Digital Commons Network^™

Identifying Opportunities For Learning Following A Serious Incident, Laura Herring

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Demonstrating How Consistent Kindness, Presence, And Patient Advocacy Improve Engagement And Dignity In Secure Forensic Mental Health Settings, Patricia Quarshie

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Bridging The Gap: Enhancing Healthcare Support Worker Confidence And Skills Through A Nursing Associate Led Study Day, Lindsay Ewing

South West Clinical School Journal

#400WORDS: NATIONAL NURSING ASSOCIATE SPECIAL EDITION

Fgf13 Regulates Vgsc-Independent Cardiomyocyte Impulse Propagation Via Cx43 Trafficking, Lala Tanmoy Das, Mattia Malvezzi, Aravind R Gade, Maiko Matsui, Margaret Mckay, Eric Q Wei, Matea J Zelich, Keon Mazdisnian, Jared Kushner, Bi-Xing Chen, Isabella Distefano, Daniel Roybal, Lin Yang, Lisa Stoll, James C Lo, Marian Kalocsay, Fadi G Akar, Steven O Marx, Geoffrey S Pitt

Faculty, Staff and Student Publications

Background: FHF (fibroblast growth factor homologous factor) variants associate with arrhythmias. Although FHFs are best characterized as regulators of voltage-gated sodium channel (VGSC) gating, recent studies suggest broader, non-VGSC-related functions, including regulation of Cx43 (connexin 43) gap junctions and hemichannels, mechanisms that have generally been understudied or disregarded.

Methods: We assessed cardiac conduction and cardiomyocyte action potentials in mice with constitutive cardiac-specific Fgf13 ablation (cFgf13KO) while targeting Cx43 gap junctions and hemichannels pharmacologically. We characterized FGF13 regulation of Cx43 abundance and subcellular distribution. With proximity labeling proteomics, we investigated novel candidate mechanisms underlying FGF13 regulation of Cx43. …

“Chords Of Inquiry”: Alternate Guitar Tunings, Harmony, And Text-Music Relations In Joni Mitchell’S Early Songs, Peter Kaminsky, Megan Lyons

Open Access Fund Publications

In the 2003 documentary Woman of Heart and Mind, Joni Mitchell states, “Chords are depictions of emotions. These chords that I was getting by twisting the knobs on the guitar until I could get these chords that I heard inside that suited me, they feel like my feelings. You know, I called them, not knowing, chords of inquiry.” In investigating Mitchell’s music, we address the integration of guitar, harmony, and expression of feeling exemplified by “chords of inquiry.” We take as a corpus her early songs from 1968 to 1972 in which she accompanies herself on guitar. Our study …

Periodontal Precision: Diagnostic Skills And Confidence Of Dentists In Asian Countries In Applying The 2017 Efp/Aap Periodontal Disease Classification- A Cross-Sectional Pilot Study, Kamran Ali, Priti Charde, Daniel Zahra, Ewen Mccoll, Tayeb Al Hadeethi, Nader Hamdan

Peninsula Dental School

Background: The classification of periodontal disease published in 2017 by the European Federation of Periodontology (EFP) and American Academy of Periodontology (AAP), provides a framework for diagnosis and treatment. The aim of this study was to evaluate the diagnostic skills and self-perceived confidence of dentists and dental students based in Asian countries in the use of this classification. Methods: A cross-sectional analytic study design was employed. An online questionnaire encompassing four periodontitis cases was used for data collection. A total of 500 participants were invited to provide a diagnosis and rate their confidence for each case. Results: Responses were provided …

Iconic Voices And Ai: The Legal Battle Against Voice Cloning, Ezra Ashkenazi

Cardozo Arts & Entertainment Law Journal (AELJ) Blog

In a recent interview with The Guardian, the legendary Hollywood actor, Morgan Freeman, expressed his distaste with AI’s use of his voice. Freeman went on to say, “I get paid for doing stuff like that, so if you’re gonna do it without me, you’re robbing me.” Freeman went further and said that his lawyers “[A]re already ‘very, very busy’ tackling unauthorized artificial intelligence uses of his voice.” While that is the last we have heard from Freeman and his legal team on the matter, this article will analyze the potential legal arguments one can bring to enjoin a company’s …

