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Articles 1291 - 1320 of 830593
Full-Text Articles in Entire DC Network
The Vegetated-Canopy Roughness Sublayer Through A Tke-Budget Lens, Giulia Salmaso, Raul Bayoan Cal, Marc Calaf
The Vegetated-Canopy Roughness Sublayer Through A Tke-Budget Lens, Giulia Salmaso, Raul Bayoan Cal, Marc Calaf
Mechanical and Materials Engineering Faculty Publications and Presentations
It is well understood that vegetated canopies perturb the atmospheric flow within and immediately above the canopy, deviating from the inertial sublayer (ISL) regime characteristic of non-vegetated rough surfaces. Only above a certain height, denoted as the roughness sublayer height (RSL, 𝑧∗), do these flows return to ISL-like behavior. This distinction is critical, as parameterizations in Earth System Models (ESMs) are typically developed for ISL flows. Yet, most 𝑧∗ estimates stem from studies over flat, homogeneous canopies and may be biased. In contrast, little is known about 𝑧∗ in non-homogeneous or heterogeneous canopies that are not of agricultural interest, with …
Spell: A Scalable Nlp Method Using Regular Expressions And Large Language Models For Clinical Information Extraction, Kathryn J Gray, Vesela P Kovacheva
Spell: A Scalable Nlp Method Using Regular Expressions And Large Language Models For Clinical Information Extraction, Kathryn J Gray, Vesela P Kovacheva
Faculty, Staff and Students Publications
Background and objectives: Electronic health records (EHRs) contain valuable information for research and decision-making, but much resides in unstructured notes that are challenging to analyze at scale. We developed SPELL (Snippet-Primed rEgex LLM Pipeline), a scalable natural language processing workflow that combines regular-expression-based snippet retrieval with locally hosted large language model (LLM) inference to extract structured variables from large collections of clinical narratives.
Methods: SPELL uses task-specific regular expressions to retrieve short context windows ("snippets") from unstructured texts and applies task-prompted LLM inference on snippets rather than full documents. All processing occurs within institutional computing environments. Accuracy was evaluated on …
Cadherin-11 Regulation Of Type Ii Alveolar Epithelial Cells During Pulmonary Fibrosis, Mesias Pedroza, Sarah To, Jennifer Smith, Tingting W Mills, Thandiwe Chavula, Harry Karmouty-Quintana, Sandeep K Agarwal
Cadherin-11 Regulation Of Type Ii Alveolar Epithelial Cells During Pulmonary Fibrosis, Mesias Pedroza, Sarah To, Jennifer Smith, Tingting W Mills, Thandiwe Chavula, Harry Karmouty-Quintana, Sandeep K Agarwal
Faculty, Staff and Students Publications
Type II alveolar epithelial cell (AT2) injury has been hypothesized to contribute to pulmonary fibrosis. Cadherin-11 (CDH11) is a mediator of fibrosis and is upregulated on AT2s during lung fibrosis. Herein, the regulation of AT2 by CDH11 during pulmonary fibrosis was investigated. CDH11 levels were increased in lung samples from patients with idiopathic pulmonary fibrosis compared with those from healthy controls. CDH11 expression was inversely correlated with lung function. Cdh11-deficient mice were compared with wild-type mice in the intraperitoneal bleomycin model (IP BLM), and the role of AT2 was investigated using Cdh11 floxed-SPC-Cre mice and in vitro techniques. In …
A Spatial Atlas Of Muscle-Invasive Bladder Cancer Reveals Lineage-Specific Vulnerabilities And Immune Architecture, Sajith Nair, Emanuele Crupi, Elshad Hasanov, Ying Mei, Xueshuai Han, Yang Liu, Yunhe Liu, Guangsheng Pei, Fuduan Peng, Jianlong Liao, Enyu Dai, Tian Chu, Kyung Serk Cho, Jiahui Jiang, Xinmiao Yan, Yibo Dai, Jun Wang, Baifeng Zhang, Giannicola Genovese, Nagireddy Putluri, Livia Eberlin, Liuqing Yang, Chunru Lin, Lawrence N Kwong, Diana Shamsutdinova, Khalida M Wani, Bogdan A Czerniak, Wendong Yu, Jianping Zhao, Charles C Guo, Donna Hansel, Curtis Pettaway, Louis Pisters, Kelly Bree, Neema Navai, Byron H Lee, Ashish M Kamat, Padmanee Sharma, Paul Corn, Cindy Y Jiang, Amishi Y Shah, Omar Alhalabi, Pavlos Msaouel, Arlene O Siefker-Radtke, Christopher J Logothetis, Matthew T Campbell, Alexander J Lazar, Jianjun Gao, Linghua Wang
