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Clinical Pharmacist Assessment In Monitoring And Resolving The Adverse Drug Reaction In Bipolar Disorder Patients A Prospective, Observational Study At Tertiary Care Teaching Hospital, Parihar Ashish Singh, S. Ganachari Madiwalayya, V. Tekkalaki Bheemsain

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND:

Adverse drug reaction (ADR) is a noxious, unintended effect of the drug which may occur due to pharmacotherapy of the disease. Bipolar disorder is a chronic mental illness represented by mania, depression and cyclic episode. The treatment of Bipolar disorder is lifelong. Hence, there are increased chances of ADRs.

METHODOLOGY:

An observational, prospective study was performed on 286 patients, to identify, monitor, and resolve the ADR with bipolar disorder patients. The patients aged 18–65 years of either gender or diagnosed with bipolar disorder were enrolled in the study. Patient-related data had been collected from the patient record; probability of …

Correlates Of Suicide And Temporal Variations In Subjects With Suicide Attempt, Bandna Gupta, Prashant Choudhary, Adarsh Tripathi, Anil Nischal, Manu Agarwal

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND:

Suicide Attempt is a self-inflicted, potentially injurious behavior with a nonfatal outcome for which there was evidence of intent to die. Life changes could act as a stressor causing enhanced susceptibility for suicidal risk. Suicide is a complex public health problem due to interactive social, cultural, biological and psychological risk factors.

AIM:

To study suicide intent and it's association stressful life events in subjects with suicide attempt.

MATERIAL AND METHODS:

The study was cross-sectional, non-interventional study which included 102 patients. Semi-structured Performa including socio-demographic and clinical history details, Presumptive Stressful Life Events Scale (PSLES) [Singh

et al

., 1984] …

Evaluation Of Effect Of An Open Clinical Trial, Shubham Brajesh Gupta, Pradeep S. Shindhe, R. R. Hiremath

Indian Journal of Health Sciences and Biomedical Research KLEU

INTRODUCTION:

Constipation (

vibandha

) is a common clinical problem and symptoms of many diseases. It is not described as a separate disease in the classical text. Westerned life style, mental stress and diets are play major role in occurring in constipation (

vibnadha

). The diagnostic and evaluation of

vibandha

includes an proper history and investigation to exclude any other abnormalities and disease.

OBJECTIVE:

The objective of this study was to evaluate the effect of

kalyanaka kshara

in

vibandha

.

MATERIALS AND METHODS:

A clinical trial was conducted on a group of 30 patients diagnosed with the help of …

Excessive Gestational Weight Retention And Weight Gain In Postpartum Perception Of Women, Thilagavathy Ganapathy

Indian Journal of Health Sciences and Biomedical Research KLEU

CONTEXT:

Childbearing women are the second victims for significant gestational weight retention and weight gain during reproductive years. There may be unique reasons to weight management in this period.

AIM:

To explore what women perceive as reasons for their excessive gestational weight retention and weight gain in the postpartum period.

METHODS:

By purposive sampling,

n

= 200 low-risk postnatal women less than a year of postpartum were recruited and their perceived reasons for excessive gestational weight retention and weight gain in the postpartum period were assessed.

RESULTS:

Participants perceived lowered physical activity, sedentary lifestyle behavior, lack of knowledge, misconceptions that …

An Empirical Understanding On The Concept Of, Govardhan Belaguli, H. P. Savitha

Indian Journal of Health Sciences and Biomedical Research KLEU

Sattvavajaya Chikitsa

(SC) (

Ayurveda

Psychotherapy) is one among the brainchild concepts of

Acharya Charaka

(father of Indian medicine). In

Ayurveda

, SC is considered to be having the psychospiritual approach with a nonpharmacological treatment modality which solely deals on the mind and its related attributes. SC has 5 methodology, 2 principles, 3 dimensions, 3 psychotherapeutic domains, and 5 techniques. This psychotherapy helps in controlling

Manas

(mind) away from

Ahita Artha

(distractible, unwholesome objects/thoughts/perceptions). Withdrawal of the bothered mind from unwholesome objects is the prime focus of SC. Mainly focusing on the intelligence, consciousness, memory, and spiritual aspects of the …

Assessment Of Implementation Of The National Programme For The Prevention And Control Of Cancer, Diabetes, Cardiovascular Diseases, And Stroke At Subcenters Of Belagavi Taluka A Cross-Sectional Study, Vinayak H. Kashyap, M. S. Shivaswamy

Indian Journal of Health Sciences and Biomedical Research KLEU

CONTEXT:

