Digital Commons Network^™

Adipose Tissue-Derived Small Extracellular Vesicles In Plasma Reveal Molecular Circuitries Underlying Glucose Intolerance, Shalini Mishra, Yixin Su, Ashish Kumar, Sangeeta Singh, Brian S. Finlin, Fang-Chi Hsu, Jingyun Lee, Cristina M. Furdui, Philip A. Kern, Swapan K. Das, Gagan Deep

Internal Medicine Faculty Publications

Objective: Glucose tolerance (GT) is a major effector for adipose tissue (AT) remodeling in obesity, yet its molecular mechanisms remain incompletely defined. We hypothesized that the biophysical and molecular profiles of AT-derived small extracellular vesicles (sEV^AT) change in response to glucose availability and differ by GT status.

Methods: sEV^AT were isolated from plasma of individuals with normal GT (NGT) and impaired GT (IGT) (n = 5/group) at fasting (0 h) and 1 h post glucose challenge during oral glucose tolerance test (OGTT). sEV^AT were characterized for size, concentration, surface expression of insulin receptor-α (INSRα), proteome, …

Review Of Bioethics: A Coursebook, Ian Werkheiser

Open Educational Resources - Reviews

No abstract provided.

How The Proposed Esa Habitat Rule Harms Species On Public Lands, Sandi Zellmer

Faculty Journal Articles & Other Writings

At present, there are 1,684 federally listed endangered and threatened species in the United States. Habitat modification is the primary reason for listing. The U.S. Fish and Wildlife Service (FWS) and the National Oceanic and Atmospheric Administration (NOAA) have proposed a rule that would rescind their decades-old definition of “harm” under the Endangered Species Act (ESA). Currently, “harm” is the only term within ESA Section 9’s prohibition on “take” that encompasses habitat modification. If modifying habitat is no longer a “take,” the ESA itself would be rendered incapable of satisfying Congress’s goal: “to halt and reverse the trend toward species …

Student Wellness: Exploring The Role Of Faculty In Implementing Effective Supports For Mental Well-Being And Academic Performance In Community College Dental Hygiene Education, Bernadette Heather Smith

Dissertations

Purpose: The purpose of this phenomenological, comparative study was to identify and describe effective supports used by dental hygiene faculty and their role in the mental well-being and academic performance of community college dental hygiene students.

Methodology: Two Southern California community college dental hygiene programs were selected for this phenomenological study to identify the use of faculty supports. A purposeful sampling strategy was applied to these populations to identify participants in specific selection criteria. Twenty-one participants, who consisted of five faculty members and five or six 2nd-year students from each school, were selected. Data were collected by conducting individual interviews …

Toward Interspecies Reproductive Justice, Asha A. Ramakumar

Animal Law Review

Reproductive justice discourse has largely overlooked non-human animals, despite the parallel forms of biopolitical control exercised over human women and female animals’ reproductive labor. By examining the shared logics underlying the subordina-tion of both human women and dairy cows, this Article argues that any genuine conception of reproductive justice must inter-rogate reproductive exploitation beyond the human experience. Drawing from Michel Foucault’s theory of biopower and Carol J. Adams’ framework of the “absent referent,” this Article elucidates how powerful institutions control those with the capacity for preg-nancy by perpetuating narratives of biological essentialism and obligation.

Part II examines several examples of …

Front Matter, Lewis & Clark Law Review

Animal Law Review

Front Matter contains Table of Contents, masthead, and faculty advisers for Animal Law Review Volume 32, Issue 1.

Psychological Characteristics Of Beginner And Advanced Judokas, Leanardo De Lorenco-Lima, Daniery Rosario, Reury F. P. Bacurau, Leonardo V. Andreato, Stacey A. Gaines

Applied Sport & Performance Psychology | Faculty Scholarship

Several psychological benefits have been associated with judo training, including enhanced cognitive functioning, improved emotional regulation, and higher self-confidence, with training experience being associated with higher levels of several psychological characteristics. Purpose: The current study explored the differences in training and psychological  characteristics  between  beginner  and  advanced  judokas.  Methods:  A  sample  of  146  judokas (77.4% male), including 67 beginners and 79 advanced, between 18 and 45 years of age, completed the Brief Resilience Scale (α = .84), Grit Scale (α = .82), General Self-Efficacy Scale (α = .85), Brief Self-Control Scale (α = .82), Brief Aggression Questionnaire (α = .75), …

Childhood Mental Health And Major Depression In Later Life: A Survival Analysis Across 12 Years, Xiaoling Xiang, Xiafei Wang, Xinyin Zhang, Josephine Abrials

Social Work Faculty Publications

Objectives: This study examined the relationship between childhood mental health conditions and incident major depression in middle-aged and older adults.

