Digital Commons Network^™

Unraveling Early Onset Disparities And Determinants: An Analysis Of Colorectal Cancer Outcomes And Trends In Texas, Tyler Torres, Elias Arellano Villanueva, Yossef Alsabawi, Demba Fofana, Manish Tripathi

School of Medicine Publications

Introduction: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the U.S., with disparities in incidence, survival, and age at diagnosis across racial, ethnic, and socioeconomic groups. The rising incidence of early-onset CRC (< 50 years) has amplified concerns regarding access to care, screening disparities, and outcomes, particularly among minorities. This study examines the impact of race, ethnicity, socioeconomic status (SES), and sex on CRC survival and age at diagnosis in Texas from 1995 to 2016.

Methods: This retrospective cohort study utilized Texas Cancer Registry (TCR) data, including 235,076 CRC cases diagnosed between 1995 and 2016. Kaplan-Meier analysis and log-rank tests assessed 10-year survival by race and ethnicity and time period (1995-2005 vs. 2006-2016). Kruskal-Wallis tests with Bonferroni correction were used to compare survival years between racial/ethnic groups within each period. Age at diagnosis was analyzed by race and …

Orpheus, Spring 2025: Porchswing, University Of Dayton

Orpheus: UD's Literary and Artistic Magazine

From Melina Blank, literary editor: Porchswing: According to Google, it’s “a swing on a porch usually made of wood leaving space for two people to sit and swing.” To Orpheus, it is the warm breath of familiarity that hums in one’s soul. The soul knows just about everything that inspires it, transfixes it, guides it. Home, a word we make sense of in terms of physical place, is not so definitively tangible. Instead, what inspires and transfixes and guides us could very well be a person, a song, a belief, a feeling.

If I didn’t know any better, I would …

Safety Outcomes Of Antiplatelet Therapy During Endovascular Treatment Of Tandem Lesions In Acute Ischemic Stroke Patients, Mudassir Farooqui, Afshin A. Divani, Milagros Galecio-Castillo, Ameer E. Hassan, Mouhammad A. Jumaa, Marc Ribo, Michael Abraham, Nils Petersen, Johanna T. Fifi, Wondwossen G. Tekle

School of Medicine Publications

Risk of hemorrhage remains with antiplatelet medications required with carotid stenting during endovascular therapy (EVT) for tandem lesion (TLs). We evaluated the safety of antiplatelet regimens in EVT of TLs. This multicenter study included anterior circulation TL patients from 2015 to 2020, stratified by periprocedural EVT antiplatelet strategy: (1) no antiplatelets, (2) single oral, (3) dual oral, and (4) intravenous IV (in combination with single or dual oral). Primary outcome was symptomatic intracranial hemorrhage (sICH). Secondary outcomes were any hemorrhage, favorable functional status (mRS 0-2) at 90 days, successful reperfusion (mTICI score ≥ 2b), in-stent thrombosis, and mortality at 90 …

Volume Introduction

MC Law Review

No abstract provided.

Heat-Pipe-Based Thermal Management System Design For A 250 Kw Gan-Based Integrated Modular Motor Drive, Seyed Iman Hosseini Sabzevari, Salar Koushan, Armin Ebrahimian, Towhid Islam Chowdhury, Nathan Weise, Ayman El-Refaie

Electrical and Computer Engineering Faculty Research and Publications

Integrated modular motor drive (IMMD) is an effective approach for realizing high-efficiency, high-power-density, and fault-tolerant electric machines. However, designing an efficient thermal management system (TMS) for the motor drive becomes a challenge, particularly due to space constraints. This article presents the design of a TMS based on 3-mm heat pipes for a 250-kW IMMD intended for aviation applications. The power electronics module is simulated using PLECS software where an electrothermal analysis is conducted. A simplified thermal resistance model of the system is developed to estimate the die junction temperature of gallium nitride (GaN) semiconductors. The performance of the proposed TMS …

Data Driven Multi-Objective Optimization Of The Scheduling For Towing A Floating Offshore Wind Turbine Between Assembly Port And Installation Location Throughout A Year, Frédéric Le Pivert, Adam Roberts, Adan Lopez-Santander, Matthew Craven, Saeid Kazemi

