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Systematic Review And Evidence Gap Mapping Of Alzheimer's Disease Biomarker Studies In Those With Intellectual And Developmental Disability, Lubnaa B. Abdullah, Ney Alex Alliey, Emma Elizondo, Ney Alliey Rodriguez, Gladys Maestre, James Hall Sep 2025

Systematic Review And Evidence Gap Mapping Of Alzheimer's Disease Biomarker Studies In Those With Intellectual And Developmental Disability, Lubnaa B. Abdullah, Ney Alex Alliey, Emma Elizondo, Ney Alliey Rodriguez, Gladys Maestre, James Hall

School of Medicine Publications

There are a relatively small number of investigations into brain aging in those with intellectual and developmental disability (I/DD). This project seeks to (1) characterize the internationally available multi-omics Alzheimer's disease (AD) biomarker studies including those with I/DD, and (2) discuss future research directions. PubMed, Web of Science, and Scopus were searched under the following criteria: cross-sectional or longitudinal AD-omics studies on adults (18 +) with I/DD. 532 studies were identified, 186 studies were evaluated for full-text, 79 studies were excluded, and 117 studies were extracted. Most biological specimens were analyzed in blood, plasma, or serum. Metabolomics, hormonomics, and transcriptomics …


Habit And The Potential For Actor Training With Immersive And Virtual Production Technology, John Matthews Sep 2025

Habit And The Potential For Actor Training With Immersive And Virtual Production Technology, John Matthews

School of Art, Design and Architecture

The advance of immersive and virtual technologies draws into starker contrast the analogue modalities of dominant approaches to actor training and makes more visible certain of their dynamics, which are analysed here using a philosophical framework of habit and habitus as propositionally causative. This technology is disruptive to habit and habitus in actor training and signifies potential to experiment with these dynamics to address extant problems in actor training. Problems in training habitus discussed here derive from trainers’ habits but arise primarily for trainees, and especially so for certain groups. I use Lazlo Pearlman and Deirdre McLaughlin’s critique of the …


Combining Lumipulse P-Tau217 And Aβ42/40 As Confirmatory Tests For Aβ Positivity Prior To Disease-Modifying Therapy, James D. Doecke, Ahmed Chenna, Mintzu Lo, Youssouf Badal, Brandon Yee, Robert Martone, Christos Petropoulos, Christopher J. Fowler, Simon Laws, Stephanie R. Rainey-Smith, Ralph N. Martins, Christopher C. Rowe, Colin L. Masters, John Winslow Sep 2025

Combining Lumipulse P-Tau217 And Aβ42/40 As Confirmatory Tests For Aβ Positivity Prior To Disease-Modifying Therapy, James D. Doecke, Ahmed Chenna, Mintzu Lo, Youssouf Badal, Brandon Yee, Robert Martone, Christos Petropoulos, Christopher J. Fowler, Simon Laws, Stephanie R. Rainey-Smith, Ralph N. Martins, Christopher C. Rowe, Colin L. Masters, John Winslow

Research outputs 2022 to 2026

Introduction: For a blood-based biomarker to be considered a confirmatory test for the detection of abnormal amyloid beta (Aβ) levels, the sensitivity and specificity must be equivalent to that of current cerebrospinal fluid tests. Methods: In the current study we assessed the ability of phosphorylated tau (p-tau)217 and Aβ42/40 from the Lumipulse G p-tau217 and β-amyloid ratio (1-42/1-40) tests, individually and combined, to predict Aβ positron emission tomography status in two sub-cohorts from the Australian Imaging, Biomarkers, and Lifestyle Study of Ageing. Results: Testing an Alzheimer's disease continuum cohort, the area under the curve (AUC), sensitivity, specificity, and accuracy for …


Towards Multimodal Emotional Support Conversation Systems, Yuqi Chu, Lizi Liao, Zhiyuan Zhou, Chong-Wah Ngo, Richang Hong Sep 2025

Towards Multimodal Emotional Support Conversation Systems, Yuqi Chu, Lizi Liao, Zhiyuan Zhou, Chong-Wah Ngo, Richang Hong

