Digital Commons Network^™

Environmental Dna Analysis Of A Critically Endangered Cavefish, Katelyn Giltner

Research Horizons Day Posters

No abstract provided.

Trat Virulence Factor Protects Drug-Resistant Uropathegenic Escherichia Coli Against Serum Killing, Chae Hee Lim, Katelyn Lott, John B. Land, Morgan Welch

Research Horizons Day Posters

No abstract provided.

Piecing Together The Puzzle Of Anxiety And Autism Spectrum Disorder: The Relationship Between Anxiety And Asd (Concept Study), Autumn B. Schreiner

Research Horizons Day Posters

No abstract provided.

Book Review Of The Law Student’S Guide To Doing Well And Being Well, Lawrence Krieger

Journal of Legal Education

No abstract provided.

Scientists To Explore Suicidal Behavior For Brain Awareness Week, Edwin B. Smith

University of Mississippi News

March 23 discussion on Zoom looks at efforts to understand and treat behaviors

Characterization Of Active Electrode Yield For Intracortical Arrays: Awake Versus Anesthesia, Jeffrey R. Capadona

Faculty Scholarship

Intracortical microelectrode arrays are used for recording neural signals at single-unit resolution and are promising tools for studying brain function and developing neuroprosthetics. Research is being done to increase the chronic performance and reliability of these probes, which tend to decrease or fail within several months of implantation. Although recording paradigms vary, studies focused on assessing the reliability and performance of these devices often perform recordings under anesthesia. However, anesthetics—such as isoflurane—are known to alter neural activity and electrophysiologic function. Therefore, we compared the neural recording performance under anesthesia (2% isoflurane) followed by awake conditions for probes implanted in the …

Exploring The Inferiority Model In Adlerian Psychotherapy, Rachel Bradley

Student Works

Alfred Adler once afflicted with inferiority due to organ inferiority, became the founding father of Individual/Adlerian psychology. Adlerian psychotherapy spans numerous contemporary theories in psychology. Adlerian psychotherapy is a holistic, phenomenological, optimistic and socially entrenched theory, on how everyone interprets themselves and others within the society they live (Maniacci & Sackett-Maniacci, 2019). An overview will be provided of where one of Adler’s most important assumptions, inferiority, fits within the Adlerian theory. Given such, the negative responses to inferiority: inferiority complex and superiority complex will be discussed, followed by socially useful type of inferiority. After that, inferiority as a specific element …

Archetypal Legal Scholarship: A Field Guide, 2d. Edition, Martha Minow, Susannah Barton Tobin

Journal of Legal Education

No abstract provided.

Road Salt Effects On Leaf-Level Isoprene Emission, Aarti Mistry

College of Science and Health Theses and Dissertations

Road salt accumulation in the environment influences plants, soils, and surrounding ecosystem. From the use of chloride-based deicers, [Na+] and [Cl-] can be found in leaf tissue and have been shown to affect plant function negatively through reduced photosynthetic activity. Photosynthetic activity is an important plant function that drives plant health and is also linked to isoprene emissions. Certain plant genera emit isoprene, a biogenic volatile organic compound (BVOC) which produces tropospheric ozone and reduces regional air quality. Isoprene is emitted into the atmosphere by photosynthetic activity from leaves. Isoprene emissions from these plants are an indicator of plant health …

Strategic Basic Research: Cognition And Suggestions, Xiaoxuan Li, Xiaoxi Xiao, Zhiyong Lou, Bing Zhu, Zihe Rao

Bulletin of Chinese Academy of Sciences (Chinese Version)

This paper sorts out and clarifies the concept of strategic basic research, and summarizes the international experiences in supporting strategic basic research. On this basis, it analyzes the main problems in supporting strategic basic research in China, such as the lack of top-level design, unclear funding objects, and insufficient sustainable and stable support. Some suggestions are put forward, such as setting up an independent strategic basic research program, taking the national strategic forces as the main forces to organize and implement the strategic basic research program, and establishing a dual-track supporting model that coordinates the directional project funding and the …

Characteristics And Funding Strategies Of Mathematical Research, Xiaoxi Xiao, Xiaoshan Gao, Yaxiang Yuan

Bulletin of Chinese Academy of Sciences (Chinese Version)

Strengthening mathematical research aiming at the national strategic needs and major frontier problems is conducive to promoting mathematics research to play a more important strategic role in national development and international competition. This study analyzes the basic characteristics of mathematical research, summarizes the international experiences in funding mathematical research, and then deeply analyzes the major problems of Chinese funding mechanisms for mathematical research, such as the lack of overall planning, the short of sustainable and stable support, and the urgent need to improve the training, selecting, and funding mechanism for high-level mathematical talents. It also puts forward some policy suggestions, …

