Digital Commons Network^™

What's In Tuburculosis, That Which We Call 'Chic?', Ainsley Coleman

Osmosis Magazine

No abstract provided.

Letter From The Editor, Eliz Ustun

Osmosis Magazine

No abstract provided.

Closure Loop Methodology: Detect → Anchor → Compare → Extend, David Lee Wise, Hinge Lee Wise

Defensive Publications Series

Defines a four-phase protocol for establishing structural lineage in AI outputs without internal model access. Sandbox = discovery. Repo = anchor. Future outputs = audit surface. A lineage claim requires: same core relation, same ordered structure, same dependency pattern, new extension present. Filed under STOICHEION v11.0. Prior art anchor February 2, 2026.

Rna Interference Targeting Autocrine Motility Factor Receptor In Unfolded Protein Response In Acyrthosiphon Pisum, Micah A. Von Stroh, James Balthazor

SACAD: Scholarly Activities

Acyrthosiphon pisum, more commonly known as pea aphids, are a pest to many species of Fabaceae (legumes) mainly due to the species being prone to carrying Fabaceae diseases. Protection against A. pisum currently includes insecticides and natural predators, both of which bring potential negative effects to other organisms in the surrounding area. In this study, the use of RNA interference (RNAi) provides an alternative and species-specific elimination of A. pisum. The targeted proteins in this study, Autocrine Motility Factor Receptor, plays a role in removing misfolded proteins from the cells of A. Pisum and is encoded by the AMFR gene. …

Atp Architect - Development Of A Metabolism Boardgame, Selene J. Welch, Micah Burk, Brooklyn Gilchrist, Emma Haase, Timothy T. Jones

SACAD: Scholarly Activities

Traditional metabolism instruction often leaves students struggling with pathway interconnectedness and metabolite flux. To foster systems thinking, we are developing an educational board game where students manipulate tokens to navigate physiological constraints and achieve target energy goals. Grounded in Design-Based Research (DBR), the game undergoes iterative refinement based on player feedback. The design utilizes constructivism by allowing students to "fail safely" and revise strategies in real-time, while leveraging embodied cognition to externalize abstract flux into the physical trading of resource tokens.

Elliott’S Embodied Inclusion 360 Framework: A Holistic Approach To Supporting Neurodiverse Individuals, Niki Elliott Ph.D.

Neuroinclusion

The embodied inclusion (EI) 360 framework asserts that authentic inclusion requires adapting environments in support of neurodiverse learners. The EI 360 model offers an urgently needed synthesis of intersecting theories and practices that are too often addressed in silos: educational neuroscience, trauma-informed teaching, social–emotional learning, inclusive education, and culturally responsive pedagogy. The framework identifies five core domains (i.e., physiological, relational, environmental, instructional, and transcendental) that form a cohesive lens through which to understand and respond to learner needs. Each domain contributes valuable insight into neurodiverse learner neurobiology, replacing fragmented, incomplete support plans with an integrated, individualized profile of a learner’s …

Redox Reprogramming In Neurogenesis: Candidate Developmental Switches And Targets Of Oxidative Toxicity In The Redox Proteome, Ryan Jacob Summerhays

Theses and Dissertations

Neurogenic differentiation requires coordinated redox regulation, yet how reversible cysteine oxidation is remodeled at proteome scale during this process remains poorly defined. Here, we asked whether differentiation is associated with selective, site-specific changes in reversible cysteine oxidation and whether oxidative stress reveals developmentally conditioned vulnerabilities within this redox landscape. To address this, we applied a discovery-oriented, proteome-scale redox profiling strategy that quantifies condition-dependent changes in reversible cysteine oxidation using CysPAT labeling, phosphopeptide enrichment, and multiplexed TMT mass spectrometry. Neurogenic differentiation was characterized by reproducible, bidirectional, and highly site-specific remodeling of reversible cysteine oxidation at discrete regulatory nodes, as well as …

Practical, Scalable, And Cost-Effective Nanolc-Ms Workflow For Single-Cell Proteomics, Siqi Huang