Research Collection School Of Computing and Information Systems

The integration of conversational artificial intelligence (AI) into mental health care promises a new horizon for therapist-client interactions, aiming to closely emulate the depth and nuance of human conversations. Despite the potential, the current landscape of conversational AI is markedly limited by its reliance on single-modal data, constraining the systems’ ability to empathize and provide effective emotional support. This limitation stems from a paucity of resources that encapsulate the multimodal nature of human communication essential for therapeutic counseling. To address this gap, we introduce the Multimodal Emotional Support Conversation (MESC) dataset, a first-of-its-kind resource enriched with comprehensive annotations across text, …


History Informing The Future Of Exercise Oncology, Daniel A. Galvão, Kerry S. Courneya, Alejandro Lucia, Anne M. May, Karen Mustian, Allison B. Warner, Wiskemann Joachim, Karen Wonders, Kathryn H. Schmitz, Robert U. Newton Sep 2025

History Informing The Future Of Exercise Oncology, Daniel A. Galvão, Kerry S. Courneya, Alejandro Lucia, Anne M. May, Karen Mustian, Allison B. Warner, Wiskemann Joachim, Karen Wonders, Kathryn H. Schmitz, Robert U. Newton

Research outputs 2022 to 2026

Exercise is increasingly recognized by patients, clinicians, and allied health professionals globally as an important component of cancer care. In this paper, we provide a viewpoint on developments in exercise oncology over the past 4 decades leading up to the creation of the International Society of Exercise Oncology (ISEO). We briefly review research in adult and pediatric cancers from early foundation studies to larger randomized controlled trials published in mainstream oncology journals alongside critical work undertaken in exercise and cancer biological mechanisms. We also discuss potential strengths, weaknesses, opportunities, and threats facing ISEO in becoming a global forum for exercise …


Closing The Youth Activity Gap Through School District–Community Partnerships, Joseph Anthes Sep 2025

Closing The Youth Activity Gap Through School District–Community Partnerships, Joseph Anthes

Journal of Youth Development

A growing divide in physical activity amongst youth, fueled by the privatization of youth athletic programs, most negatively impacts underrepresented students. Intramural-sports programs hold the potential to engage more of our youth in physical activity, including those from marginalized populations. Utilizing a collective impact approach, school-community partnerships can create opportunities for access and strive toward equity in youth health. This study evaluates a partnership between a school district and a regional health care provider that resulted in the creation of a youth intramural-sports program by describing the partnership’s implementation strategies and by comparing first year enrollment data. Implementation strategies include: …


Full Issue, Volume 20, Issue 3 Sep 2025

Full Issue, Volume 20, Issue 3

Journal of Youth Development

No abstract provided.


High-Resolution Mapping Of Alcohol-Related Brain Connectivity In Adults Using 7t Fmri And Multivoxel Pattern Classification, Alan N. Francis, Ihsan Salloum Sep 2025

High-Resolution Mapping Of Alcohol-Related Brain Connectivity In Adults Using 7t Fmri And Multivoxel Pattern Classification, Alan N. Francis, Ihsan Salloum

School of Medicine Publications

Background: Emerging evidence suggests that alcohol use disrupts large-scale brain network interactions, particularly within the triple network model-comprising the Salience Network (SN), Default Mode Network (DMN), and Frontoparietal Network (FPN). However, few studies have examined how these connectivity alterations vary across the full spectrum of alcohol consumption, especially using ultra-high-field imaging and data-driven approaches. This study leverages 7 Tesla resting-state fMRI and multivariate pattern analysis (MVPA) to characterize distinct brain connectivity patterns across heavy, moderate, and non-drinking adults, aiming to identify neural signatures that differentiate alcohol use severity levels.

Methods: We analyzed resting-state functional connectivity data from 69 adults (Mean …


Democratizing Community Discourse Analysis In Computational Social Science, Md Towhidul Absar Chowdhury Sep 2025

Democratizing Community Discourse Analysis In Computational Social Science, Md Towhidul Absar Chowdhury

Theses

Community resource inequities and undetected infrastructure vulnerabilities cost municipalities billions annually, with disproportionate impacts on marginalized communities. Current computational approaches to community needs assessment suffer from two critical limitations: they rely on aggregate-level analysis that obscures granular community expressions, and they implement sophisticated computational tools that remain inaccessible to stakeholders without technical expertise. This creates what we term the Community-Computational Gap—a persistent divide where domain experts with vital contextual knowledge cannot access the analytical tools they need, while computational experts develop models without sufficient community context. This dissertation addresses these challenges through a novel methodological framework for fine-grained utterance-level classification …


