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Articles 288271 - 288300 of 2917251
Full-Text Articles in Entire DC Network
A Grounded Theory Of Enterprising Mothers: Work-Life Balancing Of Women In Fiji, Candauda Arachchige Saliya
A Grounded Theory Of Enterprising Mothers: Work-Life Balancing Of Women In Fiji, Candauda Arachchige Saliya
The Qualitative Report
Gender equality is recognized as crucial for firms’ growth. This paper attempts to investigate how and why do certain sociocultural and structural factors influence sustained gender inequality in Fiji? And then, using Grounded Theory (GT) method, it attempts to conceptualise how are Fijian working mothers striving to promote equality and diversity in the workplace, society, and family-life? By employing Grounded theory (GT) method, semi-structured interviews (32) were used to collect data from high-ranked officers in private and public sectors and, the interview transcripts were analysed using GT techniques: iterative and recursive processes of coding, categorising, theoretical sampling and constant comparison. …
Thank You, Tony E. Adams, Stacy Holman Jones, And Carolyn Ellis, For Offering The Handbook Of Autoethnography, Niroj Dahal
Thank You, Tony E. Adams, Stacy Holman Jones, And Carolyn Ellis, For Offering The Handbook Of Autoethnography, Niroj Dahal
The Qualitative Report
I offer this review on autoethnography for various social science disciplines for readers, writers, and novice and experienced researchers. The second edition of the Handbook of Autoethnography, edited by Tony E. Adams, Stacy Holman Jones, and Carolyn Ellis (2022b), includes contributions from more than 50 authors representing more than a dozen disciplines and writing from different parts of the world and published on year 2022. The book attempted to develop, enhance, and broaden qualitative research and autoethnographic inquiry. This review is based on the section on Doing Autoethnography, which provides examples of diverse, considerate, practical, innovative, and applied …
Reintegration Of Return Migrants In Northern Ghana And Their Remigration Decisions: A Qualitative Study, Benzies Isaac Adu-Okoree Rev. Dr., Daniella Delali Sedegah Dr., Philippa Jilly Joel Premkumar Dr., Prize Fourthson Mcapreko Dr.
Reintegration Of Return Migrants In Northern Ghana And Their Remigration Decisions: A Qualitative Study, Benzies Isaac Adu-Okoree Rev. Dr., Daniella Delali Sedegah Dr., Philippa Jilly Joel Premkumar Dr., Prize Fourthson Mcapreko Dr.
The Qualitative Report
A political discussion has recently erupted over the return of migrant kayayei (head porters) from Northern Ghana. Return migrants were studied meagrely with regard to their reintegration process, skills acquired at their destinations, and chances for productive engagement. These chances allow the return migrants to pursue socially desirable goals. This study attempts to answer the questions pertaining to why migrants remain at home in terms of their experiences in the reintegration process and the reasons for re-migration. The purpose of this study was to explore how the socioeconomic environment of home communities aids the reintegration of return migrants from Ghana's …
Association Of Circulating Markers With Cognitive Decline After Radiation Therapy For Brain Metastasis, Kristin Huntoon, S Keith Anderson, Karla V Ballman, Erin Twohy, Katharine Dooley, Wen Jiang, Yi An, Jing Li, Christina Von Roemeling, Yaqing Qie, Owen A Ross, Jane H Cerhan, Anthony C Whitton, Jeffrey N Greenspoon, Ian F Parney, Jonathan B Ashman, Jean-Paul Bahary, Constantinos Hadjipanayis, James J Urbanic, Elana Farace, Deepak Khuntia, Nadia N Laack, Paul D Brown, David Roberge, Betty Y S Kim
Association Of Circulating Markers With Cognitive Decline After Radiation Therapy For Brain Metastasis, Kristin Huntoon, S Keith Anderson, Karla V Ballman, Erin Twohy, Katharine Dooley, Wen Jiang, Yi An, Jing Li, Christina Von Roemeling, Yaqing Qie, Owen A Ross, Jane H Cerhan, Anthony C Whitton, Jeffrey N Greenspoon, Ian F Parney, Jonathan B Ashman, Jean-Paul Bahary, Constantinos Hadjipanayis, James J Urbanic, Elana Farace, Deepak Khuntia, Nadia N Laack, Paul D Brown, David Roberge, Betty Y S Kim
Faculty, Staff and Student Publications
BACKGROUND: A recent phase III trial (NCT01372774) comparing use of stereotactic radiosurgery [SRS] versus whole-brain radiation therapy [WBRT] after surgical resection of a single brain metastasis revealed that declines in cognitive function were more common with WBRT than with SRS. A secondary endpoint in that trial, and the primary objective in this secondary analysis, was to identify baseline biomarkers associated with cognitive impairment after either form of radiotherapy for brain metastasis. Here we report our findings on APOE genotype and serum levels of associated proteins and their association with radiation-induced neurocognitive decline.