Strategic Consideration And Recommendation On Development Of Chemistry In China, Yanlin Cheng, Shuxian Wu, Qing Dai, Chunying Chen, Yuliang Zhao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Chemistry, as a central science linking all the other sciences, has played an influential role in promoting the development of the whole scientific and technological field and the prosperity of economy and society. Developed countries strongly support the development of chemistry and effectively promote the level of chemical research and chemical industry. Since the founding of the People's Republic of China, chemical research has been supported among the field of natural sciences, and its current level is at the forefront of the world. However, there are still problems in the field of chemistry research in China, such as insufficient major …

Research On Characteristics, Development Trend And Funding Countermeasures Of Biology, Jie Chen, Jing Qu, Zhiyong Lou, Bing Zhu, Le Kang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Strengthening the research in biology aimed at national strategic needs and major scientific frontier issues is conducive to giving full play to the strategic supporting role of biological research for national economic development and the promotion of international competitiveness. This article combs the basic characteristics and development trend of biology, summarizes the practical experience of international biological research funding, and analyzes the outstanding problems in biological research in China, such as incomplete layout, lack of sustainable and stable support, and insufficient funding for top talents and teams. By referring to the international practical experience, it puts forward policy suggestions to …

Strategic Development Problems And Mechanism Improvement In Engineering Science, Peinan Li, Weimin Bao, Wei Yao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Modern engineering embodies the characteristics of multi-disciplinary integration and is the engine for the development of basic science and engineering technology. Engineering science comes from engineering and serves engineering. Engineering science and natural science both belong to the category of basic research and are the basis of jointly supporting the development and progress of engineering technology. To this end, this paper reviews the development process of engineering science, and on the basis of fully grasping the and the connotation, development stage and modern characteristics of engineering science, draws on the experience and practices of major countries in the development of …

Origins Of Strategic Basic Research And International Practices, Ruhan A, Kejia Yang, Cong Wu, Xiaoxuan Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

Strategic basic research is a novel concept evolves along with the historical development and understanding of what constitutes as basic research. It evolves from the interactions among different communities and their changing practices, the management and new demand from the government, the changing relationship between public and scientific community and the changes of funding structures for science and technology. This paper first reviews the historical development and understanding of basic research so that to investigate how has the concept of strategic basic research evolved, and then it summarizes the international practices of management and funding of basic research in the …

Development Strategy Of China’S Advanced Material Industry Cluster, Kun Zeng, Xiaopeng Li, Ziyun Shen, Fan Liao, Jinsong Xiao, Qingli Huang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The advanced material industry is a basic and strategic industry of the national economy, as well as the key area of global competition in technology industry. Under the dual-cycle development pattern, propelling the cluster development of advanced material industry has become a key to raise the level of the advanced material industry development. This article described the spatial distribution of the advanced material industry cluster in China, analyzed the characteristics and development stage of the advanced material industrial cluster, and compared the gap between the advanced material industry cluster in China and the world-class advanced manufacturing industry cluster. In addition, …

Development And Implication Of Amorphous Alloys, Weihua Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

The development of metallic materials is closely correlated to the civilization of human being. Amorphous alloys with long-range disordered atomic microstructure, unique physical and mechanical properties, are advanced and novel metallic materials which have diverse industrial applications. Recently, the scientific research, new system development, and industry applications of the structural disordered alloys such as amorphous alloys and high entropy alloy are fast developing, and have significant influence on fields such as the desgin and development of metallic materials, structural materials, green materials, magnetic materials, catalytic materials, and information materials. In this article, we review the history, the development trends, the …

Thoughts And Suggestions On Development Of Earth Sciences In China, Lihua Zhou, Xin Wang, Chengxiong Zhou, Quanyou Liu, Jianhua Si, Wang Zhang, Zhijun Jin

Bulletin of Chinese Academy of Sciences (Chinese Version)

Earth Sciences is a multi-disciplinary science, which takes the interaction of Earth's various spheres and their resources and environmental effects as the research object. As a comprehensive and systematic science that not only expands the frontier of human knowledge but also serves the social and economic development of human beings, Earth Sciences not only studies the past and reveals the evolution history of the Earth, but also faces the future and provides solutions for the sustainable development of human beings. Based on the analysis of the international development trends of Earth Sciences and the summary of the development status and …

Association Between Serum Lycopene And Lung Cancer Mortality: An 18-Year Follow-Up Study Of A National Cohort, Evans Afriyie-Gyawu, Padmini Shankar, Gulzar H. Shah, Alicia A. Brown, Shannon Cearley, Akwasi Ampofo-Yeboah, Nathaniel Abrams, Jian Zhang

Health Policy & Community Health: Faculty Publications

Background: Lycopene is a carotenoid found in some fruits and vegetables that is responsible for the red pigment in tomatoes and tomato products. While many studies have shown a link between lycopene and protection against the initiation and/or progression of lung cancer, data on its effect on lung cancer survivability is limited.

