Digital Commons Network^™

Vustruct: A Compute Pipeline For High Throughput And Personalized Structural Biology, Christopher W. Moth, Jonathan H. Sheehan, Abdullah Al Mamun, R. Michael Sivley, Alican Gulsevin, David C. Rinker, Zenab F. Mchaourab, Undiagnosed Disease Network, John A. Capra, Jens Meiler

2020-Current year OA Pubs

Effective diagnosis and treatment of rare genetic disorders requires the interpretation of a patient's genetic variants of unknown significance (VUSs). Today, clinical decision-making is primarily guided by gene-phenotype association databases and DNA-based scoring methods. Our web-accessible variant analysis pipeline, VUStruct, supplements these established approaches by deeply analyzing the downstream molecular impact of variation in context of 3D protein structure. VUStruct's growing impact is fueled by the co-proliferation of protein 3D structural models, gene sequencing, compute power, and artificial intelligence. Contextualizing VUSs in protein 3D structural models also illuminates longitudinal genomics studies and biochemical bench research focused on VUS, and we …

The Camus Initiative: A Multiphase, Multicentre International Collaboration To Redefine Risk Stratification, Reporting, And Grading Of Surgical Complications In Urology., Christopher Soliman, Niranjan J. Sathianathen, Niall M. Corcoran, Nathan Lawrentschuk, Patrick Y. Wuethrich, Marc A. Furrer, Paul Chung, Camus Study Group Collaborators

Department of Neurology Faculty Papers

Surgical complications remain a major source of preventable morbidity, mortality, and health care expenditure, but existing frameworks such as the Clavien-Dindo classification and Comprehensive Complication Index are clinician-centred and intervention-focused and fail to capture cumulative patient-centred outcomes. This protocol outlines the Complications After Major and Minor Urological Surgery (CAMUS) initiative, a global, multiphase effort to redefine complication reporting, risk stratification, and outcome measurement in urological surgery. CAMUS aims to address these limitations via an integrated, seven-arm programme combining retrospective and prospective data analysis, consensus development, and digital infrastructure design. Arm 1 has assembled a retrospective data set of 130 034 …

Use And Awareness Of Online Resources In University Libraries, Rudraksha Gouridevi

Library Philosophy and Practice (e-journal)

The study of the use and awareness of online resources in university libraries. The study used a survey to collect primary data. A questionnaire was used to collect primary data from library users (undergraduate, postgraduate students, and research scholars) in selected university libraries, both public and Deemed University libraries, in Andhra Pradesh. The study covered four university libraries. Out of the total number of students and research scholars (25266) from the four universities. In this study, only 10 percent of the respondents were selected as the survey sample. The study indicated that the highest rate of users are accessing the …

Computational Fluid Dynamics-Based Risk Stratification Of Modified Blalock-Taussig-Thomas Shunt Thrombogenicity, Yi Qiao, Ethan Penn, Jacob Miller, Scott Bugenhagen, Ram Rohatgi, Kelsey Mercer, Blaire Kulp, Jinli Wang, Pirooz Eghtesady, Guy M Genin, Edon J Rabinowitz, David Bark

2020-Current year OA Pubs

BACKGROUND: The modified Blalock-Taussig-Thomas shunt (mBTTS) is a critical palliative procedure for infants with single-ventricle physiology, but thrombosis-related occlusion affects 8% to 12% of infants and carries nearly 50% mortality. Meanwhile, existing antithrombotic strategies fail to address the hemodynamic factors driving thrombosis, highlighting the need for a deeper understanding of flow dynamics in shunt failure.

OBJECTIVES: This study aims to identify how mBTTS geometry influences hemodynamics and thrombosis risk, providing quantitative guidance for surgical planning and shunt design optimization.

METHODS: We used patient-specific imaging data to test 54 idealized mBTTS configurations, systematically varying key geometric factors: pulmonary artery diameter, shunt …

Sustainment Of Hydroxyurea Adherence In Patients With Sickle Cell Disease, Andrew M Heitzer, Zachary Wooten, Guangjin Luo, Marsha Treadwell, Allison A King, Victor R Gordeuk, Nirmish Shah, Christina M Abrams, Sarah Mccuskee, Siera Gollan, Jennifer Longoria, Jane S Hankins, Sickle Cell Disease Implementation Consortium

2020-Current year OA Pubs

IMPORTANCE: Despite established treatment guidelines and strong therapeutic benefit, hydroxyurea remains underused among patients with sickle cell disease.

