Digital Commons Network^™

Our Hbcus Matter: Factors Influencing Hbcus’ Graduation Rates, Brandon Markelle Graham

Tennessee State University Alumni Theses and Dissertations

This qualitative comparative multi case study examined how institutional practices, leadership philosophies, and academic support systems affect Pell Grant recipients' student success at Atlantic A&M University (AAMU) and Heritage State University (HSU). Based on Swail's Geometric Model of Student Persistence and Achievement, the study examined cognitive, institutional, and social factors of student success using institutional data, NCES datasets, and two former HBCU presidents' perspectives. Semi-structured interviews with former tenured HBCU presidents illuminated how financial constraints, performance-based accountability metrics, and admissions standards shaped campus strategies from 2012 to 2021. The study examined first-time, first-year Pell Grant recipients' graduation outcomes, standardized test …

Evaluating Safety Assurance Of Ai Classifiers Trained On Systematically Generated Sar Imagery, Branndon Jones

Tennessee State University Alumni Theses and Dissertations

The collection and curation of high-quality data is crucial for developing robust and trustworthy deep learning (DL) models. Due to the costly and time-consuming nature of gathering well-annotated data, researchers have shifted to supplementing network training with synthetic data. However, when solely training AI classifiers with synthetic data, the network performance when exposed to data from real environments may not be satisfactory. To mitigate this shortcoming, a Gen-AI model was developed to systematically generate annotated, context-controlled synthetic imagery datasets using real SAR imagery. Through this process, SAR images of targets of interests are initially semantically segmented and introduced onto the …

Application Of High-Pressure Processing And Real-Time Pcr For Preventing Foodborne Bacterial Diseases, Ranju Kafle

Tennessee State University Alumni Theses and Dissertations

Foodborne pathogens pose significant risks to public health and food safety, necessitating innovative control strategies. High-pressure processing (HPP) was evaluated as an intervention against Listeria monocytogenes in cold-smoked rainbow trout, with treatments at 500 MPa and 4.4 °C and 60.0 °C achieving up to a 5.03 log CFU/g reduction. The efficacy of nisin in suppressing Listeria monocytogenes and Listeria innocua during refrigerated storage was also examined, demonstrating significant microbial inhibition, particularly in the early storage phase, supporting its application as a hurdle technology. Additionally, the synergistic effects of HPP (400 MPa, 4 °C) and natural bioactive compounds, including lactic acid, …

Mutation Of Smarca4 Induces Cancer Cell-Intrinsic Defects In The Enhancer Landscape And Resistance To Immunotherapy, Yawen Wang, Ismail M Meraz, Md Qudratullah, Sasikumar Kotagiri, Yanyan Han, Yuanxin Xi, Jing Wang, Kadir C Akdemir, Jack A Roth, Yonathan Lissanu

Faculty, Staff and Student Publications

Cancer genomic studies have identified frequent alterations in genes encoding components of the SWI/SNF chromatin remodeling complex, including SMARCA4 and ARID1A. Importantly, clinical reports indicate that SMARCA4-mutant lung cancers respond poorly to immunotherapy and have dismal prognosis. In this study, we corroborated the clinical findings by using immune-humanized, syngeneic, and genetically engineered mouse models of lung cancer harboring SMARCA4 deficiency. Specifically, models with SMARCA4 loss showed decreased response to anti-PD-1 immunotherapy associated with significantly reduced infiltration of dendritic cells and CD4+ T cells into the tumor microenvironment. SMARCA4 loss in tumor cells led to profound downregulation of STING1, IL1β, and …

Cisplatin Palbociclib Combination Differentially Modulates Pten Akt Signaling Via Hsp90 In Hepatocellular Carcinoma Cells., Eman Ramadan

Pharmacy

Hepatocellular carcinoma (HCC) presents a significant global health challenge, marked by high mortality and recurrence. This study investigated the synergistic potential of cisplatin and palbociclib (C + P) against HCC cell lines. RT-qPCR revealed that C + P significantly downregulated HCC-related genes, including Hsp90, β-catenin, and components of the PI3K/AKT/mTOR pathway, compared to cisplatin alone and controls. Western blotting confirmed a reduction in phosphorylated AKT (P-AKT) with palbociclib and C + P, while PTEN, a tumor suppressor, was upregulated in the C + P group. Annexin V-FITC assays demonstrated a substantial increase in apoptosis in palbociclib and C + P …

Unh Police Sergeant Balances The Badge And The Books, Aaron Sanborn

UNH Today Archive

No abstract provided.