Methods: This longitudinal panel study used 12 years of data from 27,220 adults aged 51 and older in the U.S. Health and Retirement Study. Childhood mental health conditions were assessed retrospectively with a question about having a depression, drug/alcohol, or other emotional problem before age 16. Cox regression was used to estimate hazard ratios (HRs).

Results: Childhood mental health conditions were reported by 6.04% of the unweighted sample (n = 1643) and were associated with a more than 2-fold …

The Impact Of Hot V. Cold Water Immersion On Post-Exercise Recovery, Cameron Moss, Aaron Krukemeyer

Williams Honors College, Honors Research Projects

Muscle recovery following exercise-induced soreness has been the focus of extensive research and debate, with Cold Water Immersion (CWI) and Hot Water Immersion (HWI) emerging as two of the most widely used modalities. The purpose of this study was to compare the effects of CWI and HWI on muscle recovery by determining changes in maximal force production of knee extension, range of motion (ROM) of the hip joint in flexion, extension, and abduction, and subjective muscle soreness using a validated Likert scale. Seven male recreational athletes participated in hot and cold-water immersion, and passive recovery. Despite thorough data collection, the …

Cultus: Eco-Phenomenology In The Work Of John Steinbeck, Robinson Jeffers, And Jack London, Carter D. Johnson

Theses and Dissertations--English

In the face of increasingly dire environmental crises, proposed solutions have gravitated toward imperatives for faster, cleaner, and more efficient technologies and resources. While practical solutions are necessary, they are entirely insufficient to deal with an underlying issue driving environmental degradation: unbridled instrumental reason. In this dissertation, I suggest a theoretical posture, cultus, which attempts to balance the necessity of instrumental action with the guiding counterweight of receptivity. Furthermore, I argue that such personal receptivity is uniquely fostered in aesthetic experiences, attuning the individual to the non-identical and renewing a relationship of care.

I examine the life and work of …

Psilocybin-Assisted Therapy And Alcohol Use Disorder, Zoe R. Evans

Theses, Dissertations and Capstones

This current paper has studied whether the psilocybin-assisted treatment has been linked with meaningful shifts in three clinical outcomes among adults 18 years old and above diagnosed with alcohol use disorder (AUD): percentage of heavy drinking days, abstinence rates, and neural responsiveness to alcohol-related cues. A literature review following a systematic approach was performed using guidelines from PRISMA 2020 based on four databases, namely PubMed and PsycINFO, and Scopus and CINAHL, where peer-reviewed articles published between 2015 and 2026 were included. A semi-structured professional interview with a clinical researcher in the Division of Addiction Sciences of Marshall University was also …

Eastern Michigan University, Spring Commencement, May 2, 2026, Eastern Michigan University

Commencement Programs and Materials

No abstract provided.

A Psychometric Evaluation Of Obsessive-Compulsive Items In The Hierarchical Taxonomy Of Psychopathology (Hitop)-Self Report Among Caregivers Of Children, Zach Wasserman

Honors Theses

Introduction: The classification and assessment of psychopathology is a crucial part of understanding mental health. The current model, published in the Diagnostic and Statistical Manual of Mental Disorders, with the current 5th edition (DSM-5; American Psychiatric Association, 2022), utilizes a categorical approach to psychopathology (i.e., one has the disorder or they do not). This creates ~300 diagnoses that are understood as theoretically distinct from one another. In reality, categorical diagnoses are often heavily comorbid (Forbes et al., 2024) and within a diagnostic category there are large amounts of heterogeneity (Feczko & Fair, 2020). To address these issues, dimensional models …