Mortality due to noncommunicable diseases (NCDs) has increased worldwide and, according to the World Health Organization report in 2012, 68% of mortality was due to NCDs. In India, deaths due to NCDs in 2008 were 5.3 million. A rapid health transition is being experienced in India with a rising burden of NCDs. The first point of contact of patients with health services is primary health-care (PHC) facilities, which are the most appropriate places for patient screening and early detection. The National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular diseases and Stroke (NPCDCS) was launched in 2010 in …

Predatory Journals A Threat To Evidence-Based Science, Mamta Choudhary, Nancy Kurien

Indian Journal of Health Sciences and Biomedical Research KLEU

One of the latest threats emerged to the integrity of academic publishing is predatory journals. These journals have paved the way for low-quality articles by exploiting gold open-access publishing, threatening standards of evidence-based science. These journals lack the authentication of legitimate scholarly journals such as peer review, editing, editorial boards, editorial offices, and other editorial standards, imposing a number of new ethical issues in publishing research papers. Some of these claim to assess submissions within 72 h and digitally publish them on acceptance and receipt of the fee, showing their only motivation of procurement of evaluation and publication fees. While …

Do Noise Stress Impact To Addiction?, Sundareswaran Lognathan, Arbind Kumar Choudhary, Kuppusamy Mahesh Kumar

Indian Journal of Health Sciences and Biomedical Research KLEU

Numerous studies have illustrated the impact of stress on addiction, its development, relapse vulnerability, and the dopamine mechanism. However, various studies on noise exposures as a stressor had been done, which could alter the hypothalamic–pituitary–adrenal (HPA) axis. Noise exposure harmful effect and changes in the individual's health was at least consideration and were less noticed. This review elucidates the facts and consequences of noise exposure toward mesolimbic dopamine circuitry perceptible in addiction. Further, this review generates greater attention and awareness among people toward noise exposure influence on addiction and its relation with dopamine. The noise stress may act as a …

Trauma Center Is The Need Of The Hour, R. B. Nerli, Shridhar C. Ghagane

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

A Cross-Sectional Study On Knowledge And Practices Regarding Birth Preparedness And Complication Readiness Among Pregnant Women Attending Antenatal Clinic At Kle's Dr. Prabhakar Kore Hospital And Medical Research Center, Belagavi, Iravva F. Padaguggari, M. S. Shivaswamy, Sanjeev B. Chougule

Indian Journal of Health Sciences and Biomedical Research KLEU

OBJECTIVE:

The objective is to assess the level of knowledge and practices regarding birth preparedness and complication readiness (BP and CR) among pregnant women.

MATERIALS AND METHODS:

The study was carried out in 2400-bedded tertiary care teaching hospital, Belagavi, over a period of 3 months from September to November 2017. A total of 384 pregnant women attending the antenatal clinic at the tertiary care teaching hospital were included in the study by purposive sampling. A descriptive approach was adopted, including collection of information from the pregnant women through a pretested and structured interview questionnaire and the data were analyzed using …

Awareness And Attitude Toward Household Poisons Among Medical And Nonmedical Students A Comparative Study, D. Priyanka, Gurudatta S. Pawar, Jayashree G. Pawar, Ashutosh Baliram Potdar

Indian Journal of Health Sciences and Biomedical Research KLEU

INTRODUCTION:

There are innumerable things we use in our household on day-to-day basis. Many things that we use at home from cleaning products to cosmetics are toxic when we are not careful about them.

OBJECTIVES:

The study is carried out to assess and to compare the awareness and attitude of medical and nonmedical students toward household poisons and to bring awareness among the students and general public about household poisons.

MATERIALS AND METHODS:

A questionnaire containing 40 questions were given to the study category of students (300 students, 150 medical and 150 nonmedical), tabulated, and analyzed using SPSS 17.

RESULTS: …

Human Immunodeficiency Virus-Associated Thrombocytopenia Profiling Hematological Changes In The Human Immunodeficiency Virus-Infected And Aids Patients, Unnati Pitale, Deivanayagi Muthusamy, Manish Verma, Pritish Chandra Pal, Humera Ayesha, Kalyan Murru, Mvr Ratnam, Abhishek Singh Nayyar

Indian Journal of Health Sciences and Biomedical Research KLEU

CONTEXT AND AIM:

AIDS is an acronym for acquired immunodeficiency syndrome caused by a retrovirus known as human immunodeficiency virus (HIV) which breaks down the body's immune system, leaving the patient vulnerable to a host of life-threatening opportunistic infections, neurological disorders, or unusual malignancies. According to estimates by the WHO and UNAIDS, 35 million people were living with HIV globally at the end of the year 2013. The first AIDS case in India was detected in the year 1986. Seldom studies have been conducted correlating CD4 cell counts and complete blood picture including platelet counts in HIV infected and AIDS …

A Study On Safe Driving Performance Using Biofeedback Therapy Among Drivers In Delhi, Neelima Chakrabarty, Kumar Sumit, Kamini Gupta

Indian Journal of Health Sciences and Biomedical Research KLEU

INTRODUCTION:

Biofeedback therapy is essential for releasing the stress, gain awareness, and to control over psychophysiological processes. The current study deals with the impact of biofeedback therapy on drivers by comparing the performances of drivers on “Decision Time” (DT) test before and after the use of biofeedback therapy.