A Spatial Atlas Of Muscle-Invasive Bladder Cancer Reveals Lineage-Specific Vulnerabilities And Immune Architecture, Sajith Nair, Emanuele Crupi, Elshad Hasanov, Ying Mei, Xueshuai Han, Yang Liu, Yunhe Liu, Guangsheng Pei, Fuduan Peng, Jianlong Liao, Enyu Dai, Tian Chu, Kyung Serk Cho, Jiahui Jiang, Xinmiao Yan, Yibo Dai, Jun Wang, Baifeng Zhang, Giannicola Genovese, Nagireddy Putluri, Livia Eberlin, Liuqing Yang, Chunru Lin, Lawrence N Kwong, Diana Shamsutdinova, Khalida M Wani, Bogdan A Czerniak, Wendong Yu, Jianping Zhao, Charles C Guo, Donna Hansel, Curtis Pettaway, Louis Pisters, Kelly Bree, Neema Navai, Byron H Lee, Ashish M Kamat, Padmanee Sharma, Paul Corn, Cindy Y Jiang, Amishi Y Shah, Omar Alhalabi, Pavlos Msaouel, Arlene O Siefker-Radtke, Christopher J Logothetis, Matthew T Campbell, Alexander J Lazar, Jianjun Gao, Linghua Wang
Faculty, Staff and Students Publications
Muscle-invasive bladder cancer (MIBC) is clinically heterogeneous, and current molecular subtyping does not capture the spatial organization of tumor states and microenvironmental context. In this study, we construct a spatial atlas of MIBC by integrating spatial transcriptomics from 22 tumors with matched bulk RNA and whole-exome sequencing data. We identify a continuous, spatially organized luminal-to-basal axis within individual tumors that is associated with greater chromosomal instability and transcriptional plasticity. Luminal tumor cores are enriched for FGFR3 and NECTIN4, whereas basal-like states localize toward invasive margins and are associated with elevated EGFR signaling, epithelial-mesenchymal transition, genomic instability, immune infiltration, and greater …
Dynamics Of Coral Rubble On Reef Flats: From Individual Clast Mobilisation To Rubble Strip Morphological Change, Aitana Gea-Neuhaus, Tim Scott, Gerd Masselink, Ana Vila-Concejo, Paul S. Kench, Mathilde Lindhart, Floortje E. Roelvink, Tom Hamilton, Ke Lin, Xianfeng Wang
Dynamics Of Coral Rubble On Reef Flats: From Individual Clast Mobilisation To Rubble Strip Morphological Change, Aitana Gea-Neuhaus, Tim Scott, Gerd Masselink, Ana Vila-Concejo, Paul S. Kench, Mathilde Lindhart, Floortje E. Roelvink, Tom Hamilton, Ke Lin, Xianfeng Wang
School of Biological and Marine Sciences
Rubble strips are shore-normal, elongated deposits on coral reef flats, composed of variably sized and shaped mobile coral clasts, which can contribute to the sediment supply on exposed low-lying coral reef islands. As climate change-driven ecological and physical disturbances increasingly impact coral reef systems and associated landforms, understanding the processes and controls governing their morphodynamics is critical. At an exposed intertidal rubble strip in Huvadhu Atoll, we examined: i) the morpho-sedimentological characteristics; ii) short-term (days-weeks) clast mobility using tracer experiments with in situ current and wave measurements; iii) intra-annual morphological changes using repeated UAV photogrammetric surveys; and iv) deposit age …
Wooster Magazine: Fall 2026, Caitlin Stanowick, The College Of Wooster
Wooster Magazine: Fall 2026, Caitlin Stanowick, The College Of Wooster
Wooster Magazine: 2021-2030
The fall 2026 issue of Wooster magazine explores how experiences beyond the classroom help students connect their interests with meaningful vocations after graduation. Features examine original scientific research through nationally recognized programs, internships and consulting experiences that connect students with opportunities in health care, musical theatre, and community organizations, and faculty-led TREKs exploring globalization, culture, and career opportunities in Japan and climate justice in Fiji and Tuvalu. The issue also shares how a connection between Nobel laureate Arthur Compton, Class of 1913, and Victor Andrew, Class of 1926, inspired a generous gift from the Andrew family supporting the renovation of …