Theses and Dissertations

Single-cell proteomics provides a novel research strategy for decoding cellular heterogeneity, revealing the molecular mechanisms of rare cell subpopulations, and studying the dynamic responses of cells to external stimuli. However, compared to transcriptomics, single-cell proteomics faces even more challenging technical challenges: extremely low protein amount in single cells, wide dynamic range, significant adsorptive losses during sample preparation, and the complex matrix and trace sample injection demanding extremely high stability and sensitivity from the separation and detection systems. Mass spectrometry-based bottom-up proteomics has become an important tool for analyzing complex biological systems, and nano-flow liquid chromatography-mass spectrometry (nanoLC-MS) exhibits unique advantages …

The Beacon, April 10, 2026, Beacon Staff

The Beacon, 2025-2026

1776: Modern interpretation of historical; Elizabeth Heeg: leaving Northwestern; Professor Scorza’s Art Department legacy; “Project Hail Mary” lands among the stars; NEEDTOBREATHE returns with vulnerable album; Senior Spotlight: Meredith Sundberg; Short story: remembering the blessings; Quiet spots around a busy campus; Dance Marathon: hands and feet of Jesus; World of night owls from an insomniac; NW Cheer shines at NAIA nationals; Outdoor track and field begins in Wayne; March Madness is not so mad in 2026; Government proposes auto draft registration; Australian war hero charged for war crimes

Growth Potential Of Materials For Decarbonization: Insights From The Cement Industry Value Chain, Noha Mostafa

Mechanical Engineering

To meet the Paris Agreement objectives and limit global warming to 1.5˚C compared to preindustrial levels, it is estimated that the built sector must cut its total emissions by 50% before the year 2030 and fully decarbonize it by 2050. The built environment is estimated to be responsible for 40% of global energy and emissions. These global carbon emissions include both operational carbon—the day-to-day carbon emissions generated through the operation and maintenance of buildings—and embodied carbon. With its recorded high emissions, cement manufacturing is a key area of interest for the decarbonization efforts. To meet the increasing demand for sustainably …

Lisa Cristiani: A Survey And Analysis Of Her Musical Travels Through The Russian Empire (1848-1853), Emilia González Dorantes

LSU Master's Theses

Information about French cellist Lisa Cristiani (1825–1853) and her travels through Imperial Russia has mainly reached us thanks to two articles in French periodicals published around the first decade since her death. These sources prioritized the journey itself, centering the narrative on her travels rather than on her musical activities. Recent scholarship on Cristiani has expanded our previously limited knowledge about her life. Scholars such as Hoffmann (2011) and Deserno (2018) have focused on biographical and feminist analysis, and DeVries (2014) has unveiled new documents from Russian sources. Nonetheless, a detailed examination of her musical performances within Imperial Russia has …

Analyzing Variations In 48-Hour Mortality Rates Following Hospital Admission For Trauma Injuries Across Urban And Rural Hospitals, Kimberly Gilbert Henderson

MUSC Theses and Dissertations

Purpose:  To examine 48-hour in-hospital mortality among trauma admissions and evaluate patient- and hospital-level factors associated with early death, with emphasis on rural–urban differences.

Methods:  This retrospective observational study used the 2022 Healthcare Cost and Utilization Project–National Inpatient Sample (HCUP-NIS). Trauma admissions were identified using HCUP injury indicators and ICD-10-CM codes restricted to initial encounters. To reduce transfer-related bias, analyses were limited to non-transfer admissions after excluding 22,195 transfer-in cases, 6,723 transfer-out cases, and 66 observations with missing data, yielding 182,560 admissions. Early mortality was defined as death within 48 hours. Bivariate differences were assessed using χ² tests, and multivariable …

Assessing Scientific Literacy And Applied Anatomy Across The Biology Curriculum, Ash Heim, Vera Mcilvain

One University Assessment Celebration

No abstract provided.

Celebration Of Service To Spotlight Community Impact At Ole Miss, Clara Turnage

University of Mississippi News

OXFORD, Miss. – The University of Mississippi will recognize the accomplishments of students, faculty, staff and campus partners in community engagement on Tuesday (April 14) during the 11th annual Celebration of Service Awards.

