention times (RT) but the same drift times (DT) on liquid chromatography-ion mobility-mass spectrometry (LC-IM-MS), an alternating frames (AF)-data independent acquisition (DIA) was utilized for simultaneous detection and rapid match of precursor/product ions with a fast switch of low/high collision energy (CE). A diagnostic ions guided 2D-locating strategy was developed for identification of chemical analogues in potentially toxic herbal medicines using LC-IM-MS. Firstly, the 2D-locations (RT, DT) of diagnostic ions were …

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Pharmacokinetics Of Panduratin A Following Oral Administration Of A Boesenbergia Pandurata Extract To Rats, Jihyun Won, Keumhan Noh, Jae-Kwan Hwang, Beom Soo Shin, Wonku Kang Dec 2021

Pharmacokinetics Of Panduratin A Following Oral Administration Of A Boesenbergia Pandurata Extract To Rats, Jihyun Won, Keumhan Noh, Jae-Kwan Hwang, Beom Soo Shin, Wonku Kang

Journal of Food and Drug Analysis

Boesenbergia pandurata and its major active ingredient, panduratin A (PAN), exhibit antibacterial, anti-oxidant, anti-inflammatory, and anti-obesity effects. We explored the time course of the plasma and tissue (in the major organs, gums and skin) concentrations of PAN after oral administration of a B. pandurata extract to rats. Model-dependent analysis was used to quantify the skin distribution of PAN after systemic exposure. The PAN level peaked at 1.12 ± 0.22 μg/mL after 3 h, and then biexponentially decayed with a terminal half-life of 9 h. The mean clearance (Cl/F) was 2.33 ± 0.68 L/h/kg. The PAN levels in organs were in …

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A Novel Nrf2/Are Inhibitor Gossypol Induces Cytotoxicity And Sensitizes Chemotherapy Responses In Chemo-Refractory Cancer Cells, Ya-Chu Tang, Hsin-Huei Chang, Huang-Hui Chen, Jau-Ying Yao, Yu-Tsen Chen, Yung-Jen Chuang, Jang-Yang Chang, Ching-Chuan Kuo Dec 2021

A Novel Nrf2/Are Inhibitor Gossypol Induces Cytotoxicity And Sensitizes Chemotherapy Responses In Chemo-Refractory Cancer Cells, Ya-Chu Tang, Hsin-Huei Chang, Huang-Hui Chen, Jau-Ying Yao, Yu-Tsen Chen, Yung-Jen Chuang, Jang-Yang Chang, Ching-Chuan Kuo

Journal of Food and Drug Analysis

NRF2/ARE signaling pathway is a principal regulator of cellular redox homoeostasis. The stress-induced transcription factor, NRF2, can shield cells from the oxidative damages via binding to the consensus antioxidant-responsive element (ARE) and driving several cyto-protective genes expression. Increasing evidence indicated that aberrant activation of NRF2 in malignant cells may support their survival through various pathways to detoxify chemotherapy drugs, attenuate drug-induced oxidative stress, or induce drug efflux, all of which are crucial in developing drug resistance. Accordingly, NRF2 is a potential drug target for improving the effectiveness of chemotherapy and to reverse drug resistance in cancer cells. A stable ARE-driven …

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Curcumin-Induced Antitumor Effects On Triple-Negative Breast Cancer Patient-Derived Xenograft Tumor Mice Through Inhibiting Salt-Induced Kinase-3 Protein, Tzu-Chun Cheng, John Oliver Sayseng, Shih-Hsin Tu, Ting-Ching Juan, Chia-Lang Fang, You-Cheng Liao, Cheng-Ying Chu, Hui-Wen Chang, Yun Yen, Li-Ching Chen, Yuan-Soon Ho Dec 2021

Curcumin-Induced Antitumor Effects On Triple-Negative Breast Cancer Patient-Derived Xenograft Tumor Mice Through Inhibiting Salt-Induced Kinase-3 Protein, Tzu-Chun Cheng, John Oliver Sayseng, Shih-Hsin Tu, Ting-Ching Juan, Chia-Lang Fang, You-Cheng Liao, Cheng-Ying Chu, Hui-Wen Chang, Yun Yen, Li-Ching Chen, Yuan-Soon Ho

Journal of Food and Drug Analysis

This study demonstrated for the first time that curcumin effectively inhibits the growth of triple-negative breast cancer (TNBC) tumors by inhibiting the expression of salt-induced kinase-3 (SIK3) protein in patient-derived xenografted tumor mice (TNBC-PDX). For TNBC patients, chemotherapy is the only option for postoperative adjuvant treatment. In this study, we detected the SIK3 mRNA expression in paired-breast cancer tissues by PCR analysis. The results revealed that SIK3 mRNA expression was significantly higher in tumor tissues when compared to the normal adjacent tissues (73.25 times, n=183). Thus, it is proposed for the first time that the antitumor effect induced by curcumin …

