Digital Commons Network^™

Assessment Of 2019 George R. Farmer Jr. Law Library Strategy Map, Caroline L. Osborne

Law Library Annual Reports and Assessments

No abstract provided.

Antimicrobial Resistance: A Growing Serious Threat For Global Public Health, Md Abdus Salam, Md Yusuf Al-Amin, Moushumi Tabassoom Salam, Jogendra Singh Pawar, Naseem Akhter, Ali A. Rabaan, Mohammed A. A Alqumber

Neurology Articles

Antibiotics are among the most important discoveries of the 20th century, having saved millions of lives from infectious diseases. Microbes have developed acquired antimicrobial resistance (AMR) to many drugs due to high selection pressure from increasing use and misuse of antibiotics over the years. The transmission and acquisition of AMR occur primarily via a human-human interface both within and outside of healthcare facilities. A huge number of interdependent factors related to healthcare and agriculture govern the development of AMR through various drug-resistance mechanisms. The emergence and spread of AMR from the unrestricted use of antimicrobials in livestock feed has been …

July 5 Roundtable Update, Jeffrey M. Wice

Elections, Census & Redistricting Updates

No abstract provided.

California’S Failure To Protect Families: Statutory Reform To Better Serve Families Experiencing Domestic Violence, Cecilia Bobbitt

Loyola of Los Angeles Law Review

Los Angeles County is home to the largest child dependency system in the world. A significant portion of the families involved in this system have experienced domestic violence. Because the system is ineffective in responding to domestic violence, families experiencing domestic violence are especially vulnerable to the harms of the family regulation system. The harm that results is the separation of families, leading to irreparable harm and trauma which hurts, rather than helps, families.

This Article’s findings are based on qualitative legal and social science research, including deidentified data from a 2021 UCLA Pritzker Center for Strengthening Families study regarding …

Allocating Deference In Shared Administrative Space, Juan Caballero

Loyola of Los Angeles Law Review

How do courts allocate deference when multiple agencies propose conflicting interpretations? While the Supreme Court has a clearly established Chevron-Mead paradigm for a single agency engaging in statutory interpretation, it has yet to articulate a method for applying deference in “shared administrative spaces,” legal jurisdictions wherein statutes task multiple agencies with implementing their provisions. The Court’s silence in this arena has allowed lower courts and scholars to develop competing and conflicting approaches to applying deference in shared administrative spaces.

This Article challenges the previously proposed rules for shared administrative spaces and proposes a new one. Courts should reframe Chevron “step …

The (Ir)Relevance Of Positivist Arguments For Originalism, Andrew Jordan

Loyola of Los Angeles Law Review

Some constitutional theorists have started looking to jurisprudential accounts of the nature of law for help in resolving disputes in constitutional theory. Most prominent is the “positive turn” defended by William Baude and Stephen Sachs. According to Baude and Sachs, ongoing debates in constitutional theory can be resolved by looking to positive law—that is, to the convergent social practices of legal officials. As a result, they claim that we can avoid the normative debates that have traditionally occupied constitutional theorists. Here, I argue that any attempt to settle substantive debates in constitutional theory via jurisprudential accounts of the nature of …

Too Close To Home?: The Constitutionality Of California’S S.B. 9, Stefan Ecklund

Loyola of Los Angeles Law Review

In 2022, Senate Bill 9 went into effect in California. This law allows owners of single-family-zoned parcels to split their lots in two and build at most two units on each parcel, regardless of local land use ordinances, but subject to detailed conditions. This law is one recent attempt to encourage housing development in a state where local opposition to denser housing has been blamed for the state’s current housing affordability problem. This Note will discuss S.B. 9 and the test courts apply to determine when a state law infringes too much on a charter city’s control over “municipal affairs” …

John Doe, Appellant / Cross-Appellee, Vs. State Of Utah, Office Of State Debt Collection, Appellee / Cross-Appellant : Brief Of Appellant, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

No abstract provided.

Who's Publishing What: Chicken Soup For The Soul: Well That Was Funny, Erma Bombeck Writers' Workshop

Erma Bombeck Writers' Workshop Blog

After attending the Erma Bombeck Writers’ Workshop, Juliann Wetz-Jones decided to try her hand at humor writing. The result: a piece in Chicken Soup for the Soul: Well THAT Was Funny.

