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Syllabus: History 15200: The United States From The Civil War Era To The Present, Adam Kocurek Oct 2025

Syllabus: History 15200: The United States From The Civil War Era To The Present, Adam Kocurek

Open Educational Resources

This course explores the modern history of the United States with an emphasis on social and cultural history, focusing on larger societal change as well as the creation of an “American identity.” This course will particularly focus on the experiences of historically marginalized people, resistance movements, and the agents of social transformation


Product Technology Adoption And Aggregate Innovation, Qiugu He, Xuan Luo, Fan Zheng Oct 2025

Product Technology Adoption And Aggregate Innovation, Qiugu He, Xuan Luo, Fan Zheng

Research Collection School Of Economics

We document that a firm's research and development (R&D) expenditure depends on its product diversity. Combining with the fact that Chinese manufacturers often enter new product markets via technology adoption, we develop a quantitative framework of innovation and technology adoption, allowing firms to expand their product scopes. Firms adopt technologies across multiple fields to expand their knowledge base, which in turn serves as an input for subsequent innovation or adoption. Counterfactual analysis from the 2000s reveals that two-thirds of knowledge privately held by all firms is generated through adoption, accounting for one-third of aggregate innovation.


Understanding Strategies To Translate Knowledge On Hookah Smoking: A Mixed Methods Study, Rabia Mir Oct 2025

Understanding Strategies To Translate Knowledge On Hookah Smoking: A Mixed Methods Study, Rabia Mir

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: One tobacco trend of the 21 st century is smoking hookah or waterpipes. Hookah smoking is thriving on a false widespread belief that it is a safe alternate to smoking cigarettes when in fact it has adverse effects on health and is not safer. Hookah use has especially become popular for young adults and college students.

Study Objectives: The purpose of this study is to generate knowledge to inform university administration (health education personnel and campus policy makers) on what the psychosocial profile of a hookah smoker is, including risk factors, and how they can use messaging to reduce …


Examining The City Of Philadelphia’S Proposition Bill #250768 “Stop Trashing Our Air Act” By Addressing Waste Management And Environmental Justice Challenges In Chester City, Pennsylvania And The Philadelphia Region, Dylan Wascavage Oct 2025

Examining The City Of Philadelphia’S Proposition Bill #250768 “Stop Trashing Our Air Act” By Addressing Waste Management And Environmental Justice Challenges In Chester City, Pennsylvania And The Philadelphia Region, Dylan Wascavage

Student Publications

This paper offers a policy analysis of the City of Philadelphia’s "Stop Trashing Our Air Act" by summarizing the reasoning for the bill's call to action, its legislative background, identifying key players and their strategies, and how these strategies reflect philosophies of environmental governance and the policy cycle. It seeks to inform local community members and policymakers of the implications of this bill, to highlight the lack of state and federal intervention on this issue, and to address the environmental justice and pollution concerns of the Covanta waste incinerator in Chester City and its neighboring communities. It also aims to …


Trust And Ethics In Ai-Driven E-Commerce: Persuasion Vs. Privacy, Akriti Nepal Oct 2025

Trust And Ethics In Ai-Driven E-Commerce: Persuasion Vs. Privacy, Akriti Nepal

Student Publications

This study examines how AI-driven features in e-commerce influence user satisfaction and the role of trust in these interactions. Using a survey-based dataset of 100 consumers, we investigated whether trust moderates or mediates the impact of AI persuasiveness and perceptions of bias, intrusiveness, and preference understanding on satisfaction. Results indicate that AI’s perceived ability to understand user preferences strongly predicts satisfaction, while trust partially mediates the relationship between helpful AI features and urgency messages and user satisfaction. Conversely, trust did not significantly moderate these relationships, and concerns about bias and intrusiveness had minimal impact. Findings suggest that AI-driven satisfaction is …


An Analysis Of Consumer Behavior In The Brazilian E-Commerce Market: An Investigation Of Customer Loyalty, Seasonality, And Regional Preferences, Hai Doan Oct 2025

An Analysis Of Consumer Behavior In The Brazilian E-Commerce Market: An Investigation Of Customer Loyalty, Seasonality, And Regional Preferences, Hai Doan