OBJECTIVE: To assess the change in self-reported hydroxyurea use (ie, taking the medication at all) and adherence (ie, the number of days taken per week) over time and to examine factors associated with the trajectory of hydroxyurea use and adherence.

DESIGN, SETTING, AND PARTICIPANTS: Data were collected through the Sickle Cell Disease Implementation Consortium, a longitudinal, multicenter, observational cohort study that recruited patients from 8 centers across the US. Data collection occurred from 2017 to 2022, and analyses were performed from January …

Cognitive Behavioral Therapy For Individuals With Low Literacy And Perinatal Depression: A Randomized Clinical Trial, Eliza Kleban, Ashleen Lee, Aminata Koroma, D Taylor Hendrixson, Joshua Duncan, Mark J Manary, Kevin B Stephenson

2020-Current year OA Pubs

IMPORTANCE: Perinatal depression is common in sub-Saharan Africa, yet treatment gaps are substantial. Cognitive behavioral therapy (CBT) is effective but relies on written materials.

OBJECTIVE: To evaluate the efficacy of a culturally adapted CBT intervention delivered by lay counselors to women with perinatal depression in rural Sierra Leone.

DESIGN, SETTING, AND PARTICIPANTS: This study was an individually randomized, outcomes assessor- and investigator-blinded, clinical trial of an adapted CBT intervention vs enhanced usual care. The trial was conducted in 6 government-run antenatal clinics in Pujehun District, Sierra Leone, which has limited infrastructure, low literacy, high maternal undernutrition, and no perinatal mental …

Advancing Peripheral Nerve Regeneration (Nerve Space 2025), Ken Porche, Tara Sara Saffari, Hollie Power, Wesley P Thayer, S Shelby Burks, John C Elfar, Alexander Y Shin, David M Brogan

2020-Current year OA Pubs

UNLABELLED: Peripheral nerve injuries remain a major clinical challenge due to slow axonal regeneration, rapid Wallerian degeneration (WD), and degeneration of target organs prior to reinnervation.

WHERE ARE WE NOW?: Strategies to enhance regeneration can be broadly divided into three categories: preventing or delaying WD, speeding up axonal regeneration, and improving the molecular environment at the injury site. Approaches to delay WD include polyethylene glycol-mediated axonal fusion, which may restore early axonal continuity and conduction, and inhibition of sterile alpha and TIR motif-containing 1, the central executioner of WD, with small-molecule inhibitors now in clinical trials. Methods to accelerate axon …

Use And Public Reporting Of Predetermined Change Control Plans For Ai-Enabled Medical Devices, Patryk A Dabek, Florence T Bourgeois, Ariel D Stern, Yi Zhu, Alexander O Everhart

2020-Current year OA Pubs

No abstract provided.

Cultural Dimensions And Ethical Perceptions Of Tax Evasion In The Digital Tax Reporting Era, Renna Magdalena, Henny Cheirine

International Conference on Business and Management Research (ICBMR)

Tax evasion is still a significant challenge for Indonesia's state revenue. This study examines how Hofstede's cultural dimension affects the ethical perception of tax evasion in Javanese MSME owners to overcome the gap in understanding of cultural factors that affect tax compliance behaviour at the individual level. In the context of a tax reporting system that has been fully digitised through e-filing and online applications, it is important to understand that the existence of technology does not necessarily remove the moral rationale for fraudulent acts. A quantitative survey was conducted on 112 MSME owners. Using validated instruments, the study used …

A Human-Technology Centered Sustainability Framework For Digital Transformational Leadership And Ai In Indonesian Islamic Non-Profit Organizations, Ardi Ardi, Yohana Fcp Meilani, Margaretha Pink Berlianto, Sylvia Samuel Dr., Maureen Arthajaya Ms.