School of Engineering, Computing and Mathematics

High demand for the installation of floating offshore wind turbines over the coming years is likely to place significant pressure on ports and installation vessels. Optimization of the routes between ports and farms and the towing schedule when transporting equipment is therefore critical to reducing operation timescales and carbon emissions. This paper presents two series of multi-objective optimizations for minimizing the timescale and carbon emissions for the case of an IEA 15 MW turbine on a VolturnUS-S platform being wet towed through the English Channel to the Celtic Sea. The study makes use of the Maritime Simulation Laboratory (MSL) Ship …

Recomendaciones Para El Diseño De La Realidad Virtual Para Las Personas Mayores, Marius Varga, Leonie Cooper, Hannah Bradwell, Gaudl Swen, Alejandro Veliz Reyes, Ray Jones

School of Nursing and Midwifery

No abstract provided.

Clostridioides (Clostridium) Difficile Infection In Hospitalized Adult Patients In Cambodia, Lengsea Eng, Deirdre A. Collins, Kefyalew Addis Alene, Sotharith Bory, Youdaline Theng, Pisey Vann, Sreyhuoch Meng, Setha Limsreng, Archie C.A. Clements, Thomas V. Riley

Research outputs 2022 to 2026

Despite high levels of global concern, little is known about the epidemiology of Clostridioides (Clostridium) difficile infection (CDI) in Cambodia. This study aimed to identify the prevalence and risk factors for CDI, and molecular types of C. difficile in hospitalized adults at Calmette Hospital, Phnom Penh, Cambodia. Stool samples were collected from 263 hospitalized adults between June and September 2022 and tested for C. difficile using direct and enrichment cultures. PCR toxin genes tcdA, tcdB, cdtA, and cdtB, and amplification of the 16s–23s rRNA intergenic spacer region for ribotyping, were performed on all C. difficile isolates. C. difficile was isolated …

Comparison Between Shoulder Flexed And Extended Positions In Elbow Flexion Resistance Training On Regional Hypertrophy And Maximum Strength: Preacher Versus Bayesian Cable Curls, Parsa Attarieh, João Pedro Nunes, Saeed Khani, Saman Negahdar, Amirali Goli, Hamed Nazarirad, Shahriar Nazarirad, Shima Mojtahedi, Kazunori Nosaka, Rahman Soori

Research outputs 2022 to 2026

In the present study, the effects of resistance training on regional hypertrophy and maximum strength of the elbow flexor muscles were compared between elbow flexion exercises performed with different shoulder joint angles (∼50° of flexion vs. extension) while matched for resistance profiles. In a within-subject design, 15 young men (25.6 ± 2.1 y; 77.3 ± 6.8 kg; 175.1 ± 5.7 cm) underwent a resistance training program twice a week for 10 weeks (3–5 sets, 8–12RM), and their arms were dominant-side balanced, randomly assigned to one of the two conditions according to elbow flexion exercises: unilateral cable curl with shoulder flexed …

How Are We Preparing Australian And Aotearoa New Zealand Teachers To Be Health Promotors? Examining Physical Activity, Sleep And Sun Safety In Initial Teacher Education, Joseph J. Scott, Alexandra P. Metse, Bronwen M. Mcnoe, Sally Blane, Sharyn Chin Fat, Justine Osborne, Nicky Muir

Research outputs 2022 to 2026

Issue Addressed: While physical activity, sleep and sun safety (PASS) have been identified as important modifiable health behaviours and schools and teachers have been identified as vital for health promotion and primary prevention; little is known about how initial teacher education programs across Australia and New Zealand (NZ) are preparing future teachers to deliver PASS-related curriculum. This study investigated teacher educators' insights on their programs and their graduate's preparedness to plan and teach PASS education. Methods: Teacher educators (n = 98) from Australia and NZ completed a 30-item electronic survey. Quantitative tests were used to explore differences in the data. …

Volume 34, Number 1, Spring 2025, Office Of Communications, Illinois Wesleyan University

Illinois Wesleyan University Magazine, 2018-present

VOLUME 34 | NUMBER 1 | Spring 2025

ON OUR COVER:

The Shirk Center has been a cherished University landmark for 30 years.