Student Publications

This paper investigates key drivers of consumer behavior within Brazil's emerging e-commerce market by analyzing the Olist Public Dataset. As technology increasingly allows for data-driven marketing strategies, understanding the nuanced behaviors of diverse consumer bases, especially in an emerging market like Brazil, is critical for firm success. This study tests three hypotheses regarding the relationship between positive customer reviews and e-loyalty, the fluctuation of seasonal sales during holiday periods, and the influence of geographic urbanization on product preferences. Utilizing regression analyses on 100,000 orders from 2016 to 2018, the results showed no significant relationship between positive review scores and repeat …


Effectiveness Of Chinese Dual-Use Shipbuilding Within State-Owned Enterprises, Naveen Wineland Oct 2025

Effectiveness Of Chinese Dual-Use Shipbuilding Within State-Owned Enterprises, Naveen Wineland

Student Publications

This paper examines how effectively China’s state-owned enterprises (SOEs) have leveraged dual-use shipbuilding to support the naval modernization of the People’s Liberation Army Navy (PLAN). While China’s commercial shipbuilding sector now dominates the global market and provides SOEs with massive economies of scale, workforce continuity, and supply chain depth, the ability to translate these advantages into advanced naval shipbuilding has been uneven. Drawing on theoretical frameworks of the developmental state and hidden developmental state, this analysis distinguishes between commercial and naval shipbuilding requirements and examines hull-level production data for major U.S. and Chinese surface combatant classes. The evidence suggests that …


Investigating The Redox Properties Of Photoredox Catalysts And Organic Compounds Through Quantum Chemistry, Peter Girnt Oct 2025

Investigating The Redox Properties Of Photoredox Catalysts And Organic Compounds Through Quantum Chemistry, Peter Girnt

Open Access Theses & Dissertations

This dissertation explores the redox behavior of organic and organometallic systems using density functional theory (DFT), focusing on electron transfer mechanisms and structur –property relationships. The first study investigates the two-electron reduction of bianthrone isomers, revealing a potential-inverted ECE mechanism driven by isomerization and electronic destabilization. The second study examines ruthenium photoredox catalysts, showing that ligand fusion positions significantly affect redox potentials due to backbone dearomatization, while p extension has minimal impact. Together, these findings provide insight into redox tuning strategies and support the rational design of advanced catalysts and electroactive materials.


Growing South Dakota (Fall 2025), College Of Agriculture, Food And Environmental Sciences Oct 2025

Growing South Dakota (Fall 2025), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Mesonet at SDState: A benefit to every South Dakotan
[Page] 6 Governor’s Ag Ambassador — Glenn Muller
[Page] 8 Precision agriculture cooperative agreement signed with University of Debrecen
[Page] 10 Students experience international agriculture, culture in Vietnam, New Zealand
[Page] 12 Legen-dairy! SDSU students claim national judging awards
[Page] 13 SDSU Rodeo Team continues storied rodeo tradition at nationals
[Page] 14 SDSU wheat breeders helping feed the world
[Page] 20 SDSU drone holds promise for soil, leaf sampling
[Page] 22 Don't be a fish out of water
[Page] 24 A passion for academic advising
[Page] 25 One takeaway …


State Of Nev. V. Dist. Ct. (Bankhead), 141 Nev. Adv. Op. 39 (August 21, 2025), Ashley Arita Oct 2025

State Of Nev. V. Dist. Ct. (Bankhead), 141 Nev. Adv. Op. 39 (August 21, 2025), Ashley Arita

Nevada Supreme Court Summaries

No abstract provided.


An Animal Interest Approach Method As A Gateway To A One Health Educated Pipeline, Meghan C. Wulster-Radcliffe, Sarah A. Reed, James N. Macleod, Rebekah B. Epps, J. Scott Radcliffe, Robert J. Coleman, Steven A. Zinn Oct 2025

An Animal Interest Approach Method As A Gateway To A One Health Educated Pipeline, Meghan C. Wulster-Radcliffe, Sarah A. Reed, James N. Macleod, Rebekah B. Epps, J. Scott Radcliffe, Robert J. Coleman, Steven A. Zinn

Animal and Food Sciences Faculty Publications

No abstract provided.


