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There’S No “Gender” In Team: Developing State Policies For The Inclusion Of The Transgender Interscholastic Athlete, Brianna Weppler Jan 2022

There’S No “Gender” In Team: Developing State Policies For The Inclusion Of The Transgender Interscholastic Athlete, Brianna Weppler

Touro Law Review

The transgender athlete is a relatively new concept challenging the norm of gender division in sports. Multiple states across the United States have yet to update their policies to include the transgender athlete in interscholastic athletics. State policies that do include transgender student athletes are currently being challenged on the grounds that they violate Title IX of the Educational Amendments to the 1964 Civil Rights Act. This review considers the different state policies dictating the inclusion of transgender student athletes in school sports. After evaluating the impact of omitting transgender students from participating on sports teams, this review maintains that …


The Limitations And Alternatives To Expanding The Equal Pay Act Under Bostock V. Clayton County, Ga., Valentina Wilson Jan 2022

The Limitations And Alternatives To Expanding The Equal Pay Act Under Bostock V. Clayton County, Ga., Valentina Wilson

University of San Francisco Law Review

No abstract provided.


American Motherhood - A Taking, Nicole Knight Jan 2022

American Motherhood - A Taking, Nicole Knight

Mitchell Hamline Law Journal of Public Policy and Practice

No abstract provided.


Improving Three-Dimensional Instructional Practices Via Professional Development, Alethea Henry Jan 2022

Improving Three-Dimensional Instructional Practices Via Professional Development, Alethea Henry

Electronic Theses and Dissertations

The purpose of this applied research study was to improve the use of three-dimensional pedagogy in science classes in chronically low-performing schools. The need to build teacher capacity became evident after the state adopted more rigorous science standards revealing deficits in teachers’ pedagogical content knowledge. This study utilized two elements, three-dimensional professional development and the science cadre, to build teacher capacity as well as foster collaboration and create buy-in throughout the district among science leaders. Data collected and analyzed from classroom observations, student surveys, and teacher interviews revealed improved usage of three-dimensional instruction and increased buy-in throughout the district to …


Using Image To Assist Students In Construct Searching Concepts And Framing Research Questions, Junli Diao Jan 2022

Using Image To Assist Students In Construct Searching Concepts And Framing Research Questions, Junli Diao

Open Educational Resources

No abstract provided.


The Efficacy Of Probiotics On Overall Quality Of Life By Gender, Melissa Kalman, Kirsten Soderblom Jan 2022

The Efficacy Of Probiotics On Overall Quality Of Life By Gender, Melissa Kalman, Kirsten Soderblom

Loma Linda University Research Reports

Introduction:

In the 1950s, German scientist Werner Kollath coined the term probiotic, which is Latin for, “for life”. To be considered a probiotic, a product must consist of live microorganisms and provide health benefits to the host when ingested in sufficient amounts. The microorganisms in probiotics provide numerous health benefits through immunologic mechanisms. Recent research shows probiotics may provide benefits to those experiencing stress, including general anxiety and stressors, as well as improve human immunity and overall quality of life. There is a lack of research concerning probiotics and the differences in physiological responses comparing males and females.


Articulating Korean American Women’S Power Amidst Conflicts Of Colonialism And War In Helie Lee’S Still Life With Rice, Kittiphong Praphan Jan 2022

Articulating Korean American Women’S Power Amidst Conflicts Of Colonialism And War In Helie Lee’S Still Life With Rice, Kittiphong Praphan

Manusya, Journal of Humanities

Gender is a quintessential issue in Asian American literature, since Asian Americans are seen as weak with feminine qualities, according to the Western colonial concept. This paper examines Korean American women’s power through an analysis of Hongyong, the female protagonist in Helie Lee’s Still Life with Rice, who survives Japanese colonization in Korea and the Korean War and finally starts her new life as a Korean American woman in the United States. Hongyong goes beyond the concept of patriarchy in Korea and rescues herself and her family with her intelligence, determination, power, and bravery. As an Asian woman who …