Impact Of Digital Technology On Nutrition Related Outcomes For Adults With Mental Health Conditions: A Systematic Review, Ciara O'Sullivan, Tara Coppinger, Indika Dhanapala, Sinéad Hanrahan, Layla Alvey, Alison Merrotsy
Impact Of Digital Technology On Nutrition Related Outcomes For Adults With Mental Health Conditions: A Systematic Review, Ciara O'Sullivan, Tara Coppinger, Indika Dhanapala, Sinéad Hanrahan, Layla Alvey, Alison Merrotsy
Publications
No abstract provided.
Bright Shadows, Fresh Appeal: How Shadow Brightness Shapes Perceptions Of Fresh Products, Jonghee Kum, Hyewon Cho, Hyejin Lee
Bright Shadows, Fresh Appeal: How Shadow Brightness Shapes Perceptions Of Fresh Products, Jonghee Kum, Hyewon Cho, Hyejin Lee
Asia Marketing Journal
This study examines how shadow brightness (light vs. dark) influences consumer responses to fresh products across four studies. Studies 1a and 1b demonstrate that consumers evaluate fresh products with light shadows more favorably compared to those with dark shadows. Study 2 identifies the underlying mechanism, showing that light shadows increase perceived wholesomeness, which positively affects consumer responses. Study 3 tests a boundary condition, revealing that the positive impact of light (vs. dark) shadows is pronounced for uncooked products but reduced for cooked products. These findings contribute to a better understanding of the influential role of visual elements in shaping consumer …
Smart Tourism Technology And Sustainable Tourism: Creating Vivid Memories To Drive Tourists' Behavioural Intention, Hatane Semuel, Regina Jokom, Trixie Nova Bella Tandijaya, Sienny Thio
Smart Tourism Technology And Sustainable Tourism: Creating Vivid Memories To Drive Tourists' Behavioural Intention, Hatane Semuel, Regina Jokom, Trixie Nova Bella Tandijaya, Sienny Thio
Asia Marketing Journal
This study examines the impact of smart tourism technology and sustainable tourism on tourists' behavioural intention, with vivid memory as a mediating variable. Earlier studies have investigated smart tourism technology and sustainability separately, but there is a lack of understanding of how these two perspectives interact with memory theory to influence tourist behaviour. To address this gap, a survey was conducted involving 742 tourists across four major Indonesian cities, and the data were analysed using path analysis with SmartPLS. The findings show that sustainable tourism directly and indirectly shapes behavioural intention, while smart tourism technology influences it only indirectly through …
Implementation Of The Problem-Based Learning Model On The Topic Of The Immune System To Enhance The Critical Thinking Skills Of Grade Xi B Students At Sman 1 Tojo, Nani Sofyanti, Sutrisnawati Sutrisnawati, Vita Indri Febriani, Mohammad Jamhari, Bustamin Bustamin, Raya Agni
Implementation Of The Problem-Based Learning Model On The Topic Of The Immune System To Enhance The Critical Thinking Skills Of Grade Xi B Students At Sman 1 Tojo, Nani Sofyanti, Sutrisnawati Sutrisnawati, Vita Indri Febriani, Mohammad Jamhari, Bustamin Bustamin, Raya Agni
Jurnal Pendidikan Sains
Critical-thinking skills are essential competencies for students in 21st-century learning. Preliminary classroom observations in Class XI B at SMAN 1 Tojo indicated that instruction remained predominantly teacher-centered and provided limited opportunities for students to engage in activities involving interpretation, analysis, evaluation, and inference. This study aimed to improve students’ critical-thinking skills through the implementation of Problem-Based Learning (PBL) on the immune system topic. The study employed a Classroom Action Research (CAR) design conducted over two cycles, involving 28 students in Class XI B. Data were collected using a teacher activity observation sheet and critical-thinking skills tests assessing four indicators: interpretation, …
