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Mechanisms Of Organisational Learning In Hospitals: An Instrument Development Study, Bret Lyman, Emily L. Smith, Kaitlyn C. George Mar 2022

Mechanisms Of Organisational Learning In Hospitals: An Instrument Development Study, Bret Lyman, Emily L. Smith, Kaitlyn C. George

Faculty Publications

Aim: To develop a valid, reliable research instrument to measure mechanisms associated with organisational learning in hospitals.

Background: A valid, reliable instrument for measuring mechanisms of organisational learning would enable nurse leaders and researchers to improve health care through facilitation and study of organisational learning.

Methods: The Organizational Learning in Hospitals model was used as a framework to develop the Organizational Learning Instrument-Mechanisms. Cognitive interviews and expert reviews were used to refine and evaluate item-level and scale-level content validity. The instrument was distributed by email to a random sample of nurses working in inpatient hospitals in Utah (n = 1253). …


Expanding Immigrant Justice By Training Professionals, Michele R. Pistone Mar 2022

Expanding Immigrant Justice By Training Professionals, Michele R. Pistone

Faculty Publications

As a law professor at Villanova University, I headed a clinic that helps hundreds of asylum seekers gain protection in the United States. On good days, I would remember the Talmudic saying, “whoever saves one life saves the world entire,” and take great pride in what my students and I were able to accomplish. On bad days, however, the fruits of our work could seem but a drop in the bucket, for every visit to immigration court demonstrated anew that our clients were the exception. Most immigrants face the immigration system without legal representation of any sort. This unfortunate and …


Fort Hays State University Tiger Weekly, March 11, 2022, University Relations Mar 2022

Fort Hays State University Tiger Weekly, March 11, 2022, University Relations

Tiger Weekly Newsletters

No abstract provided.


Iowa Wine Industry And Its Educational Needs, Aude A. Watrelot Mar 2022

Iowa Wine Industry And Its Educational Needs, Aude A. Watrelot

Journal of Extension

The grape and wine industry in Iowa is based on non-Vitis vinifera grapes, which are not well-known and come with their own set of challenges. An industry survey revealed that wine business and marketing are the main concerns for the Iowa grape and wine industry members. The educational resources already provided by Extension personnel were highly appreciated and events should be offered in several locations around Iowa. The main topics of roundtables and discussions should be about vineyard management and winemaking practices, specifically practices to avoid microbial spoilage, to reduce wine acidity and to select appropriate yeasts for fermentation.


Adjudicating Identity, Laura Lane-Steele Mar 2022

Adjudicating Identity, Laura Lane-Steele

Texas A&M Law Review

Legal actors examine identity claims with varying degrees of intensity. For instance, to be considered “female” for the U.S. Census, self-identification alone is sufficient, and no additional evidence is necessary. To change a sex marker on a birth certificate to “female,” however, self-identification is not enough; some states require people to show that they do not have a penis to be considered “female.” Similar examples of discrepancies in the type and amount of evidence considered for identity claims abound across identities and areas of law. Yet legal actors rarely acknowledge that they are adjudicating identity in the first place, much …


If Past Is Prologue, Then The Future Is Bleak: Contracts, Covid–19, And The Changed Circumstances Doctrines, Danielle K. Hart Mar 2022

If Past Is Prologue, Then The Future Is Bleak: Contracts, Covid–19, And The Changed Circumstances Doctrines, Danielle K. Hart

Texas A&M Law Review

At the heart of most of the systemic problems currently confronting individuals and businesses as a result of the COVID–19 pandemic is quite literally a contract. Housing. Insurance. Food. Health care. Child care. Employment. Manufacturing. Construction. Supply chains. You name it. Contracts are implicated everywhere. So make no mistake: How contract law addresses these ostensibly private contracts will have profound social consequences. If the past really is prologue, then the future is indeed bleak. The empirical study conducted for this Article establishes what the conventional wisdom has claimed for the last 70 years. More specifically, the empirical study here shows …


