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Multinucleate Cell Angiohistiocytoma, Connor A. Sheehan, Jayci G. Rhein, Jordan Hyde, Jason B. Lee, Sylvia Hsu

Department of Dermatology and Cutaneous Biology Faculty Papers

No abstract provided.

Midweek Memo, Georgia Southern University

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A Scoping Review Of Aviation Loss Of Control Inflight Research, Brian J. Roggow

Journal of Aviation/Aerospace Education & Research

Loss of control – inflight (LOC-I) contributes to aircraft accidents at unacceptably high rates. Significant industry efforts and research have aimed to improve LOC-I prevention, detection, and recovery. This scoping review of literature systematically analyzed LOC-I literature between 2014 and 2024. The scoping review synthesized research findings and recommendations from 116 relevant articles. The research findings and recommendations were also categorized using the SHELL model to identify prevalent and understudied themes. Significant research has examined angle of attack indicators, integrated flight directors, automated LOC-I avoidance, detection, and recovery systems, as well as associated nonlinear aerodynamic modeling. Additionally, human performance shaping …

Spectrum, Volume 55, Issue 7, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: New Scholarship to Support Engineering Students -- The Look of Sustainability -- Springing into Registration -- Effect of Social Media on Mental Health -- Say Yes to the Dress: SHU Students at NYCBFW -- Bovardi Breaks Record as Playoffs Near

Applying Machine Learning Methods To Laser Acceleration Of Protons: Synthetic Data For Exploring The High Repetition Rate Regime, John J. Felice, Ronak Desai, Nathaniel Tamminga, Joseph R. Smith, Alona Kryshchenko, Christopher M. Orban, Michael L. Dexter, Anil K. Patnaik

Faculty Publications

Advances in ultra‐intense laser technology have increased repetition rates and average power for chirped‐pulse laser systems, which offer a promising solution for many applications including energetic proton sources. An important challenge is the need to optimize and control the proton source by varying some of the many degrees of freedom inherent to the laser‐plasma interactions. Machine learning can play an important role in this task, as our work examines. Building on our earlier work in Desai et al. 2024, we generate a large ∼1.5 million data point synthetic data set for proton acceleration using a physics‐informed analytic model that we …

Chromatin Profiling Identifies Putative Dual Roles For H3k27me3 In Regulating Cell Type-Specific Genes And Transposable Elements In Choanoflagellates, James M Gahan, Lily W Helfrich, Laura A Wetzel, Natarajan V Bhanu, Zuo-Fei Yuan, Benjamin A Garcia, Robert J Klose, Alex De Mendoza, David S Booth

2020-Current year OA Pubs

Chromatin-based mechanisms contribute to the exquisite regulation of gene expression during animal development. But how those mechanisms evolved remains elusive. Here we investigate chromatin regulatory features in the closest relatives of animals, choanoflagellates. In a model choanoflagellate Salpingoeca rosetta, we compare chromatin accessibility and histone modifications to gene expression. Accessible genomic regions in S. rosetta primarily correspond to gene promoters, and we find no evidence of distal gene regulatory elements that resemble enhancers deployed to regulate developmental genes in animals. Remarkably, the histone modification H3K27me3 decorates genes with cell type-specific expression, revealing a functional similarity in S. rosetta and animals. …

Reply To The ‘Comment On “Why There Is No Evidence That Pyridine Killed The English Crabs”’, Alex Ford, Mark Fitzsimons, Crispin Halsall

School of Geography, Earth and Environmental Sciences

We highlight that the commentary by Peters which uses a CREED/CRED risk assessment framework supports the previous government reports that rejected the pyridine hypothesis and considers the previous evidence as unreliable. This reaffirms our conclusions that pyridine didn't kill the Teesside crabs.

Esplanade 94 Llc V. Aiyash

All Decisions

In this licensee holdover proceeding concerning a rent-stabilized single-room occupancy (SRO) unit, the landlord sought possession, claiming the tenant was a mere licensee or squatter. The tenant, appearing pro se, established that he had continuously resided in the unit since September 2019, openly, with the landlord's employees' knowledge. He also proved he requested a lease in November 2019 and paid rent to the landlord's agent. The court found the tenant qualified as a permanent tenant under Rent Stabilization Code § 2520.6(j), which grants permanent tenancy status to SRO occupants who reside for at least six months or request a lease. …

How Social, Behavioral, And Policy Factors Impact Water Satisfaction And Management In Urban Areas, Rafi Haikal, Thoriqi Firdaus, Siti Hilya Nabila, Rizqi Shafira Chairunnisa