Behavioral Bias And Manager Success In Major League Baseball, Daniel Pastor, Jason R. Reed, Arjun Sondhi Sep 2025

Behavioral Bias And Manager Success In Major League Baseball, Daniel Pastor, Jason R. Reed, Arjun Sondhi

Department of Agricultural Economics Faculty Publications

Using results from 26 Major League Baseball seasons, we investigate the connection between behavior bias, managerial success, and tenure. We ask whether managers that have overachieved, relative to prior seasons, have a greater chance of remaining in that role, and if so, what was the subsequent effect on team performance. Our results indicate that MLB owners and team general managers are susceptible to behavioral biases. Team managers that overachieve in a season, relative to recent, historical team performance, endure longer tenures with their team, however, overachieving managers have statistically similar career win percentages to managers who underachieved. This result suggests …


Reimagining U.S. Tort Law For Deepfake Harms: Comparative Insights From China And Singapore, Huijuan Peng, Pey Woan Lee Sep 2025

Reimagining U.S. Tort Law For Deepfake Harms: Comparative Insights From China And Singapore, Huijuan Peng, Pey Woan Lee

Research Collection Yong Pung How School Of Law

This Article explores how U.S. tort law can respond more effectively to the distinct harms posed by deepfakes, including reputational injury, identity appropriation, and emotional distress. Traditional tort doctrines, such as defamation, the right of publicity, and intentional infliction of emotional distress (IIED), remain fragmented and ill-suited to the speed, scale, and anonymity of deepfake dissemination. Using a comparative functionalist approach, the Article analyzes how China and Singapore respond to deepfake harms through structurally divergent but functionally instructive frameworks. China’s model combines codified personality rights with intermediary obligations under a civil law regime, while Singapore adopts a hybrid approach that …


Death Penalty For Drug Offenders In Southeast Asia: Weakening Of Resistance To Change?, Wing Cheong Chan Sep 2025

Death Penalty For Drug Offenders In Southeast Asia: Weakening Of Resistance To Change?, Wing Cheong Chan

Research Collection Yong Pung How School Of Law

Although the global movement towards abolition of the death penalty has been supported by an increasing number of countries in the world, the number of persons executed for drug offences actually increased in the last few years. Known executions for drug offences now account for more than 40 per cent of all global executions. Most such executions take place in Asia. Of the 34 countries in the world that still retain the death penalty for drug offenders, all nine of those identified as “high application states” (China, Indonesia, Iran, Kuwait, Malaysia, North Korea, Saudi Arabia, Singapore and Vietnam) are found …


Catatan Managing Editor Memandang Diri Lewat Pandangan Orang Lain: Catatan Editorial Tentang Meta-Prasangka, Whinda Yustisia Sep 2025

Catatan Managing Editor Memandang Diri Lewat Pandangan Orang Lain: Catatan Editorial Tentang Meta-Prasangka, Whinda Yustisia

Jurnal Psikologi Sosial

In October 2023, when I was still living in Chicago, United States, Idhamsyah Eka Putra, one of the leading social psychology researchers, contacted me with a rather long text message. Although it was sent via a short message, the content was as complete as a proposal; it consisted of an introduction, urgency, and a forward-looking plan. He began by explaining that the concept of meta-prejudice, which he first introduced in 2014, would soon be 10 years old. To strengthen the presence of this concept, he proposed that the Journal of Social Psychology publish a Special Issue on meta-prejudice and asked …


Sisi Lain Hostile Sexism: Hubungan Negatif Dengan Metaprasangka Pada Diskriminasi Terhadap Perempuan Feminis, Vidya Ayu Cahyaningtyas, Laras Sekarasih Sep 2025

Sisi Lain Hostile Sexism: Hubungan Negatif Dengan Metaprasangka Pada Diskriminasi Terhadap Perempuan Feminis, Vidya Ayu Cahyaningtyas, Laras Sekarasih

Jurnal Psikologi Sosial

Feminism strives for gender equality, including in the workplace. However, feminism is sometimes received with hostility, as feminist women are perceived as angry and man-haters, known as misandrists. This study aims to examine the role of outgroup meta-prejudice and ingroup meta-prejudice in mediating the relationship between hostile sexism and discrimination against feminist women. A total of 708 Indonesian citizens aged at least 18 years old (Mage = 26.38, SDage = 5.65) participated in a cross-sectional online survey. The results showed that hostile sexism did not directly predict discrimination against feminist women. Instead, the association between hostile sexism and discrimination against …