The Impact Of Artificial Intelligence On Employee Attrition And Organizational Profitability, Saeed Almehairi

Theses

Artificial Intelligence (AI) has become a transformative force in the modern workplace, reshap- ing decision-making processes, enhancing operational efficiency, and influencing the dynamics of human resource management. One of the critical areas where AI demonstrates substantial potential is in predicting, managing, and mitigating employee attrition. Employee attrition remains a pressing organizational challenge, incurring substantial costs in recruitment, training, and lost productivity. This research investigates the dual impact of AI on employee attrition and organizational profitability, exploring both the opportunities and the challenges that arise from its integration into human resource and business operations. The study examines how AI-driven predictive analytics …

Harnessing Ai For Assessing Government Digital Maturity, Mohammed Zhair Swalha

Theses

This paper provides a comprehensive analytical examination of the Global Technological Maturity Index (GTMI), with a focus on assessing the determinants of national digital maturity and structurally modeling GTMI performance. Using rigorous data preparation methods including imputation, feature transformation, and exploratory statistical analysis the study applies multiple regression models (Decision Tree, Random Forest, Gradient Boosting, and MLP) to replicate the GTMI structure and identify its primary drivers. The UAE demonstrates a strong maturity profile, ranking in the  Very High  category globally. Deviation analysis shows that the UAE aligns closely with global leaders across the most structurally divergent indicators. Among the …

Increased Intermembrane Space [Ca2+] Drives Mitochondrial Structural Damage In Cpvt, Shanna Hamilton, Radmila Terentyeva, Roland Veress, Fruzsina Perger, Zuzana Nichtova, Mark Bannister, Jinxi Wang, Sage Quiggle, Rachel Battershell, Matthew Gorr, Sandor Györke, Bum-Rak Choi, Christopher George, Andriy Belevych, György Csordás, Dmitry Terentyev

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Mitochondrial dysfunction caused by abnormally high RyR2 (ryanodine receptor) activity is a common finding in cardiovascular diseases. Mechanisms linking RyR2 gain of function with mitochondrial remodeling remain elusive. We hypothesized that RyR2 hyperactivity in cardiac disease increases [Ca 2+ ] in the mitochondrial intermembrane space (IMS) and activates the Ca 2+ -sensitive protease calpain, driving remodeling of mitochondrial cristae architecture through cleavage of structural protein OPA1 (optic atrophy protein 1).

METHODS: We generated a highly arrhythmogenic rat model of catecholaminergic polymorphic ventricular tachycardia, induced by RyR2 gain-of-function mutation S2236L(Ser2336Leu)(+/-) . We created a new biosensor to measure IMS-[Ca2+ ] …

Functional Vs Anatomical Cortico-Striatal Connectivity In The Macaque Brain, Wei Tang, Megan E Monko, Zoe Liu, Ana M G Manea, Fernando A Ortega, Damyan Hart, Jason Zhou, Jan Zimmermann, Sarah R Heilbronner

Faculty, Staff and Students Publications

The cerebral cortex provides the main input to the striatum, constituting the first step in cortico-basal ganglia loops. Decades of careful anatomical tract-tracing research have established the exquisite topography of each cortical region's projection to the striatum in nonhuman primates. In parallel, neuroimaging research has demonstrated the relationship between cortico-striatal resting-state functional connectivity and specific cognitive, behavioral, psychiatric, and neurological states in humans. However, still unclear is the extent to which functional connectivity recapitulates the specific topographies of cortico-striatal anatomical connectivity. Here, we combined datasets of cortico-striatal anatomical and functional connectivity in macaques to determine the degree of overlap between …

An Innovative Hdm Model For Assessing Renewable Heat Energy Resources In Utility Energy Systems, Mark Alan Ryan

Dissertations and Theses

Renewable Heat Energy projects exhibit numerous unique, complex, and often conflicting characteristics, including varying project sizes, diverse energy resources, stakeholder demands, and significant challenges in energy conversion applications. Traditionally, cash flow analysis and return on investment are the most widely recognized metrics for evaluating remote energy projects. However, numerous quantitative and qualitative factors influence the overall performance and success of Renewable Heat Energy System (RHES) projects. A comprehensive approach using advanced tools is essential for assessing the factors and criteria that significantly impact these projects.