METHODS: In this retrospective analysis of prospectively collected …
A New Method Using Deep Transfer Learning On Ecg To Predict The Response To Cardiac Resynchronization Therapy, Zhuo He, Hongjin Si, Xinwei Zhang, Qing-Hui Chen, Jiangang Zou, Weihua Zhou
A New Method Using Deep Transfer Learning On Ecg To Predict The Response To Cardiac Resynchronization Therapy, Zhuo He, Hongjin Si, Xinwei Zhang, Qing-Hui Chen, Jiangang Zou, Weihua Zhou
Michigan Tech Publications
Background: Cardiac resynchronization therapy (CRT) has emerged as an effective treatment for heart failure patients with electrical dyssynchrony. However, accurately predicting which patients will respond to CRT remains a challenge. This study explores the application of deep transfer learning techniques to train a predictive model for CRT response. Methods: In this study, the short-time Fourier transform (STFT) technique was employed to transform ECG signals into two-dimensional images. A transfer learning approach was then applied on the MIT-BIT ECG database to pre-train a convolutional neural network (CNN) model. The model was fine-tuned to extract relevant features from the ECG images, and …
Crossing Boundaries: Autoethnography Of Subjective Experiences During Meditation, Anna-Katharina Kothe, Stefanie Vochatzer, Christian Oesterle, Steffen Philipp Ruf
Crossing Boundaries: Autoethnography Of Subjective Experiences During Meditation, Anna-Katharina Kothe, Stefanie Vochatzer, Christian Oesterle, Steffen Philipp Ruf
The Qualitative Report
In this autoethnographic quadrologue, the authors aim to show how meditation experiences defy verbalization in a qualitative research setting. This leads to the insight that an autoethnographic approach may be a much better fit for such an experience, where complex and inexpressible things can be found. This is especially the case since autoethnographic texts include and immerse the reader in the experience. Even though in the case of meditation this can hardly be achieved, this quadrologue aims at conveying some of the struggles and peculiarities of meditation practice. It focuses on the research process leading to the decision to employ …
Evaluating The Use Of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, Matthew O Goodman, Alyna T Khan, Jiongming Wang, Elena Feofanova, Joshua C Bis, Kerri L Wiggins, Jennifer E Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L Kinney, Jennifer A Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, Joann E Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C Charles Gu, Donald M Lloyd-Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M Psaty, Donna K Arnett, Carmen R Isasi, Stephen S Rich, Robert C Kaplan, Susan Redline, Braxton D Mitchell, Nora Franceschini, Daniel Levy, Jerome I Rotter, Alanna C Morrison, Tamar Sofer
Evaluating The Use Of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, Matthew O Goodman, Alyna T Khan, Jiongming Wang, Elena Feofanova, Joshua C Bis, Kerri L Wiggins, Jennifer E Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L Kinney, Jennifer A Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, Joann E Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C Charles Gu, Donald M Lloyd-Jones, Sebastian Zöllner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M Psaty, Donna K Arnett, Carmen R Isasi, Stephen S Rich, Robert C Kaplan, Susan Redline, Braxton D Mitchell, Nora Franceschini, Daniel Levy, Jerome I Rotter, Alanna C Morrison, Tamar Sofer
Faculty, Staff and Student Publications
We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population groups. We compare "clumping-and-thresholding" (PRSice2) and LD-based (LDPred2) methods to construct PRSs from each of multiple GWAS, as well as multi-PRS approaches that sum PRSs with and without weights, including PRS-CSx. We use datasets from the MGB Biobank, TOPMed study, UK biobank, and from All of Us to train, assess, and validate PRSs in groups defined by self-reported race/ethnic background (Asian, Black, Hispanic/Latino, and White). For both SBP and DBP, the PRS-CSx based PRS, constructed as a weighted sum of PRSs …
Influence Of Maternal Bmi On Offspring Bmi From In-Utero To Adolescence And Offspring Bmi Trajectories Via Epigenetic Changes, Vimala Devi Janjanam
Influence Of Maternal Bmi On Offspring Bmi From In-Utero To Adolescence And Offspring Bmi Trajectories Via Epigenetic Changes, Vimala Devi Janjanam
Electronic Theses and Dissertations Archive
The impact of maternal body mass index (BMI) on offspring health outcomes such as obesity has been widely investigated, with evidence suggesting that in-utero conditions may influence DNA methylation (DNAm) and BMI developmental trajectories. However, it is unclear whether differential DNAm on sites with a cytosine followed by a guanine linked by phosphate dinucleotide (CpG) related to gestational BMI are linked to BMI changes in offspring. Using data from the Isle of Wight birth cohort, UK, this study aims to investigate BMI trajectories and address the role of DNAm. Using trajectory analysis four distinct BMI developmental trajectories - ‘normal’ (n= …
Editorial: Ijap’S Decade Of Downloads, K.C. O'Rourke, Roisin Donnelly, Claire Mcavinia
Editorial: Ijap’S Decade Of Downloads, K.C. O'Rourke, Roisin Donnelly, Claire Mcavinia
Irish Journal of Academic Practice
No abstract provided.