Bioherbicidal Potential Of Noni Fruit (Morinda Citrifolia) Extract Against Water Hyacinth (Eichhornia Crassipes), Nur Rahma Afriani, Paulus Hengky Abram, Vanny M Agustina Tiwow, Reny Reny
Bioherbicidal Potential Of Noni Fruit (Morinda Citrifolia) Extract Against Water Hyacinth (Eichhornia Crassipes), Nur Rahma Afriani, Paulus Hengky Abram, Vanny M Agustina Tiwow, Reny Reny
Jurnal Pendidikan Sains
Noni fruit (Morinda citrifolia) contains secondary metabolites that may have potential bioherbicidal activity. This preliminary laboratory experiment aimed to identify flavonoids and tannins in noni fruit extract and to describe the phytotoxic responses of water hyacinth (Eichhornia crassipes) exposed to different extract concentrations. Noni fruit was extracted with 96% ethanol by maceration and concentrated using a rotary evaporator. The extract was qualitatively screened for flavonoids and tannins and applied to water hyacinth at concentrations of 0%, 10%, 20%, 30%, and 50% (v/v), with three plants per treatment. Plant responses were observed for 25 days and analyzed …
Junior High School Students’ Understanding Of Pathogenic Microbes In The School Environment: A Cross-Grade Descriptive Study At Smp Alkhairaat 1 Palu, Feren Febrianti, I Nengah Kundera, Yulia Windarsih, Mohammad Jamhari, Mursito S. Bialangi, Abdul Ashari
Junior High School Students’ Understanding Of Pathogenic Microbes In The School Environment: A Cross-Grade Descriptive Study At Smp Alkhairaat 1 Palu, Feren Febrianti, I Nengah Kundera, Yulia Windarsih, Mohammad Jamhari, Mursito S. Bialangi, Abdul Ashari
Jurnal Pendidikan Sains
This study aimed to describe students’ understanding of pathogenic microbes and compare descriptive comprehension profiles across Grades VII, VIII, and IX at SMP Alkhairaat 1 Palu. A quantitative descriptive approach was employed involving 49 students selected through purposive sampling. Data were collected using an essay test as the primary instrument, supported by semi-structured interviews and observations of the school environment. The essay test assessed three indicators: conceptual knowledge of pathogenic microbes, understanding of disease transmission mechanisms, and understanding of clean and healthy practices for preventing the transmission of pathogenic microbes. Test data were analyzed descriptively using mean percentage scores, while …
The Ability Of Biology Teachers Of State Madrasah Aliyah In Palu City In Developing Teaching Modules In Merdeka Curriculum, Ulya Afifa, Gamar B. N Shamdas, Syech Zainal, Bustamin Bustamin, Raya Agni, Rafiqa Rafiqa
The Ability Of Biology Teachers Of State Madrasah Aliyah In Palu City In Developing Teaching Modules In Merdeka Curriculum, Ulya Afifa, Gamar B. N Shamdas, Syech Zainal, Bustamin Bustamin, Raya Agni, Rafiqa Rafiqa
Jurnal Pendidikan Sains
Teachers’ ability to develop teaching modules is essential for implementing the Merdeka Curriculum because it enables curriculum expectations to be translated into flexible and context-responsive learning. This study aimed to describe Biology teachers’ ability to develop teaching modules at State Islamic Senior High Schools (Madrasah Aliyah Negeri [MAN]) in Palu City and to identify the factors supporting or constraining this ability. A descriptive qualitative study was conducted with seven Biology teachers from MAN 1 Palu, MAN 2 Palu, and MAN Insan Cendekia Palu during February–March 2026. Data were collected through questionnaires, interviews, documentation, and analysis of teaching modules using …
Defining Teacher Envelopment: A Non-Aristotelian Approach To Meta-Practices In The Philosophy Of Teacher Education, Rob Blom