This research investigates the key quantitative and qualitative factors that contribute to the successful implementation …

Signal Processing Of Ecologically Significant Signals For Transient Bedload Characterization, Nathan R. Sjullie, Quinn B. Morgan, David Burnett

PSU McNair Scholars Online Journal

When rivers achieve a great enough flow rate, sediment along their riverbed becomes mobilized and transported downstream. This process is known as bedload transport. As bedload transport initiates, micro-collisions of various sediments and gravel generate underwater acoustic signals that can be detected by hydrophones. While there is extensive research on underwater acoustic theory and surrogate methods for monitoring bedload transport, there is a lack of heuristic work that analyzes collected bedload samples in conjunction with underwater acoustic recordings. The aim of this work is to complete an analysis on collected bedload samples and the simultaneous underwater acoustic recordings via signal …

A Mouse Model Of Lipoatrophy Reveals Relationships Between Beige Fat Appearance And Female Fertility, Elizabeth S Anaya, William Dion, Pradip K Saha, Aaron R Cox, Evelyn De Groot, Avery A Ahmed, Jessica B Felix, Bokai Zhu, Stephanie A Pangas, Sean M Hartig

Faculty, Staff and Students Publications

White adipose tissue (WAT) performs vital metabolic and endocrine functions, but roles in female reproduction remain understudied and poorly understood. Here, we report that female mice experiencing progressive lipoatrophy after knockout of Ubc9 in adipocytes (Ubc9fKO) displayed disrupted estrous cycles, reduced ovarian reserve, and subfertility. During aging, female Ubc9fKO mice lose subcutaneous WAT more quickly than their male counterparts and weigh less than littermate controls. Subcutaneous WAT excised from female Ubc9fKO mice strongly enriched for thermogenesis genes generally associated with metabolic benefits. Female Ubc9fKO mice exhibited hypermetabolism and accumulated thermogenic, Uncoupling Protein 1-expressing beige fat cells in residual subcutaneous WAT …

Synergistic Potential Of Sipuleucel-T In Enhancing Immunotherapy For Metastatic Castration-Resistant Prostate Cancer, Kavita Rawat, Varnika Punia, Parker Mathews, Sara Mccoy, Wilbur Song, Muhammad A Saeed, Russell K Pachynski

2020-Current year OA Pubs

Clinical trials of immunotherapy in metastatic castration-resistant prostate cancer (mCRPC) have largely been unsuccessful despite promising preclinical studies and proven efficacy in other solid tumors. These disappointing clinical outcomes have been attributed to an immunosuppressive tumor microenvironment, a relative lack of infiltrating immune effector cells, and tumor-related and host-related factors, which collectively render prostate cancer a relatively immunologically "cold" tumor. Sipuleucel-T (Provenge), an autologous cellular immunotherapy, induces an immune response targeted against prostatic acid phosphatase. It received approval from the US Food and Drug Administration in 2010, marking the first immunotherapy to show an overall survival benefit in patients with …

Patient-Centered Televisit For Chronic Obstructive Pulmonary Disease Discharge Transitions: User-Centered Design Study, Joanna Abraham, Alicia Meng, Nicolas Caravelli, Leah Traeger, May Nguyen, Vineet Arora, Valerie G Press

2020-Current year OA Pubs

BACKGROUND: Chronic obstructive pulmonary disease (COPD) affects approximately 16 million Americans and often results in avoidable readmissions due, in part, to medication errors and lack of education. Telehealth interventions can support medication reconciliation and inhaler education following hospital discharge for patients with COPD.

OBJECTIVE: This study aimed to design and prototype TELE-TOC (Telehealth Education: Leveraging Electronic Transitions of Care), a post-discharge, in-home, televisit intervention, and to map its workflow to ensure integration into the routine discharge care transition process for patients with COPD.