Objective: The primary objective of this study was to see if there was a link between lycopene levels in the blood and lung cancer mortality. A secondary goal was to see if dietary factors influence lycopene levels in the blood.

Materials and Methods: A retrospective …

The Who Global Tuberculosis 2021 Report - Not So Good News And Turning The Tide Back To End Tb, Chakaya Jeremiah, Eskild Petersen, Rebecca Nantanda, Brenda N. Mungai, Giovanni Battista Migliori, Farhana Amanullah, Patrick Lungu, Francine Ntoumi, Nagalingeswaran Kumarasamy

Department of Paediatrics and Child Health

Objective: To review the data presented in the 2021 WHO global TB report and discuss the current constraints in the global response.
Introduction and methods: The WHO global TB reports, consolidate TB data from countries and provide up to date assessment of the global TB epidemic. We reviewed the data presented in the 2021 report.
Results: We noted that the 2021 WHO global TB report presents a rather grim picture on the trajectory of the global epidemic of TB including a stagnation in the annual decline in TB incidence, a decline in TB notifications and an increase in estimated TB …

Oyster Reef-To-Mangrove Regime Shifts Along The West Coast Of Florida, Stephen Gregory Hesterberg

USF Tampa Graduate Theses and Dissertations

Ecological regime shifts are transitions in ecosystem state, which can occur either when external conditions gradually change or when large perturbations force a system into an alternative state. Such transitions can exhibit non-linear dynamics, where small changes in external conditions can result in abrupt transition and often occur with little warning. After crossing a tipping point, the system may be unable to revert to its original state if the new regime possesses strong, reinforcing feedbacks. Numerous marine ecosystems have experienced regime shifts due to a combination of stressors that have eroded ecological resilience, such as overfishing, nutrient loading, and climate …

Wittgenstein And Hume On Miracles, Samuel Wheeler

Undergraduate Research Symposium

In this paper, I intend to contrast the positions of Ludwig Wittgenstein and David Hume on miracles. While Hume holds that miracles are violations of laws of nature which can never be probable, Wittgenstein would reject this definition. Instead, he takes a broader stance on miracles and holds that many events which are not transgressions of laws of nature can be seen as miraculous. And the point of this is to highlight the vastly different events we call miracles. Contra Hume, Wittgenstein thinks that even some of our greatest certainties can call up in us a sense of absolute wonder …

Dignity Norfolk: How One Tidewater Group Enabled Gay And Lesbian Catholics To Form Long Lasting Friendships And Chosen Families, Chelsea Lembert

Undergraduate Research Symposium

In the past decade, research has been conducted to look into the history of the Queer Community of the Tidewater Region. Students and community volunteers have conducted interviews and gathered documents connected to the queer community to grow the study and breadth of available information for future researchers. However, more in-depth knowledge of community connections and familial ties within the queer community in the Tidewater Region was needed. Through research into Our Own Newspaper, local historical background information, and in-person interviews, I pieced together first-hand accounts of life through the eyes of a gay man or lesbian woman living in …

Access To Nitrogen Heterocycles Via Borrowing Hydrogen Catalysis, Robert P. Reynolds, Kellen P. Mcguire, Conor T. Mccormick, Kyle M. Lambert

Undergraduate Research Symposium

Nitrogen heterocycles are ubiquitous motifs which occur as the core structure of several alkaloid natural products exhibiting inherent biological activity against an array of bacteria, fungi, viruses, and cancer cell lines. These azacycles serve as key synthetic building blocks for medicinal chemists to access more structurally complex and diverse compounds with tunable biological properties. A synthetic approach to these valuable motifs employing intramolecular borrowing hydrogen catalysis has been developed. The utility of the developed chemistry will be applied to synthetic efforts towards the recently isolated Cylicomorphins A-E.