From Lists To Infinite Scroll: A Comparative Analysis Of Youtube’S Two Recommendation Algorithms, Selimhan Dagtas

Theses and Dissertations

As social media platforms increasingly dominate information consumption, the role of recommendation algorithms in determining user experience has grown both in complexity and impact. This thesis investigates the behavioral patterns and algorithmic preferences embedded within YouTube’s recommendation systems, comparing long- form videos with the rapidly growing category of short-form content, YouTube Shorts. Through a combination of automated data collection, engagement metric analysis, emotional sentiment detection, and toxicity assessment, this study analyzes the evolution of content over successive recommendation depths. Using a controlled digital environment, the research explores how content recommendations change in response to user behavior, including varying watch times …

Rule-Mediated Connectivity In Social-Ecological-Technological Systems: A Comparative Network Analysis Of Reservoir Operation Rules In Coyote Valley Dam (United States) And Ameghino Dam (Argentina), Tomás Olivier, Hoon C. Shin, David J. Yu, Margaret Garcia

Center for Policy Design and Governance

This brief summarizes "Rule-mediated connectivity in social-ecological-technological systems: A comparative network analysis of reservoir operation rules in Coyote Valley Dam (United States) and Ameghino Dam (Argentina)," co-authored by Tomás Olivier, Hoon C. Shin, David J. Yu, and Margaret Garcia in the Journal of Environmental Management.

Measuring Emotional Intelligence With The Msceit 2: Theory, Rationale, And Initial Findings, John D. Mayer, David R. Caruso, Peter Salovey, Iris Y. Lin, Braden J. Hansma, Joanna Solomon, Gill Sitarenios, Manolo Romero Escobar

UNH Personality Lab

Introduction: The model of emotional intelligence as an ability has evolved since its introduction 35 years ago. The revised model includes that emotional intelligence (EI) is a broad intelligence within the Cattell-Horn-Carroll (CHC) model of intelligence, and that more areas of problem solving are involved than originally detailed. An argument is made here that veridical scoring of EI test responses is a sound procedure relative to scoring keys based on expert consensus or a single emotion theory. To the degree that EI fits present-day theories of intelligence (i.e., the CHC model), any subsidiary factors of EI reasoning should correlate highly …

Social Exclusion And Mental Health Of Youths Affected By Parental Hiv/Aids In China: Based On A Serial Mediating Model, Jiaojiao Wan, Lili Ji, Zheqian Wang, Junfeng Zhao, Xiaoming Li

Faculty Publications

The mental health of youth living with patients with HIV needs focused attention. The primary source of psychological distress they experience may stem from social exclusion. Therefore, the current study was designed to explore the relationship between social exclusion and mental health among youths affected by parental HIV/AIDS in rural China.

Methods

297 youths affected by parental HIV/AIDS were recruited to completed questionnaires of social exclusion, perceived stress, future orientation and mental health. The bootstrap method was used to examine the mediation effects.

Results

It showed that: (1) the social exclusion (M = 32.48, SD = 15.25) significantly and …

Intouch Week Of June 2, 2025, New York Medical College

InTouch

• NYMC Celebrates the Class of 2025 at 166th Commencement
• SOM Awards Ceremony Honors Excellence
• SHSP Dean’s Awards Recognize Rising Health Leaders
• GSBMS Honors Excellence in Biomedical Science at Annual Awards Ceremony
• TCDM Celebrates the Class of 2025
• Noninvasive Method for Early Intraventricular Hemorrhage Detection in Preemies Revealed

Development Of A Low-Cost Electron Microscope For Educational Purposes, Christopher Halseth

Dissertations and Theses

Electron microscopy is a powerful tool for exploring microscopic world, yet its high cost and operational complexity severely limit accessibility, particularly within educational institutions. Commercial systems are often designed as opaque "black boxes," further hindering hands-on learning and experimentation. This dissertation introduces the Educational Scanning/Transmission Electron Microscope (EduSEM), a project designed to overcome these barriers by developing a low-cost, modular, and transparent electron microscope optimized for educational use.

The EduSEM achieves significant cost reduction by operating in a rough vacuum environment (1-20 mTorr), eliminating the need for expensive high-vacuum pumps. This necessitates novel component designs tolerant of higher pressures. The …

Accessibility To Public Spaces: Intersections Between The Courts And The Houseless Community, Margaret Maxey

Dissertations and Theses

In an attempt to answer the question of what role the judiciary played in affecting access to public spaces from the 1960's to 2024, this thesis identifies an accumulation of patterns relating to the courts' role in accessibility of public parks and their amenities over this time period. The data supplied for this question is drawn from scholars focusing on judicial decisions and political theory relating to public spaces, including those mentioned above. The result of this study will include a close examination of the role the judiciary holds as a cornerstone institution in not only our democracy, but in …

Iron Deficiency Without Anemia And Reduced Basal Ganglia Iron Content In Youths, Dimitri Fiani, Joo-Won Kim, Mianzhi Hu, Ramiro Salas, Sarah Heilbronner, Jacquelyn Powers, Muhammad Haque, Stephanie Dinh, Xiaofan Huang, Darrell Worthy, Sridevi Devaraj, Junqian Xu, Chadi Calarge

Faculty, Staff and Students Publications

Importance: Although brain iron is necessary for neurogenesis, myelination, and neurotransmitter synthesis, iron deficiency (ID) is defined solely based on hematological outcomes.