Komentar Dan Arah Masa Depan Riset Meta-Prasangka Dan Pendekatan Human Nature, Idhamsyah Eka Putra Sep 2025

Komentar Dan Arah Masa Depan Riset Meta-Prasangka Dan Pendekatan Human Nature, Idhamsyah Eka Putra

Jurnal Psikologi Sosial

This paper discusses the concept of meta-prejudice and the Human Nature approach, including the research conducted and the findings obtained. Starting from the idea of meta-beliefs, Putra developed the concept of meta-prejudice to examine prejudice and intergroup hatred. Unlike Putra (2014), Cahyaningtyas (2015) applied this concept to the realm of male-female relations, particularly in relation to the feminist movement. Furthermore, based on the belief of some lay people that humans are inherently good, Putra (Putra et al., 2018; 2022) developed the Human Nature approach, which is expected to reduce prejudice and intergroup hatred. Most empirical findings so far support this …


Pengembangan Model Kedekatan Pertemanan Berdasarkan Resiprositas, Kesetaraan Dan Dukungan, Wina Aulia, Faturochman, Wenty Marina Minza Sep 2025

Pengembangan Model Kedekatan Pertemanan Berdasarkan Resiprositas, Kesetaraan Dan Dukungan, Wina Aulia, Faturochman, Wenty Marina Minza

Jurnal Psikologi Sosial

Individuals need close friends. How is close friendship developed? Generally, closeness in friendship can be developed and maintained if the relationship is equal and mutually supportive. The purpose of this research is to develop a model of friendship closeness, with reciprocity as the antecedent and equality and support as mediators. The participants in this research were 234 first-year students at Universitas Gadjah Mada. Data were collected by survey method. Closeness, reciprocity, equality and support were measured by Likert-like scales which met the criteria for psychometric property tests. Structural Equation Modeling (SEM) with four latent variables was applied to test the …


Eugenics And Polygenic Embryo Screening: Public, Clinician, And Patient Perceptions Of Conditions Versus Traits, Dorit Barlevy, Rémy A Furrer, Asha Kalapatapu, Abigail Martinez, Todd Lencz, Shai Carmi, Gabriel Lázaro-Muñoz, Stacey Pereira Sep 2025

Eugenics And Polygenic Embryo Screening: Public, Clinician, And Patient Perceptions Of Conditions Versus Traits, Dorit Barlevy, Rémy A Furrer, Asha Kalapatapu, Abigail Martinez, Todd Lencz, Shai Carmi, Gabriel Lázaro-Muñoz, Stacey Pereira

Center for Medical Ethics and Health Policy Staff Publications

Purpose: Polygenic embryo screening (PES) estimates an embryo's genetic chances of developing complex conditions (eg, cancer) and traits (eg, height). Stakeholders have raised concerns that PES promotes eugenic practices and ideology.

Methods: We surveyed a nationally representative sample of the US public on approval of screening embryos for 12 conditions and 12 traits and examined the association between disapproval and concern about eugenics. We also conducted semistructured interviews with US-based reproductive endocrinology and infertility specialists and patients undergoing in vitro fertilization on their perspectives toward PES.

Results: Among the US public (n = 1423), disapproval of screening embryos for traits …


Phytoplankton Abundance And Methane Emissions Are Minimally Impacted By Environmentally-Relevant Glyphosate Concentrations In Small-Scale Outdoor Mesocosms, Christopher F Frazier, Ted D Harris, Tonya Delsontro, Hans-Peter Grossart, Belinda S M Sturm, Jalynn M Murry, Andrew Ising Sep 2025

Phytoplankton Abundance And Methane Emissions Are Minimally Impacted By Environmentally-Relevant Glyphosate Concentrations In Small-Scale Outdoor Mesocosms, Christopher F Frazier, Ted D Harris, Tonya Delsontro, Hans-Peter Grossart, Belinda S M Sturm, Jalynn M Murry, Andrew Ising

Staff and Researcher Publications

Glyphosate is one of the most widely applied agrochemicals in North America and can be directly transported via runoff into non-target aquatic habitats. Yet, our understanding of how this herbicide affects aquatic ecosystems is limited; past studies have often focused on single species effects and/or used herbicide concentrations several orders of magnitude higher than what has been reported in contaminated aquatic systems. Further, glyphosate in aquatic systems has the potential to alter greenhouse gas emissions (methane) if it is broken down for phosphate utilization by bacteria under specific environmental conditions (i.e., oxygen, nutrient concentrations). In this study, we assessed the …