Habitual Exercise Evokes Fast And Persistent Adaptation During Split-Belt Walking, Sasha A. Brinkerhoff, Natalia Sánchez, Jaimie A. Roper
Habitual Exercise Evokes Fast And Persistent Adaptation During Split-Belt Walking, Sasha A. Brinkerhoff, Natalia Sánchez, Jaimie A. Roper
Physical Therapy Faculty Articles and Research
Changing movement patterns in response to environmental perturbations is a critical aspect of gait and is related to reducing the energetic cost of the movement. Exercise improves energetic capacity for submaximal exercise and may affect how people adapt movement to reach an energetic minimum. The purpose of this study was to determine whether self-reported exercise behavior influences gait adaptation in young adults. Young adults who met the optimal volume of exercise according to the Physical Activity Guidelines for Americans (MOVE; n = 19) and young adults who did not meet the optimal volume of exercise (notMOVE; n = 13) walked …
Evaluation Of Feasibility And Acceptability Of A Web-Based Diabetes Prevention Program (Dpp) For Diabetes Risk Reduction In Chinese Americans In New York City, Ming-Chin Yeh, Wincy Lau, Claire Anselmo Keady, Margrethe Horlyck-Romanovsky, Ho-Jui Tung, Lu Hu, Grace X. Ma, Judith Wylie-Rosett
Evaluation Of Feasibility And Acceptability Of A Web-Based Diabetes Prevention Program (Dpp) For Diabetes Risk Reduction In Chinese Americans In New York City, Ming-Chin Yeh, Wincy Lau, Claire Anselmo Keady, Margrethe Horlyck-Romanovsky, Ho-Jui Tung, Lu Hu, Grace X. Ma, Judith Wylie-Rosett
Health Policy & Community Health: Faculty Publications
Introduction: Intensive lifestyle intervention remains an effective modality to reduce diabetes incidence and delay the progression to type 2 diabetes. The primary aim of this study was to pilot-test the feasibility and acceptability of a culturally and linguistically tailored web-based DPP intervention among Chinese Americans with prediabetes living in New York City.
Methods: Thirteen Chinese American participants with prediabetes were recruited to complete a 1-year web-based Diabetes Prevention Program (DPP) lifestyle intervention. Quantitative and qualitative measures such as retention rate and data collected from web-based questionnaires and focus groups were collected and analyzed to assess study feasibility and …
A Policy Proposal For Agricultural Data Governance, Ana Sofía Castellanos Santamaría
A Policy Proposal For Agricultural Data Governance, Ana Sofía Castellanos Santamaría
Dissertations and Theses
As the digital economy continues to grow and data becomes increasingly important, effective data governance is essential. A data governance framework enables the efficient management, sharing, and integration of data, resulting in better decision-making, increased productivity, and enhanced innovation across industries, including agriculture. However, the agricultural sector in the United States is lagging behind other industries in the adoption of effective data governance practices. Agricultural data governance presents a unique set of challenges due to the wide range of stakeholders involved and the ever-increasing volume of data generated by digital technologies in farming. One key challenge to achieving the benefits …
The Landscape Of Tolerated Genetic Variation In Humans And Primates, Hong Gao, Tobias Hamp, Jeffrey Ede, Joshua G Schraiber, Jeremy Mcrae, Moriel Singer-Berk, Yanshen Yang, Anastasia S D Dietrich, Petko P Fiziev, Lukas F K Kuderna, Laksshman Sundaram, Yibing Wu, Aashish Adhikari, Yair Field, Chen Chen, Serafim Batzoglou, Francois Aguet, Gabrielle Lemire, Rebecca Reimers, Daniel Balick, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien De Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Fabiano R De Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi Do Amaral, Mariluce Messias, Maria N F Da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Thomas Bataillon, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M D Beck, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Monkol Lek, Shamil Sunyaev, Anne O'Donnell-Luria, Heidi L Rehm, Jinbo Xu, Jeffrey Rogers, Tomas Marques-Bonet, Kyle Kai-How Farh