Sharpening The Focus Of Free Speech Law: The Crucial Role Of Government Intent, R. George Wright Mar 2022

Sharpening The Focus Of Free Speech Law: The Crucial Role Of Government Intent, R. George Wright

Texas A&M Law Review

Contemporary free speech law is typically misfocused. This misfocus serves neither the purposes underlying the institution of free speech nor any broader social rights and interests in conflict with freedom of speech. As a general matter, the adjudication of free speech claims should properly focus, centrally, on the intent of the regulating government. More specifically, courts should focus crucially on whether the government has, in enacting or enforcing its speech regulation, intended to suppress or disadvantage a presumed or actual idea or its expression. This sharpened focus would allow the courts to responsibly address a surprisingly broad range of free …


Ending The Charade: The Fifth Circuit Should Expressly Adopt The Deliberate Indifference Standard For Ada Title Ii And Ra Section 504 Damages Claims, Derek Warden Mar 2022

Ending The Charade: The Fifth Circuit Should Expressly Adopt The Deliberate Indifference Standard For Ada Title Ii And Ra Section 504 Damages Claims, Derek Warden

Texas A&M Law Review

While the Americans with Disabilities Act (“ADA”) has been law for over 30 years, the Fifth Circuit Court of Appeals has yet to adopt a definitive standard for how plaintiffs win damages under Title II of that law. Further, while the Rehabilitation Act (“RA”) has been law for almost 50 years, the Fifth Circuit has failed to announce any specific standard for how plaintiffs obtain damages under that law as well. I previously wrote an article in the pages of this journal that sought to “clarify” the Fifth Circuit’s jurisprudence on the issue. In Fifth Indifference: Clarifying the Fifth Circuit’s …


Fintech And Anti-Money Laundering Regulation: Implementing An International Regulatory Hierarchy Premised On Financial Innovation, Nicholas A Roide Mar 2022

Fintech And Anti-Money Laundering Regulation: Implementing An International Regulatory Hierarchy Premised On Financial Innovation, Nicholas A Roide

Texas A&M Law Review

Innovations in financial technology (“fintech”) have rippling effects across global markets. Fintech firms utilizing virtual assets and disintermediating blockchain technology continue to rapidly grow in strength and number. As systemic risk mounts due to the inter-jurisdictional nature of fintech, antimony laundering (“AML”) regulators must search for an international answer to maintain global financial stability and protect consumers against illicit activities. A variety of solutions have appeared within local AML regulatory frameworks. These frameworks tend to function as a hierarchy with three ordered objectives: market integrity, rule clarity, and innovation. However, frameworks often place too much emphasis on market integrity and …


Courting Prom Night Voters, Spencer Ryan Lockwood Mar 2022

Courting Prom Night Voters, Spencer Ryan Lockwood

Texas A&M Law Review

A creature of state law, voter registration is a point of national contention and a subject that frequents partisan debate. Federal legislation—meant to unsew a patchwork quilt of discriminatory practices against voters—complicated the voter registration process. States have changed their voter registration laws in the wake of Supreme Court opinions and prolonged litigation. But an opportunity endures for states to take further accountability for their younger voting-age populations without more federal intervention. By amending their election codes to require that high school graduates choose whether to register to vote, states can act as legislative laboratories and court their prom night …


Nurse Practitioner Role Perception, Job Satisfaction, And Anticipated Turnover In The Middle Atlantic States, Jenna R. Sabatino Mar 2022

Nurse Practitioner Role Perception, Job Satisfaction, And Anticipated Turnover In The Middle Atlantic States, Jenna R. Sabatino

Seton Hall University Dissertations and Theses (ETDs)