Journal of Environmental Science and Sustainable Development

The issue of water management in Indonesia’s specific urban contexts, specifically in Surabaya as an industrial hub and Bali as a tourist destination, is of paramount importance due to its impact on public health and environmental sustainability. This study analyses water management and conservation factors by comparing two distinct urban areas. The research design employs Partial Least Squares Structural Equation Modelling (PLS-SEM), which involves a specialised approach for analysing the complex relationships between variables. The results of the analysis indicate that community attitudes in Surabaya, facilitated by infrastructure and technology, significantly predicts intention to perform (β=0.334, p<0.001) and water management satisfaction (β=0.409, p<0.001). In contrast, collaboration with the government enhances environmental constraints (β=0.285, p<0.003) and water management satisfaction (β=0.140, p<0.044). In Bali, where water management is based on traditional practices, community attitudes do not significantly affect water management satisfaction (β=0.095, p>0.431). Still, perceived …

Does Cognitive Frame Affect Clinical Reasoning Among Medical Students? A Cross-Sectional Study, Xiao C. Zhang, Sara A. Belko, Andrew J Monick

Department of Emergency Medicine Faculty Papers

Background Diagnostic errors affect patient safety and lead to high costs. Cognitive bias is a key source of diagnostic error, and the framing effect poses a particular clinical challenge. The extent to which individual factors affect susceptibility to the framing bias is unclear, and the role of expertise in particular is contested across the literature. Objectives This study investigated the effects of framing bias on diagnostic reasoning among medical students. We hypothesised that the effects attributable to framing would be mediated by the number of years of medical education completed. Methods Participants were randomly assigned on an automated basis with …

Short Term Hemodynamic Effects Of Atrial Fibrillation In A Closed-Loop Human Cardiac-Baroreflex System, Oluwasanmi Adeodu, Michelle Gee, Babak Mahmoudi, Rajanikanth Vadigepalli, Mayuresh V. Kothare

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Atrial fibrillation (AF) remains the leading cardiac cause of stroke and AF-related death rate in the United States has been increasing for over twenty years. While the effect of standalone AF on heart rate is well established, there is a lack of clarity on its impact on other critical hemodynamic metrics. This is ostensibly due to interaction with other common comorbidities, especially hypertension. In addition, AF has a complex relationship with the state of the baroreflex. Evidence indicates that baroreflex sensitivity (BRS), the ability of the intrinsic cardiac control system to initiate parasympathetic response, is suppressed during AF. Therefore, a …

Bankruptcy Judging After Williamson, Vincent S.J. Buccola

Coase-Sandor Institute for Law & Economics Research Paper Series

This Essay asks how bankruptcy judges ought to orient their substantial, statutory discretion in business reorganization cases. The motivating observation is that bankruptcy law enacts a kind of forced integration of productive assets. To shed light on the contemporary problems that bankruptcy judges face, I thus look to two classic approaches to the economic theory of the firm—from Oliver Williamson and from Oliver Hart. I conclude that nonjudicial institutions have largely surmounted the problems to which their theories point, leaving a different, and probably narrower, set of issues to worry about. Bankruptcy judges who have a notion that their job …

Formalism In Jewish Law, Chaim Saiman

Faculty Publications

Scholars differ as to the degree to which Jewish law is formalistic. This chapter aims to make sense of the debate surrounding formalism in Jewish law by distinguishing between three types of legal formalism: classic formalism, modern formalism, and detail-following formalism. Viewed through the lens of modern formalism, Jewish law is likely less formalistic than commonly assumed as it is not primarily concerned with constraining decision makers. Nor is Jewish legal discourse typified by its unified conceptual schemas that proceed from abstract concepts to bottom-line decisions in the way that classical formalism proceeds. This chapter introduces an alternative framing termed …

Effects Of Hydrological Connectivity On Created Marsh Sustainability, Katie Swann

LSU Master's Theses

While efforts are being made to curb the high rate of coastal land loss in Louisiana, and even to restore ecosystem services and functions, it is generally accepted that restoration of these areas and functions is not a one-to-one value. It may take decadal time scales to reach efficient functional processing of nutrients and carbon storage rates, which may never reach true capacity comparable to similar naturally-organized systems. Although it is imperative to preserve these areas, restoration of ecosystem services and biogeochemical processes of coastal wetlands are preferable to future without action scenarios. Effectively directing the use of the limited …

Prevalence And Clinical Impact Of Pseudohypercalcemia In Paraproteinemia: A Case And Cohort Study, Usman Sunusi, Li Chen, Nianyi Li, Jason K Y Lee, Irmeen Siddiqui, Erin Goodhue, Rongrong Huang, Jieli Li

Faculty, Staff and Students Publications

Background: Hypercalcemia is a common and serious complication of malignancy, often contributing to morbidity and mortality. In patients with paraproteinemia, elevated total calcium with normal ionized calcium, termed pseudohypercalcemia, can complicate diagnosis and lead to inappropriate treatment. While this phenomenon has been described in case reports, its prevalence and clinical impact in routine practice remain poorly defined.

