Digital Commons Network^™

Relationship Between Teacher Psychological Safety And Perceived Administrator Support In Independent Schools, Kim Schinzel

Walden Dissertations and Doctoral Studies

No abstract provided.

Pathogenic Variants In The Cohesin Loader Subunit Mau2 Underlie A Distinct Cornelia De Lange Syndrome Subtype., Ilaria Parenti, Alina Hesters, Marta Gil-Salvador, Laura Duffy, Deniz Kanber, Jasmin Beygo, Jennifer Kerkhof, Laura Steenpaß, Elsa Leitão, Julia Woestefeld, Philip M. Boone, Emeline M. Kao, Lama Alabdi, Hesham M. Aldhalaan, Fowzan S. Alkuraya, Muneera J. Alshammari, Stylianos E. Antonarakis, Donald Basel, Kevin Cassinari, Laurana De Polli Cellin, Amanda R. Clause, Alexander Augusto De Lima Jorge, Andréa De Castro Leal, Stephan C. Collins, Benjamin Durand, Juliane Eckhold, Mais O. Hashem, Parul Jayakar, Arif O. Khan, Kohji Kato, Regina Kubica, Gholson J. Lyon, Elaine Marchi, Julie Mccarrier, Lara K. Kimmig, Seiji Mizuno, Gael Nicolas, Yosuke Nishio, Tomoo Ogi, Juan Pié, Jordyn Prell, Beatriz Puisac, Feliciano J. Ramos, Emmanuelle Ranza, Claire Redin, Eric T. Rush, Shinji Saitoh, Hanan E. Shamseldin, Susan Starling, Esteban Astiazaran-Symonds, Sara H. Eltahir, Alma Kuechler, Bekim Sadikovic, Binnaz Yalcin, Kerstin S. Wendt, Frank J. Kaiser

Manuscripts, Articles, Book Chapters and Other Papers

The role of the cohesin complex depends on the cohesin loader proteins NIPBL and MAU2. While NIPBL variants are a major cause of Cornelia de Lange Syndrome (CdLS), the role of MAU2 in disease is unclear. We describe 18 individuals carrying 15 heterozygous MAU2 variants and demonstrate pathogenicity through functional analyses. In-frame MAU2 variants predominantly impair NIPBL-MAU2 interaction, whereas truncating variants cause MAU2 haploinsufficiency and lead to NIPBL reduction. Most individuals exhibit a DNA methylation profile compatible with the CdLS episignature. We also describe two MAU2-specific episignatures that reflect variant-dependent molecular consequences. Affected individuals display a wide range of phenotypes, …

Morphological Characteristics Of The Mediophyceae Diatom Lampriscus Cf. Shadboltianus Var. Crenulatus Collected From Gili Meno, Indonesia, Arief Rachman, Riani Widiarti, Setiarti Sukotjo, Mark Wells

Makara Journal of Science

Diatoms are the most common and abundant microalgae group in seawater, with an estimated 200 genera and 200,000 species categorized into three distinct taxonomic classes: Mediophyceae, Bacillariophyceae, and Coscinodiscophyceae. This study describes the morphological characteristics of Lampriscus GM052022, a diatom belonging to the Mediophyceae family, which was collected from Gili Matra, Lombok, Indonesia. Analysis using light microscopy (LM) and electron microscopy (EM) showed that the morphological characteristics of the Lampriscus GM052022 specimen are similar to those of Lampriscus shadboltianus var. crenulatus due to the distinct crenulation lines on the frustule, which differentiate this variation from Lampriscus shadboltianus. However, the …

In Vitro And In Silico Analysis Of The Antibacterial Activity Of Bioactive Compounds Extracted From Pineapple Peel, Wafa Mohammad Sadik, Iman Tajer Abdullah, Lana Abed Alnajar

Makara Journal of Science

Antibiotic resistance is a critical global challenge that requires the discovery of alternative therapeutic agents. Plants -derived compounds, such as those found in Ananas comosus (pineapple)peel, offer promising antibacterial potential. This study aimed to evaluate the antibacterial activity of pineapple peel extract using both in vitro and in silico approaches. Ethanolic extracts of pineapple peel were fractionated using silica gel chromatography, and the resulting fractions were analyzed by GC-MS. Antibacterial activity was tested against Gram-positive and Gram-negative pathogens using the agar well diffusion method, and the inhibition zones were recorded. Molecular docking was performed to assess the interaction of identified …