Background: The need for nurse practitioners (NPs) in the US has become very evident in recent years. However, the established significance of NPs in the healthcare system does not ensure that NPs are satisfied with their role. To date, no studies have examined NP job satisfaction in the Middle Atlantic States (MAS), which includes New York, New Jersey, and Pennsylvania. Only one study, thus far, has looked at NP role perception from the NPs own perspective, and was completed in the Midwest region of the US. Similarly, no studies have examined NP anticipated turnover the Mid-Atlantic region of the US. …


The Relationship Of Instructional Time On High School Students' Mathematical Achievement In The State Of New Jersey, Natalie Diaz Mar 2022

The Relationship Of Instructional Time On High School Students' Mathematical Achievement In The State Of New Jersey, Natalie Diaz

Seton Hall University Dissertations and Theses (ETDs)

This non-experimental quantitative study sought to analyze the relationship between instructional time and high school students' mathematical achievement as measured by the 2019 New Jersey Student Learning Assessment (NJSLA) for Algebra 1. In addition to determining to which extent the district factor groups (DFGs) affect the relationship between instructional time on the performance of high school students on the 2019 New Jersey Student Learning Assessment (NJSLA) for Algebra 1 when controlling for staff, student, and school variables. The 2018–2019 NJDOE Performance Report provided the variables used in this study. The unit of analysis was public high schools in New Jersey …


Radiv1: A Non-Steady-State Early Diagenetic Model For Ocean Sediments In Julia And Matlab/Gnu Octave, Olivier Sulpis, Matthew P. Humphreys, Monica M. Wilhelmus, Dustin Carroll, William M. Berelson, Dimitris Menemenlis, Jack J. Middelburg, Jess F. Adkins Mar 2022

Radiv1: A Non-Steady-State Early Diagenetic Model For Ocean Sediments In Julia And Matlab/Gnu Octave, Olivier Sulpis, Matthew P. Humphreys, Monica M. Wilhelmus, Dustin Carroll, William M. Berelson, Dimitris Menemenlis, Jack J. Middelburg, Jess F. Adkins

Faculty Research, Scholarly, and Creative Activity

We introduce a time-dependent, one-dimensional model of early diagenesis that we term RADI, an acronym accounting for the main processes included in the model: chemical reactions, advection, molecular and bio-diffusion, and bio-irrigation. RADI is targeted for study of deep-sea sediments, in particular those containing calcium carbonates (CaCO3). RADI combines CaCO3 dissolution driven by organic matter degradation with a diffusive boundary layer and integrates state-of-the-art parameterizations of CaCO3 dissolution kinetics in seawater, thus serving as a link between mechanistic surface reaction modeling and global-scale biogeochemical models. RADI also includes CaCO3 precipitation, providing a continuum between CaCO3 dissolution and precipitation. RADI integrates …


Ready To Serve: Opportunities For Cooperative Extension To Support Military Families, Rachel A. Brauner, Andrew B. Crocker Mar 2022

Ready To Serve: Opportunities For Cooperative Extension To Support Military Families, Rachel A. Brauner, Andrew B. Crocker

Journal of Extension

The issues families in the military experience have been exacerbated by 20 years of continuous war. Families in the military across all the service branches are families first, sharing similar struggles as their civilian counterparts. Like many families, families in the military have day-to-day concerns about health, financial management, parenting and building positive relationships. Cooperative Extension is positioned to bridge the gap between building support systems and providing quality education, services and care to service members and their families–but are we ready to serve?


