Digital Commons Network^™

Restoring The Wild East: Predicting Public Support For Cougar And Red Wolf Reintroduction In The Eastern United States, Benjamin Ghasemi, Jeremy T. Bruskotter, John A. Vucetich, L. Mark Elbroch, Robyn S. Wilson, Neil H. Carter, Axel Moehrenschlager, Shelby Perry, Joseph W. Hinton

Michigan Tech Publications

Restoring large carnivores to human-dominated landscapes remains ecologically and socially contentious, though reintroduction may offer important benefits where coexistence is possible. Yet, efforts to reintroduce cougars (Puma concolor) and red wolves (Canis rufus) in the Eastern U.S. face major challenges, largely due to human-caused mortality and opposition. We employed the hazard acceptance model and structural equation modeling to investigate the socio-psychological drivers of public support for reintroduction. Survey data were collected from residents of the Eastern U.S. for cougars (n = 2665) and red wolves (n = 3825). For both species, support was positively associated with perceived personal and societal …

Machine Learning Classification Of Prostate Cancer Genomic Sequences Using K-Mer And Sequence-Derived Features, Kuldeep Rawat, Hirendra Nath Banerjee, Jamie Noble, Saa Naudia Deloatch, Satyendra Banerjee, Sachin Shetty, Soumya Banerjee

VMASC Publications

Prostate cancer disproportionately impacts African American men, who experience significantly higher mortality rates and earlier disease onset than other populations. Current diagnostic approaches, including prostate-specific antigen testing and biopsy, lack sufficient specificity and sensitivity, underscoring the need for accurate, molecular-level classification tools. This paper presents a machine learning framework for binary classification of genomic DNA sequences as cancerous or healthy. A dataset of 1684 FASTA-formatted sequences obtained from the National Library of Medicine - GenBank was analyzed, with 1662 sequences retained after quality control filtering. Feature engineering yielded 67 attributes, including GC content, Shannon entropy, sequence length, and trinucleotide k-mer …

Different Destinations: Clarifying And Addressing Pipeline Problems For Women In Academic Archaeology, Scott R. Hutson, Jaycee Castro, Bruno Athie Teruel

Anthropology Faculty Publications

In STEM fields, women tend to leak out of the pipeline to the professoriate. In archaeology, however, robust databases and chronological control reveal that there is no leakage from earning a PhD to tenure-track positions. Nor is there a leak from assistant professor to associate professor. Nevertheless, men get hired as faculty in PhD programs more often than women. This is important because PhD programs are research-intensive and train future leaders. Furthermore, women PhD students have women as advisers more than often men and report advantages to this arrangement. Yet with fewer women faculty in PhD programs, women mentors are …

A Neo-Kuyperian Approach To Mathematics, Calvin Jongsma, Kevin Vander Meulen

Faculty Work Comprehensive List

This chapter develops a Reformational perspective on the discipline of mathematics that stems from the seminal ideas of Kuyper, Dooyeweerd, Wolters, Clouser, and others. The implications of the Biblical motif of Creation-Fall-Redemption is explored for the task of Christian scholarship in general and for the field of mathematics in particular, drawing upon relevant developments in the history and philosophy of mathematics.

Genes For Sale!, Anya E.R. Prince

Emory Law Journal

In March 2025, 23andMe, the flagship direct-to-consumer (DTC) genetic testing company, filed for bankruptcy. Just like that, the genetic information of fifteen million customers was up for sale to the highest bidder, creating a firestorm of reactions from the public, media, state attorneys general, and legislators warning of the dire outcomes that could arise from the sale of such sensitive data. The warnings seemed reasonable, as federal law does little to protect consumers from the widespread sale and misuse of their genetic data.