Oxidation Of Thiols To Disulfides Using An Environmentally “Green” Organocatalyst And New Mechanistic Insights, Kosta V. Vlasakakis, Olivia M. White, Robert P. Reynolds, Shayne M. Weierbach, Shannon M. Weaver, Ramsey T. Ritter, Nishi H. Patel, Eric C. Hayes, Sydney Dunmire, Kyle M. Lambert

Undergraduate Research Symposium

The selective oxidation of thiols to disulfides is an area of great importance in the areas of materials and medicinal chemistry research. The production of polymers, rubber, pharmaceuticals, and the folding of proteins in biological systems all rely on the formation of disulfide bonds. Herein, we introduce a stoichiometric and electrocatalytic method for the oxidation of various pharmaceutically and biologically relevant thiols into their respective disulfides in more environmentally benign solvents such as water and alcohol solvents. The scope of the transformation was evaluated and a detailed mechanistic study involving control experiments, experimental kinetic studies, and computational investigations led to …

Revisiting The History Of Takayasu Disease: Studies And Surgical Treatment, Shavkat I. Karimov, Akmal A. Irnazarov, Abdurasul A. Yulbarisov, Khojiakbar K. Alidjanov

Central Asian Journal of Medicine

Nonspecific aortoarteritis (Takayasu disease) is a systemic disease belonging to the group of vasculitis, mainly affecting the arteries of the elastic and muscular-elastic types of large and medium caliber with localization of the inflammatory process in the media and adventitia. The article describes the history of the development of ideas about clinical manifestations, morphological changes and the course of the disease from 1761 to the present, the chronology of medical achievements in the study of this disease.

Lectins And Their Application In Forensic Medical Practice, Mukharrama A. Khasanova, Nizom J. Ermatov

Central Asian Journal of Medicine

The problem of obtaining economically cheap drugs for determining the group (in liquid form and in traces) is relevant. Diagnostic lectinology in relation to the determination of the blood group of the AB0 system is currently widely used in many countries of the world. The commercial cost of lectins is tens and even hundreds of times lower than the cost of rabbit absorption serum. The study of lectins in the seeds of some plants growing on the territory of Uzbekistan has shown the possibility of using them in the determination of antigens of the AB0 system.

Serving Students With Disabilities Who Are Culturally And Linguistically Diverse In Rural Communities: Technology Access Is Essential, Benjamin Gallegos, Lisa A. Dieker, Rebecca Smith, Nicole C. Ralston

Northwest Journal of Teacher Education

Before the COVID-19 pandemic changed the educational landscape, students with disabilities, especially those who are culturally and linguistically diverse, and their special education teachers who worked and attended schools located in rural communities faced barriers most schools and communities experienced nationwide. As schools shifted to remote virtual learning due to the COVID-19 pandemic, rural schools were already at a disadvantage with the lack of resources with technology access. The call for addressing shortcomings in the various digital technology supports towards enhancing the teachers’ delivery of content and the students’ academic outcomes has been a continual challenge to address. This paper …

Pharmacologic Ascorbic Acid As Early Therapy For Hospitalized Patients With Covid-19: A Randomized Clinical Trial, Dagan Coppock, Pierre-Christian Violet, Gustavo Vasquez, Katherine Belden, Michael Foster, Bret Mullin, Devon Magee, Isabelle Mikell, Lokesh Shah, Victoria Powers, Brian Curcio, Daniel A. Monti, Mark Levine

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Despite the widespread availability of effective vaccines, new cases of infection with severe acute respiratory syndrome coronavirus-2, the cause of coronavirus disease 2019 (COVID-19), remain a concern in the settings of vaccine hesitancy and vaccine breakthrough. In this randomized, controlled, phase 2 trial, we hypothesized that high-dose ascorbic acid delivered intravenously to achieve pharmacologic concentrations may target the high viral phase of COVID-19 and thus improve early clinical outcomes. Sixty-six patients admitted with COVID-19 and requiring supplemental oxygen were randomized to receive either escalating doses of intravenous ascorbic acid plus standard of care or standard of care alone. The demographic …

Predicting Mitochondrial Dynamic Behavior In Genetically Defined Neurodegenerative Diseases, Gerald W Dorn Ii, Xiawei Dang

Open Access Publications

Mitochondrial dynamics encompass mitochondrial fusion, fission, and movement. Mitochondrial fission and fusion are seemingly ubiquitous, whereas mitochondrial movement is especially important for organelle transport through neuronal axons. Here, we review the roles of different mitochondrial dynamic processes in mitochondrial quantity and quality control, emphasizing their impact on the neurological system in Charcot-Marie-Tooth disease type 2A, amyotrophic lateral sclerosis, Friedrich's ataxia, dominant optic atrophy, and Alzheimer's, Huntington's, and Parkinson's diseases. In addition to mechanisms and concepts, we explore in detail different technical approaches for measuring mitochondrial dynamic dysfunction in vitro, describe how results from tissue culture studies may be applied to …