The Landscape Of Tolerated Genetic Variation In Humans And Primates, Hong Gao, Tobias Hamp, Jeffrey Ede, Joshua G Schraiber, Jeremy Mcrae, Moriel Singer-Berk, Yanshen Yang, Anastasia S D Dietrich, Petko P Fiziev, Lukas F K Kuderna, Laksshman Sundaram, Yibing Wu, Aashish Adhikari, Yair Field, Chen Chen, Serafim Batzoglou, Francois Aguet, Gabrielle Lemire, Rebecca Reimers, Daniel Balick, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien De Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idriss S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Fabiano R De Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi Do Amaral, Mariluce Messias, Maria N F Da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Thomas Bataillon, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M D Beck, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Monkol Lek, Shamil Sunyaev, Anne O'Donnell-Luria, Heidi L Rehm, Jinbo Xu, Jeffrey Rogers, Tomas Marques-Bonet, Kyle Kai-How Farh
Faculty, Staff and Students Publications
INTRODUCTION:
Millions of people have received genome and exome sequencing to date, a collective effort that has illuminated for the first time the vast catalog of small genetic differences that distinguish us as individuals within our species. However, the effects of most of these genetic variants remain unknown, limiting their clinical utility and actionability. New approaches that can accurately discern disease-causing from benign mutations and interpret genetic variants on a genome-wide scale would constitute a meaningful initial step towards realizing the potential of personalized genomic medicine.
RATIONALE:
As a result of the short evolutionary distance between humans and nonhuman primates, …
2023-06-02, Board Of Regents, Murray State University
2023-06-02, Board Of Regents, Murray State University
Board of Regents Meeting Minutes
No abstract provided.
A Global Catalog Of Whole-Genome Diversity From 233 Primate Species\, Lukas F K Kuderna, Hong Gao, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien De Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idrissa S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G Schraiber, Fabiano R De Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi, Malu Messias, Maria N F Da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda D Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M D Beck, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Jeffrey Rogers, Kyle Kai-How Farh, Tomas Marques Bonet
A Global Catalog Of Whole-Genome Diversity From 233 Primate Species\, Lukas F K Kuderna, Hong Gao, Mareike C Janiak, Martin Kuhlwilm, Joseph D Orkin, Thomas Bataillon, Shivakumara Manu, Alejandro Valenzuela, Juraj Bergman, Marjolaine Rousselle, Felipe Ennes Silva, Lidia Agueda, Julie Blanc, Marta Gut, Dorien De Vries, Ian Goodhead, R Alan Harris, Muthuswamy Raveendran, Axel Jensen, Idrissa S Chuma, Julie E Horvath, Christina Hvilsom, David Juan, Peter Frandsen, Joshua G Schraiber, Fabiano R De Melo, Fabrício Bertuol, Hazel Byrne, Iracilda Sampaio, Izeni Farias, João Valsecchi, Malu Messias, Maria N F Da Silva, Mihir Trivedi, Rogerio Rossi, Tomas Hrbek, Nicole Andriaholinirina, Clément J Rabarivola, Alphonse Zaramody, Clifford J Jolly, Jane Phillips-Conroy, Gregory Wilkerson, Christian Abee, Joe H Simmons, Eduardo Fernandez-Duque, Sree Kanthaswamy, Fekadu Shiferaw, Dongdong Wu, Long Zhou, Yong Shao, Guojie Zhang, Julius D Keyyu, Sascha Knauf, Minh D Le, Esther Lizano, Stefan Merker, Arcadi Navarro, Tilo Nadler, Chiea Chuen Khor, Jessica Lee, Patrick Tan, Weng Khong Lim, Andrew C Kitchener, Dietmar Zinner, Ivo Gut, Amanda D Melin, Katerina Guschanski, Mikkel Heide Schierup, Robin M D Beck, Govindhaswamy Umapathy, Christian Roos, Jean P Boubli, Jeffrey Rogers, Kyle Kai-How Farh, Tomas Marques Bonet
Faculty, Staff and Students Publications
The rich diversity of morphology and behavior displayed across primate species provides an informative context in which to study the impact of genomic diversity on fundamental biological processes. Analysis of that diversity provides insight into long-standing questions in evolutionary and conservation biology and is urgent given severe threats these species are facing. Here, we present high-coverage whole-genome data from 233 primate species representing 86% of genera and all 16 families. This dataset was used, together with fossil calibration, to create a nuclear DNA phylogeny and to reassess evolutionary divergence times among primate clades. We found within-species genetic diversity across families …