Objective: To examine the association of ID without anemia with basal ganglia (BG) iron content and its structural and functional sequelae in adolescents.

Design, setting, and participants: This cross-sectional study enrolled participants using the electronic medical record system from a large network of pediatrics clinics between December 2020 and April 2024. Otherwise healthy, unmedicated participants aged 10 to 17 years with a depressive or anxiety disorder or with no psychopathology were consecutively enrolled. Anemia and acute inflammation led …

Hudson Shore Associates Limited Partnership, Haven On The Hudson Llc, Kenneth Levinson, And Hudson Valley Property Owners Association Et Al. V. State Of New York, New York State Division Of Housing And Community Renewal, Village Of Nyack, New York, And City Of Poughkeepsie, New York

All Decisions

Landlords challenged New York's Vacancy Provisions, alleging Fourth Amendment violations for warrantless searches of rent rolls and Fourteenth Amendment due process violations concerning vacancy calculations. The court affirmed dismissal, holding that Article 78 proceedings provide sufficient pre-compliance review for record demands, and the low risk of coercion mitigates Fourth Amendment concerns. Due process was satisfied by opportunities for landlords to contest vacancy calculations through public hearings and subsequent Article 78 review, ensuring constitutional muster.

Gnss Technology, Utah State University Space Dynamics Laboratory

Space Dynamics Laboratory Publications

SDL presentation on GNSS Technology

Impact Of An Adapted Diabetes Prevention Program In A Spanish Primary Care Setting: Protocol For A Type Ii Hybrid Effectiveness-Implementation Cluster-Randomized Trial (Aladim), Miquel Bennasar-Veny, Manuela Abbate, Miquel Colom-Rosselló, Laura Capitán-Moyano, Ivonne C Hernández-Bermúdez, Ignacio Ricci-Cabello, Aina M Yañez, Maria E Fernandez

Faculty, Staff and Student Publications

Background: Type 2 diabetes (T2D) is a global health concern affecting 10.5% of the adult population and is projected to rise significantly in the coming decades. Lifestyle modification programs, such as the Diabetes Prevention Program (DPP), can effectively reduce T2D risk among individuals with prediabetes. However, their implementation in real-world healthcare settings remains poor, particularly in Spain, where T2D prevalence is the highest in Europe. The ALADIM study aims to evaluate the effectiveness and implementation of an adapted DPP in Spanish Primary Care Centers (PCCs). The primary effectiveness outcome is weight, the co-primary implementation outcome is implementation fidelity. We will …

Exploring Soft Polymeric Nanoparticles For Targeted Biomolecule Delivery In Plant Cells, Mohammad Rashid

Theses and Dissertations

Safe and efficient agricultural practices require innovative technologies. Nanotechnology offers promising solutions for advancing plant agriculture by enabling the targeted delivery of biomolecules such as agrochemicals and nucleic acids. This study focuses on developing a safe nanotechnological approach for delivering molecules of interest into plant cells. We investigated the ability of four types of polymeric nanoparticles such as Polyethylene glycol N, Nʹ-dibutylethylenediamine (PEG-DB), Polyethylene glycol 2-pyrrolidin-1-yl-ethyl-amine (PEG-PY), Polyethyleneimine (PEI), Arabinoxylan (AX)+, and Zein+ to form conjugates with plasmid DNA (pDNA). Our findings confirm that plant-derived cationic nanopolymers, AX+ and Zein+, effectively bind negatively charged pDNA (pGFPGUSPlus) carrying a GFP reporter …

Longitudinal Outcomes Of The Covid-19 Pandemic On Youth Physical Fitness, Andjelka Pavlovic, David Leonard, Timothy J Walker, Derek W Craig, Jizyah Injil, Laura F Defina

Faculty, Staff and Student Publications

Importance: The COVID-19 pandemic led to a decline in physical activity levels among youths, which could have a negative impact on their fitness.