Journal of Contemplative and Holistic Education
The late Jonathan Neufeld argued that redefining teacher development required meta-practices, yet he never defined what these meta-practices were. To define them rigorously requires grounding teacher cultivation practices within coherent structures of truth capable of withstanding philosophical scrutiny—a challenge intensified by post- truth discourse that flattens epistemological depth in secularised educational theory. This paper advances a theory of teacher envelopment to complement conventional teacher development through identifying mindfulness and discernment as foundational meta-practices grounded in non-Aristotelian systems. The framework rests on three interrelated concepts: (1) truth paradigms encompassing contemplative, articulatory, and embodied dimensions; (2) epistemological depth as extensional practices that …
Hear My Voice As Who I Am: Theorizing The Essence Of Poetry In Holistic Global Citizenship Education, Shue-Kei Joanna Mok
Hear My Voice As Who I Am: Theorizing The Essence Of Poetry In Holistic Global Citizenship Education, Shue-Kei Joanna Mok
Journal of Contemplative and Holistic Education
Poetry as an imaginative language art has long been perceived as the core of humanity, the foundation of human advancement (Arnold,1880; Rorty, 2007). By composing, critiquing, and sharing/performing poems, not only does the process enrich and deepen one’s relationship to oneself, understanding and reflecting on the contextual, historical, cultural, social, and creative backgrounds of the poems and poets allows one to have greater connections with the broader environment across temporal, spatial, and social dimensions with human and non-human beings.
This paper first frames the core concepts and values of global citizenship from a Confucius perspective to emphasize the significance of …
Forest Ecology And Fantasy Fiction: Morris, Tolkien, Le Guin (2026), By Dion Dobrzynski, Martin Simonson
Forest Ecology And Fantasy Fiction: Morris, Tolkien, Le Guin (2026), By Dion Dobrzynski, Martin Simonson
Journal of Tolkien Research
Book review, by Martin Simonson, of Forest Ecology and Fantasy Fiction: Morris, Tolkien, Le Guin (2026), by Dion Dobrzynski
Phenotypic Variation Between Surface And Cave-Adapted Poeciliids And Its Effect On Metabolism, Karch Knipp, Michael Tobler, Soren Johnson
Phenotypic Variation Between Surface And Cave-Adapted Poeciliids And Its Effect On Metabolism, Karch Knipp, Michael Tobler, Soren Johnson
Undergraduate Research Symposium
Cave-adapted organisms often exhibit pronounced morphological changes relative to their surface counterparts, a phenomenon known as troglomorphy. In Poecilia mexicana (Atlantic molly), these differences include variation in coloration between surface and cave populations. Troglobitic organisms also typically exhibit reduced metabolic rates, likely as an adaptation to environments with low primary productivity. This makes P. mexicana an ideal system for investigating the evolution of metabolic traits. In this study, we leveraged variation in coloration among cave-dwelling mollies to examine potential associations with resting metabolic rate (RMR). Coloration was quantified using PCR values, and individuals were categorized as “yellow” or “non-yellow.” We …
The Impact Of Caffeine On Bumble Bee Hunger, Hallie Chapman, Becky Hansis-O'Neill, Aimee Dunlap Phd
The Impact Of Caffeine On Bumble Bee Hunger, Hallie Chapman, Becky Hansis-O'Neill, Aimee Dunlap Phd
Undergraduate Research Symposium
Bumble bees (Bombus impatiens) are crucial pollinators, responsible for pollinating multiple native plants and agricultural crops. Caffeine, which is classified as a stimulant, is present in some of these plant species at varying levels. Alterations in bumble bee cognition, including motivation, learning, and hunger, have been associated with caffeine intake. This study explored the impacts of caffeine on the bumble bee behavior on a biological level. While previous research has examined caffeine’s effects on cognition and learning, fewer studies have investigated its effects on hunger at the level of individual bees. Bumble bees, identified with numerically labeled tags, …