Phytochemistry And Pharmacological Activities Of Sphagneticola Trilobata: A Systematic Review With Perspectives For Drug Discovery, Sonali Dnyaneshwar Labhade, Suraj Kamadi, Pawan Nandkishor Karwa, Ritesh Prakash Bhole, Harshad Sunil Kapare, Sohan Satyanarayan Chitlange

Makara Journal of Science

Sphagneticola trilobata (L.) Pruski is a medicinal plant widely used in traditional medicine for its anti-inflammatory, antimicrobial, antioxidant, hepatoprotective, wound healing, and CNS depressant effects. Despite its broad pharmacolo-gical potential, clinical application is limited due to a lack of mechanistic understanding, standardization, and clinical validation. This review aims to provide a comprehensive overview of the phytochemical composition, pharmacological activities, and therapeutic potential of S. trilobata, while highlighting research gaps and suggesting future directions for clinical translation. A systematic review of scientific literature, ethnobotanical sources, and pharmacological studies was conducted, focusing on phytochemical analysis, biological activity, toxicity, and potential applications …

Multiplex Functional Assessment Of Variant Effect In The Retinal Transcription Factor Crx, James Lewis Shepherdson

Arts & Sciences Graduate Student Theses and Dissertations

The transcription factor Cone-Rod Homeobox (CRX) is a master regulator of photoreceptor cell fate. Sequence variants in CRX can cause Retinitis Pigmentosa, Cone-Rod Dystrophy, and Leber Congenital Amaurosis, all inherited causes of vision loss and blindness. CRX is the only gene implicated in the pathogenesis of all three of these diseases, which present with both rod- and cone-centric phenotypes of varying age of onset and severity. Several CRX variants have been reported to cause severe dominant disease through antimorphic genetic interactions with wild-type CRX, and yet these mutations are adjacent to variants which are benign or only cause mild, recessive …

Exploring The Process Of Using Equine-Assisted Psychotherapy To Treat Anxiety, Danica Yates

Walden Dissertations and Doctoral Studies

Anxiety is the most rapidly growing mental health problem globally, particularly among adolescents and young adults. Mental health clinicians need effective integrative health treatment strategies to address the anxiety epidemic. The purpose of this qualitative generic study was to explore the perspectives of clinicians on the process of using equine-assisted psychotherapy (EAP) to treat adolescents and young adults with anxiety through the lens of a somatic theory, bioenergetics. Data were collected using semi-structured interviews with 12 EAP clinicians and analyzed using Braun and Clarke’s thematic analysis. Three themes were identified: 1. The process of EAP is highly effective because energetic …

Patterns Of Multimorbidity Among Low-Income Adults Who Smoke With Implications For Tailored Interventions: A Cluster Analysis Using A Mixture Of Bernoulli Model, Monique T. Cano, Michael R. Lindstrom, Oscar F. Rojas Perez, Ricardo F. Muñoz

School of Mathematical & Statistical Sciences Faculty Publications

Introduction: Smoking cigarettes remains a leading modifiable risk factor for preventable health conditions. In the United States, the health burden of smoking disproportionately impacts low-income individuals. Multimorbidity is common in this group, complicating treatment and worsening outcomes. Identifying multimorbidity clusters can support targeted, individualized interventions. This study aimed to identify multimorbidity clusters among individuals who smoke and experience economic hardship and provide clinical recommendations to enhance health outcomes.

Method: Individuals who smoke and experience economic hardship (N = 60) were recruited from the San Francisco Health Network (SFHN) and were assessed for physical and mental conditions. Cluster analysis was …

Prevalence And Determinant Factors Of Depression Among Pregnant Women In Poned Health Center In Tangerang City Area, Dian Geumala Hayati, Sudijanto Kamso, Popy Yuniar, Yuli Puspita Devi

Jurnal Epidemiologi Kesehatan Indonesia

According to World Health Organization (WHO), approximately 10% of pregnant women experience mental disorders, with depression being particularly prevalent. In developing countries, this rate is was even higher, reaching 19.8% after childbirth and 15.6% during pregnancy. Various studies conducted in Indonesia show that the prevalence of depression among pregnant women ranges widely, from 21.4% to 26.2%.This study aimed to determine the prevalence and risk factors associated with depression during pregnancy in pregnant women at the PONED Community Health Center in Tangerang City Area. A facility-based cross-sectional study was conducted with 105 pregnant women attending antenatal check-ups at the 17 PONED …

Dawes, Trevor A. And Michael J. Krasulski, Eds. Twenty-First-Century Access Services: On The Front Line Of Academic Librarianship, Second Edition. Chicago: Association Of College And Research Libraries, 2023., Alyssa Ohlhauser

The Christian Librarian

No abstract provided.