Objective: To examine longitudinal changes in cardiorespiratory fitness (CRF) and musculoskeletal fitness (MSF) among students at schools participating in a school-based physical activity program during fall 2019 through spring 2023.

Design, setting, and participants: This longitudinal cohort study included US schools reporting CRF and MSF data at least once during the pandemic (fall 2020 to fall 2021) and at least 1 additional time before or after. In a subset of schools for which learning modality data was …

Cytarabine Pharmacogenomics And Outcomes Among Children And Young Adults With Acute Myeloid Leukemia., Richard J. Marrero, Vivek M. Shastri, Deedra Nicolet, Krzysztof Mrózek, Christopher J. Walker, William G. Blum, Bayard L. Powell, Jonathan E. Kolitz, Joseph O. Moore, Geoffrey L. Uy, Wendy Stock, Andrew J. Carroll, John C. Byrd, Richard Aplenc, Todd M. Cooper, Alan S. Gamis, Huiyun Wu, Stanley Pounds, Yi-Cheng Wang, Todd A. Alonzo, Soheil Meshinchi, Ann-Kathrin Eisfeld, Edward A. Kolb, Jatinder K. Lamba

Manuscripts, Articles, Book Chapters and Other Papers

IMPORTANCE: Therapeutic responses in acute myeloid leukemia (AML) demonstrate considerable variability both across and within established risk stratifications and age groups. Moreover, significant racial disparities persist, with Black patients experiencing inferior survival outcomes compared with their White counterparts.

OBJECTIVE: To validate the association of the previously reported 10 single nucleotide variant (SNV)-based ara-C pharmacogenomics score (ACS10) with survival outcomes in a large cohort of pediatric AML patients; to evaluate whether ACS10 remains relevant in an adolescent and young adult (AYA) population of patients with AML treated with similar intensive induction chemotherapy protocols; and to assess the association of ACS10 with …

Teacher Perceptions On The Low Enrollment Of Students Of Color In High School Computer Science, Wiley J. Cruse, Jr.

Walden Dissertations and Doctoral Studies

The rapid evolution of computer science (CS) as an integral part of K-12 public education in the United States has highlighted significant equity and diversity issues. Guided by critical race theory and community cultural wealth, this basic qualitative study explored high school CS teachers’ perceptions of the challenges and opportunities related to recruiting, retaining, and ensuring the success of students of color. Thematic analysis of data collected using semistructured interviews with 12 high school CS teachers revealed key challenges, including curriculum rigidity, funding inequities, and lack of administrative support. Participants reported that systemic barriers limit access to CS education for …

Lived Experiences Of Sex Offenders On Probation With Housing And Employment, Katheryn Winslow

Walden Dissertations and Doctoral Studies

Lived Experiences of Sex Offenders on Probation with Housing and Employment by Katheryn Winslow MA, South University, 2013 BS, University of Central Florida, 2010 Dissertation Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy Psychology Walden University May 2025

Staff Education To Improve Nurses’ Knowledge On Medication Administration Error Prevention, Francoise Tabe

Walden Dissertations and Doctoral Studies

This staff education project aimed to enhance nurses’ knowledge on medication administration error prevention through targeted education interventions. Medication administration errors are a significant concern in health care, leading to patient harm and reduced quality of care. This project addressed the gap in nursing knowledge regarding strategies to prevent these errors, with the goal of improving patient safety and outcomes. The practice-focused question explored in this project was the following: How does implementing an education program affect nurses’ knowledge and practices related to medication error prevention? The purpose of this doctoral project was to educate nurses on best practices for …

The Effects Of Post Activation Potentiation Using Accommodating Resistance, Brennan Sweet

Doctorate in Kinesiology

Post activation potentiation is the short increase of power output following a heavy exercise. This effect could be due to several mechanisms, the most popular are increased sensitivity of actin and myosin to calcium or alpha motoneuron reactivity. The idea behind using the accommodating resistance is that eccentrics get lighter throughout the movement to avoid sticking points whilst changing the strength curve of the exercise. This may cause a greater stretch reflex and create more force from the weakest position of the movement because of the eccentrics being quicker also known as. Using accommodating resistance may also be less fatiguing …

Biswal Na Paggiromdom Bilang Porma Ki Pagtumang Sa Historikal Na Kalingawan: Sarong Pagtino Kan Obra Ni Victor Cris Silva Na Saod: The Fading Glimpse, Jaime Jesus Uy Borlagdan