Performance Limiting Factors For Silicon Anodes In Lithium-Ion Batteries, Najmaddin Bashirzada Oct 2025

Performance Limiting Factors For Silicon Anodes In Lithium-Ion Batteries, Najmaddin Bashirzada

Theses and Dissertations

The rising global demand for high-performance and sustainable energy storage solutions has placed lithium-ion batteries (LIBs) at the forefront of technological progress. However, the energy density limits of traditional graphite anodes require the investigation of alternative materials. Silicon (Si), with its high theoretical capacity, is a promising anode material. Still, its practical use faces major challenges such as volumetric expansion, unstable solid electrolyte interphase (SEI) formation, and low conductivity. This thesis examines the electrochemical behavior and limitations of Si-based electrodes using coin cells and ex-situ three-electrode cells. A comparison of electrochemical testing methods – i.e., Galvanostatic Intermittent Titration Technique (GITT) …


Ursinus Magazine, Fall 2025, Gundolf Graml, Steve Thomas, Jennifer L. Post-Whisted, Alyssa Kratz, Brad Drexler, Connor Donohue, Michelle Yurko Oct 2025

Ursinus Magazine, Fall 2025, Gundolf Graml, Steve Thomas, Jennifer L. Post-Whisted, Alyssa Kratz, Brad Drexler, Connor Donohue, Michelle Yurko

Ursinus Magazine, 1995–Present

Introducing Interim President Gundolf Graml • Transfer agreement signed with DCCC • New Native American and Indigenous Studies minor • Students get front-row seat to optical innovation • Study abroad expands in Ireland • Alumna earns fellowship from French government • Softball roots, Phillies dreams • New Spirit Store now open • Ursinus' youngest student: Making headlines worldwide • Alumna earns Fulbright award • Ursinus, America250PA support PA scholars • Alumni join Ursinus Board of Trustees • When generosity meets vision • Ursinus named to Phi Theta Kappa Transfer Honor Roll • Field hockey team explores South Africa • Rankings …


Examining Stress And Anxiety Levels Among Undergraduate Music Majors At The University Of South Carolina, Elise F. Halbig Oct 2025

Examining Stress And Anxiety Levels Among Undergraduate Music Majors At The University Of South Carolina, Elise F. Halbig

Senior Theses

The purpose of this study was to examine the stress and anxiety levels among undergraduate music majors at the University of South Carolina (USC) and identify potential stressors that might be unique or more prevalent among that specific population. To evaluate this, a questionnaire consisting of 42 questions was administered to participants. Most of the questions were carefully developed by the researcher; however, the Perceived Stress Scale (Cohen et al, 1983) was used to examine participants' stress levels, and 13 selected questions from the Burns Anxiety Inventory (Burns, 1989) were used to examine their anxiety levels. A total of 45 …


Is It Enough? Investigating The Effectiveness Of Adhd Accommodations For College Students, Sreekavya Mekala Oct 2025

Is It Enough? Investigating The Effectiveness Of Adhd Accommodations For College Students, Sreekavya Mekala

Senior Theses

This study explores the effectiveness of accommodations given by the University of South Carolina (USC) for students diagnosed with attention-deficit/hyperactivity disorder (ADHD). A total of 435 students completed a survey divided into three groups: those diagnosed with ADHD (n = 74), those not diagnosed but familiar with someone with ADHD (n = 321), and those not diagnosed and unfamiliar with ADHD (n = 40). Results showed that while most students with ADHD were aware of accommodations, far fewer used them, and many reported inconsistent faculty understanding and hesitation due to stigma. Students familiar with ADHD viewed accommodations as generally fair …


Recommended Best Practices For Construct-Centered Adaptation Of The Harmonized Cognitive Assessment Protocol, Emily Briceño, Darina Bassil, Pranali Khobragade, Anthony Ngugi, Martine Bejjani, Eric Ochieng, Silvia Mejia-Arango, Salima Douhou, Kazione Kulisewa, Miguel Rentería Oct 2025

Recommended Best Practices For Construct-Centered Adaptation Of The Harmonized Cognitive Assessment Protocol, Emily Briceño, Darina Bassil, Pranali Khobragade, Anthony Ngugi, Martine Bejjani, Eric Ochieng, Silvia Mejia-Arango, Salima Douhou, Kazione Kulisewa, Miguel Rentería

Population Health, East Africa

Objectives The Harmonized Cognitive Assessment Protocol (HCAP) neuropsychological assessment approach aims to support the collection of harmonizable data on cognitive function for cross-national cognitive aging and dementia research. As the measurement of cognition is sensitive to differences in contextual, cultural, educational, linguistic, social, and other factors that may influence cognitive test performance, HCAP requires adaptation to be appropriate for the contexts in which it is administered. We aim to provide methodological recommendations for the adaptation and implementation of the HCAP and other cognitive data collection tools in novel settings.