Social Science Research: From Publication To Application, Maria Caridad H. Tarroja

Asia-Pacific Social Science Review

No abstract provided.

The Influence Of Demographic Factors On Smoking Behavior Among Low-Income Forest Farmers: Evidence In West Java And Nusa Tenggara Provinces, Indonesia, Budiman Achmad, Dian Diniyati, Eva Fauziyah, Subarudi Subarudi, Mudji Susanto, Danarti Danarti, Rukmini Nugroho Dewi, Sri Najiyati, I Gusti Ayu Putu Mahendri, Tota Suhendrata, Demas Wamaer, Joula Olvy Maya Sondakh, Ratna Ayu Saptati

Asia-Pacific Social Science Review

Smoking constitutes a significant issue in Indonesia, particularly among low-income forest farmers. Cigarettes are the second-highest household expenditure after rice, potentially comprising almost 40% of total annual income. In 2022, the prevalence of smokers aged 15 years and older was recorded at 28.26%, with West Nusa Tenggara ranking second (26.59%). This situation exacerbates poverty and reduces the quality of human resources. The study was conducted in 2023 in Ciamis Regency, Tasikmalaya (West Java), and Sumbawa (West Nusa Tenggara), areas with high cigarette consumption. The aim was to analyze the influence of demographic factors (income, age, and education) on smoking behavior …

Learner Leadership Practices And Student Behavior: A Cultivation Of Student Leadership, Sarun Widtayakornbundit, Jie Hu

Asia-Pacific Social Science Review

This study explored how student leadership practices (SLP) are essential in shaping learners’ development and their continued engagement with higher education institutions. This research investigates the direct and indirect effects of SLP on affective commitment (AC), employing self-efficacy (SE), individualism (IND), and collectivism (COL) as mediating variables. Data were collected through a structured online survey administered to undergraduate students from 11 public universities in Guangxi, China. The study received 436 responses and 387 valid cases. The Student Leadership Practices Inventory, the General Self-Efficacy Scale, the Individualism–Collectivism Scale, and the Affective Commitment Scale were all used as standardized tools. The analysis …

Revisiting The Double Movement In Development: A Systematic Review Of Polanyian Counter-Movements, Yuli Isnadi, Asmarawati Handoyo, Chin-Fu Hung

Asia-Pacific Social Science Review

The concept of the double movement, as expounded by Polanyi (1944/2001), has been a focal point of interest for numerous scholars. However, it is evident that more concerted efforts are required to foster a substantive dialogue among these scholars. Goodwin (2018) took a significant step by initiating a constructive discussion aimed at revitalizing the double movement theory, with the intent of rendering it pertinent to addressing the socioeconomic challenges faced by societies in the Global South. Regrettably, Goodwin’s approach, which primarily leans towards a political system perspective, is not without its limitations. Therefore, this article proposes a societal approach that …

The Korean Welfare State: Social Investment In An Aging Society, Gholib Tamam Fauzi, Dwi Supatmi

Asia-Pacific Social Science Review

No abstract provided.

Comparative Antiscabies Efficacy Of Sonneratia Alba Extracts: Evaluation Of Plant Parts And Concentrations In Mice, Delima Engga Maretha, Lara Mukti Taresha, Karina Yuliana, Iis Ariska, Silvia Diah Lestari

Makara Journal of Science

This study evaluated the antiscabies efficacy of 70% ethanol extracts from various parts of the mangrove Sonneratia alba (leaves, flowers, bark, and roots) as a potential alternative therapy. The primary objective was to compare the healing effects of the extracts at different concentrations on scabies lesions in mice (Mus musculus). Using a completely randomized design, 24 male Swiss Webster mice were assigned to four groups: a control (K0) group and three treatment groups to receive 10% (K1), 20% (K2), and 30% (K3) extract concentrations topically twice daily. The results demonstrated that the S. alba extracts had significant effects …

