Digital Commons Network^™

Reply To Fernández Et Al. Comment On "Goudra Et Al. Anesthesia For Bronchoscopy-An Update, Basavana Goudra, Lalitha Sundararaman, Prarthna Chandar, Michael Green

Department of Medicine Faculty Papers

No abstract provided.

Complement Activation In Secondary Thrombotic Microangiopathies, Johann Morelle, Fernando Caravaca-Fontan, Fadi Fakhouri, Eleni Frangou, Annette Bruchfeld, Jürgen Floege, Safak Mirioglu, Sarah M Moran, Stefanie Steiger, Kate I Stevens, Onno Y K Teng, Selda Aydin, Anuja Java, Sjoerd A M E G Timmermans, Andreas Kronbichler

2020-Current year OA Pubs

Secondary thrombotic microangiopathies (TMAs) represent a heterogeneous group of diseases associated with a high risk of kidney failure and death despite available therapeutic strategies. Strong evidence implicates complement activation in the pathogenesis of secondary TMA, and emerging data increasingly suggest that pharmacological blockade of the complement improves the outcomes in patients with secondary TMA. Certain forms of secondary TMA, including postpartum TMA, TMA with coexisting hypertensive emergency and de novo TMA after kidney transplantation exhibit a high prevalence of pathogenic variants in complement genes, similar to those observed in primary atypical haemolytic uraemic syndrome. These conditions should be considered as …

Cohesin Haploinsufficiency Is Tolerated In Cbfb::Myh11-Driven Murine Acute Myeloid Leukemia, Shannon E Conneely, Alexis Quezada, Kristen J Kurtz, Nenggang Zhang, Josephine De La Fuente, Nesa Mercer, Jason H Rogers, Rogelio Aguilar, Geraldo Medrano, Margaret A Goodell, Paul P Liu, Debananda Pati, Rachel E Rau

Faculty, Staff and Students Publications

Cohesin gene mutations occur in many malignancies, including acute myeloid leukemia (AML). Loss-of-function mutations in the four major cohesin complex genes (RAD21, SMC3, SMC1a, and STAG2) occur across most major genetic subtypes of AML but are notably absent in AML harboring CBFB::MYH11, suggesting that cohesin mutations yield distinct biological outcomes dependent on the genetic AML driver. We hypothesized that CBFB::MYH11-expressing leukemias would be dependent on intact cohesin genes given their near-mutual exclusivity. To investigate this, we combined either germline or inducible heterozygous deletions in cohesin genes Smc3 or Rad21, respectively, with an inducible murine model of Cbfb::MYH11 AML. This approach …

Obesity Vs. Overweight Status: Differential Predictions To Poly-Substance Use In Young Adulthood, H. Isabella Lanza, Kailey Waller, Lalaine Sevillano

School of Social Work Faculty Publications and Presentations

Background:

Though past research has identified links between higher weight status and substance use in young adulthood, prospective studies are scarce and mixed, the role of higher weight status on vaping is less clear, and little empirical work has examined differences between obesity vs. overweight on poly-substance use. The current study assessed the role of weight status on poly-substance use trajectories across young adulthood.Methods1,303 young adults (20.5 ± 2.3 years; 63% female; 41% Latina/o/x, 30% Asian-American/Asian, 18% Caucasian/White) from a public, urban university were surveyed at six-month intervals from spring 2021 (W1) to spring 2023 (W5). Weight status was measured …

Distinct Molecular Responses Of Human Intestinal Organoids To Proton And Photon Radiation, Victoria Poplaski, Tajhal D Patel, Hoa Nguyen-Phuc, Amal Kambal, Lawrence Bronk, Mary K Estes, Cristian Coarfa, Sarah E Blutt

Faculty, Staff and Students Publications

Radiation exposure impairs rapidly renewing tissues like the intestinal epithelium, yet translational insights from murine models have been limited by species-specific responses. Here, we use human intestinal organoids (HIOs) derived from jejunal epithelium to evaluate human epithelial responses to low dose proton and photon (gamma) radiation. Gamma irradiation induces a unique developmental and metabolic shift in crypt-like organoids, including enrichment of amino acid metabolism pathways and activation of fetal-associated transcription factors and morphology. Integrated multi-omic profiling reveals serotonin biosynthesis as a central regenerative node. Human intestinal organoids can complement animal models and are emerging as a powerful tool in modeling …