Methods We drew from existing guidelines on cross-cultural psychological test adaptation …


Msh 245 The American Musical Experience Fall 2025 Syllabus, Margaret Farrell Oct 2025

Msh 245 The American Musical Experience Fall 2025 Syllabus, Margaret Farrell

Open Educational Resources

This syllabus guided our exploration of the ways in which the musical cultures of those who arrived on our shores from Europe and Africa shaped the emergence of a distinctly American musical tradition. Links to relevant readings were provided on our LMS (Brightspace) page. Since this was an asynchronous online section, engagement was mainly through videos and slide presentations. Discussion assignments reinforced learning and encouraged critical thinking. In addition, students were required to submit a report on a live American music experience.


Impact Of Meditation Device Use On Quality Of Life Of Patients Following Surgery For Hypercortisolism, Jasmine Saini, Elio Ferreira Taveras, Yana Hleibiehova, Bahar Bahrani Fard, Malavika Suresh, Rashi Sandooja, Bahaa H Salama, Vanessa Fell, Elizabeth J Atkinson, Sara J Achenbach, Irina Bancos Oct 2025

Impact Of Meditation Device Use On Quality Of Life Of Patients Following Surgery For Hypercortisolism, Jasmine Saini, Elio Ferreira Taveras, Yana Hleibiehova, Bahar Bahrani Fard, Malavika Suresh, Rashi Sandooja, Bahaa H Salama, Vanessa Fell, Elizabeth J Atkinson, Sara J Achenbach, Irina Bancos

Faculty, Staff and Students Publications

Context: Patients with endogenous hypercortisolism experience glucocorticoid withdrawal syndrome (GWS) after surgery. Meditation may be an effective intervention to alleviate the severity of GWS.

Objective: To determine the acceptability of a portable, wearable electroencephalography device for guided meditation (MUSE headband) and the impact of MUSE use on GWS and quality of life 12 weeks postsurgery.

Methods: We conducted a single-center prospective cohort study of adults with endogenous hypercortisolism undergoing curative surgery from 2019 to 2024. Patients had baseline and postsurgical assessments over 12 weeks. The study comprised patients using MUSE for ≥ 6 weeks (MUSE cohort) and patients matched by …


Lac-Phe Induces Hypophagia By Inhibiting Agrp Neurons In Mice, Hailan Liu, Veronica L Li, Qingzhuo Liu, Yao Liu, Cunjin Su, Hueyxian Wong, Na Yin, Hesong Liu, Xing Fang, Kristine M Mcdermott, Hueyzhong Wong, Meng Yu, Longlong Tu, Jonathan C Bean, Yongxiang Li, Mengjie Wang, Yue Deng, Yuhan Shi, Olivia Z Ginnard, Yuxue Yang, Junying Han, Megan E Burt, Sanika V Jossy, Chunmei Wang, Yongjie Yang, Benjamin R Arenkiel, Dong Kong, Yang He, Jonathan Z Long, Yong Xu Oct 2025

Lac-Phe Induces Hypophagia By Inhibiting Agrp Neurons In Mice, Hailan Liu, Veronica L Li, Qingzhuo Liu, Yao Liu, Cunjin Su, Hueyxian Wong, Na Yin, Hesong Liu, Xing Fang, Kristine M Mcdermott, Hueyzhong Wong, Meng Yu, Longlong Tu, Jonathan C Bean, Yongxiang Li, Mengjie Wang, Yue Deng, Yuhan Shi, Olivia Z Ginnard, Yuxue Yang, Junying Han, Megan E Burt, Sanika V Jossy, Chunmei Wang, Yongjie Yang, Benjamin R Arenkiel, Dong Kong, Yang He, Jonathan Z Long, Yong Xu

Faculty, Staff and Students Publications

Lactate-derived N-lactoyl-phenylalanine (Lac-Phe) was recently identified as an lactate-derived circulating metabolite that reduces feeding and obesity, but mechanisms that underlie the metabolic benefits of Lac-Phe remain unknown. Here we demonstrated that Lac-Phe directly inhibits hypothalamic neurons that express Agouti-related protein (AgRP), resulting in an indirect activation of anorexigenic neurons in the paraventricular nucleus of the hypothalamus (PVH). We also found that both AgRP inhibition and PVH activation are required to mediate Lac-Phe-induced hypophagia. Further, we show that Lac-Phe inhibits AgRP neurons via activating the ATP-sensitive potassium (KATP) channel, and inhibition of the KATP channel blunts effects of Lac-Phe to suppress …