METHODOLOGY:

For this study, as a special case 40 drivers from special protection group were selected for administering the decision time (DT) from “Vienna Test System” before and after applying biofeedback therapy with respiratory training.

RESULTS:

The results of this study reveal the beneficial effects of biofeedback in reducing negative effects, thereby …

Extrapyramidal Movement Disorder?/Tourette Syndrome-Plus?, Prasad Mamidi, Kshama Gupta

Indian Journal of Health Sciences and Biomedical Research KLEU

Uraga

/

Sarpa

/

Bhujaga grahonmada

(UG) is one among the 18 types of

bhootonmada. Bhootonmada

denotes a category of psychiatric/neuropsychiatric conditions assumed to be caused by affliction of evil spirits (

bhuta

/graha). Till date, no studies have been conducted on UG and it is unexplored. The present study is focused on the better understanding of UG and its clinical applicability. UG is characterized by features of

Krodhanam

(aggressiveness/impulsivity),

Nishwasantam

(hyperventilation/anxiety/phobia),

Bhramantam

(agitation/restlessness/hyperactivity),

Trasyantam

(startle response/hyperekplexia/anxiety/phobia),

Raktaaksha

(red eyes/Kayser–Fleischer rings),

Stabdha drishtim

(prolonged staring/abnormal eye movements),

Jihwa

lolayantam/

Srikkinyau lihaan

(facial tics),

Sarpavat

prasarati/

Adhomukha shaayinam

(athetosis/chorea/motor tics/opisthotonus),

Chalam …

Probiotic Use In The Management Of Hypertension A New Era Of Therapeutic Management, Swapnil Purushottam Borse, Devendra Pratap Singh, Dilawar Upadhyay, Vipin Sharma, Manish A. Nivsarkar

Indian Journal of Health Sciences and Biomedical Research KLEU

Hypertension (HTN) has become a common chronic medical condition which affects ≥20% of adult population worldwide. HTN is assumed to be a major contributing factor for increasing complication of metabolic syndrome by adding one or more comorbidities such as heart disease, stroke, chronic renal failure, myocardial infarction, blindness, and dementia. HTN is also considered as a lifestyle disorder, and there are mainly two types of HTN, namely primary and secondary. Primary HTN is about 90%–95% of all cases of HTN and it is defined as high blood pressure due to genetic factors and nonspecific lifestyle, while secondary HTN is due …

The Promotion Conundrum Is It Time For Reform In Indian Dental Schools?, Vasanti Lagali-Jirge, Kamal Shigli

Indian Journal of Health Sciences and Biomedical Research KLEU

Promotion is an academic reward system for university faculty. The word promotion these days comes with mixed feelings. With our rapidly escalating population and increase in the number of dental schools and availability of specialists, faculty positions are rapidly getting saturated. In the early days, career advancements and promotion were primarily based on time. According to the current promotion guidelines, career advancement depends on performance, namely, publications, research, participation in other administrative responsibilities, and clinical work. However, publications seem to have a greater impact on the decision to promote. The Dental Council of India has devised a point system to …

Global Research Trends Of Literature In Sugar-Sweetened Beverages 2000–2016, Waleed M. Sweileh, Ansam F. Sawalha, Samah W. Al-Jabi, Saed H. Zyoud, Adham S. Abutaha

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND:

Sugar-sweetened beverages (SSBs) are commonly used. The objective of this study was to analyze the quantity and quality of published literature on SSBs and present the results in a bibliometric format.

METHODOLOGY:

Scopus database was used to retrieve documents from 2000 to 2015. Annual growth of publications, collaborations, geographic distribution, visualization and mapping of collaboration, author analysis, and top-cited articles will be presented and discussed.