The Divide Of Women’S Health: Systematic Thinking Of Women, Tasfia T. Howlader

Honors Theses

Women’s health has constantly been changing- from public health infrastructure to health policies, and even medical advancements. Yet, the struggles are persistent within the gaps present in women’s health. The Socio-Ecological Model (SEM) explains interactions between different levels of relationships, which result in health outcomes that vary from individual factors to environmental factors. Applying the SEM to describe health disparities can help explain how the relationships an individual has influenced their health. This project serves to exemplify these different levels while discussing the tailoring of services to the needs and the importance of populations based on their experiences. Specifically, adhering …

Displacement And Belonging: The Search For Identity Through Latina Literature, Noelia A. Alvarado Torres

Literary and Intercultural Studies | Senior Theses

How the Garcia Girls Lost Their Accents by Julia Alvarez and Infinite Country by Patricia Engel are two novels that highlight the Latino search for identity and belonging in the United States.  The characters in these books navigate adolescence and adulthood in the face of displacement, each illustrating how history, culture, and society interfere with the search for one’s self. They also highlight the multicultural experience of being shaped by different spaces that at times contradict one another. Furthermore, these books, written by women and with women at the center, bring forth a voice that often gets left out in …

Are They Ready To Speak English With Students? A Clil Adaptation To Thai Efl Classrooms, Wipada Sutthiroj, Phanatdao Chantarasiri

PASAA

No abstract provided.

How Teaching Experience Shapes Efl Teachers’ Integration Of Extramural English In Thai Classrooms, Santipap Upara, Ruedeerath Chusanachoti

PASAA

No abstract provided.

Epistemic Lexical Verbs As Hedging Devices And Their Semantic Prosodies In Applied Linguistics Abstracts In Thai International Journals, Soranut Kumdee

PASAA

No abstract provided.

Brightspace Video Notes, Leanne Harris

Case studies: Digital Education

Enhancing flexible access to module content, particularly announcements, was the key driver behind the use of Video Notes. This approach supports a more personalised form of interaction by using short videos to communicate updates such as timetable changes, assessment deadlines, and grade releases. By allowing students to both see and hear their lecturer alongside reading written information, Video Notes create a more interactive and informative experience. This contributes to a more immersive VLE environment, helping to strengthen the student - lecturer connection by reducing cognitive distance. Overall, the aim is to enhance the student learning experience while supporting Universal Design …

Intraosseous (Io) Analgesia Medication Administration In Orthopaedic Surgery: A Brief Review, Jenna Chrabolowski, Troy B. Puga, Abanoub Attallahm, Mckenna W. Box, John T. Riehl

North Texas GME Research Forum 2026

Introduction

Intraosseous (IO) analgesia is a novel strategy for pain control in orthopaedic surgery. This brief review aims to provide an overview of IO analgesia in orthopaedic surgery.

Methods

A search was conducted across seven databases. Titles and abstracts were screened followed by full-text review for inclusion criteria. Demographics and results were extracted from included articles.

Results

Ten studies met inclusion criteria and involved patients undergoing knee surgery and spinal surgery. IO lidocaine was shown to be effective for postoperative and intraprocedural pain control during vertebroplasty and kyphoplasty. IO morphine and IO NSAIDs were shown to be effective in reducing …

Outcomes After Orif Of Closed Bimalleolar And Trimalleolar Ankle Fractures In Patients With Autoimmune Disease, Mckenna Box, Troy B. Puga, Lachlan Anderson, Alyssa Kozlowski, John T. Riehl

North Texas GME Research Forum 2026

Background: Autoimmune disease is associated with chronic systemic inflammation, immunosuppressive therapy, and increased medical comorbidity, which may influence postoperative outcomes following fracture fixation. Data evaluating outcomes after ankle fracture surgery in this population remain limited. We hypothesized that autoimmune disease would be associated with higher postoperative complication rates following open reduction and internal fixation (ORIF) of closed ankle fractures.