Phylogenomic Analyses Provide Insights Into Primate Evolution, Yong Shao, Long Zhou, Fang Li, Lan Zhao, Bao-Lin Zhang, Feng Shao, Jia-Wei Chen, Chun-Yan Chen, Xupeng Bi, Xiao-Lin Zhuang, Hong-Liang Zhu, Jiang Hu, Zongyi Sun, Xin Li, Depeng Wang, Iker Rivas-González, Sheng Wang, Yun-Mei Wang, Wu Chen, Gang Li, Hui-Meng Lu, Yang Liu, Lukas F K Kuderna, Kyle Kai-How Farh, Peng-Fei Fan, Li Yu, Ming Li, Zhi-Jin Liu, George P Tiley, Anne D Yoder, Christian Roos, Takashi Hayakawa, Tomas Marques-Bonet, Jeffrey Rogers, Peter D Stenson, David N Cooper, Mikkel Heide Schierup, Yong-Gang Yao, Ya-Ping Zhang, Wen Wang, Xiao-Guang Qi, Guojie Zhang, Dong-Dong Wu
Phylogenomic Analyses Provide Insights Into Primate Evolution, Yong Shao, Long Zhou, Fang Li, Lan Zhao, Bao-Lin Zhang, Feng Shao, Jia-Wei Chen, Chun-Yan Chen, Xupeng Bi, Xiao-Lin Zhuang, Hong-Liang Zhu, Jiang Hu, Zongyi Sun, Xin Li, Depeng Wang, Iker Rivas-González, Sheng Wang, Yun-Mei Wang, Wu Chen, Gang Li, Hui-Meng Lu, Yang Liu, Lukas F K Kuderna, Kyle Kai-How Farh, Peng-Fei Fan, Li Yu, Ming Li, Zhi-Jin Liu, George P Tiley, Anne D Yoder, Christian Roos, Takashi Hayakawa, Tomas Marques-Bonet, Jeffrey Rogers, Peter D Stenson, David N Cooper, Mikkel Heide Schierup, Yong-Gang Yao, Ya-Ping Zhang, Wen Wang, Xiao-Guang Qi, Guojie Zhang, Dong-Dong Wu
Faculty, Staff and Students Publications
Comparative analysis of primate genomes within a phylogenetic context is essential for understanding the evolution of human genetic architecture and primate diversity. We present such a study of 50 primate species spanning 38 genera and 14 families, including 27 genomes first reported here, with many from previously less well represented groups, the New World monkeys and the Strepsirrhini. Our analyses reveal heterogeneous rates of genomic rearrangement and gene evolution across primate lineages. Thousands of genes under positive selection in different lineages play roles in the nervous, skeletal, and digestive systems and may have contributed to primate innovations and adaptations. Our …
Genome-Wide Coancestry Reveals Details Of Ancient And Recent Male-Driven Reticulation In Baboons, Erik F Sørensen, R Alan Harris, Liye Zhang, Muthuswamy Raveendran, Lukas F K Kuderna, Jerilyn A Walker, Jessica M Storer, Martin Kuhlwilm, Claudia Fontsere, Lakshmi Seshadri, Christina M Bergey, Andrew S Burrell, Juraj Bergman, Jane E Phillips-Conroy, Fekadu Shiferaw, Kenneth L Chiou, Idrissa S Chuma, Julius D Keyyu, Julia Fischer, Marie-Claude Gingras, Sejal Salvi, Harshavardhan Doddapaneni, Mikkel H Schierup, Mark A Batzer, Clifford J Jolly, Sascha Knauf, Dietmar Zinner, Kyle K-H Farh, Tomas Marques-Bonet, Kasper Munch, Christian Roos, Jeffrey Rogers
Genome-Wide Coancestry Reveals Details Of Ancient And Recent Male-Driven Reticulation In Baboons, Erik F Sørensen, R Alan Harris, Liye Zhang, Muthuswamy Raveendran, Lukas F K Kuderna, Jerilyn A Walker, Jessica M Storer, Martin Kuhlwilm, Claudia Fontsere, Lakshmi Seshadri, Christina M Bergey, Andrew S Burrell, Juraj Bergman, Jane E Phillips-Conroy, Fekadu Shiferaw, Kenneth L Chiou, Idrissa S Chuma, Julius D Keyyu, Julia Fischer, Marie-Claude Gingras, Sejal Salvi, Harshavardhan Doddapaneni, Mikkel H Schierup, Mark A Batzer, Clifford J Jolly, Sascha Knauf, Dietmar Zinner, Kyle K-H Farh, Tomas Marques-Bonet, Kasper Munch, Christian Roos, Jeffrey Rogers
Faculty, Staff and Students Publications
Baboons (genus Papio) are a morphologically and behaviorally diverse clade of catarrhine monkeys that have experienced hybridization between phenotypically and genetically distinct phylogenetic species. We used high-coverage whole-genome sequences from 225 wild baboons representing 19 geographic localities to investigate population genomics and interspecies gene flow. Our analyses provide an expanded picture of evolutionary reticulation among species and reveal patterns of population structure within and among species, including differential admixture among conspecific populations. We describe the first example of a baboon population with a genetic composition that is derived from three distinct lineages. The results reveal processes, both ancient and …
Evaluating The Use Of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, C Charles Gu, Et Al.