Yet, in retrospect, the public concerns and media frenzy could potentially be seen as excessive given the …

Unlikely Criminals: Inside The Ivf Drug Grey Market, Maybell Romero

Emory Law Journal

In this Article, I admit to committing crimes, specifically buying fertility drugs on the in vitro fertilization (IVF) drug grey market. Drawing from personal experience, I explore how people wanting to undergo IVF turn to the criminalized fertility drug grey market to access necessary but prohibitively expensive fertility medications that would otherwise be out of reach. In the absence of comprehensive insurance coverage, patients often rely on informal online communities to obtain medications at lower prices, often from other patients whose IVF cycles have been canceled or who have excess drugs. While these transactions fulfill a critical need, they also …

Making Environmental Cancer Risk Legally Visible: Legal Epidemiology, Chemical Regulation, And The Failures Of Cancer Cluster Investigations, Beverley C. Thompson

Emory Law Journal

Environmental cancer risks remain difficult to detect, investigate, and remediate despite decades of federal regulation under the Toxic Substances Control Act (TSCA). Cancer cluster investigations are designed to identify unusual patterns of cancer and their environmental causes, but fragmented authority, inconsistent methodologies, and narrow investigative frameworks routinely prevent these investigations from addressing population-level harms. By failing to detect and address cancer clusters, public health systems inadvertently perpetuate environmental injustices, disproportionately harming communities already underserved and overburdened by pollution.

These failures are not merely scientific but reflect legal and institutional design choices that determine which cancer risks are visible, investigable, and …

Complex Interplay Between Facilitation And Competition In Two Invasive Fruit Pests, Eleanor Mccabe, Nicholas M. Teets

Entomology Faculty Publications

When one invasive species facilitates the invasion of another species, it can lead to invasional meltdown. However, when the two species depend on the same finite resource, facilitation and competition can occur simultaneously and impact population dynamics. Furthermore, factors like resource availability and population density could alter the balance between facilitation and competition. Drosophila suzukii and Zaprionus indianus are two invasive insect pests that infest small fruit crops. The co-localization of these species in the same fields, coupled with the fact that Z. indianus lacks a hardened ovipositor that can penetrate the skin of fruit, has led to the hypothesis …

Elevated Temperatures Disrupt Wolbachia-Induced Feminisation And Reshape Microbial Community Dynamics Across Generations In A Spider Host, Virginija Mackevicius-Dubickaja, Jennifer A. White, Ellen E. Williams, Eyal Klement, Yuval Gottlieb, Matthew R. Doremus

Entomology Faculty Publications

Longitudinal microbial interactions within a host are challenging to study, leading to a focus on constructed microbial communities in vitro settings. Here, we take advantage of a naturally defined microbial community within a spider host to study how elevated temperatures influence microbial dynamics and phenotypes across host generations. The spider Mermessus fradeorum hosts up to five endosymbionts, including a Wolbachia strain, W1, which induces feminisation, causing genetic males to develop as phenotypic females, skewing sex ratios and promoting symbiont spread. Despite this, Wolbachia 1 persists at intermediate frequencies in wild populations. We hypothesised that elevated temperatures might reduce penetration of …

Evolutionary Transitions In Social Behavior Are Associated With Convergent And Partially Reversible Expansions Of Transcription Factor Binding Sites, Savanna G. Ploessl, Beryl M. Jones

Entomology Faculty Publications

The evolution of sociality involves shifts in physiology and behavior, most notably the emergence of a reproductive division of labor. Within social colonies, these distinct behavioral phenotypes arise from differential regulation of a shared genome. Changes in transcription factor (TF) binding motifs are one potential mechanism underpinning this plasticity, with prior studies suggesting that social species exhibit expansions in TF binding sites. However, it remains unclear whether motif expansions are reversed when sociality is lost. Here we analyze predicted TF motif occurrences across gene promoters in 42 bee species spanning millions of years of evolutionary divergence and multiple independent gains …

Variability In Mountain Pine Beetle (Coleoptera: Curculionidae) Gene Expression In Response To Increasing Concentrations Of Species-Specific Double-Stranded Rna, Kylie J. Bickler, Zachary Bragg, Flávia Pampolini, Bethany R. Kyre, Lynne K. Rieske

Entomology Faculty Publications

Sensitivity to double-stranded RNA (dsRNA)-induced gene silencing has been observed in multiple coleopterans. Initial work with mountain pine beetle, Dendroctonus ponderosae Hopkins, determined that specific ubiquitously expressed essential genes can cause mortality when silenced by carefully designed dsRNAs. However, current dsRNA production methods are not economically feasible for production at scale. Therefore, identifying the minimum efficacious dose is a critical step to deployment. To investigate the relationship between dsRNA dose and subsequent gene expression, adult mountain pine beetles were fed either a target or control dsRNA across a gradient of concentrations, including 2.5, 1.0, 0.25, and 0.025µg/µl, and relative gene …