Design And In Silico Modeling Of Heterocyclic-Based Xanthone Derivatives As Potential Anticancer Agents Through Tyrosine Kinase Inhibition, Yehezkiel Steven Kurniawan, Ervan Yudha, Nela Fatmasari, Radite Yogaswara, Harno Dwi Pranowo, Eti Nurwening Sholikhah, Jumina Jumina

Makara Journal of Science

Cancer is one of the deadliest diseases nowadays, and tyrosine kinase receptors play crucial roles in cancer cell survival, differentiation, proliferation, and migration. This study designed and developed a new inhibitor from heterocyclic-based xanthone derivatives to target two tyrosine kinase receptors, epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR), through in silico screening. Eighteen heterocyclic-based xanthones were evaluated through molecular docking for both receptors. All heterocyclic-based xanthones gave the root mean square deviation (RMSD) value lower than 2.00 Å. Xanthone with isobenzothiazole substituent (iBzThio) was found as the most potent inhibitor with binding energies of -10.60 and …

Application Of Microbial Fuel Cells For Leachate Bioremediation: The Effects Of Nutrient Nourishment, Umi Sholikah, Fidela Chosta, Tegar Palyus Fiqar, Eka Masrifatus Anifah, Riza Hudayarizka, Tadashi Hibino

Makara Journal of Science

Leachate contains a high organic content, which can cause environmental pollution. The organic content in leachate can be removed through bioremediation using microbial fuel cell (MFC) systems to remediate pollutants and generate bioelectricity. Organic matter is important to the MFC process as both a substrate and a nutrient source. This study investigated the effects of glucose and sodium phosphate buffer nourishment on BOD, COD, and TSS removal and bioelectricity generation. This study used leachate as a substrate and a graphite rod with a surface area of about 32.98 cm² as an electrode. The reactor uses plastic blocks with a …

Anthrone-Based Dummy Molecularly Imprinted Polymer For The Selective Detection Of Fluorene And Phenanthrene In Simulated River Water, Aria Pinandita, Nurrahmi Handayani, Muhammad Iqbal, Untung Triadhi, Rusnadi Rusnadi, Samitha Dewi Djajanti, Muhammad Bachri Amran, Muhammad Ali Zulfikar

Makara Journal of Science

A dummy-template molecularly imprinted polymer (DMIP) was synthesized via precipitation polymerization using anthrone as a template analog for the selective analysis of low-molecular-weight polycyclic aromatic hydrocarbons (PAHs), specifically fluorene and phenanthrene. Styrene, benzoyl peroxide, and ethylene glycol dimethacrylate were employed as the functional monomer, radical initiator, and crosslinking agent, respectively. The synthesized polymers were characterized by Fourier-transform infrared spectroscopy, scanning electron microscopy, and particle size analysis. The imprinting factors were 1.16 and 1.09 for fluorene and phenanthrene, respectively, indicating enhanced affinity of the imprinted sites. High-performance liquid chromatography analysis following DMIP-based solid-phase extraction yielded recoveries of 91.49% ± 3.87% for …

Strong Gravitational Lensing Of Balart-Vagenas Regular Black Holes, Akif Pervez, Hassan Moin Ud Din, Handika Satrio Ramdhan

Makara Journal of Science

Gravitational lensing is an integral part of Einstein general theory of relativity. The existence of singularity in standard black holes is a hurdle for understanding the properties of black holes. The introduction of nonlinear electrodynamics (NLED) offers an intriguing possibility of constructing non-singular black hole. Gravitational lensing by the photon sphere probes the physical properties of lens objects such as black holes. This work presents a strong deflection limit analysis in a general asymptotically flat, stationary, spherically symmetric spacetime. We extend the analysis of the light deflection around the photon sphere-complete capture, and set a strong field limit that is …

A Ferrocene-Modified Carbon Electrode Prepared From Coconut Shell Char For Cu(Ii) Detection In Water, Nabila Putri Aulia, Fitria Rahmawati, Abu Masykur, Eddy Heraldy