22 30 Years of Shirk. In 2024, the Shirk Center reaced a new milestone with its 30th anniversary. The Center still serves as an essential community hub for campus and Bloomington-Normal.

24 A Hearth for Haiti. Kevin Hineline '88 is working with IWU physics students to develop a new cooking stove for use in the most impoverished and disaster-stricken regions of the world.

28 Setting the Standard. Jeff Becker '01 and Matt Gavin '01 are the minds …

The Roddey Mcmillan Record - April 2025, Winthrop University

The RMR 2020-2029

The Roddey McMillan Record (RMR) is Winthrop’s monthly multicultural student publication. The RMR has been a significant voice of the minority population of the Winthrop community since its creation by Gail Harris in April 1986. It promotes awareness and understanding of issues concerning minorities for the prosperity of the entire Winthrop community. The purpose of the RMR is to shine light on the many diverse cultures at Winthrop, focusing on issues, concerns and happenings of those who represent the multicultural community on campus. The Roddey McMillan Record is named after Dr. Cynthia Roddey and Atty, Sheila McMillan. Cynthia Roddey was …

Fostering Student Engagement And Initiating Class Discussions Using Vevox, Amanda Dixon

Case studies: Digital Education

Student participation and interaction in class, with lecturers and peers, is paramount to student success (Dahmani et. al., 2024). Academia is experiencing the development of a pattern of behaviour where students do not feel comfortable speaking in in front of peers and academics (Archbell & Coplan, 2022). This pattern of behaviour has a negative impact on the student experience. Legal modules in universities are focused on the theory of law and are delivered in traditional lecture format. The Business Law module in question, is delivered in two business programmes in the Faculty of Business and focuses on the theory of …

Navigating The Complexities Of End-Stage Kidney Disease (Eskd) From Risk Factors To Outcome: Insights From The Uk Biobank Cohort, Debasish Kar, Richard Byng, Aziz Sheikh, Mintu Nath, Bedowra Zabeen, Shubharthi Kar, Shakila Banu, Habibur Rahman, Navid Khan, Durjoy Acharjee, Shafiqul Islam, Victoria Allgar, Jose Ordonez-Mena, Aya El-Wazir, Soon Song, Ashish Verma, Umesh Kadam, Simon De Lusignan

Peninsula Medical School

BACKGROUND: The global prevalence of end-stage kidney disease (ESKD) is increasing despite optimal management of traditional risk factors such as hyperglycaemia, hypertension, and dyslipidaemia. This study examines the influence of cardiorenal risk factors, socioeconomic status, and ethnic and cardiovascular comorbidities on ESKD outcomes in the general population.

METHODS: This cross-sectional study analysed data from 502,408 UK Biobank study participants recruited between 2006 and 2010. Multivariable logistic regression models were fitted to assess risk factors for ESKD, with results presented as adjusted odds ratio (aOR) and 95% confidence intervals (95% CI).

RESULTS: A total of 1191 (0.2%) of the study participants …

Multiphase Iterative Algorithm For Mixed-Integer Optimal Control, Chaoying Pei, Sixiong You, Yu Di, Ran Dai

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Mixed-integer optimal control problems (MIOCPs) frequently arise in the domain of optimal control problems (OCPs) when decisions including integer variables are involved. However, existing state-of-the-art approaches for solving MIOCPs are often plagued by drawbacks such as high computational costs, low precision, and compromised optimality. In this study, we propose a novel multiphase scheme coupled with an iterative second-order cone programming (SOCP) algorithm to efficiently and effectively address these challenges in MIOCPs. In the first phase, we relax the discrete decision constraints and account for the terminal state constraints and certain path constraints by introducing them as penalty terms in the …

Chatcrs: Incorporating External Knowledge And Goal Guidance For Llm-Based Conversational Recommender Systems, Chuang Li, Yang Deng, Hengchang Hu, Min-Yen Kan, Haizhou Li