Schelling & Spinoza, Michael Vater

Philosophy Faculty Research and Publications

Schelling is notorious for having a fluid vision of systematic philosophy and its methods. In an age where philosophy is expected to result in one or two books, not years of discussions with students and colleagues--and certainly not a distillation of one’s way of life--Schelling’s thought has been called protean or restless, or in Hegel’s snarky verdict “an education pursued in public.” The same could be said of Socrates. But there is a truth in these comments; it is difficult to find in fifty-six years of publications, addresses and abandoned manuscripts the single argument that is Schelling’s philosophy. What provokes …

The Rna-Binding Protein Hur Modulates The Expression Of The Disease-Linked Ccl2 Rs1024611g-Rs13900t Haplotype, Feroz Akhtar, Joselin Hernandez-Ruiz, Ya-Guang Liu, Roy G. Resendez, Denis Feliers, Liza D. Morales, Alvaro Diaz-Badillo, Donna M. Lehman, Rector Arya, Juan Carlos Lopez-Alvarenga, John Blangero, Ravi Duggirala, Srinivas Mummidi

School of Medicine Publications

CC-chemokine ligand 2 (CCL2) is involved in the pathogenesis of several diseases associated with monocyte/macrophage recruitment, such as HIV-associated neurocognitive disorder (HAND), tuberculosis, and atherosclerosis. The rs1024611 (alleles: A>G; G is the risk allele) polymorphism in the CCL2 cis-regulatory region is associated with increased CCL2 expression in vitro and ex vivo, leukocyte mobilization in vivo, and deleterious disease outcomes. However, the molecular basis for the rs1024611-associated differential CCL2 expression remains poorly characterized. It is conceivable that genetic variant(s) in linkage disequilibrium (LD) with rs1024611 could mediate such effects. Previously, we used rs13900 (alleles: C>T) in the CCL2 …

Associations Of Blood Pressure Level And Variability With Cortical Thickness: A Cross-Sectional Analysis From The Maracaibo Aging Study, Romeo De Leon, Shana Garza, Silvia Mejia-Arango, Kristina Vatcheva, Sokratis Charisis, Claudia L. Satizabal, Luis J. Mena, Joseph H. Lee, Joseph D. Terwilliger, Eron Manusov

School of Medicine Publications

Background: Although high blood pressure (BP) level and variability are associated with Alzheimer's Disease (AD), their relationship with cortical thickness in brain regions that are associated with AD is unclear. Furthermore, the role of 24-hour BP has not been examined. We investigated the associations of office and ambulatory BP measures with cortical thickness in brain regions implicated in AD.

Methods: We performed a cross sectional analysis of 304 participants without dementia from a population-based study with office and 24-hour BP and magnetic resonance imaging (MRI) data. We considered cortical thickness values derived from 10 regions throughout the frontal, parietal, and …

Reduced Threat-Related Neural Efficiency: A Possible Biomarker For Pediatric Anxiety Disorders, Julia O. Linke, Reut Naim, Simona P. Haller, Parmis Khosravi, Beck Scheinberg, Meghan E. Byrne, Anita Harrewijn, Ellen Leibenluft, Melissa A. Brotman, Anderson M. Winkler, Daniel Samuel Pine

School of Medicine Publications

Objective: Pediatric anxiety disorders are common and predict adult psychopathology, yet current treatments, such as cognitive-behavioral therapy (CBT), produce lasting remission in less than 50% of affected youths. To support the search for improved, mechanistically grounded interventions, this study evaluated neural efficiency, defined as similarity in functional connectivity between a threat task and rest, as a potential biomarker. The study evaluated neural efficiency in relation to anxiety diagnosis and treatment response.