Morpho-Physiological Diversity Of Barley (Hordeum Vulgare L.) Germplasm For Heat Tolerance, Muhammad Ashraf, Fahad Al-Qurainy, Muhammad Sajid Aqeel Ahmad, Muhammad Yasir Iqbal, Adnan Mehmood, Alia Riffat, Ambreen Khadija Alvi Jan 2022

Morpho-Physiological Diversity Of Barley (Hordeum Vulgare L.) Germplasm For Heat Tolerance, Muhammad Ashraf, Fahad Al-Qurainy, Muhammad Sajid Aqeel Ahmad, Muhammad Yasir Iqbal, Adnan Mehmood, Alia Riffat, Ambreen Khadija Alvi

Turkish Journal of Botany

The aim of the present study was to examine the diversity for heat tolerance in a set of 105 accessions using some key morphophysiological attributes. The data was standardized by calculating percent change over control, and used for phonetic analysis and construction of dendograms based on distance matrix (all primary data is given as supplementary material listed in statistical analysis section of Materials and Methods). These distance matrices were then used for the unweighted pair group method with arithmetic mean (UPGMA) cluster analysis using the sequential agglomerative hierarchical nonoverlapping (SAHN) method. The cluster analysis indicated some potential attributes that could …


In Silico Analysis Of Xth Gene Family From Barley (Hordeum Vulgare L.) And Their Comparative Expression Analysis During Germination, Hülya Akdemi̇r Koç, Merve Seven, Ümi̇t Cem Derman, Andrew John Harvey Jan 2022

In Silico Analysis Of Xth Gene Family From Barley (Hordeum Vulgare L.) And Their Comparative Expression Analysis During Germination, Hülya Akdemi̇r Koç, Merve Seven, Ümi̇t Cem Derman, Andrew John Harvey

Turkish Journal of Botany

Changes in plant cell walls are critical for expansion and growth. Xyloglucan endotransglycosylase/hydrolase (XTH) enzymes are the major modifiers of xyloglucan within the cell wall and are present as large gene families. Despite the paucity of xyloglucan in barley, our analyses of the barley genome revealed at least 42 XTH genes, the most XTH members recorded for a monocot genome to date. In this paper, we show a detailed look at the barley XTH gene family, including detailed bioinformatics analyses of conserved protein motifs and structure, phylogenetic relationships, and a comparison of the expression patterns during germination and seedling growth …


Cover And Contents Jan 2022

Cover And Contents

Turkish Journal of Botany

No abstract provided.


New Species And New Record In Agaricus Subg. Minores From India, Entaj Tarafder, Arun Kumar Dutta, Krishnendu Acharya Jan 2022

New Species And New Record In Agaricus Subg. Minores From India, Entaj Tarafder, Arun Kumar Dutta, Krishnendu Acharya

Turkish Journal of Botany

Two new species of Agaricus, namely A. midnapurensis and A. purpureosquamulosus, belonging to A. subg. Minores, are proposed here as new to science based on specimens collected in West Bengal, India. Agaricus midnapurensis is distinguished by its medium-sized basidiomata with a pileus covered by greyish brown to brown or dark brown squamules, ellipsoid to broadly ellipsoid basidiospores with a mean value of 7.3 × 5.4 µm, and broadly clavate to pyriform cheilocystidia, 22-28 × 10-14 µm. Agaricus purpureosquamulosus has purplish coloured pileus squamules, ellipsoid to elongate basidiospores with a mean value of 7.3 × 4.5 µm, and clavate cheilocystidia measuring …


Shackletonia Backorii - A New Species Of Lichenised Fungus From James Ross Island (Antarctic Peninsula), Mehmet Gökhan Halici, Mi̇that Güllü, Ekrem Bölükbaşi, Merve Kahraman Yi̇ği̇t Jan 2022