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Anti-Lymphangiogenic Diterpenes From The Bark Of Calocedrus Macrolepis Var. Formosana, Tzong-Huei Lee, Chin-Lin Hsieh, Ho-Cheng Wu, Shih-Wei Wang, Chen-Lin Yu, George Hsiao, Ming-Jen Cheng, Wen-Tsong Hsieh, Yueh-Hsiung Kuo Dec 2021

Anti-Lymphangiogenic Diterpenes From The Bark Of Calocedrus Macrolepis Var. Formosana, Tzong-Huei Lee, Chin-Lin Hsieh, Ho-Cheng Wu, Shih-Wei Wang, Chen-Lin Yu, George Hsiao, Ming-Jen Cheng, Wen-Tsong Hsieh, Yueh-Hsiung Kuo

Journal of Food and Drug Analysis

Eight new diterpenes, 6α,7β-dihydroxyferruginol (1), 6α,7α-dihydroxyferruginol (2), 6α-hydroxyhinokiol (3), 4α-hydroxy-7-oxo-18-norabieta-8,11,13-trien-4α-ol (4a), 15,16-dehydrosugiol (5), 7-methoxy-6,7-secoabieta-8,11,13-triene-6,12-diol (6), 7α-acetoxyabieta-8,12-diene-11,14-dione (7), 7α-butyloxyethyloxyabieta-8,12-diene-11,14-dione (8), along with four known compounds, 6,7-dehydroferruginol (9), 12-hydroxy-6,7-secoabieta-8,11,13-triene-6,7-dial (10), 7α-11-dihydroxy-12-methoxy-8,11,13-abietatriene (11), and 11,14-dihydroxy-8,11,13-abietatrien-7-one (12) were successfully isolated from the bark of Calocedrus macrolepis var. formosana. The structures of all isolates were elucidated by physical data (appearance, UV, IR, optical rotation) and spectroscopic data (1D, 2D NMR, and HREIMS). Compounds 9, 10, 11, and 12 showed promising growth-inhibitory effect on human lymphatic endothelial cells (LECs). Among these compounds, compound 10 exerted the most potent anti-lymphangiogenesis property by suppressing cell growth and …

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Medicarpin Isolated From Radix Hedysari Ameliorates Brain Injury In A Murine Model Of Cerebral Ischemia, Chang-Ming Chern, Chung-Kuang Lu, Kuo-Tong Liou, Yea-Hwey Wang, Keng-Chang Tsai, Chia-Lin Chang, Chia-Che Chang, Yuh-Chiang Shen Dec 2021

Medicarpin Isolated From Radix Hedysari Ameliorates Brain Injury In A Murine Model Of Cerebral Ischemia, Chang-Ming Chern, Chung-Kuang Lu, Kuo-Tong Liou, Yea-Hwey Wang, Keng-Chang Tsai, Chia-Lin Chang, Chia-Che Chang, Yuh-Chiang Shen

Journal of Food and Drug Analysis

The development of effective post-stroke therapy is highly demanded. Medicarpin is a key active component of a famous Chinese herbal prescription used for post-stroke treatment in Taiwan; however, little is known about its biological effects and mechanisms of action. Herein, we implemented a murine model of cerebral ischemic/reperfusional injury-related stroke to elucidate medicarpin’s neuroprotective effect. In male ICR mice 24 h after stroke induction, treatment with medicarpin (0.5 and 1.0 mg/kg, i.v.) markedly enhanced the survival rates, improved moving distance and walking area coverage, reduced brain infarction, and preserved the blood-brain barrier, supporting medicarpin’s protective effect on stroke-induced injury. Immunohistochemistry …

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In-Silico Efficacy Of Potential Phytomolecules From Ayurvedic Herbs As An Adjuvant Therapy In Management Of Covid-19, Bhanu Kumar, Ankita Misra, Satyendra Pratap Singh, Yogeshwar Vikram Dhar, Poonam Rawat, Debprasad Chattopadhyay, Saroj Kanta Barik, Sharad Srivastava Dec 2021

In-Silico Efficacy Of Potential Phytomolecules From Ayurvedic Herbs As An Adjuvant Therapy In Management Of Covid-19, Bhanu Kumar, Ankita Misra, Satyendra Pratap Singh, Yogeshwar Vikram Dhar, Poonam Rawat, Debprasad Chattopadhyay, Saroj Kanta Barik, Sharad Srivastava