Typing Proficiency Among Physicians In Internal Medicine: A Pilot Study Of Speed And Performance, Francois Bastardot, Vanessa Kraege, Julien Castioni, Alain Petter, David W Bates, Antoine Garnier Oct 2025

Typing Proficiency Among Physicians In Internal Medicine: A Pilot Study Of Speed And Performance, Francois Bastardot, Vanessa Kraege, Julien Castioni, Alain Petter, David W Bates, Antoine Garnier

Faculty, Staff and Students Publications

Background

Electronic health records (EHRs) are widely implemented and consume nearly half of physicians' work time. Despite the importance of efficient data entry, physicians' typing skills—potential contributors to documentation burden—remain poorly studied.

Objective

This study aims to evaluate the typing skills of physicians and their associations with demographic characteristics and professional roles.

Methods

This cross-sectional pilot study included a convenience sample of physicians (residents, chief residents, and attending physicians) from the internal medicine division of an academic hospital. Participants completed a 1-minute typing test under supervised conditions. The primary outcome was raw typing speed, measured in words per minute (WPM). …


Supporting Discharge Preparation For Children With Medical Complexity: A Scoping Review, Emily Moore, Mia Waldron, Darlene Acorda, Cara Gallegos, Barbie Giambra, Stacee M. Lerret, Christine R. Platt, Danielle A. Sarik, Zara Sajwani-Merchant, Nesibe Sumeyye Kutahyalioglu, Pamela Gampetro, Susan Groshong, Marianne Weiss, Teri L. Hernandez, Sandra Staveski Oct 2025

Supporting Discharge Preparation For Children With Medical Complexity: A Scoping Review, Emily Moore, Mia Waldron, Darlene Acorda, Cara Gallegos, Barbie Giambra, Stacee M. Lerret, Christine R. Platt, Danielle A. Sarik, Zara Sajwani-Merchant, Nesibe Sumeyye Kutahyalioglu, Pamela Gampetro, Susan Groshong, Marianne Weiss, Teri L. Hernandez, Sandra Staveski

College of Nursing Faculty Research and Publications

Background

The transition from hospital to home is a critical period for children with medical complexity (CMC) and their caregivers, often associated with increased risks and stress. Both registered nurses and advanced practice nurses play a pivotal role in facilitating this transition through discharge preparation, including planning, coordination, and teaching. However, best practices for optimizing discharge processes for CMC remain unclear. The need for a comprehensive understanding of hospital discharge during this crucial time is apparent as adverse events following discharge are common and are often attributed to insufficient preparation and communication. This scoping review aims to identify key nursing …


Systematic Targeting Of Gd2-Positive Neuroblastoma Tumors With A Photooncolytic Phage Nanovector Platform, Suleman Khan Zadran, Nicola Facchinello, Piergiuseppe De Rosa, Roberto Saporetti, Paolo Emidio Costantini, Luca Ulfo, Michela Nigro, Annapaola Petrosino, Lucia Pappagallo, Sara Aloisi, Giorgio Milazzo, Zainul Abe Din, Alberto Rigamonti, Leonardo Flora, Martina Santulli, Leonardo Cimadom, Giampaolo Zuccheri, Mattia Zangoli, Manuele Di Sante, Matteo Di Giosia, Francesca Di Maria, Roberto Bernardoni, Eveline Barbieri, Matteo Calvaresi, Alberto Danielli, Giovanni Perini Oct 2025

Systematic Targeting Of Gd2-Positive Neuroblastoma Tumors With A Photooncolytic Phage Nanovector Platform, Suleman Khan Zadran, Nicola Facchinello, Piergiuseppe De Rosa, Roberto Saporetti, Paolo Emidio Costantini, Luca Ulfo, Michela Nigro, Annapaola Petrosino, Lucia Pappagallo, Sara Aloisi, Giorgio Milazzo, Zainul Abe Din, Alberto Rigamonti, Leonardo Flora, Martina Santulli, Leonardo Cimadom, Giampaolo Zuccheri, Mattia Zangoli, Manuele Di Sante, Matteo Di Giosia, Francesca Di Maria, Roberto Bernardoni, Eveline Barbieri, Matteo Calvaresi, Alberto Danielli, Giovanni Perini