Methods: We report a case of pseudohypercalcemia in a patient with IgG κ multiple myeloma and conducted a retrospective review of de-identified data to assess the prevalence and biochemical associations of pseudohypercalcemia in paraproteinemia. Available data included serum protein electrophoresis (SPEP), …

Translational Framework Linking Perfluoroheptanoic Acid (Pfhpa) Exposure To Metabolic Dysfunction Associated Steatotic Liver Disease In Adolescents, Brittney O Baumert, Ana C Maretti-Mira, Douglas I Walker, Zhenjiang Li, Nikos Stratakis, Hongxu Wang, Yinqi Zhao, Fabian Christoph Fischer, Qiran Jia, Damaskini Valvi, Scott M Bartell, Jiawen Carmen Chen, Thomas Inge, Justin R Ryder, Todd Jenkins, Stephanie Sisley, Stavra Xanthakos, David E Kleiner, Rohit Kohli, Sarah Rock, Sandrah P Eckel, Michele A La Merrill, Max M Aung, Matthew P Salomon, Rob Mcconnell, Jesse Goodrich, David V Conti, Lucy Golden-Mason, Lida Chatzi

Faculty, Staff and Students Publications

Background: The rising prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), particularly among pediatric populations, requires identification of modifiable risk factors to control disease progression. Per- and polyfluoroalkyl substances (PFAS) have emerged as potential contributors to liver damage; however, their role in MASLD remains underexplored. This study aimed to develop a translational framework integrating human and in vitro data to elucidate the effect of PFAS on MASLD development.

Methods: We measured PFAS plasma levels in the Teen-LABS cohort (n = 136), comprising adolescents with obesity (mean age = 16.8 years) undergoing bariatric surgery. Plasma samples were also analyzed using proteomic …

Nasal Microbionts Differentially Colonize And Elicit Cytokines In Human Nasal Epithelial Organoids, Andrea I Boyd, Leah A Kafer, Isabel F Escapa, Amal Kambal, Hira Tariq, Susan G Hilsenbeck, Hoa Nguyen-Phuc, Anubama Rajan, Joshua M Lensmire, Kathryn A Patras, Pedro A Piedra, Sarah E Blutt, Katherine P Lemon

Faculty, Staff and Students Publications

Nasal colonization by Staphylococcus aureus or Streptococcus pneumoniae is associated with an increased risk of infection by these pathobionts, whereas nasal colonization by Dolosigranulum species is associated with health. Human nasal epithelial organoids (HNOs) differentiated at air-liquid interface (ALI) physiologically recapitulate human nasal respiratory epithelium with a robust mucociliary blanket. Due to their natural stem-like properties, HNO lines are a long-term experimental resource that offers genetic diversity based on the different donors. To develop HNOs as a new model system for bacterial nasal colonization, we reproducibly monocolonized HNOs differentiated at ALI with S. aureus, S. pneumoniae, or Dolosigranulum …

Brca2 Deficiency And Replication Stress Drive Apobec3-Mediated Genomic Instability, Kathy Situ, Abby M Green, Et Al.

2020-Current year OA Pubs

BRCA2 plays a critical role in stabilizing stalled replication forks, yet critical gaps remain in understanding how BRCA2 deficiency triggers fork collapse and drives genomic instability. Here, we identify cytidine deaminase APOBEC3B as a key driver of this process. Using a unique uracil-in-DNA probe, we show that BRCA2 loss promotes APOBEC3B-mediated uracil accumulation in single-stranded DNA (U-ssDNA) at stalled forks. These lesions when processed by UNG2 and APE1, trigger fork collapse and release ssDNA fragments into the cytoplasm, activating NF-κB signaling. This in turn upregulates APOBEC3B expression, establishing a self-reinforcing loop that amplifies cytidine deamination at stalled forks and exacerbates …

Enampt/Tlr4 Signaling Drives Pah Cellular Phenotypic Switching And Lung Vascular Remodeling, Mohamed Ahmed, Zhiyu Dai, Et Al.