Evaluating The Use Of Blood Pressure Polygenic Risk Scores Across Race/Ethnic Background Groups, Nuzulul Kurniansyah, C Charles Gu, Et Al.
2020-Current year OA Pubs
We assess performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure (BP) phenotypes in diverse population groups. We compare "clumping-and-thresholding" (PRSice2) and LD-based (LDPred2) methods to construct PRSs from each of multiple GWAS, as well as multi-PRS approaches that sum PRSs with and without weights, including PRS-CSx. We use datasets from the MGB Biobank, TOPMed study, UK biobank, and from All of Us to train, assess, and validate PRSs in groups defined by self-reported race/ethnic background (Asian, Black, Hispanic/Latino, and White). For both SBP and DBP, the PRS-CSx based PRS, constructed as a weighted sum of PRSs …
Investigating Eco-Evolutionary Interactions Between Hosts And Members Of Their Gut Microbiota, Logan A. Sauers
Investigating Eco-Evolutionary Interactions Between Hosts And Members Of Their Gut Microbiota, Logan A. Sauers
Theses and Dissertations
Evolutionary and ecological interactions between hosts and their associated microbial communities, their microbiota, and between members of these communities are vital to understand. Microbial communities are widespread across diverse host taxa and hosts receive a variety of well-documented benefits from their microbial communities. Despite the importance of understanding eco-evolutionary dynamics for colonization outcomes and the benefits these communities provide to their hosts, our current knowledge in this area remains incomplete. For example, we do not know the full extent of coevolution and specific relationships between hosts and microbes, and between the microbes themselves, across host taxa. Questions remain about how …
Transition Planning And The School To Prison Pipeline: A Phenomenological Study Investigating The Lived Experiences Of Alternatively Placed High School Black Males With High Incidence Disabilities, Brandon Garrett Thornton
Transition Planning And The School To Prison Pipeline: A Phenomenological Study Investigating The Lived Experiences Of Alternatively Placed High School Black Males With High Incidence Disabilities, Brandon Garrett Thornton
Theses and Dissertations
The purpose of this qualitative study was to better inform researchers and practitioners on best practices to ensure that their transition planning practices are person-centered and culturally responsive. Using a phenomenological approach, purposeful sampling was used to conduct semi-structured interviews regarding the shared educational lived experiences of two alternatively placed Black high school males with high incidence disabilities with respect to their transition planning. Participants perceived their transition planning to be student-centered, and expected favorable employment outcomes. Additionally, the participants’ choice to be alternatively placed played a role in their perception of transition outcomes. School personnel also played a pivotal …
Knowledge Management Practice And Use Of Information And Communication Technology: A Case Study Of Northwest University, Kano, Karimatu Isa Maisango Dr, Farida Sani Stores Dr
Knowledge Management Practice And Use Of Information And Communication Technology: A Case Study Of Northwest University, Kano, Karimatu Isa Maisango Dr, Farida Sani Stores Dr
Library Philosophy and Practice (e-journal)
Knowledge management has become a key factor for the success of all organizations. Information and communication technology (ICT) remains the only technology that facilitates information and knowledge sharing in any organization. Therefore, its use is prominent in any form of knowledge management initiative. The value of knowledge management is more when made available to the right people at the right time. Thus, knowledge sharing is facilitated through information and communication technology including computers, telephones, e-mail, databases, data mining systems, search engines, video conference and many more. The chapter investigates the practice of knowledge capture, sharing, storage and utilization among the …
Combinatorial Bcl2 Family Expression In Acute Myeloid Leukemia Stem Cells Predicts Clinical Response To Azacitidine/Venetoclax, Alexander Waclawiczek, Darja Karpova, Et Al.