Methods: We performed a retrospective cohort study using a multi-hospital dataset (2017-2025) to identify adult patients undergoing ORIF for closed bimalleolar or trimalleolar ankle fractures. Patients with autoimmune disease were propensity score matched 1:2 to patients without autoimmune disease based on …

Biologic Versus Non-Biologic Immunosuppressant Use And Outcomes After Orif Of Closed Ankle Fractures: A Propensity-Matched Analysis, Mckenna W. Box, Troy B. Puga, Lachlan Anderson, Alyssa Kozlowski, John T. Riehl

North Texas GME Research Forum 2026

Background: The effect of biologic immunosuppressant therapy on postoperative outcomes following ankle fracture open reduction and internal fixation (ORIF) remains unclear, and concerns regarding infection and impaired healing often influence perioperative decision-making. We hypothesized that biologic immunosuppressant use would be associated with higher rates of postoperative complications following ORIF of closed ankle fractures compared with non-biologic immunosuppressant therapy.

Methods: We conducted a retrospective cohort study using a multi-hospital administrative dataset (2017-2025) to identify adult patients undergoing ORIF for closed bimalleolar or trimalleolar ankle fractures who were prescribed immunosuppressive therapy. Patients were categorized based on biologic versus non-biologic immunosuppressant use. A …

Bringing The Outdoors In Through Biophilic Design, Gabriela Miotto Leal

Architectural Studies Honors Papers

This thesis investigates the relationship between architecture, human perception, and well-being through the lens of human-centered and biophilic design. Drawing from philosophical traditions, phenomenology, and contemporary neuroscience, this thesis argues that the built environment is an active agent in shaping cognition, emotion, and lived experience. Architecture is understood as multisensory, embodied, and temporally experienced, influencing individuals in both conscious and nonconscious ways. Through a comparative analysis of three case studies, Paimio Sanatorium, AEA House, and the Amazon Spheres, this research examines how biophilic design principles are incorporated into different contexts such as healthcare, residential, and workplace. Each project demonstrates a …

Investigations Toward A Unified Reaction Pathway Of Thermal And Tbsotf-Mediated Oxidopyrylium-Alkene (5 + 2) Cycloadditions, Adam J. Youman, Samantha N. Rokey, Wentao Guo, Jacob P. Grabowski, Susanna N. Angles, Jacob J. Bulandr, Qing Sun, John R. Goodell, Dean J. Tantillo, T. Andrew Mitchell

Faculty Publications – Chemistry

Oxidopyrylium-based (5 + 2) cycloadditions are crucial reactions to construct seven-membered carbocycles containing an ether bridge (i.e. oxabicyclo[3.2.1]octanes). Intramolecular silyloxypyrone-based (5 + 2) cycloadditions were investigated and revealed several features: (1) the TBDPS thermal process proceeds via a zwitterionic oxidopyrylium intermediate similar to previously reported TBS variants; (2) the TBSOTf-mediated reaction proceeds through a cationic oxidopyrylium intermediate; (3) quantum chemical calculations predict a stepwise process for an electron-rich dipolarophile for each set of conditions. The thermal silyloxypyrone-based (5 + 2) cycloadditions were extremely dependent on the nature of the dipolarophile and the silyl transfer group. The TBDPS enhances the …

Advancing Generative Methods For Multimodal Data Analysis, Rabeya Tus Sadia

Theses and Dissertations--Computer Science

The integration and modeling of high-dimensional, heterogeneous biological data remain central challenges in computational biology due to complex feature dependencies and pervasive missingness. This dissertation addresses these challenges by developing novel generative frameworks for multimodal data reconstruction, imputation, and interaction prediction. In generative modeling, we focus on capturing structural and causal dependencies in sparse biological systems. We first introduce CausalGeD, a causality-aware diffusion framework that leverages Granger-causal attention for biologically coherent spatial gene expression generation. Next, we propose CausalGenDiff, which combines VAE-guided latent representations with causal diffusion to enable robust reconstruction across spatial and single-cell modalities. We further present DepMicroDiff, …

Assessing The Diversity And Composition Of Crayfish Assemblages In The Ogeechee River Basin, Reginald Turner

College of Graduate Studies: Theses & Dissertations

Crayfish assemblage composition in the southeastern United States is understudied relative to other aquatic taxa, such as aquatic insects and fishes, and the Coastal Plain watersheds of that region are particularly underrepresented in the contemporary literature on this topic. For example, although 38% of the crayfish species in Georgia are considered “species of greatest conservation need,” most of the distributional data used to make these designations are outdated, with some dating back over 50 years. This thesis sought to update our understanding of the contemporary distributions of crayfish species within the Ogeechee River Basin (ORB), a watershed in southeastern Georgia …