Tissue Mass Spectrometry: How Solid Is Our Future?, Daisy Unsihuay, William S Phipps, Amanda G Paulovich, Jessica R Chapman, Axel Ducret, Livia S Eberlin, Jeffrey M Spraggins, Richard J A Goodwin

Center for Medical Ethics and Health Policy Staff Publications

No abstract provided.

Stare Decisis And The Status Of California’S Super Pension Contract, T. Leigh Anenson, Jennifer K. Gershberg

Loyola of Los Angeles Law Review

A fundamental principle of law is that courts stand by their decisions. Under the principle of stare decisis, judicial action strives for stability and coherence by setting precedents for the future in deciding current cases. This Article presents an original inquiry into the overruling expression and criteria for stare decisis in the public pension reform context of California’s constitutional contract law. While there is a lively debate among commentators and judges about the role of stare decisis theory and doctrine in federal law, our study extends that conversation to state law for the first time. We develop a new decision-making …

Beyond The “Model Minority” Mirage: How Does Positive Bias Affect Asian Students And Other Students Of Color?, Ying Shi, Maria Zhu

Center for Policy Research

Asian Americans are often perceived as a “model minority” in classrooms. While this stereotype seems positive, it may raise expectations for Asian students and bolster negative stereotypes for students in other minority groups due to teacher bias. This brief summarizes findings from a study that used data from the North Carolina Education Research Data Center (NCERDC) from 2007 to 2013 to identify the presence of positive bias in teachers’ assessments towards Asian American students in grades 3-8 and its effects on other minority groups. The authors find that teachers rate Asian students’ academic skills more favorably than similar White students …

Why China Cares About Canada’S Indigenous Residential Schools: From Whataboutism To Internal Denial, Xiyuan (Marvin) Xia

Genocide Studies and Prevention: An International Journal

This article examines how the Chinese government and its propaganda departments use genocide-related discourses to fulfil different political purposes at home and abroad. By criticizing Western colonialist regimes’ assimilation policies, especially Canada’s Indigenous residential schools, the Chinese diplomats apply the rhetoric of whataboutism to dodge the international community’s questions about China’s systematic persecution of Uyghur Muslims. Domestically, China’s state media intensively cover Canada’s residential school system and the colonial genocide against Indigenous people, trying to distract the audience from the state atrocities in Xinjiang and mislead the public to distrust Canada and other countries’ motives for accusing China of committing …

Interpreting “Knowingly” To Establish Criminal Liability In Environmental Law: A Modified Public Welfare Approach, Jesse Harte Edelman

Loyola of Los Angeles Law Review

Now, more than ever, environmental disasters occur on an unprecedented scale. The main objective of environmental law is to protect the environment and human health from harm. In recognition of the role that businesses and corporations play in causing such harm, many environmental laws have been amended to criminalize their harmful conduct.

Focusing on the criminal provisions in the Clean Air Act, Clean Water Act, and Resource Conservation and Recovery Act that target offenders who engage in conduct “knowingly,” this Note addresses the split regarding the intent required for a criminal conviction, and the resultant weight accorded these statutes. Courts …

Early Antiretroviral Therapy Not Associated With Higher Cryptococcal Meningitis Mortality In People With Human Immunodeficiency Virus In High-Income Countries: An International Collaborative Cohort Study, Suzanne M Ingle, Elvin Geng, Et Al.

2020-Current year OA Pubs

BACKGROUND: Randomized controlled trials (RCTs) from low- and middle-income settings suggested that early initiation of antiretroviral therapy (ART) leads to higher mortality rates among people with HIV (PWH) who present with cryptococcal meningitis (CM). There is limited information about the impact of ART timing on mortality rates in similar people in high-income settings.

METHODS: Data on ART-naive PWH with CM diagnosed from 1994 to 2012 from Europe/North America were pooled from the COHERE, NA-ACCORD, and CNICS HIV cohort collaborations. Follow-up was considered to span from the date of CM diagnosis to earliest of the following: death, last follow-up, or 6 …

Unexpected Sound Omissions Are Signaled In Human Posterior Superior Temporal Gyrus: An Intracranial Study, Hohyun Cho, Yvonne M Fonken, Markus Adamek, Richard Jimenez, Jack J Lin, Gerwin Schalk, Robert T Knight, Peter Brunner