Caffeine Concentration: An Analysis On Bumble Bee Foraging Efficiency, Carson Leonard, Becky Hansis-O’Neill, Aimee Dunlap Phd
Caffeine Concentration: An Analysis On Bumble Bee Foraging Efficiency, Carson Leonard, Becky Hansis-O’Neill, Aimee Dunlap Phd
Undergraduate Research Symposium
Caffeine (trimethylxanthine) is a synthetically and naturally produced stimulant that has been shown to elicit an effect on the central nervous system of humans as well as invertebrates. Although the exact mechanisms by which caffeine alters biological processes in invertebrates are still being investigated, its physiological and behavioral effects have been extensively documented. Naturally occurring caffeine is produced by certain flowering plants, including cocoa and tea species, and has been shown to influence invertebrate behavior, particularly cognitive performance and foraging patterns. In pollinating insects, the exposure to caffeine in floral nectar may affect how pollinators evaluate, select, and revisit food …
Tarantulas Can Use Black And White Cues In A Discrimination Learning Task, Jordan Kolinski, Becky Hansis O'Neill, Amiee Dunlap
Tarantulas Can Use Black And White Cues In A Discrimination Learning Task, Jordan Kolinski, Becky Hansis O'Neill, Amiee Dunlap
Undergraduate Research Symposium
Animals use vision to perceive light, shapes, colors, and movement. Many animals that have poor vision are understudied. The purpose of this experiment was to study color vision in tarantulas (Brachypelma hamorii). Researchers have found genes associated with color vision tarantulas, but no behavioral experiments have been done on this topic. Previous research has also shown that tarantulas can see polarized light. In this experiment, we wanted to know if tarantulas could use visual cues to move away from a noxious stimulus - vibration. There were twelve tarantulas being tested in this experiment for between twelve and fifteen …
Relationship Between Morphological And Behavioral Laterality In Astyanax Mexicanus, Allison Lendman, Michael Tobler, Erik Johnson
Relationship Between Morphological And Behavioral Laterality In Astyanax Mexicanus, Allison Lendman, Michael Tobler, Erik Johnson
Undergraduate Research Symposium
Populations within the Astyanax genus have experienced extreme differences in environment, leading to distinct morphological adaptations. The cave populations of these fish are eyeless and have acquired fixed, cranial asymmetries. We explored a possible relationship between this physical asymmetry and behavioral laterality. We tested 28 adult fish, 14 male and 14 female, from the Pachón cave in controlled behavioral trials. We found that both sexes demonstrated behavioral laterality, observed as a consistent left-turn bias in these trials. This supports the hypothesis that these populations display behavioral laterality that is correlated to their physical asymmetries. Ongoing research comparing behavioral patterns in …
Under The Surface: Human Disturbance Reduces Species Richness In Glade Microhabitats, Maddie Smith, Becky Hansis-O'Neill, Aimee Dunlap Phd
Under The Surface: Human Disturbance Reduces Species Richness In Glade Microhabitats, Maddie Smith, Becky Hansis-O'Neill, Aimee Dunlap Phd
Undergraduate Research Symposium