Combinatorial Bcl2 Family Expression In Acute Myeloid Leukemia Stem Cells Predicts Clinical Response To Azacitidine/Venetoclax, Alexander Waclawiczek, Darja Karpova, Et Al.
2020-Current year OA Pubs
UNLABELLED: The BCL2 inhibitor venetoclax (VEN) in combination with azacitidine (5-AZA) is currently transforming acute myeloid leukemia (AML) therapy. However, there is a lack of clinically relevant biomarkers that predict response to 5-AZA/VEN. Here, we integrated transcriptomic, proteomic, functional, and clinical data to identify predictors of 5-AZA/VEN response. Although cultured monocytic AML cells displayed upfront resistance, monocytic differentiation was not clinically predictive in our patient cohort. We identified leukemic stem cells (LSC) as primary targets of 5-AZA/VEN whose elimination determined the therapy outcome. LSCs of 5-AZA/VEN-refractory patients displayed perturbed apoptotic dependencies. We developed and validated a flow cytometry-based "Mediators of …
Altered Signaling And Desensitization Responses In Pth1r Mutants Associated With Eiken Syndrome, Ignacio Portales-Castillo, Thomas Dean, Ross W Cheloha, Brendan A Creemer, Jean-Pierre Vilardaga, Sofya Savransky, Ashok Khatri, Harald Jüppner, Thomas J Gardella
Altered Signaling And Desensitization Responses In Pth1r Mutants Associated With Eiken Syndrome, Ignacio Portales-Castillo, Thomas Dean, Ross W Cheloha, Brendan A Creemer, Jean-Pierre Vilardaga, Sofya Savransky, Ashok Khatri, Harald Jüppner, Thomas J Gardella
2020-Current year OA Pubs
The parathyroid hormone receptor type 1 (PTH1R) is a G protein-coupled receptor that plays key roles in regulating calcium homeostasis and skeletal development via binding the ligands, PTH and PTH-related protein (PTHrP), respectively. Eiken syndrome is a rare disease of delayed bone mineralization caused by homozygous PTH1R mutations. Of the three mutations identified so far, R485X, truncates the PTH1R C-terminal tail, while E35K and Y134S alter residues in the receptor's amino-terminal extracellular domain. Here, using a variety of cell-based assays, we show that R485X increases the receptor's basal rate of cAMP signaling and decreases its capacity to recruit β-arrestin2 upon …
Wave-By-Wave Forecasts In Directional Seas Using Nonlinear Dispersion Corrections, Eytan Meisner, Mariano Galvagno, David Andrade, Dan Liberzon, Raphael Stuhlmeier
Wave-By-Wave Forecasts In Directional Seas Using Nonlinear Dispersion Corrections, Eytan Meisner, Mariano Galvagno, David Andrade, Dan Liberzon, Raphael Stuhlmeier
School of Engineering, Computing and Mathematics
We develop a new methodology for the deterministic forecasting of directional ocean surface waves based on nonlinear frequency corrections. These frequency corrections can be pre-computed based on measured energy density spectra and, therefore, come at no additional computational cost compared to linear theory. The nonlinear forecasting methodology is tested on highly nonlinear synthetically generated seas with a variety of values of average steepness and directional spreading and is shown to consistently outperform a linear forecast.