Journal of Food and Drug Analysis

The recent COVID-19 outbreak caused by SARS-CoV-2 virus has sparked a new spectrum of investigations, research and studies in multifarious directions. Efforts are being made around the world for discovery of effective vaccines/drugs against COVID-19. In this context, Ayurveda, an alternative traditional system of medicine in India may work as an adjuvant therapy in compromised patients. We selected 40 herbal leads on the basis of their traditional applications. The phytomolecules from these leads were further screened through in-silico molecular docking against two main targets of SARS-CoV-2 i.e. the spike protein (S; structural protein) and the main protease (MPRO …

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Conducting Polymer-Based Sensors For Food And Drug Analysis, Chia-Hsin Lin, Jia-Hui Lin, Chien-Fu Chen, Yoshihiro Ito, Shyh-Chyang Luo Dec 2021

Conducting Polymer-Based Sensors For Food And Drug Analysis, Chia-Hsin Lin, Jia-Hui Lin, Chien-Fu Chen, Yoshihiro Ito, Shyh-Chyang Luo

Journal of Food and Drug Analysis

Conducting polymers (CPs) are a category of polymeric materials with conjugated main chains. The characteristic electrical and optical properties of CPs can be fine-tuned through controlling the doping states of CPs. Because of their long-term stability in water, CPs have been demonstrated as electroactive biointerfaces and electrode materials especially in aqueous environments. Serving as multifunctional interfaces and organic electrodes for the integration bioelectronics and devices, CPs have been studied and applied in various biological applications. This paper provides a review of conducting polymer–based electrochemical sensors, particularly those used in biological fields. General conducting polymers and derivatives and their main electrochemical …

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Recent Developments In Sensing Of Oversulfated Chondroitin Sulfate In Heparin. A Review ., Manivannan Madhu, Wei-Lung Tseng Dec 2021

Recent Developments In Sensing Of Oversulfated Chondroitin Sulfate In Heparin. A Review ., Manivannan Madhu, Wei-Lung Tseng

Journal of Food and Drug Analysis

Oversulfated chondroitin sulfate (OSCS), a non-natural sulfated glycosaminoglycan, recognizes as a significant containment in the pharmaceutical heparin, and it could trigger adverse reactions. Chromatography-, electrophoresis-, electrochemistry-, and spectroscopy-related techniques are currently available for accurate and precise analysis of a trace amount of OSCS in heparin. Recently, emerging studies focus on developing colorimetric and fluorescent probes to monitor OSCS containments in heparin. Therefore, this current review aims to describe the sensing principle and procedure of the reported probes that are sensitive and selective toward OSCS in heparin without the interferences of other sulfated glycosaminoglycans. The reported OSCS-specific probes are comprehensively discussed …

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Florida History In Periodicals, 1983, Florida Historical Society Dec 2021

Florida History In Periodicals, 1983, Florida Historical Society

Florida Historical Quarterly

This selected bibliography includes scholarly articles in the fields of Florida history, archeology, geography, and anthropology published in state, regional, and national periodicals in 1983. Articles, notes, and documents which have appeared in the Florida Historical Quarterly are NOT included in this listing since they appear in the annual index of each volume. The present listing also includes articles appearing in journals not published on schedule and which were not included in the list published in the July 1983 issue of the Quarterly.

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Teaching And Assessing College Stem Courses Online During Covid-19: Evidence-Based Strategies And Recommendations, Santanu De, Georgina Arguello Dec 2021

Teaching And Assessing College Stem Courses Online During Covid-19: Evidence-Based Strategies And Recommendations, Santanu De, Georgina Arguello

FDLA Journal

Since the devastating COVID-19 pandemic, most schools, colleges, and universities worldwide underwent a paradigm shift by transitioning to digital teaching and learning modalities. This phenomenon was essential to mitigate the contagion; however, the academic institutions needed to quickly come up with ways to ensure that the quality and rigor of education were maintained, especially the active and experiential learning required by undergraduate and graduate courses in science, technology, engineering, and mathematics (STEM). This paper highlights key approaches reported or proposed to effectively conduct college-level, in-person STEM courses online owing to the pandemic. These would range from synchronous versus asynchronous pedagogies …

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Philosophical Foundations Of African Women's Indigenous Knowledge For Food Security: Towards Narrative Feminist Pedagogy, Humphrey Jeremiah Ojwang, Wanjiku Mukabi Kabira, Penninah Amolo Ogada Dec 2021