Research Collection School Of Computing and Information Systems

This paper aims to efficiently enable large language models (LLMs) to use external knowledge and goal guidance in conversational recommender system (CRS) tasks. Advanced LLMs (e.g., ChatGPT) are limited in domain-specific CRS tasks for 1) generating grounded responses with recommendation-oriented knowledge, or 2) proactively leading the conversations through different dialogue goals. In this work, we first analyze those limitations through a comprehensive evaluation, showing the necessity of external knowledge and goal guidance which contribute significantly to the recommendation accuracy and language quality. In light of this finding, we propose a novel ChatCRS framework to decompose the complex CRS task into …

Neural Multi-Objective Combinatorial Optimization Via Graph-Image Multimodal Fusion, Jinbiao Chen, Jiahai Wang, Zhiguang Cao, Yaoxin Wu

Research Collection School Of Computing and Information Systems

Existing neural multi-objective combinatorial optimization (MOCO) methods still exhibit an optimality gap since they fail to fully exploit the intrinsic features of problem instances. A significant factor contributing to this shortfall is their reliance solely on graph-modal information. To overcome this, we propose a novel graph-image multimodal fusion (GIMF) framework that enhances neural MOCO methods by integrating graph and image information of the problem instances. Our GIMF framework comprises three key components: (1) a constructed coordinate image to better represent the spatial structure of the problem instance, (2) a problem-size adaptive resolution strategy during the image construction process to improve …

Rethinking Neural Multi-Objective Combinatorial Optimization Via Neat Weight Embedding, Jinbiao Chen, Zhiguang Cao, Jiahai Wang, Yaoxin Wu, Hanzhang Qin, Zizhen Zhang, Yue-Jiao Gong

Research Collection School Of Computing and Information Systems

Recent decomposition-based neural multi-objective combinatorial optimization (MOCO) methods struggle to achieve desirable performance. Even equipped with complex learning techniques, they often suffer from significant optimality gaps in weight-specific subproblems. To address this challenge, we propose a neat weight embedding method to learn weight-specific representations, which captures weight-instance interaction for the subproblems and was overlooked by most current methods. We demonstrate the potentials of our method in two instantiations. First, we introduce a succinct addition model to learn weight-specific node embeddings, which surpassed most existing neural methods. Second, we design an enhanced conditional attention model to simultaneously learn the weight embedding …

Sita: Structurally Imperceptible And Transferable Adversarial Attacks For Stylized Image Generation, Jingdan Kang, Haoxin Yang, Yan Cai, Huaidong Zhang, Xuemiao Xu, Yong Du, Shengfeng He

Research Collection School Of Computing and Information Systems

Image generation technology has brought significant advancements across various fields but has also raised concerns about data misuse and potential rights infringements, particularly with respect to creating visual artworks. Current methods aimed at safeguarding artworks often employ adversarial attacks. However, these methods face challenges such as poor transferability, high computational costs, and the introduction of noticeable noise, which compromises the aesthetic quality of the original artwork. To address these limitations, we propose a Structurally Imperceptible and Transferable Adversarial (SITA) attacks. SITA leverages a CLIP-based destylization loss, which decouples and disrupts the robust style representation of the image. This disruption hinders …

Agentstudio: A Toolkit For Building General Virtual Agents, Longtao Zheng, Zhiyuan Huang, Zhenghai Xue, Xinrun Wang, Bo An, Shuicheng Yan

Research Collection School Of Computing and Information Systems

General virtual agents need to handle multimodal observations, master complex action spaces, and self-improve in dynamic, open-domain environments. However, existing environments are often domain-specific and require complex setups, which limits agent development and evaluation in real-world settings. As a result, current evaluations lack in-depth analyses that decompose fundamental agent capabilities. We introduce AgentStudio, a trinity of environments, tools, and benchmarks to address these issues. AgentStudio provides a lightweight, interactive environment with highly generic observation and action spaces, e.g., video observations and GUI/API actions. It integrates tools for creating online benchmark tasks, annotating GUI elements, and labeling actions in videos. Based …