Takaful Insurance In The Palestinian Territories: Reality And Development Mechanisms, Ismaeil Mohammad Shindi Amayreh, Kifah Abdul Qader Al Ssuwari

Journal of King Abdulaziz University: Islamic Economics

This study aims to investigate Takaful insurance in the Palestinian territories, as one of the most important financial cases that has gained prominence on the Palestinian economic landscape following the establishment of Islamic banking. This study provides a comprehensive analysis of the current state of Takaful insurance, identifying obstacles and challenges that hinder its growth in Palestine. Given the distinct socio-economic and political circumstances in Palestine, and in an attempt to create practical mechanisms for the development of Takaful insurance in this region, the study aims to promote the role of Takaful insurance in fostering public confidence. Takaful offers insurance …

The Tax Adviser, Volume 7, Number 11, November 1976, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Author Index, 12 Months Ended October 1976, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Subject Index, 12 Months Ended October 1976, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Tax Trends, E. S. Linett

Tax Adviser

No abstract provided.

Washington Report: The Illegal Payment Questionnaire Revisited, Thomas R. Hanley, George G. Bauernfeind

Tax Adviser

No abstract provided.

Spotlight, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Tax Litigation Reform, John J. Sexton, James P. Parker

Tax Adviser

No abstract provided.

Exploring Health Care Professionals’ Perceptions Of Live Actor Avatar And Ai Avatar Simulated Patient Interactions, Leslie Rippon, Lorene Cobb, Marcia Downer, Alicia Mcgregor, Natalie Neubauer, Lauren Snowdon, Genevieve Zipp

Journal of Innovation in Health Sciences Education

Introduction: The increasing use of simulation in health care and advancing capabilities of virtual technology have increased the use of virtual avatars. Recently, the development of large language models has created an opportunity for virtual reality (VR) simulation through combination of VR and artificial intelligence (AI). This study sought to evaluate the perception of authenticity in prerecorded virtual simulated patient interactions using two different avatar platforms: AI avatar and live actor avatar.

Methods: Participants included 41 health professionals with patient care experience, of which 32 completed the post experience survey. Using a repeated measures mixed methods research design allowed …

Perceptions Of Respect Among Dental Hygiene Students: A Qualitative Study, Jennifer Fehrenbacher

Journal of Innovation in Health Sciences Education

Introduction: Respect for others is an attribute that honors the dignity of individuals. As such, it is a key component in the creation of a positive teacher–student environment that leads to academic success. Because of the subjective nature of the term respect, it is important to determine how specific students perceive it. The purpose of this qualitative study was to explore dental hygiene student perceptions of respect and inquire into their related academic success and care of their own patients. The insights gained from this study could be used to help guide teacher awareness of the needs of students …

The Tax Adviser, Volume 7, Number 12, December 1976, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Author Index, 12 Months Ended November 1976, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Tax Trends, E. S. Linett

Tax Adviser

No abstract provided.

Washington Report: Regulation Of Income Tax Return Preparers Under The Tax Reform Act Of 1976, Thomas R. Hanley, William Stromsem

Tax Adviser

No abstract provided.

Spotlight, Roger Miller

Tax Adviser

No abstract provided.

Beware The Esop: A Cautionary Tale, Herbert A. Huene

Tax Adviser

No abstract provided.

Jeopardy And Termination Assessments The Laing Case And The Tax Reform Act Of 1976, Philip J. Harmelink, Nancy E. Shurtz

Tax Adviser

No abstract provided.

Rou Dalagurr Native Council Youth Voices Leading Curriculum Change, Cutcha Risling Baldy

Rou Dalagurr Food Futures

Building a Health Curriculum Lesson for Grades 9-12 in the Native American Studies Model Curriculum for California

Growing Relations With Remagination Farm, Paul Michael L. Atienza

Rou Dalagurr Food Futures

An electronic message exchange between Dr. Robyn Rodriguez, co-founder of the Remagination Farm, and Dr. Paul Michael L. Atienza, assistant professor of Critical Race, Gender & Sexuality Studies at Cal Poly Humboldt.