RESULTS:

The total number of worldwide publications on SSBs was 3345, published in 27 subject areas. More than half (58.30%) of the SSB publications were within the area of medicine. The number of publications …

Prevalence Of Sensorineural Hearing Loss Among Type-Ii Diabetes Mellitus Patients Attending Kles Dr. Prabhakar Kore Hospital And Mrc A Cross-Sectional Study, Aniruddh Tiwari, Ramesh S. Mudhol

Indian Journal of Health Sciences and Biomedical Research KLEU

INTRODUCTION:

Diabetes mellitus (DM) is an important healthcare concern in the modern world. This disease and its complications can affect virtually every system in the human body. A possible complication of DM is sensorineural hearing loss (SNHL).

AIM:

The current study aimed to evaluate the prevalence of SNHL among the patients of type-2 DM attending the hospital as well as to correlate the severity of hearing loss to the duration of diabetes and the glycosylated hemoglobin (HbA1c) levels. A total of 125 known cases of type-2 DM were included in the study.

METHODOLOGY:

For each patient, a detailed history was …

Anaerobic Bacteriological Profile Of Leukorrhea In Reproductive Age Group Women, G. S. Spurthi, Sharada C. Metgud, Metgud Shridevi

Indian Journal of Health Sciences and Biomedical Research KLEU

INTRODUCTION:

Leukorrhea is one of the most common complaints of women in their reproductive age group attending the OBG OPD and Bacterial Vaginosis (BV) is its most common cause.

AIM:

of the study was to isolate and identify the anaerobic bacteria causing leukorrhea.

MATERIALS AND METHODS:

This was a cross sectional study conducted in a medical college and tertiary care hospital, on 250 married women in their reproductive age group attending the OBG OPD with complaints of leukorrhea. High vaginal swabs were collected from these women and BV was diagnosed using Amsel's clinical composite criteria. Anaerobic bacteria were isolated from …

Effect Of School-Based Intervention Program For Children With Obesity A Randomized Control Trial, Deepa C. Metgud, Apeksha A. Hungund, Archana A. Kulkarni

Indian Journal of Health Sciences and Biomedical Research KLEU

INTRODUCTION:

Obesity in childhood is a major health issue that is seen in both developed and developing countries. Childhood obesity is associated with high risk of adulthood obesity and a series of health problems such as insulin resistance, hypertension, hyperlipidemia, type II diabetes mellitus, sleep apnea, and psychosocial problems. With the social development and changes in lifestyles, currently children and adolescents are lacking physical activity.

METHODOLOGY:

This study was a randomized control trial. One thousand one hundred and sixty-five students were screened aged 6–12 years. Among the screened children, 32 obese children were recruited in the study and randomly allocated …

The Downsides Of Industry-Funded Development Of New Therapeutics, Mir Shoeb Ulla Adil, Ruqiya Sultana

Indian Journal of Health Sciences and Biomedical Research KLEU

Clinical trials are a series of studies that help evaluate the safety and efficacy of a newly discovered drug. Although government funds around 80% of basic research to discover new drugs, it does not sponsor clinical trials at a competent level. Most of the trials are financially supported by pharmaceutical companies which arecertainly a worthwhile contribution to drug discovery, but it also influences the outcome of a clinical trial by ensuring acceptable government policies. Studies revealed that industries often practice selective reporting where unfavorable results are concealed, and positive outcomes are over-published, thereby misleading policies and future research. These downsides …

Bed Wetting, R. B. Nerli

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Necessity To Invest In Research And Development Activities To Combat The Threat Of Antimicrobial Resistance World Health Organization, Saurabh Rambiharilal Shrivastava, Prateek Saurabh Shrivastava, Jegadeesh Ramasamy

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

A Study To Evaluate Cardiovascular Responses By Using Treadmill And Ergometer Bicycle Exercise In Young Adults, Alok Kumar Yadav, Jayasheela G. Bagi

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND AND OBJECTIVE:

Exercise is inevitable to keep good health status, advised for health promotion, diagnosis of diseases, and rehabilitation. Different types of exercise are performed as exercise tolerance, but tolerance is not same for every individual. Thus, the objective of this study is to evaluate the cardiovascular responses for three different intensities of exercise using treadmill and bicycle ergometer at fixed heart rate (HR) value in young healthy adults.

METHODS:

After obtaining the ethical clearance from the Institutional Ethical Committee, a total of 130 participants were screened and 48 randomly selected male and female individuals with age group of …

Prevalence Of Menopausal Symptoms Among Postmenopausal Women Of Urban Belagavi, Karnataka, Nidhi Pathak, M. S. Shivaswamy

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND:

According to the World Health Organization (1981), natural menopause is defined as no menses for 12 consecutive months with no obvious intervening cause. During the menopause, women may experience vasomotor, psychosocial, physical, as well as sexual dysfunction. Studies on menopausal issues and health demand priority in Indian scenario due to the growing population of menopausal women as a result of their increased life expectancy.