Roadway Runoff Impacts To Trout Streams Studies For Ms4 Permit, Jobayed Hossain Badhan

College of Graduate Studies: Theses & Dissertations

Roadway runoff from Georgia Department of Transportation (GDOT) highway infrastructure poses measurable, but temporally constrained threats to cold-water trout ecosystems in northern Georgia. This study investigates temperature and dissolved oxygen (DO) dynamics in three secondary trout streams receiving GDOT roadway discharges, with the primary objective of evaluating compliance with Georgia Rule 391-3-6-.03(6)(ii),(v) under the Municipal Separate Storm Sewer System (MS4) permit framework. Field monitoring was conducted from April 2024 through October 2025 across two consecutive summer seasons using a tiered, multi-instrument approach: YSI ProDSS handheld grab sampling provided regulatory-grade reference measurements; HOBO MX-801 optical DO dataloggers recorded continuous 5-minute-interval temperature …

Mechanical Properties And Crystallization Of Polybutylene Terephthalate Reinforced With Glass Flakes And Aluminum Powder, Nattakarn Hongsriphan, Pajaera Patanathabutr

Journal of Metals, Materials and Minerals

This research investigated mechanical properties and crystallization of poly(butylene terephthalate) composites by adding glass flakes (GF) and aluminum particles (Al). The concentration of the GF was 3 wt% or 5 wt%, and the Al was 0.5 wt% or 1.0 wt%. The stress-strain curves of the PBT-based composites showed yielding and necking. The PBT/GF/Al composites with GF/Al ratios of 3/0.5 wt/wt%, 3/1.0 wt/wt%, 5/0.5 wt/wt%, and 5/1.0 wt/wt% had Young’s moduli of 11.44%, 11.70%, 16.81%, and 19.31% higher than that of neat PBT, respectively. In the presence of Al at 1.0 wt%, the flexural modulus of the PBT/GF/Al composites increased to …

Development Of Poly(Lactic Acid)/Ethylene-Propylene-Diene Monomer/Cellulose Composites Using Cellulose Extracted From Hemp Biomass For Plastic Packaging Applications, Supanicha Alapon, Natthanich Thongmee, Wikoramet Teeka, Pattara Somnuake, Sirirat Wacharawichanant

Journal of Metals, Materials and Minerals

Poly(lactic acid)/ethylene-propylene-diene monomer (EPDM)/cellulose composites using cellulose derived from hemp biomass (CHB) were investigated in this research. Morphology, chemical structures, functional groups, and crystallinity of CHB were characterized, observing a size of 135 ± 32 μm from SEM images with high purity and crystallinity from FT-IR and XRD spectroscopy. The optimized CHB was incorporated at 1 phr, 3 phr, and 5 phr into PLA/EPDM blends at 90/10 w/w. The polymer composites were prepared using an internal mixer, and samples were produced by compression molding for mechanical and thermal testing. The results indicated that the EPDM phase dispersed as droplets in …

Development Of 4-Vinylbenzyl Chloride (Vbc) Grafted Onto Branched Polyethylenimine (Pei) Onto Bacterial Cellulose Sheet By Gamma-Induced Irradiation Technique For Cu Ion Adsorption, Methinee Wongwai, Supitchaya Kulratkitiwong, Thitirat Rattanawongwiboon, Sarute Ummartyotin

Journal of Metals, Materials and Minerals

Bacterial cellulose extracted and purified from Nata de coco was employed as a platform for Cu2+ ion adsorption. 4-vinylbenzyl chloride (VBC) was successfully grafted at the hydroxyl position by using gamma irradiation. The optimum was typically related to VBC concentration of 2% (v/v) and a radiation dose of 50 kGy. FTIR significantly reported the functional group of C-Cl related to VBC. No change of crystallinity and morphology was observed. The thermal decomposition was stable up to 200℃. The modification of branched polyethylenimine (PEI) was prepared in order to change the functionality to N‒H stretching. This was expected to adsorb Cu2+ …