Makara Journal of Science

A ferrocene (Fc)-modified carbon electrode was prepared from coconut shell char (CSC), which was activated with NaOH to produce an activated coconut shell carbon (Ac-CSC). The carbon electrode was designed as a printed-carbon electrode consisting of working, counter and reference electrodes in a single piece, called a screen-printed carbon electrode, or SPCE. An Fc solution was applied to the working electrode part at 10%, 20% and 30% mass of the SPCE, producing an SPCE-Fc as an electrochemical sensor for Copper ions Cu(II) detection. The prepared activated carbon was analysed by XRD, FTIR, SEM/EDX, surface area analysis and impedance measurement to …

Dietary Oil From Hermetia Illucens L. Larvae Promotes Weight Gain And Alters Leukocyte Profiles In Mus Musculus L, Rudy Agung Nugroho Ran, Reni Kurniati, Widya Putri Ambar Sari, Reynaldo Imanuel Sompotan, Retno Aryani, Hetty Manurung, Rudianto Rudianto

Makara Journal of Science

The escalating global demand for high-quality animal-derived proteins has driven the search for sustainable alternatives. Black soldier fly larvae (BSFL; Hermetia illucens L.) oil presents a promising option, by addressing organic waste management while providing nutrient-rich feed. This study evaluated the effects of dietary supplementation with BSFL oil on growth performance, hematological characteristics, and blood lipid profiles in mice (Mus musculus). Male mice were randomly assigned to five groups (n = 5): positive control (fish oil, 5 mL/kg body weight [BW]), negative control (Aquadest, 5 mL/kg BW), and three treatment groups receiving BSFL oil at 2.5, 5, and …

Liparis Condylobulbon Reichb. F. From Gumitir, Indonesia: Morphology, Molecular, And Phytochemical Profile, Fuad Bahrul Ulum, Asyifa Yasmin Arum, Kurnia Sa’Adah, Dwi Setyati, Edia Fitria Dwinianti, Ranjithkumar Rajamani, Ari Satia Nugraha, Mukhamad Su’Udi

Makara Journal of Science

Liparis condylobulbon Rchb.f. is an epiphytic orchid across South and Southeast Asia, which holds notable ethnomedicinal and pharmacological significance. This study aims to characterize Indonesian Liparis condylobulbon using integrated morphological, molecular (matK, rbcL, ITS2), and phytochemical (LC-MS, DPPH) analyses of specimens from Mount Gumitir, providing the first comprehensive taxonomic and pharmacological profile to support species authentication and future bioprospecting. The L. condylobulbon specimen displays diagnostic epiphytic morpho-logy, including fusiform pseudobulbs, two elongate leaves, and an erect inflorescence bearing ~123 flowers. Molecular barcoding using matK, rbcL, and ITS2 confirmed its identity, with phylogenetic analyses consistently clustering it with …

Automated Abdominal Aortic Calcification And Trabecular Bone Score Independently Predict Incident Fracture During Routine Osteoporosis Screening, Abadi K. Gebre, Marc Sim, Syed Zulqarnain Gilani, Afsah Saleem, Cassandra Smith, Didier Hans, Siobhan Reid, Barret A. Monchka, Douglas Kimelman, Mohammad Jafari Jozani, John T. Schousboe, Joshua R. Lewis, William D. Leslie, Joshua R. Lewis

Research outputs 2022 to 2026

Abdominal aortic calcification (AAC), a marker of subclinical cardiovascular disease, has previously shown to be associated with low BMD and fracture. However, it remains unclear whether AAC is associated with trabecular bone score (TBS), a gray-level textural measure, or whether it predicts fracture risk independent of this measure. Here, we examined the cross-sectional association of AAC scored using a validated machine learning algorithm (ML-AAC24) with TBS, and their simultaneous associations with incident fractures in 7691 individuals (93.4% women) through the Manitoba BMD Registry (mean age 75.3 yr). The association between ML-AAC24 and TBS was tested using generalized linear regression. Cox …

The Critical Window: How The Design And Implementation Of The Equity To Prosperity Preschool (E2p) Program Shaped Early Childhood Development, Eric D. Harris

