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A Novel Drug To Induce Apoptosis In Advanced Prostate Cancer Cells, Parshva A. Sanghvi

Honors Undergraduate Theses

Prostate cancer is one of the leading causes of death for men in America as approximately 1 in 41 men will have prostate cancer. In this research, we focus on enzalutamide-resistant prostate cancer cells as cell resistance to enzalutamide is a prevalent obstacle in treating prostate cancer. We tested a novel compound library at different doses and observed each compound's efficacy in inducing apoptosis in enzalutamide-resistant cells. Furthermore, we analyzed the mechanism by which apoptosis was induced in compounds that showed a high efficacy at lower doses. Overall, we found that Darapladib shows promising results in treating cells that have …

Book Review: Somewhere Between Bitter And Sweet, Emily Brown

The Utah English Journal

Laekan Zea Lemp's debut novel, Somewhere Between Bitter and Sweet, is a story about dreams and fears in a vibrant Latinx community. Penelope Prado dreams of opening her own pasteleria next door to her father's restaurant, Nacho's Tacos, where she currently works. However, her parents have different plans for her life--plans that involve college and leaving their struggling family business behind to find greater opportunities. Now, she not only fears disappointing them but also fears her own weaknesses will keep her from ever realizing her dream. When she reveals a disappointing secret to her parents, Pen is immediately forced to …

Book Review: Race Against Time, Amanda Burrows

The Utah English Journal

US Supreme Court, 1923. More than 50 years after the ratification of the 14th amendment and the end of the Civil War, the promise of" equal protection of the laws" was under attack. Moore vs Dempsey was the first case where the federal court overturned the ruling of a state court; more significantly, it was the first case to rule in favor of a black defendant. Four years earlier, in Elaine, Arkansas, a meeting of sharecroppers at a local church had been bombarded with gunfire. After a few days of rioting, -five white men and an uncounted number of black …

Uri Undergraduate And Graduate Course Catalog 2022-2023, University Of Rhode Island

URI Course Catalogs Archive

This is a downloadable PDF version of the University of Rhode Island course catalog.

2021-2022 Continuous Improvement, Southwestern Oklahoma State University

Assessment Center Reports

The 2021-2022 Continuous Improvement report produced by the SWOSU Assessment Center.

Efficacy Of Prebiotic Dietary Intervention To Mitigate Risks For Dementia Via The Gut-Brain Axis, Lucille M. Yanckello

Theses and Dissertations--Pharmacology and Nutritional Sciences

Alzheimer’s disease (AD) is the most common form of dementia with various risk factors including age, environmental factors such as brain injury and genetic factors, such as the E4 allele of the Apolipoprotein gene. Presence of the APOE4 allele increases AD risk by two- to four- fold. Recent studies have shown that mild traumatic brain injury (mTBI), even without loss of consciousness, increases risk of dementia diagnosis by more than two-fold in military personnel and is also a significant environmental risk factor for developing dementia in the general population. The gut-brain axis (GBA) or bi-directional communication between the brain and …

Decolonizing The Map: Indigenous Maps And Gis, Henry Osborne Beimers

All Graduate Theses, Dissertations, and Other Capstone Projects

Indigenous mapping practices have yet to be widely considered by geographers outside of a historical context. In this paper I critique the geographic research paradigm through the lens of settler colonial and critical cartographic theory. I present evidence for the value of Indigenous mapping practices through a historical-critical GIS analysis of two Indigenous maps, and a creation of a story map to present those results. Finally, I suggest future routes to integrate digital mapping and Indigenous mapping practices, for pedagogy, and for preserving cultural resources, language, land, and traditional Indigenous knowledge.

The Assessment Of Emergency Preparedness Among University Students, Arliah Cox

All Graduate Theses, Dissertations, and Other Capstone Projects

University students have been an understudied population when it comes to the topic of emergency/ disaster preparedness. While there have been a few studies carried out to examine students’ perceptions of preparedness, the level of preparedness must be determined to be able to close the gap when it comes to barriers preventing them from being prepared. One hundred and eighty-seven undergraduate participants at a Midwestern university completed both online and in-person surveys in March 2022. The survey included questions regarding emergency/ disaster preparedness, perception of being prepared, and barriers which can prevent preparedness. Results showed that a lack of time …