Faculty, Staff and Students Publications

Disialoganglioside-GD2 is a key molecular target for Neuroblastoma (NB) immunotherapy based on the employment of GD2-targeting antibodies. However, about 50% of treated patients can experience tumor relapse due to limited immune-mediated cytotoxicity and poor antibody penetration into tumors. To address this problem, a tumor-penetrating photo-oncolytic phage nanovector platform is genetically and chemically developed that selectively targets GD2-expressing NB cells. The phage bioconjugates, functionalized with different photosensitizers, result in specific and selective oncolysis of GD2-positive NB cells upon light irradiation, without affecting GD2-negative ones. The photo-oncolytic phage vectors are shown to deeply penetrate into GD2-positive tumor spheroids in vitro, and to …


A Culturally Responsive Approach Toward Influencing General Chemistry Students’ Belonging And Perceptions Of Chemistry And Science: Metacognition Instruction Versus Role Model Narratives, Althea Berlyn, Rukayya Fall, Shanmugam Puvanendran, Jacinta M. Mutambuki Oct 2025

A Culturally Responsive Approach Toward Influencing General Chemistry Students’ Belonging And Perceptions Of Chemistry And Science: Metacognition Instruction Versus Role Model Narratives, Althea Berlyn, Rukayya Fall, Shanmugam Puvanendran, Jacinta M. Mutambuki

Chemistry Faculty Research and Publications

This study compared the influence of two distinct interventions, STEM role model narratives and metacognitive instruction, on students’ perceived sense of belonging in the General Chemistry 1 course and STEM program, as well as their perceptions of chemistry and science. We also investigated whether the influence reported differs between the two interventions and the manner in which students articulate this influence. Additionally, variations in the reported positive influence were analyzed based on gender, race/ethnicity, and first-generation status. Grounded in a culturally responsive teaching framework, the study utilized a randomized design to collect qualitative data through an open-ended questionnaire. One group …


Study Of The Ic 443 Region With The Hawc Observatory, R. Alfaro, C. Alvarez, M. Araya, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, S. Groetsch, P. Hüntemeyer, M. Najafi, R. Turner, Et. Al Oct 2025

Study Of The Ic 443 Region With The Hawc Observatory, R. Alfaro, C. Alvarez, M. Araya, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A. Ayala Solares, S. Groetsch, P. Hüntemeyer, M. Najafi, R. Turner, Et. Al

Michigan Tech Publications

Supernova remnants are one potential source class considered a PeVatron (i.e., capable of accelerating cosmic rays above PeV energies). The shock fronts produced after the explosion of the supernova are ideal regions for particle acceleration. IC 443 is a supernova remnant that has been studied extensively at different wavelengths. Using 2966 days of gamma-ray data from the High Altitude Water Cherenkov (HAWC) observatory, we study the emission of IC 443 with the objective of finding signatures of cosmic-ray acceleration at the PeV scale. Using a maximum likelihood method, we find a point source located at (α=94.°42, δ=22.°35) that we associate …


Epigenetic Age Acceleration Mediates Treatment Effects On Cardiometabolic And Cardiovascular Risk In Childhood Cancer Survivors, Xiaoxi Meng, Tiffany Eulalio, Yoonji Kim, John Easton, Heather L Mulder, Emily Walker, Geoffrey Neale, Nan Song, Kyla Shelton, Rebecca M Howell, Mengqi Xing, Sedigheh Mirzaei, Deo Kumar Srivastava, Bonnie Ky, Stephanie B Dixon, Melissa M Hudson, Kirsten K Ness, Gregory T Armstrong, Zhaoming Wang Oct 2025

Epigenetic Age Acceleration Mediates Treatment Effects On Cardiometabolic And Cardiovascular Risk In Childhood Cancer Survivors, Xiaoxi Meng, Tiffany Eulalio, Yoonji Kim, John Easton, Heather L Mulder, Emily Walker, Geoffrey Neale, Nan Song, Kyla Shelton, Rebecca M Howell, Mengqi Xing, Sedigheh Mirzaei, Deo Kumar Srivastava, Bonnie Ky, Stephanie B Dixon, Melissa M Hudson, Kirsten K Ness, Gregory T Armstrong, Zhaoming Wang

Faculty, Staff and Student Publications

BACKGROUND: Childhood cancer survivors are at increased risk for epigenetic age acceleration (EAA) and subsequent morbidities, including cardiometabolic risk factors (CMRFs) and cardiovascular diseases, because of prior genotoxic treatments.