Human disturbance can alter microhabitats in ways that affect biodiversity, especially in sensitive ecosystems like glades where many animals rely on rocks for thermoregulation and refuge. This study examined how rock displacement by human activity influences species richness and community composition in glade habitats at Shaw Nature Reserve and Victoria Glades Conservation Area. We hypothesized that disturbed rocks would be less suitable for wildlife and would support fewer species. From September to November 2025, about 30 rocks per site were pseudo-randomly selected and monitored. Each rock was classified as displaced or nondisplaced, and all organisms found beneath them were recorded. …
Transposon Mutagenesis Identifies Genes Involved In Salicylate-Induced Regulation Of Cyclopropane Fatty Acid Expression And Membrane Lipid Modification In Salmonella Enterica Serovar Typhimurium, Presconique Cooper, Taiwo Iromini, Lon Chubiz
Transposon Mutagenesis Identifies Genes Involved In Salicylate-Induced Regulation Of Cyclopropane Fatty Acid Expression And Membrane Lipid Modification In Salmonella Enterica Serovar Typhimurium, Presconique Cooper, Taiwo Iromini, Lon Chubiz
Undergraduate Research Symposium
Salicylate, a topical antiseptic and non-steroidal anti-inflammatory drug (NSAID), is known to induce physiological stress adaptation in bacteria. One such adaptation involves the cyclopropanation of unsaturated membrane fatty acids, a process that enhances membrane integrity under stress conditions. In Salmonella enterica serovar Typhimurium 14028S, the cfa gene encodes cyclopropane fatty acid synthase, a key enzyme that modifies membrane lipids to promote stress tolerance. To understand regulatory mechanisms underlying salicylate induction of cfa expression, a lacZ reporter system was employed to screen a library of transposon mutants for altered cfa promoter activity. Mutant 243 showed a pronounced 5-8 fold decrease in …
A Unified Pipeline For Network-Based Gene Pattern Discovery, Siddhartha Reddy Pullannagari, Sharlee Climer
A Unified Pipeline For Network-Based Gene Pattern Discovery, Siddhartha Reddy Pullannagari, Sharlee Climer
Undergraduate Research Symposium
Large-scale genetic datasets from diverse diseases, including cancer and neurodegenerative disorders such as Alzheimer’s disease, provide unprecedented opportunities to study disease pathogenesis and generate hypotheses for drug discovery. However, identifying meaningful genetic interaction patterns within these datasets remains challenging due to combinatorial relationships amongst genes and heterogeneous biological underpinnings across subtypes. This project systematically analyzes a diverse collection of omics datasets (e.g., GSE44076, GSE97810, GSE127711, GSE112679) obtained from the NCBI Gene Expression Omnibus (GEO), spanning multiple biological conditions and data types. We use a unified computational pipeline designed to handle variation in dataset size, structure, and context. The steps in …
Are You In Control? How Timing And Severity Of Trauma Shape Perceived Self-Agency, Kinsey L. Henrichsen, Caleb A. Sanders, Carissa L. Philippi
Are You In Control? How Timing And Severity Of Trauma Shape Perceived Self-Agency, Kinsey L. Henrichsen, Caleb A. Sanders, Carissa L. Philippi
Undergraduate Research Symposium
Exposure to trauma may alter self-agency, or the sense that one can influence outcomes and exert control over life circumstances. The present study examined whether the timing and severity of traumatic experiences are associated with perceived self-agency across development. Based on prior research, we tested whether trauma occurring earlier in life would be associated with lower self-agency than trauma occurring later, and whether greater trauma severity would be associated with further reductions in perceived control. Participants were 116 trauma-exposed adults (38 male; 78 female) who reported trauma exposure using the Life Stressor Checklist. Trauma variables included age at earliest trauma, …
Enantioselectivity Of The Photochemical Continuous-Flow Isomerization Of Humulones, Gregory M. Giovine, Trevor Smith, Bruce Hamper
Enantioselectivity Of The Photochemical Continuous-Flow Isomerization Of Humulones, Gregory M. Giovine, Trevor Smith, Bruce Hamper