Investigating Anxiety-Like Behavior As A Non-Motor Side Effect Of Deep Brain Stimulation Of The Subthalamic Nucleus In A Parkinsonian Rat Model, Carter Mulder

All Graduate Theses, Dissertations, and Other Capstone Projects

Parkinson’s disease (PD) is estimated to impact nearly 10 million people globally and is estimated to increase in the future. PD is a progressive neurodegenerative disease that worsens through continuous cell death of dopaminergic neurons. This cell death can create motor symptoms such as bradykinesia, tremor, and muscular rigidity. Subthalamic nucleus deep brain stimulation, STN DBS, is a surgical intervention which places stimulating electrodes in the STN greatly improving motor symptoms. However, STN DBS has been reported to possibly influence non-motor symptoms such as anxiety both acutely and long-term, which decreases the quality of life for those with PD. We …

Data Science: A Study From The Scientometric, Curricular, And Altmetric Perspectives, Michael Joseph King

Selected Full Text Dissertations, 2011-

This research explores the emerging field of data science from the scientometric, curricular, and altmetric perspectives and addresses the following six research questions: 1. What are the scientometric features of the data science field? 2. What are the contributing fields to the establishment of data science? 3. What are the major research areas of the data science discipline? 4. What are the salient topics taught in the data science curriculum? 5. What topics appear in the Twitter-sphere regarding data science? 6. What can be learned about data science from the scientometric, curricular, and altmetric analyses of the data collected? Using …

The Syntax Of Sports, Class 4: Parallel Structure, Patrick Barry

Books

"Once you find the right structure, perhaps it will be easier to find the right content.” That’s one of the key insights from this fourth book in the series The Syntax of Sports. Others include:

• The importance of being “radically inclusive”
• The power of defining something by what it is not
• The creative elegance of the word “as”

So join Professor Patrick Barry as he continues to share lessons from the popular writing course at the University of Michigan on which The Syntax of Sports is based. You’ll learn about language. You’ll learn about advocacy. And …

Automated Chest X-Ray Analysis: Biomedical/Non-Biomedical Foreign Object Detection, Shotabdi Roy

Dissertations and Theses

The presence of non-biomedical foreign objects (NBFO) such as coins, buttons, jewelry, etc. and biomedical foreign objects (BFO) such as medical tubes, and devices in Chest X-Rays (CXRs) make accurate interpretation difficult as they do not indicate known biological abnormalities like excess fluids, Tuberculosis (TB) or cysts. Accurate diagnosis and screening, require these NBFO and BFO to be detected, categorized as either NBFO or BFO, and removed from CXR or highlighted in CXR for effective abnormality analysis. During an automated CXR screening process, NBFOs can adversely impact the process as typical machine learning algorithms would consider these objects to be …

Childhood Interpersonal Trauma And Disordered Eating; The Mediating Role Of Social Information Processing Deficits, Deviated Pubertal Timing, And Emotion, Cazzie Es Steinzor

Dissertations and Theses

Childhood maltreatment has been identified as a risk factor for psychopathology, including disordered eating. The current study tested a transdiagnostic theoretical model, posited by McLaughlin and colleagues (2020), that integrates difficulties with emotions, perceived deviation in pubertal timing, and social information processing deficits to explain the relationship between childhood maltreatment exposure and the development of a range of psychopathology. Specifically, the current study incorporated the aforementioned mechanisms to explain the relationship of child maltreatment with disordered eating. While research supports associations between the aforementioned variables, it is unclear if these three mechanisms better explain the relationship between exposure to childhood …

Identification, Enumeration, And Diversity Determinations For Fungi Enriched On Phthalates As Sole Carbon Source From Riverine Sediments Using Molecular Methods, Anthony M. Vicidomini

All Capstone Projects

Phthalates are a common chemical compound used as plasticizers in various industries that have been linked to several detrimental effects on health. Due to their widespread use, they have become a common environmental pollutant of soil and water. The persistence and distribution of phthalate esters in the environment has given rise to many microorganisms that are able to incorporate phthalates into various metabolic pathways and degrade them into harmless substances, with fungi being among those that are capable of such degradation of industrial polycyclic aromatic hydrocarbons. In this study, the diversity of fungal communities in response to the presence of …

Sacrificing Sisters: Nurses' Psychological Trauma From The First World War, 1914-1918, Kayla Campana