Cognitive Performance In Early Neuronal Synuclein Disease With Hyposmia But Without Motor Disability: Association With Dopamine Deficiency And Isolated Rapid Eye Movement Sleep Behavior Disorder, Daniel Weintraub, Anuprita R Nair, Ryan Kurth, Michael C Brumm, Christine Kohnen, Michele K York, Roseanne D Dobkin, Kenneth Marek, Caroline Tanner, Tanya Simuni, Andrew Siderowf, Douglas Galasko, Lana M Chahine, Christopher Coffey, Kalpana Merchant, Kathleen L Poston, Tatiana Foroud, Brit Mollenhauer, Ethan G Brown, Karl Kieburtz, Mark Frasier, Sohini Chowdhury, Roy N Alcalay, Aleksandar Videnovic, Parkinson's Progression Markers Initiative Sep 2025

Cognitive Performance In Early Neuronal Synuclein Disease With Hyposmia But Without Motor Disability: Association With Dopamine Deficiency And Isolated Rapid Eye Movement Sleep Behavior Disorder, Daniel Weintraub, Anuprita R Nair, Ryan Kurth, Michael C Brumm, Christine Kohnen, Michele K York, Roseanne D Dobkin, Kenneth Marek, Caroline Tanner, Tanya Simuni, Andrew Siderowf, Douglas Galasko, Lana M Chahine, Christopher Coffey, Kalpana Merchant, Kathleen L Poston, Tatiana Foroud, Brit Mollenhauer, Ethan G Brown, Karl Kieburtz, Mark Frasier, Sohini Chowdhury, Roy N Alcalay, Aleksandar Videnovic, Parkinson's Progression Markers Initiative

Faculty, Staff and Students Publications

Objective: To determine the impact of dopamine deficiency and isolated rapid eye movement (REM) sleep behavior disorder (iRBD) on cognitive performance in early neuronal α-synuclein disease (NSD) with hyposmia but without motor disability.

Methods: Using Parkinson's Progression Markers Initiative baseline data, cognitive performance was assessed with a cognitive summary score (CSS) derived from robust healthy control (HC) norms. Performance was examined for participants with hyposmia in early NSD-Integrated Staging System (NSD-ISS), either stage 2A (cerebrospinal fluid α-synuclein seed amplification assay [SAA]+, dopamine transporter scan [DaTscan]-) or 2B (SAA+, DaTscan+).

Results: Participants were stage 2A (n = 101), stage 2B (N …


A Prospective, Randomized, Controlled Clinical Trial Of High-Frequency Electromagnetic Coupling Powered Permanent Peripheral Nerve Stimulator For The Treatment Of Chronic Craniofacial Pain, Salim M Hayek, Nameer Haider, Ashwin Viswanathan, Mehul Desai, Jeffrey Rosenberg, Niek E Vanquathem Sep 2025

A Prospective, Randomized, Controlled Clinical Trial Of High-Frequency Electromagnetic Coupling Powered Permanent Peripheral Nerve Stimulator For The Treatment Of Chronic Craniofacial Pain, Salim M Hayek, Nameer Haider, Ashwin Viswanathan, Mehul Desai, Jeffrey Rosenberg, Niek E Vanquathem

Faculty, Staff and Students Publications

than one-fifth of the US population. While various medications and conservative treatment modalities are available for this condition, many patients have refractory symptoms. These patients suffer from social impairment, reduced quality of life, and increased financial burdens.

Objective: The objective of this study was to examine the clinical outcomes of patients receiving a permanent, high-frequency electromagnetic coupling (HF-EMC) powered peripheral nerve stimulator (PNS) system for the treatment of chronic craniofacial neuropathic pain.

Study design: This study was a multicenter, randomized, controlled clinical trial conducted under an investigational device exemption (IDE).