Shackletonia Backorii - A New Species Of Lichenised Fungus From James Ross Island (Antarctic Peninsula), Mehmet Gökhan Halici, Mi̇that Güllü, Ekrem Bölükbaşi, Merve Kahraman Yi̇ği̇t

Turkish Journal of Botany

The new lichen species Shackletonia backorii Halıcı, Güllü & Kahraman is described from James Ross Island, which is located in the North-East Antarctic Peninsula region. The new species is morphologically most similar to S. insignis (Søchting & Øvstedal) Søchting, Frödén & Arup, which was described from Livingstone Island (North-West Antarctic Peninsula region). These two species have a similar bluish grey to blackish thallus with a microfruticose and coralloid structure and red brown or almost black zeorine apothecia, but S. backorii has rhomboid ascospores and grows on soil whereas S. insignis has ellipsoid ascospores and occurs in sheltered crevices of rocks. …


Genome-Wide Identification And Evolutionary Analysis Of Cngc Gene Families In Sixteen Brassicaceae Plant Genomes, Akram Ali Baloch, Kaleem U. Kakar, Asma Abro, Muhammad Mushtaq, Zarqa Nawaz, Abrar Hussain Jan 2022

Genome-Wide Identification And Evolutionary Analysis Of Cngc Gene Families In Sixteen Brassicaceae Plant Genomes, Akram Ali Baloch, Kaleem U. Kakar, Asma Abro, Muhammad Mushtaq, Zarqa Nawaz, Abrar Hussain

Turkish Journal of Botany

Cyclic nucleotide-gated channels (CNGCs) are ligand-gated calcium signaling channels, play vital biological functions. Nonetheless, the CNGC gene families have not been well studied in Brassicaceae which includes commercially important and evolutionary model crops. Here, using in silico approaches, we recognized 414 CNGC genes in sixteen sequenced genomes of Brassicaceae species, which represent 10 genera of 8 tribes, ranging between 10-51 genes. These CNGCs can be classified into four main groups (I-IV) and two subgroups (IV-A and IV-B), of which, Group-II CNGC is the oldest that has gradually disappeared from the Arabis alpina L. genome. These results present a comprehensive overview …


Phytochemical Constituents Of Aquilaria Malaccensis Leaf Extract And Their Anti-Inflammatory Activity Against Lps/Ifn-Γ-Stimulated Raw 264.7 Cell Line, Eman Ramadan, Manar A. Eissa, Yumi Z. H-Y Hashim, Dina M. El-Kersh Jan 2022

Phytochemical Constituents Of Aquilaria Malaccensis Leaf Extract And Their Anti-Inflammatory Activity Against Lps/Ifn-Γ-Stimulated Raw 264.7 Cell Line, Eman Ramadan, Manar A. Eissa, Yumi Z. H-Y Hashim, Dina M. El-Kersh

Pharmacy

This study aims to identify the major phytochemical constituents in Aquilaria malaccensis (Thymelaeaceae) ethanolic leaf extract (ALEX-M) and elucidate their ability to suppress nitric oxide (NO) production from a murine macrophage-like cell line (RAW 264.7) stimulated by lipopolysaccharide (LPS) and interferon-γ (IFN-γ). Dichloromethane (DCM) and ethyl acetate (EtOAc) fractions of ALEX-M were subjected to column chromatography. Eight known compounds were isolated for the first time from this species. Compounds were identified using spectroscopic techniques (IR, UV, HRESIMS, and 1D and 2D NMR). Anti-inflammatory activity of both extract and isolated compounds were investigated in vitro. The fractions offered the isolation of …


Thinking, Faster And Slower: Toward A Dynamic View Of Organizational Cognition, Joseph Vukov, Charles Lassiter Jan 2022

Thinking, Faster And Slower: Toward A Dynamic View Of Organizational Cognition, Joseph Vukov, Charles Lassiter