International Conference on Business and Management Research (ICBMR)

This study promotes a Human-Technology Centered Sustainability paradigm by examining how artificial intelligence (AI) and digital transformational leadership intersect within Indonesian Islamic non-profit organizations. It moves beyond viewing AI as a mere tool, instead assessing organizational readiness for adoption and identifying areas for strategic development. The research emphasizes aligning AI with human values, social equity, and individual dignity, advocating for ethical integration that respects humanistic principles. Using an exploratory methodology literature review, organizational report analysis, and publication trend mapping the study highlights the need for collaborative policy-making, ethical frameworks, and innovation to ensure sustainable human-technology interaction. Key ethical concerns include …

One For All, All For Innovation: Transforming The Indonesia’S Public Sector Through Ambidextrous Leadership, Dian Mulia Sari, Elok Savitri Pusparini

International Conference on Business and Management Research (ICBMR)

In an era defined by volatility, uncertainty, complexity, and ambiguity (VUCA), public sector organizations face increasing pressure to innovate. This study examines how ambidextrous leadership influences innovative work behavior (IWB) among civil servants, with psychological ownership (PO) serving as a mediator. Using a quantitative approach, data were collected from 152 structural and functional officials within Indonesia’s State Finance Organization (OKN) and analyzed using PLS-SEM. The results indicate that ambidextrous leadership has a significant direct effect on IWB. More importantly, psychological ownership mediates this relationship through two distinct pathways: promotive PO strengthens IWB by fostering confidence and proactive contribution, while preventive …

Driving Innovative Work Behavior In The Public Sector: The Roles Of Transformational Leadership And Change Management, Hafsah Fibrihirzani, Elok Savitri Pusparini

International Conference on Business and Management Research (ICBMR)

Innovative work behavior is a strategic factor in strengthening innovation capacity in the public sector and fostering an innovative organizational climate. Understanding how transformational leadership and change management contribute to innovative work behavior is therefore essential for enhancing performance and sustainability in public organizations. This study analyzes the influence of transformational leadership on employees’ innovative work behavior, with change management as a mediating variable.

The study used a quantitative approach, with data collected from 159 employees of a public research institution. Data were analyzed using Structural Equation Modeling (SEM) with the Partial Least Squares (PLS) technique to examine both direct …

Cutting Red Tape In Research: A Business Process Improvement Approach For The Riim Collaboration Scheme, Novia Nurul Fatmawati, Arviansyah Arviansyah

International Conference on Business and Management Research (ICBMR)

Strengthening the national research and innovation ecosystem is crucial for sustainable development, with the government playing a key role through strategic funding schemes. The Research and Innovation for Advanced Indonesia (RIIM) Collaboration scheme, managed by the National Research and Innovation Agency (BRIN), is vital for fostering international research partnerships. However, its implementation faces significant challenges, including lengthy and complex business processes that lead to delays in research execution. This study aims to analyze the current (as-is) business process of the RIIM Collaboration scheme and design an optimized (to-be) process to enhance operational efficiency. This research employs a mixed-method case study …

Beyond Bureaucracy: Entrepreneurial Mindset And Ai Readiness As Drivers Of Business Model Innovation In Blu Business Units — A Conceptual Framework, Ahmad Nurholis, Muhammad Rifky Adzakie

International Conference on Business and Management Research (ICBMR)

This paper advances a conceptual framework that examines how entrepreneurial mindset (EM) and AI readiness interact to shape business model innovation (BMI) and financial performance (FP) within Indonesia’s profit-oriented Public Service Agency (BLU) business units. As hybrid organizations, BLU business units must simultaneously fulfill their public service mandate while pursuing revenue generation, creating a unique context that demands stronger theoretical grounding. The framework draws on New Public Management (NPM) principles and the Dynamic Capabilities (DC) perspective to argue that an entrepreneurial mindset stimulates BMI both directly and indirectly through enhanced AI readiness. In turn, BMI is positioned as a driver …

Ai As A Catalyst For Managerial Strategy Transformation: Operational Efficiency And Business Model Innovation, Nazilatul Hidayah

International Conference on Business and Management Research (ICBMR)