Methods: The authors compared 103 youths with an anxiety disorder diagnosis (mean age, 12.5 years [SD=2.91], 62% female) to 103 youths with no psychiatric diagnosis (mean age, 13.4 years …

Breaking The Resistance: A Narrative Review Of The Evolution From Traditional Drugs To Precision Therapies In Epilepsy, Tirath Patel, Fathimathul Henna, Ashfaq Ahmed, Ayesha Ahmad, Noor Ul Huda, Syed Aaraiz Ul Hassan, Aiman Muhammad, Amna Javed, Maryem Filal, Nikhilesh Anand

School of Medicine Publications

Background: Epilepsy is a chronic neurological disorder characterized by recurrent seizures, affecting approximately 50 million individuals globally. While conventional antiseizure medications (ASMs) control seizures in 70-80% of patients, about 30% experience drug resistance or intolerable side effects, necessitating alternative approaches.

Objective: To critically compare the efficacy, safety, and accessibility of conventional and emerging therapies for epilepsy, particularly in the context of treatment-resistant cases and global disparities in care.

Methods: This narrative review synthesized evidence from 120 peer-reviewed articles published between 2015 and 2025. Literature was retrieved from PubMed, Embase, Cochrane Library, and Scopus using predefined search terms related to epilepsy …

Early Detection In Oral Cancer: Are We Prepared For Artificial Intelligence-Driven Precision Medicine?, Nikil Kumar, Sinnha Kumari, Sadia Sultana, Muhammad Saad Khan, Tirath Patel, Nikhilesh Anand

School of Medicine Publications

Oral cancer, particularly oral squamous cell carcinoma, remains a serious health concern, with a poor prognosis and a late diagnosis. Leukoplakia, erythroplakia, lichen planus, and submucous fibrosis are examples of oral potentially malignant disorders that must be detected early but are not always so by traditional, laborious, and subjective diagnostic techniques. In oral cancer, artificial intelligence (AI) and precision medicine are becoming game-changing technologies that enhance individualized care, treatment planning, and diagnostic precision. Complex imaging and histopathology data may be analyzed using machine learning and deep learning algorithms, particularly convolutional neural networks, which can identify patterns that are invisible to …

Hall Current And Nth Order Chemical Reaction Effects On Unsteady 3d Mhd Williamson Nanofluid Flow With Thermophoresis And Brownian Motion Over An Inclined Stretching Sheet, Polavarapu Sudheer, Ramachandra Reddy Vaddemani, Raghunath Kodi

Mansoura Engineering Journal

This study examines the influence of Hall current and nth-order chemical reaction on unsteady three-dimensional magnetohydrodynamic (MHD) Williamson nanofluid flow over an inclined stretching sheet. The model incorporates thermal radiation, heat source, Brownian motion, and thermophoresis effects. The governing nonlinear partial differential equations are transformed into a system of ordinary differential equations using similarity transformations and solved numerically using the shooting method with a fourth-order Runge–Kutta scheme. The results indicate that an increase in the magnetic parameter significantly reduces velocity profiles while enhancing temperature and concentration distributions. The Hall parameter reduces surface drag and improves heat transfer, while decreasing mass …

Optimization Of Mechanical Properties Of Copper Nanofiller Reinforced Banana Fiber Polyester Composites Using Grey–Taguchi Method, Nikhil Janardan Rathod, Mayur Jayant Gitay, Markala Karthik, Harshwardhan Ghongade, Upendra Rajak, Rajendra Sopan Narkhede

Mansoura Engineering Journal

Mechanical performance of banana fiber-reinforced polyester composites maximized using a composite Taguchi and a Grey Relational Analysis (GRA) process. This will aim at enhancing dispensation limits to enhance better tensile, flexural and impact belongings. The hand lay-up method was used to create composites by variable three key limits and they included banana fiber content (30 wt%), copper nanoparticle content (15 wt%), and curing temperature (80 o C). Trial design and mechanical properties were being measured in form of ASTM values on a L9 orthogonal array.