Katipunan

Isinusulong ni Borlagdan sa kaniyang pagsusuri ng pintang Saod: The Fading Glimpse (2019) ni Victor Cris Silva kung paanong nakapaghahain ng kontra-memorya ang likhang-sining sa gitna ng katotohanan ng paglimot na nangyayari sa iba’t ibang bahagi ng bansa. Matatagpuan sa Alumni Hall ng Tabaco National High School, inaalala ng pinta ni Silva ang pampublikong palengke ng Lungsod ng Tabaco na nasunog noong 2003 upang mapalitan lamang ng isa na namang mall. Pinagaaralan ni Borlagdan kung paanong nakikiisa ang pinta ni Silva sa paglikha ng isang ekolohiya ng gunita na nagmumula sa mga maralita at ordinaryong mamamayan. Hindi rito isang layaw …

Suppression Of Brca1 Facilitates Kidney Regeneration, Kaira A Church, Xunian Zhou, Raghu Kalluri

Faculty, Staff and Student Publications

Maladaptive repair following kidney injury leads to the development of kidney disease. In this issue of JEM, Ajay et al. (https://doi.org/10.1084/jem.20231107) uncover the role of breast cancer susceptibility gene 1 (BRCA1) in cell cycle arrest, DNA damage, and cell senescence, preventing maladaptive repair.

"Opting Out Of Ai”: Exploring Perceptions, Reasons, And Concerns Behind Faculty Resistance To Generative Ai, Aya Shata

Hank Greenspun School of Journalism and Media Studies Faculty Research

Research on Generative Artificial Intelligence (GAI) in higher education primarily focuses on faculty use and experiences, with limited attention given to why some abstain from using it. Drawing from Innovation Resistance Theory, this study aims to address this gap by exploring the perceptions of both faculty users and non-users of GAI, identifying the reasons and concerns why they avoid GAI. A survey of 294 full-time higher education faculty from two mid-size U.S. public universities was conducted. Using qualitative and quantitative analysis, results show that over one-third of the faculty members opted out of using GAI for five primary reasons: not …

Drosha: A New Tumor Suppressor In Pineoblastoma, Zhixuan Huang, Xueli Ren, Jian Hu

Faculty, Staff and Student Publications

In this Outlook, Huang et al. discuss a study in this issue of Genes & Development by Fraire et al. that shows that a deficiency in miRNA processors Drosha and Dicer and consequent cell cycle gene derepression promote pineoblastoma development. The authors highlight the heterogeneity of pineoblastoma's pathogenic mechanisms and its implications for therapeutic interventions in the clinic.

Hyaluronan Network Remodeling By Zeb1 And Itih2 Enhances The Motility And Invasiveness Of Cancer Cells, Sieun Lee, Jihye Park, Seongran Cho, Eun Ju Kim, Seonyeong Oh, Younseo Lee, Sungsoo Park, Keunsoo Kang, Dong Hoon Shin, Song Yi Ko, Jonathan M Kurie, Young-Ho Ahn

Faculty, Staff and Student Publications

Hyaluronan (HA) in the extracellular matrix promotes epithelial-mesenchymal transition (EMT) and metastasis; however, the mechanism by which the HA network constructed by cancer cells regulates cancer progression and metastasis in the tumor microenvironment (TME) remains largely unknown. In this study, inter-α-trypsin inhibitor heavy chain 2 (ITIH2), an HA-binding protein, was confirmed to be secreted from mesenchymal-like lung cancer cells when cocultured with cancer-associated fibroblasts. ITIH2 expression is transcriptionally upregulated by the EMT-inducing transcription factor ZEB1, along with HA synthase 2 (HAS2), which positively correlates with ZEB1 expression. Depletion of ITIH2 and HAS2 reduced HA matrix formation and the migration and …

A Comprehensive, Multi-Center, Immunogenomic Analysis Of Melanoma Brain Metastases, Lucy Boyce Kennedy, Amanda E D Van Swearingen, Marissa R Lee, Layne W Rogers, Alexander B Sibley, Jeff Sheng, Dadong Zhang, Xiaodi Qin, Eric S Lipp, Swaminathan Kumar, Aron Joon, Pixu Shi, Michael A Davies, Kouros Owzar, Carey K Anders, April K S Salama

Faculty, Staff and Student Publications

Background: Melanoma brain metastases (MBM) have a unique molecular profile compared to extracranial metastases (ECM). Description of the biological features and clinical outcomes of MBM will facilitate the design of rational therapies.

Methods: We examined the mutational landscape and gene expression profiles of MBM (74 patients) and ECM (34 patients) in paired patient samples from a previously published dataset with whole-exome sequencing (WES) and RNA sequencing (RNAseq) data from MD Anderson Cancer Center (MDACC). We also present findings from MBM from a new cohort of 14 patients from Duke University to strengthen investigation of somatic mutations and gene expression profiles. …