Philosophical Foundations Of African Women's Indigenous Knowledge For Food Security: Towards Narrative Feminist Pedagogy, Humphrey Jeremiah Ojwang, Wanjiku Mukabi Kabira, Penninah Amolo Ogada

FDLA Journal

This paper explores the pedagogical value of African Women’s Indigenous Knowledge or Food Security. The approach is narratological and takes into account oral testimonies and life-stories of women farmers in Homa Bay County, Kenya. The paper proposes African feminist epistemology as a viable approach in the pedagogy of food security and agricultural extension in rural Kenya. This is a paradigm shift which incorporates women farmers’ indigenous knowledge in formal agricultural education and extension programmes. The paradigm shift to African feminist epistemology is a response to a pedagogical anomaly where women’s indigenous knowledge has been relegated to the sidelines, with hegemonic …

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University Curriculum Committee Meeting Minutes - December 14, 2021, University Curriculum Committee Dec 2021

University Curriculum Committee Meeting Minutes - December 14, 2021, University Curriculum Committee

University Curriculum Committee Meeting Materials

Minutes for the Governors State University Curriculum Committee Meeting held December 14, 2021.

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Fall Commencement Program, December 14, 2021, Coastal Carolina University Dec 2021

Fall Commencement Program, December 14, 2021, Coastal Carolina University

Commencement Programs

Program of Commencement Exercises at Coastal Carolina University.

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Citric Acid/Β-Alanine Carbon Dots As A Novel Tool For Delivery Of Plasmid Dna Into E. Coli Cells, Anju Pandey, Asmita Devkota, Anil Sigdel, Zeinab Yadegari, C. Korsi Dumenyo, Ali Taheri Dec 2021

Citric Acid/Β-Alanine Carbon Dots As A Novel Tool For Delivery Of Plasmid Dna Into E. Coli Cells, Anju Pandey, Asmita Devkota, Anil Sigdel, Zeinab Yadegari, C. Korsi Dumenyo, Ali Taheri

Agricultural and Environmental Sciences Faculty Research

Successful delivery of plasmid DNA into the microbial cells is fundamental in recombinant DNA technology. Natural bacterial transformation is limited to only certain species due in part to the repulsive forces between negatively charged DNA and bacterial membranes. Most common method of DNA delivery into bacteria is artificial transformation through heat shock and electroporation. These methods require sophisticated instruments and tedious steps in preparation of competent cells. Transformation by conjugation is also not applicable to all plasmids. Nanoparticles have been used successfully in therapeutics for drug delivery into animal cells. They are starting to gain popularity in plant sciences as …

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University Curriculum Committee Meeting Minutes - December 14, 2021, University Curriculum Committee Dec 2021

University Curriculum Committee Meeting Minutes - December 14, 2021, University Curriculum Committee

Faculty Senate Minutes

Minutes for the Governors State University Curriculum Committee Meeting held December 9, 2021

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Single-Cell Rna Sequencing (Scrna-Seq) Exploratory Analyses To Investigate Aging-Dependent Changes And Regional Heterogeneity In Glial Cells, Valerie N. Doze Dec 2021

Single-Cell Rna Sequencing (Scrna-Seq) Exploratory Analyses To Investigate Aging-Dependent Changes And Regional Heterogeneity In Glial Cells, Valerie N. Doze

CSB and SJU Distinguished Thesis

My thesis project research consisted of single-cell RNA-sequencing and bioinformatics using R programming and Neuroscience Multi-omic Data Archive (NeMO) Analytics to examine the impact of aging, brain region, and other variables on the genotypes and phenotypes of oligodendrocytes (OLGs) and oligodendrocyte precursor cells (OPCs). The overarching goal was to increase understanding of glial cell fate and function. After determining bioinformatical findings, follow-up wet-bench experiments were performed to validate results. RNA in situ hybridization and immunohistochemistry were performed to confirm differential gene expression across cell types and brain regions. These experiments also revealed any changes in oligodendrocyte (OLG) development and maturation …

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Incarcerated People With Co-Occurring Disorders, Nikki Ketzeback Dec 2021

Incarcerated People With Co-Occurring Disorders, Nikki Ketzeback

Counselor Education Capstones

People with mental illnesses are at a significantly greater risk of police arrest than the general population. This pattern of arrests has been associated with a phenomenon referred to as the criminalization of mental illness. The influence of mental health and the criminal justice system will be discussed throughout this paper. The research discussed within this paper serves as a framework for the development of a co-occurring curriculum. The curriculum developed includes components related to the overall goal of criminal justice (reducing recidivism) while addressing mental health components within a therapeutic group setting. The focus of the curriculum attached is …

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