Prioritizing Speech Test Cases, Zhou Yang, Jieke Shi, Muhammad Hilmi Asyrofi, Bowen Xu, Xin Zhou, Donggyun Han, David Lo

Research Collection School Of Computing and Information Systems

As Automated Speech Recognition (ASR) systems gain widespread acceptance, there is a pressing need to rigorously test and enhance their performance. Nonetheless, the process of collecting and executing speech test cases is typically both costly and time-consuming. This presents a compelling case for the strategic prioritization of speech test cases, which consist of a piece of audio and the corresponding reference text. The central question we address is: In what sequence should speech test cases be collected and executed to identify the maximum number of errors at the earliest stage? In this study, we introduce PRiOritizing sPeecH tEsT …

I Couldn't Change His Nappy: New Mothers' Experiences Of De Quervain's Tendinosis And Its Impact On Occupational Performance, Caroline Khama, Marina Ciccarelli, Julie Brayshaw, Megan Hatfield, Thuy Tran

Research outputs 2022 to 2026

Introduction: De Quervain's stenosing tendinosis (DQST) is common in new mothers because of awkward wrist postures during repetitive mothering occupations such as nursing and lifting their baby. However, little is known about how DQST affects occupations of first-time mothers. This study aimed to explore the experiences of first-time mothers living with DQST and how it affects performance of their motherhood occupations. Methods: A descriptive phenomenological study design was used. Participants were 15 first-time mothers of a child aged ≤24 months, with a current or previous diagnosis of DQST, and/or non-trauma-related symptoms of pain, tenderness, and/or swelling near the base of …

Nitrogen Processes Within Tropical Mangroves In Australia, M. F. Adame, N. Iram, J. N. Gamboa-Cutz, P. Masque

Research outputs 2022 to 2026

Coastal wetlands have long been identified as ecosystems that can ameliorate N inputs into the ocean. The processes associated with N uptake, transformation, and losses are relatively well understood for temperate wetlands; however, information on tropical wetlands is scarce. In this study, we conducted a whole ecosystem approach to measure N processes within tropical mangroves in the Moresby estuary in northeast Australia. We measured N stocks (trees and soils), inputs from sedimentation, fixation, and accumulation as woody biomass, and outputs through denitrification, anammox, and soil respiration (N2O emissions). Potential denitrification was detected along anammox (average, min-max) at 883 (485–1,450) gN …

Opportunistic Measurement Of Sagittal Abdominal Diameter With Bone Densitometry Predicts Death And Cardiovascular Events, William D. Leslie, Fatima Zarzour, Lisa M. Lix, Neil Binkley, Joshua R. Lewis, John T. Schousboe

Research outputs 2022 to 2026

Supine sagittal abdominal diameter (SAD), also known as abdominal height, has been proposed as a simple measure for assessing abdominal adiposity. We aimed to determine whether SAD from DXA performed for osteoporosis assessment predicts major adverse cardiovascular events (MACEs) using the population-based DXA registry for the Province of Manitoba, Canada. The study population comprised 72 974 individuals aged 40 yr and older with baseline DXA assessment between February 1999 and March 2018. Incident MACE (composite of all-cause mortality, acute myocardial infarction [MI], non-hemorrhagic stroke) was ascertained from linked healthcare databases. During mean 8.4 yr follow-up (611 862 person-years), 14 457 …

Resting Energy Expenditure And Metabolic Features In Children With Septo-Optic Dysplasia, David J. Cullingford, Jacqueline A. Curran, Mary B. Abraham, Aris Siafarikas, A. Marie Blackmore, Jenny Downs, Catherine S.Y. Choong

Research outputs 2022 to 2026

Context: Septo-optic dysplasia (SOD) is a major cause of congenital hypopituitarism and is known to be associated with overweight and obesity in up to 44% of children. Given the role of the hypothalamus in hormonal regulation, we sought to assess the association of resting energy expenditure (REE), appetite and physical activity with SOD. Objective: To characterize REE and other metabolic features in patients with SOD and evaluate relationships with elevated body mass index (BMI). Methods: Children with SOD above 5 years of age attending Perth Children's Hospital participated. A CosMED Q-NRG indirect calorimeter was used to calculate mean measure REE …