Setting: This study was conducted in 7 clinical sites in …


Patient-Centered Management Of Heavy Menstrual Bleeding While On Anticoagulation: A Survey Study, Benjamin Barnett, Rushad Patell, Dana Angelini, Leben Tefera, Jordan K Schaefer, Ang Li, Alejandra Gutierrez Bernal, Shruti Chaturvedi, Anjlee Mahajan, Leslie Lake, Jori May, Anna L Parks Sep 2025

Patient-Centered Management Of Heavy Menstrual Bleeding While On Anticoagulation: A Survey Study, Benjamin Barnett, Rushad Patell, Dana Angelini, Leben Tefera, Jordan K Schaefer, Ang Li, Alejandra Gutierrez Bernal, Shruti Chaturvedi, Anjlee Mahajan, Leslie Lake, Jori May, Anna L Parks

Faculty, Staff and Students Publications

Background: Nearly three-quarters of women experience heavy menstrual bleeding (HMB) during anticoagulation treatment for venous thromboembolism (VTE). HMB can lead to medical interventions, impact school or work and diminish quality of life (QOL). While there are several management options for HMB in patients with VTE, we lack information on how patients approach HMB treatment decisions.

Objectives: We examined patients' experience with, perceptions of, and preferences for treatment of HMB while on anticoagulation.

Methods: Clinicians and patient advocates developed a web-based survey that was distributed via patient advocacy organizations and social media between May and June 2024, targeting participants 18 years …


A Multi-Institutional Multi-Methods Analysis Of Jeopardy Systems In Academic Hospital Medicine, Kirsten N Kangelaris, Angela Keniston, Andrew D Auerbach, Gregory Bowling, Marisha Burden, Shradha A Kulkarni, Luci K Leykum, Anne S Linker, Matthew Sakumoto, Jeffrey Schnipper, Gopi Astik Sep 2025

A Multi-Institutional Multi-Methods Analysis Of Jeopardy Systems In Academic Hospital Medicine, Kirsten N Kangelaris, Angela Keniston, Andrew D Auerbach, Gregory Bowling, Marisha Burden, Shradha A Kulkarni, Luci K Leykum, Anne S Linker, Matthew Sakumoto, Jeffrey Schnipper, Gopi Astik

Faculty, Staff and Students Publications

Background: Hospital medicine programs use backup ("jeopardy") systems to cover unexpected staffing gaps, but little is known about their structures or optimal practices.

Objectives: To describe jeopardy structures, assess clinician perceptions, and identify potential approaches across a broad sample of hospital medicine groups.

Methods: This multi-methods study, conducted within a national hospitalist consortium, used virtual focus groups and an email survey to (1) describe the presence and structure of jeopardy systems and (2) explore features perceived as fair, equitable, and tolerable. Rapid qualitative analysis identified major themes, while descriptive methods analyzed survey data.

Results: Twenty-five individuals participated in focus groups, …


Emergency Department Utilization Among Co-Residing Family Caregivers Of Persons Living With Dementia, Pei-Chun Cha, Craig Rothenberg, Anita N Chary, Justine Seidenfeld, Ula Hwang, Terri Fried, Joan K Monin, Arjun K Venkatesh, Cameron J Gettel Sep 2025

Emergency Department Utilization Among Co-Residing Family Caregivers Of Persons Living With Dementia, Pei-Chun Cha, Craig Rothenberg, Anita N Chary, Justine Seidenfeld, Ula Hwang, Terri Fried, Joan K Monin, Arjun K Venkatesh, Cameron J Gettel

Faculty, Staff and Students Publications

No abstract provided.


Prenatal Obsessive Beliefs Predict Postpartum Obsessive-Compulsive Symptoms: A Prospective Study, Jonathan S Abramowitz, Samantha N Hellberg, Janice Krasnow, Joseph B Friedman, Nicholas S Myers, Paul S Nestadt, Heidi J Ojalehto, Emily K Juel, Jack Samuels, Mary E Kimmel, Lauren M Osborne, Eric A Storch, Gerald Nestadt, Rashelle J Musci Sep 2025

Prenatal Obsessive Beliefs Predict Postpartum Obsessive-Compulsive Symptoms: A Prospective Study, Jonathan S Abramowitz, Samantha N Hellberg, Janice Krasnow, Joseph B Friedman, Nicholas S Myers, Paul S Nestadt, Heidi J Ojalehto, Emily K Juel, Jack Samuels, Mary E Kimmel, Lauren M Osborne, Eric A Storch, Gerald Nestadt, Rashelle J Musci