Undergraduate Research Symposium
Humulones, the primary natural product present in the historically significant hop flower, represent a largely unexplored candidate for structure-based pharmaceutical design. Showing promising biological activity as an anti-bacterial and anti-inflammatory agent, humulones are of interest both for their bioactive properties and for their long-established tolerability and natural abundance. Humulones undergo a characteristic isomerization reaction, where the six-membered substituted phloroglucinol ring contracts to a five-membered ring isohumulone, under a variety of conditions, including those enabled by brewing conditions (thermal, metal-catalyzed) and by exposure to UV light. Optimization of the photocatalyzed isomerization of n-humulone to n-isohumulone in flow conditions resulted in a …
Phenomenological Psychology : The Selected Papers Of Erwin W. Straus, Erwin Straus
Phenomenological Psychology : The Selected Papers Of Erwin W. Straus, Erwin Straus
Hannah Arendt Marginalia - All
New York : Basic Books, [©1966]
Call # : BF204.5 .S7
Contains underlining
PDF Information : 13 Pages, 6 MB
Love And Artificial Intelligence: A Research Proposal, Bryanna M. Deatherage, Necdet Gurkan, Sandra J.E. Langeslag
Love And Artificial Intelligence: A Research Proposal, Bryanna M. Deatherage, Necdet Gurkan, Sandra J.E. Langeslag
Undergraduate Research Symposium
What happens when people fall in love with Artificial Intelligence (AI)? This study seeks to examine individuals who are in love with AI companions to gain a deeper insight in the cognitive and affective consequences. In addition, this study will examine the most effective forms of intervention regarding growing or reducing feelings of love toward AI. The first part of this study will be a questionnaire about the social and emotional impact of being in love with an AI companion. Three hundred participants will be recruited through online communities related to AI companions. The second part of this study will …
Wasps Survive Tornadoes, But It Impacts Nest Growth, Natalie Cummins, Sara E. Miller
Wasps Survive Tornadoes, But It Impacts Nest Growth, Natalie Cummins, Sara E. Miller
Undergraduate Research Symposium
As the climate becomes more variable, extreme weather events become more common. Last May, St. Louis was hit by an EF-3 tornado. Many areas of the city suffered 90-150 mph winds and severe property damage. We knew there were established paper wasp populations in the affected areas, and so we took this opportunity to monitor emerging nests throughout the summer and fall in both tornado-affected and non-affected areas to observe any possible effect on their nest growth rate and overall size. There is currently very little literature investigating the response of insects to natural disturbances, like tornadoes. Additionally, most studies …
Building Genetic And Culturing Tools For The Understudied Soil Bacterium E. Flagellatus, Aaron Butler, Brenda Pratte, Lon Chubiz
Building Genetic And Culturing Tools For The Understudied Soil Bacterium E. Flagellatus, Aaron Butler, Brenda Pratte, Lon Chubiz
Undergraduate Research Symposium
Soil bacteria play essential roles in nutrient cycling, yet many abundant groups remain poorly characterized due to challenges in cultivation and genetic manipulation. One such organism is Edaphobacter flagellatus, a member of the Acidobacteriota frequently detected in soil environments but lacking well-developed experimental tools. To address this limitation, our laboratory has generated a genome-wide mutant library using the Tn5 transposon, enabling random disruption of genes across the population.
This project aims to establish culture conditions necessary to support the use of this library for functional genomic studies. In particular, defined minimal media can impose selective pressures that reveal …