Place-Based Learning Practices: Institutional Responsibilities, Karley Rojas

Rou Dalagurr Food Futures

The 'Place-Based Learning Practices Project' (PBLP) is a graduate project under the Native American Studies Department Rau Dalagurr Food Sovereignty Lab and Traditional Ecological Knowledges Institute (FSL). Making contributions at the intersection of Western academia and Indigenous science, it imagines and realizes content, policies, and protocols surrounding two case studies and the larger cal poly humboldt (cph) institution which respect, honor, and uplift Indigenous sovereignty and resurgence in partnership with the Blue Lake Rancheria Tribe and the greater regional tribal community. Encompassing two projects internal and external to the institution, I aim to address the construction of controlled and protective …

''Thanks For The [Land] Acknowledgement, Now What?'': Settler Histories And Decolonial Futures At Cal Poly Humboldt's Schatz Tree Farm, Sangeeta Sarkar

Rou Dalagurr Food Futures

As California's newest polytechnic university, Cal Poly Humboldt is often lauded for its Indigenous-­facing programming and commitments to Indigenous peoples. In recent years, Native American Studies faculty, staff, and students, alongside Indigenous community partners, have led conversations about Cal Poly Humboldt meaningfully supporting tribal sovereignty by returning land to Native nations. As Cutcha Risling Baldy summarized in a research interview, "Thanks for the [land] acknowledgement, now what?" (2024, personal interview). However, though Cal Poly Humboldt has made various land acknowledgements and references to Indigenous peoples in its university policies, conversations about #LandBack have been met with resistance from the university. …

Full Issue

Rou Dalagurr Food Futures

No abstract provided.

Seroprevalence Of Small Ruminant Lentiviruses (Srlvs) And Peste Des Petits Ruminants Virus (Pprv) In Nonvaccinated Sheep And Goats In Sarawak, Malaysia, Bura Thlama Paul, Ali Saidu, Maria Eva Barudi, Faez Firdaus Abdullah Jesse, Juriah Kamaludeen, Suhaili Mustafa, Masnindah Malahubban, Ali Hanafiah Hakim, Krishnan Nair Balakrishnan, Mohd Azmi Mohd Lila

The Thai Journal of Veterinary Medicine

Small ruminant lentiviruses (SRLVs) and Peste des Petits Ruminants virus (PPRV) are economically important viral diseases that threaten small ruminant production globally. While previous studies have reported their serological status in Peninsular Malaysia, there is limited epidemiological information on their occurrence in East Malaysia. This study aimed to determine the seroprevalence and risk factors of SRLVs and PPRV among nonvaccinated sheep and goats from selected smallholder farms in Sarawak. A total of 245 serum samples collected from sheep (n = 117) and goat (n = 128) were screened using commercial ID Screen^® PPR competition (PPRC ver. 0821) and MVV/CAEV …

Scaling Down Safe: Can The Scaled Agile Framework Be Adopted By Small And Medium Enterprises? A Multiple Case Study, Ritchie Piessens, Pascal Ravesteyn, Benny De Waal

Communications of the IIMA

The Scaled Agile Framework (SAFe) has gained significant traction in recent years as a strategy to mitigate the risks associated with traditional front-end planning, which often results in downstream development challenges. The adoption of SAFe is not common for Small- and Medium Enterprises (SMEs), as its implementation is often perceived as complex, time-consuming and resource-intensive. However, the application of SAFe can add value for SMEs as well, when adapted and scaled down for use in those organisations. This qualitative multiple case study was undertaken to deepen our understanding of the applicability of the seven core competencies of SAFe in business …

The Criminal Liability Provisions Of Artificial Intelligence (Ai) Actions, Fatmah Ali Al Dhanhani

Thesis/ Dissertation Defenses

This study aims to define the concept and levels of artificial intelligence (AI) to understand its legal nature, personality, and impact on criminal liability. It analyzes the current legal frameworks and examines existing legislation related to AI, assessing their ability to address issues concerning criminal responsibility for the actions of these systems. The study begins by defining the precise concept of criminal liability to understand how it can be applied in a technological environment. It then defines AI and explores its legal nature, to analyze current frameworks and evaluating how effectively they deal with questions of criminal accountability for AI’s …