Electronic Theses and Dissertations Archive

The Equity to Prosperity (E2P) Preschool Program was designed as an integrated early-childhood intervention that combines structured, developmentally informed instruction with family economic supports to improve the kindergarten readiness of 2-year-old children in Memphis, Tennessee. This study investigated whether the key design and implementation features of the E2P program contribute to its effectiveness and whether these features can inform revisions to early childhood education policy. Using a design-focused case study approach, the analysis drew upon Barzelay’s (2019) mechanism-intent analysis framework to examine how conceptual and embodiment design choices shaped implementation, instructional practice, and child outcomes. For the child cohort represented …

Aldo Faldi's 12 Brevi Studi Seriali And The Modern Solo Oboe Tradition, Michael Isaac Ripple

Electronic Theses and Dissertations Archive

This dissertation examines the pedagogical and musical significance of Aldo Faldi’s 12 Brevi Studi Seriali per Oboe within the broader context of twentieth- and twenty-first-century solo oboe repertoire. While etude literature has historically functioned as a bridge between technical study and performance practice, the standard oboe etude canon remains largely rooted in nineteenth-century tonal idioms and does not adequately address the technical and perceptual demands of post-tonal music. Through detailed analytical study and comparative repertoire analysis, this project argues that Faldi’s etudes provide a systematic pedagogical framework for developing the skills required in contemporary oboe performance. These studies isolate and …

"Finding Greatness Elsewhere": Racial Discrimination And The Attrition Of Black Women In School Psychology Training Programs, Asya Tiani Miles

Electronic Theses and Dissertations Archive

Prior literature identifies discriminatory school experiences as a factor in Black women’s thoughts of leaving school psychology training programs (Jackson, 2023; Proctor, 2009). However, no studies have thoroughly examined how intersecting racial and gender discrimination contributes to Black women’s decisions to follow through with leaving. In addressing this gap, participants included eight Black women who left their programs between 2017 and 2023 due to discriminatory treatment. A reflexive thematic qualitative design was employed, and the following themes emerged: microaggressions, harsher evaluation and academic underestimation, alienation and exclusion, unsuccessful attempts to make the environment more bearable, and finding greatness elsewhere. Implications …

“At That Point You Aren’T Even A Teacher”: Literacy Teacher Resistance In The Age Of The Edtech Panopticon, Dallas Joseph Allen

Electronic Theses and Dissertations Archive

The growth of digital education programs in public education, combined with increased legislative restrictions, has created an environment where literacy and English Language Arts teachers are working under complex networks of surveillance and control, where curriculum materials are provided to them by outside designers. Teachers who have ideological or moral issue with the supplied materials may choose to resist and subvert. Previous research in teacher resistance highlights instructional strategies educators used in the pre-and-early digital era: class discussion, subversive reading, and leveraging institutional authority and experience. This dissertation analyzes qualitative interview data gathered from four high school English Language Arts …

Driving Behavior; Predicting Role Of Social Intelligence And Personal And Social Responsibility, Seyedehsareh Hashemikamangar

Electronic Theses and Dissertations Archive

The goal of this study is to investigate the effects of responsibility and social intelligence on dangerous driving behavior among young drivers. Quantitative (i.e., multiple hierarchical regression) and qualitative (i.e., thematic analysis) methods are combined to achieve this goal. A total of 404 US drivers aged 18-35 participated in this study and completed an online survey that included demographic questions, the Dula Dangerous Driving Index (DDDI), Tromsø Social Intelligence Scale (TSIS), Responsibility Questionnaire (RQ), and open-ended questions. The quantitative results indicated that higher social awareness, social skill, personal responsibility, and social responsibility are correlated with less frequent dangerous driving behavior …

Mental Health In Rural School-Age Youth: Examining Trends In Adverse Childhood Experiences, Positive Childhood Experiences, And Family Resilience From 2018-2023, Mary Katherine Shires

Brown School Graduate Student Theses and Dissertations

This study examined trends in adverse childhood experiences (ACEs), positive childhood experiences (PCEs), family resilience, and mental health conditions in rural and urban youth in the United States from 2018-2023. It also assessed whether PCEs and family resilience moderated the association between ACEs and youth mental health and whether these relationships differed by geographic setting and across time. Data were drawn from six years (2018-2023) of the National Survey of Children’s Health (NSCH), a nationally representative, cross-sectional, caregiver-reported survey assessing child wellbeing. The analytic sample included school-age youth (ages 6-17) residing in states that reported metropolitan (urban) versus non-metropolitan (rural) …