This study investigates how Artificial Intelligence (AI) serves as a catalyst for managerial strategy transformation, focusing on two critical areas: operational efficiency and business model innovation. Drawing on multiple case studies, the paper analyzes how companies such as Unilever, Wayfair, Amazon, and Alibaba integrate AI technologies into their strategic processes. Results show that AI implementation has enabled cost reductions of up to 15-20%, improved throughput in logistics operations, and enhanced personalization strategies that significantly impact revenue. For instance, Alibaba attributes approximately 35% of its sales volume to AI-powered recommendation systems. These outcomes demonstrate that AI not only improves operational workflows …

3t Of Tech, Taste, And Transformation In Coffeepreneurship, Razinda Tasnim Abdul Rahim, Mohd Faizuddin Muhammad Zuki, Nur Syamilah Md Noor

International Conference on Business and Management Research (ICBMR)

The global coffee industry is rapidly transforming due to digitalization, evolving consumer preferences, and sustainability trends. Coffeepreneurship, blending entrepreneurial innovation with coffee culture, has emerged as a competitive business model. This study applies the 3T- Technology, Taste, and Transformation to assess digital innovation, consumer experience, and business adaptation in coffee entrepreneurship. Despite opportunities in digital transformation, coffeepreneurs face challenges such as market saturation, financial constraints, and regulatory barriers. Limited access to fintech solutions and supply chain inefficiencies further hinder scalability. This study addresses these gaps by analyzing how technology, branding, and financial literacy influence coffeepreneurs' long-term sustainability using the VRIO …

Sharia Compliance And Stock Price Crash Risk: Evidence From Indonesia, Asty Khairi Inayah Syahwani, Arief Wibisono Lubis, Dwi Nastiti Danarsari

International Conference on Business and Management Research (ICBMR)

This study examines the impact of sharia compliance on stock price crash risk, controlling for company fundamental characteristics, among firms listed on the Indonesia Stock Exchange from 2021 to 2024. Panel data was analyzed using a dynamic panel model (System GMM) and crash risk is measured using NCSKEW and DUVOL. The results show that Sharia compliance significantly reduces stock price crash risk when measured using NCSKEW, while its effect on DUVOL is insignificant. This finding is consistent with the robustness check using the two-step System GMM, suggesting that Sharia principles can be a mitigating mechanism for extreme crash risk. These …

Fintech Innovation And Strategy In Islamic Financial Services In Indonesia: Mapping Trends And Correlations Through Digital Content Analysis, Faisal Binsar S.T., M.M.S.I, Dr., Muhammad Bayu Drs., M.M., Dr., Arif Budiman S.Kom, M.Kom, Lisa Puspitasari S.E., M.Si., Dr.

International Conference on Business and Management Research (ICBMR)

This study explores the impact of fintech innovations and strategies on the operational efficiency and service quality of Islamic financial services in Indonesia, emphasizing their alignment with Islamic financial principles. Using a descriptive quantitative methodology, the research employs digital content analysis of online reviews and social media discussions to uncover key themes. Advanced analytic techniques, including topic modeling with Gibbs Sampling for Dirichlet Multinomial Mixture (GSDMM) and cosine similarity for inter-topic correlation analysis, are applied to data sourced from various digital platforms. The findings reveal three dominant themes: media and community interaction, the performance and services of Islamic financial institutions, …

Project Scheduling Analysis For The Overhaul Of Indramayu Steam Power Plant (Pltu), Hano Kharismantoko, Ratih Dyah Kusumastuti

International Conference on Business and Management Research (ICBMR)

This study aims to analyze time and cost efficiency in the overhaul project of PLTU Unit 2 Indramayu by applying project crashing using mixed method approach. The growing electricity demand in Indonesia and the vital role of Steam Power Plants (PLTU) require effective maintenance strategies to prevent revenue losses due to overhaul project delays. The research integrates qualitative insights from direct observation and interviews with quantitative data from project documentation. The Work Breakdown Structure (WBS) and Critical Path Method (CPM) were used to identify critical activities, followed by project crashing using linear programming approach to determine the optimal schedule and …

Designing Digital Marketing Through Generative Ai For Koperasi Merah Putih Urban, Alfonsius Alfonsius, Daniel Cassa Augustinus, Ricky Banke

International Conference on Business and Management Research (ICBMR)