The multi-response optimization was performed with the help of the Grey Relational Analysis, which was …

An Iterative & Analytical Hybrid Deep Learning Framework For Enhanced Brain Tumor Detection And Segmentation In Mri Video Scans, Swati V. Sakhare

Mansoura Engineering Journal

The critical need for accurate and robust brain tumor detection in MRI video scans is for early diagnosis and treatment planning operations. However, the existing methods suffer from several limitations, such as not being able to capture spatio-temporal features, handling class imbalances, and generalizing across datasets with diverse characteristics. To address these challenges, I propose a hybrid deep learning framework that integrates multiple advanced techniques to enhance the detection and segmentation of brain tumors. My approach starts by using the 3D CNN-LSTM (ResNet3D-LSTM) to extract spatio-temporal feature, which utilizes ResNet3D for spatial detail extraction and LSTM for temporal coherence across …

Trident-Bladder: A Resolution-Aware Multimodal System For Robust, Calibrated Bladder Cancer Diagnosis Across Endoscopy, Histopathology, And Liquid Biopsy, K. Sankar, S. Venkata Lakshmi, Gummadi Reshma, V. Gokula Krishnan, M. Ganesan, V. Vijayaraja

Mansoura Engineering Journal

Bladder cancer diagnosis demands the integration of cystoscopy, histopathology, and biomarker testing, yet the majority of AI systems continue to be modality, specific and sensitive to acquisition variations. TRIDENT, Bladder is a resolution, aware multimodal framework that we have developed to address this issue. The method combines cystoscopic lesion segmentation, whole, slide image (WSI) molecular subtype prediction, and urine miRNAclinical data through reliability, weighted fusion and a utility, aware decision policy. The endoscopic branch features a quality, gated super, resolution component, resulting in mDice 87.5, sensitivity 92.1%, precision 91.4%, boundary, F1 85.3%, and ECE 0.023 at 32 FPS. mDice on …

Application Of Current Enteral Nutrition Support Recommendations To Infants Born Less Than 750 Grams Or Less Than 25 Weeks' Gestation: A Critical Review, Mar Romero-Lopez, Mamta Naik, Teresa Hartman, Ann Anderson-Berry, Melissa Thoene

Journal Articles: Pediatrics

Clinicians face a paucity of evidence-based recommendations for provision of enteral nutrition in infants born < 750 g or < 25 weeks' gestation, termed "nano-preterm." Current enteral nutrition recommendations for extremely low birth weight infants may not be broadly applicable to nano-preterm infants due to physiological and developmental differences, while others may be appropriate. Key enteral nutrition-related considerations include: the unique anatomy and physiology of the gastrointestinal tract, altered metabolic capacity, availability of maternal milk and use of alternative substrates, detailed methods of initiation and advancement of enteral feeding, methods of human milk fortification, targeted requirements for macronutrient and micronutrients, and the safety and efficacy of enteral nutrition support management to optimize the growth and development of the nano-preterm infant. This comprehensive review focused on enteral nutrition provision in nano-preterm infants, thoroughly evaluating available literature and identifying knowledge gaps about the unique physiology and metabolism of the nano-preterm infant as it pertains to enteral nutrition. Ultimately, prospective multicenter research is needed to establish evidence-based guidelines to promote optimal growth and development while minimizing complications of extreme prematurity.

Frequency Ranking Of Imaging Biomarkers For Lung Cancer Risk Stratification Using A Hybrid Elastic Net Method, Mohamed Jaber, Emmy Stevens, Nezamoddin N. Kachouie

Mathematics and System Engineering Faculty Publications

Lung cancer remains the leading cause of cancer-related mortality worldwide, emphasizing the critical need for novel and robust biomarkers to improve prognostication and guide precision oncology. While traditional clinical variables such as tumor stage, age, and sex are routinely used for survival prediction, their prognostic performance is limited. Imaging biomarkers derived from radiomic analysis of advanced medical imaging have emerged as a promising class of noninvasive cancer biomarkers, enabling quantitative characterization of tumor phenotypes. In this study, we investigated the prognostic utility of radiomic imaging biomarkers, with a particular focus on the texture-based feature Busyness, and compared their performance against …

The Loss Of Symbolic Imagination And The Decline Of Christian Practice: A Blondelian Perspective, Cathal Doherty

Theology Faculty Research and Publications

The contemporary decline in Christian church-going and sacramental participation is due in part to the legacy of the Enlightenment, which valorizes the life of the mind over actual practice, a distortion due to a conceptualism of human action, widespread in Western thought, that sees in human action the mere execution of ideas. From here, it is a short step to the willful blindness that restricts our action to the execution of exclusively human ideas and concepts, to the exclusion of the divine, quietly repudiating the claims of orthodox Christian revelation that the divine intention is symbolically realized for us in …