2020-Current year OA Pubs

BACKGROUND: The attenuation of cellular phenotypic switchingdriving PAH vascular remodeling remains an unmet therapeutic need. As eNAMPT (nicotinamide phosphoribosyltransferase)/TLR4 signaling significantly contributes to PH pathobiology, an eNAMPT-neutralizing ALT-100 mAb was utilized to rescue monocrotaline (MCT) and hypoxia/Sugen (Hy/Su) preclinical PH rat models and to evaluate eNAMPT/TLR4 involvement in endothelial cell (EC), smooth muscle cell (SMC) and monocyte/macrophage phenotypic switching.

METHODS: MCT-PH or Hy/Su-PH rats received IgG or ALT-100 mAb (subQ, beginning week 4) with measurements of PH severity and lung tissue scRNAseq at day 42.

RESULTS: PH severity indices (hemodynamic, histologic, vascular remodeling) were significantly attenuated in MCT-PH and Hy/Su-PH …

Use Of Growing Degree Days To Model The Dynamics Of Aboveground Biomass And Nitrogen Accumulation Of Winter Cover Crops, M. Pessotto, Trenton Roberts, C. Dos Santos, K. A. Hoegenauer, M. Bertucci, W. J. Ross, M. Savin

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Cover cropping is an important management practice that can benefit the cash crop and the environment. Plant species, weather, and cover crop termination influence biomass production and N fixation potential. This study was conducted to determine optimal termination dates for production systems in Arkansas based on growing degree days (GDD) for eight different cover crop species: Austrian winter pea (AWP) (Pisum sativum), balansa clover (Trifolium michelianum), barley (Hordeum vulgare), black-seeded oats (Avena sativa), common vetch (Vicia sativa var. Cahaba), cereal rye (Secale cereale), crimson clover (Trifolium incarnatum), and hairy vetch (Vicia villosa). Field studies were conducted at three research stations …

Biofilm Formation Of A Strain Of Bovine Escherichia Coli And Analysis Of Its Influencing Factors, Xin Zhang, Yunjiao Chen, Weijuan Jia, Zhilin Liu, Zelin Jia, Jiayu Cui, Huisheng Xiong, Yuhang Zhang, Xueli Wang

The Thai Journal of Veterinary Medicine

This study investigated the biofilm (BF) formation of a bovine-derived Escherichia coli (E. coli) strain (designated DL1907) and analyzed the factors influencing its formation. The BF-forming capacity, optimal formation time and temperature, as well as the effects of different culture media, pH levels, NaCl concentrations, and glucose concentrations, were assessed using the crystal violet method. The results demonstrated that the strain had a strong BF-forming capacity, achieving the most intact BF structure after 36 h of culture at 37°C. Trypticase Soy Broth (TSB) medium promoted the strongest BF formation compared to Luria-Bertani (LB) and Müller-Hinton Broth (MH) media. …

Molecular Identification Of Cryptosporidium Spp. Isolated From Dairy Calves In The Northern Region Of Algeria, Dadda Anes, Abdellah Mohamed Cherif, Aoun Leila, Chatanun Eamudomkarn, Khelef Djamel, Keeseon S Eom, Dongmin Lee, Barakaeli Abdieli Ndosi, Mohammed Mebarek Bia

The Thai Journal of Veterinary Medicine

Cryptosporidium spp. is the most frequent agent in Algeria that causes neonatal diarrhea in calves, with high symptomatic diarrhea in pre-weaned dairy calves. The study aims to measure the prevalence, distribution, and genotype of Cryptosporidium-infected calves in one of Algeria's high milk production areas (North Central and Northeast). From 35 dairy cattle farms were selected 172 (77 with diarrheic and 95 without diarrheic symptoms) calves aged less than 60 days. Twenty-three farms (65.71%) were detected with cryptosporidiosis using a modified Ziehl-Neelsen stain, whereby 68 calves (39.53%) were obtained positive. The Copro-ELISA test gave an individual prevalence of (37.66%, 22.11%) …

Event Conclusion, Liberty University

Sport Leadership Summit

The Sport Leadership Summit (SLS) provided emerging sport professionals an opportunity to engage with industry leaders. Participants learned to identify best practices and applied relevant research while developing meaningful relationships with other sport professionals. Speakers came from a variety of organizations and addressed current industry topics. The SLS included panel discussions, keynote speakers, research presentations, and professional development sessions focused on equipping students for the next phases of their career development.