This qualitative study examines the potential of Generative Artificial Intelligence (GenAI) to strengthen digital marketing strategies for urban cooperatives, focusing on Koperasi Merah Putih Urban in Medan, Indonesia. Despite cooperatives playing a crucial role in promoting inclusive economic growth, many remain dependent on offline promotion, facing challenges of visibility, uneven member engagement, and lack of sustainable governance structures. Using a juridical-empirical case study approach, data were collected through semi-structured interviews with cooperative officials and MSME actors, observation of cooperative communities, and analysis of legal and policy documents. Thematic analysis revealed three key issues: limited visibility due to inconsistent branding, unequal …

Analysis The Influence Of Product Attributes On Purchase Decision In Choosing A Smartphone Apple Or Samsung., Arumadina Islamiq, Indrawati Indrawati

International Conference on Business and Management Research (ICBMR)

Smartphones are currently a very important and necessary means of communication for the public. Two of the most popular smartphone brands are Samsung and Apple. The purpose of this study is to measure respondents' assessments of product attribute variables (quality, features, brand, design style, and support services) in purchase decisions.

This research is descriptive. It uses quantitative methods. This study examines two variables in detail, namely product attributes (X) as the independent variable and Purchase Decision (Y) as the dependent variable. The respondents in this study consisted of all consumers who currently use Samsung or Apple smartphone products, with 400 …

Predicting Medical Tourism Destination Preference Of Indonesian Patients: The Roles Of Patient Experience Quality, Perceived Ai Intelligence And Humanness, Eddy Eddy, Sabrina O. Sihombing, Ferdi Antonio

International Conference on Business and Management Research (ICBMR)

This study proposes an investigation on the antecedents of medical tourism destination preference among Indonesian patients, with a specific focus on the novel moderating role of Artificial Intelligence (AI) chatbots. Driven by a significant financial drain from outbound medical travel, this study aims to understand the key factors that influence Indonesian patients to seek care abroad. The proposed conceptual framework posits that medical tourism destination preference is positively predicted by medical technology advancement, service quality, price transparency, and geographical accessibility. Patient experience quality is also hypothesized to mediate these relationships, serving as a critical psychological bridge. The most innovative aspect …

Unraveling The Evolution Of Customer Perspectives In Ride-Hailing And Ridesharing: A Bibliometric Analysis, Arga Hananto, Rhenald Kasali Ph.D, Sri Rahayu Hijrah Hati Ph.D

International Conference on Business and Management Research (ICBMR)

Ride-sourcing services (i.e., ride-hailing and ridesharing)—represent one of the fastest-growing segments of the sharing economy. Although their success fundamentally depends on customer engagement, scholarly reviews have often focused more on operational and technical developments than on customer behavior, satisfaction, and loyalty. This study examines the evolution of ride-sourcing research during the COVID and post-COVID period (2020–2025) through a bibliometric and content analysis of 297 journal articles retrieved from Scopus. While earlier reviews often emphasized operational and technological aspects, this analysis focuses on customer-centered perspectives such as adoption, satisfaction, loyalty, and attitudes.

The findings show a substantial increase in research output …

Job Seeking Or Creating An Exploratory And Confirmatory Study In Higher Education, Dian Rachmawati, Sheerad Sahid, Mohd. Izwan Mahmud

International Conference on Business and Management Research (ICBMR)

This study examines the career pathways of economics education students in Indonesia, focusing on their orientation toward job seeking or entrepreneurial creation while exploring the educator’s role through the lens of equity and inclusion. Using a quantitative approach, this research employed Exploratory Factor Analysis (EFA) in a pilot phase with 120 participants, followed by Confirmatory Factor Analysis (CFA) with 455 respondents drawn through stratified random sampling from seven major universities offering economics education programs across Indonesia. The instrument’s content validity was confirmed by five expert reviewers, and its construct validity and reliability were tested using SPSS version 26 through factor …

Assessing The Impact Of Economic And Social Dynamics On Domestic Tourism In Indonesia: An Econometric And Cluster Analysis, Darol Arkum, Mudrajad Kuncoro, Ghardapaty Ghaly Ghiffary, Diah Setyorini Gunawan

International Conference on Business and Management Research (ICBMR)