Modeling The Longitudinal Changes Of Ancestry Diversity In The Million Veteran Program, Frank R Wendt, Gita A Pathak, Jacqueline Vahey, Xuejun Qin, Dora Koller, Brenda Cabrera-Mendoza, Angela Haeny, Kelly M Harrington, Nallakkandi Rajeevan, Linh M Duong, Daniel F Levey, Flavio De Angelis, Antonella De Lillo, Tim B Bigdeli, Saiju Pyarajan, John Michael Gaziano, Joel Gelernter, Mihaela Aslan, Dawn Provenzale, Drew A Helmer, Elizabeth R Hauser, Renato Polimanti, Department Of Veteran Affairs Cooperative Study Program (#2006)
Modeling The Longitudinal Changes Of Ancestry Diversity In The Million Veteran Program, Frank R Wendt, Gita A Pathak, Jacqueline Vahey, Xuejun Qin, Dora Koller, Brenda Cabrera-Mendoza, Angela Haeny, Kelly M Harrington, Nallakkandi Rajeevan, Linh M Duong, Daniel F Levey, Flavio De Angelis, Antonella De Lillo, Tim B Bigdeli, Saiju Pyarajan, John Michael Gaziano, Joel Gelernter, Mihaela Aslan, Dawn Provenzale, Drew A Helmer, Elizabeth R Hauser, Renato Polimanti, Department Of Veteran Affairs Cooperative Study Program (#2006)
Center for Medical Ethics and Health Policy Staff Publications
Background: The Million Veteran Program (MVP) participants represent 100 years of US history, including significant social and demographic changes over time. Our study assessed two aspects of the MVP: (i) longitudinal changes in population diversity and (ii) how these changes can be accounted for in genome-wide association studies (GWAS). To investigate these aspects, we divided MVP participants into five birth cohorts (N-range = 123,888 [born from 1943 to 1947] to 136,699 [born from 1948 to 1953]).
Results: Ancestry groups were defined by (i) HARE (harmonized ancestry and race/ethnicity) and (ii) a random-forest clustering approach using the 1000 Genomes Project and …
A Gender Perspective Analysis Of Chinese Nationals’ Leisure Time Allocation: Family Life Cycle Versus Demographic Determinants, Jiaqi Luo, Songshan Huang, Ronghui Jiao, Zhiyong Li
A Gender Perspective Analysis Of Chinese Nationals’ Leisure Time Allocation: Family Life Cycle Versus Demographic Determinants, Jiaqi Luo, Songshan Huang, Ronghui Jiao, Zhiyong Li
Research outputs 2022 to 2026
Family life cycle and gender have a great impact on people’s leisure time allocation. This study uses a nationwide survey to examine the influence of family life cycle and demographic characteristics on Chinese nationals’ leisure time allocation from a gender perspective. We found that Chinese nationals in the life stage of “family with infants” have the least leisure time among the study subjects. Men have more leisure time than women at any stage of the life cycle. Marriage has the greatest negative effect on women’s educational leisure (amateur learning, non-formal education, and reading) and men’s physical leisure (physical exercises and …
Ai Art: Artists’ Best Friend Or Mortal Enemy?, Ethan Gabrys
Ai Art: Artists’ Best Friend Or Mortal Enemy?, Ethan Gabrys
Tredway Library Prize for First-Year Research
This paper analyzes the impacts and implications of generative AI software on art and examines the ethics of using such tools. Through the argument that careless use of these tools presents a danger to the art world as they risk devaluing human expression, Gabrys states that “as what it means to be human changes with each generation, new artists express sentiment through their art. Art has the ability to tell us about the human experience.” He concludes that the use of AI tools takes the skill and sentiment of human artists out of the equation, begging the question: if the …
Experiences Of Students In Degree-Seeking Proprietary Nursing Programs In South Florida, Yvanessa Georges
Experiences Of Students In Degree-Seeking Proprietary Nursing Programs In South Florida, Yvanessa Georges
Dissertations
Students of proprietary programs perform significantly lower in the NCLEX than students of other programs. This is more significant in the state of Florida where the NCLEX pass rate is below the national average. Although the discrepancy in the first-time pass rates is well documented in the statistics, the reason for this is unclear, and there is paucity in the literature addressing this phenomenon.
The purpose of this study was to explore the lived experience of nursing students attending degree-seeking proprietary programs in South Florida.
Shared Fantasy: Role-Playing Games As Social Worlds By Gary Alan Fine (2002) [Reseña], Cristo Leon
Shared Fantasy: Role-Playing Games As Social Worlds By Gary Alan Fine (2002) [Reseña], Cristo Leon
Journal of Roleplaying Studies and STEAM
This classic study still provides one of the most acute descriptions available of an often misunderstood subculture: that of fantasy role playing games like Dungeons & Dragons. Gary Alan Fine immerses himself in several different gaming systems, offering insightful details on the nature of the games and the patterns of interaction among players—as well as their reasons for playing.
Este estudio clásico todavía proporciona una de las descripciones más agudas disponibles de una subcultura a menudo incomprendida: la de los juegos de rol de fantasía como Dungeons & Dragons. Gary Alan Fine se sumerge en varios sistemas de juego diferentes …