Examining The Evolution Of Coaches Issues In Interscholastic Sport, Tyler J. Ratts, Eric W. Forsyth, Zachary C. T. Evans, James E. Johnson, Michael Fraina, Warren A. Whisenant

Global Sport Business Journal

Central to interscholastic athletic programs are coaches who directly affect the developmental outcomes experienced by student-athletes through their participation (Blanton et al., 2024; Grant, 2024; O’Boyle, 2014). Forsyth et al. (2022) analyzed the key issues perceived by athletic administrators to affect the coaching position, with Coaches Education rated as the single most important issue and Finding Coaches and Retaining Coaches also deemed to be of very high importance. Over time, the coaching role has continued to evolve, as increased role demands (Ratts, 2025), changing stakeholder expectations (Johnson et al., 2019; Stoffer et al., 2021), and growing burnout and turnover (Martin …

Stay To Play: Multi-Level Stakeholders And Motivation In Youth Sports Tourism, Brumby Mcleod, Ph.D., John Grady, Ph.D.

Proceedings of the Recreation Experience Community Network Research Symposium

In this study, the stay to play model of hosting elite youth sports events was investigated by exploring the various stakeholder perspectives in staging youth sport events, specifically soccer. This research explored the motivations and gaps among the event organizers, the housing authorities (booking agencies), governing bodies and leagues, as well as the destination marketing organization. This study explored the relationship, unique value proposition, and gaps between the services provided by the stay to play organizers and participants. By exploring these concepts, a better understanding of the stay to play model is achieved, and destination marketers and management associations can …

Sun, Fun, And Structure: What Resort Activity Schedules Reveal, Phileshia Dombroski, Ph.D., Kayla D. Mohney, Ed.D., Rebecca L. Moriarty, Ava Beal, Libby Scanlon, Emily Bailey, Cyan N. Kvacky

Proceedings of the Recreation Experience Community Network Research Symposium

Daily activity schedules are central to the guest experience in resort environments, guiding participation, communicating brand identity, and structuring leisure time. This mixed-method content analysis explored how resorts across the United States design and present these schedules, emphasizing accessibility and program diversity. Eighteen publicly available resort activity schedules were evaluated using accessibility tools (PAC 3, Adobe Acrobat, WCAG 2.2) and coded for 4,166 individual activities across eight categories. Findings revealed moderate adherence to accessibility standards. Most schedules met minimum font size and color contrast guidelines, but only 25% were compatible with screen readers and 80% lacked alternative text or structural …

Perceived Value Of Sport And Recreation In Aruba: Resident Perceptions Of Health, Lifestyle, And Physical Activity, Stephen L. Shapiro, Andy Gillentine, Jo-Anne Croes, John Wardlaw

Proceedings of the Recreation Experience Community Network Research Symposium

Sport and recreation play an important role in shaping community well-being, particularly in small island nations where health and tourism are integrated. This study examines how Aruban residents perceive the value of sport and recreation and how these perceptions vary based on the type of activity and children’s participation in these activities. A mixed-methods design was used across two phases. Phase I employed focus groups with residents, educators, and government stakeholders to explore themes of health, community impact, and education. Findings emphasized concerns over inactivity and identified sport and recreation as essential to promoting healthy lifestyles, sense of community, and …

Drivers Of Policy Support And Political Consumerism Behavior Among Water Recreationists, Mina Kim

Proceedings of the Recreation Experience Community Network Research Symposium

Individuals who engage in water-based recreation share a distinct bond with water quality due to their direct contact with aquatic environments during leisure activities. Increasing concerns about water quality have led to a rise in research exploring how environmental conditions and perceived risks shape environmental attitudes and conservation actions. However, it remains uncertain whether water recreationists extend their conservation efforts beyond those directly tied to their activities. To explore this issue, the present study investigates whether water-based recreationists in South Carolina support more stringent water management policies and engage in political consumerism behaviors, such as boycotting and buycotting. Data were …

Alice Keane, J.D., Ll.M., Alice E. Keane

Faculty Research Mixer

No abstract provided.

How Did The Pandemic Change The Role Of Recreational Waters In Bringing Visitors? Analysis Of South Carolina Mobility Big Data, Seonjin Lee, Lori Pennington-Gray, Ph.D.

Proceedings of the Recreation Experience Community Network Research Symposium

The COVID-19 pandemic had a profound impact on nature-based recreational activities. Outdoor recreation became popular as an alternative to international travel with less risk of contagion. However, the question remains whether there was an enduring change in the role of natural resources in driving visitors. This study investigates the relevance of recreational waters, particularly lakes and beaches, to changes in patterns of domestic visitors to South Carolina between 2019 and 2023. All counties showed growth in recreational visitors, as well as diversification of visitors. However, the magnitude of the increase showed a significant difference based on geographical factors. Eight coastal …