ABSTRACT

Introduction: A strategic method of evaluating the economic impact of tourism across regions while taking into consideration Indonesia's geographical and socioeconomic diversity is to divide tourist destinations according to the reasons for travel. Background Problems: This study introduces an integrated statistical framework to assess the economic impact of domestic tourism in Indonesia, emphasizing regional heterogeneity and evolving travel behavior. Research Methods: A novel clustering approach is developed based on travel motivations—rather than geographical proximity—utilizing hierarchical clustering in conjunction with time series analysis and ANOVA techniques. The time series analysis identifies pronounced seasonal trends and fluctuations in spending, influenced significantly …

The Voice As A Coordinated Bodily System: Embodied Learning, Anatomy, And Vocal Pedagogy, Ge Hope Tian

The Transdisciplinary STEAM+ Journal

This reflective article examines the limitations of control-based approaches in traditional vocal training and proposes a shift toward understanding the voice as an integrated, coordinated bodily system. Drawing on personal experience, the author highlights how common instructional language - focused on outcomes such as resonance, support, and projection - often leads singers to apply excessive effort, resulting in tension, inefficiency, and vocal strain. By distinguishing between localized control and whole-body coordination, the reflection illustrates how sustainable vocal function emerges not through muscular manipulation but through balanced, dynamic organization of breath, posture, and sound. The author traces a transformative learning process …

Art As Resistance, Art As Hope: The Crane, The Nopal, And The Knowledge They Carry, Mayra Urbina

The Transdisciplinary STEAM+ Journal

This reflection explores the crane-and-nopal motif in Talavera Poblana ceramics as a lens for understanding artisan knowledge, cultural identity, and the impacts of globalization on Indigenous communities. Through my own painting of a Talavera-style vase, I trace the layered colonial history embedded in this motif — including the quiet resistance of Indigenous artisans who encoded Aztec memory into colonial art forms by replacing the eagle with the crane. The reflection examines how globalization threatens artisan traditions through fast-fashion appropriation, the limitations of Mexico's 2022 cultural heritage protection law, and the displacement of Indigenous artisans in Mexico City. Ultimately, I argue …

The Secret Science Of Songs. Created By All Children Everywhere, Paul G. Morehouse Phd

The Transdisciplinary STEAM+ Journal

This field article introduces The Secret Science of Songs, a research-informed, practice-based framework that reconceptualizes songs as powerful, transdisciplinary tools in early childhood education. Drawing on over 40 years of classroom-based action research alongside established findings in cognitive science and music perception, the framework argues that young children’s engagement with songs is rooted not primarily in performance skill, but in their innate capacity to perceive and process auditory patterns in music and language. These pattern-based experiences constitute a rich aesthetic and cognitive domain through which children construct meaning, long before mastery of melody or verbal precision emerges.

The article …

Show And Tell: Integrating The Arts Into Transdisciplinary Public Health And Community Organizing Education, Bree L. Hemingway, Margaret Hawkins

The Transdisciplinary STEAM+ Journal

This field note examines the integration of arts-based pedagogy into a transdisciplinary graduate course that brings together students from public health, medicine, the social sciences, humanities, education, technology, and the arts. Central to the course is the Show and Tell assignment, in which students select and present a work of art connected to a social movement. Over three years and 42 student submissions, this assignment has served as an accessible entry point for exploring how artistic expression shapes activism, fosters community, and deepens understanding of justice-oriented work. Through an inductive content analysis of student-selected artworks and presentations, five major thematic …

Chromatic Meditations, Jessica Csanky

The Transdisciplinary STEAM+ Journal

My reflection traces the development of In Harmony, a cross-cultural exhibition created in collaboration with Japanese artist Hisakazu Suzuki, emerging from a chance encounter and realized through a shared commitment to peace. Presented at the 4th Annual Peace Conference, the exhibition explores how artistic practice can transcend language and cultural boundaries to foster connection, hope, and collective vision during a time of global uncertainty. Centered on my series Chromatic Meditations, the work investigates the inner dimensions of peace through mindful, ritual-based painting practices shaped by pregnancy and the anticipation of new life. These emotionally resonant color-field landscapes invite …