Digital Commons Network^™

Human-Animal Interactions And Edibility?, Andrew N. Rowan

WellBeing News

Does a growing pet-keeping culture affect other human-animal interactions?

Enhancing Parental Support For Stem Students, Rebecca Stull Zundel

Instructional Psychology and Technology Graduate Student Projects

This project report explores the design and implementation of instructional resources aimed at enhancing parental support for STEM students within the Army Educational Outreach Program (AEOP). Through a human-centered approach, the project addresses the need for parental involvement in fostering students' STEM education and career exploration. Drawing on multiple design principles and theories, the project aims to empower parents with the knowledge and skills necessary to provide informed guidance and support in STEM fields. The design process involves a comprehensive analysis of learner needs, environmental factors, and project constraints, resulting in the development of self-directed resources tailored to the specific …

Can Climate Change Constitute A Taking? The Endangered Species Act And Greenhouse Gas Regulation, Ethan Mooar

Colorado Environmental Law Journal

No abstract provided.

Perinuclear Damage From Nuclear Envelope Deterioration Elicits Stress Responses That Contribute To Lmna Cardiomyopathy, Kunal Sikder, Elizabeth Phillips, Zhijiu Zhong, Nadan Wang, Jasmine Saunders, David Mothy, Andrew Kossenkov, Timothy Schneider, Zuzana Nichtova, György Csordás, Kenneth B. Margulies, Jason C. Choi

Center for Translational Medicine Faculty Papers

Mutations in the LMNA gene encoding lamins A/C cause an array of tissue-selective diseases, with the heart being the most commonly affected organ. Despite progress in understanding the perturbations emanating from LMNA mutations, an integrative understanding of the pathogenesis underlying cardiac dysfunction remains elusive. Using a novel conditional deletion model capable of translatome profiling, we observed that cardiomyocyte-specific Lmna deletion in adult mice led to rapid cardiomyopathy with pathological remodeling. Before cardiac dysfunction, Lmna-deleted cardiomyocytes displayed nuclear abnormalities, Golgi dilation/fragmentation, and CREB3-mediated stress activation. Translatome profiling identified MED25 activation, a transcriptional cofactor that regulates Golgi stress. Autophagy is disrupted …

The Importance Of Intergenerational Leadership In Organizations, Kelta Tabaku Ms.

M.S. in Leadership

Abstract

This study delved into the details of leadership within intergenerational settings, spotlighting the pivotal role of effective communication and cultural comprehension. It underscores how intergenerational leadership shapes organizational dynamics, necessitating innovative methods and meticulous succession planning. The research emphasizes the imperative of acknowledging each generation's distinct contributions and the deployment of leadership training and mentorship initiatives to cultivate inclusive leadership spanning generations. This capstone research thesis aims to explore the challenges in executing effective intergenerational leadership practices in contemporary organizations, potentially uncovering issues like communication barriers, change resistance, or generational misunderstandings. The hypothesis posits that adeptly implemented intergenerational leadership …

Kiwiberry Breeder Is Unh’S 2024 Innovator Of The Year, Allison Bell

UNH Today Archive

No abstract provided.

Outpatient Administration Of Car T-Cell Therapy: A Focused Review With Recommendations For Implementation In Community Based Centers, Ariel Perez, Tiba Al Sagheer, George Nahas, Yuliya Linhares

All Publications

Chimeric Antigen Receptor T-cell (CAR-T) therapy has transformed the treatment landscape for hematological malignancies, showing high efficacy in patients with relapsed or refractory (R/R) disease and otherwise poor prognosis in the pre-CAR-T era. These therapies have been usually administered in the inpatient setting due to the risk of cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). However, there is a growing interest in the transition to outpatient administration due to multiple reasons. We review available evidence regarding safety and feasibility of outpatient administration of CD19 targeted and BCMA targeted CAR T-cell therapy with an emphasis on the …

Dnp Final Report: Effects Of Open-Access Scheduling On Patient No-Show Rates In An Outpatient Clinic, Maria Aileen A. Wilkinson Msn, Mba, Rn

DNP Final Reports

No-show rates in a South Texas outpatient clinic have been as high as 16% to 20% which increases wait times to be seen in the clinic and decreases patient access to outpatient care. This no-show rate data has continued despite multiple interventions that have been implemented in an academic health science center. Physical, socio-economic, geographic, and health/lifestyle factors affecting no show or missed appointments are crucial to determining the most appropriate interventions to alleviate this issue. No-show rates are important metrics to improve because it directly affects the organization's revenue, access to care, and appointment wait times. Research evidence regarding …

The North Central Extension Risk Management Education Center, Part I: Helps Producers Manage Risks, Christine Lockert, Sheila Aikanathan Johnson, Bradley D. Lubben