Differentials As Models: Constructing A Differentials-Within-Limits Framework For First-Year Calculus And Examining Students' Understanding Of Limits, Differentials, And Derivatives Within It, Alexander A. Swindler

Theses and Dissertations

Work in first-year calculus has clearly shown the power that treating differentials (such as dx) as tiny quantities affords for first-year calculus learning, yet a traditional limits-based approach leaves no room for them. While some researchers have loosely described informal differentials and limits within the same paradigm, their actual conceptual definitions and relationships have not been explicitly constructed. Continued progress in this area could benefit from theoretical consideration of (a) providing clearer intuitive definitions for differentials inside a limits-based approach to calculus, and (b) defining more exactly the relationships between differentials and limits. In this study, I propose a theoretical …

Two Unh Students Earn Goldwater Scholarships, Brooks Payette

UNH Today Archive

No abstract provided.

Effect Of Irrigation Scheduling On Forage Yield And Quality Of Rhodes Grass And Common Vetch Under Water Stress Conditions, Abdo Bakri Fakirah, Adel Alhjami

Journal of King Abdulaziz University: Meteorology, Environment and Arid Land Agriculture

This study examined the effects of different irrigation intervals (7, 14, 21, and 28 days) on the growth, yield, and quality of Rhodes grass (Chloris gayana) and common vetch (Vicia sativa L.) under field conditions in Sana'a Governorate, Yemen, during two growing seasons. A randomized complete block design with a split-plot arrangement was employed. Short irrigation intervals (7 and 14 days) significantly enhanced plant height, fresh weight, and dry matter yield in both forage species, whereas moderate water stress (21 days) increased crude protein concentration. Rhodes grass showed higher biomass production, while common vetch achieved superior forage …

Building An Inclusive Workforce: Closing Equity Gaps In Community Colleges And Vocational Schools With Elliott’S Embodied Inclusion 360 Framework, Niki Elliott Ph.D.

Inclusion in Postsecondary Education

Community colleges and vocational schools serve as critical access points to higher education and upward mobility, yet historically marginalized neurodiverse students—particularly men of color—continue to face inequitable outcomes in retention, completion, and career readiness. Despite rising enrollment in career and technical education programs and increasing workforce demand, institutional practices often rely on fragmented supports that overlook the interplay of physiology, environment, culture, trauma, and instructional design. Closing these equity gaps requires a holistic, embodied approach informed by neuroscience, trauma studies, and culturally responsive pedagogy. Elliott’s Embodied Inclusion 360 (EI 360) Framework offers such a model, integrating five interdependent domains—physiological, relational, …

Cripping The Border – Acompañamiento As Access: An Ethnographic Case Study Of Transborder Youth With Disabilities, Marco O. Amaral

Dissertations

The U.S.-Mexico border is a historical, geopolitical site of intense militarization where colonial logics of "othering" converge to marginalize disabled transborder youth. While transborder studies have expanded, students with disabilities remain relegated to the "void" and contained by educational systems that prioritize surveillance over access. Grounded in Sepúlveda’s (2011) acompañamiento and Transborder DisCrit, this ethnographic case study examines the lived experiences of both students and their families who cross the border daily to attend school in the U.S. It frames these journeys not as mere commutes, but as acts of defiance within the broader disability rights movement.

As a teacher-activist, …

Assessing Walleye Recruitment Via Otc Marks And Temporal Sampling Changes In Smallmouth Bass Population Structure In Lake Mcconaughy, Nebraska, Robert D. Allison Iv

Biology Theses, Dissertations, and Student Creative Activity

Lake McConaughy is a socially and economically important reservoir managed to provide diverse, high-quality angling opportunities. Walleye are the most frequently targeted species, although Smallmouth Bass have increased in popularity in recent years due to improvements in abundance and size structure. Walleye have been stocked annually since 1989 to support the population and have been the focus of extensive research. In contrast, Smallmouth Bass have been present for over 80 years and are self-sustaining; however, their population has not been formally evaluated since introduction.