2020-Current year OA Pubs

Context modulates sensory neural activations enhancing perceptual and behavioral performance and reducing prediction errors. However, the mechanism of when and where these high-level expectations act on sensory processing is unclear. Here, we isolate the effect of expectation absent of any auditory evoked activity by assessing the response to omitted expected sounds. Electrocorticographic signals were recorded directly from subdural electrode grids placed over the superior temporal gyrus (STG). Subjects listened to a predictable sequence of syllables, with some infrequently omitted. We found high-frequency band activity (HFA, 70-170 Hz) in response to omissions, which overlapped with a posterior subset of auditory-active electrodes …

Comparison Of Patient Exit Interviews With Unannounced Standardised Patients For Assessing Hiv Service Delivery In Zambia: A Study Nested Within A Cluster Randomised Trial, Kombatende Sikombe, Aaloke Mody, Ingrid Eshun-Wilson, Elvin Geng, Et Al.

2020-Current year OA Pubs

OBJECTIVES: To compare unannounced standardised patient approach (eg, mystery clients) with typical exit interviews for assessing patient experiences in HIV care (eg, unfriendly providers, long waiting times). We hypothesise standardised patients would report more negative experiences than typical exit interviews affected by social desirability bias.

SETTING: Cross-sectional surveys in 16 government-operated HIV primary care clinics in Lusaka, Zambia providing antiretroviral therapy (ART).

PARTICIPANTS: 3526 participants aged ≥18 years receiving ART participated in the exit surveys between August 2019 and November 2021.

INTERVENTION: Systematic sample (every n

OUTCOME MEASURES: We compared patient experience among patients who received brief training prior to …

An Immunostimulatory Glycolipid That Blocks Sars-Cov-2, Rsv, And Influenza Infections In Vivo, Moriya Tsuji, Zhenlu Chong, Tamarand L Darling, Kuljeet Seehra, Adrianus C M Boon, Michael S Diamond, Et Al.

2020-Current year OA Pubs

Prophylactic vaccines for SARS-CoV-2 have lowered the incidence of severe COVID-19, but emergence of viral variants that are antigenically distinct from the vaccine strains are of concern and additional, broadly acting preventive approaches are desirable. Here, we report on a glycolipid termed 7DW8-5 that exploits the host innate immune system to enable rapid control of viral infections in vivo. This glycolipid binds to CD1d on antigen-presenting cells and thereby stimulates NKT cells to release a cascade of cytokines and chemokines. The intranasal administration of 7DW8-5 prior to virus exposure significantly blocked infection by three different authentic variants of SARS-CoV-2, as …

Rad51 Foci As A Biomarker Predictive Of Platinum Chemotherapy Response In Ovarian Cancer, Amanda J Compadre, Lillian N Van Biljon, Mark C Valentine, Emily Graham, Bisiayo Fashemi, Emilee N Kotnik, Isaac Cooper, Lindsay M Kuroki, Carolyn K Mccourt, Andrea R Hagemann, Premal H Thaker, David G Mutch, Matthew A Powell, Lulu Sun, Nima Mosammaparast, Peinan Zhao, Elena Lomonosova, Dineo Khabele, Mary M Mullen, Et Al.

2020-Current year OA Pubs

PURPOSE: To determine the ability of RAD51 foci to predict platinum chemotherapy response in high-grade serous ovarian cancer (HGSOC) patient-derived samples.

EXPERIMENTAL DESIGN: RAD51 and γH2AX nuclear foci were evaluated by immunofluorescence in HGSOC patient-derived cell lines (n = 5), organoids (n = 11), and formalin-fixed, paraffin-embedded tumor samples (discovery n = 31, validation n = 148). Samples were defined as RAD51-High if >10% of geminin-positive cells had ≥5 RAD51 foci. Associations between RAD51 scores, platinum chemotherapy response, and survival were evaluated.

RESULTS: RAD51 scores correlated with in vitro response to platinum chemotherapy in established and primary ovarian cancer cell …

Law School News: Rwu Alumni Named To Pbn's 2023 40 Under Forty List 7/5/2023, Stacey Pacheco

Life of the Law School (1993- )

No abstract provided.