Cornhusker Economics

Established in 2001, the North Central Extension Risk Management Education Center (NCERMEC) has a long history of supporting risk management education programs serving producers in the region. Located at the University of Nebraska-Lincoln Agricultural Economics Department, the Center is one of four regional Extension Risk Management Education (ERME) Centers located throughout the country. ERME is funded through USDA’s National Institute of Food and Agriculture (NIFA) and was authorized by the Agricultural Risk Protection Act of 2000. The fundamental purpose of the ERME program is to educate producers to manage risk and position their farm or ranch for future growth and …

Exome Sequencing Implicates Ancestry-Related Mendelian Variation At Syne1 In Childhood-Onset Essential Hypertension, Ian Copeland, Edmond Wonkam-Tingang, Monesha Gupta-Malhotra, S Shahrukh Hashmi, Yixing Han, Aarti Jajoo, Nancy J Hall, Paula P Hernandez, Natasha Lie, Dan Liu, Jun Xu, Jill Rosenfeld, Aparna Haldipur, Zelene Desire, Zeynep H Coban-Akdemir, Daryl A Scott, Qing Li, Hsiao-Tuan Chao, Ana M Zaske, James R Lupski, Dianna M Milewicz, Sanjay Shete, Jennifer E Posey, Neil A Hanchard

Faculty, Staff and Student Publications

Childhood-onset essential hypertension (COEH) is an uncommon form of hypertension that manifests in childhood or adolescence and, in the United States, disproportionately affects children of African ancestry. The etiology of COEH is unknown, but its childhood onset, low prevalence, high heritability, and skewed ancestral demography suggest the potential to identify rare genetic variation segregating in a Mendelian manner among affected individuals and thereby implicate genes important to disease pathogenesis. However, no COEH genes have been reported to date. Here, we identify recessive segregation of rare and putatively damaging missense variation in the spectrin domain of spectrin repeat containing nuclear envelope …

Liquid-Phase Adsorption Of Dimethyl Methylphosphonate On Poly(Ether Imide) And Its Metal Hydroxide-Integrated Composites, Sukanta K. Mondal, Peter O. Aina, Ali A. Rownaghi, Fateme Rezaei

Chemical and Biochemical Engineering Faculty Research & Creative Works

Understanding the Adsorption Behavior of Dimethyl Methylphosphonate (DMMP), a Key Simulant for Some Nerve Agents, is Crucial for Developing Effective Protective Measures and Ensuring Environmental Safety Against Harmful Chemical Warfare Agents. This Study Systematically Explores the Liquid-Phase Adsorption of DMMP over Branched Poly (Ether Imide) (Ultem) and its Ce (OH)4/Zr (OH)4 Metal Hydroxide Composites. Utilizing UV-Visible (UV-Vis) Spectroscopy, the Adsorption Process Was Monitored over Time to Analyze the Interplay between Various Ultem-Based Composites and DMMP Molecules. Nonreactive Ultem Materials Were Experimentally Identified as Suitable Adsorbents for Liquid-Phase DMMP Capture, Providing a Novel Avenue for Protective Filtration Technologies. It Was Found …

Role Of Integrase-Pp2a Interaction In Human T-Cell Leukemia Virus Type-1 Replication And Pathogenesis, Shayna Turbin

Senior Honors Papers / Undergraduate Theses

Human T-cell leukemia virus type-1 (HTLV-1) is an oncogenic retrovirus that causes multiple disorders, including adult T-cell leukemia and HTLV-1-associated myelopathy/tropical spastic paraparesis. HTLV-1 retroviral integrase binds to the regulatory B’56γ subunit of the host cell Protein Phosphatase 2A (PP2A). Integrase contains a highly conserved LxxIxE motif that is essential for binding, which increases integration efficiency and facilitates HTLV-1 hijack of host cell machinery. We aim to understand how mutations introduced in the highly conserved binding site can affect viral particle production and infectivity. We transfected 729B human lymphoblastoid cells and 293T cells with mutant and wildtype virus. Mutations L213A, …

St-03 - Kansas 2024-05-08, Maribeth Shafer

State Representatives

No abstract provided.