Faculty, Staff and Students Publications

This longitudinal study examined whether specific cognitive patterns during pregnancy predict postpartum obsessive-compulsive (OC) symptoms. A diverse sample of 256 women was assessed at 20 weeks of pregnancy (Time 1), 6 weeks postpartum (Time 2; n = 233), and 6 months postpartum (Time 3; n = 231). At each point, participants completed interview and/or self-report measures of OC symptoms, psychological distress, and obsessive beliefs (i.e., cognitive patterns related to OC symptoms). Postpartum OC symptoms were common, reported by 87.1 % at Time 2 and 74.5 % at Time 3. Stronger prenatal obsessive beliefs during pregnancy predicted greater postpartum OC symptom …


Experiences Of Emotional Support Among Parents Of Children And Adolescents With Type 1 Diabetes: A Qualitative Study, Sahar S Eshtehardi, Marissa N Baudino, Barbara J Anderson, Deborah I Thompson, David G Marrero, Marisa E Hilliard Sep 2025

Experiences Of Emotional Support Among Parents Of Children And Adolescents With Type 1 Diabetes: A Qualitative Study, Sahar S Eshtehardi, Marissa N Baudino, Barbara J Anderson, Deborah I Thompson, David G Marrero, Marisa E Hilliard

Faculty, Staff and Students Publications

Objective: Parents of youth with type 1 diabetes (T1D) experience substantial disease-specific demands and distress, yet their perceptions about the emotional support they receive related to the challenges of caring for a child with diabetes have not been well described. This research aimed to characterize the types of emotional support parents of youth with T1D receive and how they experience emotional support.

Methods: As part of a larger qualitative study on diabetes health-related quality of life, 23 parents (96% mothers) of youth with T1D (M age = 10.9 ± 3.8 years; 35% female) completed semi-structured interviews about various aspects of …


Heightened Risk: Childhood Trauma And Anticipatory Grief Exacerbate The Impact Of Loneliness On Depressive Symptoms And Lps-Stimulated Cytokines In Dementia Caregivers, Kelly N Brice, Jensine Paoletti-Hatcher, E Lydia Wu-Chung, Vincent D Lai, Daniel L Argueta, Michelle A Chen, Itee Mahant, Bryan T Denny, Charles Green, Luis D Medina, Paul Schulz, Jennifer Stinson, Samantha K Henry, Cobi Heijnen, Christopher P Fagundes Sep 2025

Heightened Risk: Childhood Trauma And Anticipatory Grief Exacerbate The Impact Of Loneliness On Depressive Symptoms And Lps-Stimulated Cytokines In Dementia Caregivers, Kelly N Brice, Jensine Paoletti-Hatcher, E Lydia Wu-Chung, Vincent D Lai, Daniel L Argueta, Michelle A Chen, Itee Mahant, Bryan T Denny, Charles Green, Luis D Medina, Paul Schulz, Jennifer Stinson, Samantha K Henry, Cobi Heijnen, Christopher P Fagundes

Faculty, Staff and Student Publications

Dementia spousal caregivers are at a disproportionate risk for adverse mental and physical health outcomes. Loneliness is associated with depressive symptoms and proinflammatory cytokine production among caregivers. Additionally, childhood trauma, anticipatory grief, and poor sleep quality are all associated with enhanced stress reactivity. This study used a cross-sectional design to investigate whether loneliness is associated with proinflammatory cytokine production and depressive symptoms in caregivers, and whether these relationships are strongest among caregivers who report high levels of childhood trauma, high amounts of anticipatory grief, or poor sleep quality. A sample of 111 dementia spousal caregivers provided blood samples and completed …


Changes In Child Placement After Child Abuse Pediatrics Consultation For Suspected Physical Abuse, Kristine A Campbell, Antoinette L Laskey, Daniel M Lindberg, M Katherine Henry, Porcia Vaughn, James D Anderst, Megan M Letson, Angela N Bachim, Nancy S Harper, Carmen M Coombs, Lori D Frasier, Joanne N Wood Sep 2025

Changes In Child Placement After Child Abuse Pediatrics Consultation For Suspected Physical Abuse, Kristine A Campbell, Antoinette L Laskey, Daniel M Lindberg, M Katherine Henry, Porcia Vaughn, James D Anderst, Megan M Letson, Angela N Bachim, Nancy S Harper, Carmen M Coombs, Lori D Frasier, Joanne N Wood

Faculty, Staff and Students Publications

Background: The association between child abuse pediatric (CAP) assessments and child welfare outcomes is unknown.