Physiological Responses To Acute Cycling With Blood Flow Restriction, Matthew A. Kilgas, Tejin Yoon, John Mcdaniel, Kevin Phillips, Steve Elmer Mar 2022

Physiological Responses To Acute Cycling With Blood Flow Restriction, Matthew A. Kilgas, Tejin Yoon, John Mcdaniel, Kevin Phillips, Steve Elmer

Michigan Tech Publications, Part 1

Aerobic exercise with blood flow restriction (BFR) can improve muscular function and aerobic capacity. However, the extent to which cuff pressure influences acute physiological responses to aerobic exercise with BFR is not well documented. We compared blood flow, tissue oxygenation, and neuromuscular responses to acute cycling with and without BFR. Ten participants completed four intermittent cycling (6 × 2 min) conditions: low-load cycling (LL), low-load cycling with BFR at 60% of limb occlusion pressure (BFR60), low-load cycling with BFR at 80% of limb occlusion pressure (BFR80), and high-load cycling (HL). Tissue oxygenation, cardiorespiratory, metabolic, and perceptual responses were assessed during …


Assessment Of Diversity Of Antimicrobial Resistance Phenotypes And Genotypes Of Mannheimia Haemolytica Isolates From Bovine Nasopharyngeal Swabs, Hannah F. Carter, Robert W. Wills, Matthew A. Scott, Alexis C. Thompson, Randall S. Singer, John Dustin Loy, Brandi B. Karisch, William B. Epperson, Amelia R. Woolums Mar 2022

Assessment Of Diversity Of Antimicrobial Resistance Phenotypes And Genotypes Of Mannheimia Haemolytica Isolates From Bovine Nasopharyngeal Swabs, Hannah F. Carter, Robert W. Wills, Matthew A. Scott, Alexis C. Thompson, Randall S. Singer, John Dustin Loy, Brandi B. Karisch, William B. Epperson, Amelia R. Woolums

School of Veterinary and Biomedical Sciences: Faculty Publications

The threat of bovine respiratory disease (BRD) for cattle operations is exacerbated by increasing prevalence of antimicrobial resistance (AMR) in Mannheimia haemolytica, a leading cause of BRD. Characterization of AMR in M. haemolytica by culture and susceptibility testing is complicated by uncertainty regarding the number of colonies that must be selected to accurately characterize AMR phenotypes (antibiograms) and genotypes in a culture. The study objective was to assess phenotypic and genotypic diversity of M. haemolytica isolates on nasopharyngeal swabs (NPS) from 28 cattle at risk for BRD or with BRD. NPS were swabbed onto five consecutive blood agar plates; …


Factors And Processes That Influence E-Professionalism Among Pre-Licensure Baccalaureate Nursing Students When Utilizing Social Media, Julie Skrabal Mar 2022

Factors And Processes That Influence E-Professionalism Among Pre-Licensure Baccalaureate Nursing Students When Utilizing Social Media, Julie Skrabal

Dissertations

There is limited research related to nursing students' social media use. Because of this, there was a need to further explore how they were using social media and their ability to maintain e-professionalism. This study discovered that pre-licensure baccalaureate nursing students are actively using multiple social media accounts on a daily basis. Nursing is considered a trusted and respected profession, therefore, nursing students are held to a high professional standard. This includes maintaining privacy boundaries when managing professional and personal information during social media use.

The purpose of this grounded theory study was to explore the processes pre-licensure baccalaureate nursing …


Thiomicrorhabdus Heinhorstiae Sp. Nov. And Thiomicrorhabdus Cannonii Sp. Nov.: Novel Sulphur-Oxidizing Chemolithoautotrophs Isolated From The Chemocline Of Hospital Hole, An Anchialine Sinkhole In Spring Hill, Florida, Usa, Tatum Updegraff, Grayson Schiff-Clark, Hunter Gossett, Sheila Parsi, Rebecca Peterson, Robert Whittaker, Clare Dennison, Madison Davis, James Bray, Rich Boden, Kathleen Scott Mar 2022

Thiomicrorhabdus Heinhorstiae Sp. Nov. And Thiomicrorhabdus Cannonii Sp. Nov.: Novel Sulphur-Oxidizing Chemolithoautotrophs Isolated From The Chemocline Of Hospital Hole, An Anchialine Sinkhole In Spring Hill, Florida, Usa, Tatum Updegraff, Grayson Schiff-Clark, Hunter Gossett, Sheila Parsi, Rebecca Peterson, Robert Whittaker, Clare Dennison, Madison Davis, James Bray, Rich Boden, Kathleen Scott