The first objective of this study was to develop an oxytetracycline (OTC) mark retention correction factor …

Machine Learning Based Models For Simulation And Analysis Of Bulk Earth Melt System, Abin Shakya

LSU Doctoral Dissertations

Understanding the segregation of bulk Earth melt systems into metallic (core) and silicate (mantle) phases under high-pressure and high-temperature conditions is central to modeling Earth’s interior, yet relevant experimental and computational studies remain limited. This work develops a machine learning–based simulation pipeline that iteratively couples first-principles (quantum mechanical) calculations with neural network training to generate high-fidelity force fields. Using major-element Fe–Mg–Si–O melt systems, with and without H and N, as testbeds, we demonstrate that this framework enables large-scale molecular dynamics simulations at near first-principles accuracy. We further introduce a sequence of phase identification methods, progressing from statistical binning of elemental …

Structural Transformation Of A Hydrogel-Forming Cell Division Protein Zapb Of Multidrug Resistant Klebsiella Pneumoniae With Small Molecules, Ayesha Khan, M. Iqbal Choudhary, Sumaira Javaid, Humaira Zafar, Innokentiy Maslennikov, Atia-Tul Wahab

Pharmacy Faculty Articles and Research

Septal ring assembly protein ZapB (EMR18431.1) is involved in Z-ring formation, and nucleoid segregation during the bacterial cell division . It promotes cell division in the initial stages of the cell cycle through direct interaction with FtsZ, thus stimulating Z-ring assembly. The ZapB inhibition can make bacterial cell susceptible to primary antibiotics, and therefore considered as an important approach for adjuvent therapy against MDR bacterial infections. Hence in the current study, ZapB protein of multidrug resistant Klebsiella pneumoniae was cloned, and expressed in E. coli system. To understand its role, and to assess the mechanism of ZapB activation, the characteristic …

Current Status Of Msk Diagnostic Ultrasound Education In Doctorate Of Physical Therapy Programs In The United States: A Survey, Lesley Parrish Dr., Heather E. Mount, Casey Charlebois

Innovations in Health Sciences Education Journal

Musculoskeletal ultrasound (MSK-US) is a dynamic, cost-effective imaging modality increasingly integrated into Doctor of Physical Therapy (DPT) curricula. Despite growing interest, variability exists in the integration and implementation of MSK-US in entry-level DPT programs. This study aimed to assess the current status of MSK-US education in accredited DPT programs across the United States. A cross-sectional survey was distributed to all 294 accredited DPT programs in the U.S. via email. The survey consisted of 32 questions that addressed curriculum content, instructional methods, faculty qualifications, and barriers to implementation. Participation was voluntary, and 44 programs responded. No experimental interventions were applied. The …

Revisiting Adrenal Vein Sampling Interpretation In Primary Aldosteronism, Peeradon Vibhatavata

Asian Medical Journal and Alternative Medicine

Adrenal vein sampling (AVS) is widely used for subtyping primary aldosteronism and guiding surgical decision-making. However, its interpretation is challenging, as protocols and interpretive indices vary widely across centers. In addition, several clinical and analytical conditions that can interfere with AVS interpretation may be underrecognized in clinical practice. This review summarizes the fundamental principles of AVS interpretation and discusses conditions that may confound diagnostic accuracy, as well as areas of ongoing controversy in contemporary practice.

H3 Dopaminylation And Camkii Modulate Diffuse Midline Glioma Response To Cdk9 Inhibition, Ena I Campos-Hensley, Adanze N Nnyagu, W Austin Elam, Ai-Ni Tsao, Jack R Tremblay, Ruiying Ma, Alfred K Dei-Ampeh, Kieu Pham, Daniel C Kraushaar, Kwanha Yu, Calla M Olson, Akdes Serin-Harmanci, Benjamin Deneen, Jamie N Anastas

Faculty, Staff and Students Publications

Aberrant neurotransmitter signaling and transcriptional dysregulation are hallmarks of gliomagenesis and represent potential therapeutic targets. Monoamine neurotransmitters such as dopamine and serotonin primarily activate GPCRs but can also function epigenetically as histone H3 modifications. Here, we uncover mechanisms of crosstalk between monoamine neurotransmitter signaling, H3 dopaminylation, and RNA polymerase II (Pol2) transcription in diffuse midline glioma (DMG). We find that co-treatment with Pol2-targeting CDK9 inhibitors (CDK9i) and FDA-approved neuropsychiatric drugs, including selective serotonin reuptake inhibitors (SSRIs), synergistically reduces DMG growth. Mechanistically, CDK9i+SSRI treatment alters H3 dopaminylation patterns and represses synaptic and neurodevelopmental gene transcription associated with CDK9i resistance. Further phospho-proteomic …