The Underappreciated Role Of Rifampin In Shaping The Epidemiology Of Rt027-Like Clostridioides Difficile Lineages, Isabella A. Tickler, Richard V. Goering, Fred Tenover

Biology Faculty Publications

The global emergence and dissemination of epidemic Clostridioides difficile ribotype 027 (RT027) and related lineages illustrate the role of antimicrobial pressure in shaping the epidemiology of this pathogen. We propose a hierarchical model in which fluoroquinolones (FQs) served as the dominant selective force underlying the worldwide expansion of RT027-related strains, with rifampin and rifamycins acting as secondary modifiers that promoted persistence and regional dominance. ©

Niche Partitioning Between Myrtle And Audubon's Warblers, Aidan Brubaker

IdeaFest 2026

Do Audubon's and myrtle yellow-rumped warblers partition resources differently in areas where the two subspecies overlap during the winter in Arcata, California? Looking for differences in the foraging height, foraging substrate, horizontal foraging location, and foraging methods of the two subspecies.

Large Language Model-Based Automated Item Generation In Stem Assessments: Historical Mapping And A Scoping Review Of Empirical Studies, Moses Oluoke Omopekunola

Journal of Educational Technology Development and Exchange (JETDE)

Educational assessments, from low-stakes classroom tests to high-stakes national examinations, require item pools that are valid, fair, and secure. Automated Item Generation (AIG) aims to efficiently produce large pools of calibrated test items. This paper adopts a two-part design: (1) a brief historical mapping situating LLM-based AIG within the broader AIG trajectory; and (2) a scoping review of empirical studies on LLM-based AIG for STEM assessments, published between January 2022 and January 2026. A structured search of ERIC, Lens and OpenAlex yielded 1,267 records; after deduplication and screening, 7 studies were retained for synthesis. In all studies, LLMs were primarily …

A Hierarchical And Multidimensional Approach To Profiling Students’ Digital Skills In Educational Technology, Emil S. Frashëri, Eleni F. Vangjeli

Journal of Educational Technology Development and Exchange (JETDE)

This study investigates university students’ digital competence through a multidimensional and person‑centered analytical framework grounded in bifactor–Exploratory Structural Equation Modeling (B‑ESEM). Digital competence was conceptualized across four functional skill domains and a general competence factor, reflecting contemporary perspectives on technology‑enhanced learning and student readiness. To overcome a common limitation in traditional Latent Profile Analysis (LPA), the conflation of overall competence levels with relative skill configurations, this study employed B‑ESEM–derived factor scores to preserve both hierarchical structure and multidimensionality. Using data from 599 university students, a four‑profile solution emerged, capturing distinct patterns of digital skill strengths and weaknesses. Gender and programming …

Virtual Nature-Exposure And Slow Breathing Interactive Effect On Stress, Mari Sanchez, J.P. Benefiel, J. Linder, S. Rawitch, Z. Poer, P. Spoor

IdeaFest 2026

Excess stress negatively impacts health and well-being. The current study examined two accessible research-based methods of stress reduction: virtual nature exposure and slow breathing. Participants completed a stressful task and were then exposed to either a scene of nature or a grey control screen while breathing slowly or regularly (control). Physiological measures of stress were compared across groups. Results reaffirm slow breathing as beneficial for stress reduction. Virtual nature exposure did not impact stress levels independently and did not interact or add to the stress reducing impacts of slow breathing.

Postfire Habitat Use And Density Of Pacific Martens (Martes Caurina) In Lassen National Forest, California, Deirdre L. Replinger

Cal Poly Humboldt theses and projects

Increasing frequency, size, and severity of wildfires in western North America threatens forest-dependent wildlife species. The Pacific marten (Martes caurina) has historically been associated with mature, structurally complex forest throughout most of its range. Recently, martens have been detected in forests burned at high severity by the 2021 Dixie Fire—the largest recorded single fire in California state history. I used non-invasive remote camera traps and hair snares (n = 166 sites) to assess marten habitat use and density using spatial occupancy and spatial capture-recapture models. I detected martens across the burn severity gradient (unburned to high-severity) at …