Electronic Theses and Dissertations, 2020-2023

This thesis examines psychological war trauma nurses experienced during the First World War. Psychological war trauma, or shell shock, as it was commonly known during the war, has largely been identified as a male affliction. In this thesis, I demonstrate that women too, suffered trauma and we can better understand nurses' trauma by applying some of the same analytical techniques that scholars have previously used to examine male combatant trauma. Moreover, I analyze the ways in which contemporary actors, including medical professionals and the public, imagined female trauma, specifically the way nurses' psychological trauma could be understood and articulated. Additionally, …

Workers, Mothers, And Françaises: The French Communist Party And Women In The Interwar Period (1920 - 1939), Elizabeth Klements

Electronic Theses and Dissertations, 2020-2023

A survey of the first two decades of the French Communist Party's propaganda reveals a wide range of female imagery, from the androgynous, Soviet-style militant of the 1920s to the fashionable, feminine figure of the 1930s. Earlier scholars noting this discrepancy argued that the Party first adopted the Soviet "new woman," based on the Marxist principle of absolute gender equality but rejected it just over a decade later in order to broaden their appeal to the French masses. These studies, however, were restricted by the limited access to the French Communist Party's interwar-era archives. Using recently-digitized Party meeting records, reports, …

To The Moon And Back: The Impact Of Moon Rocks On The Historical Legacy Of Nasa's Apollo Program, Emily Strickland

Electronic Theses and Dissertations, 2020-2023

Most would say that the pinnacle of the Space Race was when the United States landed on the Moon. Besides the countless videos and images, what is the proof that the U.S. was there? Moon rocks are tangible evidence that the U.S. was on the Moon. Once the moon rocks came to Earth, they were studied, distributed, and displayed. The goal of this research is to examine the displays and narratives of the Apollo lunar samples. Understanding where and how the rocks ended up in their earthly homes around the country allows for analysis of the historical and cultural impacts …

"We're Not Just Well Suited, We Are Ethically Obligated!": Reimagining Technical And Professional Communication Pedagogy As Advocacy Against Discriminatory Digital Technologies, Anshare Antoine

Electronic Theses and Dissertations, 2020-2023

This dissertation expands on scholarship that examines efforts at incorporating a social justice framework into pedagogy, specifically, the role of technical and professional communication (TPC) faculty in addressing discriminatory digital technologies within a social-justice-oriented tech ethics pedagogy. I observe that despite the thousands of computer technology students who graduate from their programs every year in the US with the latest training, there seems to be no change to the adverse tech culture that produces discriminatory and racist work environments and digital technologies. The implication is that computer technology programs may not be prioritizing a tech ethics pedagogy that supports addressing …

Improving Urban Resilience And Sustainability Via Multi-Scale Urban Food-Energy-Water-Waste Nexus Analysis, Andrea Valencia Marin

Electronic Theses and Dissertations, 2020-2023

Urban sustainable development requires an in-depth and holistic understanding of the complex Food-Energy-Water-Waste (FEWW) nexus facing population growth, climate change, economic development, and pollution control. Following the United Nations (UN) 17 Sustainable Development Goals (SDGs), goal 11 aims for sustainable cities and communities to be resilient, sustainable, and safe cities to achieve social, economic, and environmental sustainability. Explicitly, SDG target 11.3 concentrates on inclusive and sustainable urbanization for sustainable planning and management. As the UN Food System program aims for inclusive, sustainable, and resilient network, promoting sustainable food systems becomes a necessity to echo social, economic, and environmental sustainability. The …

Synthesis, Characterization, And Modeling Of Thermo-Responsive Hydrogels With Improved Mechanical Strength And Swelling Kinetics, Marilu Ortiz Nieves

Electronic Theses and Dissertations, 2020-2023

Hydrogels have been extensively studied for use in applications such as tissue engineering, drug delivery systems, wound dressing, actuators, valves, and sensors in Micromechanical Systems (MEMS), among others. Thermo-responsive hydrogels in particular pose various advantages such as their capability to respond to an external stimulus and reverse the response when the stimulus is removed and the ability to imbibe a significant amount of solvent and increase their volume by over 1000%. Extensive research has been conducted to tune and improve hydrogel’s rate and degree of swelling and mechanical properties. Previous work showed that when synthetic clay (Laponite) is cross-linked with …

2022 Fall Commencement, Georgia Southern University

Commencement Programs

No abstract provided.