School of Biological and Marine Sciences

Two sulphur-oxidizing, chemolithoautotrophic aerobes were isolated from the chemocline of an anchialine sinkhole located within the Weeki Wachee River of Florida. Gram-stain-negative cells of both strains were motile, chemotactic rods. Phylogenetic analysis of the 16S rRNA gene and predicted amino acid sequences of ribosomal proteins, average nucleotide identities, and alignment fractions suggest the strains HH1T and HH3T represent novel species belonging to the genus Thiomicrorhabdus. The genome G+C fraction of HH1T is 47.8 mol% with a genome length of 2.61 Mb, whereas HH3T has a G+C fraction of 52.4 mol% and 2.49 Mb genome length. Major fatty acids of the …


Deepreal: A Deep Learning Powered Multi-Scalemodeling Framework For Predicting Out-Of-Distributionligand-Induced Gpcr Activity, Tian Cai, Kyra Alyssa Abbu, Yang Liu, Lei Xie Mar 2022

Deepreal: A Deep Learning Powered Multi-Scalemodeling Framework For Predicting Out-Of-Distributionligand-Induced Gpcr Activity, Tian Cai, Kyra Alyssa Abbu, Yang Liu, Lei Xie

Publications and Research

Motivation Drug discovery has witnessed intensive exploration of predictive modeling of drug–target physical interactions over two decades. However, a critical knowledge gap needs to be filled for correlating drug–target interactions with clinical outcomes: predicting genome-wide receptor activities or function selectivity, especially agonist versus antagonist, induced by novel chemicals. Two major obstacles compound the difficulty on this task: known data of receptor activity is far too scarce to train a robust model in light of genome-scale applications, and real-world applications need to deploy a model on data from various shifted distributions.

Results To address these challenges, we have developed an end-to-end …


Elements Of Instagram Influencer Posts That Drive Follower Engagement, Yishan Li Mar 2022

Elements Of Instagram Influencer Posts That Drive Follower Engagement, Yishan Li

USF Tampa Graduate Theses and Dissertations

Influencers are now becoming more popular on social media as a way for brands to promote products and services. The relationship between influencers’ post content and follower engagement deserves more attention. Through a content analysis, this research examines how influencer posts drive follower engagement. The results showed that emojis, campaign hashtags, frequency, and sponsored tags had a significant relationship with follower engagement. The present study sheds light on future research to explore other content variables of influencers’ posts.


The Last Conversation, Muhammad Ismail Khalid Yousaf Mar 2022

The Last Conversation, Muhammad Ismail Khalid Yousaf

Journal of Wellness

The brain-death exam is one of the most sensitive undertakings for a physician, especially a neurologist, because of its social and legal implications. It is the vital examination establishing a clear lack of meaningful vitals, allowing a family to mark the end of a journey and a life finally complete. Physicians who perform and establish this death-decision must ensure they are au courant with the family's sentiments and concerns. It would behoove this obligated physician to bear in mind that it is a human being who will go through this invasive and rough exam. This comatose person is a father …


Tools For Healthy Living: Lessons Learned About Program Efficacy, Youth Knowledge, And Youth Engagement, Sharon Gray, Jennifer Cushman, Miriah Kelly, Mary Margaret Gaudio, E. Jean Gubbins Mar 2022

Tools For Healthy Living: Lessons Learned About Program Efficacy, Youth Knowledge, And Youth Engagement, Sharon Gray, Jennifer Cushman, Miriah Kelly, Mary Margaret Gaudio, E. Jean Gubbins

Journal of Extension

Youth in grades 4 to 6 were presented with healthy living topics through a two cycle, 11-week 4-H after school curriculum designed for low income, urban populations. Pre- and post-surveys were used to measure knowledge of healthy homes topics such as mold and moisture, lead poisoning, pests, asthma triggers, smoking, and food safety. Daily journaling activities designed to measure youth engagement also added to the mixed data set. Lessons learned about program efficacy, youth knowledge, and youth engagement are presented.