Pennsylvania School Social Workers’ Trauma-Informed Practices: Status And Future Needs, Jessica L. Schoonmaker

Social Work Doctoral Dissertations

The idea of trauma-informed practices is a broad concept that can be utilized to create a safe environment in which individuals, families, communities and organizations that have been exposed to trauma can be and feel supported. Trauma-informed practices are important due to the pervasive nature of trauma exposure (Kilpatrick et al., 2013). Traumatic experiences can impact individuals’ physical and mental health over the course of their lifespans (Avery, et al., 2021; Centers for Disease Control, 2021; Gonzalez et al., 2016; McWey, 2020; Mersky et al., 2019; Porche et al., 2016; SAMHSA, 2014a; Trauma Informed Care Implementation Resource Center, 2021; Zyromski …

Clearing The Light Path: Proteoglycans And Their Important Roles In The Lens And Cornea, Mary Ann Stepp, A. Sue Menko

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Some of the earliest studies of glycans were performed on mammalian corneas and lenses with many of the key concepts we currently recognize as being fundamental to our understanding of basic cell biology arising from these studies. Proteoglycans and their GAG side chains are essential components of the ECM of the lens capsule. They also are present in the anterior corneal epithelial basement membrane and the posterior (Decemet's) basement membrane, and they organize collagen fiber diameters and spacing in the corneal stroma to maintain stromal clarity. Studies using genetically engineered mice and characterization of spontaneously arising mutations in genes controlling …

A Bilevel Approach To Resource Allocation For Utility-Based Request-Response Systems, Tanner Jack Sundwall

Theses and Dissertations

We present a novel bilevel programming formulation that aims to solve a resource allocation problem for request-response systems. Our formulation is motivated by potential inefficiencies in the allocation of computational resources to incoming user requests in such systems. In our experience, systems often operate with a surplus of resources despite potentially incurring unjustifiable cost. Our work attempts to optimize the tradeoff between the financial cost of resources and the opportunity cost of unfulfilled user demand. Our bilevel formulation consists of an \textit{upper} problem which has a constraint value appearing in the \textit{lower} problem. We derive efficient methods for finding global …

The Effects Of Relationship Quality And Duration On Negative Word-Of-Mouth After A Low-Contact Service Failure, Tuğberk Kara, Tugba Tugrul

Marketing Faculty Publications

This article examines the effects of relationship quality (RQ) and relationship duration (RD) on negative word-of-mouth (WoM) after a low-contact service failure. Partial least square structural equation modeling was used to analyze the data collected through a scenario-based online survey (n=153). First, unlike the inconsistent findings in high-contact service research, the results showed that RQ led to decreased negative WoM in low-context service failures, namely telecommunication. Second, this research contributes to the literature by revealing the negative effect of RD on customers’ tendency to spread negative WoM. In addition, RD did not moderate the relationship between RQ and negative WoM.

Predictors Of Work Styles And Transition Success From Military Service To The Civilian Workforce, Ryan Nicholas Schuler

Walden Dissertations and Doctoral Studies

Upon leaving the armed forces, service members face challenges transitioning to the civilian workforce. The relationship between service members’ work styles and successfully transitioning to the civilian workforce is unknown. It is also unknown if military occupation (MO) affects the relationship between work styles and transition success. Although researchers have investigated the transition from active military service to the civilian workforce, they have not focused on identifying predictors of transition success. Three theories, positive psychology, transformational learning theory, and career decision-making theory, were used as the foundation of the study and to develop the research questions to determine the success …

Primary School Teachers’ Perspectives On Parent-Teacher Engagement In A Rural Title I Charter School District In The Southeast, Deena K. Eberhardt

Walden Dissertations and Doctoral Studies

Children learn more effectively when parent-teacher engagement is high and home-school communication and collaboration are optimal. The problem addressed in this study was a lack of parent-teacher engagement in two Title I primary schools within a charter school system located in a rural area of the Southeast. The purpose of this basic qualitative study was to explore primary teachers’ perspectives on parent-teacher engagement in a rural Title I charter school system in the Southeast. Epstein’s parental involvement model and Vygotsky’s social constructivist theory formed the conceptual framework. Research questions focused on teachers’ perspectives on parent-teacher engagement and strategies encourage this. …

Impact Of Covid-19 On Opioid Misuse, Mental Health, And Substance Abuse Treatment Of Adults, David Stephen Reed

Walden Dissertations and Doctoral Studies

The purpose of this quantitative cross-year comparison of two cross-sectional studies was to examine whether there is an impact of the COVID-19 pandemic on opioid misusers seeking mental health and substance abuse treatment, taking into consideration the social, ecological, and economic factors of age, gender, poverty status, and county of residence metropolitan status. The theoretical foundations of this study are the social-ecological framework in terms of the geographic and economic impacts, and the structural and social determinants of health framework to examine the influences of economic and community on individual behaviors, to answer the research questions while controlling for the …

Lived Experiences Of Congolese Women With Postpartum Family Planning Counseling In The United States, Lemba Dina Nshisso

Walden Dissertations and Doctoral Studies

Postpartum family planning counseling experience among immigrant women in the United States has primarily involved Latina immigrant women, with little focus on African immigrant women. To address this gap, a phenomenological study was conducted to examine lived experiences of Congolese immigrant women living in the United States (U.S.) with postpartum counseling and how this type of counseling influences their decision-making processes. Additionally, the study involved understanding Congolese immigrant women’s interactions with healthcare services for family planning procurement. Data were collected from 10 Congolese immigrant women who had given birth in the U.S. and attended a postpartum family planning counseling session. …