Philosophy Faculty Scholarship

Our abilities as humans—i.e. our powers—aren’t always stable across contexts. In particular, sociocultural contexts can amplify or dampen manifestations of our powers. In particular, the same sociocultural intervention can catalyze a manifestation for one sort of individual and inhibit it for another. We develop these insights within the conceptual framework of causal powers realism: An ontological theory built on the idea that causal influences and processes should ultimately be understood as the manifestation of powers. Developing capacities’ dynamism in this framework enables articulation of novel insights. First, that our psychological capacities are context-sensitive and dynamic all the way down. Second, …


Empowering Biosemiotics, Charles Lassiter Jan 2022

Empowering Biosemiotics, Charles Lassiter

Philosophy Faculty Scholarship

One way to understand the basic semiotic relation is that a sign-vehicle signifies an object to an interpretant. Biosemioticians sometimes talk about this relationship in terms of “codes”. When thinking about this relationship in the context of language, a natural move is to conceptualize semiotic relationships among speakers, meanings, and utterances as codes: speakers encode messages in sentences, which are then decoded by an interpreter. This view of communication is inconsistent with core tenets of a distributed approach to language, which holds that language is an embodied and encultured activity taking place across multiple timescales. I argue that a neo-Aristotelian …


Neuroprotective Effect Of Liraglutide In An Experimental Mouse Model Of Multiple Sclerosis: Role Of Ampk/Sirt1 Signaling And Nlrp3 Infammasome, Marwa Safar Jan 2022

Neuroprotective Effect Of Liraglutide In An Experimental Mouse Model Of Multiple Sclerosis: Role Of Ampk/Sirt1 Signaling And Nlrp3 Infammasome, Marwa Safar

Pharmacy

The heterogeneous nature of multiple sclerosis (MS) and the unavailability of treatments addressing its intricate network and reversing the disease state is yet an area that needs to be elucidated. Liraglutide, a glucagon-like peptide-1 analogue, recently exhibited intriguing potential neuroprotective effects. The currents study investigated its potential effect against mouse model of MS and the possible underlying mechanisms. Demyelination was induced in C57Bl/6 mice by cuprizone (400 mg/kg/day p.o.) for 5 weeks. Animals received either liraglutide (25 nmol/kg/day i.p.) or dorsomorphin, an AMPK inhibitor, (2.5 mg/ Kg i.p.) 30 min before the liraglutide dose, for 4 weeks (starting from the …


Anthropogenic Influences On The Decline, Restoration, And Eco-Evolutionary Dynamics Of Lake Superior’S Coaster Brook Trout, Austin Johnson Jan 2022

Anthropogenic Influences On The Decline, Restoration, And Eco-Evolutionary Dynamics Of Lake Superior’S Coaster Brook Trout, Austin Johnson

Dissertations, Master's Theses and Master's Reports

The coaster brook trout is a life history variant of the brook trout (Salvelinus fontinalis) that is characterized by either lake residency or migration between stream and lake habitats. Coaster brook trout were once widespread throughout Lake Superior and its tributaries, but populations declined sharply in the late 19th and early 20th centuries. Historically, brook trout were a popular target of recreational and subsistence fishing in the Lake Superior basin, and it has been hypothesized that angling pressure combined with multiple forms of industrial development are what drove the coaster brook trout’s decline. In the mid …


Per- And Polyfluoroalkyl Substances Mitigation From Contaminated Groundwater Using Halophyte And Cow Bone Biochars, Bailey Papes Jan 2022

Per- And Polyfluoroalkyl Substances Mitigation From Contaminated Groundwater Using Halophyte And Cow Bone Biochars, Bailey Papes