Water Conservation: Extension Agents’ Perceptions Of Issue Importance, Professional Abilities, And Landowner Needs, Audrey Mccrary, Leslie M. Burger, Laura Downey, Beth H. Baker Mar 2022

Water Conservation: Extension Agents’ Perceptions Of Issue Importance, Professional Abilities, And Landowner Needs, Audrey Mccrary, Leslie M. Burger, Laura Downey, Beth H. Baker

Journal of Extension

The Extension Service is one of many agencies charged with increasing awareness and knowledge of research-based agricultural conservation practices. A regional survey of Extension agents with agriculture and natural resources responsibilities was conducted to assess the need for in-service training on 11 water resource conservation topics. The highest priority training needs were for topics related to complex interactions and drivers of agricultural water pollution. This article highlights the implications of these results and offers broader perspective on bringing the Borich model of needs assessment into the agricultural and natural resources realm of subject matter expertise.


The Impact Of The Covid-19 Pandemic On Healthy Lifestyles In Rural Families., Keisha M. England, Bethany Forseth Hanson, Maheen Bangash, Rohit Bhagat, Megan Murray, Dana Bakula, Ann M. Davis Mar 2022

The Impact Of The Covid-19 Pandemic On Healthy Lifestyles In Rural Families., Keisha M. England, Bethany Forseth Hanson, Maheen Bangash, Rohit Bhagat, Megan Murray, Dana Bakula, Ann M. Davis

Manuscripts, Articles, Book Chapters and Other Papers

The purpose of the current study is to understand how the early portion of COVID-19 pandemic impacted the health behaviors of rural families participating in a healthy lifestyles intervention. Caregivers of rural children participating in a healthy lifestyles intervention were invited to participate in a structured interview regarding how the COVID-19 pandemic affected their family and family health behaviors. Interviews were transcribed and the research team conducted a rigorous inductive thematic analysis. Structured qualitative interviews with caregivers (n=30) resulted in 5 saturated themes: (a) caregivers reported new or exacerbated mental health concerns and stress among family members, largely due to …


Towards A Biological Definition Of Ards: Are Treatable Traits The Solution?, Lieuwe D J Bos, John G Laffey, Lorraine B Ware, Nanon F L Heijnen, Pratik Sinha, Brijesh Patel, Matthieu Jabaudon, Julie A Bastarache, Daniel F Mcauley, Charlotte Summers, Carolyn S Calfee, Manu Shankar-Hari Mar 2022

Towards A Biological Definition Of Ards: Are Treatable Traits The Solution?, Lieuwe D J Bos, John G Laffey, Lorraine B Ware, Nanon F L Heijnen, Pratik Sinha, Brijesh Patel, Matthieu Jabaudon, Julie A Bastarache, Daniel F Mcauley, Charlotte Summers, Carolyn S Calfee, Manu Shankar-Hari

2020-Current year OA Pubs

The pathophysiology of acute respiratory distress syndrome (ARDS) includes the accumulation of protein-rich pulmonary edema in the air spaces and interstitial areas of the lung, variable degrees of epithelial injury, variable degrees of endothelial barrier disruption, transmigration of leukocytes, alongside impaired fluid and ion clearance. These pathophysiological features are different between patients contributing to substantial biological heterogeneity. In this context, it is perhaps unsurprising that a wide range of pharmacological interventions targeting these pathophysiological processes have failed to improve patient outcomes. In this manuscript, our goal is to provide a narrative summary of the potential methods to capture the underlying …


A Novel Proton-Integrating Radiography System Design Using A Monolithic Scintillator Detector: Experimental Studies, Chinmay D Darne, Daniel G Robertson, Fahed Alsanea, Charles-Antoine Collins-Fekete, Sam Beddar Mar 2022