OBJECTIVES: The aim of this study was to evaluate the mediating role of EAA in the relationship between cancer treatment exposures and risk for CMRFs and cardiovascular diseases.

METHODS: This study included 2,939 5-year survivors from SJLIFE (St. Jude Lifetime Cohort) who underwent DNA methylation profiling using peripheral blood mononuclear cells. EAA was calculated using 3 established epigenetic clocks: DunedinPACE, PCPhenoAge, and GrimAge2. Treatment data, including body region-specific radiotherapy (RT) and …


Imaging- And Tumor Biomarker-Based Multivariable Model For Early Prediction Of Pathologic Complete Response To Neoadjuvant Systemic Therapy In Triple-Negative Breast Cancer, Beatriz E Adrada, Mary S Guirguis, Lei Huo, Clinton Yam, Debu Tripathy, Rosalind Candelaria, Wei Yang, Miral Patel, Tanya Moseley, Gary J Whitman, Jessica W T Leung, Huong Le-Petross, Deanna L Lane, Nour Abuhadra, Jennifer Litton, Vicente Valero, Kelly K Hunt, Banu Arun, Rania Mohamed, Jia Sun, Anil Korkut, Sanaz Pashapoor, Jason White, Alastair Thompson, Peng Wei, Jingfei Ma, Stacy Moulder, Gaiane M Rauch Oct 2025

Imaging- And Tumor Biomarker-Based Multivariable Model For Early Prediction Of Pathologic Complete Response To Neoadjuvant Systemic Therapy In Triple-Negative Breast Cancer, Beatriz E Adrada, Mary S Guirguis, Lei Huo, Clinton Yam, Debu Tripathy, Rosalind Candelaria, Wei Yang, Miral Patel, Tanya Moseley, Gary J Whitman, Jessica W T Leung, Huong Le-Petross, Deanna L Lane, Nour Abuhadra, Jennifer Litton, Vicente Valero, Kelly K Hunt, Banu Arun, Rania Mohamed, Jia Sun, Anil Korkut, Sanaz Pashapoor, Jason White, Alastair Thompson, Peng Wei, Jingfei Ma, Stacy Moulder, Gaiane M Rauch

Faculty, Staff and Student Publications

Purpose: The response of triple-negative breast cancer (TNBC) to neoadjuvant therapy (NAT) varies widely. This study aimed to determine the performance of clinicopathologic biomarkers and volumetric changes on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in predicting pathologic complete response (pCR) to NAT in patients with TNBC.

Patients and methods: This study included 264 patients with stage I to III TNBC enrolled in a prospective clinical trial. These patients underwent DCE-MRI at baseline and after two and/or after four cycles of dose-dense anthracycline and cyclophosphamide. Tumor volume (TV) was calculated by measuring three tumor dimensions at each time point. Clinicopathologic markers …


Consensus Recommendations For Hyperpolarized [1- 13c]Pyruvate Mri Multi-Center Human Studies, Shonit Punwani, Peder E Z Larson, Christoffer Laustsen, Jan Vandermeulen, Jan Henrik Ardenkjær-Larsen, Adam W Autry, James A Bankson, Jenna Bernard, Robert Bok, Lotte Bonde Bertelsen, Jenny Che, Albert P Chen, Rafat Chowdhury, Arnaud Comment, Charles H Cunningham, Duy Dang, Ferdia A Gallagher, Adam Gaunt, Yangcan Gong, Jeremy W Gordon, Ashley Grimmer, James Grist, Esben Søvsø Szocska Hansen, Mathilde Hauge Lerche, Richard L Hesketh, Jan-Bernd Hoevener, Ching-Yi Hsieh, Kayvan R Keshari, Sebastian Kozerke, Titus Lanz, Dirk Mayer, Mary Mclean, Jae Mo Park, Jim Slater, Damian Tyler, Jean-Luc Vanderheyden, Cornelius Von Morze, Fulvio Zaccagna, Vlad Zaha, Duan Xu, Daniel Vigneron Oct 2025