METHODS: A user-centered design approach across 3 phases was followed to develop and prototype TELE-TOC. Participants included …

School And District Leaders’ Understanding Of Technology Organizations’ Cyber Business Practices, Jayejaye Johnson

Journal of Educational Research and Practice

Educational technology (EdTech) interoperability throughout cyberspace provides the financial opportunity to collect and sell student privacy information in digital learning environments, challenging school leaders to govern schools and keep children safe. School leaders provide the resources, funding, planning, decision making, and administration for EdTech cybersecurity practices and policies, yet little is known about what public school leaders understand. A quantitative study was designed using primary data collected from an online survey. Four research questions guided this study: What are the differences in cybersecurity practices and policy response scores (1) between male and female school leaders; (2) among leaders with different …

Child Assent Practices In Research: Improving Ethics, Decision-Making, And Inclusivity, David C. Coker, Ketaki Inamdar, Daniel F. Mccleary, Lesley Cottrell

Journal of Educational Research and Practice

The following article addresses a conundrum: What if child assent in research were a fully informed, stand-alone process that empowered all children to discuss meaningfully, negotiate, and decide how and what the research experience would look like? Past research and practices suggest that child assent, when children (youths to 17-year-olds who have not been emancipated) agree to participate in research before, during, and after parents’ or guardians’ consent, is rife with problems that minimize informed participation and prize procedural ethics over true understanding of the processes and autonomous decision-making. Academic articles often lack details, as length requirements and brevity preclude …

Estate Planning Techniques: Disclaimer-A Useful Post-Mortem Estate Planning Tool, Philip E. Heckerling

Tax Adviser

No abstract provided.

Tax System As An Economic Force, Norman B. Ture

Tax Adviser

No abstract provided.

Various Tax Reform Provisions Affecting Individuals, Stuart R. Josephs

Tax Adviser

No abstract provided.

Charitable Contributions Under The Tax Reform Act Of 1969, Leonard A. Rapoport

Tax Adviser

No abstract provided.

Extensions And Expansions Of Ubit, Levon C. Register

Tax Adviser

No abstract provided.

Checklist For Foundation Managers Under The Tax Reform Act Of 1969, T. Milton Kupfer

Tax Adviser

No abstract provided.

Wired Differently, Not Broken, Abdullah Imran

Showcase of Scholars

No abstract provided.

How Racialized Language Sustains The “Illegal Hispanic” Stereotype, Amaya Arellano

Showcase of Scholars

No abstract provided.

Create @ State 2011, Arkansas State University - Jonesboro

Create@State

The proceedings book for 2011

Enrolled Deeds As Records And Archives In Jamaica, Andrew Williams

Journal of Contemporary Archival Studies

This paper examines the history of the enrolled deeds record series in Jamaica, from its creation in the mid-seventeenth century through to the present day. It is a critical examination of a single record series through colonialism and independence. It examines the purpose of deeds and the context in which deeds registries were created before examining the history of the series through the periods of slavery and emancipation. It examines in close detail the late nineteenth century, when the Island Record Office—which has custody of the enrolled deeds—was created and several other important changes happened. It situates the enrolled deeds …

Enhancing Archives And Records Management In Low-Resourced Organizations Through Experiential Learning, Jinfang Niu

Journal of Contemporary Archival Studies

Master’s students in Archives and Records Management could help low-resourced organizations address their Archives and Records Management needs while gaining practical experience. Archives and Records Management education programs could facilitate this mutually beneficial relationship by offering internships and service-learning courses. This paper analyzes the strengths and limitations of these two experiential learning mechanisms and discusses solutions to overcome the limitations. It argues that service-learning is especially suitable for addressing the Archives and Records Management needs of low-resourced organizations and proposes a service-learning model for that purpose.

Student-Designed Archival Pedagogy: A Workshop-As-Research Approach To Pluralizing Community Archives Education, Magdalena Wiśniewska-Drewniak

Journal of Contemporary Archival Studies

Community archives are becoming an increasingly important component of the heritage landscape, as well as an observable part of university archival education. This article is part of a research project titled “Teaching about Community Archives in the US and Poland--A Comparative Study” conducted by the author between March and May 2024. Using the student-centered learning approach, the article analyzes a workshop conducted with US-based students on the design of university courses on community archives. The designs included course audience, learning outcomes, course content, grading methods, and possible challenges. The article identifies four groups of learning outcomes (directions of community archives …