A Novel Proton-Integrating Radiography System Design Using A Monolithic Scintillator Detector: Experimental Studies, Chinmay D Darne, Daniel G Robertson, Fahed Alsanea, Charles-Antoine Collins-Fekete, Sam Beddar

Faculty, Staff and Student Publications

Research on proton-based imaging systems aims to improve treatment planning, internal anatomy visualization, and patient alignment for proton radiotherapy. The purpose of this study was to demonstrate a new proton radiography system design consisting of a monolithic plastic scintillator volume and two optical cameras for use with scanning proton pencil beams. Unlike the thin scintillating plates currently used for proton radiography, the plastic scintillator volume (20 × 20 × 20 cm


Lonnie C. Fountain, Jr. Mar 2022

Lonnie C. Fountain, Jr.

African American Funeral Programs

No abstract provided.


Air Exchanges, Climate Change, And Severe Acute Respiratory Coronavirus Virus 2 (Sars-Cov-2): Results From A Survey Of The Society Of Healthcare Epidemiology Of America Research Network (Srn), Jason P. Burnham, Fred Betz, Roger Lautz, Ehsan Mousavi, Richard A. Martinello, Forbes Mcgain, Jodi D. Sherman Mar 2022

Air Exchanges, Climate Change, And Severe Acute Respiratory Coronavirus Virus 2 (Sars-Cov-2): Results From A Survey Of The Society Of Healthcare Epidemiology Of America Research Network (Srn), Jason P. Burnham, Fred Betz, Roger Lautz, Ehsan Mousavi, Richard A. Martinello, Forbes Mcgain, Jodi D. Sherman

Open Access Publications

No abstract provided.


Exploiting Radiation Induction Of Antigens In Cancer: Targeted Drug Delivery, Vaishali Kapoor, Abhay K Singh, Calvin D Lewis, Sapna Deore, Dennis E Hallahan Mar 2022

Exploiting Radiation Induction Of Antigens In Cancer: Targeted Drug Delivery, Vaishali Kapoor, Abhay K Singh, Calvin D Lewis, Sapna Deore, Dennis E Hallahan

Open Access Publications

Therapeutic antibodies used to treat cancer are effective in patients with advanced-stage disease. For example, antibodies that activate T-lymphocytes improve survival in many cancer subtypes. In addition, antibody-drug conjugates effectively target cytotoxic agents that are specific to cancer. This review discusses radiation-inducible antigens, which are stress-regulated proteins that are over-expressed in cancer. These inducible cell surface proteins become accessible to antibody binding during the cellular response to genotoxic stress. The lead antigens are induced in all histologic subtypes and nearly all advanced-stage cancers, but show little to no expression in normal tissues. Inducible antigens are exploited by using therapeutic antibodies …


A Statistical Principal Component Regression-Based Approach To Modeling The Degradative Effects Of Local Climate And Traffic On Airfield Pavement Performance, Evan M. Fortney, Steven J. Schuldt, Sarah L. Brown, James P. Allen, Justin D. Delorit Mar 2022

A Statistical Principal Component Regression-Based Approach To Modeling The Degradative Effects Of Local Climate And Traffic On Airfield Pavement Performance, Evan M. Fortney, Steven J. Schuldt, Sarah L. Brown, James P. Allen, Justin D. Delorit

Faculty Publications

Airfield pavement systems support the global economy, passenger travel, and national defense. Accurate pavement degradation predictions are critical inputs for maintenance and repair decisions, and when skillful, they may reduce the need for time-intensive, costly physical inspections that disrupt airfield operations. Existing airport pavement management systems (APMS) compute expected degradation as a function of pavement type and age, but they do not account for local climate and traffic conditions and they are not built to adapt to future changes in either mode of variability. This paper implements a bias-reduced statistical model that reveals the effects of local conditions using observed …