OBJECTIVE:

To know the prevalence of menopausal symptoms in the postmenopausal women aged 40–60 years.

METHODOLOGY:

A community-based cross-sectional study was conducted between January 1, 2016, and December 31, 2016, using a predesigned, pretested, structured …

Knowledge And Practice Of Needlestick Injury Preventive Measures Among Nurses Of Sana'a City Hospitals In Yemen, Gawad M. A. Alwabr

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND:

A needlestick injury is an accidental skin-penetrating stab wound from a hollow-bore needle containing another person's blood or body fluid, leading to infection of diseases transmitted by blood such as hepatitis B virus, hepatitis C virus, and human immunodeficiency virus. The purpose of this study is to assess the level of knowledge and practice of needlesticks injury prevention measures and to estimate the incidence of exposure to needlestick injury among nurses working in the governmental hospitals in Sana'a city, Yemen.

MATERIALS AND METHODS:

A cross-sectional study among a random sample of nurses (

n

= 259) were conducted. A …

Vitamin B12 Insufficiency In Excess Folic Acid Downregulates Methylenetetrahydrofolate Reductase Gene And Increases Homocysteine, Tumor Necrosis Factor-Alpha, And Oxidative Stress In Hepatocytes, Tejas Shah, Kalpana Joshi, Sanjay Mishra

Indian Journal of Health Sciences and Biomedical Research KLEU

OBJECTIVE:

Folate and Vitamin B12 (B12) are crucial for normal growth, development, and cellular functions. The aim of this study was to determine the effect of required and excess folic acid (FA) concentration and imbalance of FA and B12 caused due to folate fortification on hepatocytes health and function

in vitro

.

MATERIALS AND METHODS:

Human hepatocellular carcinoma (HepG2) cells were cultured in FA and B12 deficient media for 15 days and further were supplemented with required FA: (6 μM) and excess FA: (60 μM) individually and in combination with B12: (500 nM). We assessed HepG2 proliferation, viability, tumor necrosis …

Review Of Selected Herbal Phytoconstituents For Potential Melanoma Treatment, Bhaskar Kallappa Kurangi, Sunil Satyappa Jalalpure

Indian Journal of Health Sciences and Biomedical Research KLEU

Malignant melanoma is the most aggressive form of skin cancer, with a high mortality rate. The current chemotherapies have a relatively low success rate due to the development of multidrug resistance and side effects. Hence, there is need of discovering new compounds that are safe and more effective against melanoma to improve the efficiency and to lower the treatment cost for cancer care. Melanoma chemoprevention with natural herbal phytoconstituents is an emerging strategy to prevent, cure, or treat melanoma. This review summarizes the latest research in melanoma chemoprevention and treatment using the herbal phytoconstituents. Relevant mechanisms involved in the pharmacological …

Female Factors Infertility Laparoscopic Evaluation At A Public Health Facility In Ilorin, Nigeria, Lukman Omotayo Omokanye, Sabi Ibrahim, Abdulwaheed Olajide Olatinwo, Kabir Abayomi Durowade, Sikiru Abayomi Biliaminu, Ganiyu Adekunle Salaudeen

Indian Journal of Health Sciences and Biomedical Research KLEU

Background:

Infertility is a problem of global proportions, the majority being the residents of developing countries. The contribution of female factor is assuming a tremendous proportion. Laparoscopy remains an indispensable tool in the evaluation of the fertility potential of these female partners.

Aims:

This study was aimed at determining the various causes of female factor infertility among female partners of infertile couple in a tertiary health facility.

Methods:

A cross-sectional observational study of ninety seven (97) eligible infertile women who underwent diagnostic laparoscopy between 1st January 2012 and 31st December 2015 were enrolled for the study. The data were analyzed …

Assessment Of Knowledge Regarding Hazards Of Tobacco Use Among Police Personnel In Belagavi City A Cross-Sectional Study, Sudheer Shivalingappa Mang, Appasaheb S. Wantamutte, Ashwini Narasannavar, Mubashir Angolkar

Indian Journal of Health Sciences and Biomedical Research KLEU

Introduction:

Tobacco is a serious threat to health and ranks second as a cause of death globally, and it also ranks fourth in its input to years of life lost. The worldwide tobacco related mortality rate reached up to 4 million per year in 1998 and is expected to become 10 million per year in 2030. This is more than the total deaths from tuberculosis, malaria, maternal, and major childhood conditions combined.

Objective:

The aim is to assess the level of knowledge regarding hazards of tobacco use among police personnel in Belagavi city.

Methodology:

This study design was a cross-sectional …