Objective: To determine the association between a CAP determination of the likelihood of physical abuse and change in child placement. We hypothesized that child race would be associated with CAP determination of abuse likelihood and child welfare outcomes.

Participants and setting: Children under age ten years with in-person CAP consultation and referral to child protective services for suspected physical abuse at a U.S. pediatric referral center participating in CAPNET, a CAP research network, from 02/2021 to 01/2023.

Methods: We created a series of generalized estimating …


Current Controversies In Prenatal Diagnosis 2: Conventional Postmortem Examination Remains The Gold Standard For The Anatomical Examination Of Fetal Loss, J Ciaran Hutchinson, Lorraine Potocki, Ignatia B Van Den Veyver Sep 2025

Current Controversies In Prenatal Diagnosis 2: Conventional Postmortem Examination Remains The Gold Standard For The Anatomical Examination Of Fetal Loss, J Ciaran Hutchinson, Lorraine Potocki, Ignatia B Van Den Veyver

Duncan NRI Faculty and Staff Publications

A comprehensive postmortem examination is an essential component of a work-up after stillbirth. Its findings can support accurate counseling of parents about causes and risk of recurrence. It also supports providers' decisions about most appropriate testing and management plans for future pregnancy to prevent recurrence. Informing parents about fetal autopsy and obtaining their consent is challenging, and conducting a fetal autopsy requires expertise that is, not universally available. Newer non-invasive or minimally invasive methods such as postmortem MRI and targeted biopsies can replace or supplement autopsies, but one must recognize that expertise in these methods is likewise not broadly available. …


Designing An Experiment To Create And Evaluate Behavioral Changes In Air Force Pilots' Fuel Efficiency, Jackson Macias Sep 2025

Designing An Experiment To Create And Evaluate Behavioral Changes In Air Force Pilots' Fuel Efficiency, Jackson Macias

Theses and Dissertations

Fuel represents over 70% of the logistical resupply demand within the Department of Defense, with the United States Air Force accounting for most of that consumption. While prior fuel efficiency efforts have primarily focused on technical upgrades, this research explores how behavioral interventions can influence pilot decision-making and operational energy outcomes. Using the Theory of Planned Behavior (TPB) as a guiding framework, this study investigates the effects of targeted behavioral strategies on pilots’ attitudes, subjective norms, perceived behavioral control, intentions, and actual fuel-efficient behaviors. A quasi-experimental design was applied through a controlled pilot study using simulator flights. Six participants were …


The Structure Of Posttraumatic Stress Symptoms In Youth With And Without Obsessive-Compulsive Disorder: New Insights Using Factor And Network Analysis, Caitlin M Pinciotti, Matti Cervin, Kendall N Drummond, Jeffrey D Shahidullah, Justin F Rousseau, Cody G Dodd, Mercedes Ramirez, John M Hettema, Robyn Richmond, Leslie K Taylor, Lynn Monnat, Leslie Proch, Fei Teng, Wayne K Goodman, Eric A Storch, Andrew G Guzick, D Jeffrey Newport, Karen Dineen Wagner, Charles B Nemeroff Sep 2025

The Structure Of Posttraumatic Stress Symptoms In Youth With And Without Obsessive-Compulsive Disorder: New Insights Using Factor And Network Analysis, Caitlin M Pinciotti, Matti Cervin, Kendall N Drummond, Jeffrey D Shahidullah, Justin F Rousseau, Cody G Dodd, Mercedes Ramirez, John M Hettema, Robyn Richmond, Leslie K Taylor, Lynn Monnat, Leslie Proch, Fei Teng, Wayne K Goodman, Eric A Storch, Andrew G Guzick, D Jeffrey Newport, Karen Dineen Wagner, Charles B Nemeroff

Faculty, Staff and Students Publications

Posttraumatic stress disorder (PTSD) and obsessive-compulsive disorder (OCD) share ostensibly similar and sometimes overlapping symptoms that complicate diagnostic assessment and conceptualization. While varying models for the symptom structure of PTSD have been proposed - including the presently used 4-factor and a more fine-grained 7-factor model - little research has focused on youth and even less is known about how these symptoms relate to one another when OCD is present. The present study used confirmatory factor analysis (CFA) and network analysis to compare PTSD symptom relations among 2066 trauma-exposed youth aged 8-20 enrolled in the Texas Childhood Trauma Research Network, of …