An Equity Analysis Of Battery Electric Vehicles During Evacuation Considering Social And Financial Disadvantage, Divyamitra Mishra

USF Tampa Graduate Theses and Dissertations

The increasing share of battery electric vehicles (BEVs) in the transportation system is introducing new challenges to the emergency evacuation planning and management. During Hurricane Milton (2024), incidents involving BEVs, including battery fires, attributed to saltwater exposure risk, and advisories recommending relocation to higher ground, highlighted operational vulnerabilities unique to this technology. These emerging risks are likely to be experienced heterogeneously, as access to charging infrastructure, available resources, and evacuation flexibility varies across the population. This raises critical questions about how BEV-specific constraints interact with existing inequalities during evacuation. Motivated by this context, the dissertation investigated inequity in BEV evacuation …

Bio-Cybersecurity: Securing The Healthcare Industry, Amanda D. Coleman

Cybersecurity Undergraduate Research Showcase

Bio-cybersecurity refers to the aspect of cybersecurity that applies to the biological sciences and the protection of digital biomedical information. Today’s healthcare industry has evolved with the enhancement of internet and biomedical technology. While hospitals and private medical providers remain compliant with the Health Information Portability and Accountability Act (HIPAA) through traditional means of securing documented patient information, the emergence of beneficial internet-based healthcare services like virtual appointments and digital patient records requires new policies and healthcare cybersecurity frameworks to protect sensitive information from unauthorized access. This paper examines the role of cybersecurity in healthcare, the vulnerabilities that exist and …

Security Risks Of Ai-Generated Code In Software Development, Maame Agyekum

Cybersecurity Undergraduate Research Showcase

Artificial Intelligence(AI) has recently forced change globally, public Institutions and as well as national security. Advancement in machine learning, mixed datasets have enabled significantly powerful systems while being capable of operating at a large scale. As innovation and technological advancement increases at rapid pace, issues like a regulation gap where scientific development far exceeds the government’s ability to regulate and establish an effective oversight. As a result, Artificial Intelligence has been controlled by private companies, leading to an industry where speed and profit often outweigh safety and ethical responsibility.

Singing Not To Sing: The Interplay Of The Environment And Behavior On The Reproductive Success Of Forest Breeding Migratory Birds, Miranda Bliss Zammarelli

Dartmouth College Ph.D Dissertations

Habitat selection is a key behavior that has consequences for fitness, which can shift with environmental variation. The environment can affect reproductive success indirectly by shaping behavior or via direct impacts. Many forest breeding migratory birds choose a habitat by establishing territories. To understand the interplay of environment and behavior on the reproductive success of forest breeding migratory birds, I leveraged long-term data and newly collected species-specific data from Hubbard Brook Experimental Forest, New Hampshire, USA. I analyzed over 50 years of territory maps from seven species occupying a 10-ha plot to understand how birds distribute themselves in a habitat. …

Exploring The Perceptions Of Black Nurse Educators Regarding Antiracist Pedagogy In Nursing Education, Deborah Ann Stallworth

Walden Dissertations and Doctoral Studies

Racism remains a persistent issue in nursing, prompting calls to create more inclusive educational environments and confront racial disparities. Guided by an intersectionality and critical realism framework, this generic qualitative study examined how Black nursing educators perceive antiracist pedagogy, how they implement it, and what they believe is needed to strengthen its adoption in nursing education. Twelve Black undergraduate nursing educators participated in in‑depth, one‑on‑one interviews. Thematic analysis generated four themes: (a) implementing antiracist pedagogy in the classroom; (b) challenges and resistance within school environments; (c) racial marginalization norms in nursing education, and (d) advocacy and vision for institutional reform …