Dissertations, Master's Theses and Master's Reports

Per- and polyfluoroalkyl substances (PFAS) groundwater contamination is a growing concern for the Brackish Groundwater National Desalination Research Facility. Two of the four wells onsite are contaminated with perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), and perfluorohexane sulfonic acid (PFHxS). The removal of PFAS by adsorption onto powder activated carbon (PAC) is promising, but the production of PAC is energy intensive and expensive. A potential cost-effective alternative to PAC is biochar. This study quantified the capacities of two halophyte biochars, cow bone biochar and PAC to adsorb PFOA, PFOS, and PFHxS from brackish groundwater. The three biochars were ineffective at …


Simulating Groundwater Pollutant Transport For Remediation Design, Antrim County, Michigan, Abilynn Raetz Jan 2022

Simulating Groundwater Pollutant Transport For Remediation Design, Antrim County, Michigan, Abilynn Raetz

Dissertations, Master's Theses and Master's Reports

Located in Antrim County, Michigan between the coasts of Torch Lake and Lake Michigan is a hydrocarbon plume that has impacted surrounding residential wells. The plume is comprised of benzene, toluene, ethylbenzene, and xylenes (BTEX) and primarily resides in the shallowest groundwater aquifer. The plume is suspected of having originated from an underground storage container that was removed in 1979. A conceptual model was developed for the site, comprising of a simplified hydrogeological model. Groundwater modeling was performed using Aquaveo's groundwater modeling software (GMS). PEST parameter calibration was performed on the hydraulic conductivity and recharge values using data from surrounding …


Conservation Value Of Working Landscapes In Mesoamerica For Nearctic-Neotropical Migratory Birds, Samuel L. Oliveira Jan 2022

Conservation Value Of Working Landscapes In Mesoamerica For Nearctic-Neotropical Migratory Birds, Samuel L. Oliveira

Dissertations, Master's Theses and Master's Reports

Populations of many of Nearctic-neotropical migratory birds have declined in the past several decades, recent estimates suggested a dramatic loss of 2.5 billion birds over the past 50 years in North America. Habitat loss and degradation represent a major threat in the tropics. Managed agroecosystems have the potential to mitigate some impacts of land conversion, however, little is known regarding the habitat quality provided by working landscapes in the overwintering range. In this research, we surveyed the migratory bird community in the rapidly expanding oil palm plantations in southern Mexico; and also the declining population of the Wood Thrush ( …


From Thermal Springs To Subway Benches: Exploring The Diversity Of Carbon Monoxide Dehydrogenases Through Metagenomes, Phylogenetics, And Machine Learning, Isaac Bigcraft Jan 2022

From Thermal Springs To Subway Benches: Exploring The Diversity Of Carbon Monoxide Dehydrogenases Through Metagenomes, Phylogenetics, And Machine Learning, Isaac Bigcraft

Dissertations, Master's Theses and Master's Reports

Carbon monoxide is well known as a toxic gas but can also be an important input and intermediary for microbial metabolisms. Carbon monoxide dehydrogenases (CODHs) serve as key enzyme complexes for a variety of microbial carbon monoxide (CO) utilization pathways. Such pathways include the Wood-Ljungdahl pathway, which is important in methanogenesis and acetogenesis, metal and sulfate reduction pathways, hydrogen production, and others. The CODH enzymes allow microbes to turn the traditionally toxic waste gas of CO into a useful carbon and energy source. Despite the flexibility of CODH enzymes, the use of carbon monoxide is still believed to be a …


Effects Of Mindfulness And Stress Management On Neurocardiovascular And Psychological Outcomes, Aditi P. Vyas Jan 2022

Effects Of Mindfulness And Stress Management On Neurocardiovascular And Psychological Outcomes, Aditi P. Vyas

Dissertations, Master's Theses and Master's Reports

There has been a higher prevalence of developing anxiety due to frequent episodes of stress among adults in recent years. Chronic anxiety can contribute to the prevalence of elevated blood pressure and hypertension. High anxiety and stress also contribute to overactivation of the sympathetic nervous system which can be quantified by increased muscle sympathetic nerve activity (MSNA). Sympathetic overactivation can lead to vasoconstriction and loss of arterial elasticity. Anxiety, MSNA, blood pressure, and arterial stiffness are all interconnected, thus studying these relationships is crucial to understand the underlying mechanisms for prevention and treatment of cardiovascular disease (CVD). Non-pharmacological and mind-body …