Multiomic Hypotheses Underlying Behavioral Manipulation Of Camponotus Floridanus Ants By Ophiocordyceps Camponoti-Floridani Fungi, Ian Will

Electronic Theses and Dissertations, 2020-2023

Parasitic manipulation of host behavior lies at the intersection of disease, animal behavior, and coevolutionary processes. In many of these interactions, the underpinning biology is brought into sharp focus as they are obligate relationships, under strong selection to bring about specific changes in host behavior that determine if the parasite will transmit or die. However, experimental and molecular techniques to understand these interactions are still developing and identification of the mechanisms of manipulation is a primary goal in the field. As such, we investigated host-parasite interactions between Camponotus floridanus (Florida carpenter ant) and Ophiocordyceps camponoti-floridani (Florida zombie ant fungus) from …

The Effect Of Audiovisual And Written Interactivity On Teacher-Candidates' Application Of Instructional Support Practices For English Learners In An Online Tesol Course, Sophie Cuocci

Electronic Theses and Dissertations, 2020-2023

With the increased number of English learners in the United States, teacher candidates need to be prepared to address their needs in their future classrooms. Teacher preparation programs around the nation are continuously exploring solutions to better develop teacher candidates' skills. Simultaneously, the rise in popularity of online education has pushed universities to identify and integrate technology tools which best promote students' learning. This study, connecting both challenges, aims to identify which type of interactivity promoted by technology, in an undergraduate online teaching English for speakers of other languages (TESOL) course, most benefits pre-service teachers in their ability to apply …

Commencement Program (Spring 2022), Csusb

CSUSB Commencement Programs

No abstract provided.

Education Law—A Child Left Behind: Exploring Failures In Effective Iep Implementation—Lamar Consol. Indep. Sch. Dist. V. J.T., 577 F. Supp. 3d 599 (S.D. Tex. 2021), Katie Groves

Suffolk Journal of Trial and Appellate Advocacy

No abstract provided.

Small Interfering Rna (Sirna)-Based Therapy, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.

Oregon State Rank Assessment For Cascade Torrent Salamander (Rhyacotriton Cascadae), Eleanor P. Gaines

Institute for Natural Resources Publications

Oregon state conservation status assessment for Cascade torrent salamander (Rhyacotriton cascadae) using NatureServe methodology, 2022

The Private Art Collector’S Foundation In France: Issues And Implications For The Cultural Landscape, Milena Berman

MA Theses

The last two decades have witnessed an explosion in the number of private art spaces worldwide. From Bentonville, Arkansas, to Naoshima, Japan, hundreds of impressive structures built by star architects have been funded by private individuals and corporations to house collections of modern and contemporary art, often in unlikely places. The famously-termed “Bilbao effect” in which a grand museum structure is set up outside of the established art capitals of the world, thus putting the city “on the map” of cultural tourism, has become a widespread trend. The examples vary greatly and range from small private “home museums”
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A Horor Theory For Introspective Consciousness, Adriana Renero, Richard Brown

Publications and Research

Higher-order theories of consciousness typically account for introspection in terms of one’s higher-order thoughts being conscious, which would require a third-order thought—i.e., a thought about a thought about a mental state. In this work, we offer an alternative account of introspection that builds on the recent Higher-Order Representation of a Representation (HOROR) theory of phenomenal consciousness. According to HOROR theory, phenomenal consciousness consists in having the right kind of higher-order representation. We claim that this theory can be extended to introspection by recognizing that there is a distinctive kind of consciousness—i.e., introspective consciousness—which can be accounted for as the theory …

Too Fast? Too Slow? A Novel Approach For Identifying Extreme Response Behavior In Online Surveys, Manasvi Kumar, Joseph S. Valacich, Jeffrey L. Jenkins, David Kim

Faculty Publications

Some participants of online surveys engage in extreme answering behavior while generating responses (i.e., they respond too fast or too slow) relative to population norms. Here, we demonstrate how participants’ navigation behaviors can be used to potentially identify such responses. We administered an online survey where students (who were earlier instructed to complete a task) report lenience scores towards non-appropriate behavior while completing the task. We draw on cognitive dissonance theory to posit that failure to follow instruction predicts lenience scores. We then created different datasets by excluding data from participants flagged by our metrics and generated predictive models. We …