Yes-Associated Protein-1 Overexpression In Ocular Surface Squamous Neoplasia; A Potential Diagnostic Marker And Therapeutic Target, Peter Julius, Stepfanie N. Siyumbwa, Fred Maate, Phyllis Moonga, Guobin Kang, Trevor Kaile, John T. West, Charles Wood, Peter C. Angeletti

School of Graduate Studies Faculty Publications

Yes-associated protein-1 (YAP-1) is a Hippo system transcription factor, which serves as an oncogene in squamous cell carcinoma, and several solid tumors when the Hippo pathway is dysregulated. Yet, the activity of YAP-1 in ocular surface squamous neoplasia (OSSN) has not been determined. Here, we investigate the relationship between YAP-1 overexpression and OSSN. Using a cross-sectional study design, we recruited 227 OSSN patients from the University Teaching Hospitals in Lusaka, Zambia. Immunohistochemistry was used to assess YAP-1 protein overexpression in tumor tissue relative to surrounding benign squamous epithelium. OSSN patient samples (preinvasive, n = 62, 27% and invasive, n = …

Assessment Of The Immune Response In Patients With Insulin Resistance, Obesity, And Diabetes To Covid-19 Vaccination, Jędrzej Warpechowski, Paula Leszczyńska, Dominika Juchnicka, Adam Olichwier, Łukasz Szczerbiński, Adam Jacek Krętowski

Department of Nutrition and Health Sciences: Faculty Publications

The SARS-CoV-19 pandemic overwhelmed multiple healthcare systems across the world. Patients with underlying medical conditions such as obesity or diabetes were particularly vulnerable, had more severe symptoms, and were more frequently hospitalized. To date, there have been many studies on the severity of SARS-CoV-2 in patients with metabolic disorders, but data on the efficiency of vaccines against COVID-19 are still limited. This paper aims to provide a comprehensive overview of the effectiveness of COVID-19 vaccines in individuals with diabetes, insulin resistance, and obesity. A comparison is made between the immune response after vaccination in patients with and without metabolic comorbidities. …

Exploration Of Shared Passenger Urban Air Mobility – Integrated Network Design, Operation Scheduling And System Configuration, Zhiqiang Wu

USF Tampa Graduate Theses and Dissertations

Urban air mobility (UAM) is an emerging concept proposed in recent years that uses electric vertical take-off and landing vehicles (eVTOLs). UAM is expected to offer an alternative way of transporting passengers and goods in urban areas with significantly improved mobility by making use of low-altitude airspace. Considering the high capital investment of eVTOLs and relative high fee of using UAM passenger service, a viable UAM format is shared passenger service. Such a service is usually station-based, i.e., with vertiport located in popular sites where potential passengers can access. To understand the viability of such use cases, the vertiport owners …

Estimation Of The Kelvin–Helmholtz Unstable Boundary, Xuanye Ma

Publications

The Kelvin–Helmholtz (KH) instability is one of the most important mechanisms of the viscous like interaction between the solar wind and the magnetosphere (MSP), which transport the mass, energy, momentum, and magnetic flux. Thus, it is important to examine whether the magnetopause boundary is KH unstable or not. Based on the KH onset conditions, this report proposes to use a matrix to identify the most KH unstable direction based on the in-situ measurements of the density, velocity, and magnetic field in the MSP and magneto sheath. The range of the KH unstable direction can be easily estimated based on the …

Per Oral Endoscopic Myotomy In Pregnancy, Julie Gomez, Laura Felder, Divya Chalikonda, Alexander Schlachterman, Vincenzo Berghella

Department of Obstetrics and Gynecology Faculty Papers

OBJECTIVE: To report the first successful full-term delivery following Per Oral Endoscopic Myotomy (POEM) performed during pregnancy.

METHODS/BACKGROUND: Achalasia is an esophageal motility disorder characterized by dysphagia, regurgitation, reflux, recurrent vomiting, and weight loss. Achalasia in pregnancy can affect nutritional status of the mother, and subsequently, the child, increasing morbidity and creating potential pregnancy complications. POEM is a novel endoscopic procedure which involves cutting the lower esophageal sphincter to allow food to pass, and is considered a safe and effective management option for achalasia in non-pregnant individuals.