Consensus Recommendations For Hyperpolarized [1- 13c]Pyruvate Mri Multi-Center Human Studies, Shonit Punwani, Peder E Z Larson, Christoffer Laustsen, Jan Vandermeulen, Jan Henrik Ardenkjær-Larsen, Adam W Autry, James A Bankson, Jenna Bernard, Robert Bok, Lotte Bonde Bertelsen, Jenny Che, Albert P Chen, Rafat Chowdhury, Arnaud Comment, Charles H Cunningham, Duy Dang, Ferdia A Gallagher, Adam Gaunt, Yangcan Gong, Jeremy W Gordon, Ashley Grimmer, James Grist, Esben Søvsø Szocska Hansen, Mathilde Hauge Lerche, Richard L Hesketh, Jan-Bernd Hoevener, Ching-Yi Hsieh, Kayvan R Keshari, Sebastian Kozerke, Titus Lanz, Dirk Mayer, Mary Mclean, Jae Mo Park, Jim Slater, Damian Tyler, Jean-Luc Vanderheyden, Cornelius Von Morze, Fulvio Zaccagna, Vlad Zaha, Duan Xu, Daniel Vigneron

Faculty, Staff and Student Publications

MRI of hyperpolarized (HP) [1‐13C]pyruvate allows in vivo assessment of metabolism and has translated into human studies across diseases at 15 centers worldwide. To determine consensus on best practice for multi‐center studies for development of clinical applications. This paper presents the results of a two‐round formal consensus building exercise carried out by experts with HP [1‐13C]pyruvate human study experience. Twenty‐nine participants from 13 sites brought together expertise in pharmacy methods, MR physics, translational imaging, and data analysis with the goal of providing recommendations and best practice statements on conduct of multi‐center human studies of HP [1‐13C]pyruvate MRI. Overall, the group …


Engaging Chinese And Korean American Communities In Dementia Research: A Journey Of Inclusivity And Partnership, Jing Wang, Xiang Qi, Mary S Mittelman, Eunjung Ko, Yaolin Pei, I Tek Leong, Sungji Park, Katherine Wang, Weiyu Mao, Cynthia Epstein, Bei Wu Oct 2025

Engaging Chinese And Korean American Communities In Dementia Research: A Journey Of Inclusivity And Partnership, Jing Wang, Xiang Qi, Mary S Mittelman, Eunjung Ko, Yaolin Pei, I Tek Leong, Sungji Park, Katherine Wang, Weiyu Mao, Cynthia Epstein, Bei Wu

Faculty, Staff and Student Publications

Introduction: The New York University Caregiver Intervention plus Enhanced Support Project is a randomized controlled trial of a family-based psychosocial intervention to enhance social support and reduce cardiometabolic risk for Chinese and Korean American dementia caregivers, using culturally tailored recruitment strategies.

Methods: We reviewed reflections from research staff, weekly meeting minutes, debriefing sessions, and progress reports, to identify key challenges and approaches to engaging participants.

Results: Key challenges included reluctance to involve family members, dementia stigma, and resistance to involving family. In response, we engaged online communities, partnered with local organizations, participated in events, and adapted recruitment messages to cultural …


Eeg And Media Multitasking: Adhd As A Moderating Factor, Xiaoying Guo Oct 2025

Eeg And Media Multitasking: Adhd As A Moderating Factor, Xiaoying Guo

Theses and Dissertations

Media use has become an integral part of everyday life. It has risen dramatically over the past century with the advent of television, computers, and digital platforms, and more recently, it has been characterized by individuals using multiple devices simultaneously (Bushman & Anderson, 2001; Nielsen Media Research, 1998; Rideout & Robb, 2019, 2021). Media multitasking (MMT) has been linked to cognitive control challenges and attentional difficulties. This study examined EEG workload (Fz theta/Pz alpha ratio), survey accuracy, and ADHD traits (ASRS v1.1) in 33 adult participants across baseline and single-versus dual-media conditions. Results indicated that mental workload was significantly higher …


Predictors Of Outpatient Follow-Up Attendance And Subsequent Psychiatric Readmission, Sandra J. Beltran Oct 2025

Predictors Of Outpatient Follow-Up Attendance And Subsequent Psychiatric Readmission, Sandra J. Beltran

Theses and Dissertations

Psychiatric readmissions remain a persistent challenge in mental health care, often reflecting gaps in continuity of treatment following discharge. The Agency for Healthcare Research and Quality (2019) indicated that a key component in preventing inpatient readmission is adequate outpatient care following discharge. Moreover, early attendance in outpatient follow-up visits is associated with improved patient outcomes (Boston Medical Center, 2022). Various predictors are associated with engagement in outpatient services, such as age, medication compliance, and socioeconomic variables (Carson et al., 2014; Li et al., 2005; Marino et al., 2016; Stubbs et al., 2024).

The present study sought to determine whether psychiatric …