A Qualitative Exploration Of Early Educator Retention And Within-Year Turnover, Elizabeth Ann Dupin

Walden Dissertations and Doctoral Studies

Early childhood education and care (ECEC) programs are experiencing high turnover, resulting in lower teacher retention rates. High turnover hinders program quality, creates financial strain, and adversely affects program sustainability. Despite efforts to increase educator retention, a rural midwestern ECEC program’s administrative team continues to experience declining retention and high within-year turnover. This study aims to explore early educators’ perceptions of the organizational factors that contribute to teacher retention and within-year turnover in the selected ECEC site. The research study explores organizational factors using Herzberg’s two-factor theory of motivation. The qualitative data collected from current and previous early educators employed …

Health Care Utilization And Behavior Changes After Workplace Genetic Testing At A Large Us Health Care System, Elizabeth Charnysh, Subhamoy Pal, Jonathan Reader, Wendy R. Uhlmann, Sarah Mccain, Kunal Sanghavi, Drew Blasco, Rachael Brandt, William Gregory Feero, Rebecca Ferber, Veda N. Giri, Katherine Hendy, Anya E. R. Prince, Charles Lee, J. Scott Roberts

College of Life Sciences Faculty Papers

PURPOSE: This study explored employee health behavior changes and health care utilization after workplace genetic testing (wGT). Wellness-program-associated wGT seeks to improve employee health, but the related health implications are unknown.

METHODS: Employees of a large US health care system offering wGT (cancer, heart disease, and pharmacogenomics [PGx]) were sent electronic surveys. Self-reported data from those who received test results were analyzed. Descriptive statistics characterized responses, whereas logistic regression analyses explored correlates of responses to wGT.

RESULTS: 53.9% (n = 418/776) of respondents (88.3% female, mean age = 44 years) reported receiving wGT results. 12.0% (n = 48/399) received results …

Lisa Miner, Petitioner/ Appellee V. John Miner, Respondent/ Appellant : Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

Appeal from the Fifth Judicial District Court, Washington County, Utah Honorable Jeffrey C. Wilcox, Presiding

Rodney R. Parker, Attorneys for Appellant

Lindenwood Digest, May 8, 2024, Lindenwood University

Lindenwood Digest

The Lindenwood Digest has been a digital employee newsletter since 2009.

Advertising To Generation Z, Taryn Romaine

Honors College Theses

The goal of this project is to analyze the history and background of those born between 1997 and 2012, also known as Generation Z, and determine its effect on how this Generation receives and reacts to advertising. In addition, through the use of a personally created and conducted poll, I gathered data on a portion of Generation Z individuals and their preferences to certain elements of advertisement design. These elements are text content, layout, color, and relatability/authenticity. My project discusses how advertisers and advertisement designers, such as myself, can implement these preferences in order to effectively advertise to Generation Z. …

Spn 122 - Latin American Language And Culture, Salvador Salazar

Open Educational Resources

Spanish 122 provides an overview of Latin American cultures. Students will analyze and discuss representative texts and other forms of cultural production (film, visual art, music, etc.) from various regions and time periods to better understand and appreciate the diversity of Latin American history and society. The course will be conducted in Spanish.

Testing The Hypothesis That Tennis Points Are Independent And Identically Distributed Using Statistical Methods, Ernesto Ugona Santana

Senior Honors Theses

Most research on the probability of winning a tennis match is based on the assumption that the points are independent and identically distributed, treating each point as a Bernoulli trial with fixed probability of success. This assumption, however, seems to contradict experience. Players' performance appears to fluctuate as the match progresses due to the psychological effect of past performance. To test this counterintuitive yet central assumption, previous research has attempted to test the independence hypothesis. However, there exists a research gap in evaluating the identicality-of-distribution hypothesis, a question of broader scope than that of independence. Hence, the purpose of this …

Evaluating The Effect Of Noise On Secure Quantum Networks, Karthick Anbalagan

Master's Theses

This thesis focuses on examining the resilience of secure quantum networks to environmental noise. Specifically, we evaluate the effectiveness of two well-known quantum key distribution (QKD) protocols: the Coherent One-Way (COW) protocol and Kak’s Three-Stage protocol (Kak06). The thesis systematically evaluates these protocols in terms of their efficiency, operational feasibility, and resistance to noise, thereby contributing to the progress of secure quantum communications. Using simulations, this study evaluates the protocols in realistic scenarios that include factors such as noise and decoherence. The results illustrate each protocol’s relative benefits and limitations, highlighting the three-stage protocol’s superior security characteristics, resistance to interference, …

Minutes From May 8 2024, University Senate

University Senate Minutes

Minutes from May 8 2024 University Senate Meeting