Revolutionizing Medical Implant Fabrication: Advances In Additive Manufacturing Of Biomedical Metals, Yuhua Li, Deyu Jiang, Rui Zhu, Chengliang Yang, Liqiang Wang, Lai Chang Zhang

Research outputs 2022 to 2026

Additive manufacturing has emerged as a transformative technology for producing biomedical metals and implants, offering the potential to revolutionize patient care and treatment outcomes. This article reviews the recent advances in additive manufacturing (AM) of biomedical metal implants, especially load-bearing biomedical alloys, biodegradable alloys, novel metals, and 4D printing, whose properties are systematically assessed to facilitate material selection for specific medical applications. The applications of the most cutting-edge artificial intelligence in AM and surface functional modification are also presented. This article also explores the application of AM in various medical specialties, such as orthopedics, dentistry, cardiology, and neurosurgery, demonstrating its …

Development Of A Reporting Guideline For Trochim’S Concept Mapping, Sandesh Pantha, Martin Jones, Richard Gray

Research outputs 2022 to 2026

Reporting guidelines are created with the intention to enhance the quality and transparency of reporting different research methods. Trochim’s concept mapping (often referred to as group concept mapping) is a six-phase, participatory mixed-method approach to understanding complex constructs. Currently, there is no reporting guideline for concept mapping. Developing a reporting guideline typically follows a three-step process: 1. a systematic review to establish the need for a reporting guideline, 2. a Delphi study to identify candidate items, and 3. consolidation process to inform a draft guideline. We have previously reported our step 1, a systematic review of health-related concept mapping studies. …

Rutting And Aging Properties Of Recycled Polymer-Modified Pavement Materials, Nuha S. Mashaan, Chathurika Dassanayake

Research outputs 2022 to 2026

Recycled polymer-modified binders have emerged as a sustainable solution for improving the performance and durability of pavement materials. This review examines the rutting and aging properties of pavements modified with recycled polymers, highlighting their potential for sustainable infrastructure development. The incorporation of recycled polymers into bitumen enhances resistance to rutting and aging by improving the binder’s mechanical stability and oxidative durability. Key laboratory techniques, including the rolling thin-film oven test (RTFOT) and the pressure aging vessel (PAV), are evaluated for their effectiveness in assessing the thermal and oxidative aging behavior of modified binders. The review demonstrates that recycled polymers improve …

The Relationship Between Visceral Fat Accumulation And Risk Of Cardiometabolic Multimorbidity: The Roles Of Accelerated Biological Aging, Tianyu Zhu, Yixing Tian, Jinqi Wang, Zhiyuan Wu, Wenhan Xie, Haotian Liu, Xia Li, Lixin Tao, Xiuhua Guo

Research outputs 2022 to 2026

Objectives: To investigate the association between visceral fat accumulation and the risk of cardiometabolic multimorbidity (CMM) and the potential roles of accelerated biological aging in this relationship. Methods: Using data from the UK Biobank, a nationwide cohort study was conducted using the available baseline body roundness index (BRI) measurement. Biological aging was assessed using the Klemera–Doubal method for biological age and the phenotypic age algorithms. The association between the BRI and CMM was estimated using the Cox proportional hazards regression model, while the roles of biological aging were examined through interaction and mediation analyses. Results: During a median follow-up of …

Lived Experience Of Regional And Remote Food Systems: Barriers To And Enablers Of Food Access In Western Australia, Stephanie L. Godrich, Jess Doe, Sarah Goodwin, Melissa Stoneham, Amanda Devine

Research outputs 2022 to 2026

Issue Addressed: To understand community and stakeholder perceptions of food supply chains in regional and remote Western Australia (WA). Methods: This qualitative study used 19 focus groups with 61 food system stakeholders and 31 community members to understand barriers to and enablers of food supply and perspectives of what good food supply chains look like. A thematic analysis of focus group transcripts was conducted. Results: Barriers included regulatory hurdles, lack of local facilities, limited food delivery, high food costs and lack of skill-sharing. Enablers included employment options, individual food processing skills, quality local food, local food awareness and emergency food …