RESULTS: We discuss the case of a patient with achalasia and a prior …

Occupational Therapists’ Perceptions Of Practice During The Covid-19 Pandemic And The Impact On Their Mental Health And Well-Being, Victoria Long

Online Theses and Dissertations

Throughout the COVID-19 pandemic occupational therapists worked through a plethora of stressors. Research concerning the mental health of occupational therapists working in inpatient settings during the COVID-19 pandemic has been underexplored. The purpose of this qualitative descriptive study is to understand the effects of the COVID-19 pandemic on mental health and perceptions of healthcare for occupational therapists working in inpatient settings. Ten occupational therapists, recruited via purposive sampling, completed a semi-structured interview. The transcription was coded using thematic analysis finding five main themes. The five main themes included: fear impacts occupational therapists' performance patterns; workplace barriers influence quality of care; …

Pcos Health-Related Quality-Of-Life And Depressive Symptoms Across The Lifespan: Comparative Study, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Abbas S. Tavakoli, Cynthia F. Corbett Phd, Rn, Faan

Publications

The purpose of this cross-sectional study was to compare health-related quality of life (HRQoL) and depressive symptoms among peri-postmenopausal women with polycystic ovary syndrome (PCOS) aged ≥43 years relative to premenopausal women with PCOS aged 18-42 years. An online survey link comprising questionnaires about demographics, HRQoL, and depressive symptoms was posted onto two PCOS-specific Facebook groups. Respondents (n = 1,042) were separated into two age cohorts: women with PCOS aged 18-42 years (n = 935) and women with PCOS aged ≥43 years (n = 107). Data from the online survey were analyzed using descriptive statistics, Pearson correlations, and multiple regression …

Synthesis, Electrochemical And Photochemical Properties Of Sulfanyl Porphyrazine With Ferrocenyl Substituents, Mina Hassani, Amanda Leda, Weronika Porolnik, Michal Falkowski, Tomasz Rębiś, Jaroslaw Piskorz, Lukasz Popenda, Michal Wicinski, Dariusz T. Mlynarczyk, Nejat Düzgüneş, Michal P. Marszall

Pacific Faculty Work

Ferrocene is useful in modern organometallic chemistry due to its versatile applications in material sciences, catalysis, medicinal chemistry, and diagnostic applications. The ferrocene moiety can potentially serve many purposes in therapeutics and diagnostics. In the course of this study, (6-bromo-1-oxohexyl)ferrocene was combined with dimercaptomaleonitrile sodium salt to yield a novel maleonitrile derivative. Subsequently, this compound was subjected to an autocyclotetramerization reaction using the Linstead conditions in order to obtain an octaferrocenyl-substituted magnesium(II) sulfanyl porphyrazine. Following that, both compounds—the maleonitrile derivative and the porphyrazine derivative—were subjected to physicochemical characterization using UV-Vis, ES-TOF, MALDI-TOF, and one-dimensional and two-dimensional NMR spectroscopy. Moreover, the …

Fibrosis-The Tale Of H3k27 Histone Methyltransferases And Demethylases, Morgan D. Basta, Svetlana Petruk, Alexander Mazo, Janice L. Walker

Department of Biochemistry and Molecular Biology Faculty Papers

Fibrosis, or excessive scarring, is characterized by the emergence of alpha-smooth muscle actin (αSMA)-expressing myofibroblasts and the excessive accumulation of fibrotic extracellular matrix (ECM). Currently, there is a lack of effective treatment options for fibrosis, highlighting an unmet need to identify new therapeutic targets. The acquisition of a fibrotic phenotype is associated with changes in chromatin structure, a key determinant of gene transcription activation and repression. The major repressive histone mark, H3K27me3, has been linked to dynamic changes in gene expression in fibrosis through alterations in chromatin structure. H3K27-specific homologous histone methylase (HMT) enzymes, Enhancer of zeste 1 and 2 …

Adaptation Of A Community Health Outreach Model During The Covid-19 Pandemic: The Case Of The Mexican Consulates In The United States Of America, Pablo Gaitán-Rossi, Mireya Vilar-Compte, Arturo Vargas Bustamante

Department of Public Health Scholarship and Creative Works

The Ventanillas de Salud (VDS – “Health Windows”) are a culturally sensitive outreach program within the 49 Mexican Consulates in the United States that provides information and health care navigation support to underserved and uninsured Mexican immigrants. During the COVID-19 pandemic the VDS rapidly transitioned to remote operations adding new services. Based on the EquIR implementation framework, this qualitative study investigates how adaptations to improve emergency preparedness were performed. We conducted motivational interviews with three actors – six VDS coordinators, eight partner organizations, and ten VDS users– in two VDS, Los Angeles and New York, to document specific needs of …