Computational Study Of Quorum Quenching Of N-Acyl Homoserine Lactones By Ion Pairing To Cations, Ashen Anuradha Suduweli Kondage Jan 2022

Computational Study Of Quorum Quenching Of N-Acyl Homoserine Lactones By Ion Pairing To Cations, Ashen Anuradha Suduweli Kondage

Dissertations and Theses

Biofilms are the default state of microbial life and their formation on surfaces influences many processes. The coordinated behavior of microorganisms including their growth into biofilms occurs through a process termed quorum sensing during which they excrete specific signaling molecules called autoinducers. Recently it has been observed that Ag+ and Cu2+ ions interact with N-hexanoyl-L-homoserine autoinducers thereby inhibiting quorum sensing. Such inhibitors are called quorum quenchers. In this study, we have used density functional theory (DFT) calculations to study the ion pairing between select cations and short chained N-acyl-homoserine lactone (AHL) type autoinducers that are used by gram negative bacteria. …


Green Synthesis, Characterisation Of Au And Ag Nanoparticles By Various Bioextracts And Their Usability At Graphite Electrode Modification, Emi̇ne Arslan, Ender Bi̇çer, Eli̇f Sekmen, Semi̇ha Çakir Jan 2022

Green Synthesis, Characterisation Of Au And Ag Nanoparticles By Various Bioextracts And Their Usability At Graphite Electrode Modification, Emi̇ne Arslan, Ender Bi̇çer, Eli̇f Sekmen, Semi̇ha Çakir

Turkish Journal of Chemistry

In this study, the biosynthesis of Au and Ag nanoparticles (AuNp and AgNp) with a green chemistry approach was performed by using bioextracts of various fruits and vegetables (Lycopersicon esculentum (LE), Cucumis sativus (CS), Malus domestica (MD), Cucurbita pepo (CP), Apiumgraveolens var. rapaceum (AVR), Prunus cerasifera (PC), Oleraceae var. botrytis (OVB)). In the determination of optimum experimental conditions, the parameters such as the type and concentration of bioextract, concentration of metal ion solutions, the ratio of metal ion solution to bioextract, pH, reaction time and temperature were found to be significant. The characterisation of AuNp and AgNp synthesized by providing …


Synthesis And Reactions Of Di(Thiophen-2-Yl)Alkane Diones: Cyclocondensation, Teki̇n Artunç, Abdullah Menzek Jan 2022

Synthesis And Reactions Of Di(Thiophen-2-Yl)Alkane Diones: Cyclocondensation, Teki̇n Artunç, Abdullah Menzek

Turkish Journal of Chemistry

Known 1,6-di(thiophen-2-yl)hexane-1,6-dione (2) and novel 1,7-di(thiophen-2-yl)heptane-1,7-dione (4) were obtained from the reactions of thiophene with the corresponding diacyl chlorides. Furthermore, compounds with furan and pyrrole units in place of thiophene units in compound 2 were obtained in the same way. Bromination of 2 and 4 gave bromides regioselectively. The reaction of each of the compounds 2 and 4 in HOAc medium yielded cyclocondensation products. In total, four known and eleven novel compounds were synthesized.


Schiff Base Containing Pyridine Groups Functionalized Water-Soluble Phthalocyanine: Synthesis, Photo-Physicochemical Properties, And Bovine Serum Albumin Binding Behavior, Öznur Dülger, Ali̇ Erdoğmuş Jan 2022

Schiff Base Containing Pyridine Groups Functionalized Water-Soluble Phthalocyanine: Synthesis, Photo-Physicochemical Properties, And Bovine Serum Albumin Binding Behavior, Öznur Dülger, Ali̇ Erdoğmuş

Turkish Journal of Chemistry

The novel pyridine bearing schiff base substituted metal-free (9), zinc(II) phthalocyanine (10), and its quaternized derivative (11) were designed and synthesized. These phthalocyanines were fully characterized by spectroscopic methods (FT-IR, UV-Vis, MALDI-TOF, and 1H NMR). The photo-physicochemical properties of these phthalocyanines were investigated in both DMSO and DMF for 10 and in both DMSO and aqueous solution for 11. The addition of pyridine bearing Schiff base groups as peripheral ligands showed an improvement in the photophysical and photochemical properties. In addition, a spectroscopic investigation of the binding behavior of the water-soluble zinc (II) phthalocyanine …


Comparison Of Denaturing Agent Effects In Enzymatic N-Glycan Release For Human Plasma N-Glycan Analysis, Haci Mehmet Kayili, Rokia Sakhta, Beki̇r Sali̇h Jan 2022

Comparison Of Denaturing Agent Effects In Enzymatic N-Glycan Release For Human Plasma N-Glycan Analysis, Haci Mehmet Kayili, Rokia Sakhta, Beki̇r Sali̇h

Turkish Journal of Chemistry

Glycosylation is an essential posttranslational modification observed in the living proteome. Glycosylation profiles in glycoproteins can change in commonly observed diseases such as cancer. Identifying these changes is crucial in discovering new biomarkers for the early diagnosis of cancer. One of the main steps of N-glycan analysis is to release N-glycans from glycoproteins by specific enzymes. The study compares common denaturing agent combinations used in N-glycan release methods. In the study, human plasma was used to test the release methods of N-glycans containing different detergent combinations. The released N-glycans were labeled with the procainamide tag, …


Interaction Of The Nitrogen-Containing Carbon Backbone Polymers With Essential Α-Amino Acids, Andrey Sorokin, Maria Lavlinskaya Jan 2022

Interaction Of The Nitrogen-Containing Carbon Backbone Polymers With Essential Α-Amino Acids, Andrey Sorokin, Maria Lavlinskaya

Turkish Journal of Chemistry

The aim of this work is to research the interactions of water-soluble nitrogen-containing copolymers with essential amino acids in aqueous media. For this, poly(N-vinylformamide-co-N-vinylimidazole) and poly(N-vinylcaprolactam-co-N-vinylimidazole) random copolymers were synthesized by free radical polymerization. The products obtained are characterized by GPC, DLS, and FTIR. The copolymers have a narrow molecular weight distribution and low dispersity. The interactions of the obtained copolymers with histidine, proline, arginine, leucine, phenylalanine, and methionine were researched by UV spectroscopy, FTIR, and TEM. It was found that conjugation of the copolymers with amino acids correlates with the copolymer …


The Investigation Of Parameters Affecting Ibrutinib Release From Chitosan/ Tripolyphosphate/Carbon Nanofiber Composite Microspheres, Canan Armutcu Jan 2022

The Investigation Of Parameters Affecting Ibrutinib Release From Chitosan/ Tripolyphosphate/Carbon Nanofiber Composite Microspheres, Canan Armutcu

Turkish Journal of Chemistry

This study described the performance of carbon nanofiber modified chitosan (CNF@CS) composite microspheres for the controlled release of the Ibrutinib (IBR) drug. The surface morphology, particle sizes, and functional group contents of the microspheres were characterized by attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FTIR), scanning electron, and optical microscopy measurements. The obtained data demonstrated that the addition of CNF to the microsphere increased the encapsulation efficiency of the IBR while allowing the controlled and gradual release of the drug. In terms of the encapsulation efficiency and drug release rate, IBR@CS/TPP/CNF microspheres, achieving drug encapsulation efficiency of 83.09%, have the most …